histamine has been researched along with Disease Models, Animal in 763 studies
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Histamine is an immune modulator, neuroprotective, and remyelinating agent, beneficially acting on skeletal muscles and promoting anti-inflammatory features in amyotrophic lateral sclerosis (ALS) microglia." | 9.01 | Histaminergic transmission slows progression of amyotrophic lateral sclerosis. ( Amadio, S; Apolloni, S; Cavallaro, S; Fabbrizio, P; Ferri, A; Latagliata, EC; Madaro, L; Morello, G; Proietti, D; Puglisi-Allegra, S; Salvatori, I; Spampinato, AG; Volonté, C, 2019) |
| "The histamine H4 receptor is expressed preferentially on immune cells, indicating a possible role of the H4 receptor in inflammation." | 8.86 | Does the histamine H4 receptor have a pro- or anti-inflammatory role in murine bronchial asthma? ( Beermann, S; Neumann, D; Seifert, R, 2010) |
| "OVA treatment successfully induced AR model in mice with significantly increased sneezing and rubbing frequency, elevated levels of serum histamine, IL-1β, IL-10 and OVA-specific IgE." | 8.31 | Bufotalin ameliorates ovalbumin-induced allergic rhinitis by restoring the Tregs. ( Ji, Q; Li, L; Ren, S, 2023) |
| " The current study evaluated the pharmacological activity of gabapentin (GBP) and its salicylaldehyde derivative (gabapentsal; [2-(1-(((2-hydroxybenzylidene) amino) methyl) cyclohexyl) acetic acid]; GPS) in well-established mouse models of nociceptive pain, inflammatory edema, and pyrexia at doses of 25-100 mg/kg." | 8.02 | Pharmacological evaluation of the gabapentin salicylaldehyde derivative, gabapentsal, against tonic and phasic pain models, inflammation, and pyrexia. ( Ahmad, N; Akbar, S; Amin, MU; Islam, NU; Khurram, M; Sewell, RDE; Shahid, M; Subhan, F; Ullah, I; Ullah, N; Ullah, R, 2021) |
| " essential oil (AEO) on ovalbumin (OVA)-induced allergic rhinitis (AR) in rats." | 7.96 | Protective effect of Asarum sieboldii essential oil on ovalbumin induced allergic rhinitis in rat. ( Kang, H; Zhang, Z, 2020) |
| " Pretreatment with perampanel dose-dependently attenuated the induction of scratching, a behavior typically associated with pruritus, by intradermal administration of the pruritogen chloroquine." | 7.96 | Perampanel attenuates scratching behavior induced by acute or chronic pruritus in mice. ( Funahashi, H; Haruta-Tsukamoto, A; Ishida, Y; Miyahara, Y; Nishimori, T, 2020) |
| " The aim of this study was to test the role of histamine 2 receptors and histamine 4 receptors in the imiquimod-induced psoriasis-like skin inflammation model." | 7.96 | Histamine 2 Receptor Agonism and Histamine 4 Receptor Antagonism Ameliorate Inflammation in a Model of Psoriasis. ( Bäumer, W; Brehm, R; Bruer, G; Gutzmer, R; Kietzmann, M; Langeheine, M; Rode, K; Rossbach, K; Schaper-Gerhardt, K; Wahle, K; Werfel, T, 2020) |
| " Prior studies have demonstrated that microbial histamine can ameliorate intestinal inflammation in mice." | 7.91 | Distinct roles of histamine H1- and H2-receptor signaling pathways in inflammation-associated colonic tumorigenesis. ( Engevik, MA; Fultz, RS; Gao, C; Hall, A; Major, A; Mori-Akiyama, Y; Shi, Z; Versalovic, J, 2019) |
| "Evidence points to a dual role of histamine in microglia-mediated neuroinflammation, a key pathological feature of several neurodegenerative pathologies." | 7.91 | Histamine modulates hippocampal inflammation and neurogenesis in adult mice. ( Barata-Antunes, S; Bernardino, L; Cristóvão, AC; Ferreira, R; Ferreiro, E; Santos, T; Saraiva, C; Serra-Almeida, C, 2019) |
| "Ulcerative colitis (UC) patients exhibit elevated histamine, but how histamine exacerbates disease is unclear as targeting histamine 1 receptor (H1R) or H2R is clinically ineffective." | 7.88 | Histamine drives severity of innate inflammation via histamine 4 receptor in murine experimental colitis. ( Aguiniga, LM; Barrett, TA; Brown, JB; Bryce, PJ; Carter, RG; Hsu, CL; Krier-Burris, RA; Miller, ML; Schroeder, HA; Szabo, A; Velez, TE; Wang, MY; Wechsler, JB; Wershil, BK, 2018) |
| " Ovalbumin (OVA)-induced BALB/c anaphylaxis was established to explore the antifood allergic activity of BTL-I." | 7.88 | Deep-Sea-Derived Butyrolactone I Suppresses Ovalbumin-Induced Anaphylaxis by Regulating Mast Cell Function in a Murine Model. ( Cao, MJ; Gao, YY; Lin, WX; Liu, B; Liu, GM; Liu, H; Liu, QM; Su, WJ; Xie, CL; Yang, XW, 2018) |
| "The aims of the work were to improve our knowledge of the role of H4R in melanoma proliferation and assess in vivo the therapeutic efficacy of histamine, clozapine and JNJ28610244, an H4R agonist, in a preclinical metastatic model of melanoma." | 7.85 | Histamine therapeutic efficacy in metastatic melanoma: Role of histamine H4 receptor agonists and opportunity for combination with radiation. ( Blanco, H; Cricco, GP; Herrero Ducloux, MV; Martinel Lamas, DJ; Massari, NA; Medina, VA; Nicoud, MB; Rivera, ES; Sambuco, L, 2017) |
| " Furthermore, we assessed the therapeutic effects of taurine on ovalbumin (OVA)-induced allergic rhinitis (AR) animal models." | 7.85 | The potential protective role of taurine against experimental allergic inflammation. ( Jeong, HJ; Kim, HM; Nam, SY, 2017) |
| "3mg/kg) or carvedilol (10mg/kg) was administrated orally 1h before histamine injection into animals of a histamine-induced paw edema model and orally daily for 11days into animals of a formaldehyde-induced arthritis model." | 7.85 | Carvedilol can attenuate histamine-induced paw edema and formaldehyde-induced arthritis in rats without risk of gastric irritation. ( Kamel, MM; Labib, DA; Osman, AS, 2017) |
| " In previous work with our mouse model of malaria/NTS co-infection, we showed increased gut mastocytosis and increased ileal and plasma histamine levels that were temporally associated with increased gut permeability and bacterial translocation." | 7.83 | Mast cells and histamine alter intestinal permeability during malaria parasite infection. ( Cheung, K; Lokken, KL; Luckhart, S; Pakpour, N; Potts, RA; Tiffany, CM; Tiffany, CR; Tsolis, RM, 2016) |
| "The aim of the current study was to investigate whether olopatadine and naphazoline hydrochloride reduce allergic conjunctivitis in mice through alterations in inflammation, NGF and VEGF." | 7.83 | Treatment with olopatadine and naphazoline hydrochloride reduces allergic conjunctivitis in mice through alterations in inflammation, NGF and VEGF. ( He, H; Quan, L, 2016) |
| "Intrathecally injected histamine increased incapacitation and articular edema, whereas the H1R antagonist, cetirizine, decreased both parameters." | 7.83 | Histaminergic Pharmacology Modulates the Analgesic and Antiedematogenic Effects of Spinally Injected Morphine. ( Eto, C; Fin, FE; Mascarin, L; Souza-Silva, E; Stein, T; Tonussi, CR, 2016) |
| " To confirm the histamine-binding capacity of rHa24, a histamine-binding assay was completed in vitro (ELISA) and in vivo by inhibition of allergic asthma in mice." | 7.83 | Specific histamine binding activity of a new lipocalin from Hyalomma asiaticum (Ixodidae) and therapeutic effects on allergic asthma in mice. ( Cao, J; Gong, H; Li, Z; Wang, Y; Zhang, H; Zhou, J; Zhou, Y, 2016) |
| "The commercially available alpha-asarone injections (CA-ARE) were frequently found to cause severe anaphylactic reactions by the solubilizer contained in the formulation such as polysorbate 80 and propylene glycol." | 7.81 | Systemic delivery of alpha-asarone with Kolliphor HS 15 improves its safety and therapeutic effect on asthma. ( Gong, T; Li, J; Li, M; Lu, H; Zhang, Z, 2015) |
| "Tramadol-induced seizures might be pathologically associated with serotonin syndrome." | 7.81 | Brain serotonin content regulates the manifestation of tramadol-induced seizures in rats: disparity between tramadol-induced seizure and serotonin syndrome. ( Fujimoto, Y; Funao, T; Mori, T; Nishikawa, K; Suehiro, K; Takahashi, R, 2015) |
| "Histamine, acting centrally as a neurotransmitter, evokes a reversal of hemorrhagic hypotension in rats due to the activation of the sympathetic and the renin-angiotensin systems as well as the release of arginine vasopressin and proopiomelanocortin-derived peptides." | 7.81 | Centrally injected histamine increases posterior hypothalamic acetylcholine release in hemorrhage-hypotensive rats. ( Altinbas, B; Jochem, J; Savci, V; Yalcin, M; Yilmaz, MS, 2015) |
| " Previous studies have reported a relationship between CCL22 and atherosclerosis and the role of histamine in this pathway." | 7.81 | CCL22/Macrophage-derived Chemokine Expression in Apolipoprotein E-deficient Mice and Effects of Histamine in the Setting of Atherosclerosis. ( Guo, X; Harada, M; Kimura, S; Nabeshima, A; Noguchi, H; Sasaguri, Y; Wang, KY; Watanabe, T; Yamada, S, 2015) |
| "Via the histamine H4 -receptor (H4 R), histamine promotes the pathogenesis of experimental allergic asthma in mice." | 7.81 | The histamine H4 -receptor (H4 R) regulates eosinophilic inflammation in ovalbumin-induced experimental allergic asthma in mice. ( Glage, S; Hartwig, C; Munder, A; Neumann, D; Schenk, H; Seifert, R; Wedekind, D, 2015) |
| "Experiments were designed to evaluate changes in the histamine release, mast cell number and neuronal damage in hippocampus induced by status epilepticus." | 7.81 | The mast cell stabilizer sodium cromoglycate reduces histamine release and status epilepticus-induced neuronal damage in the rat hippocampus. ( Orozco-Suárez, SA; Rocha, L; Santana-Gómez, CE; Valle-Dorado, MG, 2015) |
| "Ovalbumin inhalation caused early (EAR) and late asthmatic response (LAR), airway hyper-reactivity to histamine and influx of inflammatory cells into the lungs." | 7.81 | LPS exacerbates functional and inflammatory responses to ovalbumin and decreases sensitivity to inhaled fluticasone propionate in a guinea pig model of asthma. ( Broadley, KJ; Ford, WR; Kidd, EJ; Lowe, AP; Nials, AT; Thomas, RS, 2015) |
| "This study is aimed at exploring the effect of Bencycloquidium bromide (BCQB), a novel M1/M3 receptor antagonist, on mucus secretion in a murine model of allergic rhinitis (AR)." | 7.81 | Bencycloquidium bromide inhibits nasal hypersecretion in a rat model of allergic rhinitis. ( Huang, J; Li, J; Long, R; Meng, L; Peng, L; Zhou, Y; Zhu, S, 2015) |
| "Histamine is a biogenic amine that is widely distributed and has multiple functions, but the role it plays in acute myocardial infarction (AMI) remains unclear." | 7.81 | Histamine deficiency exacerbates myocardial injury in acute myocardial infarction through impaired macrophage infiltration and increased cardiomyocyte apoptosis. ( Chen, J; Deng, L; Ding, S; Ge, J; Hong, T; Huang, Z; Jia, J; Lin, J; Wang, TC; Yang, X; Zou, Y, 2015) |
| "Postcolitis rats displayed a higher number of colonic mast cells, excessive histamine release and significantly enhanced VMRs." | 7.80 | Histamine H4 and H1 receptors contribute to postinflammatory visceral hypersensitivity. ( De Man, JG; De Winter, BY; Deiteren, A; Moreels, TG; Pelckmans, PA; Ruyssers, NE, 2014) |
| "To determine whether histamine cells are altered in human narcolepsy with cataplexy and in animal models of this disease." | 7.79 | Greatly increased numbers of histamine cells in human narcolepsy with cataplexy. ( Cornford, M; John, J; McGregor, R; Nishino, S; Ohtsu, H; Ramanathan, L; Sakai, N; Siegel, JM; Stone, C; Thannickal, TC; Yamanaka, A, 2013) |
| "We counted the number of hypothalamic neurons producing orexin, melanin-concentrating hormone, and histamine in 7 narcolepsy patients and 12 control subjects using stereological techniques." | 7.79 | Increase of histaminergic tuberomammillary neurons in narcolepsy. ( Baumann, CR; Gavrilov, YV; Haybaeck, J; Mignot, E; Reddy, H; Scammell, TE; Valko, PO; Yamamoto, M, 2013) |
| "Curcumin, a phytochemical present in turmeric, rhizome of Curcuma longa, has been shown to have a wide variety of pharmacological activities including anti-inflammatory, anti-allergic and anti-asthmatic properties." | 7.79 | Intranasal curcumin and its evaluation in murine model of asthma. ( Chauhan, PS; Chawla, R; Dash, D; Kumar, JP; Kumari, S; Singh, M; Singh, R, 2013) |
| "Wuling mycelia can delay the kindling and ameliorate the ability of learning in rats with pentylenetetrazole-induced epilepsy and the enhancement of neuronal histamine activity may be one of possible mechanisms." | 7.78 | [Effects of Wuling mycelia on pentylenetetrazole-induced epilepsy in rats]. ( Chen, GF; Hu, XY; Ren, GL; Zhang, LS, 2012) |
| "In the present study, the efficacy of β-sitosterol isolated from an n-butanol extract of the seeds of the plant Moringa oleifera (Moringaceae) was examined against ovalbumin-induced airway inflammation in guinea pigs." | 7.77 | Suppression of ovalbumin-induced Th2-driven airway inflammation by β-sitosterol in a guinea pig model of asthma. ( Mahajan, SG; Mehta, AA, 2011) |
| "Histamine and histamine receptors are found in atherosclerotic lesions, and their signaling and subsequent proatherogenic or proinflammatory gene expression are involved in atherogenesis." | 7.77 | Histamine deficiency decreases atherosclerosis and inflammatory response in apolipoprotein E knockout mice independently of serum cholesterol level. ( Ding, Y; Guo, X; Hirano, K; Kato, S; Kohno, K; Murata, Y; Ohtsu, H; Sasaguri, Y; Shimajiri, S; Tanimoto, A; Tsutsui, M; Wang, KY; Watanabe, T; Yamada, S, 2011) |
| "The present study explored the interaction between histaminergic and opioidergic systems at the level of the hippocampus in modulation of orofacial pain by intra-hippocampal microinjections of histamine, pyrilamine (an antagonist of histamine H(1) receptors), ranitidine (an antagonist of histamine H(2) receptors), morphine (an opioid receptor agonist) and naloxone (an opioid receptor antagonist) in separate and combined treatments." | 7.77 | Interaction between histamine and morphine at the level of the hippocampus in the formalin-induced orofacial pain in rats. ( Erfanparast, A; Farshid, AA; Khalilzadeh, E; Tamaddonfard, E, 2011) |
| " The aim of this study was to evaluate the effects of TQ on ovalbumin (OVA)-induced allergic conjunctivitis (AC) in Balb/c." | 7.77 | Ameliorative effect of thymoquinone on ovalbumin-induced allergic conjunctivitis in Balb/c mice. ( Asim, MB; Hayat, K; Li, M; Nawaz, M; Sun, N; Zhang, L, 2011) |
| "The aim of this study was to evaluate the therapeutic efficacy of tolvaptan, a vasopressin V(2) receptor antagonist, on edema in two rat models: 1) histamine-induced vascular hyperpermeability of the dorsal skin and 2) carrageenan-induced paw edema." | 7.77 | Anti-edematous effects of tolvaptan in experimental rodent models. ( Fujiki, H; Miyazaki, T; Ohmoto, K; Sakamoto, Y; Yamashita, T, 2011) |
| "To elucidate the ocular pharmacological properties of bepotastine besilate, a selective histamine H(1) receptor antagonist, when compared with other histamine H(1) receptor antagonists, using guinea pig allergic conjunctivitis models and in vitro models of eosinophil recruitment and mast cell membrane stabilization." | 7.76 | Bepotastine besilate, a highly selective histamine H(1) receptor antagonist, suppresses vascular hyperpermeability and eosinophil recruitment in in vitro and in vivo experimental allergic conjunctivitis models. ( Atsumi, I; Fujii, A; Iemura, M; Kida, T; Sakai, O; Sakaki, H; Wada, T, 2010) |
| " In the present study, the effect of repeated administration of histamine on amnesia induced by post-training administration of the drug was examined." | 7.76 | Repeated histamine pretreatment decreased amnesia induced by post-training administration of the drug in a step-down inhibitory avoidance test in mice. ( Ahmadi, S; Malekmohammadi, N; Zarrindast, MR, 2010) |
| "Both manual acupuncture and histamine injection of ST 36 can relieve pain in AIA rats, which may be closely related to its effect in activating mast cells in acupoint area." | 7.76 | [Acupoint-injection of histamine induced analgesic effect in acute adjuvant-induced-arthritis rats]. ( Ding, GH; Huang, M; Xie, YY, 2010) |
| "Histamine has a positive inotropic effect on ventricular myocardium and stimulation of histamine H₂ receptors increases the intracellular cAMP level via Gs protein, as dose stimulation of β-adrenergic receptors, and worsens heart failure." | 7.76 | A histamine H₂ receptor blocker ameliorates development of heart failure in dogs independently of β-adrenergic receptor blockade. ( Asakura, M; Asanuma, H; Fujita, M; Kim, J; Kitakaze, M; Komamura, K; Minamino, T; Sanada, S; Sasaki, H; Sugimachi, M; Takahama, H; Takashima, S; Wakeno, M, 2010) |
| "This study aimed to investigate the effect of piperine on airway hyperresponsiveness, pulmonary eosinophilic infiltration, various immune cell phenotypes, Th2 cytokine production, immunoglobulin E and histamine production in a murine model of asthma." | 7.75 | Piperine inhibits eosinophil infiltration and airway hyperresponsiveness by suppressing T cell activity and Th2 cytokine production in the ovalbumin-induced asthma model. ( Kim, SH; Lee, YC, 2009) |
| "Combination therapy blocking both PAF and histamine markedly reduces the severity of peanut-induced anaphylaxis, and thus it may be a potential life-saving therapeutic approach in peanut and, likely, other food-induced anaphylaxis." | 7.75 | Concurrent blockade of platelet-activating factor and histamine prevents life-threatening peanut-induced anaphylactic reactions. ( Arias, K; Baig, M; Chu, D; Colangelo, M; Coyle, A; Goncharova, S; Jordana, M; Vadas, P; Walker, T; Waserman, S, 2009) |
| "Effects of quercetin inhalation on immediate (IAR), late-phase (LAR) and late late-phase (LLAR) asthmatic responses by exposure to aerosolized-ovalbumin (AOA) (2w/v% in saline, inhalation for 3 min) were studied in conscious guinea-pigs sensitized with AOA." | 7.74 | Quercetin inhalation inhibits the asthmatic responses by exposure to aerosolized-ovalbumin in conscious guinea-pigs. ( Choi, HH; Kim, CJ; Lee, JY; Moon, H; Moon, HJ; Sim, SS, 2008) |
| "The contribution of the novel histamine H(4) receptor to histaminergic and allergic pruritus was investigated." | 7.74 | Histamine H4 receptor antagonists are superior to traditional antihistamines in the attenuation of experimental pruritus. ( Desai, PJ; Dunford, PJ; Karlsson, L; McQueen, D; Thurmond, RL; Williams, KN, 2007) |
| "Adenosine, an important signaling molecule in asthma, produces bronchoconstriction in asthmatics." | 7.73 | A novel A1 adenosine receptor antagonist, L-97-1 [3-[2-(4-aminophenyl)-ethyl]-8-benzyl-7-{2-ethyl-(2-hydroxy-ethyl)-amino]-ethyl}-1-propyl-3,7-dihydro-purine-2,6-dione], reduces allergic responses to house dust mite in an allergic rabbit model of asthma. ( Batra, VK; Borron, P; Mustafa, SJ; Nadeem, A; Obiefuna, PC; Wilson, CN, 2005) |
| "The aims of our study were to assess whether the increased oxidative stress in experimental otitis media with effusion (OME) induced by histamine was reflected erythrocytes and middle ear effusion fluid by lipid peroxidation; to survey the alterations in antioxidant enzyme activities in experimental OME; and to determine the effect of dantrolene on this oxidative stress." | 7.73 | Effect of dantrolene on lipid peroxidation, lutathione and glutathione-dependent enzyme activities in experimental otitis media with effusion in guinea pigs. ( Aktan, B; Buyukokuroglu, ME; Elmastas, M; Taysi, S; Ucuncu, H, 2005) |
| "Pleurisy was induced by carrageenan (Cg, 1%), bradykinin (BK, 10 nmol), histamine (HIS, 1 micromol) or substance P (PS, 20 nmol) administered by intrapleural route (ipl." | 7.73 | Antiinflammatory effects of Tacrolimus in a mouse model of pleurisy. ( Fröde, TS; Medeiros, YS; Pereira, R, 2006) |
| " Previously, it is reported that a high dose of L-97-1, a water-soluble, small molecule adenosine A(1) receptor antagonist, blocks early and late allergic responses, and bronchial hyper-responsiveness to histamine in a hyper-responsive rabbit model of allergic asthma." | 7.73 | Adenosine A1 receptor antagonist versus montelukast on airway reactivity and inflammation. ( Mustafa, SJ; Nadeem, A; Obiefuna, PC; Wilson, CN, 2006) |
| "In our model of asthma, guinea pigs were made sensitive with ovalbumine (OVA), a protein extracted from the white of egg, and provoked in a way repeated with aerosol challenge of OVA for the group OVA (1 challenge a day during six days)." | 7.73 | [Study of cellularity in bronchoalveolar fluid and bronchial reactivity to histamine in a model of asthma in guinea pig]. ( Aubier, M; Boczkowski, J; Lanone, S; Ouksel, H; Pretrolani, M; Samb, A, 2006) |
| "The present work was done to investigate the possible effects of thymoquinone on acetic acid-induced colitis in rats." | 7.72 | Thymoquinone protects against experimental colitis in rats. ( Mahgoub, AA, 2003) |
| "The study was undertaken to examine the involvement of the renin-angiotensin system in the reversal by endogenous central histamine of critical haemorrhagic hypotension in anaesthetised Wistar rats." | 7.72 | Involvement of the renin-angiotensin system in endogenous central histamine-induced reversal of critical haemorrhagic hypotension in rats. ( Jochem, J, 2004) |
| "An increase in endogenous central histamine concentrations, after loading with histamine precursor L-histidine or inhibition of histamine N-methyltransferase (HNMT) activity, produces the reversal of critical hypotension with improvement in survival of haemorrhage-shocked rats." | 7.72 | Involvement of proopiomenalocortin-derived peptides in endogenous central histamine-induced reversal of critical haemorrhagic hypotension in rats. ( Jochem, J, 2004) |
| "The aims of this study were: (a) to assess whether the increased oxidative stress in otitis media with effusion (OME) induced in guinea pigs by histamine injection into the middle ear cavity is reflected by lipid peroxidation in erythrocytes, plasma, and middle ear effusion fluid; (b) to survey the alterations of oxidant and antioxidant enzyme activities in experimental OME; and (c) to determine the effects of melatonin and methylprednisolone on this oxidative stress." | 7.72 | Protective effect of melatonin on experimental otitis media with effusion in guinea pigs. ( Aktan, B; Akyuz, M; Altas, E; Buyukokuroglu, ME; Ozabacigil, F; Ucuncu, H, 2004) |
| "We prepared a model of experimental peritonitis by introducing Escherichia coli into the peritoneal cavity of the histamine-deficient mice generated by a disruption of the gene for histidine decarboxylase (HDC), the unique histamine-synthesizing enzyme." | 7.71 | Accelerated clearance of Escherichia coli in experimental peritonitis of histamine-deficient mice. ( Doi, H; Hori, Y; Kuramasu, A; Kurokawa, Y; Makabe-Kobayashi, Y; Nagy, A; Nihei, Y; Ohtsu, H; Sakurai, E; Satomi, S; Terui, T; Watanabe, T, 2002) |
| " coli-induced acute infectious peritonitis in rats previously depleted on mast cells of peritoneal cavity the replacing effects of various doses of exogenous histamine, serotonin and heparin and their complex on leukocytic reaction of inflammatory focus and blood were studied." | 7.71 | [Modulating effects of exogenous histamine, serotonin, and heparin on leukocytic reaction during inflammation]. ( Klymenko, MO; Pyshnov, HIu, 2001) |
| "In the air pouch-type allergic inflammation in rats, we reported that a sustained histamine production in the late phase is induced by a cytokine-like factor, named histamine-production-increasing factor (HPIF) (1)." | 7.70 | Increase in histamine production by inflammatory exudate in the chronic phase of allergic inflammation in rats. ( Hirasawa, N; Mue, S; Ohuchi, K; Oikawa, S; Shiraishi, M, 1998) |
| " When the eyes were treated with histamine, a complement C5a analogue peptide and hydrogen peroxide, typical signs of uveitis were produced." | 7.70 | Arterially perfused eye model of uveitis. ( Sanderson, SD; Shiels, IA; Taylor, SM, 1999) |
| "0 mg ovalbumin (OVA) by gavage every day for 9 weeks, and active systemic anaphylaxis (ASA) was induced by intraperitoneal injection of OVA." | 7.70 | Induction of active systemic anaphylaxis by oral sensitization with ovalbumin in mast-cell-deficient mice. ( Akiyama, H; Goda, Y; Okunuki, H; Sakushima, J; Sawada, JI; Teshima, R; Toyoda, M, 2000) |
| "Acetylshikonin, a naphthoquinone isolated from the Chinese herb medicine, tzu ts'ao, was demonstrated to inhibit the polymyxin B-induced hind-paw edema in normal as well as in adrenalectomized mice." | 7.69 | Inhibition of hind-paw edema and cutaneous vascular plasma extravasation in mice by acetylshikonin. ( Chang, LC; Kuo, SC; Raung, SL; Wang, JP, 1995) |
| "Daily oral administration of cimetidine or omeprazole markedly accelerated the healing of acetic acid-induced gastric ulcers in rats with a limited food intake time." | 7.69 | Cimetidine and omeprazole accelerate gastric ulcer healing by an increase in gastrin secretion. ( Inaguma, K; Ito, M; Segami, T; Suzuki, Y, 1994) |
| "The effects of the histamine precursor, L-histidine, were examined in the rat kindling model of epilepsy." | 7.69 | Biphasic action of the histamine precursor L-histidine in the rat kindling model of epilepsy. ( Koshino, Y; Nakamura, M; Shiraishi, J; Wada, Y, 1996) |
| "The role of substance P in experimental allergic conjunctivitis induced by egg albumin was investigated with guinea pigs." | 7.69 | Role of substance P in experimental allergic conjunctivitis in guinea pigs. ( Fujiwara, R; Izushi, K; Kamei, C; Ohishi, H; Sugimoto, Y; Takada, M; Yamaji, M, 1997) |
| "The role of indomethacin-induced peptic ulceration in gastric acid secretion was investigated using albino rats of Wistar strain in early, mid and late pregnancy." | 7.68 | Role of indomethacin-induced peptic ulceration in gastric acid secretion in pregnant rats. ( Bolarinwa, Y; Evbuomwan, MI, 1993) |
| "Recent studies have demonstrated a connection between xanthine oxidase-generated reactive oxygen intermediates and histamine release during ischemia-reperfusion." | 7.68 | Studies on the relationship between xanthine oxidase and histamine release during intestinal ischemia-reperfusion. ( Bakó, L; Boros, M; Kaszaki, J; Nagy, S, 1992) |
| "The role of histamine in neutrophil infiltration and vascular permeability response in carrageenin air pouch inflammation in rats was examined." | 7.68 | Downward regulation of neutrophil infiltration by endogenous histamine without affecting vascular permeability responses in air-pouch-type carrageenin inflammation in rats. ( Hirasawa, N; Mue, S; Ohuchi, K; Tsurufuji, S; Watanabe, M, 1991) |
| "We studied the effects of coenzyme Q10 (CoQ10) on pulmonary function and chemical mediators in a canine model of hemorrhagic shock." | 7.68 | Effects of coenzyme Q10 in hemorrhagic shock. ( Yamada, M, 1990) |
| "Healing of duodenal ulcers induced by indomethacin + histamine was investigated in rats." | 7.67 | Healing process of duodenal ulcers induced by indomethacin plus histamine in rats. ( Niida, H; Okabe, S; Okada, M; Takeuchi, K, 1989) |
| "The role of the central histaminergic system in depression was studied by using swimming despair test in mice - a behavioural model of depression." | 7.67 | Role of central histaminergic mechanism in behavioural depression (swimming despair) in mice. ( Dhawan, KN; Gulati, A; Gupta, GP; Nath, C, 1988) |
| " To separately evaluate the ability of isoproterenol, a beta-adrenergic agonist, to prevent mediator release and anaphylactic shock, as well as to reverse the cardiopulmonary manifestations of systemic anaphylaxis, we administered a continuous infusion of isoproterenol before and during canine anaphylactic shock." | 7.67 | Prevention of canine anaphylaxis with isoproterenol. ( Bleecker, ER; Kagey-Sobotka, A; Lichtenstein, LM; Silverman, HJ; Smith, PL; Taylor, WR, 1986) |
| "Praomys (Mastomys) natalensis, an African rodent ranging in size between a mouse and a rat, is more susceptible to the induction of duodenal ulcers by constant infusion of exogenous histamine through an osmotic minipump implanted subcutaneously than other rodent species tested such as mouse, rat, or guinea-pig." | 7.66 | Praomys (Mastomys) natalensis: animal model for study of histamine-induced duodenal ulcers. ( Hosoda, S; Ikedo, H; Saito, T, 1981) |
| "Insight into the pathogenesis and etiology of experimental duodenal ulceration was sought by studying the modulation of this disease in rats by selective vagotomy, chemical sympathectomy, histamine depletion, histamine H-2 receptor antagonists (eg, metiamide, cimetidine), or endocrine ablations." | 7.66 | Pathogenesis of duodenal ulceration produced by cysteamine or propionitrile: influence of vagotomy, sympathectomy, histamine depletion, H-2 receptor antagonists and hormones. ( Haith, LR; Reynolds, ES; Szabo, S, 1979) |
| "Histamine release could be shown in 50% of the dogs suffering from acute haemorrhagic pancreatitis in Pfeffer's preparation." | 7.66 | Histamine and pancreatitis: increase of plasma histamine levels in dogs with Pfeffer preparation and influence of aminoguanidine on the survival time. ( Kresse, U; Lange, E; Lorenz, W; Maroske, D; Neuhaus, H; Reimann, HJ; Schult, H; Schwarz, B, 1978) |
| "The effects of cimetidine, a new histamine H2-receptor antagonist, on the development of experimental gastric and duodenal ulcers were studied." | 7.65 | Effects of cimetidine, a histamine H2-receptor antagonist, on various experimental gastric and duodenal ulcers. ( Okabe, S; Takagi, K; Takeuchi, K; Urushidani, T, 1977) |
| "Histamine is a well-characterized neuromodulator that follows a circadian rhythm, regulates IOP and modulates retinal circuits and vision." | 6.72 | Novel Insight of Histamine and Its Receptor Ligands in Glaucoma and Retina Neuroprotection. ( Lanzi, C; Lucarini, L; Masini, E; Sgambellone, S, 2021) |
| "Histamine is a ubiquitous inflammatory mediator intimately associated with the pathology of allergy." | 6.46 | The role of histamine in asthma. ( Dunford, PJ; Holgate, ST, 2010) |
| "Many studies show that the number of cognitive impairmentscan be reduced by antagonists of the histamine H3 receptor (H3R)." | 5.91 | Amelioration of cognition impairments in the valproic acid-induced animal model of autism by ciproxifan, a histamine H3-receptor antagonist. ( Esmaeilpour, K; Sepehri, G; Sheibani, V; Shekari, MA; Taheri, F, 2023) |
