Page last updated: 2024-10-18

histamine and Neuralgia

histamine has been researched along with Neuralgia in 26 studies

Neuralgia: Intense or aching pain that occurs along the course or distribution of a peripheral or cranial nerve.

Research Excerpts

ExcerptRelevanceReference
"Topical lidocaine is effective in postherpetic neuralgia (PHN)."9.11Postherpetic neuralgia: topical lidocaine is effective in nociceptor-deprived skin. ( Baron, R; Binder, A; Kleinert, A; Schattschneider, J; Wasner, G, 2005)
"As there is evidence of a possible immunoregulatory role for H2-histamine receptor antagonists, we carried out a prospective randomized trial to evaluate the in vivo and in vitro effect of cimetidine, an H2-blocker, in the treatment of herpes zoster infection."9.06Cimetidine as an immunomodulator in the treatment of herpes zoster. ( Harel, D; Lahat, N; Laor, A; Miller, A, 1989)
"Histamine was intradermally applied to the diseased dermatome as well as to the corresponding dermatome of the contralateral side of the body."5.30Intracutaneous histamine injection can detect damage of cutaneous afferent fibres in postherpetic neuralgia. ( Altmeyer, P; Hoffmann, K; Hügler, P; Laubenthal, H; Reuther, T; Stücker, M; von Kobyletzki, G, 1997)
"Topical lidocaine is effective in postherpetic neuralgia (PHN)."5.11Postherpetic neuralgia: topical lidocaine is effective in nociceptor-deprived skin. ( Baron, R; Binder, A; Kleinert, A; Schattschneider, J; Wasner, G, 2005)
"As there is evidence of a possible immunoregulatory role for H2-histamine receptor antagonists, we carried out a prospective randomized trial to evaluate the in vivo and in vitro effect of cimetidine, an H2-blocker, in the treatment of herpes zoster infection."5.06Cimetidine as an immunomodulator in the treatment of herpes zoster. ( Harel, D; Lahat, N; Laor, A; Miller, A, 1989)
"Lysophosphatidic acid (LPA) is involved in the pathophysiology of cholestatic pruritus and neuropathic pain."4.12Lysophosphatidic acid activates nociceptors and causes pain or itch depending on the application mode in human skin. ( Düll, MM; Kremer, AE; Namer, B; Reeh, PW; Ries, V; Stengel, M; Strupf, M, 2022)
"The study did not provide any evidence of clinical efficacy for AZD5213 when combined with pregabalin in the treatment of painful diabetic neuropathy."3.01A 3-way Cross-over Study of Pregabalin, Placebo, and the Histamine 3 Receptor Inverse Agonist AZD5213 in Combination With Pregabalin in Patients With Painful Diabetic Neuropathy and Good Pain-reporting Ability. ( Alexander, RC; Katz, N; Raudibaugh, K; Spierings, ELH, 2021)
"Allergic conjunctivitis is highly prevalent and affects up to one third of the general population."2.82Neuropathic pain and itch: mechanisms in allergic conjunctivitis. ( Chisolm, S; Kalangara, JP; Kuruvilla, ME; Vanijcharoenkarn, K, 2022)
"In the current management of neuropathic pain, in addition to antidepressants and anticonvulsants, the use of opioids is wide, despite their related and well-known issues."2.44Ultramicronized ( Bartolucci, G; Ciampi, C; Di Cesare Mannelli, L; Ferrara, V; Ghelardini, C; Lucarini, E; Micheli, L; Nobili, S; Pallecchi, M; Toti, A, 2024)
"To clarify the pathobiology of neuropathic pain, we studied the contribution of neuroinflammation and oxidative stress in a model of peripheral neuropathy."1.46Histamine H ( Durante, M; Galeotti, N; Ghelardini, C; Lucarini, L; Masini, E; Sanna, MD, 2017)
"Ongoing neuropathic pain and its attenuation by histamine was assessed using conditioned place-preference test."1.43Spinal histamine in attenuation of mechanical hypersensitivity in the spinal nerve ligation-induced model of experimental neuropathy. ( Pertovaara, A; Viisanen, H; Wei, H; You, HJ, 2016)
"Central neuropathic pain following lesions within the CNS, such as spinal cord injury, is one of the most excruciating types of chronic pain and one of the most difficult to treat."1.35Residual spinothalamic tract pathways predict development of central pain after spinal cord injury. ( Engel, S; Lee, BB; McLachlan, E; Wasner, G, 2008)
"Histamine application was not clearly associated with itch."1.35Response of human oral mucosa and skin to histamine provocation: laser Doppler perfusion imaging discloses differences in the nociceptive nervous system. ( Bay, B; Hilliges, M; Sandborgh-Englund, G; Weidner, C, 2009)
"Histamine was intradermally applied to the diseased dermatome as well as to the corresponding dermatome of the contralateral side of the body."1.30Intracutaneous histamine injection can detect damage of cutaneous afferent fibres in postherpetic neuralgia. ( Altmeyer, P; Hoffmann, K; Hügler, P; Laubenthal, H; Reuther, T; Stücker, M; von Kobyletzki, G, 1997)

