histamine has been researched along with Drug Withdrawal Symptoms in 25 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "We investigated whether the deterioration in asthma control reported following cessation of theophylline was due to tolerance to theophylline." | 9.08 | The airway effects of stopping regular oral theophylline in patients with asthma. ( Bennett, JA; Pavord, ID; Tattersfield, AE; Thompson Coon, J; Wilding, PJ, 1998) |
| "We investigated whether the deterioration in asthma control reported following cessation of theophylline was due to tolerance to theophylline." | 5.08 | The airway effects of stopping regular oral theophylline in patients with asthma. ( Bennett, JA; Pavord, ID; Tattersfield, AE; Thompson Coon, J; Wilding, PJ, 1998) |
| "In the present study, the influence of withdrawal from repeated administration of morphine on intra-ventral hippocampal microinjection of histamine-induced anxiety-like behavior was investigated in male Wistar rats." | 3.76 | Withdrawal from repeated administration of morphine alters histamine-induced anxiogenic effects produced by intra-ventral hippocampal microinjection. ( Khodarahmi, P; Oryan, S; Rezayof, A; Zarrindast, MR, 2010) |
| " Mitragynine (3-10 microM) did not show any effect on the smooth muscle contraction induced by acetylcholine or histamine." | 3.69 | Inhibitory effect of mitragynine, an alkaloid with analgesic effect from Thai medicinal plant Mitragyna speciosa, on electrically stimulated contraction of isolated guinea-pig ileum through the opioid receptor. ( Horie, S; Watanabe, K; Yamamoto, LT; Yano, S, 1997) |
| "Histamine plays an important role in morphine addiction and memory-dependent behavior." | 1.36 | Ameliorating effect of histamine on impairment of cued fear extinction induced by morphine withdrawal in histidine decarboxylase gene knockout mice. ( Chen, Z; Feng, B; Gong, YX; Ohtsu, H; Shou, WT; Wang, HJ; Zhang, WP, 2010) |
| "Cimetidine was without effect on wet-dog shakes, burrowing, and body weight loss." | 1.29 | The role of histaminergic-noradrenergic axis in naloxone-induced withdrawal symptoms in mice. ( el Kadi, AO; Sharif, SI, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (60.00) | 18.7374 |
| 1990's | 4 (16.00) | 18.2507 |
| 2000's | 2 (8.00) | 29.6817 |
| 2010's | 4 (16.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abe, K | 1 |
| Kobayashi, K | 1 |
| Yoshino, S | 1 |
| Taguchi, K | 1 |
| Nojima, H | 1 |
| Gong, YX | 2 |
| Zhang, WP | 2 |
| Shou, WT | 2 |
| Zhong, K | 1 |
| Chen, Z | 2 |
| Zarrindast, MR | 1 |
| Khodarahmi, P | 1 |
| Rezayof, A | 1 |
| Oryan, S | 1 |
| Feng, B | 1 |
| Wang, HJ | 1 |
| Ohtsu, H | 1 |
| CHERRY, A | 1 |
| Rae, GA | 1 |
| De Moraes, S | 1 |
| Agnoli, A | 1 |
| Denaro, A | 1 |
| Ceci, E | 1 |
| Falaschi, P | 1 |
| el Kadi, AO | 1 |
| Sharif, SI | 1 |
| Watanabe, K | 1 |
| Yano, S | 1 |
| Horie, S | 1 |
| Yamamoto, LT | 1 |
| Noto, T | 1 |
| Nagasaki, M | 1 |
| Yomota, E | 1 |
| Endo, T | 1 |
| Bennett, JA | 1 |
| Thompson Coon, J | 1 |
| Pavord, ID | 1 |
| Wilding, PJ | 1 |
| Tattersfield, AE | 1 |
| Leuppi, JD | 1 |
| Salome, CM | 1 |
| Jenkins, CR | 1 |
| Anderson, SD | 1 |
| Xuan, W | 1 |
| Marks, GB | 1 |
| Koskela, H | 1 |
| Brannan, JD | 1 |
| Freed, R | 1 |
| Andersson, M | 1 |
| Chan, HK | 1 |
| Woolcock, AJ | 1 |
| Nath, C | 1 |
| Gupta, MB | 1 |
| French, SW | 1 |
| Palmer, DS | 1 |
| Narod, ME | 1 |
| Wong, CL | 1 |
| Roberts, MB | 1 |
| Glick, SD | 1 |
| Crane, LA | 1 |
| Mazurkiewicz-Kwilecki, IM | 1 |
| Bielkiewicz, B | 1 |
| Mazurkiewicz-Kwilecki, I | 1 |
| Henwood, RW | 2 |
| Mazurikiewicz-Kwilecki, IM | 1 |
| Verberne, AJ | 1 |
| Fennessy, MR | 1 |
| Lewis, SJ | 1 |
| Taylor, DA | 1 |
| Oishi, R | 1 |
| Nishibori, M | 1 |
| Itoh, Y | 1 |
| Saeki, K | 1 |
| Fukuda, T | 1 |
| Araki, Y | 1 |
| Fennerty, AG | 1 |
| Banks, J | 1 |
| Ebden, P | 1 |
| Bevan, C | 1 |
| Sultan, IH | 1 |
| Collier, HO | 1 |
| Lorenzetti, OJ | 1 |
| Sancilio, LF | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Prospective One Year Study of the Causes, Characteristics, Mechanisms and Kinetics of Exacerbations in Subjects With Asthma[NCT00512954] | 100 participants (Anticipated) | Observational | 2007-04-30 | Completed | |||
