Page last updated: 2024-08-20

homoarginine and Cardiovascular Diseases

homoarginine has been researched along with Cardiovascular Diseases in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's26 (83.87)24.3611
2020's5 (16.13)2.80

Authors

AuthorsStudies
Atzler, D; Böger, R; Choe, CU; Kleist, CJ; Schönhoff, M; Schwedhelm, E; Wicha, SG1
Albrecht, MH; Alizadeh, LS; Bernatz, S; Booz, C; D'Angelo, T; Eichler, K; Gruber-Rouh, T; Gruenewald, LD; Hardt, SE; Koch, V; Leistner, DM; Mahmoudi, S; Martin, SS; März, W; Nour-Eldin, NA; Scholtz, JE; Vogl, TJ; Yel, I1
Baach, F; Böger, R; Choe, CU; Lezius, S; Meyer, B; Neu, A; Oh, J; Schwedhelm, E1
Böger, R; Hannemann, J; Laing, A; Middleton, B; Schwedhelm, E; Skene, DJ1
Atzler, D; Ayers, CR; de Lemos, JA; Gore, MO; Hackler, E; Khera, A; Lew, J; Lewis, A; Neeland, I; Omland, T; Rohatgi, A1
Bakker, SJL; de Borst, MH; Hanff, E; Kayacelebi, AA; Minovic, I; Post, A; Said, MY; Tsikas, D; van den Berg, E; van Goor, H1
Böger, R; Botha-Le Roux, S; Fourie, CMT; Mels, CMC; Mokhaneli, MC; Schwedhelm, E1
Hutri-Kähönen, N; Jula, A; Juonala, M; Kähönen, M; Kangas, AJ; Lehtimäki, T; März, W; Meinitzer, A; Oksala, N; Raitakari, OT; Seppälä, I; Soininen, P1
Carru, C; Mangoni, AA; Paliogiannis, P; Zinellu, A1
Brodmann, M; Gary, T; Hackl, G; Hafner, F; Jud, P; Meinitzer, A; Seinost, G; Verheyen, N1
Adams, S; Che, D; Farouk, MH; Hailong, J; Qin, G; Rui, H1
Fromm, MF; König, J; Maas, R; Taghikhani, E1
Jarzebska, N; Karetnikova, ES; Lentz, SR; Markov, AG; Rodionov, RN; Weiss, N1
Auge, D; Chafai, A; Fromm, MF; Gessner, A; Maas, R; Mieth, M; Müller, F1
Boehm, BO; Drechsler, C; Fahrleitner-Pammer, A; Hoffmann, MM; Huang, J; Kähönen, M; Kienreich, K; Kleber, ME; Koenig, W; Krane, V; Laaksonen, R; Lehtimäki, T; Lyytikäinen, LP; Mäkelä, KM; März, W; Meinitzer, A; Oksala, N; Pilz, S; Raitakari, OT; Raitoharju, E; Seppälä, I; Tomaschitz, A; Wanner, C1
Dekker, JM; Drechsler, C; Kienreich, K; März, W; Meinitzer, A; Nijpels, G; Pilz, S; Rutters, F; Scheffer, PG; Stehouwer, CD; Teerlink, T; Tomaschitz, A1
Goniewicz, ML; Kurek, J; Prokopowicz, A; Radek, M; Sobczak, A; Szula, M; Zaciera, M2
Beckmann, B; Gutzki, FM; Jordan, J; Kayacelebi, AA; Tsikas, D1
Kayacelebi, AA; Tsikas, D1
Atzler, D; Böger, RH; Friedrich, N; Ittermann, T; Nauck, M; Schwedhelm, E1
Doerfer, J; Grulich-Henn, J; Grünert, SC; Holder, M; Krebs, A; Lichte, K; Schmidt-Trucksäss, A; Schwab, KO; Stier, B; Winkler, K; Wöhrl, J1
Atzler, D; Ayers, CR; Böger, RH; Choe, CU; de Lemos, JA; Gore, MO; McGuire, DK; Schwedhelm, E1
Döner, U; Düngen, HD; Duvinage, A; Edelmann, F; Gaksch, M; Gelbrich, G; Kienreich, K; Kunde, J; März, W; Meinitzer, A; Pieske, B; Pilz, S; Schmidt, A; Stahrenberg, R; Tomaschitz, A; Wachter, R1
Atzler, D; Choe, CU; Schwedhelm, E1
Batkai, S; Engeli, S; Jordan, J; Kayacelebi, AA; May, M; Tsikas, D1
Abedini, S; Drechsler, C; Fellstrom, B; Holdaas, H; Jardine, AG; März, W; Meinitzer, A; Pihlstrøm, H; Pilz, S; Tomaschitz, A; Wanner, C1
Aasarød, KI; Åsberg, A; Hov, GG; Sagen, E1
Appelbaum, S; Atzler, D; Beutel, ME; Blankenberg, S; Blettner, M; Böger, RH; Cordts, K; Lackner, KJ; Münzel, T; Ojeda, FM; Pfeiffer, N; Schwedhelm, E; Wild, PS; Zeller, T1
Bode-Böger, SM; Brilloff, S; Burdin, D; Cellini, B; Demyanov, A; Jarzebska, N; Kolouschek, A; Leiper, J; Maas, R; Martens-Lobenhoffer, J; Oppici, E; Rodionov, RN; Weiss, N1
Blom, HJ; Davids, M; Ndika, JD; Salomons, GS; Teerlink, T1