| "Bronchial asthma is a chronic lung disorder, that affects an estimated 262 million people worldwide, thereby, causing a large socio-economic burden." | 5.72 | Orally administered solasodine, a steroidal glycoalkaloid, suppresses ovalbumin-induced exaggerated Th2-immune response in rat model of bronchial asthma. ( Arora, P; Chellappan, DK; Dua, K; Gupta, G; Nainwal, LM; Oliver, BG; Singh, SK, 2022) |
| "Otitis media with effusion is a clinical manifestation characterised by inflammation of middle-ear mucosa." | 5.48 | The anti-inflammatory effects of erythromycin, clarithromycin, azithromycin and roxithromycin on histamine-induced otitis media with effusion in guinea pigs. ( Aktan, B; Ersoy, B; Kilic, K; Sakat, MS; Sipal, S, 2018) |
| "Histamine plays an important role in physiology and pathophysiology of cardiovascular system." | 5.48 | Experimental autoimmune myocarditis in rats and therapeutic histamine H1 - H4 receptor inhibition. ( Fogel, WA; Gola, J; Kobos, J; Kraszewska, K; Mazurek, U; Mussur, M; Stark, H; Stasiak, A, 2018) |
| "Allergic rhinitis is a common heterogeneous chronic upper airway disorder and is an IgE-mediated inflammation characterized by one or more nasal symptoms such as sneezing, itching, nasal discharge, rhinorrhea, post nasal drainage and nasal blockage." | 5.46 | Skullcapflavone II attenuates ovalbumin-induced allergic rhinitis through the blocking of Th2 cytokine production and mast cell histamine release. ( Bui, TT; Chai, OH; Piao, CH; Song, CH, 2017) |
| "Histamine was able also to potentiate in vivo the anti-tumoral effect of radiation, increasing the exponential tumor doubling time." | 5.42 | Enhancement of ionizing radiation response by histamine in vitro and in vivo in human breast cancer. ( Balestrasse, KB; Blanco, H; Cortina, JE; Cremaschi, GA; Martinel Lamas, DJ; Medina, VA; Rivera, ES; Sterle, HA; Valli, E; Ventura, C, 2015) |
| "We found that pronounced hyperlipidemia-induced atherosclerotic progression occurred in HH1R/apoE-DKO mice, but in HH2R/apoE-DKO mice less atherosclerosis, despite pro-atherogenic serum cholesterol levels compared with apoE-KO mice." | 5.42 | Novel function of histamine signaling in hyperlipidemia-induced atherosclerosis: Histamine H1 receptors protect and H2 receptors accelerate atherosclerosis. ( Sasaguri, Y; Tanimoto, A; Wang, KY; Yamada, S, 2015) |
| "Piperine (PIP) has been reported to exhibit anti-inflammatory, anti-histaminic, and immunomodulatory activities; however, its antiallergic profile has not been studied." | 5.42 | Antiallergic effect of piperine on ovalbumin-induced allergic rhinitis in mice. ( Aswar, M; Aswar, U; Chepurwar, S; Shintre, S, 2015) |
| "Kaempferol (KP) is a major compound of Naju Jjok (Polygonum tinctorium Lour." | 5.39 | Evaluation of the effect of kaempferol in a murine allergic rhinitis model. ( Han, NR; Jeong, HJ; Kim, HM; Kim, MJ; Oh, HA, 2013) |
| "Histamine has an important role in regulation of immune response which is mediated by differential expression of four distinct receptors, H1R-H4R." | 5.34 | Histamine 4 receptor activation induces recruitment of FoxP3+ T cells and inhibits allergic asthma in a murine model. ( Center, DM; Cross, L; Cruikshank, WW; Green, DS; Kornfeld, H; McAllister, B; Morgan, RK, 2007) |
| " Blood catecholamines (CA), histamine (H), serotonin (S), 11-oxycorticosteroids (11-OCS) were studied in 100 patients with acute hepatitis B and C." | 5.12 | [Optimization of hepatoprotective therapy of viral hepatitis with consideration of neuromediatory link of pathogenesis]. ( Maleev, VV; Shoshin, AA; Sitnikov, IG, 2006) |
| "Histamine is an immune modulator, neuroprotective, and remyelinating agent, beneficially acting on skeletal muscles and promoting anti-inflammatory features in amyotrophic lateral sclerosis (ALS) microglia." | 5.01 | Histaminergic transmission slows progression of amyotrophic lateral sclerosis. ( Amadio, S; Apolloni, S; Cavallaro, S; Fabbrizio, P; Ferri, A; Latagliata, EC; Madaro, L; Morello, G; Proietti, D; Puglisi-Allegra, S; Salvatori, I; Spampinato, AG; Volonté, C, 2019) |
| "The histamine H4 receptor is expressed preferentially on immune cells, indicating a possible role of the H4 receptor in inflammation." | 4.86 | Does the histamine H4 receptor have a pro- or anti-inflammatory role in murine bronchial asthma? ( Beermann, S; Neumann, D; Seifert, R, 2010) |
| "In a series of studies on histaminergic functions in the hypothalamus, probes to manipulate activities of histaminergic neuron systems were applied to assess its physiologic and pathophysiologic implications using non-obese normal and Zucker obese rats, an animal model of genetic obesity." | 4.79 | Hypothalamic neuronal histamine: implications of its homeostatic control of energy metabolism. ( Kurokawa, M; Sakata, T; Yoshimatsu, H, 1997) |
| " The kallikrien-kinin system and eicosanoids were the main mediators responsible for plasma exudation in carrageenin-induced rat pleurisy, while histamine, PAF and the complement system could be the main mediators involved in the vascular permeability increase to cause plasma exudation into the pleural cavity in zymosan-induced rat pleurisy." | 4.79 | [Analysis of chemical mediators involved in acute inflammatory reaction with the rat pleurisy model]. ( Oh-ishi, S, 1997) |
| "Hydrogen-rich water has a significant protective effect on OGD/R-causing HT22 cell injury, and the mechanism may be related to the inhibition of autophagy." | 4.40 | Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19. ( , 2023) |
| "OVA treatment successfully induced AR model in mice with significantly increased sneezing and rubbing frequency, elevated levels of serum histamine, IL-1β, IL-10 and OVA-specific IgE." | 4.31 | Bufotalin ameliorates ovalbumin-induced allergic rhinitis by restoring the Tregs. ( Ji, Q; Li, L; Ren, S, 2023) |
| " The effect of the DPP4 inhibitor sitagliptin on the effector phase of allergic rhinitis (AR) in ovalbumin (OVA)-sensitized mice and on mast cell degranulation in vitro was assessed." | 4.31 | DPP4 Inhibitor Sitagliptin Reduces Inflammatory Responses and Mast Cell Activation in Allergic Rhinitis. ( Sun, X; Xu, Y; Zhou, J, 2023) |
| " We investigated AR-related behavior (sneezing and nose rubbing), as well as total immunoglobulin E (IgE), histamine, interleukin-4 (IL-4), leukotriene (LT) B4 and LTC4 levels, and gene expression of CysLT1R, HRH1, and MUC5a." | 4.12 | Effect of Temperature and Humidity on the Allegro-inflammatory Factors and Allergic Rhinitis-related Behavior. ( Liuo, Y; Mehrabi Nasab, E; Yonghua, S, 2022) |
| "To study the therapeutic potential of Antileukotriene drug- Camellia sinensis extract co-formulation on histamine induced asthma in guinea pigs." | 4.02 | Therapeutic Potential of Antileukotriene Drug- ( Kulkarni, GT; Kumar, Y; Singh, N, 2021) |
| " In mice, while allergen-provoked acute itch is mediated by the mast cell-histamine axis in steady state, AD-associated inflammation renders this pathway dispensable." | 4.02 | A basophil-neuronal axis promotes itch. ( Ardeleanu, M; Baek, J; Chai, JN; Chen, Z; Dong, X; Hamilton, JD; Hsieh, CS; Hu, H; Kim, BS; Kim, S; Kubo, M; Li, F; Liu, Q; Mack, MR; Margolis, DJ; Miller, MJ; Morrison, SA; Trier, AM; Ver Heul, AM; Wang, F; Xie, Z; Xu, AZ; Yang, TB, 2021) |
| " Compared to the naïve mice, a significant increase in itch-related behaviors was observed in the CCD mice after the injection of pruritogens including histamine and BAM8-22, but not after the injection of capsaicin, although all the above agents evoked enhanced pain-related behaviors toward the injected site." | 4.02 | The role of pruriceptors in enhancing sensitivity to pruritogens in a murine chronic compression model of dorsal root ganglion. ( Fang, Y; Ma, C; Tao, J; Wang, T, 2021) |
| "Histamine is best known for its role in allergies, but it could also be involved in autoimmune diseases such as multiple sclerosis." | 4.02 | Conditional Deletions of ( Dumas, A; Mdzomba, JB; Morin, F; Pernet, V; Singh, N; Vallières, L, 2021) |
| "Histamine is known to lead to arrhythmias in the human heart." | 4.02 | Human histamine H ( Gergs, U; Griethe, K; Kirchhefer, U; Mißlinger, N; Neumann, J; Weisgut, J, 2021) |
| " The current study evaluated the pharmacological activity of gabapentin (GBP) and its salicylaldehyde derivative (gabapentsal; [2-(1-(((2-hydroxybenzylidene) amino) methyl) cyclohexyl) acetic acid]; GPS) in well-established mouse models of nociceptive pain, inflammatory edema, and pyrexia at doses of 25-100 mg/kg." | 4.02 | Pharmacological evaluation of the gabapentin salicylaldehyde derivative, gabapentsal, against tonic and phasic pain models, inflammation, and pyrexia. ( Ahmad, N; Akbar, S; Amin, MU; Islam, NU; Khurram, M; Sewell, RDE; Shahid, M; Subhan, F; Ullah, I; Ullah, N; Ullah, R, 2021) |
| " Experimental otitis media with effusion was created by intratympanic histamine injection." | 3.96 | Effect of probiotics in experimental otitis media with effusion. ( Arslan, N; Celik, H; Ibas, M; Kaytez, SK; Ocal, R; Yumusak, N, 2020) |
| " essential oil (AEO) on ovalbumin (OVA)-induced allergic rhinitis (AR) in rats." | 3.96 | Protective effect of Asarum sieboldii essential oil on ovalbumin induced allergic rhinitis in rat. ( Kang, H; Zhang, Z, 2020) |
| " Pretreatment with perampanel dose-dependently attenuated the induction of scratching, a behavior typically associated with pruritus, by intradermal administration of the pruritogen chloroquine." | 3.96 | Perampanel attenuates scratching behavior induced by acute or chronic pruritus in mice. ( Funahashi, H; Haruta-Tsukamoto, A; Ishida, Y; Miyahara, Y; Nishimori, T, 2020) |
| " The aim of this study was to test the role of histamine 2 receptors and histamine 4 receptors in the imiquimod-induced psoriasis-like skin inflammation model." | 3.96 | Histamine 2 Receptor Agonism and Histamine 4 Receptor Antagonism Ameliorate Inflammation in a Model of Psoriasis. ( Bäumer, W; Brehm, R; Bruer, G; Gutzmer, R; Kietzmann, M; Langeheine, M; Rode, K; Rossbach, K; Schaper-Gerhardt, K; Wahle, K; Werfel, T, 2020) |
| " Anti-inflammatory properties of selected synthesized compounds were studied in vivo using the histamine-, concanavalin A- and sheep erythrocytes immunization-induced mouse paw edema models." | 3.91 | Fluorine-containing lupane triterpenoid acid derivatives: Design, synthesis and biological evaluation as potential anti-inflammatory agents. ( Baranovsky, AV; Khlebnicova, TS; Lakhvich, FA; Piven, YA; Sorokina, IV; Tolstikova, TG, 2019) |
| " Prior studies have demonstrated that microbial histamine can ameliorate intestinal inflammation in mice." | 3.91 | Distinct roles of histamine H1- and H2-receptor signaling pathways in inflammation-associated colonic tumorigenesis. ( Engevik, MA; Fultz, RS; Gao, C; Hall, A; Major, A; Mori-Akiyama, Y; Shi, Z; Versalovic, J, 2019) |
| "Oral administration of E coli BL21_HTW, which is able to secrete histamine, to wild-type mice reduced lung eosinophilia and suppressed ex vivo OVA-stimulated cytokine secretion from lung cells in the OVA respiratory inflammation mouse model." | 3.91 | Bacterial secretion of histamine within the gut influences immune responses within the lung. ( Akdis, CA; Altunbulakli, C; Barcik, W; Brescó, MS; Ferstl, R; Frei, R; Groeger, D; Krawczyk, K; O'Mahony, L; Pugin, B; Rinaldi, A; Sokolowska, M; Van Elst, D; Wawrzyniak, M; Westermann, P, 2019) |
| " In this study, we developed epinastine hydrochloride-releasing daily soft contact lenses for treatment of allergic conjunctivitis and examined their in vitro and in vivo performance." | 3.91 | In vitro and in vivo performance of epinastine hydrochloride-releasing contact lenses. ( Arai, R; Fukushima, A; Hino, S; Ishida, W; Kishimoto, T; Matsunaga, T; Minami, T; Nakajima, I; Yamagami, S, 2019) |
| "Evidence points to a dual role of histamine in microglia-mediated neuroinflammation, a key pathological feature of several neurodegenerative pathologies." | 3.91 | Histamine modulates hippocampal inflammation and neurogenesis in adult mice. ( Barata-Antunes, S; Bernardino, L; Cristóvão, AC; Ferreira, R; Ferreiro, E; Santos, T; Saraiva, C; Serra-Almeida, C, 2019) |
| " The anti-inflammatory activity of synthesized compounds was tested in vivo using models of inflammation induced by concanavalin A and histamine." | 3.91 | Lupane-type conjugates with aminoacids, 1,3,4- oxadiazole and 1,2,5-oxadiazole-2-oxide derivatives: Synthesis, anti-inflammatory activity and in silico evaluation of target affinity. ( Baev, DS; Frolova, TS; Popov, SA; Semenova, MD; Shults, EE; Sorokina, IV; Tolstikova, TG; Turks, M; Zhukova, NA, 2019) |
| "Ulcerative colitis (UC) patients exhibit elevated histamine, but how histamine exacerbates disease is unclear as targeting histamine 1 receptor (H1R) or H2R is clinically ineffective." | 3.88 | Histamine drives severity of innate inflammation via histamine 4 receptor in murine experimental colitis. ( Aguiniga, LM; Barrett, TA; Brown, JB; Bryce, PJ; Carter, RG; Hsu, CL; Krier-Burris, RA; Miller, ML; Schroeder, HA; Szabo, A; Velez, TE; Wang, MY; Wechsler, JB; Wershil, BK, 2018) |
| " Itch responses were evoked by histamine, chloroquine, and dinitrochlorobenzene-induced contact dermatitis (CD)." | 3.88 | GPCR Kinase (GRK)-2 Is a Key Negative Regulator of Itch: l-Glutamine Attenuates Itch via a Rapid Induction of GRK2 in an ERK-Dependent Way. ( Han, MK; Im, SY; Im, YN; Kim, HK; Lee, HK; Lee, YD; Park, JS; Song, HR, 2018) |
| " Ovalbumin (OVA)-induced BALB/c anaphylaxis was established to explore the antifood allergic activity of BTL-I." | 3.88 | Deep-Sea-Derived Butyrolactone I Suppresses Ovalbumin-Induced Anaphylaxis by Regulating Mast Cell Function in a Murine Model. ( Cao, MJ; Gao, YY; Lin, WX; Liu, B; Liu, GM; Liu, H; Liu, QM; Su, WJ; Xie, CL; Yang, XW, 2018) |
| "Geraniol is a monoterpene alcohol that has anti-fungal, anti-cancer and anti-nociceptive properties, but its anti-allergic rhinitis (AR) property is unclear." | 3.88 | Geraniol suppresses proinflammatory mediators in phorbol 12-myristate 13-acetate with A23187-induced HMC-1 cells. ( Huang, Y; Ni, YH; Xu, ZM; Yang, XL, 2018) |
| "The aims of the work were to improve our knowledge of the role of H4R in melanoma proliferation and assess in vivo the therapeutic efficacy of histamine, clozapine and JNJ28610244, an H4R agonist, in a preclinical metastatic model of melanoma." | 3.85 | Histamine therapeutic efficacy in metastatic melanoma: Role of histamine H4 receptor agonists and opportunity for combination with radiation. ( Blanco, H; Cricco, GP; Herrero Ducloux, MV; Martinel Lamas, DJ; Massari, NA; Medina, VA; Nicoud, MB; Rivera, ES; Sambuco, L, 2017) |
| " Furthermore, we assessed the therapeutic effects of taurine on ovalbumin (OVA)-induced allergic rhinitis (AR) animal models." | 3.85 | The potential protective role of taurine against experimental allergic inflammation. ( Jeong, HJ; Kim, HM; Nam, SY, 2017) |
| "3mg/kg) or carvedilol (10mg/kg) was administrated orally 1h before histamine injection into animals of a histamine-induced paw edema model and orally daily for 11days into animals of a formaldehyde-induced arthritis model." | 3.85 | Carvedilol can attenuate histamine-induced paw edema and formaldehyde-induced arthritis in rats without risk of gastric irritation. ( Kamel, MM; Labib, DA; Osman, AS, 2017) |
| "Histamine H1 receptor (H1R) gene is upregulated in patients with allergic rhinitis (AR), and its expression level is strongly correlated with the severity of allergic symptoms." | 3.83 | A novel benzofuran, 4-methoxybenzofuran-5-carboxamide, from Tephrosia purpurea suppressed histamine H1 receptor gene expression through a protein kinase C-δ-dependent signaling pathway. ( Fukui, H; Kadota, T; Karmakar, S; Kashiwada, Y; Kitamura, Y; Mizuguchi, H; Mukherjee, PK; Nemoto, H; Shill, MC; Takeda, N, 2016) |
| " In previous work with our mouse model of malaria/NTS co-infection, we showed increased gut mastocytosis and increased ileal and plasma histamine levels that were temporally associated with increased gut permeability and bacterial translocation." | 3.83 | Mast cells and histamine alter intestinal permeability during malaria parasite infection. ( Cheung, K; Lokken, KL; Luckhart, S; Pakpour, N; Potts, RA; Tiffany, CM; Tiffany, CR; Tsolis, RM, 2016) |
| "The aim of the current study was to investigate whether olopatadine and naphazoline hydrochloride reduce allergic conjunctivitis in mice through alterations in inflammation, NGF and VEGF." | 3.83 | Treatment with olopatadine and naphazoline hydrochloride reduces allergic conjunctivitis in mice through alterations in inflammation, NGF and VEGF. ( He, H; Quan, L, 2016) |
| "Intrathecally injected histamine increased incapacitation and articular edema, whereas the H1R antagonist, cetirizine, decreased both parameters." | 3.83 | Histaminergic Pharmacology Modulates the Analgesic and Antiedematogenic Effects of Spinally Injected Morphine. ( Eto, C; Fin, FE; Mascarin, L; Souza-Silva, E; Stein, T; Tonussi, CR, 2016) |
| " To confirm the histamine-binding capacity of rHa24, a histamine-binding assay was completed in vitro (ELISA) and in vivo by inhibition of allergic asthma in mice." | 3.83 | Specific histamine binding activity of a new lipocalin from Hyalomma asiaticum (Ixodidae) and therapeutic effects on allergic asthma in mice. ( Cao, J; Gong, H; Li, Z; Wang, Y; Zhang, H; Zhou, J; Zhou, Y, 2016) |
| " Essential BV (eBV) was developed by removing phospholipase A2 (PLA2) and histamine to lower occurrence of allergic reaction." | 3.83 | In Vitro and In Vivo Anti-Allergic and Anti-Inflammatory Effects of eBV, a Newly Developed Derivative of Bee Venom, through Modulation of IRF3 Signaling Pathway in a Carrageenan-Induced Edema Model. ( Chung, HJ; Ha, IH; Kim, EJ; Kim, MJ; Kim, MR; Kim, WK; Koh, W; Lee, IH; Lee, J; Lee, JW; Lee, SK; Lee, YJ; Shin, JS, 2016) |
| "The commercially available alpha-asarone injections (CA-ARE) were frequently found to cause severe anaphylactic reactions by the solubilizer contained in the formulation such as polysorbate 80 and propylene glycol." | 3.81 | Systemic delivery of alpha-asarone with Kolliphor HS 15 improves its safety and therapeutic effect on asthma. ( Gong, T; Li, J; Li, M; Lu, H; Zhang, Z, 2015) |
| " Since histamine affects inflammatory reactions and immune responses, we investigated effects of intraperitoneal administration of histamine on peritonitis induced by mechanical scraping in mice." | 3.81 | Suppression of peritoneal thickening by histamine in a mouse model of peritoneal scraping. ( Adachi, N; Iwamoto, N; Liu, K; Mabuchi, H; Motoki, A; Ninomiya, K; Nishibori, M; Yorozuya, T, 2015) |
| "Tramadol-induced seizures might be pathologically associated with serotonin syndrome." | 3.81 | Brain serotonin content regulates the manifestation of tramadol-induced seizures in rats: disparity between tramadol-induced seizure and serotonin syndrome. ( Fujimoto, Y; Funao, T; Mori, T; Nishikawa, K; Suehiro, K; Takahashi, R, 2015) |
| "Histamine, acting centrally as a neurotransmitter, evokes a reversal of hemorrhagic hypotension in rats due to the activation of the sympathetic and the renin-angiotensin systems as well as the release of arginine vasopressin and proopiomelanocortin-derived peptides." | 3.81 | Centrally injected histamine increases posterior hypothalamic acetylcholine release in hemorrhage-hypotensive rats. ( Altinbas, B; Jochem, J; Savci, V; Yalcin, M; Yilmaz, MS, 2015) |
| " Previous studies have reported a relationship between CCL22 and atherosclerosis and the role of histamine in this pathway." | 3.81 | CCL22/Macrophage-derived Chemokine Expression in Apolipoprotein E-deficient Mice and Effects of Histamine in the Setting of Atherosclerosis. ( Guo, X; Harada, M; Kimura, S; Nabeshima, A; Noguchi, H; Sasaguri, Y; Wang, KY; Watanabe, T; Yamada, S, 2015) |
| "Via the histamine H4 -receptor (H4 R), histamine promotes the pathogenesis of experimental allergic asthma in mice." | 3.81 | The histamine H4 -receptor (H4 R) regulates eosinophilic inflammation in ovalbumin-induced experimental allergic asthma in mice. ( Glage, S; Hartwig, C; Munder, A; Neumann, D; Schenk, H; Seifert, R; Wedekind, D, 2015) |
| " Treatment with TAPP-CZ (10 and 30 µg/kg in nostril) showed significant attenuation in OVA-induced alterations of the nasal (number of nasal rubbing and sneezing), biochemical markers (serum IgE and histamine), haematological, morphological (relative organ weight of spleen and lung) and histopathological (nasal mucosa and spleen) parameters." | 3.81 | Anti-allergic effect of intranasal administration of type-A procyanidin polyphenols based standardized extract of cinnamon bark in ovalbumin sensitized BALB/c mice. ( Aswar, UM; Kandhare, AD; Mohan, V; Thakurdesai, PA, 2015) |
| "Passive systemic anaphylaxis was induced in female and male mice by using histamine, as well as IgE or IgG receptor aggregation." | 3.81 | Estrogen increases the severity of anaphylaxis in female mice through enhanced endothelial nitric oxide synthase expression and nitric oxide production. ( Bandara, G; Desai, A; Gilfillan, AM; Hox, V; Metcalfe, DD; Olivera, A, 2015) |
| "Experiments were designed to evaluate changes in the histamine release, mast cell number and neuronal damage in hippocampus induced by status epilepticus." | 3.81 | The mast cell stabilizer sodium cromoglycate reduces histamine release and status epilepticus-induced neuronal damage in the rat hippocampus. ( Orozco-Suárez, SA; Rocha, L; Santana-Gómez, CE; Valle-Dorado, MG, 2015) |
| "Ovalbumin inhalation caused early (EAR) and late asthmatic response (LAR), airway hyper-reactivity to histamine and influx of inflammatory cells into the lungs." | 3.81 | LPS exacerbates functional and inflammatory responses to ovalbumin and decreases sensitivity to inhaled fluticasone propionate in a guinea pig model of asthma. ( Broadley, KJ; Ford, WR; Kidd, EJ; Lowe, AP; Nials, AT; Thomas, RS, 2015) |
| "This study is aimed at exploring the effect of Bencycloquidium bromide (BCQB), a novel M1/M3 receptor antagonist, on mucus secretion in a murine model of allergic rhinitis (AR)." | 3.81 | Bencycloquidium bromide inhibits nasal hypersecretion in a rat model of allergic rhinitis. ( Huang, J; Li, J; Long, R; Meng, L; Peng, L; Zhou, Y; Zhu, S, 2015) |
| "Asthma, a common disorder that affects >250 million people worldwide, is defined by exaggerated bronchoconstriction to inflammatory mediators including acetylcholine (ACh), bradykinin and histamine-also termed airway hyper-responsiveness." | 3.81 | A fungal protease allergen provokes airway hyper-responsiveness in asthma. ( Balenga, NA; Chan, EC; Druey, KM; Jude, J; Klichinsky, M; Laviolette, M; Panettieri, RA; Xie, Z; Zhao, M, 2015) |
| " Swiss mice were pretreated with gamma-terpinene and subjected to protocols of paw edema with different phlogistic agents such as carrageenan, prostaglandin-E2, histamine, or bradykinin." | 3.81 | Gamma-Terpinene Modulates Acute Inflammatory Response in Mice. ( Bezerra-Santos, CR; Lima, AL; Oliveira, MT; Piuvezam, MR; Ramalho, TR, 2015) |
| "Histamine is a biogenic amine that is widely distributed and has multiple functions, but the role it plays in acute myocardial infarction (AMI) remains unclear." | 3.81 | Histamine deficiency exacerbates myocardial injury in acute myocardial infarction through impaired macrophage infiltration and increased cardiomyocyte apoptosis. ( Chen, J; Deng, L; Ding, S; Ge, J; Hong, T; Huang, Z; Jia, J; Lin, J; Wang, TC; Yang, X; Zou, Y, 2015) |
| "Acute pruritus was induced in ICR mice by a single intradermal injection of histamine, 4-methylhistamine, serotonin, compound 48/80, substance P (SP), or the proteinase-activated receptor-2 (PAR-2)-activating peptide SLIGRL-NH2." | 3.80 | Sex-related differences in SLIGRL-induced pruritus in mice. ( Suwa, E; Tomono, A; Ueno, K; Yamaura, K, 2014) |
| "We examined the effect of topical thymol on IgE-dependent responses using a mast cell-dependent passive cutaneous anaphylaxis (PCA) model, as well as in vitro-cultured mast cells." | 3.80 | IgE-mediated mast cell responses are inhibited by thymol-mediated, activation-induced cell death in skin inflammation. ( Bryce, PJ; Hsu, CL; Wechsler, JB, 2014) |
| " Acute wheal responses to intradermal histamine correlated positively with birth weight in singletons (P = 0." | 3.80 | Placental restriction of fetal growth reduces cutaneous responses to antigen after sensitization in sheep. ( Bischof, RJ; Clifton, VL; Gatford, KL; Giles, LC; Heinemann, GK; Hunter, DS; Kind, KL; Liu, H; Meeusen, EN; Owens, JA; Wooldridge, AL, 2014) |
| "Postcolitis rats displayed a higher number of colonic mast cells, excessive histamine release and significantly enhanced VMRs." | 3.80 | Histamine H4 and H1 receptors contribute to postinflammatory visceral hypersensitivity. ( De Man, JG; De Winter, BY; Deiteren, A; Moreels, TG; Pelckmans, PA; Ruyssers, NE, 2014) |
| " in wistar rats 1 hr before carrageenan, dextran, histamine or serotonin, were tested in paw oedema models." | 3.80 | Peripheral antinociception and anti-inflammatory effects of sulphated polysaccharides from the alga Caulerpa mexicana. ( Benevides, NM; Bezerra, MM; Carneiro, JG; Chaves, HV; Coura, CO; de Araújo, IW; de Sousa Oliveira Vanderlei, E; Quinderé, AL; Rodrigues, JA; Souza, RB, 2014) |
| " In in vivo experiments using a rat model of hind paw oedema, CRP increased PAF-induced rat paw oedema in a dose-dependent manner, without causing the oedema itself, but it did not increase histamine and serotonin-induced paw oedema." | 3.80 | C-reactive protein specifically enhances platelet-activating factor-induced inflammatory activity in vivo. ( Ebina, K; Oe, K; Sato, A; Yamanaka, H; Yokoyama, I, 2014) |
| "R group consistently displayed a transient antigen-induced airway obstruction (AI-AO) as well as AI-AHR, high T×A2, histamine, OVA-IgG1, OVA-IgE and OVA-IgA levels, and intense granulocyte infiltration." | 3.79 | Antigen-induced airway hyperresponsiveness in absence of broncho-obstruction in sensitized guinea pigs. ( Bazán-Perkins, B; Campos, MG; García-Zepeda, E; Martínez-Cordero, E; Ramos-Ramírez, P, 2013) |
| "Paw edema was induced with DvL in control animals, and in animals pretreated with glucocorticoid or with blockers of histamine, nitric oxide synthase, cyclooxygenase, platelet activating factor (PAF), bradykinin and lipoxygenase." | 3.79 | Neutrophil-infiltrated paw edema induced by mannose-binding Dioclea violacea lectin. ( Assreuy, AM; Cavada, BS; de Alencar, NM; do Nascimento, KS; Martins, JL; Mota, MR; Rodrigues, NV, 2013) |
| " Moreover, similar to wild-type littermates, Nf1± mice developed inflammation-induced heat and mechanical hypersensitivity, capsaicin-induced nocifensive behavior, histamine-dependent or -independent scratching, and chronic constriction injury-induced cold allodynia." | 3.79 | Assessment of pain and itch behavior in a mouse model of neurofibromatosis type 1. ( Brenner, DS; Gereau, RW; Gutmann, DH; O'Brien, DE, 2013) |
| "To determine whether histamine cells are altered in human narcolepsy with cataplexy and in animal models of this disease." | 3.79 | Greatly increased numbers of histamine cells in human narcolepsy with cataplexy. ( Cornford, M; John, J; McGregor, R; Nishino, S; Ohtsu, H; Ramanathan, L; Sakai, N; Siegel, JM; Stone, C; Thannickal, TC; Yamanaka, A, 2013) |
| "We counted the number of hypothalamic neurons producing orexin, melanin-concentrating hormone, and histamine in 7 narcolepsy patients and 12 control subjects using stereological techniques." | 3.79 | Increase of histaminergic tuberomammillary neurons in narcolepsy. ( Baumann, CR; Gavrilov, YV; Haybaeck, J; Mignot, E; Reddy, H; Scammell, TE; Valko, PO; Yamamoto, M, 2013) |
| "Curcumin, a phytochemical present in turmeric, rhizome of Curcuma longa, has been shown to have a wide variety of pharmacological activities including anti-inflammatory, anti-allergic and anti-asthmatic properties." | 3.79 | Intranasal curcumin and its evaluation in murine model of asthma. ( Chauhan, PS; Chawla, R; Dash, D; Kumar, JP; Kumari, S; Singh, M; Singh, R, 2013) |
| "Here, we sought to define the necessity for histamine receptors in the pathology of anaphylaxis using H1R and H2R knockout (KO) mice, as well as a H1R/H2R double KO strain." | 3.79 | Anaphylactic responses to histamine in mice utilize both histamine receptors 1 and 2. ( Bryce, PJ; Byrne, AJ; Chien, KB; Schroeder, HA; Wechsler, JB, 2013) |
| "Significant decrease in sneezing frequency, histamine, interleukin (IL)-4 and IL-17A and increase in TGF-β and IL-10 concentration were exhibited by the MNB-treated mice." | 3.79 | Therapeutic effects of β1, 4 mannobiose in a Balb/c mouse model of intranasally-induced pollen allergy. ( Ibuki, M; Kanatani, H; Mine, Y; Nakamura, A; Rupa, P; Yang, C, 2013) |
| " Then the rabbit atherosclerotic plaque rupture and thrombosis were triggered by injection of viper venom and histamine." | 3.79 | Pravastatin inhibits plaque rupture and subsequent thrombus formation in atherosclerotic rabbits with hyperlipidemia. ( Huang, C; Huang, Z; Jiang, H; Wu, G; Xie, Q; Xu, L, 2013) |
| "Itching guinea pig model caused by histamine, itching mice model, eczema guinea pig model caused by OVA, and inhibitory effect on pathogens in vitro were used to observe the itching threshold, symptoms and other related physiological index, as well as the inhibitory effect on the normal skin fungi by water extraction of Kochiae Fructus to evaluate the external therapeutic function of Kochiae Fructus." | 3.78 | [Normative research on bacteriostasis and relieving itching external therapeutic function of kochiae fructus]. ( Chen, SJ; Chi, HY; Liu, QY; Pin, G; Shao, LJ; She, YY; Song, LY; Wang, JN; Yao, CH, 2012) |
| " Nevertheless, the anti-inflammatory activity was tested in carrageenan induced paw edema and histamine induced inflammatory tests." | 3.78 | Antipyretic, analgesic and anti-inflammatory activity of Viola betonicifolia whole plant. ( Khan, H; Muhammad, N; Saeed, M, 2012) |
| "Wuling mycelia can delay the kindling and ameliorate the ability of learning in rats with pentylenetetrazole-induced epilepsy and the enhancement of neuronal histamine activity may be one of possible mechanisms." | 3.78 | [Effects of Wuling mycelia on pentylenetetrazole-induced epilepsy in rats]. ( Chen, GF; Hu, XY; Ren, GL; Zhang, LS, 2012) |
