histamine has been researched along with Disorders of Excessive Somnolence in 9 studies
Disorders of Excessive Somnolence: Disorders characterized by hypersomnolence during normal waking hours that may impair cognitive functioning. Subtypes include primary hypersomnia disorders (e.g., IDIOPATHIC HYPERSOMNOLENCE; NARCOLEPSY; and KLEINE-LEVIN SYNDROME) and secondary hypersomnia disorders where excessive somnolence can be attributed to a known cause (e.g., drug affect, MENTAL DISORDERS, and SLEEP APNEA SYNDROME). (From J Neurol Sci 1998 Jan 8;153(2):192-202; Thorpy, Principles and Practice of Sleep Medicine, 2nd ed, p320)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To examine whether cerebrospinal fluid (CSF) histamine contents are altered in human narcolepsy and whether these alterations are specific to hypocretin deficiency, as defined by low CSF hypocretin-1." | 7.75 | Decreased CSF histamine in narcolepsy with and without low CSF hypocretin-1 in comparison to healthy controls. ( Mignot, E; Nevsimalova, S; Nishino, S; Sakurai, E; Watanabe, T; Yanai, K; Yoshida, Y, 2009) |
| "To (1) replicate our prior result of low cerebrospinal fluid (CSF) histamine levels in human narcolepsy in a different sample population and to (2) evaluate if histamine contents are altered in other types of hypersomnia with and without hypocretin deficiency." | 7.75 | CSF histamine contents in narcolepsy, idiopathic hypersomnia and obstructive sleep apnea syndrome. ( Chiba, S; Inoue, Y; Kanbayashi, T; Kodama, T; Kondo, H; Nishino, S; Satoh, S; Shimizu, T, 2009) |
| "CSF histamine and tele-methylhistamine did not significantly differ between patients with narcolepsy-cataplexy and other etiologies of non-hypocretin-1 deficient central hypersomnias; these measurements, therefore, are not useful in assessing the etiology or severity of centrally mediated hypersomnia." | 3.78 | Normal cerebrospinal fluid histamine and tele-methylhistamine levels in hypersomnia conditions. ( Bayard, S; Croyal, M; Dauvilliers, Y; Delallée, N; Jaussent, I; Robert, P; Scholz, S; Schwartz, JC, 2012) |
| "To examine whether cerebrospinal fluid (CSF) histamine contents are altered in human narcolepsy and whether these alterations are specific to hypocretin deficiency, as defined by low CSF hypocretin-1." | 3.75 | Decreased CSF histamine in narcolepsy with and without low CSF hypocretin-1 in comparison to healthy controls. ( Mignot, E; Nevsimalova, S; Nishino, S; Sakurai, E; Watanabe, T; Yanai, K; Yoshida, Y, 2009) |
| "To (1) replicate our prior result of low cerebrospinal fluid (CSF) histamine levels in human narcolepsy in a different sample population and to (2) evaluate if histamine contents are altered in other types of hypersomnia with and without hypocretin deficiency." | 3.75 | CSF histamine contents in narcolepsy, idiopathic hypersomnia and obstructive sleep apnea syndrome. ( Chiba, S; Inoue, Y; Kanbayashi, T; Kodama, T; Kondo, H; Nishino, S; Satoh, S; Shimizu, T, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (44.44) | 29.6817 |
| 2010's | 5 (55.56) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Scammell, TE | 1 |
| Mochizuki, T | 1 |
| Nishino, S | 3 |
| Sakurai, E | 1 |
| Nevsimalova, S | 1 |
| Yoshida, Y | 1 |
| Watanabe, T | 1 |
| Yanai, K | 1 |
| Mignot, E | 1 |
| Kanbayashi, T | 1 |
| Kodama, T | 2 |
| Kondo, H | 1 |
| Satoh, S | 1 |
| Inoue, Y | 1 |
| Chiba, S | 1 |
| Shimizu, T | 1 |
| Burgess, CR | 1 |
| Bassetti, CL | 1 |
| Baumann, CR | 1 |
| Dauvilliers, Y | 2 |
| Croyal, M | 2 |
| Robert, P | 2 |
| Schwartz, JC | 2 |
| Hartmann, A | 1 |
| Worbe, Y | 1 |
| Arnulf, I | 1 |
| Rye, DB | 1 |
| Delallée, N | 1 |
| Jaussent, I | 1 |
| Scholz, S | 1 |
| Bayard, S | 1 |
| Soya, A | 1 |
| Song, YH | 1 |
| Honda, Y | 1 |
| Fujiki, N | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Multi-Signal Based Monitoring System for CNS Hypersomnias : A 10-year Longitudinal Study[NCT05443373] | 600 participants (Anticipated) | Observational | 2020-06-04 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for histamine and Disorders of Excessive Somnolence
| Article | Year |
|---|---|
Histamine and orexin in the control of arousal, locomotion, and motivation.
Topics: Animals; Arousal; Disorders of Excessive Somnolence; Histamine; Histidine Decarboxylase; Humans; Hyp | 2010 |
8 other studies available for histamine and Disorders of Excessive Somnolence
| Article | Year |
|---|---|
Is low histamine a fundamental cause of sleepiness in narcolepsy and idiopathic hypersomnia?
Topics: Brain; Cataplexy; Disorders of Excessive Somnolence; Histamine; Humans; Intracellular Signaling Pept | 2009 |
Decreased CSF histamine in narcolepsy with and without low CSF hypocretin-1 in comparison to healthy controls.
Topics: Adult; Cataplexy; Disorders of Excessive Somnolence; Female; Histamine; Humans; Intracellular Signal | 2009 |
CSF histamine contents in narcolepsy, idiopathic hypersomnia and obstructive sleep apnea syndrome.
Topics: Adult; Aged; Aged, 80 and over; Antidepressive Agents; Cataplexy; Central Nervous System Stimulants; | 2009 |
Cerebrospinal fluid histamine levels are decreased in patients with narcolepsy and excessive daytime sleepiness of other origin.
Topics: Adult; Aged; Disorders of Excessive Somnolence; Female; Histamine; Humans; Idiopathic Hypersomnia; M | 2010 |
Increasing histamine neurotransmission in Gilles de la Tourette syndrome.
Topics: Adolescent; Disorders of Excessive Somnolence; Histamine; Humans; Male; Piperidines; Receptors, Hist | 2012 |
Inability to replicate cerebrospinal fluid histamine deficits in the primary hypersomnias: a back to the drawing board moment.
Topics: Disorders of Excessive Somnolence; Female; Histamine; Humans; Male; Methylhistamines | 2012 |
Normal cerebrospinal fluid histamine and tele-methylhistamine levels in hypersomnia conditions.
Topics: Adult; Disorders of Excessive Somnolence; Female; Histamine; Humans; Male; Methylhistamines; Middle | 2012 |
CSF histamine levels in rats reflect the central histamine neurotransmission.
Topics: Amphetamine; Animals; Benzhydryl Compounds; Brain; Central Nervous System Stimulants; Circadian Rhyt | 2008 |