histamine has been researched along with Rhinitis, Allergic in 59 studies
Rhinitis, Allergic: An inflammation of the NASAL MUCOSA triggered by ALLERGENS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "OVA treatment successfully induced AR model in mice with significantly increased sneezing and rubbing frequency, elevated levels of serum histamine, IL-1β, IL-10 and OVA-specific IgE." | 8.31 | Bufotalin ameliorates ovalbumin-induced allergic rhinitis by restoring the Tregs. ( Ji, Q; Li, L; Ren, S, 2023) |
| "Allergic rhinitis (AR), histamine-mediated upper airway inflammatory disorder, is characterized by sneezing, itching, airway hyperreactivity, etc." | 8.02 | Chitosan-centered nanosystems as sustained therapeutics for allergic rhinitis intervention: Inhibition of histamine-induced cascades. ( Chen, X; Fan, P; Liu, Y; Qin, D; Sun, M, 2021) |
| " The purpose of this study is to investigate the anti-allergic effect of TSL in ovalbumin (OVA)-induced allergic rhinitis (AR) guinea pigs and immunoglobulin E (IgE)-stimulated RBL-2H3 cells." | 7.96 | Tussilagone inhibits allergic responses in OVA-induced allergic rhinitis guinea pigs and IgE-stimulated RBL-2H3 cells. ( Jin, C; Liu, L; Luan, H; Wang, Y; Yang, S; Ye, K; Zhang, R, 2020) |
| " essential oil (AEO) on ovalbumin (OVA)-induced allergic rhinitis (AR) in rats." | 7.96 | Protective effect of Asarum sieboldii essential oil on ovalbumin induced allergic rhinitis in rat. ( Kang, H; Zhang, Z, 2020) |
| "To investigate the association between histamine skin reactivity and body mass index (BMI) and other clinical factors, 526 children (3-6 years old) who underwent a skin-prick test (SPT) to diagnose allergic rhinitis were enrolled." | 7.91 | Association of body mass index and season with histamine skin reactivity in Chinese children with allergic rhinitis. ( Gu, M; Yang, Y, 2019) |
| " Furthermore, we assessed the therapeutic effects of taurine on ovalbumin (OVA)-induced allergic rhinitis (AR) animal models." | 7.85 | The potential protective role of taurine against experimental allergic inflammation. ( Jeong, HJ; Kim, HM; Nam, SY, 2017) |
| " In an ovalbumin-induced model of allergic rhinitis in guinea pigs, the number of sneezing, nasal rubbing, and nasal secretion events were assessed after the nasal cavity instillation of PGD2, histamine, or a combination of PGD2and histamine." | 7.83 | Prostaglandin D2 Modulates Neuronal Excitation of the Trigeminal Ganglion to Augment Allergic Rhinitis in Guinea Pigs. ( Aoki, M; Furue, S; Goto, K; Inagaki, N; Nagira, Y; Shichijo, M; Tanaka, H; Tomita, Y, 2016) |
| "This study is aimed at exploring the effect of Bencycloquidium bromide (BCQB), a novel M1/M3 receptor antagonist, on mucus secretion in a murine model of allergic rhinitis (AR)." | 7.81 | Bencycloquidium bromide inhibits nasal hypersecretion in a rat model of allergic rhinitis. ( Huang, J; Li, J; Long, R; Meng, L; Peng, L; Zhou, Y; Zhu, S, 2015) |
| "Pretreatment with histamine receptor-1 antagonist, azelastine prevented the early effect of nasal secretions of AR patients on epithelial integrity." | 6.87 | Histamine and T helper cytokine-driven epithelial barrier dysfunction in allergic rhinitis. ( Akdis, CA; Boeckxstaens, G; Boon, L; Bullens, DM; Ceuppens, JL; Farré, R; Hellings, PW; Kortekaas Krohn, I; Raap, U; Seys, SF; Steelant, B; Talavera, K; Van Gerven, L; Van Woensel, M; Wawrzyniak, P, 2018) |
| "Ebastine is a well-established secondgeneration oral H1-antihistamine that is administered once daily at a dose of 10-20 mg and is available both as a standard tablet and as a fast-dissolving tablet that disintegrates in the mouth." | 6.66 | Ebastine in the Treatment of Allergic Rhinitis and Urticaria: 30 Years of Clinical Studies and Real-World Experience. ( Sastre, J, 2020) |
| "Allergic rhinitis is a common heterogeneous chronic upper airway disorder and is an IgE-mediated inflammation characterized by one or more nasal symptoms such as sneezing, itching, nasal discharge, rhinorrhea, post nasal drainage and nasal blockage." | 5.46 | Skullcapflavone II attenuates ovalbumin-induced allergic rhinitis through the blocking of Th2 cytokine production and mast cell histamine release. ( Bui, TT; Chai, OH; Piao, CH; Song, CH, 2017) |