| Evaluation of the Usefulness of Induced Sputum Eosinophilia, eNO and Bronchial Hyperresponsiveness in Predicting the Failure of Inhaled Corticosteroids Dose Reduction in Children and Adolescents With Stable Asthma[NCT03788057] | 50 participants (Anticipated) | Interventional | 2016-02-01 | Recruiting | |||
| Examination of Palonosetron and Hydroxyzine Pre-treatment as a Possible Method to Reduce the Objective Signs of Experimentally-induced Acute Opioid Withdrawal in Humans: a Double-blind, Randomized, Placebo-controlled Crossover Study[NCT00661674] | 10 participants (Actual) | Interventional | 2008-04-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"The OOWS is a 13-item instrument documenting physically observable signs of withdrawal, which are rated as present (1) or absent (0) during the observation period. Maximum score possible = 13, minimum score possible = 0. T=15 minutes post naloxone administration coordinates with T = 180 (min) for the entire study session.~OOWS scores at T=180 is the primary outcome measure of the study compared with baseline OOWS scores at T=-30 (30 minutes prior to study medication administration). Reported time frames are in relation to time past since administration of study medications.~Mean post-Naloxone OOWS scores (+/- SEM) were determined for pretreatment groups" (NCT00661674)
Timeframe: Change from baseline in OOWS score at 180 minutes (15 minutes post naloxone administration)
| Intervention | units on a scale (OOWS Scale) (Mean) |
|---|---|
| Placebo | 3.5 |
| Palonosetron | 1.0 |
| Palonosetron + Hydroxyzine | 0 |
"The SOWS score is composed of 16 subjective symptoms rated on a scale of 0 to 4 (0=not at all, 4=extremely) based on what subjects were experiencing at the time of testing. 15 minutes post naloxone administration coordinates with T = 180 (min) for the entire study session.~The highest score possible (64) would indicate that the individual was experiencing every symptom of opioid withdrawal to the fullest extent possible while the lowest score (0) would indicate that the individual was not experiencing any symptoms of opioid withdrawal.~Mean post-naloxone SOWS scores (+/- SEM) were computed for pretreatment groups: Placebo, palonosetron, and palonosetron with hydroxyzine" (NCT00661674)
Timeframe: Change from baseline in SOWS score at 180 minutes (15 minutes post naloxone administration)
| Intervention | units on a scale (SOWS Scale) (Mean) |
|---|---|
| Placebo | 6.0 |
| Palonosetron | 4.0 |
| Palonosetron + Hydroxyzine | 3.5 |
1 trial available for histamine and Drug Withdrawal Symptoms
| Article | Year |
|---|---|
The airway effects of stopping regular oral theophylline in patients with asthma.
Topics: Administration, Oral; Adult; Asthma; Bronchoconstriction; Bronchodilator Agents; Cyclic AMP; Double- | 1998 |
24 other studies available for histamine and Drug Withdrawal Symptoms
| Article | Year |
|---|---|
Withdrawal of repeated morphine enhances histamine-induced scratching responses in mice.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Corticosterone; Dose-Response Relationship, Drug; His | 2015 |
Morphine induces conditioned place preference behavior in histidine decarboxylase knockout mice.
Topics: Analgesics, Opioid; Animals; Brain; Conditioning, Classical; Extinction, Psychological; Histamine; H | 2010 |
Withdrawal from repeated administration of morphine alters histamine-induced anxiogenic effects produced by intra-ventral hippocampal microinjection.
Topics: Analysis of Variance; Animals; Anxiety; Behavior, Animal; Hippocampus; Histamine; Histamine Antagoni | 2010 |
Ameliorating effect of histamine on impairment of cued fear extinction induced by morphine withdrawal in histidine decarboxylase gene knockout mice.
Topics: Animals; Brain; Cues; Extinction, Psychological; Extracellular Signal-Regulated MAP Kinases; Fear; H | 2010 |
Anti-histamine withdrawal symptoms; report of three cases.
Topics: Histamine; Humans; Substance Withdrawal Syndrome | 1949 |
Presynaptic alpha 2-adrenoceptor subsensitivity in the morphine-withdrawn mouse vas deferens.
Topics: Animals; Clonidine; Dose-Response Relationship, Drug; Electric Stimulation; Histamine; Humans; In Vi | 1984 |
On the etiopathogenesis of migraine: a possible link between the amines and endorphin hypotheses.