| "The anti-allergic effect of total bakkenolides from the rhizome of Petasites tricholobus (BAPT) was evaluated in an ovalbumin-induced allergic rhinitis model in male Wistar rats." | 3.77 | Anti-allergic effects of total bakkenolides from Petasites tricholobus in ovalbumin-sensitized rats. ( Guo, ML; Wang, Q; Wang, Y; Zhang, FJ, 2011) |
| "In the present study, the efficacy of β-sitosterol isolated from an n-butanol extract of the seeds of the plant Moringa oleifera (Moringaceae) was examined against ovalbumin-induced airway inflammation in guinea pigs." | 3.77 | Suppression of ovalbumin-induced Th2-driven airway inflammation by β-sitosterol in a guinea pig model of asthma. ( Mahajan, SG; Mehta, AA, 2011) |
| "Histamine and histamine receptors are found in atherosclerotic lesions, and their signaling and subsequent proatherogenic or proinflammatory gene expression are involved in atherogenesis." | 3.77 | Histamine deficiency decreases atherosclerosis and inflammatory response in apolipoprotein E knockout mice independently of serum cholesterol level. ( Ding, Y; Guo, X; Hirano, K; Kato, S; Kohno, K; Murata, Y; Ohtsu, H; Sasaguri, Y; Shimajiri, S; Tanimoto, A; Tsutsui, M; Wang, KY; Watanabe, T; Yamada, S, 2011) |
| "We conclude that 129S5 mice have increased susceptibility to anaphylaxis as compared to BALB/c strain and their increased susceptibility was associated with altered mast cell proliferation and homeostatic tissue levels and responsiveness to histamine." | 3.77 | Increased susceptibility of 129SvEvBrd mice to IgE-Mast cell mediated anaphylaxis. ( Ahrens, R; Arumugam, M; Finkelman, FD; Hogan, SP; Kottyan, LC; Maclennan, JA; Osterfeld, H; Shang, X; Zheng, Y; Zimmermann, N, 2011) |
| "The present study explored the interaction between histaminergic and opioidergic systems at the level of the hippocampus in modulation of orofacial pain by intra-hippocampal microinjections of histamine, pyrilamine (an antagonist of histamine H(1) receptors), ranitidine (an antagonist of histamine H(2) receptors), morphine (an opioid receptor agonist) and naloxone (an opioid receptor antagonist) in separate and combined treatments." | 3.77 | Interaction between histamine and morphine at the level of the hippocampus in the formalin-induced orofacial pain in rats. ( Erfanparast, A; Farshid, AA; Khalilzadeh, E; Tamaddonfard, E, 2011) |
| " The aim of this study was to evaluate the effects of TQ on ovalbumin (OVA)-induced allergic conjunctivitis (AC) in Balb/c." | 3.77 | Ameliorative effect of thymoquinone on ovalbumin-induced allergic conjunctivitis in Balb/c mice. ( Asim, MB; Hayat, K; Li, M; Nawaz, M; Sun, N; Zhang, L, 2011) |
| "Experimental asthma model was established in Balb/c mice sensitized by ovalbumin (OVA), followed by aerosol allergen challenges." | 3.77 | Cortex Mori Radicis extract exerts antiasthmatic effects via enhancement of CD4(+)CD25(+)Foxp3(+) regulatory T cells and inhibition of Th2 cytokines in a mouse asthma model. ( Jeong, SJ; Kim, HJ; Kim, SH; Lee, HJ; Park, EJ, 2011) |
| "The aim of this study was to evaluate the therapeutic efficacy of tolvaptan, a vasopressin V(2) receptor antagonist, on edema in two rat models: 1) histamine-induced vascular hyperpermeability of the dorsal skin and 2) carrageenan-induced paw edema." | 3.77 | Anti-edematous effects of tolvaptan in experimental rodent models. ( Fujiki, H; Miyazaki, T; Ohmoto, K; Sakamoto, Y; Yamashita, T, 2011) |
| "The present study demonstrates that gastric hypersecretion induced by histamine in combination with gastric mucosal ischemia results in gastric lesions which progress into chronic gastric ulcers." | 3.76 | Acute gastric lesions induced by the administration of histamine to rats with partial vascular occlusion: evidence for the gastroprotective effect of prostaglandin. ( Brzozowski, T; Konturek, PC; Konturek, SJ; Neurath, MF; Raithel, M; Sliwowski, Z, 2010) |
| "To elucidate the ocular pharmacological properties of bepotastine besilate, a selective histamine H(1) receptor antagonist, when compared with other histamine H(1) receptor antagonists, using guinea pig allergic conjunctivitis models and in vitro models of eosinophil recruitment and mast cell membrane stabilization." | 3.76 | Bepotastine besilate, a highly selective histamine H(1) receptor antagonist, suppresses vascular hyperpermeability and eosinophil recruitment in in vitro and in vivo experimental allergic conjunctivitis models. ( Atsumi, I; Fujii, A; Iemura, M; Kida, T; Sakai, O; Sakaki, H; Wada, T, 2010) |
| " In the present study, the effect of repeated administration of histamine on amnesia induced by post-training administration of the drug was examined." | 3.76 | Repeated histamine pretreatment decreased amnesia induced by post-training administration of the drug in a step-down inhibitory avoidance test in mice. ( Ahmadi, S; Malekmohammadi, N; Zarrindast, MR, 2010) |
| "Both manual acupuncture and histamine injection of ST 36 can relieve pain in AIA rats, which may be closely related to its effect in activating mast cells in acupoint area." | 3.76 | [Acupoint-injection of histamine induced analgesic effect in acute adjuvant-induced-arthritis rats]. ( Ding, GH; Huang, M; Xie, YY, 2010) |
| "Histamine has a positive inotropic effect on ventricular myocardium and stimulation of histamine H₂ receptors increases the intracellular cAMP level via Gs protein, as dose stimulation of β-adrenergic receptors, and worsens heart failure." | 3.76 | A histamine H₂ receptor blocker ameliorates development of heart failure in dogs independently of β-adrenergic receptor blockade. ( Asakura, M; Asanuma, H; Fujita, M; Kim, J; Kitakaze, M; Komamura, K; Minamino, T; Sanada, S; Sasaki, H; Sugimachi, M; Takahama, H; Takashima, S; Wakeno, M, 2010) |
| " On the final day of the TCE exposure period, we measured the active cutaneous anaphylaxis (ACA) reaction and the antigen- specific IgE level in serum as well as the histamine level at the allergic reaction site and assayed the proliferation rates of splenocytes collected from the animals." | 3.76 | Enhancement of immediate allergic reactions by trichloroethylene ingestion via drinking water in mice. ( Ikemoto, T; Inagaki, N; Kobayashi, R; Nagai, H; Nagase, H; Satoh, M; Seo, M, 2010) |
| "3% w/v (weight of solute per volume of solution) monoethanolamine (MEA) into his lungs, causing asthma-like symptoms." | 3.75 | Effects of inhaled monoethanolamine on bronchoconstriction. ( Hayashi, I; Ide, A; Kamijo, Y; Majima, M; Soma, K; Yoshimura, K, 2009) |
| "This study aimed to investigate the effect of piperine on airway hyperresponsiveness, pulmonary eosinophilic infiltration, various immune cell phenotypes, Th2 cytokine production, immunoglobulin E and histamine production in a murine model of asthma." | 3.75 | Piperine inhibits eosinophil infiltration and airway hyperresponsiveness by suppressing T cell activity and Th2 cytokine production in the ovalbumin-induced asthma model. ( Kim, SH; Lee, YC, 2009) |
| "Combination therapy blocking both PAF and histamine markedly reduces the severity of peanut-induced anaphylaxis, and thus it may be a potential life-saving therapeutic approach in peanut and, likely, other food-induced anaphylaxis." | 3.75 | Concurrent blockade of platelet-activating factor and histamine prevents life-threatening peanut-induced anaphylactic reactions. ( Arias, K; Baig, M; Chu, D; Colangelo, M; Coyle, A; Goncharova, S; Jordana, M; Vadas, P; Walker, T; Waserman, S, 2009) |
| "Effects of quercetin inhalation on immediate (IAR), late-phase (LAR) and late late-phase (LLAR) asthmatic responses by exposure to aerosolized-ovalbumin (AOA) (2w/v% in saline, inhalation for 3 min) were studied in conscious guinea-pigs sensitized with AOA." | 3.74 | Quercetin inhalation inhibits the asthmatic responses by exposure to aerosolized-ovalbumin in conscious guinea-pigs. ( Choi, HH; Kim, CJ; Lee, JY; Moon, H; Moon, HJ; Sim, SS, 2008) |
| " flavicarpa Degener (Passifloraceae) in the mouse model of pleurisy induced by carrageenan (Cg), bradykinin, histamine or substance P, observing the effects upon leucocytes migration, myeloperoxidase (MPO), nitric oxide (NO) concentrations and tumor necrosis factor-alpha (TNFalpha) and interleukin-1 beta (IL-1beta) levels." | 3.74 | Evidence of anti-inflammatory effects of Passiflora edulis in an inflammation model. ( Fröde, TS; Montanher, AB; Schenkel, EP; Zucolotto, SM, 2007) |
| "The contribution of the novel histamine H(4) receptor to histaminergic and allergic pruritus was investigated." | 3.74 | Histamine H4 receptor antagonists are superior to traditional antihistamines in the attenuation of experimental pruritus. ( Desai, PJ; Dunford, PJ; Karlsson, L; McQueen, D; Thurmond, RL; Williams, KN, 2007) |
| " The rhizomes aqueous extract and its two derived fractions reduced leukocytes and mononuclears in the pleurisy induced by bradykinin, histamine, or substance P (P<0." | 3.74 | Anti-inflammatory evaluation of Solidago chilensis Meyen in a murine model of pleurisy. ( Fröde, TS; Goulart, S; Lang, KL; Liz, R; Moritz, MI; Schenkel, EP, 2007) |
| " We have studied the effect of (+)-catechin on a gastric ulcer model involving damage to gastric injury by ischaemia- reperfusion (I/R) in rats." | 3.74 | Protective effect of (+)-catechin against gastric mucosal injury induced by ischaemia-reperfusion in rats. ( Rao, ChV; Vijayakumar, M, 2007) |
| " Localized inflammation was induced via injection of inflammatory agents lambda-carrageenan (CA) or histamine into rat hindpaws, alone or in conjunction with pharmacological agents, resulting in a spatially and temporally defined inflammatory reaction." | 3.74 | Acute exposure to a moderate strength static magnetic field reduces edema formation in rats. ( Morris, CE; Skalak, TC, 2008) |
| " indica dry extract (100, 200 and 400 mg kg-1) exhibited dose dependent and significant anti-inflammatory activity in acute (carrageenean and histamine induced hind paw oedema, p < 0." | 3.74 | Anti-inflammatory and anti-nociceptive activities of Fumaria indica whole plant extract in experimental animals. ( Gupta, PK; Rao, CV; Verma, AR; Vijayakumar, M, 2007) |
| "The study was dedicated to the role of serotonin in the development of experimental gastric ulcer in rats, and the role of serotonin, histamine, and purine bases in patients with peptic ulcer." | 3.74 | [The pathogenetic role of the serotonin-histamine-cyclic nucleotide system in ulcerogenesis]. ( Lazebnik, LB; Lychkova, AE; Sokolova, GN; Trubitsyna, IE, 2008) |
| "Adenosine, an important signaling molecule in asthma, produces bronchoconstriction in asthmatics." | 3.73 | A novel A1 adenosine receptor antagonist, L-97-1 [3-[2-(4-aminophenyl)-ethyl]-8-benzyl-7-{2-ethyl-(2-hydroxy-ethyl)-amino]-ethyl}-1-propyl-3,7-dihydro-purine-2,6-dione], reduces allergic responses to house dust mite in an allergic rabbit model of asthma. ( Batra, VK; Borron, P; Mustafa, SJ; Nadeem, A; Obiefuna, PC; Wilson, CN, 2005) |
| "The aims of our study were to assess whether the increased oxidative stress in experimental otitis media with effusion (OME) induced by histamine was reflected erythrocytes and middle ear effusion fluid by lipid peroxidation; to survey the alterations in antioxidant enzyme activities in experimental OME; and to determine the effect of dantrolene on this oxidative stress." | 3.73 | Effect of dantrolene on lipid peroxidation, lutathione and glutathione-dependent enzyme activities in experimental otitis media with effusion in guinea pigs. ( Aktan, B; Buyukokuroglu, ME; Elmastas, M; Taysi, S; Ucuncu, H, 2005) |
| "Sneezing and nasal scratching after challenges were significantly ameliorated in the Shu-Bi-Lin-treated group compared with the ovalbumin-sensitized and untreated group, but rhinorrhea volume was not reduced." | 3.73 | Effect of a Chinese herbal formula, Shi-Bi-Lin, on an experimental model of allergic rhinitis. ( Chen, GG; Leung, PC; van Hasselt, CA; Wang, LH; Wong, YO; Woo, JK; Zhao, Y, 2006) |
| "Pleurisy was induced by carrageenan (Cg, 1%), bradykinin (BK, 10 nmol), histamine (HIS, 1 micromol) or substance P (PS, 20 nmol) administered by intrapleural route (ipl." | 3.73 | Antiinflammatory effects of Tacrolimus in a mouse model of pleurisy. ( Fröde, TS; Medeiros, YS; Pereira, R, 2006) |
| "Using a murine model of active systemic anaphylaxis to penicillin V (Pen V), mice previously sensitized to Pen V were desensitized by oral feeding of Pen V." | 3.73 | Mechanism for acute oral desensitization to antibiotics. ( Choi, IH; Choi, IW; Chung, WC; Kang, NI; Kim, YS; Lee, HK; Song, CH; Woo, HY, 2006) |
| " Previously, it is reported that a high dose of L-97-1, a water-soluble, small molecule adenosine A(1) receptor antagonist, blocks early and late allergic responses, and bronchial hyper-responsiveness to histamine in a hyper-responsive rabbit model of allergic asthma." | 3.73 | Adenosine A1 receptor antagonist versus montelukast on airway reactivity and inflammation. ( Mustafa, SJ; Nadeem, A; Obiefuna, PC; Wilson, CN, 2006) |
| "Role in pain sensation of both nociceptin (NC), the bioactive heptadecapeptide sequence of preproorphaninFQ and of histamine has been widely evidenced in the central nervous system (CNS)." | 3.73 | [Effect of nociceptin on histamine and serotonin release in the central nervous system]. ( Gyenge, M; Hantos, M; Laufer, R; Tekes, K, 2006) |
| "In our model of asthma, guinea pigs were made sensitive with ovalbumine (OVA), a protein extracted from the white of egg, and provoked in a way repeated with aerosol challenge of OVA for the group OVA (1 challenge a day during six days)." | 3.73 | [Study of cellularity in bronchoalveolar fluid and bronchial reactivity to histamine in a model of asthma in guinea pig]. ( Aubier, M; Boczkowski, J; Lanone, S; Ouksel, H; Pretrolani, M; Samb, A, 2006) |
| "Histamine has a variety of airway actions and is considered to be an important mediator in asthma." | 3.72 | Disruption of L-histidine decarboxylase reduces airway eosinophilia but not hyperresponsiveness. ( Hattori, T; Ichinose, M; Ishigaki-Suzuki, S; Koarai, A; Kuramasu, A; Makabe-Kobayashi, Y; Ohtsu, H; Sakurai, E; Shirato, K; Sugiura, H; Watanabe, T; Yamagata, S, 2003) |
| "The present work was done to investigate the possible effects of thymoquinone on acetic acid-induced colitis in rats." | 3.72 | Thymoquinone protects against experimental colitis in rats. ( Mahgoub, AA, 2003) |
| " We investigated the role of TNF in allergic peritonitis induced by ovalbumin (OVA) challenge in double TNF (TNF-alpha(-/-)/lymphotoxin-alpha(-/-)) knock out (TNF-KO) mice." | 3.72 | Tumor necrosis factors in a murine model of allergic peritonitis: effects on eosinophil accumulation and inflammatory mediators' release. ( Levi-Schaffer, F; Pickholtz, D; Temkin, V, 2003) |
| " This research first proposed that alterations of mast cell histamine release, gastric acid back-diffusion and mucosal microvascular permeability are important in modulating gastric ulcer and hemorrhage in Salmonella typhi-infected rats." | 3.72 | Role of histamine and acid back-diffusion in modulation of gastric microvascular permeability and hemorrhagic ulcers in Salmonella typhimurium-infected rats. ( Hung, CR; Wang, PS, 2004) |
| "The study was undertaken to examine the involvement of the renin-angiotensin system in the reversal by endogenous central histamine of critical haemorrhagic hypotension in anaesthetised Wistar rats." | 3.72 | Involvement of the renin-angiotensin system in endogenous central histamine-induced reversal of critical haemorrhagic hypotension in rats. ( Jochem, J, 2004) |
| "An increase in endogenous central histamine concentrations, after loading with histamine precursor L-histidine or inhibition of histamine N-methyltransferase (HNMT) activity, produces the reversal of critical hypotension with improvement in survival of haemorrhage-shocked rats." | 3.72 | Involvement of proopiomenalocortin-derived peptides in endogenous central histamine-induced reversal of critical haemorrhagic hypotension in rats. ( Jochem, J, 2004) |
| "The aims of this study were: (a) to assess whether the increased oxidative stress in otitis media with effusion (OME) induced in guinea pigs by histamine injection into the middle ear cavity is reflected by lipid peroxidation in erythrocytes, plasma, and middle ear effusion fluid; (b) to survey the alterations of oxidant and antioxidant enzyme activities in experimental OME; and (c) to determine the effects of melatonin and methylprednisolone on this oxidative stress." | 3.72 | Protective effect of melatonin on experimental otitis media with effusion in guinea pigs. ( Aktan, B; Akyuz, M; Altas, E; Buyukokuroglu, ME; Ozabacigil, F; Ucuncu, H, 2004) |
| "5, 5 and 10 mg kg (-1)) was investigated and compared with diclofenac sodium (5 mg kg (-1)) using the formalin-, histamine-, and carrageenan-induced paw oedema and cotton pellet granuloma tests." | 3.71 | Anti-inflammatory and antinociceptive properties of dantrolene sodium in rats and mice. ( Büyükokuroğlu, ME, 2002) |
| "We prepared a model of experimental peritonitis by introducing Escherichia coli into the peritoneal cavity of the histamine-deficient mice generated by a disruption of the gene for histidine decarboxylase (HDC), the unique histamine-synthesizing enzyme." | 3.71 | Accelerated clearance of Escherichia coli in experimental peritonitis of histamine-deficient mice. ( Doi, H; Hori, Y; Kuramasu, A; Kurokawa, Y; Makabe-Kobayashi, Y; Nagy, A; Nihei, Y; Ohtsu, H; Sakurai, E; Satomi, S; Terui, T; Watanabe, T, 2002) |
| "To clarify the contribution of stress to classical conditioning-associated asthmatic responses, the effect of fasting stress on conditioned histamine release was investigated in a guinea pig model of asthma." | 3.71 | Fasting stress exacerbates classical conditioned histamine release in guinea pigs. ( Endo, Y; Irie, M; Nagata, S, 2002) |
| " Brown Norway (BN) rats were sensitized by daily OVA (ovalbumin)-gavage or by drinking OVA containing water ad libitum and the ASA (active systemic anaphylaxis) response, as the immediate hypersensitivity response to antigen stimulation after oral sensitization, was examined." | 3.71 | Examination of oral sensitization with ovalbumin in Brown Norway rats and three strains of mice. ( Akiyama, H; Goda, Y; Okunuki, H; Sakushima, JI; Sawada, JI; Teshima, R; Toyoda, M, 2001) |
| " coli-induced acute infectious peritonitis in rats previously depleted on mast cells of peritoneal cavity the replacing effects of various doses of exogenous histamine, serotonin and heparin and their complex on leukocytic reaction of inflammatory focus and blood were studied." | 3.71 | [Modulating effects of exogenous histamine, serotonin, and heparin on leukocytic reaction during inflammation]. ( Klymenko, MO; Pyshnov, HIu, 2001) |
| "We studied the antiischemic properties of fasudil, a Rho-kinase inhibitor, in conscious rabbits with coronary vasospasm induced by vasopressin and endothelin." | 3.71 | Antiischemic properties of fasudil in experimental models of vasospastic angina. ( Asano, T; Ikegaki, I; Sato, S; Shimokawa, H, 2001) |
| "The ovalbumin (OVA)-sensitized guinea pig is often used as an animal model of asthma and airway hyperreactivity." | 3.71 | Enhanced expression of mucin genes in a guinea pig model of allergic asthma. ( Adler, KB; Chorley, B; Fine, J; Greenfeder, S; Li, Y; Martin, LD; Minnicozzi, M; Pettersen, CA, 2001) |
| " The acute gastric ulcer models used were pylorus ligation, indomethacin, ethanol and histamine induced acute gastric ulcers." | 3.71 | Gastric antisecretory and antiulcer activity of oxytocin in rats and guinea pigs. ( Abraham, BK; Asad, M; Koumaravelou, K; Ramaswamy, S; Shewade, DG; Vasu, S, 2001) |
| " Experimental cystitis was induced in female mice by intravesical instillation of SP, LPS, or fluorescein-labeled LPS." | 3.71 | LPS-sensory peptide communication in experimental cystitis. ( Bjorling, DE; Haak-Frendscho, M; Hammond, TG; Saban, MR; Saban, R; Steinberg, H; Tengowski, MW, 2002) |
| "Rats with portocaval anastomosis (PCA), an animal model of hepatic encephalopathy (HE), have very high brain histamine concentrations." | 3.71 | Neuronal storage of histamine in the brain and tele-methylimidazoleacetic acid excretion in portocaval shunted rats. ( Andrzejewski, W; Fogel, WA; Granerus, G; Maslinski, C; Michelsen, KA; Panula, P; Sasiak, K, 2002) |
| "To show a relationship between intranasal histamine challenge, the development of middle ear effusion and Eustachian tube (ET) dysfunction in a rat model." | 3.71 | Effect of intranasal histamine challenge on Eustachian tube function. ( Dubin, MG; Ebert, CS; McQueen, CT; Pillsbury, HC; Pollock, HW; Prazma, J; Scharer, SS, 2002) |
| "In the air pouch-type allergic inflammation in rats, we reported that a sustained histamine production in the late phase is induced by a cytokine-like factor, named histamine-production-increasing factor (HPIF) (1)." | 3.70 | Increase in histamine production by inflammatory exudate in the chronic phase of allergic inflammation in rats. ( Hirasawa, N; Mue, S; Ohuchi, K; Oikawa, S; Shiraishi, M, 1998) |
| "This study describes the anti-inflammatory actions of NPC 18884, a non-peptide bradykinin B2 receptor antagonist in bradykinin and carrageenan-induced inflammation in the mouse model of pleurisy." | 3.70 | Oral anti-inflammatory action of NPC 18884, a novel bradykinin B2 receptor antagonist. ( Calixto, JB; Chakravarty, S; Creczynski-Pasa, TB; Kyle, DJ; Mavunkel, BJ; Saleh, TS; Vianna, RM, 1998) |
| " Intragastric challenge with CM at week 6 elicited systemic anaphylaxis accompanied by vascular leakage, significantly increased plasma histamine, and increased intestinal permeability to casein." | 3.70 | A murine model of IgE-mediated cow's milk hypersensitivity. ( Huang, CK; Kleiner, GI; Li, XM; Sampson, HA; Schofield, BH, 1999) |
| " When the eyes were treated with histamine, a complement C5a analogue peptide and hydrogen peroxide, typical signs of uveitis were produced." | 3.70 | Arterially perfused eye model of uveitis. ( Sanderson, SD; Shiels, IA; Taylor, SM, 1999) |
| " Compared with non-immunized mice or mice treated with 'naked' DNA, mice immunized with nanoparticles showed a substantial reduction in allergen-induced anaphylaxis associated with reduced levels of IgE, plasma histamine and vascular leakage." | 3.70 | Oral gene delivery with chitosan--DNA nanoparticles generates immunologic protection in a murine model of peanut allergy. ( Huang, SK; Leong, KW; Mao, HQ; Roy, K, 1999) |
| "Bleomycin was subcutaneously injected every day in WBB6F1-W/W(V) and their normal littermate WBB6F1-+/+ mice for 4 weeks, and mice were analyzed for histological sclerosis, mast cell number, plasma histamine level, and hydroxyproline content." | 3.70 | Animal model of sclerotic skin. II. Bleomycin induced scleroderma in genetically mast cell deficient WBB6F1-W/W(V) mice. ( Katayama, I; Nishioka, K; Takagawa, S; Takahashi, Y; Yamamoto, T, 1999) |
| " Granulated bladder mast cells per mm2 of bladder tissue and urine histamine content were monitored as the cystitis developed over the next few days." | 3.70 | CNS induced neurogenic cystitis is associated with bladder mast cell degranulation in the rat. ( Janni, G; Jasmin, L; Ohara, PT; Rabkin, SD, 2000) |
| "0 mg ovalbumin (OVA) by gavage every day for 9 weeks, and active systemic anaphylaxis (ASA) was induced by intraperitoneal injection of OVA." | 3.70 | Induction of active systemic anaphylaxis by oral sensitization with ovalbumin in mast-cell-deficient mice. ( Akiyama, H; Goda, Y; Okunuki, H; Sakushima, J; Sawada, JI; Teshima, R; Toyoda, M, 2000) |
| "Three experiments were conducted to examine the role of histamine in neuronal degeneration in a rat model of Wernicke's encephalopathy induced by an acute bout of pyrithiamine-induced thiamine deficiency (PTD)." | 3.69 | Histamine-mediated neuronal death in a rat model of Wernicke's encephalopathy. ( Barke, KE; Hough, LB; Langlais, PJ; Weilersbacher, G; Zhang, SX, 1994) |
| "Acetylshikonin, a naphthoquinone isolated from the Chinese herb medicine, tzu ts'ao, was demonstrated to inhibit the polymyxin B-induced hind-paw edema in normal as well as in adrenalectomized mice." | 3.69 | Inhibition of hind-paw edema and cutaneous vascular plasma extravasation in mice by acetylshikonin. ( Chang, LC; Kuo, SC; Raung, SL; Wang, JP, 1995) |
| "We have investigated the effects of actinomycin D on mouse ear oedema induced by capsaicin, neuropeptides, and established inflammatory mediators." | 3.69 | Inhibition by actinomycin D of neurogenic mouse ear oedema. ( Inoue, H; Koshihara, Y; Nagata, N, 1995) |
| "We have determined the inhibitory activity of dexamethasone as an inhibitor of histamine-induced plasma protein extravasation (PPE) in guinea-pig lung and skin, and of lipopolysaccharide (LPS)-induced neutrophilia and platelet activating factor (PAF)-induced eosinophilia in guinea-pig lungs." | 3.69 | Inhibition of some aspects of acute inflammation of guinea-pig lung by intraperitoneal dexamethasone and mifepristone: demonstration of agonist activity of mifepristone in the guinea-pig. ( Hughes, SC; Whelan, CJ; Wren, GP, 1995) |
| "Although diphenhydramine hydrochloride is known to eliminate or reduce the symptoms of dystonia in human patients with acute dystonic reactions and idiopathic torsion dystonia, its mechanism of action is still unclear." | 3.69 | Evidence for the involvement of histamine in the antidystonic effects of diphenhydramine. ( Matsumoto, RR; Stone, MR; Truong, DD; van't Groenewout, JL; Vo, VN, 1995) |
| "A new guinea pig model of allergic asthma was used to investigate the effects of low doses of the phosphodiesterase inhibitors, rolipram (phosphodiesterase IV selective), ORG 20241 (N-hydroxy-4-(3,4-dimethoxyphenyl)-thiazole-2-carboximidamide; dual phosphodiesterase III/IV inhibitor with some selectivity for the phosphodiesterase IV isoenzyme), and of theophylline (non-selective) on allergen-induced early and late phase asthmatic reactions, bronchial hyperreactivity to histamine inhalation, and airway inflammation." | 3.69 | Phosphodiesterase inhibitors reduce bronchial hyperreactivity and airway inflammation in unrestrained guinea pigs. ( Meurs, H; Olymulder, CG; Santing, RE; Van der Molen, K; Zaagsma, J, 1995) |
| "Daily oral administration of cimetidine or omeprazole markedly accelerated the healing of acetic acid-induced gastric ulcers in rats with a limited food intake time." | 3.69 | Cimetidine and omeprazole accelerate gastric ulcer healing by an increase in gastrin secretion. ( Inaguma, K; Ito, M; Segami, T; Suzuki, Y, 1994) |
| "To elucidate the mechanism of development of asthma, we tried to develop a model which elicited a late asthmatic response by a combination of systemic and inhaled sensitization with ovalbumin in guinea pigs." | 3.69 | Relationship between airway eosinophilia and airway hyperresponsiveness in a late asthmatic model of guinea pigs. ( Itoh, K; Mukaiyama, O; Satoh, Y; Takahashi, E; Yamaguchi, T, 1996) |
| "The effects of the histamine precursor, L-histidine, were examined in the rat kindling model of epilepsy." | 3.69 | Biphasic action of the histamine precursor L-histidine in the rat kindling model of epilepsy. ( Koshino, Y; Nakamura, M; Shiraishi, J; Wada, Y, 1996) |
| "On the model of carrageenen-induced acute aseptic peritonitis in rats the regularities of the functional state of mast cells (MC), of the content of free and cellular histamine in exudate and mesenterium and histamine in blood from the 5th minute up to 10th day after injection of phlogogene have been studied." | 3.69 | [Mast cells in a focus of carrageenan-induced acute aseptic inflammation]. ( Klymenko, MO; Pavlova, OO, 1997) |
| "The role of substance P in experimental allergic conjunctivitis induced by egg albumin was investigated with guinea pigs." | 3.69 | Role of substance P in experimental allergic conjunctivitis in guinea pigs. ( Fujiwara, R; Izushi, K; Kamei, C; Ohishi, H; Sugimoto, Y; Takada, M; Yamaji, M, 1997) |
| "The role of indomethacin-induced peptic ulceration in gastric acid secretion was investigated using albino rats of Wistar strain in early, mid and late pregnancy." | 3.68 | Role of indomethacin-induced peptic ulceration in gastric acid secretion in pregnant rats. ( Bolarinwa, Y; Evbuomwan, MI, 1993) |
| "The bisbenzylisoquinoline analogues, tetrandrine and berbamine, were investigated for their effects on guineapig airway microvascular leakage, an animal model of asthma and allergic inflammation." | 3.68 | Comparative effects of tetrandrine and berbamine on guineapig airway microvascular leakage induced by platelet-activating factor and other allergic mediators. ( Seow, WK; Thong, YH; Wong, CW, 1993) |
| "The effect of neutropenia on acute and chronic inflammatory oedema in rats was assessed using histamine, carrageenan and Freund's complete adjuvant as inducers." | 3.68 | The role of neutrophils in acute and chronic inflammation in rats. ( Ezeamuzie, IC; Njoku, AC, 1992) |
| "Recent studies have demonstrated a connection between xanthine oxidase-generated reactive oxygen intermediates and histamine release during ischemia-reperfusion." | 3.68 | Studies on the relationship between xanthine oxidase and histamine release during intestinal ischemia-reperfusion. ( Bakó, L; Boros, M; Kaszaki, J; Nagy, S, 1992) |
| "The role of histamine in neutrophil infiltration and vascular permeability response in carrageenin air pouch inflammation in rats was examined." | 3.68 | Downward regulation of neutrophil infiltration by endogenous histamine without affecting vascular permeability responses in air-pouch-type carrageenin inflammation in rats. ( Hirasawa, N; Mue, S; Ohuchi, K; Tsurufuji, S; Watanabe, M, 1991) |
| "We studied the effects of coenzyme Q10 (CoQ10) on pulmonary function and chemical mediators in a canine model of hemorrhagic shock." | 3.68 | Effects of coenzyme Q10 in hemorrhagic shock. ( Yamada, M, 1990) |