Reviews

6 review(s) available for homoarginine and Cardiovascular Diseases

ArticleYear
Homoarginine in the cardiovascular system: Pathophysiology and recent developments.
    Fundamental & clinical pharmacology, 2023, Volume: 37, Issue:3

    Topics: Arginine; Biomarkers; Cardiovascular Diseases; Cardiovascular System; Homoarginine; Humans

2023
Homoarginine and all-cause mortality: A systematic review and meta-analysis.
    European journal of clinical investigation, 2018, Volume: 48, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Cardiovascular Diseases; Cause of Death; Female; Homoarginine; Humans; Kaplan-Meier Estimate; Kidney Diseases; Male; Middle Aged; Observational Studies as Topic

2018
Novel Biosynthesis, Metabolism and Physiological Functions of L-Homoarginine.
    Current protein & peptide science, 2019, Volume: 20, Issue:2

    Topics: Amidinotransferases; Animals; Biosynthetic Pathways; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Energy Metabolism; Female; Fetal Growth Retardation; Homoarginine; Humans; Pregnancy; Renal Insufficiency, Chronic

2019
Is Homoarginine a Protective Cardiovascular Risk Factor?
    Arteriosclerosis, thrombosis, and vascular biology, 2019, Volume: 39, Issue:5

    Topics: Animals; Biomarkers; Cardiotonic Agents; Cardiovascular Diseases; Disease Models, Animal; Female; Homoarginine; Humans; Male; Mice; Mice, Knockout; Risk Factors; Sensitivity and Specificity

2019
Genome-wide association study identifies 3 genomic loci significantly associated with serum levels of homoarginine: the AtheroRemo Consortium.
    Circulation. Cardiovascular genetics, 2013, Volume: 6, Issue:5

    Topics: Adult; Aged; Arginine; Cardiovascular Diseases; Chromosomes, Human; Enzymes; Female; Genetic Loci; Genome-Wide Association Study; Genotype; Homoarginine; Humans; Male; Middle Aged; Mitochondria; Polymorphism, Single Nucleotide

2013
L-homoarginine and cardiovascular disease.
    Current opinion in clinical nutrition and metabolic care, 2015, Volume: 18, Issue:1

    Topics: Amidinotransferases; Amino Acid Metabolism, Inborn Errors; Animals; Cardiovascular Diseases; Developmental Disabilities; Energy Metabolism; Homoarginine; Humans; Intellectual Disability; Speech Disorders

