histrelin and Chemical-and-Drug-Induced-Liver-Injury

Drug-induced liver injury (DILI) is the leading cause of acute hepatic failure in the United States. Up to 13% of acute liver failure cases occur due to drugs other than acetaminophen. This clinical diagnosis, made after other causes of liver injury have been excluded, requires establishing a causal relationship between drug exposure and liver injury. The case of a patient with liver injury following a subcutaneous histrelin (Vantus) implant as therapy for advanced prostate cancer is presented.

Topics: Aged; Antineoplastic Agents, Hormonal; Chemical and Drug Induced Liver Injury; Drug Implants; Gonadotropin-Releasing Hormone; Humans; Male