| "The present study was made on an experimental animal model of a death from anaphylaxis, in which postmortem changes in levels of histamine and 1-methylhistamine, in whole blood were measured." | 3.68 | An experimental model of death from anaphylactic shock with compound 48/80 and postmortem changes in levels of histamine in blood. ( Fukuma, Y; Hara, K; Hieda, Y; Kageura, M; Kashimura, S; Takamoto, M, 1990) |
| "Healing of duodenal ulcers induced by indomethacin + histamine was investigated in rats." | 3.67 | Healing process of duodenal ulcers induced by indomethacin plus histamine in rats. ( Niida, H; Okabe, S; Okada, M; Takeuchi, K, 1989) |
| "The role of the central histaminergic system in depression was studied by using swimming despair test in mice - a behavioural model of depression." | 3.67 | Role of central histaminergic mechanism in behavioural depression (swimming despair) in mice. ( Dhawan, KN; Gulati, A; Gupta, GP; Nath, C, 1988) |
| " To separately evaluate the ability of isoproterenol, a beta-adrenergic agonist, to prevent mediator release and anaphylactic shock, as well as to reverse the cardiopulmonary manifestations of systemic anaphylaxis, we administered a continuous infusion of isoproterenol before and during canine anaphylactic shock." | 3.67 | Prevention of canine anaphylaxis with isoproterenol. ( Bleecker, ER; Kagey-Sobotka, A; Lichtenstein, LM; Silverman, HJ; Smith, PL; Taylor, WR, 1986) |
| "The present studies were undertaken to obtain histamine (HIST) dose-response curves for tracheal smooth muscle (TSM) from an actively ragweed-sensitized canine model of asthma and to compare these results with 1) HIST dose-response data from littermate control dogs, 2) initially nonsensitized TSM passively sensitized (in vitro) to ragweed and 3) the dose-response curve to an agonist that opens primarily voltage-sensitive calcium channels, i." | 3.67 | Effect of atropine on the hyperresponsiveness of ragweed-sensitized canine tracheal smooth muscle. ( Antonissen, LA; Kepron, W; Kroeger, EA; Mitchell, RW; Stephens, NL, 1986) |
| "Praomys (Mastomys) natalensis, an African rodent ranging in size between a mouse and a rat, is more susceptible to the induction of duodenal ulcers by constant infusion of exogenous histamine through an osmotic minipump implanted subcutaneously than other rodent species tested such as mouse, rat, or guinea-pig." | 3.66 | Praomys (Mastomys) natalensis: animal model for study of histamine-induced duodenal ulcers. ( Hosoda, S; Ikedo, H; Saito, T, 1981) |
| "Insight into the pathogenesis and etiology of experimental duodenal ulceration was sought by studying the modulation of this disease in rats by selective vagotomy, chemical sympathectomy, histamine depletion, histamine H-2 receptor antagonists (eg, metiamide, cimetidine), or endocrine ablations." | 3.66 | Pathogenesis of duodenal ulceration produced by cysteamine or propionitrile: influence of vagotomy, sympathectomy, histamine depletion, H-2 receptor antagonists and hormones. ( Haith, LR; Reynolds, ES; Szabo, S, 1979) |
| "Histamine release could be shown in 50% of the dogs suffering from acute haemorrhagic pancreatitis in Pfeffer's preparation." | 3.66 | Histamine and pancreatitis: increase of plasma histamine levels in dogs with Pfeffer preparation and influence of aminoguanidine on the survival time. ( Kresse, U; Lange, E; Lorenz, W; Maroske, D; Neuhaus, H; Reimann, HJ; Schult, H; Schwarz, B, 1978) |
| "The effects of cimetidine, a new histamine H2-receptor antagonist, on the development of experimental gastric and duodenal ulcers were studied." | 3.65 | Effects of cimetidine, a histamine H2-receptor antagonist, on various experimental gastric and duodenal ulcers. ( Okabe, S; Takagi, K; Takeuchi, K; Urushidani, T, 1977) |
| "In using the technique of histamine in beeswax peptic ulceration in dogs, these experimental preparations were studied as to their efficacy to protect against ulceration: laparotomy controls; bilateral truncal vagotomy and pyloroplasty; a 50 per cent gastrectomy and vagotomy plus a Billroth II gastrojejeunostomy; a 50 per cent segmental resection of the gastric antrum and corplus plus bilateral truncal vagotomy and pyloroplasty; a 75 per cent gastrectomy and Billroth II gastrojejeunostomy, and a 75 per cent segmental resection of the gastric antrum and corpus and bilateral truncal vagotomy and pyloroplasty." | 3.65 | Segmental gastric antral resection in experimental peptic ulceration. ( Barrett, BM; German, RH; Grace, S; Hill, GS; State, D, 1977) |
| " The histamine-induced edema of the skin, the postischemic edema of muscle and the cerebral edema provoked by cold injury were used." | 3.65 | [Possible therapeutic influences on experimentally induced edemas (author's transl)]. ( Arnold, M; Przerwa, M, 1976) |
| "An oral sensitization mouse model of peanut allergy was used to assess the activity of Ara h 2/6 (20 kD) and CPE without the 20 kD fraction (CPE w/o 20 kD) for allergic provocation challenge and immunotherapy." | 2.77 | The 2S albumin allergens of Arachis hypogaea, Ara h 2 and Ara h 6, are the major elicitors of anaphylaxis and can effectively desensitize peanut-allergic mice. ( Chen, X; Dreskin, SC; Duncan, MW; Kulis, M; Lew, J; Murray, KS; Patel, OP; Porterfield, HS; W Burks, A; Wang, Q; Zhuang, Y, 2012) |
| "Histamine is a well-characterized neuromodulator that follows a circadian rhythm, regulates IOP and modulates retinal circuits and vision." | 2.72 | Novel Insight of Histamine and Its Receptor Ligands in Glaucoma and Retina Neuroprotection. ( Lanzi, C; Lucarini, L; Masini, E; Sgambellone, S, 2021) |
| "Given the nature of migraine attacks, fully reversible and treatable, the headache- or migraine-provoking property of naturally occurring signaling molecules can be tested in a human model." | 2.49 | Pearls and pitfalls in human pharmacological models of migraine: 30 years' experience. ( Ashina, M; Hansen, JM; Olesen, J, 2013) |
| "Histamine plays significant roles in early-phase swelling via H₁ receptors and in late-phase swelling via H₃/H₄ receptors in this TPA-modified allergic dermatitis model." | 2.47 | [Roles of histamine in the exacerbated allergic dermatitis]. ( Hirasawa, N; Ohuchi, K, 2011) |
| "Histamine is a ubiquitous inflammatory mediator intimately associated with the pathology of allergy." | 2.46 | The role of histamine in asthma. ( Dunford, PJ; Holgate, ST, 2010) |
| "Histamine antagonists have been in clinical use since 1942." | 2.38 | H1- and H2-antagonists in allergic and pseudoallergic diseases. ( Behrendt, H; Ring, J, 1990) |
| "Human hypersensitivity angiitis is a disease involving deposition of immune complexes in which patients present with palpable purpuric lesions most often on the lower extremities and sometimes associated with multiple organ involvement." | 2.38 | Human hypersensitivity angiitis. ( Sams, WM, 1989) |
| "Many studies show that the number of cognitive impairmentscan be reduced by antagonists of the histamine H3 receptor (H3R)." | 1.91 | Amelioration of cognition impairments in the valproic acid-induced animal model of autism by ciproxifan, a histamine H3-receptor antagonist. ( Esmaeilpour, K; Sepehri, G; Sheibani, V; Shekari, MA; Taheri, F, 2023) |
| "Atopic dermatitis is often associated with increased pain." | 1.91 | Crisaborole Inhibits Itch and Pain by Preventing Neutrophil Infiltration in a Mouse Model of Atopic Dermatitis. ( Akiyama, T; Bystrom, L; Ishida, H; Markan, A; Pavlenko, D; Todurga Seven, Z; Verpile, R, 2023) |
| "Bronchial asthma is a chronic lung disorder, that affects an estimated 262 million people worldwide, thereby, causing a large socio-economic burden." | 1.72 | Orally administered solasodine, a steroidal glycoalkaloid, suppresses ovalbumin-induced exaggerated Th2-immune response in rat model of bronchial asthma. ( Arora, P; Chellappan, DK; Dua, K; Gupta, G; Nainwal, LM; Oliver, BG; Singh, SK, 2022) |
| "Scoring of lung inflammation was performed to observe pathological changes in response to SBP treatment compared to OVA/Alum." | 1.72 | ( Han, BK; Huang, WY; Jeong, I; Kim, JK; Kim, MJ; Kim, YJ; Lee, SH; Oh, SJ; Pan, JH; Shin, EC; Yoon, H, 2022) |
| "Systemic anaphylaxis is a severe hypersensitive allergic reaction resulting from degranulation of mast cells or basophils after cross-linking of surface high-affinity IgE receptors (Fcε-RI) with allergen-specific IgE and allergens." | 1.62 | Bovine β-lactoglobulin-induced passive systemic anaphylaxis model using humanized NOG hIL-3/hGM-CSF transgenic mice. ( Ito, M; Ito, R; Katano, I; Otsuka, I; Simons, PJ; Suemizu, H; Takahashi, T, 2021) |
| "Motion sickness is a multi-system syndrome caused by abnormal spatial environmental sensory conflicts." | 1.62 | Integrated metabolomics and network pharmacology approach to exploring the potential mechanism of tianxiang capsule for treating motion sickness. ( Cao, Y; Chen, S; Chen, X; Li, F; Liu, Y; Zhang, W, 2021) |
| "Shrimp allergy, a common form of food allergy is an adverse immunological response to shrimp proteins." | 1.56 | In vivo characterization of histological and immunological response of allergic protein of Metapenaeus dobsonii using an adjuvant free BALB/c mice model. ( Panda, SK; S J, L; T V, S, 2020) |
| "Histamine was measured in serum collected 30 minutes post-OFC." | 1.56 | Peanut applied to the skin of nonhuman primates induces antigen-specific IgG but not IgE. ( Jorgensen, MJ; Kavanagh, K; Kulis, MD; Smeekens, JM, 2020) |
| "Apigenin is a natural flavone with anti-inflammatory and antioxidant properties and antitumor abilities against several types of cancers." | 1.56 | Apigenin Inhibits Histamine-Induced Cervical Cancer Tumor Growth by Regulating Estrogen Receptor Expression. ( Che, H; Cheng, L; Fan, Z; Han, S; Zhang, E; Zhang, Y, 2020) |
| "The detection of drug-induced anaphylactoid reactions remains a global challenge,still lacking mature and reliable animal models or test methods." | 1.51 | [Establishment of new evaluation standards for systemic anaphylactoid reactions using mouse model]. ( Kang, LJ; Xie, JJ; Yi, JJ; Zhang, LB; Zhao, L, 2019) |
| "Contact urticaria is recognized as the wheal and flare reaction at a site from direct contact with a chemical or protein agent." | 1.51 | Effects of RNA interference-mediated E-selectin gene silencing on cell adhesion molecule expression and cell-cell adhesion in vascular endothelial cells in mice with immunologic contact urticaria. ( Chen, YJ; Du, TP; Meng, ZD; Qin, GF; Tian, B; Wang, XL; Wang, Y; Zhao, HB, 2019) |
| "The histamine concentration was lower in the peritoneal and bone marrow-derived mast cells of bg/bg mice compared with those of bg/+ and +/+ mice, but the histamine release response was potentiated." | 1.51 | Morphological and functional analysis of beige (Chèdiak-Higashi syndrome) mouse mast cells with giant granules. ( Kiyoi, T; Liu, S; Maeyama, K; Mogi, M; Ogasawara, M; Sahid, MNA; Shudou, M, 2019) |
| "Pretreatment with berberine prevented morphological changes in IgE-stimulated RBL-2H3 cells such as the recovery of an elongated shape." | 1.51 | Berberine suppresses mast cell-mediated allergic responses via regulating FcɛRI-mediated and MAPK signaling. ( Fu, M; Fu, S; Hong, T; Ni, S; Wang, D, 2019) |
| "Histamine was provided to primary microglia and NSC-34 motor neurons expressing the SOD1-G93A mutation." | 1.51 | Histamine Is an Inducer of the Heat Shock Response in SOD1-G93A Models of ALS. ( Amadio, S; Ammassari-Teule, M; Apolloni, S; Caputi, F; Fabbrizio, P; Pignataro, A; Volonté, C, 2019) |
| "Otitis media with effusion is a clinical manifestation characterised by inflammation of middle-ear mucosa." | 1.48 | The anti-inflammatory effects of erythromycin, clarithromycin, azithromycin and roxithromycin on histamine-induced otitis media with effusion in guinea pigs. ( Aktan, B; Ersoy, B; Kilic, K; Sakat, MS; Sipal, S, 2018) |
| "Most drugs used to treat pain and inflammation have potential side effects, which makes it necessary to search for new sources of bioactive molecules." | 1.48 | LASSBio-1586, an N-acylhydrazone derivative, attenuates nociceptive behavior and the inflammatory response in mice. ( Alencar Filho, EB; Almeida, JRGDS; Barreiro, EJL; Diniz, TC; Lavor, ÉM; Lima, LM; Lima-Saraiva, SRG; Mendes, RL; Oliveira Júnior, RG; Silva, JC; Silva, MGE; Soares, JMD, 2018) |
| "This will promote the research and treatment of pruritus and depression." | 1.48 | The behavioral study on the interactive aggravation between pruritus and depression. ( Bai, Y; Feng, YP; Li, H; Wang, XD; Yang, G, 2018) |
| "Histamine plays an important role in physiology and pathophysiology of cardiovascular system." | 1.48 | Experimental autoimmune myocarditis in rats and therapeutic histamine H1 - H4 receptor inhibition. ( Fogel, WA; Gola, J; Kobos, J; Kraszewska, K; Mazurek, U; Mussur, M; Stark, H; Stasiak, A, 2018) |
| "Allergic rhinitis is a common heterogeneous chronic upper airway disorder and is an IgE-mediated inflammation characterized by one or more nasal symptoms such as sneezing, itching, nasal discharge, rhinorrhea, post nasal drainage and nasal blockage." | 1.46 | Skullcapflavone II attenuates ovalbumin-induced allergic rhinitis through the blocking of Th2 cytokine production and mast cell histamine release. ( Bui, TT; Chai, OH; Piao, CH; Song, CH, 2017) |
| "Allergy is an acquired hypersensitivity reaction of the immune system mediated by IgE‑induced mast cell degranulation." | 1.46 | Anti‑allergic action of bacillus Calmette‑Guerin extract in experimental mast cell‑mediated anaphylactic models. ( Sun, M; Wang, Y; Yao, W; Yu, X; Zhao, H, 2017) |
| "Muscle pain was induced by intramuscular injection of a diluted formalin solution (2." | 1.46 | Role of thalamic ventral posterolateral nucleus histamine H ( Ghasemi, H; Soltanalinejad, F; Tamaddonfard, E, 2017) |
| "Chronic pain affects the lives of millions yearly, but few new treatments are available." | 1.46 | A novel zebrafish-based model of nociception. ( DeBerry, JJ; Dewberry, LS; Sorge, RE; Taylor, JC; Totsch, SK; Watts, SA; Yessick, LR, 2017) |
| "Ongoing neuropathic pain and its attenuation by histamine was assessed using conditioned place-preference test." | 1.43 | Spinal histamine in attenuation of mechanical hypersensitivity in the spinal nerve ligation-induced model of experimental neuropathy. ( Pertovaara, A; Viisanen, H; Wei, H; You, HJ, 2016) |
| "The study investigated the effect of subchronic dosing (once daily, 7 days) of histamine H3 receptor (H3R) antagonists, ciproxifan (CPX) (3 mg/kg, i." | 1.43 | Histamine H3 receptor antagonists display antischizophrenic activities in rats treated with MK-801. ( Akhtar, M; Goswami, D; Jahan, K; Mahmood, D, 2016) |
| "Treatments to reverse peanut allergy remain elusive." | 1.43 | Investigation of peanut oral immunotherapy with CpG/peanut nanoparticles in a murine model of peanut allergy. ( Caplan, MJ; Fahmy, TM; Li, XM; Sampson, HA; Siefert, A; Srivastava, KD, 2016) |
| "Histamine level was higher in controls and the 4-aminopyridine group but reduced in the EPI group." | 1.43 | 4-Aminopyridine, A Blocker of Voltage-Dependent K+ Channels, Restores Blood Pressure and Improves Survival in the Wistar Rat Model of Anaphylactic Shock. ( Aburawi, EH; Al-Hammadi, S; Alper, SL; Bellou, A; Bellou, L; Bellou, S; Dhanasekaran, S; Kazzam, E; Nemmar, A; Oulhaj, A; Shafiuallah, M; Yasin, J; Zerrouki, M, 2016) |
| "Histamine is a key immunoregulatory mediator in immediate-type hypersensitivity reactions and chronic inflammatory responses, in particular histamine suppresses proinflammatory responses to bacterial ligands, through histamine receptor 2 (H2R)." | 1.43 | Histamine Receptor 2 is Required to Suppress Innate Immune Responses to Bacterial Ligands in Patients with Inflammatory Bowel Disease. ( Akdis, CA; Ferstl, R; Frei, R; Groeger, D; Jutel, M; Konieczna, P; OʼMahony, L; Perez, NR; Schiavi, E; Smolinska, S, 2016) |
| "To establish a food allergy model in Brown Norway (BN) rats by gavage of ovalbumin (OVA) without any adjuvant, and to evaluate this model." | 1.43 | [Establishment of a rat model of oral food allergy]. ( Li, F; Ma, JQ; Sheng, XY; Wang, JL; Zhu, QL, 2016) |
| "The model of acute pulmonary embolism in rabbits demonstrated reduced pulmonary blood flow, cardiac output, left atrial pressure, and blood flow in venae cavae against the background of elevated left pulmonary artery pressure and increased pulmonary vascular resistance." | 1.43 | Peculiarities of Blood Flow Changes in Venae Cavae during Experimental Pulmonary Embolism. ( Evlakhov, VI; Poyassov, IZ; Shaidakov, EV, 2016) |
| "Histamine is a mast cell mediator released e." | 1.42 | Communication between mast cells and rat submucosal neurons. ( Althaus, M; Bell, A; Diener, M, 2015) |
| "Histamine was able also to potentiate in vivo the anti-tumoral effect of radiation, increasing the exponential tumor doubling time." | 1.42 | Enhancement of ionizing radiation response by histamine in vitro and in vivo in human breast cancer. ( Balestrasse, KB; Blanco, H; Cortina, JE; Cremaschi, GA; Martinel Lamas, DJ; Medina, VA; Rivera, ES; Sterle, HA; Valli, E; Ventura, C, 2015) |
| "Histamine levels were evaluated in serum." | 1.42 | Histamine restores biliary mass following carbon tetrachloride-induced damage in a cholestatic rat model. ( Francis, H; Francis, T; Graf, A; Hargrove, L; Harris, R; Hodges, K; Johnson, C; Kennedy, L; Ueno, Y, 2015) |
| "We found that pronounced hyperlipidemia-induced atherosclerotic progression occurred in HH1R/apoE-DKO mice, but in HH2R/apoE-DKO mice less atherosclerosis, despite pro-atherogenic serum cholesterol levels compared with apoE-KO mice." | 1.42 | Novel function of histamine signaling in hyperlipidemia-induced atherosclerosis: Histamine H1 receptors protect and H2 receptors accelerate atherosclerosis. ( Sasaguri, Y; Tanimoto, A; Wang, KY; Yamada, S, 2015) |
| "Piperine (PIP) has been reported to exhibit anti-inflammatory, anti-histaminic, and immunomodulatory activities; however, its antiallergic profile has not been studied." | 1.42 | Antiallergic effect of piperine on ovalbumin-induced allergic rhinitis in mice. ( Aswar, M; Aswar, U; Chepurwar, S; Shintre, S, 2015) |
| "In a clinical scenario, oral mucositis affects patients' treatment and quality of life." | 1.42 | Histamine reduces boron neutron capture therapy-induced mucositis in an oral precancer model. ( Aromando, RF; Curotto, P; Farías, RO; Garabalino, MA; Gonzalez, SJ; Heber, EM; Itoiz, ME; Martinel Lamas, DJ; Medina, VA; Monti Hughes, A; Nigg, DW; Pozzi, E; Rivera, ES; Schwint, AE; Thorp, SI; Trivillin, VA, 2015) |
| "T1AM-induced hyperalgesia (1." | 1.42 | In the brain of mice, 3-iodothyronamine (T1AM) is converted into 3-iodothyroacetic acid (TA1) and it is included within the signaling network connecting thyroid hormone metabolites with histamine. ( Chiellini, G; De Siena, G; Landucci, E; Laurino, A; Raimondi, L; Saba, A; Zucchi, R, 2015) |
| "Food allergy can influence the development of colorectal cancer, although the underlying mechanisms are unclear." | 1.42 | IL-17 producing mast cells promote the expansion of myeloid-derived suppressor cells in a mouse allergy model of colorectal cancer. ( Chen, X; Chu, T; Churchill, MJ; Fung, MC; Jiang, Z; Mukherjee, S; Nagar, KK; Renz, BW; Rush, BS; Tailor, YH; Wang, EB; Wang, H; Wang, TC; Worthley, DL, 2015) |
| "Sporadic mast cell neoplasms and gastrointestinal stromal tumors (GISTs) often have various types of somatic gain-of-function mutations of the c-kit gene which encodes a receptor tyrosine kinase, KIT." | 1.42 | Characterization of various types of mast cells derived from model mice of familial gastrointestinal stromal tumors with KIT-Asp818Tyr mutation. ( Hashikura, Y; Hirota, S; Isozaki, K; Kajimoto, N; Liu-Kimura, NN; Nakai, N; Ohkouchi, M, 2015) |
| "Histamine levels were assayed in MC/9 cells stimulated with 50 nM PMA and 1 μM A23187." | 1.40 | Artemisia capillaris inhibits atopic dermatitis-like skin lesions in Dermatophagoides farinae-sensitized Nc/Nga mice. ( Ha, H; Lee, H; Lee, JK; Lee, MY; Lim, HS; Seo, CS; Shin, H, 2014) |
| "Azelastine has unique effects on dendritic cells and T cell interaction in vitro." | 1.40 | Unique immunomodulatory effects of azelastine on dendritic cells in vitro. ( Bäumer, W; Kietzmann, M; Schumacher, S; Stark, H, 2014) |
| "In group 2 (n = 7), cardiac tamponade was induced for 60 minutes by the administration of intrapericardial fluid, while the mean arterial pressure was kept in the interval 40 to 45 mm Hg." | 1.39 | Complement C5A antagonist treatment improves the acute circulatory and inflammatory consequences of experimental cardiac tamponade. ( Boros, M; Érces, D; Imai, M; Kaszaki, J; Nagy, E; Nógrády, M; Okada, H; Okada, N; Süveges, G; Varga, G; Vass, A, 2013) |
| "Histamine has been suggested to participate in seizure control." | 1.39 | Effect of hyperthermia on histamine blood level and convulsive behavior in infant rats. ( Fereidoni, J; Gholipoor, P; Roshan-Milani, S; Saboory, E, 2013) |
| "Kaempferol (KP) is a major compound of Naju Jjok (Polygonum tinctorium Lour." | 1.39 | Evaluation of the effect of kaempferol in a murine allergic rhinitis model. ( Han, NR; Jeong, HJ; Kim, HM; Kim, MJ; Oh, HA, 2013) |
| "Pre-treatment with quercetin for 3weeks suppressed TDI-induced nasal allergy-like symptoms and elevation of H1R mRNA in the nasal mucosa of TDI-sensitized rats." | 1.39 | Quercetin inhibits transcriptional up-regulation of histamine H1 receptor via suppressing protein kinase C-δ/extracellular signal-regulated kinase/poly(ADP-ribose) polymerase-1 signaling pathway in HeLa cells. ( Baba, Y; Fukui, H; Hattori, M; Kitamura, Y; Kobayashi, M; Mizuguchi, H; Nakano, T; Ono, S; Sasaki, Y; Takeda, N; Zhang, Q, 2013) |
| "No thrombus was found in the control group." | 1.38 | In vivo MR imaging of plaque disruption and thrombus formation in an atherosclerotic rabbit model. ( Feng, T; Ma, X; Shang, J; Zeng, C; Zhang, Z; Zhao, L; Zhao, Q, 2012) |
| "Pruritus is a severe symptom that is difficult to treat in atopic dermatitis patients." | 1.38 | Red ginseng inhibits scratching behavior associated with atopic dermatitis in experimental animal models. ( Iwao, H; Izumi, Y; Miura, K; Nakao, T; Osada-Oka, M; Samukawa, K; Shiota, M, 2012) |
| "In this work, we used a food allergy model in BALB/c mice to study the cross-reactivity between cow's milk protein (CMP) and soy proteins (SP)." | 1.38 | In vivo evidence of cross-reactivity between cow's milk and soybean proteins in a mouse model of food allergy. ( Candreva, A; Curciarello, R; Docena, GH; Fossati, CA; Petruccelli, S; Rey, MA; Smaldini, P, 2012) |
| "Histamine was also found to damage the dopaminergic neurons in rat substantia nigra." | 1.38 | Histamine- and haloperidol-induced catalepsy in aged mice: differential responsiveness to L-DOPA. ( Ionov, ID; Severtsev, NN, 2012) |
| "An unusual feature of mucolipidosis type IV is constitutive achlorhydria." | 1.37 | A role for the Ca2+ channel TRPML1 in gastric acid secretion, based on analysis of knockout mice. ( Chandra, M; Hofmann, SL; Li, Q; Muallem, S; Soyombo, AA; Zhou, H, 2011) |
| "Clinical studies of gene therapy for hemophilia B revealed the limitations of the intramuscular route, compelling an aggressive approach to the study of scale-independent circulatory means of vector delivery." | 1.37 | Gene transfer to muscle from the isolated regional circulation. ( Bridges, CR; Malik, A; Mead, A; Petrov, M; Stedman, HH, 2011) |
| "Although immunological mechanism of food allergy is well documented, the molecular mechanism(s) involved in food allergen sensitization have not been well characterized." | 1.37 | Mesenteric lymph node transcriptome profiles in BALB/c mice sensitized to three common food allergens. ( Boermans, HJ; Husain, M; Karrow, NA, 2011) |
| "The histamine level was also reduced by EPPF or RA administration in the serum of OVA-sensitized mice." | 1.37 | Effect of Perilla frutescens var. acuta Kudo and rosmarinic acid on allergic inflammatory reactions. ( Ahn, HJ; Kim, HM; Oh, HA; Park, CS; Park, YS, 2011) |
| "Few animal studies of migraine have tested behaviors associated with migraine diagnostic criteria." | 1.37 | Sex differences in behavior and expression of CGRP-related genes in a rodent model of chronic migraine. ( Berman, NE; Gregory, E; Hamilton, ES; He, YY; McCarson, KE; Stucky, NL; Winter, MK, 2011) |
| "Histamine plays major roles in allergic diseases and its action is mediated mainly by histamine H(1) receptor (H1R)." | 1.37 | Albizia lebbeck suppresses histamine signaling by the inhibition of histamine H1 receptor and histidine decarboxylase gene transcriptions. ( Choudhuri, MS; Fukui, H; Hattori, M; Maeyama, K; Mizuguchi, H; Mukherjee, PK; Nurul, IM; Shahriar, M; Takeda, N; Venkatesh, P, 2011) |
| "Histamine is a bioactive amine that exerts immunomodulatory functions, including many allergic symptoms." | 1.37 | TLR-induced activation of neutrophils promotes histamine production via a PI3 kinase dependent mechanism. ( Bryce, PJ; Smuda, C; Wechsler, JB, 2011) |
| "It showed that typical anaphylactoid reactions be caused by histamine phosphate injection on Beagle dogs, and the response of the high-dose group was more obvious than that of the low-dose group." | 1.37 | [Experimental model of histamine-induced anaphylactoid reaction on beagle dogs]. ( Cui, H; Li, Y; Sui, Y; Wang, D; Wang, Z; Yu, Y, 2011) |
| "The histaminergic system plays an important role in memory and learning." | 1.37 | The central histamine level in rat model of vascular dementia. ( Fogel, WA; Kiec-Kononowicz, K; Lazewska, D; Mussur, M; Stasiak, A; Unzeta, M, 2011) |
| "Migraine is a neurovascular disorder that induces debilitating headaches associated with multiple symptoms including facial allodynia, characterized by heightened responsivity to normally innocuous mechanical stimuli." | 1.36 | A novel method for modeling facial allodynia associated with migraine in awake and freely moving rats. ( Brown, K; Ellis, A; Mahoney, J; Maier, SF; McFadden, A; Rezvani, N; Sprunger, D; Watkins, LR; Wieseler, J, 2010) |
| "Histamine is known to increase vascular permeability." | 1.36 | Histamine H1 receptor promotes atherosclerotic lesion formation by increasing vascular permeability for low-density lipoproteins. ( Akhmedov, A; Becher, B; Borén, J; Hofmann, J; Johansen, P; Lüscher, TF; Mocharla, P; Rohrer, L; Rozenberg, I; Sluka, SH; Soliz, J; Steffel, J; Tanner, FC; Watanabe, T, 2010) |
| "Colitis was induced by intrarectal administration of 2,4,6-trinitrobenzene sulfonic acid after 10 days' daily oral administration of EHCG at 100 and 300 mg/kg." | 1.36 | Anti-inflammatory effect of enzymatic hydrolysate of corn gluten in an experimental model of colitis. ( Hasegawa, N; Mochizuki, M; Shigemura, H, 2010) |
| "Pretreatment with naloxone (5 mg/kg) significantly decreased the latency of discomfort produced by the 100 mg/kg dose of MEZZ in the hot plate test." | 1.36 | Antiinflammatory and antinociceptive activities of Zingiber zerumbet methanol extract in experimental model systems. ( Chear, CT; Israf, DA; Mohamad, AS; Sulaiman, MR; Wong, YY; Zakaria, ZA, 2010) |
| "Histamine plays significant roles in the early-phase swelling via H1 receptors, and the late-phase swelling via H3/H4 receptors in this TPA-modified allergic dermatitis model." | 1.35 | Modification of the picryl chloride-induced allergic dermatitis model in mouse ear lobes by 12-O-tetradecanoylphorbol 13-acetate, and analysis of the role of histamine in the modified model. ( Hirasawa, N; Hong, J; Ishihara, K; Katoh, G; Ohsawa, Y; Ohuchi, K; Seyama, T; Shibata, K; Tamura, S, 2009) |
| "As histamine plays a central role in allergic diseases, it is possible that SST affects the allergy-related histamine signaling." | 1.35 | Sho-seiryu-to suppresses histamine signaling at the transcriptional level in TDI-sensitized nasal allergy model rats. ( Das, AK; Dev, S; Fukui, H; Kitamura, Y; Kodama, M; Matsushita, C; Mizuguchi, H; Takeda, N; Umehara, H, 2009) |
| "Histamine content was significantly increased in the hypothalamus, hipocampus, and medulla oblongata." | 1.35 | Histaminergic activity in a rodent model of Parkinson's disease. ( Brus, H; Brus, R; Drab, J; Jochem, J; Körossy, E; Kostrzewa, RM; Noras, L; Nowak, P; Szkilnik, R, 2009) |
| "Pretreatment with scoparone inhibited the calcium uptake and p38 mitogen-activated protein kinase (MAPK) activity." | 1.35 | Anti-allergic effects of scoparone on mast cell-mediated allergy model. ( Choi, YH; Yan, GH, 2009) |
| "These results indicate that congestive heart failure associated with chronic pressure overload induces a differential remodeling of intrinsic cardiac neurons and upregulation of neuronal responsiveness to specific neuromodulators." | 1.35 | Remodeling of the guinea pig intrinsic cardiac plexus with chronic pressure overload. ( Ardell, JL; Baran, CN; Hardwick, JC; Southerland, EM, 2009) |
| "Histamine was fluorometrically assayed by high-performance liquid chromatography." | 1.35 | Effects of multiple dexamethasone treatments on aggravation of allergic conjunctivitis associated with mast cell hyperplasia. ( Fujii, M; Kohno, S; Mizutani, N; Nabe, T; Nagata, T, 2008) |
| "The dimaprit treatment depressed the values to 40-64% of those in the corresponding control group 4-24 hr after reperfusion." | 1.35 | Suppression of ischaemia-induced cytokine release by dimaprit and amelioration of liver injury in rats. ( Adachi, N; Arai, T; Liu, K; Motoki, A; Nagaro, T; Nishibori, M; Takahashi, HK; Yorozuya, T, 2008) |
| "Histamine induced increase in histamine H(1) receptor gene expression in vitro, and the protein kinase C-delta isoform was suggested to mediate the gene expression." | 1.35 | Progress in allergy signal research on mast cells: up-regulation of histamine signal-related gene expression in allergy model rats. ( Fukui, H, 2008) |
| "Olopatadine hydrochloride (olopatadine) is an anti-allergic agent with histamine H1 receptor antagonistic action." | 1.35 | Effect of olopatadine hydrochloride, an anti-histamine drug, on rhinitis induced by intranasal instillation of toluene-2,4-diisocyanate in rats. ( Komai, M; Tamura, T, 2008) |
| "Histamine has an important role in regulation of immune response which is mediated by differential expression of four distinct receptors, H1R-H4R." | 1.34 | Histamine 4 receptor activation induces recruitment of FoxP3+ T cells and inhibits allergic asthma in a murine model. ( Center, DM; Cross, L; Cruikshank, WW; Green, DS; Kornfeld, H; McAllister, B; Morgan, RK, 2007) |