2015

Trials

4 trial(s) available for homoarginine and Cardiovascular Diseases

ArticleYear
Tobacco smoking decreases plasma concentration of the emerging cardiovascular risk marker, L-homoarginine.
    Circulation journal : official journal of the Japanese Circulation Society, 2014, Volume: 78, Issue:5

    Topics: Adult; Biomarkers; Cardiovascular Diseases; Creatinine; Cross-Sectional Studies; Female; History, Ancient; Homoarginine; Humans; Male; Middle Aged; Risk Factors; Smoking

2014
Decreased levels of homoarginine and asymmetric dimethylarginine in children with type 1 diabetes: associations with cardiovascular risk factors but no effect by atorvastin.
    Journal of pediatric endocrinology & metabolism : JPEM, 2015, Volume: 28, Issue:1-2

    Topics: Adolescent; Anticholesteremic Agents; Arginine; Atorvastatin; Cardiovascular Diseases; Diabetes Mellitus, Type 1; Female; Follow-Up Studies; Glycated Hemoglobin; Heptanoic Acids; Homoarginine; Humans; Lipids; Male; Pilot Projects; Pyrroles; Risk Factors; Treatment Outcome

2015
Homoarginine and Clinical Outcomes in Renal Transplant Recipients: Results From the Assessment of Lescol in Renal Transplantation Study.
    Transplantation, 2015, Volume: 99, Issue:7

    Topics: Adult; Biomarkers; Cardiovascular Diseases; Chi-Square Distribution; Creatinine; Disease Progression; Europe; Fatty Acids, Monounsaturated; Female; Fluvastatin; Graft Rejection; Graft Survival; Homoarginine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Kidney Transplantation; Male; Middle Aged; Multivariate Analysis; North America; Proportional Hazards Models; Prospective Studies; Renal Insufficiency; Risk Factors; Time Factors; Treatment Outcome

2015
Reference intervals of plasma homoarginine from the German Gutenberg Health Study.
    Clinical chemistry and laboratory medicine, 2016, Jul-01, Volume: 54, Issue:7

    Topics: Adult; Aged; Cardiovascular Diseases; Case-Control Studies; Female; Germany; Homoarginine; Humans; Male; Middle Aged; Prevalence; Reference Values; Risk Factors; Tandem Mass Spectrometry

2016

Other Studies

21 other study(ies) available for homoarginine and Cardiovascular Diseases

ArticleYear
Population kinetics of homoarginine and optimized supplementation for cardiovascular risk reduction.
    Amino acids, 2022, Volume: 54, Issue:6

    Topics: Cardiovascular Diseases; Dietary Supplements; Heart Disease Risk Factors; Homoarginine; Humans; Kinetics; Risk Factors

2022
Developmental dynamics of homoarginine, ADMA and SDMA plasma levels from birth to adolescence.
    Amino acids, 2023, Volume: 55, Issue:10

    Topics: Adolescent; Adult; Arginine; Cardiovascular Diseases; Child; Child, Preschool; Heart; Homoarginine; Humans; Infant; Infant, Newborn; Renal Insufficiency, Chronic

2023
Diurnal Variation of L-Arginine and the Cardiovascular Risk Markers Asymmetric and Symmetric Dimethylarginine and Homoarginine in Rotating Night Shift Workers and Controls.
    Biomolecules, 2023, 08-22, Volume: 13, Issue:9

    Topics: Amino Acids; Arginine; Cardiovascular Diseases; Heart Disease Risk Factors; Homoarginine; Humans; Hydrocortisone; Melatonin; Risk Factors

2023
Racial Differences in Cardiovascular Biomarkers in the General Population.
    Journal of the American Heart Association, 2019, 09-17, Volume: 8, Issue:18