| "Piperine (PIP) has been reported to exhibit anti-inflammatory, anti-histaminic, and immunomodulatory activities; however, its antiallergic profile has not been studied." | 5.42 | Antiallergic effect of piperine on ovalbumin-induced allergic rhinitis in mice. ( Aswar, M; Aswar, U; Chepurwar, S; Shintre, S, 2015) |
| "Kaempferol (KP) is a major compound of Naju Jjok (Polygonum tinctorium Lour." | 5.39 | Evaluation of the effect of kaempferol in a murine allergic rhinitis model. ( Han, NR; Jeong, HJ; Kim, HM; Kim, MJ; Oh, HA, 2013) |
| "OVA treatment successfully induced AR model in mice with significantly increased sneezing and rubbing frequency, elevated levels of serum histamine, IL-1β, IL-10 and OVA-specific IgE." | 4.31 | Bufotalin ameliorates ovalbumin-induced allergic rhinitis by restoring the Tregs. ( Ji, Q; Li, L; Ren, S, 2023) |
| " The effect of the DPP4 inhibitor sitagliptin on the effector phase of allergic rhinitis (AR) in ovalbumin (OVA)-sensitized mice and on mast cell degranulation in vitro was assessed." | 4.31 | DPP4 Inhibitor Sitagliptin Reduces Inflammatory Responses and Mast Cell Activation in Allergic Rhinitis. ( Sun, X; Xu, Y; Zhou, J, 2023) |
| " We investigated AR-related behavior (sneezing and nose rubbing), as well as total immunoglobulin E (IgE), histamine, interleukin-4 (IL-4), leukotriene (LT) B4 and LTC4 levels, and gene expression of CysLT1R, HRH1, and MUC5a." | 4.12 | Effect of Temperature and Humidity on the Allegro-inflammatory Factors and Allergic Rhinitis-related Behavior. ( Liuo, Y; Mehrabi Nasab, E; Yonghua, S, 2022) |
| "Current medications to treat allergic rhinitis (AR) include antihistamines, corticosteroids, and anti-leukotrienes." | 4.12 | The Effects of Combined Therapeutic Protocol on Allergic Rhinitis Symptoms and Molecular Determinants. ( Athari, SS; Hassanpour, F; Mehrabi Nasab, E; Shen, Y, 2022) |
| "Allergic rhinitis (AR), histamine-mediated upper airway inflammatory disorder, is characterized by sneezing, itching, airway hyperreactivity, etc." | 4.02 | Chitosan-centered nanosystems as sustained therapeutics for allergic rhinitis intervention: Inhibition of histamine-induced cascades. ( Chen, X; Fan, P; Liu, Y; Qin, D; Sun, M, 2021) |
| " The purpose of this study is to investigate the anti-allergic effect of TSL in ovalbumin (OVA)-induced allergic rhinitis (AR) guinea pigs and immunoglobulin E (IgE)-stimulated RBL-2H3 cells." | 3.96 | Tussilagone inhibits allergic responses in OVA-induced allergic rhinitis guinea pigs and IgE-stimulated RBL-2H3 cells. ( Jin, C; Liu, L; Luan, H; Wang, Y; Yang, S; Ye, K; Zhang, R, 2020) |
| " essential oil (AEO) on ovalbumin (OVA)-induced allergic rhinitis (AR) in rats." | 3.96 | Protective effect of Asarum sieboldii essential oil on ovalbumin induced allergic rhinitis in rat. ( Kang, H; Zhang, Z, 2020) |
| "To investigate the association between histamine skin reactivity and body mass index (BMI) and other clinical factors, 526 children (3-6 years old) who underwent a skin-prick test (SPT) to diagnose allergic rhinitis were enrolled." | 3.91 | Association of body mass index and season with histamine skin reactivity in Chinese children with allergic rhinitis. ( Gu, M; Yang, Y, 2019) |
| "Geraniol is a monoterpene alcohol that has anti-fungal, anti-cancer and anti-nociceptive properties, but its anti-allergic rhinitis (AR) property is unclear." | 3.88 | Geraniol suppresses proinflammatory mediators in phorbol 12-myristate 13-acetate with A23187-induced HMC-1 cells. ( Huang, Y; Ni, YH; Xu, ZM; Yang, XL, 2018) |
| "Both histamine and leukotrienes are implicated in the pathogenesis of allergic rhinitis (AR), although the pattern and severity of the nasal response to these two potent inflammatory mediators may differ, which has not been adequately studied in patients with persistent AR." | 3.88 | Effects of leukotriene D ( Gao, Y; Guan, W; Huang, R; Xia, S; Xie, Y; Zheng, J; Zhong, N; Zhu, Z, 2018) |
| " Furthermore, we assessed the therapeutic effects of taurine on ovalbumin (OVA)-induced allergic rhinitis (AR) animal models." | 3.85 | The potential protective role of taurine against experimental allergic inflammation. ( Jeong, HJ; Kim, HM; Nam, SY, 2017) |
