histamine has been researched along with Idiopathic Parkinson Disease in 34 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| " Diurnal fluctuation in histidine decarboxylase expression, the rate limiting enzyme for histamine production, and its disorder in neurodegenerative diseases." | 7.78 | Diurnal fluctuation in histidine decarboxylase expression, the rate limiting enzyme for histamine production, and its disorder in neurodegenerative diseases. ( Bao, AM; Hofman, MA; Shan, L; Swaab Dick, F; Van Someren, EJ; van Wamelen, DJ, 2012) |
| "We investigated histamine concentration in post-mortem brain samples of patients with Parkinson's disease (PD, n = 24), multiple system atrophy (MSA, n = 8) and age-matched controls (n = 27)." | 7.71 | Increased brain histamine levels in Parkinson's disease but not in multiple system atrophy. ( Anichtchik, OV; Eriksson, KS; Kalimo, H; Kaslin, J; Panula, P; Rinne, JO; Röyttä, M; Tuomisto, L, 2002) |
| "Several hypotheses have been raised about the dual role of histamine in neurological disorders, and evidences have shown its crucial involvement in the modulation of microglia-mediated neuroinflammation." | 4.95 | Dual role of histamine on microglia-induced neurodegeneration. ( Barata-Antunes, S; Bernardino, L; Cristóvão, AC; Pires, J; Rocha, SM, 2017) |
| " Diurnal fluctuation in histidine decarboxylase expression, the rate limiting enzyme for histamine production, and its disorder in neurodegenerative diseases." | 3.78 | Diurnal fluctuation in histidine decarboxylase expression, the rate limiting enzyme for histamine production, and its disorder in neurodegenerative diseases. ( Bao, AM; Hofman, MA; Shan, L; Swaab Dick, F; Van Someren, EJ; van Wamelen, DJ, 2012) |
| "We investigated histamine concentration in post-mortem brain samples of patients with Parkinson's disease (PD, n = 24), multiple system atrophy (MSA, n = 8) and age-matched controls (n = 27)." | 3.71 | Increased brain histamine levels in Parkinson's disease but not in multiple system atrophy. ( Anichtchik, OV; Eriksson, KS; Kalimo, H; Kaslin, J; Panula, P; Rinne, JO; Röyttä, M; Tuomisto, L, 2002) |
| "Blood histamine and serum histaminase activity were determined in a group of patients with Parkinson disease (PD) and in a group of healthy controls." | 3.68 | Decrease in blood histamine in drug-treated parkinsonian patients. ( Azevedo, MS; Coelho, MH; Manso, CF; Silva, IJ, 1991) |
| "Histamine was also found to damage the dopaminergic neurons in rat substantia nigra." | 1.38 | Histamine- and haloperidol-induced catalepsy in aged mice: differential responsiveness to L-DOPA. ( Ionov, ID; Severtsev, NN, 2012) |
| "Histamine content was significantly increased in the hypothalamus, hipocampus, and medulla oblongata." | 1.35 | Histaminergic activity in a rodent model of Parkinson's disease. ( Brus, H; Brus, R; Drab, J; Jochem, J; Körossy, E; Kostrzewa, RM; Noras, L; Nowak, P; Szkilnik, R, 2009) |
| "Histaminergic agents were given prior and daily for 1, 7 or 14 days after 6-OHDA infusion." | 1.34 | Involvement of brain endogenous histamine in the degeneration of dopaminergic neurons in 6-hydroxydopamine-lesioned rats. ( Chen, Z; Hu, DN; Liu, CQ; Liu, FX; Luo, JH, 2007) |
| "Histamine in human SN was stored in fibers and varicosities." | 1.31 | An altered histaminergic innervation of the substantia nigra in Parkinson's disease. ( Anichtchik, OV; Kalimo, H; Panula, P; Rinne, JO, 2000) |
| "Parkinson's disease is a major neurological disorder that primarily affects the nigral dopaminergic cells." | 1.31 | Modulation of histamine H3 receptors in the brain of 6-hydroxydopamine-lesioned rats. ( Anichtchik, OV; Haycock, JW; Huotari, M; Männistö, PT; Panula, P; Peitsaro, N, 2000) |
