Page last updated: 2024-10-18

histamine and Nasal Polyps

histamine has been researched along with Nasal Polyps in 31 studies

Nasal Polyps: Focal accumulations of EDEMA fluid in the NASAL MUCOSA accompanied by HYPERPLASIA of the associated submucosal connective tissue. Polyps may be NEOPLASMS, foci of INFLAMMATION, degenerative lesions, or malformations.

Research Excerpts

ExcerptRelevanceReference
"To study the effects of dexamethasone and histamine on the expression of MUC5AC mRNA and protein in human nasal polyps."9.12[Effects of glucocorticoid and histamine on MUC5AC mRNA and protein expression in human nasal polyps]. ( Jin, S; Long, X; Peng, L; Zhang, H; Zhen, H, 2007)
"We attempted to determine the relationship of nasal polyps to histamine (HA) metabolism."7.68Histamine metabolism in nasal polyps. ( Abe, Y; Fukui, H; Harada, T; Imamura, I; Irifune, M; Matsunaga, T; Ogino, S, 1993)
"Histamine, norepinephrine and serotonin were assayed and localized by fluorescence histochemistry in normal mucosa and nasal polyps because of their possible role in the development of inflammation and edema."7.66Histamine, norepinephrine and serotonin content of nasal polyps. ( Brody, MJ; Bumsted, RM; El-Ackad, T; Smith, JM, 1979)
"We attempted to determine the relationship of nasal polyps to histamine (HA) metabolism."3.68Histamine metabolism in nasal polyps. ( Abe, Y; Fukui, H; Harada, T; Imamura, I; Irifune, M; Matsunaga, T; Ogino, S, 1993)
" There was no significant difference between the polyp histamine levels in patients with a history of asthma, aspirin hypersensitivity, hay fever and positive skin tests."3.67Free histamine in nasal polyp fluid. ( Bickerton, R; Drake-Lee, AB; McLaughlan, P, 1984)
" For this purpose, 20 patients were tested for antigen-induced histamine release from biopsies of nasal mucosa and nasal polyps."3.66Antigen induced histamine release from mucosa in nasal polyposis. ( Baenkler, HW; Behnsen, H; Schaubschläger, W, 1983)
"Histamine, norepinephrine and serotonin were assayed and localized by fluorescence histochemistry in normal mucosa and nasal polyps because of their possible role in the development of inflammation and edema."3.66Histamine, norepinephrine and serotonin content of nasal polyps. ( Brody, MJ; Bumsted, RM; El-Ackad, T; Smith, JM, 1979)
"Histamine is the main cause of sneezing and hypersecretion, while other mediators probably also play a role in nasal blockage."1.40Allergic rhinitis. ( Mygind, N, 2014)
"Nasal polyps are a condition of uncertain aetiology but are associated with diseases of the lower respiratory tract, in particular, asthma and cystic fibrosis."1.27The release of histamine from nasal polyp tissue and peripheral blood when challenged with antihuman IgE, house dust mite extract and mixed grass pollen extract and compared with positive skin tests. ( Drake-Lee, AB; McLoughlan, P, 1988)
"Histamine release was significantly increased upon anti-IgE in polyposis only."1.27In vitro histamine release from nasal mucosa upon bacterial antigens. ( Baenkler, HW; Dechant, F; Hosemann, W, 1987)