| "Human nasal epithelial cells from allergic rhinitis patients were cultured, and stimulated with 4 concentrations of histamine, or pretreated with a specific nuclear factor-kappa B (NF-κB) inhibitor (Bay11-7082) before histamine stimulation." | 3.83 | The role for human nasal epithelial nuclear factor kappa B activation in histamine-induced mucin 5 subtype B overproduction. ( Shao, S; Wang, S; Wang, W, 2016) |
| "Histamine H1 receptor (H1R) gene is upregulated in patients with allergic rhinitis (AR), and its expression level is strongly correlated with the severity of allergic symptoms." | 3.83 | A novel benzofuran, 4-methoxybenzofuran-5-carboxamide, from Tephrosia purpurea suppressed histamine H1 receptor gene expression through a protein kinase C-δ-dependent signaling pathway. ( Fukui, H; Kadota, T; Karmakar, S; Kashiwada, Y; Kitamura, Y; Mizuguchi, H; Mukherjee, PK; Nemoto, H; Shill, MC; Takeda, N, 2016) |
| " In an ovalbumin-induced model of allergic rhinitis in guinea pigs, the number of sneezing, nasal rubbing, and nasal secretion events were assessed after the nasal cavity instillation of PGD2, histamine, or a combination of PGD2and histamine." | 3.83 | Prostaglandin D2 Modulates Neuronal Excitation of the Trigeminal Ganglion to Augment Allergic Rhinitis in Guinea Pigs. ( Aoki, M; Furue, S; Goto, K; Inagaki, N; Nagira, Y; Shichijo, M; Tanaka, H; Tomita, Y, 2016) |
| " Treatment with TAPP-CZ (10 and 30 µg/kg in nostril) showed significant attenuation in OVA-induced alterations of the nasal (number of nasal rubbing and sneezing), biochemical markers (serum IgE and histamine), haematological, morphological (relative organ weight of spleen and lung) and histopathological (nasal mucosa and spleen) parameters." | 3.81 | Anti-allergic effect of intranasal administration of type-A procyanidin polyphenols based standardized extract of cinnamon bark in ovalbumin sensitized BALB/c mice. ( Aswar, UM; Kandhare, AD; Mohan, V; Thakurdesai, PA, 2015) |
| "This study is aimed at exploring the effect of Bencycloquidium bromide (BCQB), a novel M1/M3 receptor antagonist, on mucus secretion in a murine model of allergic rhinitis (AR)." | 3.81 | Bencycloquidium bromide inhibits nasal hypersecretion in a rat model of allergic rhinitis. ( Huang, J; Li, J; Long, R; Meng, L; Peng, L; Zhou, Y; Zhu, S, 2015) |
| " The present study investigated the effects and mechanism of BS, SDS, NaCl, or mineral mixture (containing zinc, magnesium, and potassium) on ovalbumin (OVA)-induced allergic rhinitis (AR) animal model." | 3.78 | Bamboo salt reduces allergic responses by modulating the caspase-1 activation in an OVA-induced allergic rhinitis mouse model. ( Jeong, HJ; Kim, HM; Kim, KY; Nam, SY; Park, KY; Shin, TY, 2012) |
| "Pretreatment with histamine receptor-1 antagonist, azelastine prevented the early effect of nasal secretions of AR patients on epithelial integrity." | 2.87 | Histamine and T helper cytokine-driven epithelial barrier dysfunction in allergic rhinitis. ( Akdis, CA; Boeckxstaens, G; Boon, L; Bullens, DM; Ceuppens, JL; Farré, R; Hellings, PW; Kortekaas Krohn, I; Raap, U; Seys, SF; Steelant, B; Talavera, K; Van Gerven, L; Van Woensel, M; Wawrzyniak, P, 2018) |
| "Ebastine is a well-established secondgeneration oral H1-antihistamine that is administered once daily at a dose of 10-20 mg and is available both as a standard tablet and as a fast-dissolving tablet that disintegrates in the mouth." | 2.66 | Ebastine in the Treatment of Allergic Rhinitis and Urticaria: 30 Years of Clinical Studies and Real-World Experience. ( Sastre, J, 2020) |
| "Allergic rhinitis is a common heterogeneous chronic upper airway disorder and is an IgE-mediated inflammation characterized by one or more nasal symptoms such as sneezing, itching, nasal discharge, rhinorrhea, post nasal drainage and nasal blockage." | 1.46 | Skullcapflavone II attenuates ovalbumin-induced allergic rhinitis through the blocking of Th2 cytokine production and mast cell histamine release. ( Bui, TT; Chai, OH; Piao, CH; Song, CH, 2017) |
| "Histamine is an important mediator of allergic reactions, and mucus hypersecretion is a major allergic symptom." | 1.46 | Synergistic mucus secretion by histamine and IL-4 through TMEM16A in airway epithelium. ( Cho, HJ; Choi, JY; Kang, JW; Kang, MJ; Kim, CH; Lee, HJ; Lee, SN; Lee, YH; Min, HJ; Namkung, W; Oh, R; Yoon, JH, 2017) |
| "Piperine (PIP) has been reported to exhibit anti-inflammatory, anti-histaminic, and immunomodulatory activities; however, its antiallergic profile has not been studied." | 1.42 | Antiallergic effect of piperine on ovalbumin-induced allergic rhinitis in mice. ( Aswar, M; Aswar, U; Chepurwar, S; Shintre, S, 2015) |