| "Histaminergic agents were given prior and daily for 1, 7 or 14 days after 6-OHDA infusion." | 1.34 | Involvement of brain endogenous histamine in the degeneration of dopaminergic neurons in 6-hydroxydopamine-lesioned rats. ( Chen, Z; Hu, DN; Liu, CQ; Liu, FX; Luo, JH, 2007) |
| "Assessment of peanut hypersensitivity reactions was performed clinically and biologically." | 1.34 | Impact of CD40 ligand, B cells, and mast cells in peanut-induced anaphylactic responses. ( Alvarez, D; Arias, K; Coyle, AJ; Fattouh, R; Goncharova, S; Jordana, M; Kim, B; Reed, J; Sun, J; Walker, T; Waserman, S, 2007) |
| "In a rabbit model of the meconium aspiration syndrome, aminophylline treatment enhanced pulmonary functions and alleviated oxidative injury and changes in airway reactivity related to lung inflammation." | 1.34 | Aminophylline treatment in meconium-induced acute lung injury in a rabbit model. ( Calkovska, A; Mokra, D; Mokry, J; Petraskova, M; Redfors, B; Tatarkova, Z, 2007) |
| "Delayed cerebral vasospasm after subarachnoid hemorrhage (SAH) may be due, in part, to altered regulation of arterial smooth muscle contraction." | 1.33 | Activation of Rho-associated kinase during augmented contraction of the basilar artery to serotonin after subarachnoid hemorrhage. ( Faraci, FM; Heistad, DD; Watanabe, Y, 2005) |
| ") produced a 12-fold shift in the histamine bronchoconstrictor dose-response curve." | 1.33 | Airway closure after antigen challenge in cynomolgus monkeys: effect of the histamine H1 receptor antagonist, chlorpheniramine maleate. ( Celly, CS; Chapman, RW; Hey, JA; House, A; Lamca, JE; Skeans, S, 2005) |
| "BALB/c mice were dosed by intraperitoneally with Ovalbumin, Beef serum albumin, Trypsin inhibitor and Potato acid phosphatase respectively (0." | 1.33 | [Assessment of the BALB/c mice as a suitable animal model for the investigation of food allergy]. ( Guo, YC; Liu, XM; Lü, XZ; Yang, XG, 2005) |
| "Hepatic encephalopathy is characterized by disturbances of motor and cognitive functions involving the basal ganglia." | 1.33 | Deficits in cortico-striatal synaptic plasticity and behavioral habituation in rats with portacaval anastomosis. ( Borsch, E; Doreulee, N; Haas, HL; Häussinger, D; Huston, JP; Kircheis, G; Ponomarenko, AA; Schulz, D; Selbach, O; Sergeeva, OA, 2005) |
| "Athymic bronchial eosinophilia is associated with increased expression of IL-5 and eotaxin mRNA, and with the presence of residual T cells and mast cells." | 1.33 | Nonatopic allergen-independent mast cell activation in parasitized eosinophilic athymic rats. ( Brown, A; Bundick, R; Harper, S; Huntley, J; Mistry, H; Pritchard, DI; Stoten, A, 2005) |
| "Itching is one of the major clinical symptoms in atopic dermatitis (AD) and complicates the management of this pathological condition." | 1.33 | Spontaneous scratching behaviour in DS-Nh mice as a possible model for pruritus in atopic dermatitis. ( Arimura, A; Asakawa, M; Deguchi, M; Hikita, I; Hirasawa, T; Horikawa, T; Matsutani, T; Oku, H; Yoshioka, T, 2006) |
| "The effects on anaphylactic reactions following PN challenge and the association with Ab levels and cytokine profiles were determined." | 1.32 | Engineered recombinant peanut protein and heat-killed Listeria monocytogenes coadministration protects against peanut-induced anaphylaxis in a murine model. ( Bottomly, K; Burks, AW; Huleatt, JW; Li, XM; Sampson, HA; Srivastava, K, 2003) |
| "In conclusion, pulmonary inflammation and peripheral thrombosis are correlated at 6 and 24 hours, but at 1 hour, the prothrombotic effects do not appear to result from pulmonary inflammation but possibly from the blood penetration of DEP-associated components or by DEP particles themselves." | 1.32 | Pulmonary inflammation and thrombogenicity caused by diesel particles in hamsters: role of histamine. ( Hoet, PH; Hoylaerts, MF; Nemery, B; Nemmar, A; Vermylen, J, 2003) |
| "morphine (1 mg/kg)." | 1.32 | The role of central mu opioid receptors in opioid-induced itch in primates. ( Edwards, T; Ko, MC; Lee, H; Naughton, NN; Song, MS, 2004) |
| "In prior work, we reported that, during cataplexy, noradrenergic neurons cease discharge, and serotonergic neurons greatly reduce activity." | 1.32 | Cataplexy-active neurons in the hypothalamus: implications for the role of histamine in sleep and waking behavior. ( Boehmer, LN; John, J; Siegel, JM; Wu, MF, 2004) |
| " This study was performed to investigate the effect of EGF dosage forms on the histamine content of the experimentally induced wound and some wound healing criters in the mice." | 1.32 | The effect of EGF application in gel form on histamine content of experimentally induced wound in mice. ( Babül, A; Dinçer, S; Erdoğan, D; Gönül, B; Ozoğul, C, 2004) |
| "Allergic conjunctivitis was developed by immunization in guinea pigs with a mixture containing Japanese cedar pollen and killed Bordetella pertussis." | 1.31 | Experimental allergic conjunctivitis in guinea pigs induced by Japanese cedar pollen. ( Izushi, K; Kamei, C; Nakahara, H; Sugimoto, Y; Takada, M; Yamada, T, 2000) |
| "Parkinson's disease is a major neurological disorder that primarily affects the nigral dopaminergic cells." | 1.31 | Modulation of histamine H3 receptors in the brain of 6-hydroxydopamine-lesioned rats. ( Anichtchik, OV; Haycock, JW; Huotari, M; Männistö, PT; Panula, P; Peitsaro, N, 2000) |
| "Nonimmunologic anaphylactic reaction was induced by compound 48/80 injection." | 1.31 | Inhibition of immunologic and nonimmunologic stimulation-mediated anaphylactic reactions by water extract of white eggplant (Solanum melongena). ( Chae, HJ; Jeong, HJ; Kim, DK; Kim, HM; Kim, HR; Ku, JY; Lee, YM; Moon, G; Na, HJ, 2001) |
| "To summarize the physicochemical characterization, pharmacokinetic behavior, and biological evaluation of P792, a new monogadolinated MRI blood-pool agent." | 1.31 | Physicochemical and biological evaluation of P792, a rapid-clearance blood-pool agent for magnetic resonance imaging. ( Bonnemain, B; Corot, C; Dencausse, A; Idee, JM; Lancelot, E; Lautrou, J; Meyer, D; Port, M; Raynal, I, 2001) |
| "When histamine was delivered to the alveolar regions, increases in lung resistance appeared to be mediated primarily via the vagus and when delivered to the bronchial airways primarily by its action on smooth muscle or local reflexes." | 1.31 | Bronchial, alveolar, and vascular-induced anaphylaxis and irritant-induced cardiovascular and pulmonary responses. ( Chandra, T; Daza, A; Hameister, WM; Mussatto, DJ; Wong, LB; Yeates, DB, 2001) |
| "The histamine-induced increase in intranasal pressure was significantly augmented after repeated antigen challenge, indicating that nasal hyperresponsiveness was achieved." | 1.31 | Elevated nasal mucosal G protein levels and histamine receptor affinity in a guinea pig model of nasal hyperresponsiveness. ( Chiba, Y; Matsuo, K; Misawa, M; Saitoh, N, 2002) |
| "Histamine was infused i." | 1.30 | Sex, gonads, sex hormones and histamine-stimulated gastric acid and serum pepsinogen. ( Baron, JH, 1997) |
| "Histamine levels were elevated throughout the brain with the greatest increase found in the hypothalamus and in the striatum." | 1.30 | Long-term effects of portacaval anastomosis on the 5-hydroxytryptamine, histamine, and catecholamine neurotransmitter systems in rat brain. ( Belcheva, A; Hippeläinen, M; Kosunen, H; Lozeva, V; MacDonald, E; Tuomisto, L, 1998) |
| "Propranolol was inhaled 20 minutes after an antigen challenge in passively sensitized, anesthetized, and artificially ventilated guinea pigs." | 1.30 | Difference in bronchoprotective effects of bronchodilators on postallergic propranolol-induced bronchoconstriction. ( Fujimura, M; Ishiura, Y; Matsuda, T; Mizuhashi, K; Myou, S, 1999) |
| "Histamine release was measured indirectly as a decrease in tissue-histamine contents (lung, liver, spleen, stomach); histamine formation was estimated directly as an increase in histidine decarboxylase (HDC) activity in the same organs." | 1.29 | Time sequence of histamine release and formation in rat endotoxic shock. ( Garcia-Caballero, M; Lorenz, W; Neugebauer, E; Rixen, D; Scheid, B, 1994) |
| "The inhibition of this pulmonary eosinophilia and bronchial hyperresponsiveness by TRFK-5 was seen for up to 3 mo after treatment." | 1.29 | Effects of an antibody to interleukin-5 in a monkey model of asthma. ( Adams, GK; Chapman, RW; Egan, RW; Fernandez, X; Foran, SK; Kreutner, W; Mauser, PJ; Pitman, AM, 1995) |
| "Treatment with aspirin for 2 or 7 days had no effect on the constrictive responses at the injured site 1 month after injury or on those at the noninjured site at all times examined." | 1.29 | Inhibitory effects of aspirin on coronary hyperreactivity to autacoids after arterial balloon injury in miniature pigs. ( Ibayashi, S; Kuga, T; Ohara, Y; Shimokawa, H; Takeshita, A; Tomoike, H, 1995) |
| "Also, the frequency and amount of thrombus formation were significantly different among all four groups (P < ." | 1.29 | Triggering of plaque disruption and arterial thrombosis in an atherosclerotic rabbit model. ( Abela, GS; Federman, M; Friedl, SE; Gebara, OC; Miyamoto, A; Muller, JE; Picon, PD; Tofler, GH, 1995) |
| "Intratracheal Parainfluenza type 3 (PI-3) virus inoculation of guinea pigs leads to a non-specific airway hyperresponsiveness in vivo and in vitro which coincides with a significant increase in the number of inflammatory cells in the broncho-alveolar lavage fluid (90% increase, 4 days after inoculation)." | 1.29 | Virus-induced airway inflammation and hyperresponsiveness in the guinea-pig is inhibited by levodropropizine. ( Folkerts, G; Nijkamp, FP; Omini, C; van der Linde, HJ, 1993) |
| "Pre-treatment with thioperamide augmented (p < 0." | 1.29 | Histamine forming capacity (HFC) and its modulation by H3 receptor ligands in a model of bronchial hyper-responsiveness. ( Allen, MC; Graham, P; Morris, G, 1996) |
| "The histamine output was markedly reduced by intraperitoneal injection of alpha-fluoromethylhistidine (100 mg/kg), an irreversible inhibitor of histidine decarboxylase, or (R)-alpha-methylhistamine (5 mg/kg), a potent and specific H3-receptor agonist." | 1.28 | Direct evidence for increased continuous histamine release in the striatum of conscious freely moving rats produced by middle cerebral artery occlusion. ( Adachi, N; Itoh, Y; Oishi, R; Saeki, K, 1992) |
| "To investigate the influence of middle ear effusion (MEE) on perilymph (PL), an experimental otitis media with effusion (OME) was manufactured in chinchillas by injecting the tympanic cavity with immune complexes." | 1.28 | Round window membrane and perilymph in experimental otitis media with effusion. ( Fujiyoshi, T; Kawauchi, H; Mogi, G; Suzuki, M, 1989) |
| "Anaphylactic shock was produced in guinea-pigs by sensitizing them with oval albumin and challenging them with an intracardial dose (rapid shock) or intraperitoneal dose (slow shock) of the same protein 4 weeks later." | 1.27 | Histamine, cortisol and organ changes in fatal anaphylactic shock in guinea-pigs. ( Hirvonen, J; Huttunen, P, 1984) |
| "Inflammation was induced by carrageenan, bradykinin, histamine, platelet activating factor and eosinophilotactic factors of lymphocytic or neutrophilic origin." | 1.27 | Experimental eosinophilia and inflammation--the effect of various inflammatory mediators and chemoattractants. ( Auer, H; Egger, D; Fechter, M; Popper, H, 1986) |
| "Isoproterenol responses were determined against a half-maximal methacholine contraction." | 1.27 | Comparison of drug responses in vivo and in vitro in airways of dogs with and without airway hyperresponsiveness. ( Austin, DR; Downes, H; Hirshman, CA; Parks, CM, 1986) |
| " The dose-response relation of the coronary diameter to histamine was not influenced by pretreatment with the nerve transmitter blockers guanethidine (3 X 10(-6) M), atropine (10(-6) M), and tetrodotoxin (3 X 10(-7) M)." | 1.27 | Pathogenesis of coronary artery spasm in miniature swine with regional intimal thickening after balloon denudation. ( Egashira, K; Kawasaki, T; Kobayashi, T; Nakamura, M; Tomoike, H; Yamamoto, Y, 1987) |
| " A dose-response curve to aerosol histamine was constructed by administering histamine aerosols of 0." | 1.27 | Phorbol myristate acetate lung injury and airway responsiveness to aerosol histamine in awake sheep. ( Dyer, EL; Lefferts, PL; Snapper, JR, 1986) |
| "Indomethacin pretreatment did not significantly augment the duodenal lesions induced by mepirizole or cysteamine, but did augment the gastric lesions induced by these compounds." | 1.27 | Augmentation of cysteamine and mepirizole-induced lesions in the rat duodenum and stomach by histamine or indomethacin. ( Kuwahara, Y; Okabe, S; Tanaka, H, 1986) |
| "Histamine was the most potent vasoactive agent, and coronary artery spasm was provoked repeatedly by intracoronary or intravenous administration of histamine in the presence or absence of cimetidine." | 1.27 | Coronary artery spasm induced in miniature swine: angiographic evidence and relation to coronary atherosclerosis. ( Ishii, Y; Nabeyama, S; Nakamura, M; Shimokawa, H; Tanaka, K; Tomoike, H; Yamamoto, H, 1985) |
| "Histamine release was significantly increased in 4 day-vaccinated animals but not 1 or 10 days after vaccination, while broncho-constriction was potentiated in 1 and in 4 day-vaccinated animals." | 1.26 | The effects of Haemophilus influenzae vaccination on anaphylactic mediator release and isoprenaline-induced inhibition of mediator release. ( Nijkamp, FP; Raaijmakers, JA; Schreurs, AJ; Terpstra, GK, 1980) |
| "Serum sickness was induced in rats by a modification of previously described methods avoiding i." | 1.26 | Rat serum sickness: possible role of inflammatory mediators allowing deposition of immune complexes in the glomerular basement membrane. ( Alonso, F; Barat, A; Egido, J; Sánchez-Crespo, M, 1982) |
| "Hemorrhagic hypotension is associated with increased lung water accumulation, secondary to loss of integrity of the alveolar capillary membrane." | 1.26 | The pulmonary alveolar capillary membrane during hemorrhagic hypotension in dogs. ( Fischer, P; Glauser, FL; Millen, JE, 1978) |
| " When aerosol dose-response curves were obtained for these agonists immediately following an "allergic asthmatic" episode, the airways were hyporeactive to PGF2alpha, H, and 5-HT, but not to ACh." | 1.26 | Canine airway responses to acetylcholine, prostaglandin F2alpha, histamine, and serotonin after chronic antigen exposure. ( Chakrin, LW; Christian, P; Giannone, E; Krell, RD; McCoy, J; Osborn, R, 1976) |
| "pertussis, were present in tracheobronchial wash (TBW) by day 15; by day 50, TBW immunodiffusion and immunoelectrophoretic precipitin bands were more intense." | 1.25 | immunoglobulin and histamine-sensitivity response of mice to live Bordetella pertussis. ( Geller, BD; Pittman, M, 1973) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 105 (13.76) | 18.7374 |
| 1990's | 112 (14.68) | 18.2507 |
| 2000's | 187 (24.51) | 29.6817 |
| 2010's | 290 (38.01) | 24.3611 |
| 2020's | 69 (9.04) | 2.80 |
| Authors | Studies |
|---|---|
| Solinski, HJ | 1 |
| Dranchak, P | 1 |
| Oliphant, E | 1 |
| Gu, X | 3 |
| Earnest, TW | 1 |
| Braisted, J | 1 |
| Inglese, J | 1 |
| Hoon, MA | 1 |
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 5 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 1 |
| Nath, A | 1 |
| Cyr, A | 1 |
| Kohut, L | 1 |
| Chambers, L | 1 |
| Stratimirovic, S | 1 |
| Zuckerbraun, B | 1 |
| Li, E | 1 |
| Wang, D | 5 |
| Xue, Y | 1 |
| Yan, J | 1 |
| Wang, J | 10 |
| Shelby, RD | 1 |
| Mar, P | 1 |
| Janzow, GE | 1 |
| Mashburn-Warren, L | 1 |
| Tengberg, N | 1 |
| Navarro, JB | 1 |
| Allen, JM | 1 |
| Wickham, J | 1 |
| Wang, Y | 19 |
| Bailey, MT | 1 |
| Goodman, SD | 1 |
| Besner, GE | 1 |
| Martínez-Gopar, PE | 1 |
| Pérez-Rodríguez, MJ | 1 |
| Rodríguez-Manzo, G | 1 |
| Garduño-Gutierrez, R | 1 |
| Tristán-López, L | 1 |
| Angeles-López, QD | 1 |
| González-Espinosa, C | 1 |
| Pérez-Severiano, F | 1 |
| Zhang, Z | 7 |
| Pan, J | 2 |
| Zhu, T | 1 |
| Malewicz, N | 1 |
| Ye, K | 1 |
| Rong, J | 1 |
| Luo, Y | 1 |
| Situ, Y | 1 |
| Verkhratsky, A | 1 |
| Zhao, J | 2 |
| Tang, D | 1 |
| Nie, H | 1 |
| Wang, S | 3 |
| Wang, L | 5 |
| Hu, H | 3 |
| Dong, P | 1 |
| Malewicz, NM | 1 |
| Ieong, HF | 1 |
| Oeck, S | 1 |
| Kumowski, N | 1 |
| Shimada, SG | 1 |
| LaMotte, RH | 1 |
| Liu, C | 5 |
| Pang, C | 1 |
| Chen, DS | 1 |
| Yi, WQ | 1 |
| Yu, N | 1 |
| Chen, L | 4 |
| Wang, B | 5 |
| Wu, H | 1 |
| Qi, H | 2 |
| Li, H | 8 |
| Pan, L | 2 |
| Li, L | 10 |
| Zhang, K | 1 |
| Yuan, M | 2 |
| Qiu, HJ | 1 |
| Sun, Y | 7 |
| Han, JS | 1 |
| Kim, YL | 1 |
| Yu, HJ | 1 |
| Park, JM | 1 |
| Kim, YJ | 2 |
| Choung, YH | 1 |
| Park, SY | 1 |
| Park, SN | 1 |
| Arora, P | 1 |
| Nainwal, LM | 1 |
| Gupta, G | 1 |
| Singh, SK | 2 |
| Chellappan, DK | 1 |
| Oliver, BG | 1 |
| Dua, K | 1 |
| Huang, WY | 1 |
| Lee, SH | 5 |
| Oh, SJ | 1 |
| Yoon, H | 1 |
| Pan, JH | 1 |
| Jeong, I | 1 |
| Kim, MJ | 4 |
| Han, BK | 1 |
| Kim, JK | 1 |
| Shin, EC | 1 |
| Seugnet, L | 1 |
| Anaclet, C | 1 |
| Perier, M | 1 |
| Ghersi-Egea, JF | 1 |
| Lin, JS | 1 |
| Uda, N | 1 |
| Ogata, S | 1 |
| Yamasaki, N | 1 |
| Miura, S | 1 |
| Hosomi, N | 1 |
| Mori, A | 1 |
| Gotoh, M | 1 |
| Miura, K | 2 |
| Kaminuma, O | 1 |
| Ji, Q | 3 |
| Ren, S | 3 |
| Yonghua, S | 1 |
| Mehrabi Nasab, E | 1 |
| Liuo, Y | 1 |
| Sun, X | 2 |
| Xu, Y | 3 |
| Zhou, J | 4 |
| Jung, MA | 1 |
| Song, HK | 1 |
| Jo, K | 2 |
| Lee, A | 1 |
| Hwang, YH | 1 |
| Ji, KY | 1 |
| Jung, DH | 1 |
| Cai, M | 1 |
| Lee, JY | 4 |
| Pyun, BJ | 1 |
| Kim, T | 1 |
| Taheri, F | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Clinical Study Evaluating the Gastroprotective Effect of Carvedilol in Patients With Ischemic Heart Disease on Aspirin Therapy[NCT05553717] | 66 participants (Anticipated) | Interventional | 2022-10-31 | Not yet recruiting | |||
| Kinetics of IgE Memory B Cells, Plasmablasts and Plasma Cells After Whole Lung Allergen Challenge in Mild Asthmatics[NCT01420003] | 12 participants (Actual) | Interventional | 2011-11-30 | Completed | |||
| A Randomized, Controlled,14-Treatment Day, Multicenter Study to Determine the Optimal Efficacious and Safe Dose of CHF 4226 in a Metered Dose Inhaler in Treating Patients With Chronic Obstructive Pulmonary Disease[NCT00605891] | Phase 2 | 278 participants (Actual) | Interventional | 2006-10-31 | Completed | ||
| Evaluation of the Effect of 2 Weeks Treatment With CHF 4226 pMDI 2µg and 4µg, Given Once Daily in the Morning, on 24-Hour FEV1 in Patients With COPD[NCT00640484] | Phase 2 | 57 participants (Actual) | Interventional | 2008-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
35 reviews available for histamine and Disease Models, Animal
| Article | Year |
|---|---|
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Mast cells in liver disease progression: An update on current studies and implications.
Topics: Animals; Cell Degranulation; Chymases; Disease Models, Animal; Disease Progression; Histamine; Hista | 2022 |
Novel Insight of Histamine and Its Receptor Ligands in Glaucoma and Retina Neuroprotection.
Topics: Animals; Disease Models, Animal; Glaucoma; Histamine; Histamine H3 Antagonists; Humans; Receptors, H | 2021 |
Histamine
Topics: Amine Oxidase (Copper-Containing); Animals; Brain; Brain Diseases; Disease Models, Animal; Disease S | 2019 |
Histaminergic transmission slows progression of amyotrophic lateral sclerosis.
Topics: Amyotrophic Lateral Sclerosis; Animals; Disease Models, Animal; Disease Progression; Gene Expression | 2019 |
Pearls and pitfalls in human pharmacological models of migraine: 30 years' experience.
Topics: Animals; Clinical Trials as Topic; Disease Models, Animal; Drug Evaluation; Histamine; Human Experim | 2013 |
Methods for preclinical assessment of antipruritic agents and itch mechanisms independent of mast-cell histamine.
Topics: Animals; Antipruritics; Disease Models, Animal; Drug Evaluation, Preclinical; Histamine; Humans; Hyp | 2015 |
Critical in vivo roles of histamine and histamine receptor signaling in animal models of metabolic syndrome.
Topics: Animals; Disease Models, Animal; Histamine; Metabolic Syndrome; Receptors, Histamine | 2016 |
Mast cells and histamine metabolism in skin lesions from MRL/MP-lpr/lpr mice.
Topics: Animals; Cell Movement; Disease Models, Animal; Gene Expression Regulation; Histamine; Histamine N-M | 2009 |
Analysis of the mechanism for the development of allergic skin inflammation and the application for its treatment:establishment of a modified allergic dermatitis model in mouse ear lobes by application of 12-O-tetradecanoyl phorbol 13-acetate: putative in
Topics: Animals; Cytokines; Dermatitis, Atopic; Dermatitis, Contact; Disease Models, Animal; Ear; Histamine; | 2009 |
Does the histamine H4 receptor have a pro- or anti-inflammatory role in murine bronchial asthma?
Topics: Animals; Asthma; Disease Models, Animal; Histamine; Humans; Indoles; Inflammation; Mice; Piperazines | 2010 |
Histamine and H3 receptor in alcohol-related behaviors.
Topics: Alcohol Drinking; Alcoholism; Animals; Disease Models, Animal; Ethanol; Histamine; Histidine Decarbo | 2011 |
[Roles of histamine in the exacerbated allergic dermatitis].
Topics: Animals; Cyclosporine; Dermatitis, Atopic; Disease Models, Animal; Drug Therapy, Combination; Histam | 2011 |
Nutrient-induced inflammation in the intestine.
Topics: Amine Oxidase (Copper-Containing); Animals; Dietary Fats; Disease Models, Animal; Histamine; Inflamm | 2011 |
The role of histamine in asthma.
Topics: Animals; Asthma; Disease Models, Animal; Histamine; Histamine Antagonists; Humans; Immune System; Lu | 2010 |
[Effect of diesel particles on allergic inflammatory response: cellular targets and molecular mechanisms].
Topics: Animals; Basophils; Bronchial Hyperreactivity; Chemokines; Cytokines; Disease Models, Animal; Fibros | 2002 |
Histamine decreases E-cadherin-based adhesion to increase permeability of human airway epithelium.
Topics: Animals; Asthma; Cadherins; Cell Membrane Permeability; Disease Models, Animal; Guinea Pigs; Histami | 2003 |
A review of the properties of spiradoline: a potent and selective kappa-opioid receptor agonist.
Topics: Analgesia; Analgesics; Animals; Cardiovascular System; Cocaine-Related Disorders; Disease Models, An | 2003 |
Motility and allergy.
Topics: Animals; Cholinergic Agents; Disease Models, Animal; Food Hypersensitivity; Gastrointestinal Motilit | 2005 |
Peptide immunotherapy for allergic diseases using a rice-based edible vaccine.
Topics: Administration, Oral; Allergens; Animals; Antigens, Plant; Cell Proliferation; Cryptomeria; Cytokine | 2006 |
[Inducible histamine protects mice from hepatitis through H2-receptor stimulation].
Topics: Animals; Disease Models, Animal; Hepatitis; Histamine; Humans; Lipopolysaccharides; Mice; Propioniba | 2008 |
Experimental asthma in guinea pigs revisited.
Topics: Anaphylaxis; Animals; Antibody Formation; Antigen-Antibody Reactions; Antigens; Asthma; Conditioning | 1984 |
Animal models of chronic pain: their possible validation from human experience with posterior rhizotomy and congenital analgesia (Part I of the second John J. Bonica lecture).
Topics: Adolescent; Adult; Animals; Child; Child, Preschool; Chronic Disease; Cordotomy; Disease Models, Ani | 1981 |
Inflammation and airway reactivity.
Topics: Aerosols; Animals; Asthma; Disease Models, Animal; Dogs; Endotoxins; Granulocytes; Guinea Pigs; Hist | 1984 |
Pathogenesis of diencephalic lesions in an experimental model of Wernicke's encephalopathy.
Topics: Animals; Brain Damage, Chronic; Diencephalon; Disease Models, Animal; Dizocilpine Maleate; Energy Me | 1995 |
Linkage homology for bronchial hyperresponsiveness between DNA markers on human chromosome 5q31-q33 and mouse chromosome 13.
Topics: Animals; Asthma; Atracurium; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstric | 1995 |
Hypothalamic neuronal histamine: implications of its homeostatic control of energy metabolism.
Topics: Adaptation, Physiological; Animals; Body Temperature Regulation; Circadian Rhythm; Cytokines; Diseas | 1997 |
[Analysis of chemical mediators involved in acute inflammatory reaction with the rat pleurisy model].
Topics: Animals; Arachidonic Acid; Capillary Permeability; Carrageenan; Cell Movement; Chemokines; Complemen | 1997 |
[Possibilities and limitations of the use of rat paw edemas as models of inflammation. 1. Review on edemas as models and their possible use].
Topics: Animals; Anti-Inflammatory Agents; Bradykinin; Carrageenan; Cell Migration Inhibition; Dextrans; Dis | 1975 |
Experimental stress ulcers: a review.
Topics: Animals; Bacterial Infections; Burns; Catecholamines; Cold Temperature; Disease Models, Animal; Gast | 1975 |
Experimental induction of spasm, sudden progression of organic stenosis and intramural hemorrhage in the epicardial coronary arteries.
Topics: Angina Pectoris, Variant; Animals; Coronary Disease; Coronary Vasospasm; Coronary Vessels; Disease M | 1991 |
H1- and H2-antagonists in allergic and pseudoallergic diseases.
Topics: Anaphylaxis; Animals; Contrast Media; Disease Models, Animal; Drug Therapy, Combination; Histamine; | 1990 |
Human hypersensitivity angiitis.
Topics: Animals; Antigen-Antibody Complex; Complement System Proteins; Disease Models, Animal; Histamine; Hu | 1989 |
Autonomic imbalance in asthma with special reference to beta adrenergic blockade.
Topics: Acetylcholine; Adenylyl Cyclases; Adrenergic alpha-Antagonists; Animals; Asthma; Blood Glucose; Brad | 1972 |
4 trials available for histamine and Disease Models, Animal
| Article | Year |
|---|---|
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
The 2S albumin allergens of Arachis hypogaea, Ara h 2 and Ara h 6, are the major elicitors of anaphylaxis and can effectively desensitize peanut-allergic mice.
Topics: 2S Albumins, Plant; Anaphylaxis; Animals; Antigens, Plant; Arachis; Basophils; Desensitization, Immu | 2012 |
[Optimization of hepatoprotective therapy of viral hepatitis with consideration of neuromediatory link of pathogenesis].
Topics: 11-Hydroxycorticosteroids; Acute Disease; Adult; Animals; Catecholamines; Chemical and Drug Induced | 2006 |
726 other studies available for histamine and Disease Models, Animal
| Article | Year |
|---|---|
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S | 2019 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
Circulating Metabolomic Analysis following Cecal Ligation and Puncture in Young and Aged Mice Reveals Age-Associated Temporal Shifts in Nicotinamide and Histidine/Histamine Metabolic Pathways.
Topics: Age Factors; Animals; Cecum; Disease Models, Animal; Histamine; Histidine; Ligation; Male; Metabolom | 2021 |
The Protective Role of Cirsilineol against Ovalbumin-Induced Allergic Rhinitis in Mice by Suppression of Inflammation and Oxidative Stress.
Topics: Animals; Anti-Allergic Agents; Biomarkers; Carrier Proteins; Cells, Cultured; Disease Models, Animal | 2021 |
Antibacterial and anti-inflammatory effects of Lactobacillus reuteri in its biofilm state contribute to its beneficial effects in a rat model of experimental necrotizing enterocolitis.
Topics: Animals; Animals, Newborn; Anti-Bacterial Agents; Anti-Inflammatory Agents; Biofilms; Disease Models | 2022 |
Mast cells and histamine are involved in the neuronal damage observed in a quinolinic acid-induced model of Huntington's disease.
Topics: Animals; Disease Models, Animal; Female; Histamine; Huntington Disease; Mast Cells; Mice; Mice, Inbr | 2022 |
Oxymatrine screened from Sophora flavescens by cell membrane immobilized chromatography relieves histamine-independent itch.
Topics: Alkaloids; Animals; Antipruritics; Cell Membrane; Chloroquine; Chromatography; Disease Models, Anima | 2021 |
MiR-224 ameliorates inflammation and symptoms in mouse model of allergic rhinitis by targeting CDK9.
Topics: Animals; Cyclin-Dependent Kinase 9; Cytokines; Disease Models, Animal; Histamine; Immunoglobulin E; | 2021 |
Punctate Administration of Ficin as a human and animal model of non-histaminergic itch.
Topics: Animals; Disease Models, Animal; Ficain; Histamine; Humans; Mice; Pain; Pruritus | 2022 |
Topics: Allergens; Animals; Cytokines; Disease Models, Animal; Histamine; Mice; Mice, Inbred BALB C; Nasal M | 2022 |
Histamine Is Responsible for the Neuropathic Itch Induced by the Pseudorabies Virus Variant in a Mouse Model.
Topics: Animals; Disease Models, Animal; Herpesvirus 1, Suid; Histamine; Mammals; Mice; Pruritus; Pseudorabi | 2022 |
Safety and efficacy of intratympanic histamine injection as an adjuvant to dexamethasone in a noise-induced murine model.
Topics: Adjuvants, Immunologic; Adjuvants, Pharmaceutic; Animals; Dexamethasone; Disease Models, Animal; His | 2022 |
Orally administered solasodine, a steroidal glycoalkaloid, suppresses ovalbumin-induced exaggerated Th2-immune response in rat model of bronchial asthma.
Topics: Allergens; Aluminum Hydroxide; Animals; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Dexamethaso | 2022 |
Topics: Alum Compounds; Animals; Asthma; Bronchoalveolar Lavage Fluid; Canavalia; Cytokines; Dexamethasone; | 2022 |
A marked enhancement of a BLOC-1 gene, pallidin, associated with somnolent mouse models deficient in histamine transmission.
Topics: Animals; Carrier Proteins; Disease Models, Animal; Histamine; Lectins; Mice | 2023 |
Re-evaluation of over-the-counter histamine H1-receptor antagonists based on their effects on murine models of allergen-induced nasal hyperresponsiveness.
Topics: Allergens; Animals; Disease Models, Animal; Histamine; Histamine H1 Antagonists; Loratadine; Mice | 2022 |
Bufotalin ameliorates ovalbumin-induced allergic rhinitis by restoring the Tregs.
Topics: Animals; Cytokines; Disease Models, Animal; Histamine; Immunoglobulin E; Interleukin-10; Mice; Mice, | 2023 |
Bufotalin ameliorates ovalbumin-induced allergic rhinitis by restoring the Tregs.
Topics: Animals; Cytokines; Disease Models, Animal; Histamine; Immunoglobulin E; Interleukin-10; Mice; Mice, | 2023 |
Bufotalin ameliorates ovalbumin-induced allergic rhinitis by restoring the Tregs.