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-199019 (61.29)18.7374
1990's7 (22.58)18.2507
2000's4 (12.90)29.6817
2010's1 (3.23)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mygind, N2
BAXTER, JD1
ROSE, B1
SATO, S1
FRANKLAND, AW1
Jókúti, A2
Schwelberger, H1
Darvas, Z2
Páli, Z1
Bösze, S1
Falus, A2
Hirschberg, A2
Hellinger, E1
Hellinger, A1
Thurmond, RL1
Peng, L1
Zhen, H1
Long, X1
Zhang, H1
Jin, S1
Drake-Lee, AB6
McLaughlan, P3
Baker, TH1
Fal, W1
Ziemski, Z1
Branska, B1
Galary, E1
Baenkler, HW2
Schaubschläger, W1
Behnsen, H1
Bickerton, R1
Finotto, S2
Dolovich, J2
Denburg, JA3
Jordana, M2
Marshall, JS2
Vignola, AM1
Crampette, L1
Mondain, M1
Sauvère, G1
Czarlewski, W1
Bousquet, J1
Campbell, AM1
Ogino, S2
Abe, Y2
Irifune, M2
Harada, T1
Matsunaga, T2
Imamura, I2
Fukui, H2
Wada, H1
Butterfield, JH1
Slater, A1
Smallman, LA1
Logan, AC1
Di Lorenzo, G1
Drago, A1
Esposito Pellitteri, M1
Candore, G1
Colombo, A1
Gervasi, F1
Pacor, ML1
Purello D'Ambrosio, F1
Caruso, C1
Austen, KF1
Orange, RP1
Bumsted, RM1
El-Ackad, T1
Smith, JM1
Brody, MJ1
Dziedziczko, A1
Pawlik, K1
Ohtoshi, T1
Tsuda, T1
Vancheri, C1
Abrams, JS1
Gauldie, J1
McLoughlan, P1
Dechant, F1
Hosemann, W1
Bykova, VP1
Khrushchova, VM1
Prokop'eva, ZP1
Kirienko, GM1
Mostafa, HM1
Abdel-Latif, SM1
el-Din, SB1
Samter, M2
Beers, RF2

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Reproducibility of Cell Counts in Nasal Lavage: A Comparison of Pooled Versus Non-Pooled Nasal Lavage Samples[NCT00229190]21 participants Interventional2004-09-30Completed
A Double-blind,Placebo-controlled, Randomized, Crossover Trial of Mint Tea High in Rosmarinic Acid in Adults With Nasal Polyposis[NCT00465543]Phase 222 participants (Actual)Interventional2007-05-31Completed
Challenge Test for Acetylsalicylic Acid Hypersensitivity[NCT01681615]50 participants (Anticipated)Interventional2012-09-30Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for histamine and Nasal Polyps

ArticleYear
ADVANCES IN ALLERGY.
    The Practitioner, 1963, Volume: 191

    Topics: Antigen-Antibody Reactions; Asthma; Desensitization, Immunologic; Eosinophilia; Histamine; Humans; H

1963
Clinical investigation of allergic rhinitis and allied conditions.
    Allergy, 1979, Volume: 34, Issue:4

    Topics: Allergens; Environment; Eosinophils; Food Hypersensitivity; Histamine; Humans; Immunoglobulin E; Met

1979

Trials

1 trial available for histamine and Nasal Polyps

ArticleYear
[Effects of glucocorticoid and histamine on MUC5AC mRNA and protein expression in human nasal polyps].
    Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery, 2007, Volume: 21, Issue:20

    Topics: Adolescent; Adult; Dexamethasone; Female; Glucocorticoids; Histamine; Humans; Male; Middle Aged; Muc

2007

Other Studies

28 other studies available for histamine and Nasal Polyps

ArticleYear
Allergic rhinitis.
    Chemical immunology and allergy, 2014, Volume: 100

    Topics: Allergens; Histamine; Histamine Antagonists; Humans; Immunotherapy; Mast Cells; Nasal Polyps; Preval

2014
The histamine content of allergic and nonallergic human nasal mucous membrane with simultaneous observations on the eosinophils.
    The Journal of allergy, 1953, Volume: 24, Issue:1

    Topics: Eosinophils; Histamine; Humans; Hypersensitivity; Leukocyte Count; Mucous Membrane; Nasal Mucosa; Na

1953
[The histopathological studies on the experimental rhinosinuitis].
    Nihon Jibiinkoka Gakkai kaiho, 1963, Volume: 66

    Topics: Cortisone; Desoxycorticosterone; Histamine; Humans; Hyaluronoglucosaminidase; Nasal Mucosa; Nasal Po

1963
Histamine metabolism is altered in nasal polyposis.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2004, Volume: 53 Suppl 1

    Topics: Chromatography, High Pressure Liquid; Histamine; Histamine N-Methyltransferase; Histidine Decarboxyl