| "To estimate the effect of long-term administration of L-3,4-dihydroxyphenylalanine (L-Dopa) on methylation of compounds not formed from it, the urinary excretion of histamine and its methylated metabolites was studied in rats and guinea pigs fed L-Dopa in their diets and in patients with Parkinson's disease being treated with L-Dopa." | 1.25 | Effect of L-DOPA on endogenous histamine metabolism. ( Muenter, MD; Sharpless, NS; Tyce, GM, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (23.53) | 18.7374 |
| 1990's | 5 (14.71) | 18.2507 |
| 2000's | 8 (23.53) | 29.6817 |
| 2010's | 10 (29.41) | 24.3611 |
| 2020's | 3 (8.82) | 2.80 |
| Authors | Studies |
|---|---|
| Sharma, A | 2 |
| Muresanu, DF | 2 |
| Patnaik, R | 1 |
| Menon, PK | 1 |
| Tian, ZR | 2 |
| Sahib, S | 1 |
| Castellani, RJ | 1 |
| Nozari, A | 2 |
| Lafuente, JV | 2 |
| Buzoianu, AD | 2 |
| Skaper, SD | 1 |
| Bryukhovetskiy, I | 1 |
| Manzhulo, I | 1 |
| Wiklund, L | 2 |
| Sharma, HS | 2 |
| Feng, L | 1 |
| Huang, H | 1 |
| Chen, L | 1 |
| Chen, YC | 2 |
| Baronio, D | 1 |
| Semenova, S | 2 |
| Abdurakhmanova, S | 1 |
| Panula, P | 5 |
| Zhou, P | 1 |
| Homberg, JR | 1 |
| Fang, Q | 1 |
| Wang, J | 1 |
| Li, W | 1 |
| Meng, X | 1 |
| Shen, J | 1 |
| Luan, Y | 1 |
| Liao, P | 1 |
| Swaab, DF | 3 |
| Shan, L | 5 |
| Liu, C | 2 |
| Bañuelos-Cabrera, I | 1 |
| Valle-Dorado, MG | 1 |
| Aldana, BI | 1 |
| Orozco-Suárez, SA | 1 |
| Rocha, L | 1 |
| Yang, X | 1 |
| Zhang, J | 1 |
| Han, H | 1 |
| Wang, X | 1 |
| Liu, Z | 1 |
| Xu, Y | 1 |
| Dauvilliers, Y | 1 |
| Siegel, JM | 1 |
| Rozov, S | 1 |
| Sundvik, M | 1 |
| Bonkowsky, JL | 1 |
| Barata-Antunes, S | 1 |
| Cristóvão, AC | 1 |
| Pires, J | 1 |
| Rocha, SM | 1 |
| Bernardino, L | 1 |
| Ionov, ID | 2 |
| Nowak, P | 1 |
| Noras, L | 1 |
| Jochem, J | 1 |
| Szkilnik, R | 1 |
| Brus, H | 1 |
| Körossy, E | 1 |
| Drab, J | 1 |
| Kostrzewa, RM | 1 |
| Brus, R | 1 |
| Liu, CQ | 2 |
| Balesar, R | 2 |
| Hofman, MA | 2 |
| Bao, AM | 3 |
| Bossers, K | 1 |
| Luchetti, S | 1 |
| Lethbridge, N | 1 |
| Chazot, PL | 1 |
| Severtsev, NN | 1 |
| van Wamelen, DJ | 1 |
| Van Someren, EJ | 1 |
| Swaab Dick, F | 1 |
| Chen, Z | 2 |
| Hu, WW | 1 |
| DENKER, P | 1 |
| EFFRON, AS | 1 |
| WINTHER, K | 1 |
| Liu, FX | 1 |
| Hu, DN | 1 |
| Luo, JH | 1 |
| Agúndez, JA | 1 |
| Luengo, A | 1 |
| Herráez, O | 1 |
| Martínez, C | 1 |
| Alonso-Navarro, H | 1 |
| Jiménez-Jiménez, FJ | 1 |
| García-Martín, E | 1 |
| Garbarg, M | 1 |
| Javoy-Agid, F | 1 |
| Schwartz, JC | 1 |
| Agid, Y | 1 |
| Baron, R | 1 |
| Feldmann, R | 1 |
| Lindner, V | 1 |
| Nakamura, S | 1 |
| Ohnishi, K | 1 |
| Nishimura, M | 1 |
| Suenaga, T | 1 |
| Akiguchi, I | 1 |
| Kimura, J | 1 |
| Kimura, T | 1 |
| Goodchild, RE | 1 |
| Court, JA | 1 |
| Hobson, I | 1 |
| Piggott, MA | 1 |
| Perry, RH | 1 |
| Ince, P | 1 |
| Jaros, E | 1 |
| Perry, EK | 1 |
| Anichtchik, OV | 3 |
| Rinne, JO | 2 |
| Kalimo, H | 2 |
| Huotari, M | 1 |
| Peitsaro, N | 1 |
| Haycock, JW | 1 |
| Männistö, PT | 1 |
| Eriksson, KS | 1 |
| Kaslin, J | 1 |
| Tuomisto, L | 1 |
| Röyttä, M | 1 |
| de Silva, L | 1 |
| Sharpless, NS | 1 |
| Muenter, MD | 1 |
| Tyce, GM | 1 |
| Prell, GD | 1 |
| Green, JP | 1 |
| Coelho, MH | 1 |
| Silva, IJ | 1 |
| Azevedo, MS | 1 |
| Manso, CF | 1 |
| Jones, DG | 2 |
| Turnbull, MJ | 2 |
| Lenman, JA | 2 |
| Robertson, MA | 2 |
| Zanini, AC | 1 |
8 reviews available for histamine and Idiopathic Parkinson Disease
| Article | Year |
|---|---|
Histamine H3 and H4 receptors modulate Parkinson's disease induced brain pathology. Neuroprotective effects of nanowired BF-2649 and clobenpropit with anti-histamine-antibody therapy.