Topics: Animals; Cytokines; Disease Models, Animal; Histamine; Immunoglobulin E; Interleukin-10; Mice; Mice, | 2023 |
Bufotalin ameliorates ovalbumin-induced allergic rhinitis by restoring the Tregs.
Topics: Animals; Cytokines; Disease Models, Animal; Histamine; Immunoglobulin E; Interleukin-10; Mice; Mice, | 2023 |
Effect of Temperature and Humidity on the Allegro-inflammatory Factors and Allergic Rhinitis-related Behavior.
Topics: Animals; Disease Models, Animal; Histamine; Humidity; Immunoglobulin E; Interleukin-4; Leukotriene C | 2022 |
DPP4 Inhibitor Sitagliptin Reduces Inflammatory Responses and Mast Cell Activation in Allergic Rhinitis.
Topics: Animals; Cytokines; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Anim | 2023 |
Gleditsia sinensis Lam. aqueous extract attenuates nasal inflammation in allergic rhinitis by inhibiting MUC5AC production through suppression of the STAT3/STAT6 pathway.
Topics: Animals; Cytokines; Disease Models, Animal; Gleditsia; Histamine; Humans; Immunoglobulin E; Inflamma | 2023 |
Amelioration of cognition impairments in the valproic acid-induced animal model of autism by ciproxifan, a histamine H3-receptor antagonist.
Topics: Animals; Autism Spectrum Disorder; Autistic Disorder; Behavior, Animal; Cognition; Cognitive Dysfunc | 2023 |
Ready vascular permeability of a near-infrared fluorescent agent ASP5354 for intraoperative ureteral identification enables imaging of carcinoma tissues.
Topics: Animals; Capillary Permeability; Carcinoma; Coloring Agents; Disease Models, Animal; Esophageal Neop | 2023 |
Crisaborole Inhibits Itch and Pain by Preventing Neutrophil Infiltration in a Mouse Model of Atopic Dermatitis.
Topics: Animals; Calcium; Capsaicin; Chloroquine; Dermatitis, Atopic; Disease Models, Animal; Histamine; Neu | 2023 |
Potential anti-inflammatory effect of Madi-Ryuk and its active ingredient tannic acid on allergic rhinitis.
Topics: Animals; Anti-Inflammatory Agents; Caspase 1; Chemokine CXCL2; Cytokines; Disease Models, Animal; Eo | 2019 |
Red Algae Sulfated Polysaccharides Effervescent Tablets Attenuated Ovalbumin-Induced Anaphylaxis by Upregulating Regulatory T cells in Mouse Models.
Topics: Anaphylaxis; Animals; Anti-Allergic Agents; Disease Models, Animal; Female; Histamine; Humans; Immun | 2019 |
Coumarin alleviates ovalbumin-induced food anaphylaxis in a mouse model by affecting mast cell function.
Topics: Anaphylaxis; Animals; Anti-Allergic Agents; Cell Line; Coumarins; Disease Models, Animal; Female; Fo | 2019 |
[Establishment of new evaluation standards for systemic anaphylactoid reactions using mouse model].
Topics: Anaphylaxis; Animals; Disease Models, Animal; Drugs, Chinese Herbal; Histamine; Immunoglobulin E; In | 2019 |
Investigation of the preliminary mechanism of action for the acute anti-inflammatory activity of the methanol extract of Smilax ornata Lem.
Topics: Animals; Anti-Inflammatory Agents; Bradykinin; Dinoprostone; Disease Models, Animal; Edema; Histamin | 2020 |
A natural mouse model reveals genetic determinants of systemic capillary leak syndrome (Clarkson disease).
Topics: Animals; Capillary Leak Syndrome; Capillary Permeability; Chromosome Mapping; Disease Models, Animal | 2019 |
In vivo characterization of histological and immunological response of allergic protein of Metapenaeus dobsonii using an adjuvant free BALB/c mice model.
Topics: Adjuvants, Immunologic; Allergens; Anaphylaxis; Animals; Disease Models, Animal; Duodenum; Female; F | 2020 |
Effect of transglutaminase cross-linking on the allergenicity of tofu based on a BALB/c mouse model.
Topics: Allergens; Animals; Chymases; Cytokines; Disease Models, Animal; Female; Glycine max; Histamine; Imm | 2020 |
Histamine H
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic Neurons; Animals; Benzimidazoles; Clonidine; Diseas | 2020 |
I. inflexus (Thunb.) Kudo extract improves atopic dermatitis and depressive-like behavior in DfE-induced atopic dermatitis-like disease.
Topics: Animals; Behavior, Animal; Cell Line; Corticosterone; Cytokines; Depression; Dermatitis, Atopic; Der | 2020 |
Fermented
Topics: Animals; Anti-Inflammatory Agents; Cytokines; Dermatitis, Atopic; Dinitrochlorobenzene; Disease Mode | 2020 |
GPER-mediated, oestrogen-dependent visceral hypersensitivity in stressed rats is associated with mast cell tryptase and histamine expression.
Topics: Abdominal Pain; Animals; Cell Degranulation; Colon; Disease Models, Animal; Estradiol; Female; Hista | 2020 |
Histamine receptor agonist alleviates severe cardiorenal damages by eliciting anti-inflammatory programming.
Topics: Animals; Anti-Inflammatory Agents; Disease Models, Animal; Heart; Heart Failure; Histamine; Histamin | 2020 |
Effect of probiotics in experimental otitis media with effusion.
Topics: Animals; Disease Models, Animal; Ear, Middle; Histamine; Male; Neutrophils; Otitis Media with Effusi | 2020 |
Biliary damage and liver fibrosis are ameliorated in a novel mouse model lacking l-histidine decarboxylase/histamine signaling.
Topics: Animals; Cholangitis, Sclerosing; Disease Models, Animal; Histamine; Histidine Decarboxylase; Liver; | 2020 |
The inhibitory activity of alginate against allergic reactions in an ovalbumin-induced mouse model.
Topics: Alginates; Animals; Anti-Allergic Agents; Disease Models, Animal; Duodenum; Egg Hypersensitivity; Fe | 2020 |
Exploration of sensory and spinal neurons expressing gastrin-releasing peptide in itch and pain related behaviors.
Topics: Animals; Disease Models, Animal; Gastrin-Releasing Peptide; Gene Knockout Techniques; Histamine; Mic | 2020 |
Peanut applied to the skin of nonhuman primates induces antigen-specific IgG but not IgE.
Topics: Allergens; Anaphylaxis; Animals; Arachis; Chlorocebus aethiops; Disease Models, Animal; Female; Hist | 2020 |
A novel MRGPRX2-targeting antagonistic DNA aptamer inhibits histamine release and prevents mast cell-mediated anaphylaxis.
Topics: Amino Acid Sequence; Anaphylaxis; Animals; Aptamers, Nucleotide; Cell Line; Computer Simulation; Dis | 2020 |
Apigenin Inhibits Histamine-Induced Cervical Cancer Tumor Growth by Regulating Estrogen Receptor Expression.
Topics: Animals; Apigenin; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Enzyme-Linked Immun | 2020 |
Nootkatone Inhibits Acute and Chronic Inflammatory Responses in Mice.
Topics: Acute-Phase Reaction; Animals; Anti-Inflammatory Agents; Capillary Permeability; Carrageenan; Cotton | 2020 |
Protective effect of Asarum sieboldii essential oil on ovalbumin induced allergic rhinitis in rat.
Topics: Animals; Anti-Allergic Agents; Asarum; Behavior, Animal; Cytokines; Disease Models, Animal; Drugs, C | 2020 |
Topics: Animals; beta-Defensins; Cell Movement; Cells, Cultured; Culture Media; Disease Models, Animal; Fema | 2020 |
Impact of histamine H4 receptor deficiency on the modulation of T cells in a murine breast cancer model.
Topics: Animals; Breast Neoplasms; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Disease Models, A | 2021 |
Therapeutic Potential of Antileukotriene Drug-
Topics: Animals; Anti-Asthmatic Agents; Antioxidants; Area Under Curve; Asthma; Camellia sinensis; Delayed-A | 2021 |
Effect of resolvins on sensitisation of TRPV1 and visceral hypersensitivity in IBS.
Topics: Adult; Animals; Capsaicin; Disease Models, Animal; Docosahexaenoic Acids; Eicosapentaenoic Acid; Ent | 2021 |
Bovine β-lactoglobulin-induced passive systemic anaphylaxis model using humanized NOG hIL-3/hGM-CSF transgenic mice.
Topics: Anaphylaxis; Animals; Basophils; Cattle; Disease Models, Animal; Epinephrine; Granulocyte-Macrophage | 2021 |
Perampanel attenuates scratching behavior induced by acute or chronic pruritus in mice.
Topics: Animals; Behavior, Animal; Chloroquine; Cyclopropanes; Disease Models, Animal; Histamine; Hypodermoc | 2020 |
Region-specific regulation of central histaminergic H3 receptor expression in a mouse model of cow's milk allergy.
Topics: Animals; Brain; Disease Models, Animal; Female; Gene Expression Regulation; Histamine; Intestine, Sm | 2020 |
Viridicatol Isolated from Deep-Sea
Topics: Anaphylaxis; Animals; Anti-Allergic Agents; Aquatic Organisms; B-Lymphocytes; beta-N-Acetylhexosamin | 2020 |
Histamine 2 Receptor Agonism and Histamine 4 Receptor Antagonism Ameliorate Inflammation in a Model of Psoriasis.
Topics: Animals; Disease Models, Animal; Histamine; Imiquimod; Inflammation; Mice; Mice, Inbred BALB C; Psor | 2020 |
DM-induced Hypermethylation of IR and IGF1R attenuates mast cell activation and airway responsiveness in rats.
Topics: Allergens; Animals; Asthma; Biomarkers; Bronchial Hyperreactivity; Cytokines; Diabetes Mellitus, Exp | 2020 |
Nevadensin relieves food allergic responses and passive cutaneous anaphylaxis in mice through inhibiting the expression of c-Kit receptors.
Topics: Animals; beta-N-Acetylhexosaminidases; Cell Line; Cell Proliferation; Cell Survival; Cytokines; Dise | 2020 |
Targeting presynaptic H3 heteroreceptor in nucleus accumbens to improve anxiety and obsessive-compulsive-like behaviors.
Topics: Afferent Pathways; Animals; Anxiety Disorders; Disease Models, Animal; Glutamates; Histamine; Histam | 2020 |
Administration of Lactobacillus paracasei HB89 mitigates PM2.5-induced enhancement of inflammation and allergic airway response in murine asthma model.
Topics: Animals; Asthma; Cytokines; Disease Models, Animal; Down-Regulation; Female; Histamine; Immunoglobul | 2020 |
Herb pair of Ephedrae Herba-Armeniacae Semen Amarum alleviates airway injury in asthmatic rats.
Topics: Acetylcholine; Animals; Apoptosis; Asthma; Disease Models, Animal; Drugs, Chinese Herbal; Ephedra si | 2021 |
A basophil-neuronal axis promotes itch.
Topics: Acute Disease; Allergens; Animals; Basophils; Chronic Disease; Dermatitis, Atopic; Disease Models, A | 2021 |
The role of pruriceptors in enhancing sensitivity to pruritogens in a murine chronic compression model of dorsal root ganglion.
Topics: Animals; Calcium; Capsaicin; Cattle; Chronic Disease; Disease Models, Animal; Ganglia, Spinal; Hista | 2021 |
Causative role of mast cell and mast cell-regulatory function of disialyllacto-N-tetraose in necrotizing enterocolitis.
Topics: Adolescent; Animals; Animals, Newborn; Cathepsin C; Child; Child, Preschool; Chymases; Cytokines; Di | 2021 |
Integrated metabolomics and network pharmacology approach to exploring the potential mechanism of tianxiang capsule for treating motion sickness.
Topics: Acetylcholine; Animals; Disease Models, Animal; Drugs, Chinese Herbal; Histamine; Hormones; Male; Me | 2021 |
Conditional Deletions of
Topics: Anaphylaxis; Animals; Cells, Cultured; Circadian Rhythm; Disease Models, Animal; Encephalomyelitis, | 2021 |
Exposure of ovalbumin during pregnancy prevents the development of allergic rhinitis in offspring through the induction of mast cell autophagy.
Topics: Allergens; Animals; Autophagy; Disease Models, Animal; Female; Histamine; Humans; Immunity, Maternal | 2021 |
Comparison of allergenicity among cow, goat, and horse milks using a murine model of atopy.
Topics: Administration, Oral; Allergens; Animals; Cattle; Cytokines; Disease Models, Animal; Female; Goats; | 2021 |
Histamine Ingestion by
Topics: Animals; Anopheles; Disease Models, Animal; Female; Histamine; Host-Parasite Interactions; Malaria; | 2021 |
Human histamine H
Topics: Animals; Arrhythmias, Cardiac; Cimetidine; Dimaprit; Disease Models, Animal; Heart Atria; Heart Vent | 2021 |
Surfactin exerts an anti-cancer effect through inducing allergic reactions in melanoma skin cancer.
Topics: Amino Acid Sequence; Animals; Anti-Allergic Agents; Antineoplastic Agents; Apoptosis; Cell Degranula | 2021 |
Pharmacological evaluation of the gabapentin salicylaldehyde derivative, gabapentsal, against tonic and phasic pain models, inflammation, and pyrexia.
Topics: Aldehydes; Analgesics; Animals; Anti-Inflammatory Agents; Antipyretics; Carrageenan; Disease Models, | 2021 |
Yiqi Jiemin decoction alleviates allergic rhinitis in a guinea pig model by suppressing inflammation, restoring Th1/Th2 balance, and improving cellular metabolism.
Topics: Animals; Anti-Inflammatory Agents; Biomarkers; Carrier Proteins; Cytokines; Disease Models, Animal; | 2021 |
Immunomodulation and mechanisms of fucoidan from Cladosiphon okamuranus ameliorates atopic dermatitis symptoms.
Topics: Administration, Oral; Animals; Cell Death; Cell Degranulation; Cytokines; Dermatitis, Atopic; Dinitr | 2021 |
Metabolomics analysis of anaphylactoid reaction reveals its mechanism in a rat model.
Topics: Allergens; Anaphylaxis; Animals; Arachidonic Acid; Citric Acid; Disease Models, Animal; Histamine; H | 2017 |
Mentha arvensis essential oil suppressed airway changes induced by histamine and ovalbumin in experimental animals.
Topics: Animals; Asthma; Bronchoconstriction; Disease Models, Animal; Dyspnea; Eosinophils; Female; Guinea P | 2018 |
Histamine therapeutic efficacy in metastatic melanoma: Role of histamine H4 receptor agonists and opportunity for combination with radiation.
Topics: Animals; Antineoplastic Agents; Biomarkers; Cell Line, Tumor; Cell Proliferation; Cellular Senescenc | 2017 |
Anti-inflammatory effect of epigallocatechin gallate in a mouse model of ovalbumin-induced allergic rhinitis.
Topics: Allergens; Animals; Anti-Inflammatory Agents; Catechin; Cyclooxygenase 2; Cytokines; Disease Models, | 2017 |
Citrus tachibana Leaves Ethanol Extract Alleviates Airway Inflammation by the Modulation of Th1/Th2 Imbalance via Inhibiting NF-κB Signaling and Histamine Secretion in a Mouse Model of Allergic Asthma.
Topics: Animals; Anti-Asthmatic Agents; Asthma; Citrus; Disease Models, Animal; Histamine; Humans; Immunoglo | 2017 |
Disrupted functional connectivity between the periaqueductal gray and other brain regions in a rat model of recurrent headache.
Topics: Animals; Bradykinin; Brain; Brain Mapping; Dinoprostone; Disease Models, Animal; Histamine; Inflamma | 2017 |
The potential protective role of taurine against experimental allergic inflammation.
Topics: Animals; Caspase 1; Cell Line; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; | 2017 |
Carvedilol can attenuate histamine-induced paw edema and formaldehyde-induced arthritis in rats without risk of gastric irritation.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Arthritis, Rheumatoid; Carbazoles; Carve | 2017 |
Mast Cells Granular Contents Are Crucial for Deep Vein Thrombosis in Mice.
Topics: Adoptive Transfer; Animals; Blood Coagulation; Blood Platelets; Cell Degranulation; Cells, Cultured; | 2017 |
Increased Sleep Need and Reduction of Tuberomammillary Histamine Neurons after Rodent Traumatic Brain Injury.
Topics: Animals; Brain; Brain Injuries, Traumatic; Disease Models, Animal; Histamine; Male; Neurons; Rats; R | 2018 |
Role of mast cells in bronchial contraction in nonallergic obstructive lung pathology.
Topics: Adenosine; Animals; Bronchi; Bronchial Hyperreactivity; Bronchoconstriction; Cell Degranulation; Cro | 2017 |
Boron neutron capture therapy (BNCT) translational studies in the hamster cheek pouch model of oral cancer at the new "B2" configuration of the RA-6 nuclear reactor.
Topics: Animals; Boron Neutron Capture Therapy; Cheek; Cricetinae; Disease Models, Animal; Histamine; Mouth | 2017 |
Skullcapflavone II attenuates ovalbumin-induced allergic rhinitis through the blocking of Th2 cytokine production and mast cell histamine release.
Topics: Allergens; Animals; Anti-Inflammatory Agents; Cytokines; Disease Models, Animal; Flavonoids; Histami | 2017 |
Anti‑allergic action of bacillus Calmette‑Guerin extract in experimental mast cell‑mediated anaphylactic models.
Topics: Animals; Anti-Allergic Agents; Anti-Asthmatic Agents; Bacillus; Cell Degranulation; Disease Models, | 2017 |
Mesenchymal stromal cells ameliorate acute allergic rhinitis in rats.
Topics: Acute Disease; Animals; Cells, Cultured; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; | 2017 |
Anti‑inflammatory effect of Amomum xanthioides in a mouse atopic dermatitis model.
Topics: Amomum; Animals; Anti-Inflammatory Agents; Cell Line; Dermatitis, Atopic; Disease Models, Animal; Hi | 2017 |
Distinct roles of NMB and GRP in itch transmission.
Topics: Animals; Antipruritics; Behavior, Animal; Capsaicin; Disease Models, Animal; Gastrin-Releasing Pepti | 2017 |
Rutinosylated Ferulic Acid Attenuates Food Allergic Response and Colitis by Upregulating Regulatory T Cells in Mouse Models.
Topics: Animals; Chromatography, High Pressure Liquid; Colitis; Coumaric Acids; Dendritic Cells; Dextran Sul | 2017 |
Role of thalamic ventral posterolateral nucleus histamine H
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Disease Models, Animal; Formaldehyde; Histamine; Hist | 2017 |
Opposing effects of bronchopulmonary C-fiber subtypes on cough in guinea pigs.
Topics: Action Potentials; Adenosine; Animals; Bradykinin; Citric Acid; Cough; Disease Models, Animal; Guine | 2018 |
Influence of glucocorticoids on time-of-day-dependent variations in IgE-, histamine-, and platelet-activating factor-mediated systemic anaphylaxis in different mouse strains.
Topics: Anaphylaxis; Animals; Circadian Rhythm; Disease Models, Animal; Glucocorticoids; Histamine; Immunogl | 2018 |
Cooling Relief of Acute and Chronic Itch Requires TRPM8 Channels and Neurons.
Topics: Animals; Antipruritics; Behavior, Animal; Capsaicin; Chloroquine; Chronic Disease; Cryotherapy; Dise | 2018 |
Comprehensive characterization of neurochemicals in three zebrafish chemical models of human acute organophosphorus poisoning using liquid chromatography-tandem mass spectrometry.
Topics: Acetylcholine; Animals; Chromatography, High Pressure Liquid; Disease Models, Animal; Dopamine; Epin | 2018 |
Nebivolol attenuates oxidative stress and inflammation in a guinea pig model of ovalbumin-induced asthma: a possible mechanism for its favorable respiratory effects.
Topics: Animals; Anti-Asthmatic Agents; Asthma; Biomarkers; Bronchoalveolar Lavage Fluid; Disease Models, An | 2018 |
FcγR/ROS/CK2α Is the Key Inducer of NF-κB Activation in a Murine Model of Asthma.
Topics: Allergens; Animals; Asthma; Casein Kinase II; Cytokines; Disease Models, Animal; Female; Histamine; | 2018 |
Histamine drives severity of innate inflammation via histamine 4 receptor in murine experimental colitis.
Topics: Adolescent; Adult; Aged; Animals; Cells, Cultured; Colitis; Colitis, Ulcerative; Colon; Dextran Sulf | 2018 |
New mechanism underlying IL-31-induced atopic dermatitis.
Topics: Adult; Animals; Brain-Derived Neurotrophic Factor; Case-Control Studies; Cytokines; Dermatitis, Atop | 2018 |
What we know (and don't know) about the biology and functions of mast cells and basophils.
Topics: Anaphylaxis; Animals; Basophils; Cell Communication; Cell Degranulation; Diagnostic Imaging; Disease | 2018 |
Different perception levels of histamine-induced itch sensation in young adult mice.
Topics: Age Factors; Animals; Body Weight; Calcium; Cells, Cultured; Disease Models, Animal; Ganglia, Spinal | 2018 |
Bamboo salt suppresses skin inflammation in mice with 2, 4-dinitrofluorobenzene-induced atopic dermatitis.
Topics: Animals; Caspase 1; Dermatitis, Atopic; Dinitrofluorobenzene; Disease Models, Animal; Female; Histam | 2018 |
Potentiation of skin TSLP production by a cosmetic colorant leads to aggravation of dermatitis symptoms.
Topics: Animals; Azo Compounds; Benzenesulfonates; Cell Line; Coloring Agents; Cytokines; Dermatitis, Atopic | 2018 |
GPCR Kinase (GRK)-2 Is a Key Negative Regulator of Itch: l-Glutamine Attenuates Itch via a Rapid Induction of GRK2 in an ERK-Dependent Way.
Topics: Animals; Cell Line; Chloroquine; Dermatitis, Contact; Dinitrochlorobenzene; Disease Models, Animal; | 2018 |
Deep-Sea-Derived Butyrolactone I Suppresses Ovalbumin-Induced Anaphylaxis by Regulating Mast Cell Function in a Murine Model.
Topics: 4-Butyrolactone; Anaphylaxis; Animals; Aspergillus; Cells, Cultured; Disease Models, Animal; Female; | 2018 |
Mast cells contribute to Enterovirus 71 infection-induced pulmonary edema in neonatal mice.
Topics: Animals; Animals, Newborn; Brain; Cytokines; Disease Models, Animal; Enterovirus A, Human; Enterovir | 2018 |
Stratification of peanut allergic murine model into anaphylaxis severity risk groups using thermography.
Topics: Allergens; Anaphylaxis; Animals; Arachis; Disease Models, Animal; Female; Histamine; Intradermal Tes | 2018 |
Enhanced central histaminergic transmission attenuates compulsive-like behavior in mice.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Compulsive Behavior; Disease Models, Animal; Dose-R | 2018 |
The anti-inflammatory effects of erythromycin, clarithromycin, azithromycin and roxithromycin on histamine-induced otitis media with effusion in guinea pigs.
Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Azithromycin; Clarithromycin; Disease Mode | 2018 |
[Establishment of vulnerable plaque model by mast cell activation in adventitia and evaluation of effectiveness of intervention of Shenlian tablet].
Topics: Adventitia; Animals; Atorvastatin; C-Reactive Protein; Cell Degranulation; Diet, High-Fat; Disease M | 2016 |
Modulation of Itch by Localized Skin Warming and Cooling.
Topics: Animals; Antipruritics; Body Temperature Regulation; Dermatitis, Atopic; Disease Models, Animal; His | 2018 |
Regulatory effects of chrysophanol, a bioactive compound of AST2017-01 in a mouse model of 2,4-dinitrofluorobenzene-induced atopic dermatitis.
Topics: Animals; Anthraquinones; Cordyceps; Cytokines; Dermatitis, Atopic; Dinitrofluorobenzene; Disease Mod | 2018 |
LASSBio-1586, an N-acylhydrazone derivative, attenuates nociceptive behavior and the inflammatory response in mice.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Carrage | 2018 |
The behavioral study on the interactive aggravation between pruritus and depression.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Chloroquine; Depression; Depressive Disorder; Dise | 2018 |
Cordycepin ameliorates skin inflammation in a DNFB-challenged murine model of atopic dermatitis.
Topics: Administration, Cutaneous; Animals; Anti-Inflammatory Agents; Deoxyadenosines; Dermatitis, Atopic; D | 2018 |
Effects of RNA interference-mediated E-selectin gene silencing on cell adhesion molecule expression and cell-cell adhesion in vascular endothelial cells in mice with immunologic contact urticaria.
Topics: Animals; Cell Adhesion; Cell Line, Tumor; Disease Models, Animal; E-Selectin; Endothelial Cells; End | 2019 |
Geraniol suppresses proinflammatory mediators in phorbol 12-myristate 13-acetate with A23187-induced HMC-1 cells.
Topics: Acyclic Monoterpenes; Animals; Anti-Allergic Agents; Anti-Inflammatory Agents, Non-Steroidal; Calcim | 2018 |
Fluorine-containing lupane triterpenoid acid derivatives: Design, synthesis and biological evaluation as potential anti-inflammatory agents.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Betulinic Acid; Concanavalin A; Disease Models, Ani | 2019 |
Non-Histaminergic Itch Mediators Elevated in the Skin of a Porcine Model of Scabies and of Human Scabies Patients.
Topics: Aged; Animals; Biomarkers; Biopsy; Disease Models, Animal; Female; Histamine; Humans; Immunohistoche | 2019 |
Histamine-4 receptor antagonist JNJ7777120 inhibits pro-inflammatory microglia and prevents the progression of Parkinson-like pathology and behaviour in a rat model.
Topics: alpha-Synuclein; Animals; Behavior, Animal; Brain; Corpus Striatum; Disease Models, Animal; Disease | 2019 |
Chronic histamine 3 receptor antagonism alleviates depression like conditions in mice via modulation of brain-derived neurotrophic factor and hypothalamus-pituitary adrenal axis.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain; Brain-Derived Neurotrophic Factor; Corticos | 2019 |
Distinct roles of histamine H1- and H2-receptor signaling pathways in inflammation-associated colonic tumorigenesis.
Topics: Animals; Carcinogenesis; Colon; Disease Models, Animal; Gastrointestinal Microbiome; Histamine; Hist | 2019 |
Coptisine Suppresses Mast Cell Degranulation and Ovalbumin-Induced Allergic Rhinitis.
Topics: Animals; Berberine; beta-N-Acetylhexosaminidases; Cell Degranulation; Cell Line; Disease Models, Ani | 2018 |
Inherent allergic potential of α-dioxygenase fragment: A pathogenesis related protein.
Topics: Allergens; Animals; Biomarkers; Cytokines; Dioxygenases; Disease Models, Animal; Disease Susceptibil | 2019 |
Bacterial secretion of histamine within the gut influences immune responses within the lung.
Topics: Animals; Bacteria; Bacterial Physiological Phenomena; Disease Models, Animal; Escherichia coli; Gast | 2019 |
In vitro and in vivo performance of epinastine hydrochloride-releasing contact lenses.
Topics: Animals; Conjunctivitis, Allergic; Contact Lenses, Hydrophilic; Delayed-Action Preparations; Dibenza | 2019 |
Morphological and functional analysis of beige (Chèdiak-Higashi syndrome) mouse mast cells with giant granules.
Topics: Animals; Cell Degranulation; Cells, Cultured; Chediak-Higashi Syndrome; Cytoplasmic Granules; Diseas | 2019 |
Berberine suppresses mast cell-mediated allergic responses via regulating FcɛRI-mediated and MAPK signaling.
Topics: Animals; Anti-Allergic Agents; Berberine; beta-N-Acetylhexosaminidases; Cell Degranulation; Cell Lin | 2019 |
Experimental autoimmune myocarditis in rats and therapeutic histamine H1 - H4 receptor inhibition.
Topics: Animals; Autoimmune Diseases; Disease Models, Animal; Heart; Histamine; Histamine Antagonists; Ligan | 2018 |
Attenuation of allergic responses following treatment with resveratrol in anaphylactic models and IgE-mediated mast cells.
Topics: Abies; Animals; Anti-Allergic Agents; B-Lymphocytes; beta-N-Acetylhexosaminidases; Cell Line; Diseas | 2019 |
Signal Transducer and Activator of Transcription 3 in Keratinocytes Regulates Histaminergic Itch but Not Nonhistaminergic Itch.
Topics: Animals; Chloroquine; Disease Models, Animal; Female; Histamine; Keratinocytes; Male; Mice, Knockout | 2019 |
Enhanced histamine-induced itch in diacylglycerol kinase iota knockout mice.
Topics: Animals; Behavior, Animal; Calcium; Diacylglycerol Kinase; Disease Models, Animal; Female; Ganglia, | 2019 |
Histamine modulates hippocampal inflammation and neurogenesis in adult mice.
Topics: Animals; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; Disks Large Homolog 4 | 2019 |
Lupane-type conjugates with aminoacids, 1,3,4- oxadiazole and 1,2,5-oxadiazole-2-oxide derivatives: Synthesis, anti-inflammatory activity and in silico evaluation of target affinity.
Topics: Amino Acids; Animals; Anti-Inflammatory Agents; Computer Simulation; Concanavalin A; Disease Models, | 2019 |
Histamine Is an Inducer of the Heat Shock Response in SOD1-G93A Models of ALS.
Topics: Amyotrophic Lateral Sclerosis; Animals; Astrocytes; Cell Death; Dendritic Spines; Disease Models, An | 2019 |
Lymphatic diamine oxidase secretion stimulated by fat absorption is linked with histamine release.
Topics: Amine Oxidase (Copper-Containing); Animals; Dietary Fats; Disease Models, Animal; Duodenum; Emulsion | 2013 |
Photodynamic treatment of oral squamous cell carcinoma in hamster cheek pouch model using chlorin p6-histamine conjugate.
Topics: Animals; Carcinoma, Squamous Cell; Cell Line, Tumor; Cheek; Cricetinae; Disease Models, Animal; Hist | 2013 |
Antigen-induced airway hyperresponsiveness in absence of broncho-obstruction in sensitized guinea pigs.
Topics: Airway Obstruction; Animals; Antigens; Asthma; Bronchoalveolar Lavage Fluid; Disease Models, Animal; | 2013 |
Neutrophil-infiltrated paw edema induced by mannose-binding Dioclea violacea lectin.
Topics: Animals; Anti-Inflammatory Agents; Binding Sites; Cytokines; Dexamethasone; Dioclea; Disease Models, | 2013 |
Assessment of pain and itch behavior in a mouse model of neurofibromatosis type 1.
Topics: Animals; Capsaicin; Chloroquine; Constriction; Disease Models, Animal; Functional Laterality; Histam | 2013 |
Genomic and non-genomic effects of glucocorticoids on allergic rhinitis model in mice.
Topics: Adenosine Triphosphate; Animals; Behavior, Animal; Cinnamates; Disease Models, Animal; Estrenes; Fem | 2013 |
Activity-dependent silencing reveals functionally distinct itch-generating sensory neurons.
Topics: Action Potentials; Anesthetics, Local; Animals; Antipruritics; Antirheumatic Agents; Behavior, Anima | 2013 |
[Normative research on bacteriostasis and relieving itching external therapeutic function of kochiae fructus].
Topics: Administration, Cutaneous; Animals; Anti-Bacterial Agents; Antipruritics; Arthrodermataceae; Bassia | 2012 |
Involvement of chymase in allergic conjunctivitis of guinea pigs.
Topics: Allergens; Animals; Chymases; Conjunctivitis, Allergic; Disease Models, Animal; Enzyme Inhibitors; G | 2013 |
Time-course analysis of counts and degranulation of mast cells during early intestinal ischemia-reperfusion injury in mice.
Topics: Animals; Cell Degranulation; Disease Models, Animal; Histamine; Intestinal Mucosa; Intestines; Male; | 2013 |
Greatly increased numbers of histamine cells in human narcolepsy with cataplexy.
Topics: Adult; Aged, 80 and over; Animals; Brain; Cataplexy; Cell Count; Disease Models, Animal; Dogs; Femal | 2013 |
Polydatin attenuated food allergy via store-operated calcium channels in mast cell.
Topics: Animals; Calcium; Calcium Channels; Disease Models, Animal; Drugs, Chinese Herbal; Female; Food Hype | 2013 |
Role of histidine/histamine in carnosine-induced neuroprotection during ischemic brain damage.
Topics: Animals; Astrocytes; Brain Ischemia; Carnosine; Disease Models, Animal; Histamine; Histidine; Male; | 2013 |
Complement C5A antagonist treatment improves the acute circulatory and inflammatory consequences of experimental cardiac tamponade.
Topics: Animals; Cardiac Tamponade; Complement C5a; Disease Models, Animal; Endothelin-1; Female; Hemodynami | 2013 |
Increase of histaminergic tuberomammillary neurons in narcolepsy.
Topics: Aged; Aged, 80 and over; Animals; Ataxin-3; Cell Count; Disease Models, Animal; Female; Histamine; H | 2013 |
Intranasal curcumin and its evaluation in murine model of asthma.