| "Histamine is the main cause of sneezing and hypersecretion, while other mediators probably also play a role in nasal blockage." | 1.40 | Allergic rhinitis. ( Mygind, N, 2014) |
| "Kaempferol (KP) is a major compound of Naju Jjok (Polygonum tinctorium Lour." | 1.39 | Evaluation of the effect of kaempferol in a murine allergic rhinitis model. ( Han, NR; Jeong, HJ; Kim, HM; Kim, MJ; Oh, HA, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (5.08) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 33 (55.93) | 24.3611 |
| 2020's | 23 (38.98) | 2.80 |
| Authors | Studies |
|---|---|
| Guo, J | 1 |
| Xu, S | 2 |
| Li, E | 1 |
| Wang, D | 3 |
| Xue, Y | 1 |
| Yan, J | 1 |
| Wang, J | 8 |
| Wang, S | 2 |
| Wang, L | 5 |
| Hu, H | 2 |
| Dong, P | 1 |
| Shen, Y | 2 |
| Mehrabi Nasab, E | 2 |
| Hassanpour, F | 1 |
| Athari, SS | 1 |
| Liu, C | 3 |
| Pang, C | 1 |
| Chen, DS | 1 |
| Yi, WQ | 1 |
| Yu, N | 1 |
| Chen, L | 3 |
| Kuang, Y | 1 |
| Hu, B | 2 |
| Huang, M | 2 |
| Zhao, S | 2 |
| Wu, X | 3 |
| Zhang, M | 2 |
| Xie, Z | 1 |
| Xu, H | 3 |
| Chen, H | 1 |
| Cai, H | 1 |
| Ji, Q | 3 |
| Ren, S | 3 |
| Li, L | 7 |
| Yonghua, S | 1 |
| Liuo, Y | 1 |
| Sun, X | 3 |
| Xu, Y | 3 |
| Zhou, J | 2 |
| Jung, MA | 1 |
| Song, HK | 1 |
| Jo, K | 2 |
| Lee, A | 1 |
| Hwang, YH | 1 |
| Ji, KY | 1 |
| Jung, DH | 1 |
| Cai, M | 1 |
| Lee, JY | 1 |
| Pyun, BJ | 1 |
| Kim, T | 1 |
| Kim, HY | 3 |
| Kim, J | 1 |
| Jeong, HJ | 7 |
| Kim, HM | 7 |
| Jin, C | 1 |
| Ye, K | 1 |
| Luan, H | 1 |
| Liu, L | 2 |
| Zhang, R | 2 |
| Yang, S | 2 |
| Wang, Y | 10 |
| Halim, AA | 1 |
| Alsayed, B | 1 |
| Embarak, S | 1 |
| Yaseen, T | 1 |
| Dabbous, S | 1 |
| Fontaine, O | 1 |
| Dueluzeau, R | 1 |
| Raibaud, P | 1 |
| Chabanet, C | 1 |
| Popoff, MR | 1 |
| Badoual, J | 1 |
| Gabilan, JC | 1 |
| Andremont, A | 1 |
| Gómez, L | 1 |
| Andrés, S | 1 |
| Sánchez, J | 1 |
| Alonso, JM | 1 |
| Rey, J | 1 |
| López, F | 1 |
| Jiménez, A | 1 |
| Yan, Z | 2 |
| Zhou, L | 1 |
| Zhao, Y | 3 |
| Huang, L | 2 |
| Hu, K | 1 |
| Liu, H | 4 |
| Wang, H | 4 |
| Guo, Z | 1 |
| Song, Y | 1 |
| Huang, H | 4 |
| Yang, R | 1 |
| Owen, TW | 1 |
| Al-Kaysi, RO | 1 |
| Bardeen, CJ | 1 |
| Cheng, Q | 1 |
| Wu, S | 1 |
| Cheng, T | 1 |
| Zhou, X | 1 |
| Wang, B | 4 |
| Zhang, Q | 5 |
| Yao, Y | 3 |
| Ochiai, T | 1 |
| Ishiguro, H | 2 |
| Nakano, R | 2 |
| Kubota, Y | 2 |
| Hara, M | 1 |
| Sunada, K | 1 |
| Hashimoto, K | 1 |
| Kajioka, J | 1 |
| Fujishima, A | 1 |
| Jiao, J | 3 |
| Gai, QY | 3 |
| Wang, W | 3 |
| Zang, YP | 2 |
| Niu, LL | 2 |
| Fu, YJ | 3 |
| Wang, X | 4 |
| Yao, LP | 1 |
| Qin, QP | 1 |
| Wang, ZY | 1 |
| Liu, J | 6 |
| Aleksic Sabo, V | 1 |
| Knezevic, P | 1 |
| Borges-Argáez, R | 1 |
| Chan-Balan, R | 1 |
| Cetina-Montejo, L | 1 |
| Ayora-Talavera, G | 1 |
| Sansores-Peraza, P | 1 |
| Gómez-Carballo, J | 1 |
| Cáceres-Farfán, M | 1 |
| Jang, J | 1 |
| Akin, D | 1 |
| Bashir, R | 1 |
| Yu, Z | 1 |
| Zhu, J | 2 |
| Jiang, H | 1 |
| He, C | 2 |
| Xiao, Z | 1 |
| Xu, J | 2 |
| Sun, Q | 1 |
| Han, D | 1 |
| Lei, H | 1 |
| Zhao, K | 2 |
| Zhu, L | 1 |
| Li, X | 4 |
| Fu, H | 2 |
| Wilson, BK | 1 |
| Step, DL | 1 |
| Maxwell, CL | 1 |
| Gifford, CA | 1 |
| Richards, CJ | 1 |
| Krehbiel, CR | 1 |
| Warner, JM | 1 |
| Doerr, AJ | 1 |
| Erickson, GE | 1 |
| Guretzky, JA | 1 |
| Rasby, RJ | 1 |
| Watson, AK | 1 |
| Klopfenstein, TJ | 1 |
| Sun, Y | 4 |
| Liu, Z | 3 |
| Pham, TD | 1 |
| Lee, BK | 1 |
| Yang, FC | 1 |
| Wu, KH | 1 |
| Lin, WP | 1 |
| Hu, MK | 1 |
| Lin, L | 3 |
| Shao, J | 1 |
| Sun, M | 2 |
| Xu, G | 1 |
| Zhang, X | 6 |
| Xu, N | 1 |
| Wang, R | 1 |
| Liu, S | 3 |
| He, H | 1 |
| Dong, X | 2 |
| Yang, M | 2 |
| Yang, Q | 1 |
| Duan, S | 1 |
| Yu, Y | 2 |
| Han, J | 2 |
| Zhang, C | 3 |
| Yang, X | 1 |
| Li, W | 3 |
| Wang, T | 2 |
| Campbell, DA | 1 |
| Gao, K | 1 |
| Zager, RA | 1 |
| Johnson, ACM | 1 |
| Guillem, A | 1 |
| Keyser, J | 1 |
| Singh, B | 1 |
| Steubl, D | 1 |
| Schneider, MP | 1 |
| Meiselbach, H | 1 |
| Nadal, J | 1 |
| Schmid, MC | 1 |
| Saritas, T | 1 |
| Krane, V | 1 |
| Sommerer, C | 1 |
| Baid-Agrawal, S | 1 |
| Voelkl, J | 1 |
| Kotsis, F | 1 |
| Köttgen, A | 1 |
| Eckardt, KU | 1 |
| Scherberich, JE | 1 |