Topics: Corpus Striatum; Histamine; Humans; Imidazoles; Neuroprotective Agents; Parkinson Disease; Receptors | 2021 |
Nanodelivery of Histamine H3/H4 Receptor Modulators BF-2649 and Clobenpropit with Antibodies to Amyloid Beta Peptide in Combination with Alpha Synuclein Reduces Brain Pathology in Parkinson's Disease.
Topics: alpha-Synuclein; Amyloid beta-Peptides; Antibodies, Monoclonal; Brain; Drug Inverse Agonism; Histami | 2023 |
Role of histaminergic system in blood-brain barrier dysfunction associated with neurological disorders.
Topics: Alzheimer Disease; Blood-Brain Barrier; Epilepsy; Histamine; Humans; Inflammation; Mast Cells; Parki | 2014 |
Interactions of the histamine and hypocretin systems in CNS disorders.
Topics: Alzheimer Disease; Animals; Histamine; Histamine Agonists; Histamine H1 Antagonists; Histamine H3 An | 2015 |
Dual role of histamine on microglia-induced neurodegeneration.
Topics: Animals; Dopaminergic Neurons; Histamine; Humans; Inflammation; Lipopolysaccharides; Microglia; Neur | 2017 |
Self-amplification of nigral degeneration in Parkinson's disease: a hypothesis.
Topics: Animals; Blood-Brain Barrier; Brain Ischemia; Cerebrovascular Circulation; Glutamic Acid; Histamine; | 2008 |
[Histamine and diseases of central nervous system].
Topics: Alzheimer Disease; Brain Ischemia; Epilepsy; Histamine; Humans; Parkinson Disease | 2004 |
[Pharmacology of the Parkinsonism syndrome].
Topics: Acetylcholine; Catecholamines; Histamine; Humans; Melanins; Nervous System; Parkinson Disease; Serot | 1967 |
26 other studies available for histamine and Idiopathic Parkinson Disease
| Article | Year |
|---|---|
Cerebral Dopamine Neurotrophic Factor Regulates Multiple Neuronal Subtypes and Behavior.
Topics: Animals; Behavior, Animal; Brain; Dopaminergic Neurons; GABAergic Neurons; Gene Deletion; Histamine; | 2020 |
Histamine-4 receptor antagonist JNJ7777120 inhibits pro-inflammatory microglia and prevents the progression of Parkinson-like pathology and behaviour in a rat model.
Topics: alpha-Synuclein; Animals; Behavior, Animal; Brain; Corpus Striatum; Disease Models, Animal; Disease | 2019 |
Association of histamine N-methyltransferase Thr105Ile polymorphism with Parkinson's disease and schizophrenia in Han Chinese: a case-control study.
Topics: Adult; Alleles; Asian People; Case-Control Studies; China; Female; Gene Frequency; Genetic Predispos | 2015 |
A Novel Developmental Role for Dopaminergic Signaling to Specify Hypothalamic Neurotransmitter Identity.
Topics: Animals; Dopaminergic Neurons; Histamine; Hypothalamus; Levodopa; Neurotransmitter Agents; Orexins; | 2016 |
Histaminergic activity in a rodent model of Parkinson's disease.
Topics: Adrenergic Agents; Animals; Animals, Newborn; Apomorphine; Brain; Disease Models, Animal; Dopamine; | 2009 |
Neuronal histamine production remains unaltered in Parkinson's disease despite the accumulation of Lewy bodies and Lewy neurites in the tuberomamillary nucleus.
Topics: Biomarkers; Histamine; Humans; Hypothalamic Area, Lateral; Lewy Bodies; Neurites; Neurons; Parkinson | 2012 |
Alterations in the histaminergic system in the substantia nigra and striatum of Parkinson's patients: a postmortem study.