Topics: Adult; Clonidine; Dopamine; Endorphins; Enkephalin, Methionine; Enkephalins; Female; Histamine; Huma | 1982 |
The role of histaminergic-noradrenergic axis in naloxone-induced withdrawal symptoms in mice.
Topics: Animals; Behavior, Animal; Chlorpheniramine; Cimetidine; Dose-Response Relationship, Drug; Histamine | 1996 |
Inhibitory effect of mitragynine, an alkaloid with analgesic effect from Thai medicinal plant Mitragyna speciosa, on electrically stimulated contraction of isolated guinea-pig ileum through the opioid receptor.
Topics: Acetylcholine; Analgesics; Animals; Clonidine; Diterpene Alkaloids; Electric Stimulation; Guinea Pig | 1997 |
Gastric mucosal function following withdrawal of omeprazole in rats.
Topics: Analgesics, Non-Narcotic; Animals; Anti-Ulcer Agents; Aspirin; Gastric Acid; Gastric Mucosa; Gastrin | 1998 |
Predictive markers of asthma exacerbation during stepwise dose reduction of inhaled corticosteroids.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Asthma; Breath Tests; Bronchial Hyperreactivity; B | 2001 |
Predictive markers of asthma exacerbation during stepwise dose reduction of inhaled corticosteroids.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Asthma; Breath Tests; Bronchial Hyperreactivity; B | 2001 |
Predictive markers of asthma exacerbation during stepwise dose reduction of inhaled corticosteroids.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Asthma; Breath Tests; Bronchial Hyperreactivity; B | 2001 |
Predictive markers of asthma exacerbation during stepwise dose reduction of inhaled corticosteroids.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Asthma; Breath Tests; Bronchial Hyperreactivity; B | 2001 |
Role of central histaminergic system in lorazepam withdrawal syndrome in rats.
Topics: Acoustic Stimulation; Animals; Anti-Anxiety Agents; Epilepsy, Reflex; Histamine; Histamine Agonists; | 2001 |
Effect of withdrawal from chronic ethanol ingestion on the cAMP response of cerebral cortical slices using the agonists histamine, serotonin, and other neurotransmitters.
Topics: Acetylcholine; Aminobutyrates; Animals; Cerebral Cortex; Cyclic AMP; Diet; Dopamine; Ethanol; gamma- | 1975 |
The effects of D-histiding on the expression of morphine tolerance and physical dependence in mice.
Topics: Animals; Brain; Drug Tolerance; Histamine; Histidine; Humans; Male; Mice; Mice, Inbred Strains; Morp | 1977 |
Opiate-like and abstinence-like effects of intracerebral histamine administration in rats.
Topics: Analgesia; Animals; Behavior, Animal; Brain; Catalepsy; Cerebral Aqueduct; Female; Hippocampus; Hist | 1978 |
The effects of chronic morphine treatment on histamine concentration and histidine decarboxylase activity in rat brain.
Topics: Animals; Brain; Brain Chemistry; Carboxy-Lyases; Histamine; Histidine Decarboxylase; Humans; Male; M | 1978 |
Alterations in brain endogenous histamine levels in rats after chronic morphine treatment and morphine withdrawal.
Topics: Animals; Body Weight; Brain; Brain Stem; Cerebral Cortex; Histamine; Humans; Male; Methadone; Morphi | 1976 |
Possible role of brain histamine in morphine addiction.
Topics: Animals; Brain; Brain Stem; Cerebral Cortex; Histamine; Humans; Hypothalamus; Male; Methadone; Morph | 1975 |
Involvement of brain histamine in delta 9-tetrahydrocannabinol tolerance and withdrawal.
Topics: Animals; Behavior, Animal; Body Temperature; Brain; Dronabinol; Drug Tolerance; Histamine; Male; Pov | 1985 |
Histamine turnover in the brain of morphine-dependent mice.
Topics: Animals; Brain; Folic Acid Antagonists; Histamine; Histidine; Male; Methylhistamines; Mice; Mice, In | 1988 |
The effect of cigarette withdrawal on asthmatics who smoke.
Topics: Adult; Airway Resistance; Asthma; Bronchi; Female; Histamine; Humans; Male; Middle Aged; Smoking; Su | 1987 |
Cortisone withdrawal rebound phenomena and histamine.
Topics: Asthma; Histamine; Histamine Release; Humans; Ileum; Muscle Contraction; Prednisone; Substance Withd | 1971 |
Supersensitivity and dependence.
Topics: Acetylcholine; Animals; Drug Tolerance; Histamine; Humans; Models, Biological; Models, Psychological | 1968 |
Morphine dependent rats as a model for evaluating potential addiction liability of analgesic compounds.
Topics: Analgesics; Animals; Apomorphine; Azepines; Behavior, Animal; Codeine; Dextropropoxyphene; Diphenhyd | 1970 |