    Topics: Adiponectin; Adult; Albuminuria; Antibodies, Antinuclear; Arginine; Biomarkers; Black or African American; C-Reactive Protein; Cardiovascular Diseases; Cross-Sectional Studies; Female; Fibrin Fibrinogen Degradation Products; Homoarginine; Humans; Interleukin-1 Receptor-Like 1 Protein; Leptin; Linear Models; Lipoprotein(a); Male; Middle Aged; Multivariate Analysis; Natriuretic Peptide, Brain; Osteoprotegerin; Peptide Fragments; Proportional Hazards Models; Receptor for Advanced Glycation End Products; Troponin T; White People

2019
High plasma guanidinoacetate-to-homoarginine ratio is associated with high all-cause and cardiovascular mortality rate in adult renal transplant recipients.
    Amino acids, 2019, Volume: 51, Issue:10-12

    Topics: Adult; Aged; Cardiovascular Diseases; Cause of Death; Cross-Sectional Studies; Female; Follow-Up Studies; Glycine; Homoarginine; Humans; Kidney Transplantation; Male; Middle Aged; Multivariate Analysis; Proportional Hazards Models; Risk Factors

2019
L-homoarginine is associated with decreased cardiovascular- and all-cause mortality.
    European journal of clinical investigation, 2021, Volume: 51, Issue:5

    Topics: Adult; Aged; Cardiovascular Diseases; Cause of Death; Female; Homoarginine; Humans; Male; Middle Aged; Mortality; Multivariate Analysis; Proportional Hazards Models; Protective Factors

2021
The biomarker and causal roles of homoarginine in the development of cardiometabolic diseases: an observational and Mendelian randomization analysis.
    Scientific reports, 2017, 04-25, Volume: 7, Issue:1

    Topics: Adult; Biomarkers; Cardiovascular Diseases; Female; Follow-Up Studies; Homoarginine; Humans; Male; Mendelian Randomization Analysis; Metabolic Diseases; Prospective Studies; Risk Assessment; Young Adult

2017
Homoarginine/ADMA ratio and homoarginine/SDMA ratio as independent predictors of cardiovascular mortality and cardiovascular events in lower extremity arterial disease.
    Scientific reports, 2018, 09-21, Volume: 8, Issue:1

    Topics: Aged; Arginine; Biomarkers; Cardiovascular Diseases; Cardiovascular System; Female; Homoarginine; Humans; Incidence; Lower Extremity; Male; Middle Aged; Prospective Studies; Risk Factors; Vascular Diseases

2018
The renal transport protein OATP4C1 mediates uptake of the uremic toxin asymmetric dimethylarginine (ADMA) and efflux of cardioprotective L-homoarginine.
    PloS one, 2019, Volume: 14, Issue:3

    Topics: Arginine; Cardiovascular Diseases; HEK293 Cells; Homoarginine; Humans; Inhibitory Concentration 50; Kidney; Kinetics; Organic Anion Transporters; Toxins, Biological

2019
Establishment of reference values for the lysine acetylation marker N
    Amino acids, 2019, Volume: 51, Issue:9

    Topics: Adolescent; Adult; Arginine; Biomarkers; Cardiovascular Diseases; Carnitine; Chromatography, Liquid; Citrulline; Creatinine; Female; Homoarginine; Humans; Lysine; Male; Middle Aged; Ornithine; Reference Values; Renal Insufficiency, Chronic; Tandem Mass Spectrometry; Young Adult

2019
Homoarginine and mortality in an older population: the Hoorn study.
    European journal of clinical investigation, 2014, Volume: 44, Issue:2

    Topics: Age Factors; Aged; Cardiovascular Diseases; Epidemiologic Methods; Female; Homoarginine; Humans; Male; Middle Aged; Netherlands

2014
GC-MS and GC-MS/MS measurement of the cardiovascular risk factor homoarginine in biological samples.
    Amino acids, 2014, Volume: 46, Issue:9

    Topics: Arginine; Cardiovascular Diseases; Female; Gas Chromatography-Mass Spectrometry; Homoarginine; Humans; Male; Risk Factors; Sputum