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19903 (11.54)18.7374
1990's4 (15.38)18.2507
2000's4 (15.38)29.6817
2010's8 (30.77)24.3611
2020's7 (26.92)2.80

Authors

AuthorsStudies
Røikjer, J1
Croosu, SS1
Hansen, TM1
Frøkjær, JB1
Andersen, HH1
Arendt-Nielsen, L1
Mørch, CD1
Ejskjaer, N1
Kalangara, JP1
Vanijcharoenkarn, K1
Chisolm, S1
Kuruvilla, ME1
Micheli, L3
Lucarini, E3
Nobili, S3
Bartolucci, G3
Pallecchi, M3
Toti, A3
Ferrara, V3
Ciampi, C3
Ghelardini, C4
Di Cesare Mannelli, L3
Sanna, MD2
Borgonetti, V1
Masini, E2
Galeotti, N2
Alexander, RC1
Raudibaugh, K1
Spierings, ELH1
Katz, N1
Düll, MM1
Stengel, M1
Ries, V1
Strupf, M1
Reeh, PW1
Kremer, AE1
Namer, B1
Kaur, G1
Singh, N1
Jaggi, AS1
Schneider, EH1
Obara, I2
Telezhkin, V1
Alrashdi, I1
Chazot, PL2
Yu, J1
Lou, GD1
Yue, JX1
Tang, YY1
Hou, WW1
Shou, WT1
Ohtsu, H1
Zhang, SH1
Chen, Z1
Wei, H2
Jin, CY1
Viisanen, H2
You, HJ2
Pertovaara, A2
Medrano, MC1
Signoret-Genest, J1
Jiménez-Díaz, L1
Géranton, SM1
Hunt, SP1
Lucarini, L1
Durante, M1
Wasner, G2
Lee, BB1
Engel, S1
McLachlan, E1
Bay, B1
Hilliges, M1
Weidner, C1
Sandborgh-Englund, G1
Tiligada, E1
Kyriakidis, K1
Passani, MB1
STEELMAN, HF1
Kleinert, A1
Binder, A1
Schattschneider, J1
Baron, R3
Saguer, M2
Stücker, M1
Hügler, P1
von Kobyletzki, G1
Reuther, T1
Hoffmann, K1
Laubenthal, H1
Altmeyer, P1
Kashiba, H1
Senba, E1
Benarroch, EE1
Low, PA1
Miller, A1
Harel, D1
Laor, A1
Lahat, N1
Lance, JW1
Anthony, M1

Reviews

5 reviews available for histamine and Neuralgia

ArticleYear
Neuropathic pain and itch: mechanisms in allergic conjunctivitis.
    Current opinion in allergy and clinical immunology, 2022, 10-01, Volume: 22, Issue:5

    Topics: Conjunctiva; Conjunctivitis, Allergic; Histamine; Humans; Inflammation; Neuralgia; Pruritus

2022
Mast cells in neuropathic pain: an increasing spectrum of their involvement in pathophysiology.
    Reviews in the neurosciences, 2017, 10-26, Volume: 28, Issue:7