| Li, H | 4 |
| Yao, L | 2 |
| Sun, L | 3 |
| Zhu, Z | 2 |
| Naren, N | 1 |
| Zhang, XX | 2 |
| Gentile, GL | 1 |
| Rupert, AS | 1 |
| Carrasco, LI | 1 |
| Garcia, EM | 1 |
| Kumar, NG | 1 |
| Walsh, SW | 1 |
| Jefferson, KK | 1 |
| Guest, RL | 1 |
| Samé Guerra, D | 1 |
| Wissler, M | 1 |
| Grimm, J | 1 |
| Silhavy, TJ | 1 |
| Lee, JH | 2 |
| Yoo, JS | 1 |
| Kim, Y | 1 |
| Kim, JS | 2 |
| Lee, EJ | 1 |
| Roe, JH | 1 |
| Delorme, M | 1 |
| Bouchard, PA | 1 |
| Simon, M | 1 |
| Simard, S | 1 |
| Lellouche, F | 1 |
| D'Urzo, KA | 1 |
| Mok, F | 1 |
| D'Urzo, AD | 1 |
| Koneru, B | 1 |
| Lopez, G | 1 |
| Farooqi, A | 1 |
| Conkrite, KL | 1 |
| Nguyen, TH | 1 |
| Macha, SJ | 1 |
| Modi, A | 1 |
| Rokita, JL | 1 |
| Urias, E | 1 |
| Hindle, A | 1 |
| Davidson, H | 1 |
| Mccoy, K | 1 |
| Nance, J | 1 |
| Yazdani, V | 1 |
| Irwin, MS | 1 |
| Wheeler, DA | 1 |
| Maris, JM | 1 |
| Diskin, SJ | 1 |
| Reynolds, CP | 1 |
| Abhilash, L | 1 |
| Kalliyil, A | 1 |
| Sheeba, V | 1 |
| Hartley, AM | 2 |
| Meunier, B | 2 |
| Pinotsis, N | 1 |
| Maréchal, A | 2 |
| Xu, JY | 1 |
| Genko, N | 1 |
| Haraux, F | 1 |
| Rich, PR | 1 |
| Kamalanathan, M | 1 |
| Doyle, SM | 1 |
| Xu, C | 1 |
| Achberger, AM | 1 |
| Wade, TL | 1 |
| Schwehr, K | 1 |
| Santschi, PH | 1 |
| Sylvan, JB | 1 |
| Quigg, A | 1 |
| Leong, W | 1 |
| Xu, W | 2 |
| Gao, S | 1 |
| Zhai, X | 1 |
| Wang, C | 2 |
| Gilson, E | 1 |
| Ye, J | 1 |
| Lu, Y | 1 |
| Yan, R | 1 |
| Zhang, Y | 6 |
| Hu, Z | 1 |
| You, Q | 1 |
| Cai, Q | 1 |
| Yang, D | 1 |
| Gu, S | 1 |
| Dai, H | 1 |
| Zhao, X | 1 |
| Gui, C | 1 |
| Gui, J | 1 |
| Wu, PK | 1 |
| Hong, SK | 1 |
| Starenki, D | 1 |
| Oshima, K | 1 |
| Shao, H | 1 |
| Gestwicki, JE | 1 |
| Tsai, S | 1 |
| Park, JI | 1 |
| Zhao, R | 1 |
| Gu, Z | 1 |
| Dong, C | 2 |
| Guo, G | 1 |
| Barrett, HE | 1 |
| Meester, EJ | 1 |
| van Gaalen, K | 1 |
| van der Heiden, K | 1 |
| Krenning, BJ | 1 |
| Beekman, FJ | 1 |
| de Blois, E | 1 |
| de Swart, J | 1 |
| Verhagen, HJ | 1 |
| Maina, T | 1 |
| Nock, BA | 1 |
| Norenberg, JP | 1 |
| de Jong, M | 1 |
| Gijsen, FJH | 1 |
| Bernsen, MR | 1 |
| Martínez-Milla, J | 1 |
| Galán-Arriola, C | 1 |
| Carnero, M | 1 |
| Cobiella, J | 1 |
| Pérez-Camargo, D | 1 |
| Bautista-Hernández, V | 1 |
| Rigol, M | 1 |
| Solanes, N | 1 |
| Villena-Gutierrez, R | 1 |
| Lobo, M | 1 |
| Mateo, J | 1 |
| Vilchez-Tschischke, JP | 1 |
| Salinas, B | 1 |
| Cussó, L | 1 |
| López, GJ | 1 |
| Fuster, V | 1 |
| Desco, M | 1 |
| Sanchez-González, J | 1 |
| Ibanez, B | 1 |
| van den Berg, P | 1 |
| Schweitzer, DH | 1 |
| van Haard, PMM | 1 |
| Geusens, PP | 1 |
| van den Bergh, JP | 1 |
| Zhu, X | 1 |
| Huang, X | 2 |
| Yang, G | 2 |
| Lin, Z | 1 |
| Salem, HF | 1 |
| Nafady, MM | 1 |
| Kharshoum, RM | 1 |
| Abd El-Ghafar, OA | 1 |
| Farouk, HO | 1 |
| Domiciano, D | 1 |
| Nery, FC | 1 |
| de Carvalho, PA | 1 |
| Prudente, DO | 1 |
| de Souza, LB | 1 |
| Chalfun-Júnior, A | 1 |
| Paiva, R | 1 |
| Marchiori, PER | 1 |
| Lu, M | 2 |
| An, Z | 1 |
| Jiang, J | 2 |
| Li, J | 9 |
| Du, S | 1 |
| Zhou, H | 1 |
| Cui, J | 1 |
| Wu, W | 2 |
| Liu, Y | 9 |
| Song, J | 1 |
| Lian, Q | 1 |
| Uddin Ahmad, Z | 1 |
| Gang, DD | 1 |
| Konggidinata, MI | 1 |
| Gallo, AA | 1 |
| Zappi, ME | 1 |
| Yang, TWW | 1 |
| Johari, Y | 1 |
| Burton, PR | 1 |
| Earnest, A | 1 |
| Shaw, K | 1 |
| Hare, JL | 1 |
| Brown, WA | 1 |
| Kim, GA | 1 |
| Han, S | 1 |
| Choi, GH | 1 |
| Choi, J | 1 |
| Lim, YS | 1 |
| Gallo, A | 1 |
| Cancelli, C | 1 |
| Ceron, E | 1 |
| Covino, M | 1 |
| Capoluongo, E | 1 |
| Pocino, K | 1 |
| Ianiro, G | 1 |
| Cammarota, G | 1 |
| Gasbarrini, A | 1 |
| Montalto, M | 1 |
| Somasundar, Y | 1 |
| Lu, IC | 1 |
| Mills, MR | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Role of Epithelial Barrier Integrity in Biologic Treatment Response of Severe Asthmatics With/Out Chronic Rhinosinusitis With Nasal Polyps (CRSwNP). Can Shedding of Epithelial Barrier Proteins be Used as Biomarker in Severe Asthma With/Out CRSwNP Manageme[NCT05365841] | 85 participants (Anticipated) | Observational | 2022-05-15 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for histamine and Rhinitis, Allergic
| Article | Year |
|---|---|
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Ebastine in the Treatment of Allergic Rhinitis and Urticaria: 30 Years of Clinical Studies and Real-World Experience.
