histamine has been researched along with Nasal Obstruction in 28 studies
Nasal Obstruction: Any hindrance to the passage of air into and out of the nose. The obstruction may be unilateral or bilateral, and may involve any part of the NASAL CAVITY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of this study was to characterize the late phase nasal obstruction that is induced by a nasal histamine challenge in sensitized guinea pigs." | 7.74 | Histamine induces nasal obstruction via calcitonin gene-related peptide in sensitized guinea pigs. ( Imamura, S; Kase, Y; Majima, Y; Sakaguchi, M; Sakakura, Y; Takeda, S; Ukai, K; Yamamoto, M; Yuzurihar, M, 2007) |
| "Recently it has been shown that patients with atopic rhinitis and with an allergy to house dust mites have a stronger nasal response to insufflation of histamine, methacholine and phentolamine than a control group." | 7.68 | Nasal hyper-responsiveness to histamine, methacholine and phentolamine in patients with perennial non-allergic rhinitis and in patients with infectious rhinitis. ( Dieges, PH; Gerth van Wijk, R, 1991) |
| "The purpose of this study was to characterize the late phase nasal obstruction that is induced by a nasal histamine challenge in sensitized guinea pigs." | 3.74 | Histamine induces nasal obstruction via calcitonin gene-related peptide in sensitized guinea pigs. ( Imamura, S; Kase, Y; Majima, Y; Sakaguchi, M; Sakakura, Y; Takeda, S; Ukai, K; Yamamoto, M; Yuzurihar, M, 2007) |
| "We investigated the effects of the thromboxane (TX) A2 antagonist seratrodast, the peptide leukotriene (p-LT) antagonist pranlukast, the antihistaminic drug terfenadine and the glucocorticoid dexamethasone on antigen-induced sneezing, biphasic nasal blockage and nasal hyperresponsiveness to histamine using a guinea pig model of allergic rhinitis." | 3.71 | Involvement of thromboxane A2 and peptide leukotrienes in early and late phase nasal blockage in a guinea pig model of allergic rhinitis. ( Ashida, Y; Kohno, S; Matsumoto, T; Mizutani, N; Nabe, T; Sasaki, K; Yamasaki, M, 2001) |
| ") given 12 h before the final antigen challenge selectively prevented the antigen-induced eosinophilia in blood and the nasal airway, and suppressed the corresponding decrease in the number of cells in bone marrow; however, it failed to inhibit the immediate development of sneezing, early and late nasal blockage responses, goblet cell degranulation and nasal hyperresponsiveness to histamine." | 3.71 | No involvement of interleukin-5 or eosinophils in experimental allergic rhinitis in guinea pigs. ( Kohno, S; Mizutani, N; Nabe, T; Sasaki, K; Yamasaki, M, 2002) |
| " We evaluated the effects of the oral treatment with antigen on: 1) sneezing frequency, 2) nasal blockage after antigen challenge, 3) nasal hyperresponsiveness to histamine and leukotriene D4, and 4) titres of anaphylactic antibodies." | 3.71 | Effect of oral antigen administration on nasal blockage in experimental allergic rhinitis in guinea pigs. ( Kohno, S; Mizutani, N; Nabe, T; Takenaka, H; Terada, T, 2002) |
| "Recently it has been shown that patients with atopic rhinitis and with an allergy to house dust mites have a stronger nasal response to insufflation of histamine, methacholine and phentolamine than a control group." | 3.68 | Nasal hyper-responsiveness to histamine, methacholine and phentolamine in patients with perennial non-allergic rhinitis and in patients with infectious rhinitis. ( Dieges, PH; Gerth van Wijk, R, 1991) |
| "Pretreatment with cetirizine blocked the histamine-induced change in nasal patency as measured by both methods." | 2.67 | Acoustic rhinometry compared with posterior rhinomanometry in the measurement of histamine- and bradykinin-induced changes in nasal airway patency. ( Austin, CE; Foreman, JC, 1994) |
| "In contrast, unilateral nasal obstruction presented in 82% during the late phase, whereas total nasal obstruction was present only in 41%." | 1.29 | Concentrations of chemical mediators in nasal secretions after nasal allergen challenges in atopic patients. ( Clement, P; Derde, MP; Smitz, J; Wang, D, 1995) |