Topics: Administration, Intranasal; Animals; Anti-Asthmatic Agents; Asthma; Bronchoalveolar Lavage Fluid; Ce | 2013 |
Effect of hyperthermia on histamine blood level and convulsive behavior in infant rats.
Topics: Animals; Animals, Newborn; Anti-Asthmatic Agents; Body Temperature; Cromolyn Sodium; Disease Models, | 2013 |
Evaluation of the effect of kaempferol in a murine allergic rhinitis model.
Topics: Animals; Anti-Allergic Agents; Caspase 1; Cell Line; Cytokines; Disease Models, Animal; Enzyme Activ | 2013 |
Anaphylactic responses to histamine in mice utilize both histamine receptors 1 and 2.
Topics: Anaphylaxis; Animals; Antibody Specificity; Disease Models, Animal; Histamine; Immunoglobulin E; Mic | 2013 |
Lactobacillus reuteri-specific immunoregulatory gene rsiR modulates histamine production and immunomodulation by Lactobacillus reuteri.
Topics: Animals; Artificial Gene Fusion; Colitis; Cytokines; Disease Models, Animal; Gene Expression Regulat | 2013 |
Effects of ovalbumin glycoconjugates on alleviation of orally induced egg allergy in mice via dendritic-cell maturation and T-cell activation.
Topics: Administration, Oral; Animals; Chymases; Dendritic Cells; Disease Models, Animal; Egg Hypersensitivi | 2014 |
Inhibition of IL-32 and TSLP production through the attenuation of caspase-1 activation in an animal model of allergic rhinitis by Naju Jjok (Polygonum tinctorium).
Topics: Administration, Oral; Animals; Caspase 1; Cell Line; Chemokine CXCL2; Cyclooxygenase 2; Cytokines; D | 2014 |
Histamine receptors expressed in circulating progenitor cells have reciprocal actions in ligation-induced arteriosclerosis.
Topics: Animals; Arteriosclerosis; Chemokine CCL2; Disease Models, Animal; Histamine; Histidine Decarboxylas | 2013 |
Sex-related differences in SLIGRL-induced pruritus in mice.
Topics: Acute Disease; Animals; Behavior, Animal; Chronic Disease; Disease Models, Animal; Female; Histamine | 2014 |
Antiallergic effects of pigments isolated from green sea urchin (Strongylocentrotus droebachiensis) shells.
Topics: Animal Shells; Animals; Anti-Allergic Agents; Conjunctivitis, Allergic; Dibenzoxepins; Disease Model | 2013 |
Bronchoprotection by olodaterol is synergistically enhanced by tiotropium in a guinea pig model of allergic asthma.
Topics: Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Animals; Animals, Outbred Strains; | 2014 |
Suppression of 2,4-dinitrochlorobenzene-induced atopic dermatitis by extract of Bacillus Calmette-Guerin.
Topics: Animals; BCG Vaccine; Cell Extracts; Dermatitis, Atopic; Dinitrochlorobenzene; Disease Models, Anima | 2014 |
Behavioral anxiolysis without reduction of hippocampal theta frequency after histamine application in the lateral septum of rats.
Topics: Anesthetics, Intravenous; Animals; Anti-Anxiety Agents; Anxiety Disorders; Buspirone; Disease Models | 2014 |
IgE-mediated mast cell responses are inhibited by thymol-mediated, activation-induced cell death in skin inflammation.
Topics: Anaphylaxis; Animals; Apoptosis; Calcium; Cell Death; Cell Degranulation; Cell Survival; Dermatitis; | 2014 |
Placental restriction of fetal growth reduces cutaneous responses to antigen after sensitization in sheep.
Topics: Age Factors; Animals; Antibodies, Bacterial; Antigens; Bacterial Vaccines; Birth Weight; Clostridium | 2014 |
High-intensity swimming exercise increases dust mite extract and 1-chloro-2,4-dinitrobenzene-derived atopic dermatitis in BALB/c mice.
Topics: Animals; Dermatitis, Atopic; Dinitrochlorobenzene; Disease Models, Animal; Epidermis; Female; Histam | 2014 |
Behavioral model of itch, alloknesis, pain and allodynia in the lower hindlimb and correlative responses of lumbar dorsal horn neurons in the mouse.
Topics: Action Potentials; Animals; Capsaicin; Disease Models, Animal; Electrophysiology; Hindlimb; Histamin | 2014 |
Mechanism of the histamine H(3) receptor-mediated increase in exploratory locomotor activity and anxiety-like behaviours in mice.
Topics: Animals; Anxiety; Biogenic Monoamines; Brain; Disease Models, Animal; Enzyme Inhibitors; Exploratory | 2014 |
Histamine H4 and H1 receptors contribute to postinflammatory visceral hypersensitivity.
Topics: Animals; Cetirizine; Colitis; Colonoscopy; Convalescence; Disease Models, Animal; Histamine; Histami | 2014 |
Systemic delivery of alpha-asarone with Kolliphor HS 15 improves its safety and therapeutic effect on asthma.
Topics: Allylbenzene Derivatives; Anaphylaxis; Animals; Anisoles; Anti-Asthmatic Agents; Asthma; Biological | 2015 |
Surfactant-induced chronic pruritus: Role of L-histidine decarboxylase expression and histamine production in epidermis.
Topics: Animals; Behavior, Animal; Disease Models, Animal; Enzyme Induction; Epidermis; Histamine; Histamine | 2014 |
Artemisia capillaris inhibits atopic dermatitis-like skin lesions in Dermatophagoides farinae-sensitized Nc/Nga mice.
Topics: Animals; Anti-Inflammatory Agents; Artemisia; Cell Line; Dermatitis, Atopic; Dermatophagoides farina | 2014 |
In vitro smooth muscle contractility before and after relief of experimental obstruction in the rat: application to the surgical management of ileal dilatation.
Topics: Acetylcholine; Animals; Dilatation, Pathologic; Disease Models, Animal; Electric Stimulation; Gastro | 2014 |
Peripheral antinociception and anti-inflammatory effects of sulphated polysaccharides from the alga Caulerpa mexicana.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Caulerpa; Dextrans; Disease Models, Anim | 2014 |
Extracellular signal-regulated kinase (ERK) activation is required for itch sensation in the spinal cord.
Topics: Animals; Butadienes; Chloroquine; Dinitrofluorobenzene; Disease Models, Animal; Enzyme Activation; E | 2014 |
Antigen 43/Fcε3 chimeric protein expressed by a novel bacterial surface expression system as an effective asthma vaccine.
Topics: Adhesins, Escherichia coli; Adoptive Transfer; Animals; Antibodies, Neutralizing; Asthma; Autoantibo | 2014 |
Morus alba L. suppresses the development of atopic dermatitis induced by the house dust mite in NC/Nga mice.
Topics: Animals; Chemokine CCL17; Dermatitis, Atopic; Disease Models, Animal; Histamine; Humans; Immunoglobu | 2014 |
Nalfurafine suppresses pruritogen- and touch-evoked scratching behavior in models of acute and chronic itch in mice.
Topics: Animals; Antipruritics; Behavior, Animal; Chloroquine; Disease Models, Animal; Histamine; Ichthyosis | 2015 |
The therapeutic potential of histamine receptor ligands in inflammatory bowel disease.
Topics: Animals; Colitis; Disease Models, Animal; Histamine; Humans; Immune System; Inflammatory Bowel Disea | 2014 |
Curine inhibits mast cell-dependent responses in mice.
Topics: Allergens; Animals; Anti-Allergic Agents; Brazil; Disease Models, Animal; Histamine; Hypersensitivit | 2014 |
Histamine upregulates Nav1.8 expression in primary afferent neurons via H2 receptors: involvement in neuropathic pain.
Topics: Animals; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Famotidine; Gang | 2014 |
Salvia plebeia suppresses atopic dermatitis-like skin lesions.
Topics: Administration, Oral; Animals; Camphanes; Cells, Cultured; Cytokines; Dermatitis, Atopic; Disease Mo | 2014 |
Hemokinin-1 mediates pruriceptive processing in the rat spinal cord.
Topics: Animals; Disease Models, Animal; Formaldehyde; Histamine; Immunohistochemistry; Male; Nociception; P | 2014 |
Unique immunomodulatory effects of azelastine on dendritic cells in vitro.
Topics: Animals; Anti-Allergic Agents; Cell Proliferation; Dendritic Cells; Dermatitis, Allergic Contact; Di | 2014 |
Suppression of peritoneal thickening by histamine in a mouse model of peritoneal scraping.
Topics: Animals; Disease Models, Animal; Histamine; Histamine Agonists; Histamine Antagonists; Injections, I | 2015 |
Brain serotonin content regulates the manifestation of tramadol-induced seizures in rats: disparity between tramadol-induced seizure and serotonin syndrome.
Topics: Animals; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Histamine; Male; Rats; Rat | 2015 |
Communication between mast cells and rat submucosal neurons.
Topics: Animals; Calcium Signaling; Cells, Cultured; Coculture Techniques; Colon; Disease Models, Animal; En | 2015 |
Histamine acting on the basolateral amygdala reverts the impairment of aversive memory of rats submitted to neonatal maternal deprivation.
Topics: Analysis of Variance; Animals; Avoidance Learning; Basolateral Nuclear Complex; Dimaprit; Disease Mo | 2015 |
Rational Design and Synthesis of Benzamides as Non-ulcerogenic Anti-inflammatory Agents.
Topics: Animals; Benzamides; Binding Sites; Carbon-13 Magnetic Resonance Spectroscopy; Carrageenan; Cyclooxy | 2015 |
Efficient immuno-modulation of TH1/TH2 biomarkers in 2,4-dinitrofluorobenzene-induced atopic dermatitis: nanocarrier-mediated transcutaneous co-delivery of anti-inflammatory and antioxidant drugs.
Topics: Administration, Cutaneous; Animals; Anti-Inflammatory Agents; Antioxidants; Biomarkers; Cytokines; D | 2014 |
C-reactive protein specifically enhances platelet-activating factor-induced inflammatory activity in vivo.
Topics: Animals; C-Reactive Protein; Disease Models, Animal; Edema; Histamine; Inflammation Mediators; Male; | 2014 |
Centrally injected histamine increases posterior hypothalamic acetylcholine release in hemorrhage-hypotensive rats.
Topics: Acetylcholine; Animals; Blood Pressure; Chlorpheniramine; Choline; Disease Models, Animal; Dose-Resp | 2015 |
Enhancement of ionizing radiation response by histamine in vitro and in vivo in human breast cancer.
Topics: Animals; Antioxidants; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cellular Senescence; Disease M | 2015 |
CCL22/Macrophage-derived Chemokine Expression in Apolipoprotein E-deficient Mice and Effects of Histamine in the Setting of Atherosclerosis.
Topics: Animals; Apolipoproteins E; Atherosclerosis; Cells, Cultured; Chemokine CCL22; Disease Models, Anima | 2015 |
Role of adrenocorticotropic hormone in the modulation of pollinosis induced by pollen antigens.
Topics: Adrenocorticotropic Hormone; Animals; Antigens, Plant; Cell Differentiation; Disease Models, Animal; | 2015 |
The histamine H4 -receptor (H4 R) regulates eosinophilic inflammation in ovalbumin-induced experimental allergic asthma in mice.
Topics: Adoptive Transfer; Allergens; Animals; Asthma; Bronchoalveolar Lavage Fluid; CD11c Antigen; Cytokine | 2015 |
Anti-allergic effect of intranasal administration of type-A procyanidin polyphenols based standardized extract of cinnamon bark in ovalbumin sensitized BALB/c mice.
Topics: Administration, Intranasal; Animals; Anti-Allergic Agents; Biflavonoids; Catechin; Cinnamomum zeylan | 2015 |
Estrogen increases the severity of anaphylaxis in female mice through enhanced endothelial nitric oxide synthase expression and nitric oxide production.
Topics: Anaphylaxis; Animals; Body Temperature; Capillary Permeability; Disease Models, Animal; Estradiol; E | 2015 |
Protein kinase Cδ mediates histamine-evoked itch and responses in pruriceptors.
Topics: Animals; beta-Alanine; Calcitonin Gene-Related Peptide; Calcium; Capsaicin; Cells, Cultured; Chloroq | 2015 |
Histamine restores biliary mass following carbon tetrachloride-induced damage in a cholestatic rat model.
Topics: Animals; Apoptosis; Bile Ducts; Bile Ducts, Intrahepatic; Carbon Tetrachloride; Cell Proliferation; | 2015 |
The mast cell stabilizer sodium cromoglycate reduces histamine release and status epilepticus-induced neuronal damage in the rat hippocampus.
Topics: Analysis of Variance; Animals; Anti-Asthmatic Agents; Anticonvulsants; Cell Count; Chromatography, H | 2015 |
Novel function of histamine signaling in hyperlipidemia-induced atherosclerosis: Histamine H1 receptors protect and H2 receptors accelerate atherosclerosis.
Topics: Animals; Atherosclerosis; Blotting, Western; Chromatography, High Pressure Liquid; Disease Models, A | 2015 |
LPS exacerbates functional and inflammatory responses to ovalbumin and decreases sensitivity to inhaled fluticasone propionate in a guinea pig model of asthma.
Topics: Administration, Inhalation; Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid | 2015 |
Histamine promotes locomotion recovery after spinal cord hemisection via inhibiting astrocytic scar formation.
Topics: Animals; Astrocytes; Cicatrix; Disease Models, Animal; Female; Histamine; Histamine Agonists; Histid | 2015 |
Role of the complement anaphylatoxin C5a-receptor pathway in atopic dermatitis in mice.
Topics: Animals; Complement C5a; Dermatitis, Atopic; Dinitrochlorobenzene; Disease Models, Animal; Gene Expr | 2015 |
Histamine suppresses regulatory T cells mediated by TGF-β in murine chronic allergic contact dermatitis.
Topics: Animals; Chronic Disease; Dermatitis, Allergic Contact; Disease Models, Animal; Female; Histamine; H | 2015 |
Bencycloquidium bromide inhibits nasal hypersecretion in a rat model of allergic rhinitis.
Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Cytokines; Disease Models, Animal; Histamine; Male | 2015 |
A fungal protease allergen provokes airway hyper-responsiveness in asthma.
Topics: Administration, Inhalation; Allergens; Animals; Aspergillus fumigatus; Asthma; Bacterial Proteins; B | 2015 |
Antiallergic effect of piperine on ovalbumin-induced allergic rhinitis in mice.
Topics: Acetates; Alkaloids; Animals; Anti-Allergic Agents; Benzodioxoles; Biomarkers; Cell Degranulation; C | 2015 |
Brain Histamine Is Crucial for Selective Serotonin Reuptake Inhibitors' Behavioral and Neurochemical Effects.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Antidepressive Agents; Brain; Citalopram; Cyclic AM | 2015 |
Inhibition of the mammalian target of rapamycin complex 1 signaling pathway reduces itch behaviour in mice.
Topics: Animals; Disease Models, Animal; Gastrin-Releasing Peptide; Histamine; Hypoglycemic Agents; Male; Me | 2015 |
Histamine reduces boron neutron capture therapy-induced mucositis in an oral precancer model.
Topics: Animals; Boron Neutron Capture Therapy; Cricetinae; Disease Models, Animal; Histamine; Indoles; Mout | 2015 |
In the brain of mice, 3-iodothyronamine (T1AM) is converted into 3-iodothyroacetic acid (TA1) and it is included within the signaling network connecting thyroid hormone metabolites with histamine.
Topics: Animals; Avoidance Learning; Behavior, Animal; Biotransformation; Disease Models, Animal; Hippocampu | 2015 |
Combination histamine and serotonin treatment after simulated childbirth injury improves stress urinary incontinence.
Topics: Animals; Birth Injuries; Disease Models, Animal; Electromyography; Female; Histamine; Nerve Crush; P | 2016 |
Histamine H3 receptor antagonist decreases cue-induced alcohol reinstatement in mice.
Topics: Alcohol Deterrents; Alcohol Drinking; Alcohol-Related Disorders; Animals; Azepines; Conditioning, Op | 2016 |
Gamma-Terpinene Modulates Acute Inflammatory Response in Mice.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cyclohexane Mon | 2015 |
Effect of systemic clarithromycin and prednisolone on histamine-induced otitis media in guinea pigs.
Topics: Animals; Anti-Bacterial Agents; Clarithromycin; Cytokines; Disease Models, Animal; Dose-Response Rel | 2015 |
Histamine deficiency exacerbates myocardial injury in acute myocardial infarction through impaired macrophage infiltration and increased cardiomyocyte apoptosis.
Topics: Acute Disease; Animals; Apoptosis; Cell Line; Cimetidine; Creatine Kinase, MB Form; Disease Models, | 2015 |
IL-17 producing mast cells promote the expansion of myeloid-derived suppressor cells in a mouse allergy model of colorectal cancer.
Topics: Amino Acid Sequence; Animals; Colorectal Neoplasms; Disease Models, Animal; Female; Histamine; Hyper | 2015 |
Desloratadine citrate disodium injection, a potent histamine H(1) receptor antagonist, inhibits chemokine production in ovalbumin-induced allergic rhinitis guinea pig model and histamine-induced human nasal epithelial cells via inhibiting the ERK1/2 and N
Topics: Animals; Anti-Allergic Agents; Cells, Cultured; Chemokine CCL2; Chemokine CCL5; Chemokines; Disease | 2015 |
A novel benzofuran, 4-methoxybenzofuran-5-carboxamide, from Tephrosia purpurea suppressed histamine H1 receptor gene expression through a protein kinase C-δ-dependent signaling pathway.
Topics: Animals; Anti-Allergic Agents; Benzofurans; Cytokines; Disease Models, Animal; Gene Expression Regul | 2016 |
Mast cells and histamine alter intestinal permeability during malaria parasite infection.
Topics: Animals; Coinfection; Disease Models, Animal; Female; Histamine; Histamine Antagonists; Macaca mulat | 2016 |
Histamine H2 Receptor-Mediated Suppression of Intestinal Inflammation by Probiotic Lactobacillus reuteri.
Topics: Animals; Colitis; Colon; Diet; Disease Models, Animal; Gastrointestinal Microbiome; Histamine; Histi | 2015 |
Dermatological evaluation of counter irritant effect of methanol leaf extract of Rumexvesicarius Linn. in rabbits.
Topics: Animals; Anti-Inflammatory Agents; Dermatitis, Irritant; Disease Models, Animal; Disinfectants; Dose | 2016 |
A Herbal Formula, Atofreellage, Ameliorates Atopic Dermatitis-Like Skin Lesions in an NC/Nga Mouse Model.
Topics: Animals; Cytokines; Dermatitis, Atopic; Dinitrochlorobenzene; Disease Models, Animal; Histamine; Imm | 2015 |
Characterization of various types of mast cells derived from model mice of familial gastrointestinal stromal tumors with KIT-Asp818Tyr mutation.
Topics: Animals; Blotting, Western; Bone Marrow Cells; Disease Models, Animal; Gastrointestinal Neoplasms; G | 2015 |
Spinal histamine in attenuation of mechanical hypersensitivity in the spinal nerve ligation-induced model of experimental neuropathy.
Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Histamine; Hyperalgesia; Ligation | 2016 |
Involvement of TRPV4 in Serotonin-Evoked Scratching.
Topics: Animals; Behavior, Animal; Disease Models, Animal; Histamine; Immunohistochemistry; Injections, Intr | 2016 |
Treatment with olopatadine and naphazoline hydrochloride reduces allergic conjunctivitis in mice through alterations in inflammation, NGF and VEGF.
Topics: Animals; Blotting, Western; Conjunctivitis, Allergic; Cytokines; Disease Models, Animal; Drug Therap | 2016 |
Dexamethasone attenuates echinococcosis-induced allergic reactions via regulatory T cells in mice.
Topics: Anaphylaxis; Animals; Antibodies, Helminth; Antibody Specificity; Antigens, Helminth; Cytokines; Dex | 2016 |
Topical Application of Fingolimod Perturbs Cutaneous Inflammation.
Topics: Administration, Topical; Animals; Capillary Permeability; Cell Movement; Cells, Cultured; Cytokines; | 2016 |
Pulmonary liposomal formulations encapsulated procaterol hydrochloride by a remote loading method achieve sustained release and extended pharmacological effects.
Topics: Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Animals; Bronchoconstriction; Chemi | 2016 |
Evidence for Dynamic Network Regulation of Drosophila Photoreceptor Function from Mutants Lacking the Neurotransmitter Histamine.
Topics: Animals; Animals, Genetically Modified; Blindness; Dark Adaptation; Disease Models, Animal; Drosophi | 2016 |
Histamine H3 receptor antagonists display antischizophrenic activities in rats treated with MK-801.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Disease Models, Animal; Dizocilpine Maleate; Histam | 2016 |
Investigation of peanut oral immunotherapy with CpG/peanut nanoparticles in a murine model of peanut allergy.
Topics: Allergens; Animals; Arachis; Cytokines; Desensitization, Immunologic; Disease Models, Animal; Female | 2016 |
Allergic inflammation is augmented via histamine H4 receptor activation: The role of natural killer cells in vitro and in vivo.
Topics: Animals; Chemokine CCL17; Chemotaxis; Coculture Techniques; Dendritic Cells; Dermatitis, Atopic; Dis | 2016 |
4-Aminopyridine, A Blocker of Voltage-Dependent K+ Channels, Restores Blood Pressure and Improves Survival in the Wistar Rat Model of Anaphylactic Shock.
Topics: 4-Aminopyridine; Acidosis; Anaphylaxis; Animals; Blood Pressure; Dinoprost; Dinoprostone; Disease Mo | 2016 |
Histamine Receptor 2 is Required to Suppress Innate Immune Responses to Bacterial Ligands in Patients with Inflammatory Bowel Disease.
Topics: Adult; Animals; Case-Control Studies; Cells, Cultured; Colitis, Ulcerative; Crohn Disease; Cytokines | 2016 |
Evaluation of the anti-inflammatory effects of volatile oils from processed products of Angelica sinensis radix by GC-MS-based metabolomics.
Topics: Angelica sinensis; Animals; Anti-Inflammatory Agents; Biomarkers; Carrageenan; Dinoprostone; Disease | 2016 |
Histaminergic Pharmacology Modulates the Analgesic and Antiedematogenic Effects of Spinally Injected Morphine.
Topics: Analgesics, Opioid; Animals; Anti-Inflammatory Agents; Carrageenan; Cetirizine; Disease Models, Anim | 2016 |
[Establishment of a rat model of oral food allergy].
Topics: Animals; Disease Models, Animal; Food Hypersensitivity; Histamine; Immunoglobulin E; Male; Ovalbumin | 2016 |
Contribution of mast cells to injury mechanisms in a mouse model of pediatric traumatic brain injury.
Topics: Animals; Brain Contusion; Brain Injuries, Traumatic; Caspase 3; Cell Death; Cells, Cultured; Child, | 2016 |
Specific histamine binding activity of a new lipocalin from Hyalomma asiaticum (Ixodidae) and therapeutic effects on allergic asthma in mice.
Topics: Animals; Asthma; Cloning, Molecular; Disease Models, Animal; DNA, Complementary; Escherichia coli; G | 2016 |
Xinqin exhibits the anti-allergic effect through the JAK2/STAT5 signaling pathway.
Topics: Animals; Anti-Allergic Agents; Calcimycin; Cell Degranulation; Cell Line; Disease Models, Animal; Do | 2016 |
Inhibitory effects of norlignans isolated from Anemarrhena asphodeloides on degranulation of rat basophilic leukemia- 2H3Cells.
Topics: Anaphylaxis; Anemarrhena; Animals; Anti-Allergic Agents; Cell Degranulation; Cell Line, Tumor; Disea | 2016 |
Innocuous warming enhances peripheral serotonergic itch signaling and evokes enhanced responses in serotonin-responsive dorsal horn neurons in the mouse.
Topics: Action Potentials; Afferent Pathways; Animals; Calcium Signaling; Disease Models, Animal; Ganglia, S | 2017 |
Peculiarities of Blood Flow Changes in Venae Cavae during Experimental Pulmonary Embolism.
Topics: Animals; Blood Flow Velocity; Cardiac Output; Disease Models, Animal; Histamine; Humans; Injections, | 2016 |
β-eudesmol suppresses allergic reactions via inhibiting mast cell degranulation.
Topics: Anaphylaxis; Animals; Anti-Allergic Agents; Cell Degranulation; Cell Line; Cytokines; Disease Models | 2017 |
Gastroprotective and ulcer healing effects of hydroethanolic extract of leaves of Caryocar coriaceum: Mechanisms involved in the gastroprotective activity.
Topics: Animals; Antioxidants; Capsaicin; Chromatography, High Pressure Liquid; Chronic Disease; Disease Mod | 2017 |
In Vitro and In Vivo Anti-Allergic and Anti-Inflammatory Effects of eBV, a Newly Developed Derivative of Bee Venom, through Modulation of IRF3 Signaling Pathway in a Carrageenan-Induced Edema Model.
Topics: Animals; Bee Venoms; Blotting, Western; Carrageenan; Chromatography, High Pressure Liquid; Dinoprost | 2016 |
The Pathogenesis of Alcohol-Induced Airflow Limitation in Acetaldehyde Dehydrogenase 2-Deficient Mice.
Topics: Alcohol Drinking; Aldehyde Dehydrogenase, Mitochondrial; Animals; Asthma; Biomarkers; Disease Models | 2016 |
Dimerized Translationally Controlled Tumor Protein-Binding Peptide Ameliorates Atopic Dermatitis in NC/Nga Mice.
Topics: Animals; Biomarkers, Tumor; Cytokines; Dermatitis, Atopic; Disease Models, Animal; Female; Histamine | 2017 |
Immediate-type allergic and protease-mediated reactions are involved in scratching behaviour induced by topical application of Dermatophagoides farinae extract in NC/Nga mice.
Topics: Animals; Antibodies; Antipruritics; Behavior, Animal; Capillary Permeability; Chlorpheniramine; Comp | 2018 |
Demonstration of Biological and Immunological Equivalence of a Generic Glatiramer Acetate.
Topics: Animals; Antigen-Presenting Cells; B-Lymphocytes; Cytokines; Disease Models, Animal; Encephalomyelit | 2017 |
Heterogeneity of mast cells and expression of Annexin A1 protein in a second degree burn model with silver sulfadiazine treatment.
Topics: Animals; Annexin A1; Burns; Cell Count; Cell Proliferation; Cytokines; Cytoplasm; Dermis; Disease Mo | 2017 |
A novel zebrafish-based model of nociception.
Topics: Acetic Acid; Acrolein; Analgesics, Opioid; Animals; Antineoplastic Agents, Phytogenic; Disease Model | 2017 |
Effect of quercetin, flavonoids and alpha-tocopherol, an antioxidant vitamin, on experimental reflux oesophagitis in rats.
Topics: alpha-Tocopherol; Animals; Antioxidants; Catalase; Collagen; Disease Models, Animal; Esophagitis, Pe | 2008 |
Substance P is involved in the effect of histamine H3 receptor agonist, Sch 50971 on nasal allergic symptoms in mice.
Topics: Animals; Capsaicin; Cetirizine; Disease Models, Animal; Female; Histamine; Histamine Agonists; Hista | 2008 |
Quercetin inhalation inhibits the asthmatic responses by exposure to aerosolized-ovalbumin in conscious guinea-pigs.
Topics: Administration, Inhalation; Administration, Oral; Aerosols; Airway Resistance; Albuterol; Animals; A | 2008 |
Effects of inhaled monoethanolamine on bronchoconstriction.
Topics: Aerosols; Air Pollutants, Occupational; Airway Obstruction; Airway Resistance; Animals; Asthma; Atro | 2009 |
Brain-derived neurotrophic factor enhances histamine-induced airway responses and changes levels of exhaled nitric oxide in guinea pigs in vivo.
Topics: Administration, Inhalation; Animals; Brain-Derived Neurotrophic Factor; Bronchial Hyperreactivity; B | 2008 |
Induction of late airway response was involved in serum antigen-specific immunoglobulin G in rats.
Topics: Administration, Inhalation; Animals; Antigens; Asthma; Bronchoalveolar Lavage Fluid; Bronchoconstric | 2008 |
Chronic myocardial infarction induces phenotypic and functional remodeling in the guinea pig cardiac plexus.
Topics: Action Potentials; Animals; Autonomic Nervous System; Chronic Disease; Disease Models, Animal; Evoke | 2008 |
Modification of the picryl chloride-induced allergic dermatitis model in mouse ear lobes by 12-O-tetradecanoylphorbol 13-acetate, and analysis of the role of histamine in the modified model.
Topics: Animals; Cell Count; Cimetidine; Cyclophosphamide; Cyclosporine; Cytokines; Dermatitis, Allergic Con | 2009 |
Sho-seiryu-to suppresses histamine signaling at the transcriptional level in TDI-sensitized nasal allergy model rats.
Topics: Animals; Cytokines; Disease Models, Animal; Drugs, Chinese Herbal; Histamine; Histidine Decarboxylas | 2009 |
Food Allergy Herbal Formula-2 silences peanut-induced anaphylaxis for a prolonged posttreatment period via IFN-gamma-producing CD8+ T cells.
Topics: Allergens; Anaphylaxis; Animals; Arachis; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cy | 2009 |
Piperine inhibits eosinophil infiltration and airway hyperresponsiveness by suppressing T cell activity and Th2 cytokine production in the ovalbumin-induced asthma model.
Topics: Alkaloids; Animals; Asthma; Benzodioxoles; Bronchial Hyperreactivity; Cytokines; Disease Models, Ani | 2009 |
The role of histamine 3 receptors in the control of food intake in a seasonal model of obesity: the Siberian hamster.
Topics: Animals; Body Temperature; Cell Line, Transformed; Cricetinae; Disease Models, Animal; Eating; Hista | 2009 |
Histaminergic activity in a rodent model of Parkinson's disease.
Topics: Adrenergic Agents; Animals; Animals, Newborn; Apomorphine; Brain; Disease Models, Animal; Dopamine; | 2009 |
Concurrent blockade of platelet-activating factor and histamine prevents life-threatening peanut-induced anaphylactic reactions.
Topics: Allergens; Anaphylaxis; Animals; Arachis; Cholera Toxin; Cimetidine; Disease Models, Animal; Drug Th | 2009 |
The effect of wasabi rhizome extract on atopic dermatitis-like symptoms in HR-1 hairless mice.
Topics: Animals; Antibodies; Behavior, Animal; Brassicaceae; Chemokine CCL17; Chemokines, CC; Dermatitis, At | 2009 |
Somatostatin modulates mast cell-induced responses in murine spinal neurons and satellite cells.
Topics: Animals; Calcitonin Gene-Related Peptide; Calcium Signaling; Cells, Cultured; Disease Models, Animal | 2009 |
Anti-allergic effects of scoparone on mast cell-mediated allergy model.
Topics: Animals; Anti-Allergic Agents; Calcium; Coumarins; Cytokines; Disease Models, Animal; Dose-Response | 2009 |
Remodeling of the guinea pig intrinsic cardiac plexus with chronic pressure overload.
Topics: Action Potentials; Animals; Aorta, Thoracic; Cardiomegaly; Chronic Disease; Constriction; Disease Mo | 2009 |
Hypothalamic neuronal histamine signaling in the estrogen deficiency-induced obesity.
Topics: Analysis of Variance; Animals; Body Weight; Corticotropin-Releasing Hormone; Disease Models, Animal; | 2009 |
Expression of histamine H4 receptor in human epidermal tissues and attenuation of experimental pruritus using H4 receptor antagonist.
Topics: Animals; Disease Models, Animal; Epidermis; Histamine; Histamine Antagonists; Humans; Indoles; Kerat | 2009 |
A novel method for modeling facial allodynia associated with migraine in awake and freely moving rats.
Topics: Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Blood-Brain Barrier; Bradykinin; C | 2010 |
Acute gastric lesions induced by the administration of histamine to rats with partial vascular occlusion: evidence for the gastroprotective effect of prostaglandin.
Topics: Animals; Anti-Ulcer Agents; Dinoprostone; Disease Models, Animal; Histamine; Ischemia; Ligation; Mal | 2010 |
[Allergic response to qingkailing injection in BN rats].
Topics: Animals; Disease Models, Animal; Drugs, Chinese Herbal; Guinea Pigs; Histamine; Hypersensitivity, Im | 2009 |
Lung endothelial dysfunction in congestive heart failure: role of impaired Ca2+ signaling and cytoskeletal reorganization.
Topics: Acetylcholine; Actins; Animals; Blood Pressure; Calcium Signaling; Cholinergic Antagonists; Cytochal | 2010 |
Effect of German chamomile oil application on alleviating atopic dermatitis-like immune alterations in mice.
Topics: Animals; Behavior, Animal; Chamomile; Dermatitis, Atopic; Disease Models, Animal; Histamine; Immunog | 2010 |
Histamine H1 receptor promotes atherosclerotic lesion formation by increasing vascular permeability for low-density lipoproteins.
Topics: Animals; Aortic Diseases; Aortitis; Apolipoproteins E; Atherosclerosis; Bone Marrow Transplantation; | 2010 |
Glutathione prevents the early asthmatic reaction and airway hyperresponsiveness in guinea pigs.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Disease Models, Animal; Glutathione; Guinea Pigs; Histam | 2010 |
Inbred Chinese Wuzhishan (WZS) minipig model for soybean glycinin and beta-conglycinin allergy.