Topics: Administration, Oral; Butyrophenones; Histamine; Histamine H1 Antagonists; Humans; Piperidines; Rhin | 2020 |
Nasal Hyperreactivity: Nonspecific Nasal Provocation Tests. Review by the Rhinoconjunctivitis Committee of the Spanish Society of Allergy and Clinical Immunology.
Topics: Histamine; Humans; Methacholine Chloride; Nasal Provocation Tests; Rhinitis, Allergic | 2015 |
4 trials available for histamine and Rhinitis, Allergic
| Article | Year |
|---|---|
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Histamine and T helper cytokine-driven epithelial barrier dysfunction in allergic rhinitis.
Topics: Animals; Cell Line; Cytokines; Female; Histamine; Humans; Male; Mice; Mice, Inbred BALB C; Nasal Muc | 2018 |
Inhibitory effect of Phlai capsules on skin test responses among allergic rhinitis patients: a randomized, three-way crossover study.
Topics: Adult; Allergens; Animals; Anti-Allergic Agents; Cross-Over Studies; Double-Blind Method; Histamine; | 2017 |
Variability of histamine pharmacodynamic response in children with allergic rhinitis.
Topics: Adolescent; Anti-Allergic Agents; Area Under Curve; Child; Female; Histamine; Humans; Iontophoresis; | 2013 |
53 other studies available for histamine and Rhinitis, Allergic
| Article | Year |
|---|---|
Astragaloside IV suppresses histamine-induced inflammatory factors and mucin 5 subtype AC overproduction in nasal epithelial cells via regulation of inflammation-related genes.
Topics: Cells, Cultured; Cytokines; Epithelial Cells; Histamine; Histamine Antagonists; Humans; Inflammation | 2021 |
The Protective Role of Cirsilineol against Ovalbumin-Induced Allergic Rhinitis in Mice by Suppression of Inflammation and Oxidative Stress.
Topics: Animals; Anti-Allergic Agents; Biomarkers; Carrier Proteins; Cells, Cultured; Disease Models, Animal | 2021 |
MiR-224 ameliorates inflammation and symptoms in mouse model of allergic rhinitis by targeting CDK9.
Topics: Animals; Cyclin-Dependent Kinase 9; Cytokines; Disease Models, Animal; Histamine; Immunoglobulin E; | 2021 |
The Effects of Combined Therapeutic Protocol on Allergic Rhinitis Symptoms and Molecular Determinants.
Topics: Allergens; Animals; Caspase 1; Fluticasone; Histamine; Immunoglobulin E; Leukotriene C4; Loratadine; | 2022 |
Topics: Allergens; Animals; Cytokines; Disease Models, Animal; Histamine; Mice; Mice, Inbred BALB C; Nasal M | 2022 |
Phosphatidylethanolamine-binding protein 1 (PEBP1) mediates the regulatory role of microRNAs (miRNAs)-205-5p in degranulation and histamine release.
Topics: Animals; beta-N-Acetylhexosaminidases; Cytokines; Histamine; Histamine Release; HMGB1 Protein; Immun | 2022 |
HDAC4 depletion ameliorates IL-13-triggered inflammatory response and mucus production in nasal epithelial cells via activation of SIRT1/NF-κB signaling.
Topics: Epithelial Cells; Histamine; Histone Deacetylases; Humans; Immunoglobulin E; Interleukin-13; Mucus; | 2022 |
Bufotalin ameliorates ovalbumin-induced allergic rhinitis by restoring the Tregs.
Topics: Animals; Cytokines; Disease Models, Animal; Histamine; Immunoglobulin E; Interleukin-10; Mice; Mice, | 2023 |
Bufotalin ameliorates ovalbumin-induced allergic rhinitis by restoring the Tregs.
Topics: Animals; Cytokines; Disease Models, Animal; Histamine; Immunoglobulin E; Interleukin-10; Mice; Mice, | 2023 |
Bufotalin ameliorates ovalbumin-induced allergic rhinitis by restoring the Tregs.
Topics: Animals; Cytokines; Disease Models, Animal; Histamine; Immunoglobulin E; Interleukin-10; Mice; Mice, | 2023 |
Bufotalin ameliorates ovalbumin-induced allergic rhinitis by restoring the Tregs.
Topics: Animals; Cytokines; Disease Models, Animal; Histamine; Immunoglobulin E; Interleukin-10; Mice; Mice, | 2023 |
Effect of Temperature and Humidity on the Allegro-inflammatory Factors and Allergic Rhinitis-related Behavior.
Topics: Animals; Disease Models, Animal; Histamine; Humidity; Immunoglobulin E; Interleukin-4; Leukotriene C | 2022 |
Angiotensin converting enzyme 2 activation improves allergic rhinitis and suppresses Th2 cytokine release.