| "Histamine/diphosphate was sprayed into both nostrils every three minutes in doubling concentrations (0." | 1.29 | Modified method of nonspecific nasal provocation with histamine for routine use. ( Godnic-Cvar, J; Plavec, D; Somogyi-Zalud, E, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 18 (64.29) | 18.2507 |
| 2000's | 9 (32.14) | 29.6817 |
| 2010's | 1 (3.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kajiwara, D | 1 |
| Aoyagi, H | 1 |
| Shigeno, K | 1 |
| Togawa, M | 1 |
| Tanaka, K | 1 |
| Inagaki, N | 1 |
| Miyoshi, K | 1 |
| Tiniakov, RL | 1 |
| Tiniakova, OP | 1 |
| McLeod, RL | 1 |
| Hey, JA | 1 |
| Yeates, DB | 2 |
| Fukuda, S | 1 |
| Midoro, K | 1 |
| Gyoten, M | 1 |
| Kawano, Y | 1 |
| Ashida, Y | 2 |
| Nabe, T | 4 |
| Kohno, S | 4 |
| Nagaya, H | 1 |
| Skorohod, N | 1 |
| Taylor-Clark, T | 1 |
| Sodha, R | 1 |
| Warner, B | 1 |
| Foreman, J | 1 |
| Sakaguchi, M | 1 |
| Imamura, S | 1 |
| Yamamoto, M | 1 |
| Yuzurihar, M | 1 |
| Kase, Y | 1 |
| Takeda, S | 1 |
| Ukai, K | 3 |
| Sakakura, Y | 3 |
| Majima, Y | 1 |
| Yasui, K | 2 |
| Asanuma, F | 2 |
| Hirano, Y | 1 |
| Shichijo, M | 1 |
| Deguchi, M | 1 |
| Arimura, A | 2 |
| Wang, D | 2 |
| Clement, P | 2 |
| Smitz, J | 2 |
| Derde, MP | 1 |
| Austin, CE | 1 |
| Foreman, JC | 1 |
| Plavec, D | 1 |
| Somogyi-Zalud, E | 1 |
| Godnic-Cvar, J | 1 |
| Clarke, RW | 1 |
| Cook, JA | 1 |
| Jones, AS | 1 |
| Rajakulasingam, K | 1 |
| Polosa, R | 1 |
| Lau, LC | 1 |
| Church, MK | 1 |
| Holgate, ST | 1 |
| Howarth, PH | 2 |
| Graf, P | 1 |
| Hallén, H | 1 |
| Slater, A | 1 |
| Smallman, LA | 1 |
| Logan, AC | 1 |
| Drake-Lee, AB | 1 |
| Furue, Y | 1 |
| Waterschoot, S | 1 |
| Simola, M | 1 |
| Malmberg, H | 1 |
| Kanthawatana, S | 1 |
| Maturim, W | 1 |
| Fooanant, S | 1 |
| Manorot, M | 1 |
| Trakultivakorn, M | 1 |
| Braat, JP | 1 |
| Mulder, PG | 1 |
| Fokkens, WJ | 1 |
| van Wijk, RG | 1 |
| Rijntjes, E | 1 |
| El-Naggar, MM | 1 |
| Takeuchi, K | 1 |
| Miyahara, Y | 1 |
| Yamagiwa, M | 1 |
| Ohkawa, C | 1 |
| Yamasaki, M | 2 |
| Mizutani, N | 3 |
| Sasaki, K | 2 |
| Matsumoto, T | 1 |
| Terada, T | 1 |
| Takenaka, H | 1 |
| Braunstein, G | 1 |
| Malaquin, F | 1 |
| Fajac, I | 1 |
| Melac, M | 1 |
| Frossard, N | 1 |
| Thomas, KE | 1 |
| Ollier, S | 1 |
| Ferguson, H | 1 |
| Davies, RJ | 1 |
| Gerth van Wijk, R | 1 |
| Dieges, PH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Reproducibility of Cell Counts in Nasal Lavage: A Comparison of Pooled Versus Non-Pooled Nasal Lavage Samples[NCT00229190] | 21 participants | Interventional | 2004-09-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for histamine and Nasal Obstruction
| Article | Year |
|---|---|
Mediators of nasal blockage in allergic rhinitis.
Topics: Histamine; Humans; Kinins; Leukotrienes; Nasal Obstruction; Platelet Activating Factor; Prostaglandi | 1997 |
5 trials available for histamine and Nasal Obstruction
| Article | Year |
|---|---|
Acoustic rhinometry compared with posterior rhinomanometry in the measurement of histamine- and bradykinin-induced changes in nasal airway patency.
Topics: Acoustics; Administration, Intranasal; Administration, Oral; Adult; Airway Resistance; Bradykinin; C | 1994 |
Comparative nasal effects of bradykinin and histamine: influence on nasal airways resistance and plasma protein exudation.
Topics: Administration, Inhalation; Adult; Airway Resistance; Blood Proteins; Bradykinin; Dose-Response Rela | 1993 |
Intranasal cold dry air is superior to histamine challenge in determining the presence and degree of nasal hyperreactivity in nonallergic noninfectious perennial rhinitis.
Topics: Adult; Cold Temperature; Cross-Over Studies; Female; Histamine; Humans; Male; Mucus; Nasal Cavity; N | 1998 |
Inhibition of histamine-induced nasal obstruction by cetirizine in allergic rhinitis.
Topics: Adult; Airway Resistance; Cetirizine; Female; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzi | 1992 |
The effect of intranasal azelastine, Rhinolast, on nasal airways obstruction and sneezing following provocation testing with histamine and allergen.
Topics: Administration, Intranasal; Adult; Allergens; Bronchodilator Agents; Female; Hemodynamics; Histamine | 1992 |
22 other studies available for histamine and Nasal Obstruction
| Article | Year |
|---|---|
Role of hematopoietic prostaglandin D synthase in biphasic nasal obstruction in guinea pig model of experimental allergic rhinitis.