2014
Do homoarginine and asymmetric dimethylarginine act antagonistically in the cardiovascular system?
    Circulation journal : official journal of the Japanese Circulation Society, 2014, Volume: 78, Issue:8

    Topics: Cardiovascular Diseases; Female; Homoarginine; Humans; Male; Smoking

2014
Do homoarginine and asymmetric dimethylarginine act antagonistically in the cardiovascular system?
    Circulation journal : official journal of the Japanese Circulation Society, 2014, Volume: 78, Issue:8

    Topics: Cardiovascular Diseases; Female; Homoarginine; Humans; Male; Smoking

2014
Serum reference intervals of homoarginine, ADMA, and SDMA in the study of health in Pomerania.
    Clinical chemistry and laboratory medicine, 2014, Volume: 52, Issue:12

    Topics: Adult; Aged; Arginine; Biomarkers; Body Mass Index; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Female; Homoarginine; Humans; Male; Middle Aged; Reference Values; Renal Insufficiency, Chronic; Risk Factors; Tandem Mass Spectrometry

2014
Homoarginine and cardiovascular outcome in the population-based Dallas Heart Study.
    Arteriosclerosis, thrombosis, and vascular biology, 2014, Volume: 34, Issue:11

    Topics: Adult; Aorta; Biomarkers; Cardiovascular Diseases; Cross-Sectional Studies; Female; Follow-Up Studies; Homoarginine; Humans; Incidence; Male; Middle Aged; Proportional Hazards Models; Risk Factors; Texas; Ultrasonography

2014
Associations of methylarginines and homoarginine with diastolic dysfunction and cardiovascular risk factors in patients with preserved left ventricular ejection fraction.
    Journal of cardiac failure, 2014, Volume: 20, Issue:12

    Topics: Aged; Aged, 80 and over; Arginine; Biomarkers; Cardiovascular Diseases; Echocardiography, Doppler; Female; Heart Failure, Diastolic; Homoarginine; Humans; Logistic Models; Male; Middle Aged; Nitric Oxide; Reference Values; Risk Factors; Sensitivity and Specificity; Severity of Illness Index; Stroke Volume

2014
Plasma and tissue homoarginine concentrations in healthy and obese humans.
    Amino acids, 2015, Volume: 47, Issue:9

    Topics: Adult; Bariatric Surgery; Body Mass Index; Cardiovascular Diseases; Female; Homoarginine; Humans; Male; Obesity; Risk Factors

2015
Arginine, dimethylated arginine and homoarginine in relation to cardiovascular risk in patients with moderate chronic kidney disease.
    Clinical biochemistry, 2015, Volume: 48, Issue:10-11

    Topics: Adult; Aged; Arginine; Biomarkers; Cardiovascular Diseases; Female; Follow-Up Studies; Homoarginine; Humans; Male; Middle Aged; Prospective Studies; Renal Insufficiency, Chronic; Risk Factors

2015
A Novel Pathway for Metabolism of the Cardiovascular Risk Factor Homoarginine by alanine:glyoxylate aminotransferase 2.
    Scientific reports, 2016, 10-18, Volume: 6

    Topics: Animals; Cardiovascular Diseases; Genome-Wide Association Study; Hep G2 Cells; Homoarginine; Humans; Metabolic Networks and Pathways; Metabolic Syndrome; Mice; Mice, Knockout; Mice, Transgenic; Risk Factors; Stroke; Transaminases

2016
Promiscuous activity of arginine:glycine amidinotransferase is responsible for the synthesis of the novel cardiovascular risk factor homoarginine.
    FEBS letters, 2012, Oct-19, Volume: 586, Issue:20

    Topics: Amidinotransferases; Amino Acid Metabolism, Inborn Errors; Cardiovascular Diseases; Developmental Disabilities; Homoarginine; Humans; Infant, Newborn; Intellectual Disability; Male; Risk Factors; Speech Disorders; Substrate Specificity

2012