Topics: Angiotensin-Converting Enzyme 2; Animals; Cytokines; Histamine; Humans; Mice; Rhinitis, Allergic; Th | 2023 |
DPP4 Inhibitor Sitagliptin Reduces Inflammatory Responses and Mast Cell Activation in Allergic Rhinitis.
Topics: Animals; Cytokines; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Anim | 2023 |
Gleditsia sinensis Lam. aqueous extract attenuates nasal inflammation in allergic rhinitis by inhibiting MUC5AC production through suppression of the STAT3/STAT6 pathway.
Topics: Animals; Cytokines; Disease Models, Animal; Gleditsia; Histamine; Humans; Immunoglobulin E; Inflamma | 2023 |
Potential anti-inflammatory effect of Madi-Ryuk and its active ingredient tannic acid on allergic rhinitis.
Topics: Animals; Anti-Inflammatory Agents; Caspase 1; Chemokine CXCL2; Cytokines; Disease Models, Animal; Eo | 2019 |
Tussilagone inhibits allergic responses in OVA-induced allergic rhinitis guinea pigs and IgE-stimulated RBL-2H3 cells.
Topics: Animals; Anti-Allergic Agents; Cell Line; Drugs, Chinese Herbal; Female; Guinea Pigs; Histamine; Imm | 2020 |
Protective effect of Asarum sieboldii essential oil on ovalbumin induced allergic rhinitis in rat.
Topics: Animals; Anti-Allergic Agents; Asarum; Behavior, Animal; Cytokines; Disease Models, Animal; Drugs, C | 2020 |
Neuroinflammatory Gene Expression Pattern Is Similar between Allergic Rhinitis and Atopic Dermatitis but Distinct from Atopic Asthma.
Topics: Adolescent; Asthma; Child; Dermatitis, Atopic; Female; Histamine; Humans; Inflammation; Male; Nerve | 2020 |
Anti-allergic rhinitis activity of α-lipoic acid via balancing Th17/Treg expression and enhancing Nrf2/HO-1 pathway signaling.
Topics: Animals; Cytokines; Down-Regulation; Eosinophils; Epitopes; Goblet Cells; Heme Oxygenase-1; Histamin | 2020 |
Brain activation after nasal histamine provocation in house dust mite allergic rhinitis patients.
Topics: Animals; Brain; Dust; Histamine; Humans; Mites; Nasal Provocation Tests; Pyroglyphidae; Rhinitis, Al | 2021 |
Th2 cells and macrophages cooperatively induce allergic inflammation through histamine signaling.
Topics: Animals; Cells, Cultured; Histamine; Humans; Inflammation; Macrophages; Mice; Mice, Inbred BALB C; R | 2021 |
Th2 cell-derived histamine is involved in nasal Th2 infiltration in mice.
Topics: Allergens; Animals; Cell Movement; Histamine; Histidine Decarboxylase; Mice, Inbred BALB C; Mice, Kn | 2021 |
Exposure of ovalbumin during pregnancy prevents the development of allergic rhinitis in offspring through the induction of mast cell autophagy.
Topics: Allergens; Animals; Autophagy; Disease Models, Animal; Female; Histamine; Humans; Immunity, Maternal | 2021 |
Chitosan-centered nanosystems as sustained therapeutics for allergic rhinitis intervention: Inhibition of histamine-induced cascades.
Topics: Animals; Anti-Allergic Agents; Chitosan; Histamine; Histamine H1 Antagonists; Rats; Rhinitis, Allerg | 2021 |
Yiqi Jiemin decoction alleviates allergic rhinitis in a guinea pig model by suppressing inflammation, restoring Th1/Th2 balance, and improving cellular metabolism.
Topics: Animals; Anti-Inflammatory Agents; Biomarkers; Carrier Proteins; Cytokines; Disease Models, Animal; | 2021 |
Synergistic mucus secretion by histamine and IL-4 through TMEM16A in airway epithelium.
Topics: Adult; Animals; Anoctamin-1; Cells, Cultured; Chloride Channels; Epithelial Cells; Gene Expression R | 2017 |
Anti-inflammatory effect of epigallocatechin gallate in a mouse model of ovalbumin-induced allergic rhinitis.
Topics: Allergens; Animals; Anti-Inflammatory Agents; Catechin; Cyclooxygenase 2; Cytokines; Disease Models, | 2017 |
The potential protective role of taurine against experimental allergic inflammation.
Topics: Animals; Caspase 1; Cell Line; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; | 2017 |
Skullcapflavone II attenuates ovalbumin-induced allergic rhinitis through the blocking of Th2 cytokine production and mast cell histamine release.
Topics: Allergens; Animals; Anti-Inflammatory Agents; Cytokines; Disease Models, Animal; Flavonoids; Histami | 2017 |
Mesenchymal stromal cells ameliorate acute allergic rhinitis in rats.
Topics: Acute Disease; Animals; Cells, Cultured; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; | 2017 |
Chlorpheniramine attenuates histamine-mediated aquaporin 5 downregulation in human nasal epithelial cells via suppression of NF-κB activation.
Topics: Aquaporin 5; Cells, Cultured; Chlorpheniramine; Cyclic AMP Response Element-Binding Protein; Dose-Re | 2017 |
Association of body mass index and season with histamine skin reactivity in Chinese children with allergic rhinitis.
Topics: Body Mass Index; Child; Child, Preschool; Female; Histamine; Humans; Male; Rhinitis, Allergic; Seaso | 2019 |
Geraniol suppresses proinflammatory mediators in phorbol 12-myristate 13-acetate with A23187-induced HMC-1 cells.
Topics: Acyclic Monoterpenes; Animals; Anti-Allergic Agents; Anti-Inflammatory Agents, Non-Steroidal; Calcim | 2018 |
Coptisine Suppresses Mast Cell Degranulation and Ovalbumin-Induced Allergic Rhinitis.