    Topics: Animals; Cell Degranulation; Histamine; Humans; Mast Cells; Neuralgia; p-Methoxy-N-methylphenethylam

2017
Histamine, histamine receptors, and neuropathic pain relief.
    British journal of pharmacology, 2020, Volume: 177, Issue:3

    Topics: Analgesics; Histamine; Humans; Neuralgia; Pain Management; Receptors, Histamine

2020
Histamine pharmacology and new CNS drug targets.
    CNS neuroscience & therapeutics, 2011, Volume: 17, Issue:6

    Topics: Animals; Brain; Brain Chemistry; Central Nervous System Agents; Cognition Disorders; Histamine; Hist

2011
[Primary sensory neurons expressing histamine H1-receptor mRNA].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2001, Volume: 118, Issue:1

    Topics: Animals; Capsaicin; Gene Expression; Histamine; Humans; Neuralgia; Neurons, Afferent; Neuropeptides;

2001

Trials

3 trials available for histamine and Neuralgia

ArticleYear
A 3-way Cross-over Study of Pregabalin, Placebo, and the Histamine 3 Receptor Inverse Agonist AZD5213 in Combination With Pregabalin in Patients With Painful Diabetic Neuropathy and Good Pain-reporting Ability.
    The Clinical journal of pain, 2021, Volume: 37, Issue:1

    Topics: Analgesics; Cross-Over Studies; Diabetes Mellitus; Diabetic Neuropathies; gamma-Aminobutyric Acid; H

2021
Postherpetic neuralgia: topical lidocaine is effective in nociceptor-deprived skin.
    Journal of neurology, 2005, Volume: 252, Issue:6

    Topics: Administration, Cutaneous; Aged; Aged, 80 and over; Anesthetics, Local; Double-Blind Method; Female;

2005
Cimetidine as an immunomodulator in the treatment of herpes zoster.
    Journal of neuroimmunology, 1989, Volume: 22, Issue:1

    Topics: Adjuvants, Immunologic; Cells, Cultured; Cimetidine; Herpes Zoster; Histamine; Humans; Lymphocyte Ac

1989

Other Studies

18 other studies available for histamine and Neuralgia

ArticleYear
The Histamine-Induced Axon-Reflex Response in People With Type 1 Diabetes With and Without Peripheral Neuropathy and Pain: A Clinical, Observational Study.
    The journal of pain, 2022, Volume: 23, Issue:7

    Topics: Adult; Axons; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Histamine; Humans; Neuralgia; Reflex

2022
Ultramicronized
    Current neuropharmacology, 2024, Volume: 22, Issue:1

    Topics: Analgesics, Opioid; Animals; Histamine; Mast Cells; Morphine; Neuralgia; Neuroglia; Rats

2024
Ultramicronized
    Current neuropharmacology, 2024, Volume: 22, Issue:1

    Topics: Analgesics, Opioid; Animals; Histamine; Mast Cells; Morphine; Neuralgia; Neuroglia; Rats

2024
Ultramicronized
    Current neuropharmacology, 2024, Volume: 22, Issue:1

    Topics: Analgesics, Opioid; Animals; Histamine; Mast Cells; Morphine; Neuralgia; Neuroglia; Rats

2024
Ultramicronized
    Current neuropharmacology, 2024, Volume: 22, Issue:1

    Topics: Analgesics, Opioid; Animals; Histamine; Mast Cells; Morphine; Neuralgia; Neuroglia; Rats

2024
Histamine H
    European journal of pharmacology, 2020, Feb-05, Volume: 868

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic Neurons; Animals; Benzimidazoles; Clonidine; Diseas

2020
Lysophosphatidic acid activates nociceptors and causes pain or itch depending on the application mode in human skin.
    Pain, 2022, 03-01, Volume: 163, Issue:3

    Topics: Animals; Histamine; Humans; Lysophospholipids; Nerve Fibers, Unmyelinated; Neuralgia; Nociceptors; P

2022
New perspectives for a well-known biogenic amine: mast cell-derived histamine as pathophysiological agent in vincristine-induced neuropathic pain.
    Naunyn-Schmiedeberg's archives of pharmacology, 2017, Volume: 390, Issue:11

