histamine has been researched along with Pemphigoid in 4 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (25.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 2 (50.00) | 29.6817 |
2010's | 1 (25.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Zhang, Y | 1 |
Hwang, BJ | 1 |
Liu, Z | 2 |
Li, N | 1 |
Lough, K | 1 |
Williams, SE | 1 |
Chen, J | 1 |
Burette, SW | 1 |
Diaz, LA | 1 |
Su, MA | 1 |
Xiao, S | 1 |
Dimson, OG | 1 |
Giudice, GJ | 2 |
Fu, CL | 2 |
Van den Bergh, F | 1 |
Warren, SJ | 1 |
Janson, MM | 1 |
Fairley, JA | 2 |
Katayama, I | 1 |
Doi, T | 1 |
Nishioka, K | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
An Open Label Case Series on the Effects of Xolair (Omalizumab) in Bullous Pemphigoid[NCT00472030] | Phase 4 | 2 participants (Actual) | Interventional | 2007-08-31 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
Anti-BP180 IgG levels were completed using an Elisa assay. Anti-BP180 IgG levels were obtained prior to baseline and at week 16 (NCT00472030)
Timeframe: Up to 24 weeks
Intervention | units per milliliter (Number) |
---|---|
Omalizumab Treatment Arm | 92.06 |
(NCT00472030)
Timeframe: Up to 24 weeks
Intervention | units per milliliter (Number) |
---|---|
Omalizumab Treatment Arm | 62.6 |
The subject's eosinophil count measured at baseline was compared to the eosinophil count at week 8. A normal eosinophil count at the University of Iowa Hospital lab is 0-0.4 cells per microliter (NCT00472030)
Timeframe: Baseline, 24 weeks.
Intervention | cells/microliter (Number) |
---|---|
Omalizumab Treatment Arm | 2.16 |
The study subject underwent physical examination and was assessed for cessation of new blister formation via physical examination and photography. (NCT00472030)
Timeframe: Up to 24 weeks
Intervention | weeks (Number) |
---|---|
Omalizumab Treatment Arm | 6 |
Measurement of total body surface area affected by bullous pemphigoid active skin disease(active erosions, blisters, and/or lesions) was measured at Day 0 (prior to treatment with Omalizumab) and at 24 weeks (24 weeks is end of study). (NCT00472030)
Timeframe: Up to 24 weeks
Intervention | percentage of active skin disease (Number) |
---|---|
Omalizumab Treatment Arm | 22.5 |
4 other studies available for histamine and Pemphigoid
Article | Year |
---|---|
BP180 dysfunction triggers spontaneous skin inflammation in mice.
Topics: Adaptive Immunity; Animals; Autoantigens; Collagen Type XVII; Cytokines; Histamine; Humans; Immunogl | 2018 |
Identification of a potential effector function for IgE autoantibodies in the organ-specific autoimmune disease bullous pemphigoid.
Topics: Autoantibodies; Autoantigens; Basophils; Carrier Proteins; Collagen; Collagen Type XVII; Cytoskeleta | 2003 |
Mapping the binding sites of anti-BP180 immunoglobulin E autoantibodies in bullous pemphigoid.
Topics: Antibody Specificity; Autoantibodies; Autoantigens; Basophils; Binding Sites, Antibody; Collagen Typ | 2005 |
High histamine level in the blister fluid of bullous pemphigoid.
Topics: Aged; Eosinophils; Female; Histamine; Humans; Male; Mast Cells; Middle Aged; Pemphigoid, Bullous; Sk | 1984 |