Topics: Animals; Berberine; beta-N-Acetylhexosaminidases; Cell Degranulation; Cell Line; Disease Models, Ani | 2018 |
Genomic and non-genomic effects of glucocorticoids on allergic rhinitis model in mice.
Topics: Adenosine Triphosphate; Animals; Behavior, Animal; Cinnamates; Disease Models, Animal; Estrenes; Fem | 2013 |
[Diagnostic and treatment of allergic rhinitis].
Topics: Age Factors; Basophils; Histamine; Humans; Immunoglobulin E; Rhinitis, Allergic; Rhinitis, Allergic, | 2013 |
Evaluation of the effect of kaempferol in a murine allergic rhinitis model.
Topics: Animals; Anti-Allergic Agents; Caspase 1; Cell Line; Cytokines; Disease Models, Animal; Enzyme Activ | 2013 |
Inhibition of IL-32 and TSLP production through the attenuation of caspase-1 activation in an animal model of allergic rhinitis by Naju Jjok (Polygonum tinctorium).
Topics: Administration, Oral; Animals; Caspase 1; Cell Line; Chemokine CXCL2; Cyclooxygenase 2; Cytokines; D | 2014 |
Stress and anxiety effects on positive skin test responses in young adults with allergic rhinitis.
Topics: Adult; Allergens; Animals; Anxiety; Biomarkers; Cross-Over Studies; Female; Histamine; Humans; Hydro | 2014 |
Allergic rhinitis.
Topics: Allergens; Histamine; Histamine Antagonists; Humans; Immunotherapy; Mast Cells; Nasal Polyps; Preval | 2014 |
Anti-allergic effect of intranasal administration of type-A procyanidin polyphenols based standardized extract of cinnamon bark in ovalbumin sensitized BALB/c mice.
Topics: Administration, Intranasal; Animals; Anti-Allergic Agents; Biflavonoids; Catechin; Cinnamomum zeylan | 2015 |
Bencycloquidium bromide inhibits nasal hypersecretion in a rat model of allergic rhinitis.
Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Cytokines; Disease Models, Animal; Histamine; Male | 2015 |
Antiallergic effect of piperine on ovalbumin-induced allergic rhinitis in mice.
Topics: Acetates; Alkaloids; Animals; Anti-Allergic Agents; Benzodioxoles; Biomarkers; Cell Degranulation; C | 2015 |
Desloratadine citrate disodium injection, a potent histamine H(1) receptor antagonist, inhibits chemokine production in ovalbumin-induced allergic rhinitis guinea pig model and histamine-induced human nasal epithelial cells via inhibiting the ERK1/2 and N
Topics: Animals; Anti-Allergic Agents; Cells, Cultured; Chemokine CCL2; Chemokine CCL5; Chemokines; Disease | 2015 |
The role for human nasal epithelial nuclear factor kappa B activation in histamine-induced mucin 5 subtype B overproduction.
Topics: Adolescent; Adult; Cells, Cultured; Female; Histamine; Humans; Male; Middle Aged; Mucin-5B; Nasal Mu | 2016 |
A novel benzofuran, 4-methoxybenzofuran-5-carboxamide, from Tephrosia purpurea suppressed histamine H1 receptor gene expression through a protein kinase C-δ-dependent signaling pathway.
Topics: Animals; Anti-Allergic Agents; Benzofurans; Cytokines; Disease Models, Animal; Gene Expression Regul | 2016 |
Prostaglandin D2 Modulates Neuronal Excitation of the Trigeminal Ganglion to Augment Allergic Rhinitis in Guinea Pigs.
Topics: Action Potentials; Animals; Behavior, Animal; Electric Stimulation; Guinea Pigs; Histamine; Male; Ne | 2016 |
Allergen endotoxins induce T-cell-dependent and non-IgE-mediated nasal hypersensitivity in mice.
Topics: Allergens; Animals; Endotoxins; Histamine; Immunoglobulin E; Mice, Inbred BALB C; Mice, Knockout; My | 2017 |
2-(4-{2-[(phenylthio)acetyl]carbonohydrazonoyl}phenoxy)acetamide as a new lead compound for management of allergic rhinitis.
Topics: Acetamides; Allergens; Animals; Anti-Allergic Agents; Caspase 1; Cell Line; Cell Survival; Cyclooxyg | 2016 |
Xinqin exhibits the anti-allergic effect through the JAK2/STAT5 signaling pathway.
Topics: Animals; Anti-Allergic Agents; Calcimycin; Cell Degranulation; Cell Line; Disease Models, Animal; Do | 2016 |
Effects of leukotriene D
Topics: Adult; Aged; Airway Resistance; Case-Control Studies; Chronic Disease; Cross-Over Studies; Female; H | 2018 |
Desensitization by histamine (histamine azoprotein) in vertigo, periodic headaches and vasomotor (allergic) rhinitis; review of the literature and report of 102 personal cases.
Topics: Anaphylaxis; Desensitization, Immunologic; Headache; Histamine; Hypersensitivity; Rhinitis; Rhinitis | 1946 |
Bamboo salt reduces allergic responses by modulating the caspase-1 activation in an OVA-induced allergic rhinitis mouse model.
Topics: Animals; Bambusa; Caspase 1; Cell Line; Cytokines; Food Handling; Histamine; Humans; Immunoglobulin | 2012 |
[HISTAMINOPEXY IN ALLERGIC RHINITIS].
Topics: Blood Chemical Analysis; Desensitization, Immunologic; Histamine; Humans; Immunization, Passive; Imm | 1964 |
[The relation between allergic rhinitis and bronchial asthma and the reaction of sensitized tissue to histamine].
Topics: Anti-Allergic Agents; Asthma; Histamine; Histamine Agents; Histamine H1 Antagonists; Humans; Rhiniti | 1954 |