Topics: Aged; Aged, 80 and over; Corpus Striatum; Female; Histamine; Histamine N-Methyltransferase; Humans; | 2012 |
Histamine- and haloperidol-induced catalepsy in aged mice: differential responsiveness to L-DOPA.
Topics: Aging; Animals; Antiparkinson Agents; Catalepsy; Disease Models, Animal; Dopamine; Dose-Response Rel | 2012 |
Diurnal fluctuation in histidine decarboxylase expression, the rate limiting enzyme for histamine production, and its disorder in neurodegenerative diseases.
Topics: Alzheimer Disease; Case-Control Studies; Circadian Rhythm; Gene Expression; Histamine; Histidine; Hu | 2012 |
A comparative study of antihistaminic and other drugs in Parkinson's disease.
Topics: Histamine; Humans; Parkinson Disease; Parkinsonian Disorders | 1950 |
[Treatment of paralysis agitans with some new preparations: parpanit, diparcol, and phenergan].
Topics: Cyclopentanes; Histamine; Parkinson Disease; Parkinsonian Disorders; Phenothiazines; Promethazine | 1950 |
Involvement of brain endogenous histamine in the degeneration of dopaminergic neurons in 6-hydroxydopamine-lesioned rats.
Topics: Analysis of Variance; Animals; Behavior, Animal; Brain; Cell Count; Disease Models, Animal; Dopamine | 2007 |
Nonsynonymous polymorphisms of histamine-metabolising enzymes in patients with Parkinson's disease.
Topics: Adult; Aged; Aged, 80 and over; Amine Oxidase (Copper-Containing); Female; Genetic Predisposition to | 2008 |
Brain histidine decarboxylase activity in Parkinson's disease.
Topics: Brain; Carboxy-Lyases; Histamine; Histidine Decarboxylase; Humans; Neurotransmitter Agents; Parkinso | 1983 |
Small fibre function in primary autonomic failure.
Topics: Afferent Pathways; Autonomic Nervous System; Axons; Female; Histamine; Humans; Hypotension, Orthosta | 1993 |
Large neurons in the tuberomammillary nucleus in patients with Parkinson's disease and multiple system atrophy.
Topics: Aged; Aged, 80 and over; Amyotrophic Lateral Sclerosis; Brain Chemistry; Cell Size; Female; Histamin | 1996 |
Distribution of histamine H3-receptor binding in the normal human basal ganglia: comparison with Huntington's and Parkinson's disease cases.
Topics: Aged; Aged, 80 and over; Autoradiography; Female; Globus Pallidus; Histamine; Humans; Huntington Dis | 1999 |
An altered histaminergic innervation of the substantia nigra in Parkinson's disease.
Topics: Adult; Aged; Aged, 80 and over; Cell Count; Dopamine; Female; Histamine; Histidine Decarboxylase; Hu | 2000 |
Modulation of histamine H3 receptors in the brain of 6-hydroxydopamine-lesioned rats.
Topics: Amygdala; Animals; Brain; Corpus Striatum; Disease Models, Animal; Functional Laterality; Gene Expre | 2000 |
Increased brain histamine levels in Parkinson's disease but not in multiple system atrophy.
Topics: Aged; Brain; Brain Chemistry; Female; Globus Pallidus; Histamine; Humans; Immunohistochemistry; Male | 2002 |
Biochemical mechanisms and management of choreiform movement disorders.
Topics: Acetylcholine; Basal Ganglia; Chorea; Corpus Striatum; Dopamine; Dyskinesia, Drug-Induced; Extrapyra | 1977 |
Effect of L-DOPA on endogenous histamine metabolism.
Topics: Acetates; Adult; Aged; Animals; Carbidopa; Depression, Chemical; Female; Guinea Pigs; Histamine; Hum | 1975 |
Histamine metabolites and pros-methylimidazoleacetic acid in human cerebrospinal fluid.
Topics: Adult; Aged; Aging; Female; Histamine; Humans; Huntington Disease; Imidazoles; Male; Middle Aged; Pa | 1991 |
Decrease in blood histamine in drug-treated parkinsonian patients.
Topics: Adult; Aged; Amine Oxidase (Copper-Containing); Antiparkinson Agents; Carbidopa; Female; Histamine; | 1991 |
Effect of amantadine on the urinary excretion of some monoamines and metabolites in normal and Parkinsonian subjects.
Topics: Adult; Aged; Amantadine; Catecholamines; Dihydroxyphenylalanine; Dopamine; Epinephrine; Female; Hist | 1972 |
Proceedings: Effect of amantadine on the urinary excretion of some monoamines and metabolites in normal and parkinsonian subjects.
Topics: Amantadine; Amines; Dihydroxyphenylalanine; Dopamine; Epinephrine; Histamine; Homovanillic Acid; Hum | 1972 |