Topics: Animals; Benzimidazoles; Dinoprostone; Disease Models, Animal; Eosinophils; Guinea Pigs; Histamine; | 2011 |
Canine model of nasal congestion and allergic rhinitis.
Topics: Aerosols; Airway Resistance; Ambrosia; Animals; Disease Models, Animal; Dogs; Female; Heart Rate; Hi | 2003 |
Effects of TAK-427 on acute nasal symptoms and nasal obstruction in guinea pig model of experimental allergic rhinitis.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Disease Models, Animal; Guinea Pigs; Histamine; Hi | 2003 |
Superoxide dismutase failed to attenuate allergen-induced nasal congestion in ragweed-sensitized dogs.
Topics: Administration, Inhalation; Allergens; Ambrosia; Animals; Dogs; Histamine; Injections, Intramuscular | 2005 |
Histamine receptors that influence blockage of the normal human nasal airway.
Topics: Adult; Cetirizine; Dose-Response Relationship, Drug; Drug Interactions; Histamine; Histamine Agonist | 2005 |
Histamine induces nasal obstruction via calcitonin gene-related peptide in sensitized guinea pigs.
Topics: Animals; Calcitonin Gene-Related Peptide; Guinea Pigs; Histamine; Male; Nasal Obstruction | 2007 |
Contribution of prostaglandin D2 via prostanoid DP receptor to nasal hyperresponsiveness in guinea pigs repeatedly exposed to antigen.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Administration, Intranasal; Alle | 2008 |
Concentrations of chemical mediators in nasal secretions after nasal allergen challenges in atopic patients.
Topics: Adolescent; Adult; Allergens; Blood Proteins; Case-Control Studies; Chymases; Eosinophil Granule Pro | 1995 |
Modified method of nonspecific nasal provocation with histamine for routine use.
Topics: Adolescent; Adult; Airway Resistance; Bronchial Hyperreactivity; Female; Histamine; Humans; Male; Mi | 1994 |
The effect of histamine challenge on nasal airflow sensation.
Topics: Administration, Intranasal; Airway Resistance; Female; Histamine; Humans; Male; Nasal Mucosa; Nasal | 1993 |
Clinical and rhinostereometric assessment of nasal mucosal swelling during histamine challenge.
Topics: Adolescent; Adult; Female; Histamine; Humans; Male; Nasal Decongestants; Nasal Mucosa; Nasal Obstruc | 1996 |
Mucociliary function in patients with nasal polyps.
Topics: Cilia; Culture Techniques; Dose-Response Relationship, Drug; Epithelium; Histamine; Humans; Mucocili | 1996 |
Involvement of thromboxane A2 in antigen-induced nasal blockage in guinea pigs.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Administration, Inhalation; Anim | 1997 |
An approach to the understanding of the nasal early-phase reaction induced by nasal allergen challenge.
Topics: Adult; Allergens; Chymases; Female; Histamine; Humans; Leukotriene C4; Male; Nasal Mucosa; Nasal Obs | 1997 |
Sensation of nasal airflow compared with nasal airway resistance in patients with rhinitis.
Topics: Airway Resistance; Bronchial Provocation Tests; Female; Histamine; Humans; Male; Manometry; Middle A | 1997 |
Evaluation of threshold criteria for the nasal histamine challenge test in perennial allergic rhinitis.
Topics: Adolescent; Adult; Child; Female; Histamine; Humans; Male; Middle Aged; Nasal Mucosa; Nasal Obstruct | 1997 |
Expression of interferon-gamma, interleukin-4 and interleukin-5 mRNA in the nasal mucosal membrane of rats with allergic rhinitis.
Topics: Airway Resistance; Animals; Azo Compounds; Blotting, Southern; Coloring Agents; Enzyme-Linked Immuno | 1998 |
Nasal passage patency in patients with allergic rhinitis measured by acoustic rhinometry: nasal responses after allergen and histamine provocation.
Topics: Adolescent; Adult; Allergens; Child; Female; Histamine; Humans; Male; Manometry; Middle Aged; Nasal | 1998 |
Involvement of thromboxane A2 and peptide leukotrienes in early and late phase nasal blockage in a guinea pig model of allergic rhinitis.
Topics: Animals; Anti-Allergic Agents; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Benzoquinones; Chrom | 2001 |
No involvement of interleukin-5 or eosinophils in experimental allergic rhinitis in guinea pigs.
Topics: Animals; Antibodies, Monoclonal; Bone Marrow Cells; Cell Degranulation; Cysteine; Eosinophils; Goble | 2002 |
Effect of oral antigen administration on nasal blockage in experimental allergic rhinitis in guinea pigs.
Topics: Administration, Oral; Airway Resistance; Animals; Antigens; Cedrus; Guinea Pigs; Histamine; Hypersen | 2002 |
Nasal hyper-responsiveness to histamine, methacholine and phentolamine in patients with perennial non-allergic rhinitis and in patients with infectious rhinitis.
Topics: Adolescent; Adult; Aged; Child; Chronic Disease; Drug Hypersensitivity; Histamine; Humans; Methachol | 1991 |