    Topics: Biogenic Amines; Histamine; Mast Cells; Neuralgia; Vincristine

2017
Effects of histamine on spontaneous neuropathic pain induced by peripheral axotomy.
    Neuroscience bulletin, 2013, Volume: 29, Issue:3

    Topics: Analgesics; Animals; Axotomy; Behavior, Animal; Histamine; Male; Mice; Neuralgia; Neuroma; Pain Thre

2013
Histamine in the locus coeruleus promotes descending noradrenergic inhibition of neuropathic hypersensitivity.
    Pharmacological research, 2014, Volume: 90

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic Neurons; A

2014
Inhibition of the mammalian target of rapamycin complex 1 signaling pathway reduces itch behaviour in mice.
    Pain, 2015, Volume: 156, Issue:8

    Topics: Animals; Disease Models, Animal; Gastrin-Releasing Peptide; Histamine; Hypoglycemic Agents; Male; Me

2015
Spinal histamine in attenuation of mechanical hypersensitivity in the spinal nerve ligation-induced model of experimental neuropathy.
    European journal of pharmacology, 2016, Feb-05, Volume: 772

    Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Histamine; Hyperalgesia; Ligation

2016
Histamine H
    British journal of pharmacology, 2017, Volume: 174, Issue:1

    Topics: Animals; Dose-Response Relationship, Drug; Guanidines; Histamine; Inflammation; Male; Mice; Neuralgi

2017
Residual spinothalamic tract pathways predict development of central pain after spinal cord injury.
    Brain : a journal of neurology, 2008, Volume: 131, Issue:Pt 9

    Topics: Adult; Capsaicin; Cold Temperature; Female; Histamine; Hot Temperature; Humans; Male; Menthol; Middl

2008
Response of human oral mucosa and skin to histamine provocation: laser Doppler perfusion imaging discloses differences in the nociceptive nervous system.
    Acta odontologica Scandinavica, 2009, Volume: 67, Issue:2

    Topics: Adult; Analysis of Variance; Axons; Burning Mouth Syndrome; Case-Control Studies; Chronic Disease; F

2009
HEADACHE, ITS CAUSES AND TREATMENT.
    Arizona medicine, 1964, Volume: 21

    Topics: Brain Neoplasms; Drug Therapy; Facial Neuralgia; Headache; Hematoma; Hematoma, Subdural; Histamine;

1964
Axon-reflex reactions in affected and homologous contralateral skin after unilateral peripheral injury of thoracic segmental nerves in humans.
    Neuroscience letters, 1994, Jan-03, Volume: 165, Issue:1-2

    Topics: Aged; Electric Stimulation; Female; Herpes Zoster; Histamine; Humans; Injections, Intradermal; Male;

1994
Postherpetic neuralgia. Are C-nociceptors involved in signalling and maintenance of tactile allodynia?
    Brain : a journal of neurology, 1993, Volume: 116 ( Pt 6)

    Topics: Aged; Body Temperature; Female; Herpes Zoster; Histamine; Humans; Iontophoresis; Male; Middle Aged;

1993
Intracutaneous histamine injection can detect damage of cutaneous afferent fibres in postherpetic neuralgia.
    Dermatology (Basel, Switzerland), 1997, Volume: 195, Issue:4

    Topics: Aged; Axons; Diagnosis, Differential; Female; Herpes Zoster; Histamine; Humans; Hyperemia; Injection

1997
The acetylcholine-induced flare response in evaluation of small fiber dysfunction.
    Annals of neurology, 1991, Volume: 29, Issue:6

    Topics: Acetylcholine; Adult; Afferent Pathways; Autonomic Fibers, Postganglionic; Diabetic Neuropathies; Do

1991
Migrainous neuralgia or cluster headache?
    Journal of the neurological sciences, 1971, Volume: 13, Issue:4

    Topics: Adolescent; Adult; Age Factors; Aged; Carbamazepine; Cerebral Arteries; Child; Diagnosis, Differenti

1971