2004
Histamine H4 receptor expression is elevated in human nasal polyp tissue.
    Cell biology international, 2007, Volume: 31, Issue:11

    Topics: Eosinophil Cationic Protein; Eosinophils; Histamine; Humans; Nasal Polyps; Receptors, G-Protein-Coup

2007
Histamine, asthma, and nasal polyps.
    Lancet (London, England), 1982, Jul-24, Volume: 2, Issue:8291

    Topics: Asthma; Histamine; Humans; Immunoglobulin E; Mast Cells; Nasal Polyps

1982
Clinical symptoms, free histamine and IgE in patients with nasal polyposis.
    International archives of allergy and applied immunology, 1982, Volume: 69, Issue:3

    Topics: Amine Oxidase (Copper-Containing); Complement Activation; Histamine; Histamine Release; Humans; Hype

1982
[Histamine in the basophils in various upper respiratory diseases of allergic etiology].
    Otolaryngologia polska = The Polish otolaryngology, 1983, Volume: 37, Issue:1

    Topics: Adenoids; Adolescent; Adult; Basophils; Child; Child, Preschool; Chronic Disease; Female; Histamine;

1983
Antigen induced histamine release from mucosa in nasal polyposis.
    Clinical otolaryngology and allied sciences, 1983, Volume: 8, Issue:4

    Topics: Adolescent; Adult; Antigens, Bacterial; Histamine; Histamine Release; Humans; Hypersensitivity, Imme

1983
Histamine and its release from nasal polyps: preliminary communication.
    Journal of the Royal Society of Medicine, 1984, Volume: 77, Issue:2

    Topics: Female; Histamine; Histamine Release; Humans; Hypersensitivity; Male; Mast Cells; Microscopy, Electr

1984
Free histamine in nasal polyp fluid.
    Rhinology, 1984, Volume: 22, Issue:2

    Topics: Aspirin; Asthma; Drug Hypersensitivity; Extracellular Space; Histamine; Humans; Hypersensitivity; Na

1984
Functional heterogeneity of mast cells isolated from different microenvironments within nasal polyp tissue.
    Clinical and experimental immunology, 1994, Volume: 95, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Calcimycin; Cell Separation; Edetic Acid; Female; Histamine; Histami

1994
Functional heterogeneity of mast cells isolated from different microenvironments within nasal polyp tissue.
    Clinical and experimental immunology, 1994, Volume: 95, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Calcimycin; Cell Separation; Edetic Acid; Female; Histamine; Histami

1994
Functional heterogeneity of mast cells isolated from different microenvironments within nasal polyp tissue.
    Clinical and experimental immunology, 1994, Volume: 95, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Calcimycin; Cell Separation; Edetic Acid; Female; Histamine; Histami

1994
Functional heterogeneity of mast cells isolated from different microenvironments within nasal polyp tissue.
    Clinical and experimental immunology, 1994, Volume: 95, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Calcimycin; Cell Separation; Edetic Acid; Female; Histamine; Histami

1994
Inhibitory activity of loratadine and descarboethoxyloratadine on expression of ICAM-1 and HLA-DR by nasal epithelial cells.
    Allergy, 1995, Volume: 50, Issue:3

    Topics: Adult; Histamine; Histamine H1 Antagonists; HLA-DR Antigens; Humans; In Vitro Techniques; Intercellu

1995
Histamine metabolism in nasal polyps.
    The Annals of otology, rhinology, and laryngology, 1993, Volume: 102, Issue:2

    Topics: Amine Oxidase (Copper-Containing); Aspirin; Asthma; Bronchial Provocation Tests; Histamine; Histamin

1993
Histamine content, synthesis and degradation in human nasal mucosa.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1993, Volume: 23, Issue:2

    Topics: Adolescent; Adult; Amine Oxidase (Copper-Containing); Chromatography, High Pressure Liquid; Female;

1993
Specific inhibition of beta-tryptase expression in a human mast cell line by granulocyte-macrophage colony-stimulating factor produced by airways structural cells.
    American journal of respiratory cell and molecular biology, 1996, Volume: 15, Issue:3

    Topics: Blotting, Northern; Cell Division; Chymases; Culture Media, Conditioned; Endopeptidases; Fibroblasts

1996
Mucociliary function in patients with nasal polyps.
    Clinical otolaryngology and allied sciences, 1996, Volume: 21, Issue:4

    Topics: Cilia; Culture Techniques; Dose-Response Relationship, Drug; Epithelium; Histamine; Humans; Mucocili

1996
Measurement of inflammatory mediators of mast cells and eosinophils in native nasal lavage fluid in nasal polyposis.
    International archives of allergy and immunology, 2001, Volume: 125, Issue:2

    Topics: Adolescent; Adult; Animals; Blood Proteins; Body Fluids; Eosinophil Granule Proteins; Eosinophilia;

2001
Bronchial asthma: the possible role of the chemical mediators of immediate hypersensitivity in the pathogenesis of subacute chronic disease.
    The American review of respiratory disease, 1975, Volume: 112, Issue:3

    Topics: Acetylcholine; Adrenergic beta-Agonists; Anaphylaxis; Asthma; Autacoids; Blood Coagulation Factors;

1975
Histamine, norepinephrine and serotonin content of nasal polyps.
    The Laryngoscope, 1979, Volume: 89, Issue:5 Pt 1

    Topics: Adolescent; Adult; Aged; Amines; Child; Female; Histamine; Humans; Male; Mast Cells; Middle Aged; Na

1979
[Total blood serum IgE level and bronchial reactivity to non-specific exercise and histamine tests in allergic and non-allergic respiratory diseases].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1979, Dec-10, Volume: 34, Issue:50

    Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Bronchi; Bronchial Provocation Tests; Child; Fe

1979
Human upper airway epithelial cell-derived granulocyte-macrophage colony-stimulating factor induces histamine-containing cell differentiation of human progenitor cells.
    International archives of allergy and applied immunology, 1991, Volume: 95, Issue:4

    Topics: Antibodies, Monoclonal; Butyrates; Butyric Acid; Cell Differentiation; Cell Line; Cells, Cultured; C

1991
The release of histamine from nasal polyp tissue and peripheral blood when challenged with antihuman IgE, house dust mite extract and mixed grass pollen extract and compared with positive skin tests.
    The Journal of laryngology and otology, 1988, Volume: 102, Issue:10

    Topics: Animals; Dust; Female; Histamine; Humans; Hypersensitivity, Immediate; Immunoglobulin E; Male; Mites

1988
In vitro histamine release from nasal mucosa upon bacterial antigens.
    Rhinology, 1987, Volume: 25, Issue:1

    Topics: Antigens, Bacterial; Histamine; Humans; Immunoglobulin E; Nasal Mucosa; Nasal Polyps; Nose Neoplasms

1987
[Correlation between histamine levels and phases of serous inflammation in chronic rhinosinusitis].
    Biulleten' eksperimental'noi biologii i meditsiny, 1973, Volume: 75, Issue:4

    Topics: Biogenic Amines; Chronic Disease; Eosinophils; Fluorometry; Glycosaminoglycans; Histamine; Histocyto

1973
The transpalatal approach for Vidian neurectomy in allergic rhinitis.
    The Journal of laryngology and otology, 1973, Volume: 87, Issue:8

    Topics: Adolescent; Adult; Denervation; Female; Histamine; Humans; Male; Methods; Middle Aged; Nasal Mucosa;

1973
Concerning the nature of intolerance to aspirin.
    The Journal of allergy, 1967, Volume: 40, Issue:5

    Topics: Aminopyrine; Antipyrine; Aspirin; Asthma; Chemoreceptor Cells; Drug Hypersensitivity; Edema; Histami

1967
Intolerance to aspirin. Clinical studies and consideration of its pathogenesis.
    Annals of internal medicine, 1968, Volume: 68, Issue:5

    Topics: Adult; Age Factors; Allergens; Angioedema; Aspirin; Asthma; Chemical Phenomena; Chemistry; Drug Hype

1968