Topics: Animals; Antigens, Plant; Cytokines; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Food | 2010 |
Bepotastine besilate, a highly selective histamine H(1) receptor antagonist, suppresses vascular hyperpermeability and eosinophil recruitment in in vitro and in vivo experimental allergic conjunctivitis models.
Topics: Animals; Capillary Permeability; Cells, Cultured; Chemotaxis, Leukocyte; Conjunctiva; Conjunctivitis | 2010 |
Repeated histamine pretreatment decreased amnesia induced by post-training administration of the drug in a step-down inhibitory avoidance test in mice.
Topics: Amnesia; Analysis of Variance; Animals; Avoidance Learning; Behavior, Animal; Benzazepines; Disease | 2010 |
Anti-inflammatory effect of enzymatic hydrolysate of corn gluten in an experimental model of colitis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Colon, Descending; Dietary Supplements; D | 2010 |
Histamine and histamine receptors in pathogenesis and treatment of multiple sclerosis.
Topics: Animals; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Histamine; Histamine A | 2010 |
Antiinflammatory and antinociceptive activities of Zingiber zerumbet methanol extract in experimental model systems.
Topics: Analgesics; Analysis of Variance; Animals; Anti-Inflammatory Agents; Bradykinin; Carrageenan; Diseas | 2010 |
Pimecrolimus induces apoptosis of mast cells in a murine model of cutaneous mastocytosis.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cell Count; Di | 2010 |
Anti-allergic effects of total bakkenolides from Petasites tricholobus in ovalbumin-sensitized rats.
Topics: Animals; Anti-Allergic Agents; Disease Models, Animal; Histamine; Immunoglobulin E; Interleukin-4; M | 2011 |
[Acupoint-injection of histamine induced analgesic effect in acute adjuvant-induced-arthritis rats].
Topics: Acupuncture Points; Acute Disease; Analgesics; Animals; Arthritis; Disease Models, Animal; Freund's | 2010 |
Enhanced scratching evoked by PAR-2 agonist and 5-HT but not histamine in a mouse model of chronic dry skin itch.
Topics: Animals; Antibodies; Behavior, Animal; Calcium; Capsaicin; Disease Models, Animal; Ganglia, Spinal; | 2010 |
[Protective effect of "neiguan" (PC 6)-electroacupuncture preconditioning on the myocardium in myocardial ischemia/reperfusion rats].
Topics: Acupuncture Points; Animals; Disease Models, Animal; Electroacupuncture; Histamine; Humans; Male; Ma | 2010 |
A histamine H₂ receptor blocker ameliorates development of heart failure in dogs independently of β-adrenergic receptor blockade.
Topics: Adrenergic beta-Antagonists; Animals; Carbazoles; Cardiac Catheterization; Cardiac Pacing, Artificia | 2010 |
A novel strategy for development of glucocorticoids through non-genomic mechanism.
Topics: Animals; Cell Line; Disease Models, Animal; Genome; Glucocorticoids; Guinea Pigs; Histamine; Humans; | 2011 |
Enhancement of immediate allergic reactions by trichloroethylene ingestion via drinking water in mice.
Topics: Anaphylaxis; Animals; Body Weight; Cell Proliferation; Cytokines; Disease Models, Animal; Drinking; | 2010 |
Suppression of ovalbumin-induced Th2-driven airway inflammation by β-sitosterol in a guinea pig model of asthma.
Topics: Acetylcholine; Animals; Anti-Asthmatic Agents; Asthma; Body Weight; Bronchial Spasm; Bronchoalveolar | 2011 |
Inhibitory effects of Cinnamomum cassia extract on atopic dermatitis-like skin lesions induced by mite antigen in NC/Nga mice.
Topics: Allergens; Animals; Antigens, Dermatophagoides; Base Sequence; Cell Line; Chemokines; Cinnamomum aro | 2011 |
Differential itch- and pain-related behavioral responses and µ-opoid modulation in mice.
Topics: Analgesics, Opioid; Animals; Antigens, Plant; Behavior, Animal; Capsaicin; Disease Models, Animal; D | 2010 |
A role for the Ca2+ channel TRPML1 in gastric acid secretion, based on analysis of knockout mice.
Topics: Achlorhydria; Animals; Calcium; Disease Models, Animal; Gastric Acid; Gastrins; H(+)-K(+)-Exchanging | 2011 |
Intratracheal sensitization/challenge-induced biphasic asthmatic response and airway hyperresponsiveness in guinea pigs.
Topics: Airway Resistance; Animals; Anti-Asthmatic Agents; Antigens; Asthma; Bronchial Hyperreactivity; Chro | 2010 |
Gene transfer to muscle from the isolated regional circulation.
Topics: Animals; Blood Pressure; Capillaries; Capillary Permeability; Dependovirus; Disease Models, Animal; | 2011 |
Mesenteric lymph node transcriptome profiles in BALB/c mice sensitized to three common food allergens.
Topics: Allergens; Animals; Disease Models, Animal; Food Hypersensitivity; Gene Expression Profiling; Histam | 2011 |
Histamine restricts cancer: nothing to sneeze at.
Topics: Animals; Cell Survival; Colonic Neoplasms; Disease Models, Animal; Genes, Reporter; Histamine; Histi | 2011 |
A rat model of exercise-induced asthma: a nonspecific response to a specific immunogen.
Topics: Animals; Asthma; Bronchoconstriction; Cytokines; Disease Models, Animal; Histamine; Immunoglobulin E | 2011 |
Effect of Perilla frutescens var. acuta Kudo and rosmarinic acid on allergic inflammatory reactions.
Topics: Animals; Blotting, Western; Cell Line; Cinnamates; Conjunctivitis, Allergic; Cyclooxygenase 2; Cytok | 2011 |
Histamine deficiency decreases atherosclerosis and inflammatory response in apolipoprotein E knockout mice independently of serum cholesterol level.
Topics: Animals; Aortic Diseases; Apolipoproteins E; Atherosclerosis; Blotting, Western; Cholesterol; Choles | 2011 |
Increased susceptibility of 129SvEvBrd mice to IgE-Mast cell mediated anaphylaxis.
Topics: Anaphylaxis; Animals; Apoptosis; Body Temperature; Cell Degranulation; Cell Proliferation; Cells, Cu | 2011 |
Suppression of mast-cell-mediated allergic inflammation by Lindera obtusiloba.
Topics: Animals; Anti-Allergic Agents; Calcium; Cell Line; Disease Models, Animal; Gene Expression; Histamin | 2011 |
Enhanced responses of lumbar superficial dorsal horn neurons to intradermal PAR-2 agonist but not histamine in a mouse hindpaw dry skin itch model.
Topics: Acetone; Action Potentials; Analysis of Variance; Animals; Antipruritics; Capsaicin; Disease Models, | 2011 |
TRPA1 is required for histamine-independent, Mas-related G protein-coupled receptor-mediated itch.
Topics: Analysis of Variance; Animals; Animals, Newborn; Antirheumatic Agents; Calcium; Capsaicin; Cells, Cu | 2011 |
In vivo MR imaging of plaque disruption and thrombus formation in an atherosclerotic rabbit model.
Topics: Animals; Aorta, Abdominal; Aortic Diseases; Atherosclerosis; Catheterization; Cholesterol, Dietary; | 2012 |
Prophylactic effects of the histamine H1 receptor antagonist epinastine and the dual thromboxane A2 receptor and chemoattractant receptor-homologous molecule expressed on Th2 cells antagonist ramatroban on allergic rhinitis model in mice.
Topics: Animals; Anti-Allergic Agents; Behavior, Animal; Benzoquinones; Carbazoles; Dibenzazepines; Disease | 2011 |
Sex differences in behavior and expression of CGRP-related genes in a rodent model of chronic migraine.
Topics: Animals; Behavior, Animal; Bradykinin; Calcitonin Gene-Related Peptide; Chronic Disease; Dinoproston | 2011 |
Lack of preventing effect of systemically and topically administered histamine H(1) or H(4) receptor antagonists in a dog model of acute atopic dermatitis.
Topics: Aging; Animals; Antigens, Dermatophagoides; Cetirizine; Dermatitis, Atopic; Dermatophagoides farinae | 2011 |
Role of TRPV1 in nociception and edema induced by monosodium urate crystals in rats.
Topics: Acrylamides; Anilides; Animals; Anti-Allergic Agents; Anti-Asthmatic Agents; Antioxidants; Bridged B | 2011 |
Kanamycin activates caspase-1 in NC/Nga mice.
Topics: Animals; Anti-Bacterial Agents; Caspase 1; Dermatitis, Atopic; Disease Models, Animal; Histamine; I- | 2011 |
Antisecretory actions of Baccharis trimera (Less.) DC aqueous extract and isolated compounds: analysis of underlying mechanisms.
Topics: Aminopyrine; Animals; Antacids; Baccharis; Chlorogenic Acid; Cyclohexanecarboxylic Acids; Disease Mo | 2011 |
Transcriptional microarray analysis reveals suppression of histamine signaling by Kujin alleviates allergic symptoms through down-regulation of FAT10 expression.
Topics: Animals; Disease Models, Animal; Down-Regulation; Histamine; Histamine H1 Antagonists; Humans; Hyper | 2011 |
Interaction between histamine and morphine at the level of the hippocampus in the formalin-induced orofacial pain in rats.
Topics: Analgesics, Opioid; Animals; Disease Models, Animal; Facial Pain; Formaldehyde; Hippocampus; Histami | 2011 |
Ameliorative effect of thymoquinone on ovalbumin-induced allergic conjunctivitis in Balb/c mice.
Topics: Animals; Benzoquinones; Chromatography, High Pressure Liquid; Conjunctivitis, Allergic; Cytokines; D | 2011 |
Role of hematopoietic prostaglandin D synthase in biphasic nasal obstruction in guinea pig model of experimental allergic rhinitis.
Topics: Animals; Benzimidazoles; Dinoprostone; Disease Models, Animal; Eosinophils; Guinea Pigs; Histamine; | 2011 |
Systemic mast cell degranulation increases mortality during polymicrobial septic peritonitis in mice.
Topics: Animals; Cecum; Cell Degranulation; Cells, Cultured; Disease Models, Animal; Histamine; Interleukin- | 2011 |
Sex differences in the inflammatory mediator-induced sensitization of dural afferents.
Topics: Action Potentials; Afferent Pathways; Animals; Blood Vessels; Bradykinin; Dinoprostone; Disease Mode | 2011 |
Suppression of dust mite extract and 2,4-dinitrochlorobenzene-induced atopic dermatitis by the water extract of Lindera obtusiloba.
Topics: Administration, Cutaneous; Animals; Anti-Allergic Agents; Antigens, Dermatophagoides; Dermatitis, At | 2011 |
Comparison of metabolites in exhaled breath and bronchoalveolar lavage fluid samples in a mouse model of asthma.
Topics: Animals; Arachidonic Acid; Asthma; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Exhalation; | 2011 |
Albizia lebbeck suppresses histamine signaling by the inhibition of histamine H1 receptor and histidine decarboxylase gene transcriptions.
Topics: Albizzia; Animals; Disease Models, Animal; HeLa Cells; Histamine; Histamine H1 Antagonists; Histidin | 2011 |
Effect of pre- and postnatal manganese exposure on brain histamine content in a rodent model of Parkinson's disease.
Topics: Animals; Animals, Newborn; Brain; Disease Models, Animal; Dopamine; Drinking Water; Female; Histamin | 2012 |
Cortex Mori Radicis extract exerts antiasthmatic effects via enhancement of CD4(+)CD25(+)Foxp3(+) regulatory T cells and inhibition of Th2 cytokines in a mouse asthma model.
Topics: Allergens; Animals; Anti-Asthmatic Agents; Asthma; Cytokines; Disease Models, Animal; Drugs, Chinese | 2011 |
Inducible nitric oxide synthase (iNOS) and α-melanocyte-stimulating hormones of iNOS origin play important roles in the allergic reactions of atopic dermatitis in mice.
Topics: Adrenocorticotropic Hormone; alpha-MSH; Animals; Dermatitis, Atopic; Disease Models, Animal; Enzyme | 2011 |
TLR-induced activation of neutrophils promotes histamine production via a PI3 kinase dependent mechanism.
Topics: Administration, Inhalation; Animals; Basophils; Disease Models, Animal; Granulocyte-Macrophage Colon | 2011 |
Involvement of mast cells in a mouse model of postoperative pain.
Topics: Animals; Cell Degranulation; Disease Models, Animal; Histamine; Histamine H1 Antagonists; Male; Mast | 2011 |
[Experimental model of histamine-induced anaphylactoid reaction on beagle dogs].
Topics: Anaphylaxis; Animals; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Drugs, Chinese | 2011 |
Vimentin and laminin are altered on cheek pouch microvessels of streptozotocin-induced diabetic hamsters.
Topics: Acetylcholine; Animals; Arterioles; Cell Membrane Permeability; Cheek; Cricetinae; Diabetes Mellitus | 2011 |
Immunomodulatory effects of heated ovomucoid-depleted egg white in a BALB/c mouse model of egg allergy.
Topics: Administration, Oral; Animals; Cells, Cultured; Cytokines; Digestion; Disease Models, Animal; Egg Hy | 2011 |
Anti-edematous effects of tolvaptan in experimental rodent models.
Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Benzazepines; Carrageenan; Disease Models, Anima | 2011 |
Ovalicin ameliorates compound 48/80-induced atopic dermatitis-related symptoms.
Topics: Animals; Anti-Allergic Agents; Behavior, Animal; Dermatitis, Atopic; Disease Models, Animal; Histami | 2011 |
The central histamine level in rat model of vascular dementia.
Topics: Acetylcholinesterase; Animals; Brain; Carotid Stenosis; Cholinesterase Inhibitors; Dementia, Vascula | 2011 |
Prostaglandin E1 dose-dependently promotes stability of atherosclerotic plaque in a rabbit model.
Topics: Alprostadil; Angioplasty, Balloon; Animals; Anti-Inflammatory Agents; Aorta, Abdominal; Aortic Disea | 2012 |
Red ginseng inhibits scratching behavior associated with atopic dermatitis in experimental animal models.
Topics: Administration, Topical; Animals; Anti-Allergic Agents; Behavior, Animal; Capillary Permeability; De | 2012 |
Mouse model of touch-evoked itch (alloknesis).
Topics: Animals; Disease Models, Animal; Histamine; Mice; Mice, Inbred C57BL; Naltrexone; Oligopeptides; Pep | 2012 |
In vivo evidence of cross-reactivity between cow's milk and soybean proteins in a mouse model of food allergy.
Topics: Animals; Cross Reactions; Cytokines; Disease Models, Animal; Food Hypersensitivity; Histamine; Immun | 2012 |
Involvement of leukotriene B4 in itching in a mouse model of ocular allergy.
Topics: Allergens; Ambrosia; Animals; Conjunctivitis, Allergic; Disease Models, Animal; Glucocorticoids; His | 2012 |
Histamine- and haloperidol-induced catalepsy in aged mice: differential responsiveness to L-DOPA.
Topics: Aging; Animals; Antiparkinson Agents; Catalepsy; Disease Models, Animal; Dopamine; Dose-Response Rel | 2012 |
A shorter and more specific oral sensitization-based experimental model of food allergy in mice.
Topics: Administration, Oral; Animals; Cattle; Cholera Toxin; Diarrhea; Disease Models, Animal; Enzyme-Linke | 2012 |
Antipyretic, analgesic and anti-inflammatory activity of Viola betonicifolia whole plant.
Topics: Acetaminophen; Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Antipyretics; Behavior, A | 2012 |
Bronchoprotection in conscious guinea pigs by budesonide and the NO-donating analogue, TPI 1020, alone and combined with tiotropium or formoterol.
Topics: Administration, Inhalation; Animals; Bronchoconstriction; Bronchodilator Agents; Budesonide; Disease | 2012 |
Lipopolysaccharide enhances FcεRI-mediated mast cell degranulation by increasing Ca2+ entry through store-operated Ca2+ channels: implications for lipopolysaccharide exacerbating allergic asthma.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Calcium Channel Blockers; | 2012 |
The antagonism of histamine H1 and H4 receptors ameliorates chronic allergic dermatitis via anti-pruritic and anti-inflammatory effects in NC/Nga mice.
Topics: Animals; Anti-Allergic Agents; Anti-Inflammatory Agents; Bone Marrow Cells; Chemokine CCL17; Chemoki | 2012 |
Experimental model of allergic asthma.
Topics: Airway Resistance; Animals; Asthma; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Citric Acid; | 2013 |
Protective effect of carnosine on subcortical ischemic vascular dementia in mice.
Topics: Animals; Avoidance Learning; Carnosine; Corpus Callosum; Dementia, Vascular; Disease Models, Animal; | 2012 |
Preconditioning of the response to ischemia/ reperfusion-induced plasma leakage in hamster cheek pouch microcirculation.
Topics: Animals; Bradykinin; Capillary Permeability; Cheek; Cricetinae; Disease Models, Animal; Histamine; H | 2012 |
The effect of unilateral adrenalectomy on transformation of adrenal medullary chromaffin cells in vivo: a potential mechanism of asthma pathogenesis.
Topics: Adrenal Medulla; Adrenalectomy; Animals; Asthma; Bronchoconstriction; Chromaffin Cells; Corticostero | 2012 |
Prophylaxis of intranasally induced pollen allergy in a BALB/C mouse model using a potential prebiotic β-1, 4 mannobiose.
Topics: Allergens; Animals; Antibody Specificity; Antigens, Plant; Chymases; Cytokines; Disease Models, Anim | 2013 |
A comparison of antiasthma drugs between acute and chronic ovalbumin-challenged guinea-pig models of asthma.
Topics: Acute Disease; Administration, Inhalation; Administration, Oral; Aminopyridines; Androstadienes; Ani | 2012 |
Hemodynamic and catecholamine changes after recurrent ventricular fibrillation.
Topics: Animals; Blood Pressure; Catecholamines; Creatine Kinase, MB Form; Disease Models, Animal; Female; H | 2013 |
Therapeutic effects of β1, 4 mannobiose in a Balb/c mouse model of intranasally-induced pollen allergy.
Topics: Allergens; Animals; Cell Line; Cytokines; Disease Models, Animal; Female; Gene Expression; Histamine | 2013 |
Pravastatin inhibits plaque rupture and subsequent thrombus formation in atherosclerotic rabbits with hyperlipidemia.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anticholesteremic Agents; Aorta; Aorta, Abdominal; Atheroscle | 2013 |
Interaction of SSR161421, a novel specific adenosine A(3) receptor antagonist with adenosine A(3) receptor agonists both in vitro and in vivo.
Topics: Adenosine; Adenosine A3 Receptor Agonists; Adenosine A3 Receptor Antagonists; Aminoquinolines; Anima | 2013 |
[Effects of Wuling mycelia on pentylenetetrazole-induced epilepsy in rats].
Topics: Animals; Disease Models, Animal; Drugs, Chinese Herbal; Epilepsy; Hippocampus; Histamine; Kindling, | 2012 |
Escin inhibits type I allergic dermatitis in a novel porcine model.
Topics: Animals; Anti-Allergic Agents; Dermatitis, Atopic; Disease Models, Animal; Dose-Response Relationshi | 2013 |
Lansiumamide B and SB-204900 isolated from Clausena lansium inhibit histamine and TNF-α release from RBL-2H3 cells.
Topics: Animals; Calcimycin; Calcium Ionophores; Cell Line; Cell Survival; Cinnamates; Clausena; Cyclooxygen | 2013 |
Quercetin inhibits transcriptional up-regulation of histamine H1 receptor via suppressing protein kinase C-δ/extracellular signal-regulated kinase/poly(ADP-ribose) polymerase-1 signaling pathway in HeLa cells.
Topics: Animals; Cytosol; Dermatitis, Contact; Disease Models, Animal; Golgi Apparatus; HeLa Cells; Histamin | 2013 |
H. pylori acutely inhibits gastric secretion by activating CGRP sensory neurons coupled to stimulation of somatostatin and inhibition of histamine secretion.
Topics: Achlorhydria; Animals; Calcitonin Gene-Related Peptide; Disease Models, Animal; Gastric Acid; Gastri | 2013 |
Anti-inflammatory and antinociceptive properties of dantrolene sodium in rats and mice.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Dantrolene; | 2002 |
Accelerated clearance of Escherichia coli in experimental peritonitis of histamine-deficient mice.
Topics: Animals; Disease Models, Animal; Escherichia coli; Escherichia coli Infections; Histamine; Histamine | 2002 |
Production of acute and chronic itch with histamine and contact sensitizers in the mouse and guinea pig.
Topics: Acute Disease; Animals; Capsaicin; Chronic Disease; Dinitrochlorobenzene; Disease Models, Animal; Fe | 2002 |
Role of acid back-diffusion, glutathione, oxyradical, and histamine in antral hemorrhagic ulcer in rats: the protective effect of lysozyme chloride and antioxidants.
Topics: Animals; Antioxidants; Diffusion; Disease Models, Animal; Dose-Response Relationship, Drug; Gastric | 2002 |
Fasting stress exacerbates classical conditioned histamine release in guinea pigs.
Topics: Animals; Asthma; Bronchoconstriction; Conditioning, Classical; Disease Models, Animal; Food Deprivat | 2002 |
Thrombosis increases circulatory hepatocyte growth factor by degranulation of mast cells.
Topics: Animals; Anticoagulants; Arginine; Carotid Artery Thrombosis; Cell Degranulation; Disease Models, An | 2002 |
Disruption of L-histidine decarboxylase reduces airway eosinophilia but not hyperresponsiveness.
Topics: Administration, Inhalation; Airway Resistance; Animals; Asthma; Bone Marrow Cells; Bronchial Hyperre | 2003 |
Canine model of nasal congestion and allergic rhinitis.
Topics: Aerosols; Airway Resistance; Ambrosia; Animals; Disease Models, Animal; Dogs; Female; Heart Rate; Hi | 2003 |
Engineered recombinant peanut protein and heat-killed Listeria monocytogenes coadministration protects against peanut-induced anaphylaxis in a murine model.
Topics: 2S Albumins, Plant; Adjuvants, Immunologic; Allergens; Anaphylaxis; Animals; Antigens, Plant; Arachi | 2003 |
Modulation of the Th1/Th2 bias by an immunoglobulin histamine complex in the ovalbumin allergy mouse model.
Topics: Animals; Anti-Allergic Agents; Disease Models, Animal; Drug Combinations; Female; gamma-Globulins; H | 2003 |
Thymoquinone protects against experimental colitis in rats.
Topics: Acetic Acid; Animals; Benzoquinones; Colitis; Colon; Disease Models, Animal; Dose-Response Relations | 2003 |
Distinct narcolepsy syndromes in Orexin receptor-2 and Orexin null mice: molecular genetic dissection of Non-REM and REM sleep regulatory processes.
Topics: Animals; Arousal; Carrier Proteins; Cells, Cultured; Clomipramine; Disease Models, Animal; Efferent | 2003 |
Luminal salmonella endotoxin affects epithelial and mast cell function in the proximal colon of pigs.
Topics: Acute-Phase Reaction; Animals; Bacterial Toxins; Bacterial Translocation; C-Reactive Protein; Colon; | 2003 |
Histamine dihydrochloride and cancer.
Topics: Animals; Clinical Trials as Topic; Disease Models, Animal; Histamine; Humans; Immunotherapy; Killer | 2003 |
Contractions to histamine in pulmonary and mesenteric arteries from endotoxemic rabbits: modulation by vascular expressions of inducible nitric-oxide synthase and histamine H1-receptors.
Topics: Animals; Disease Models, Animal; Endotoxemia; Gene Expression; Histamine; Histidine Decarboxylase; M | 2003 |
Effects of TAK-427 on acute nasal symptoms and nasal obstruction in guinea pig model of experimental allergic rhinitis.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Disease Models, Animal; Guinea Pigs; Histamine; Hi | 2003 |
Pulmonary inflammation and thrombogenicity caused by diesel particles in hamsters: role of histamine.
Topics: Animals; Bronchoalveolar Lavage Fluid; Cricetinae; Diphenhydramine; Disease Models, Animal; Histamin | 2003 |
Influence of histamine in a liver injury model induced by Propionibacterium acnes and lipopolysaccharide.
Topics: Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Drug | 2003 |
Acute stress modulates the histamine content of mast cells in the gastrointestinal tract through interleukin-1 and corticotropin-releasing factor release in rats.
Topics: Adrenocorticotropic Hormone; Animals; Colon; Corticotropin-Releasing Hormone; Cortisone; Digestive S | 2003 |
Role of sensory nerve peptides rather than mast cell histamine in paclitaxel hypersensitivity.
Topics: Analysis of Variance; Animals; Biopsy, Needle; Bronchoalveolar Lavage Fluid; Calcitonin Gene-Related | 2004 |
Tumor necrosis factors in a murine model of allergic peritonitis: effects on eosinophil accumulation and inflammatory mediators' release.
Topics: Animals; Disease Models, Animal; Eosinophil Peroxidase; Eosinophils; Histamine; Hypersensitivity; In | 2003 |
Hypothalamic neuronal histamine in genetically obese animals: its implication of leptin action in the brain.
Topics: alpha-MSH; Animals; Corticotropin-Releasing Hormone; Disease Models, Animal; Histamine; Hypothalamus | 2003 |
Parental allergic status influences the risk of developing allergic sensitization and an asthmatic-like phenotype in canine offspring.
Topics: Administration, Inhalation; Airway Resistance; Allergens; Ambrosia; Animals; Antibody Formation; Ast | 2003 |
Facilitating effect of histamine on spatial memory deficits induced by dizocilpine as evaluated by 8-arm radial maze in SD rats.
Topics: Animals; Disease Models, Animal; Dizocilpine Maleate; Histamine; Histidine; Injections, Intraventric | 2003 |
Dust mite-induced asthma in cynomolgus monkeys.
Topics: Adenosine; Aerosols; Allergens; Animals; Asthma; Bronchial Provocation Tests; Cytokines; Disease Mod | 2004 |
Effects of nonsteroidal anti-inflammatory drugs on experimental allergic conjunctivitis in Guinea pigs.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antigens; Benzophenones; | 2003 |
Role of histamine and acid back-diffusion in modulation of gastric microvascular permeability and hemorrhagic ulcers in Salmonella typhimurium-infected rats.
Topics: Amine Oxidase (Copper-Containing); Animals; Capillary Permeability; Diphenhydramine; Disease Models, | 2004 |
A chronic model for evaluating the itching associated with allergic conjunctivitis in rats.
Topics: Animals; Anti-Allergic Agents; Antigens; Chronic Disease; Conjunctivitis, Allergic; Disease Models, | 2004 |
The role of central mu opioid receptors in opioid-induced itch in primates.
Topics: Analgesics, Opioid; Animals; Disease Models, Animal; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Histamine; | 2004 |
Involvement of the renin-angiotensin system in endogenous central histamine-induced reversal of critical haemorrhagic hypotension in rats.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Blood Pressure; Brain Chemistry; C | 2004 |
Involvement of proopiomenalocortin-derived peptides in endogenous central histamine-induced reversal of critical haemorrhagic hypotension in rats.
Topics: Adrenocorticotropic Hormone; alpha-MSH; Animals; Brain Chemistry; Disease Models, Animal; Heart Rate | 2004 |
Cataplexy-active neurons in the hypothalamus: implications for the role of histamine in sleep and waking behavior.
Topics: Action Potentials; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Cataplexy; Dise | 2004 |
Cough reflex in allergic dogs.
Topics: Aerosols; Animals; Bronchial Provocation Tests; Cough; Disease Models, Animal; Dogs; Histamine; Hype | 2004 |
Hydroxyzine from topical phospholipid liposomal formulations: evaluation of peripheral antihistaminic activity and systemic absorption in a rabbit model.
Topics: Animals; Chemistry, Pharmaceutical; Disease Models, Animal; Drug Delivery Systems; Histamine; Histam | 2003 |
Protective effect of melatonin on experimental otitis media with effusion in guinea pigs.
Topics: Animals; Antioxidants; Disease Models, Animal; Erythrocytes; Guinea Pigs; Histamine; Lipid Peroxidat | 2004 |
Role of histaminergic neurons in development of epileptic seizures in EL mice.
Topics: Animals; Brain; Disease Models, Animal; Drug Therapy, Combination; Enzyme Inhibitors; Epilepsy; Epil | 2004 |
The effect of EGF application in gel form on histamine content of experimentally induced wound in mice.
Topics: Acrylic Resins; Administration, Topical; Animals; Collagen; Disease Models, Animal; Epidermal Growth | 2004 |
Increased activity of the intestinal mucosal mast cells in rats with multiple organ failure.
Topics: Animals; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Fluorometry; Histamine; | 2004 |
Neuronal TGF-beta1 mediates IL-9/mast cell interaction and exacerbates excitotoxicity in newborn mice.
Topics: Animals; Animals, Newborn; Antibodies; Brain; Cell Line; Cerebral Palsy; Disease Models, Animal; Fem | 2005 |
Activation of Rho-associated kinase during augmented contraction of the basilar artery to serotonin after subarachnoid hemorrhage.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Basilar Artery; Disease Models, Animal; Enzy | 2005 |
Effects of Vitamin E on airway responses and biochemical parameters in guinea pigs sensitized to ovalbumin.
Topics: Adenosine Triphosphatases; Animals; Bronchial Hyperreactivity; Calcium; Diet Therapy; Disease Models | 2005 |
Airway closure after antigen challenge in cynomolgus monkeys: effect of the histamine H1 receptor antagonist, chlorpheniramine maleate.
Topics: Airway Obstruction; Animals; Ascaris suum; Blood Gas Analysis; Chlorpheniramine; Cross-Over Studies; | 2005 |
In vivo PAF-induced airway eosinophil accumulation reduces bronchial responsiveness to inhaled histamine.
Topics: Administration, Inhalation; Animals; Asthma; Bronchi; Bronchial Hyperreactivity; Bronchoalveolar Lav | 2005 |
[Assessment of the BALB/c mice as a suitable animal model for the investigation of food allergy].
Topics: Acid Phosphatase; Animals; Disease Models, Animal; Female; Food Hypersensitivity; Histamine; Immunog | 2005 |
[Neurohumoral changes in acute intestinal obstruction].
Topics: Acute Disease; Animals; Catecholamines; Disease Models, Animal; Histamine; Homeostasis; Humans; Inte | 2005 |
Liriopis tuber inhibit OVA-induced airway inflammation and bronchial hyperresponsiveness in murine model of asthma.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Cytokines; Disease Models, Animal; Eosinophils; Histamin | 2005 |
A novel A1 adenosine receptor antagonist, L-97-1 [3-[2-(4-aminophenyl)-ethyl]-8-benzyl-7-{2-ethyl-(2-hydroxy-ethyl)-amino]-ethyl}-1-propyl-3,7-dihydro-purine-2,6-dione], reduces allergic responses to house dust mite in an allergic rabbit model of asthma.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Anti-Asthmatic Agents; Asthma; Bronchial Hype | 2005 |
Deficits in cortico-striatal synaptic plasticity and behavioral habituation in rats with portacaval anastomosis.
Topics: Animals; Behavior, Animal; Cognition Disorders; Corpus Striatum; Disease Models, Animal; Electric St | 2005 |
Dietary unripe apple polyphenol inhibits the development of food allergies in murine models.
Topics: Allergens; Animals; Body Temperature; Body Weight; Disease Models, Animal; Female; Flavonoids; Food | 2005 |
Antipruritic effect of ginsenoside rb1 and compound k in scratching behavior mouse models.
Topics: Animals; Antipruritics; Behavior, Animal; Capillary Permeability; Disease Models, Animal; Ginsenosid | 2005 |
Experimental studies on artificial blood usage for hemodilution during cardiopulmonary bypass.
Topics: Analysis of Variance; Animals; Blood Substitutes; Bradykinin; Cardiopulmonary Bypass; Disease Models | 2005 |
TNF-alpha induces the late-phase airway hyperresponsiveness and airway inflammation through cytosolic phospholipase A(2) activation.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; | 2005 |
Nonatopic allergen-independent mast cell activation in parasitized eosinophilic athymic rats.
Topics: Animals; Antigens, Helminth; Ascariasis; Ascaris suum; Bronchoalveolar Lavage Fluid; Cell Degranulat | 2005 |
Effects of mometasone furoate on a rat allergic rhinitis model.
Topics: Administration, Intranasal; Animals; Anti-Allergic Agents; Antigens; Behavior, Animal; Chlorpheniram | 2005 |
Anisakis simplex allergy: a murine model of anaphylaxis induced by parasitic proteins displays a mixed Th1/Th2 pattern.
Topics: Allergens; Anaphylaxis; Animals; Anisakis; Antigens, Helminth; Cytokines; Disease Models, Animal; He | 2005 |
Effect of dantrolene on lipid peroxidation, lutathione and glutathione-dependent enzyme activities in experimental otitis media with effusion in guinea pigs.
Topics: Animals; Dantrolene; Disease Models, Animal; Erythrocytes; Glutathione; Glutathione Peroxidase; Glut | 2005 |
Hypertriglyceridemia but not hypercholesterolemia induces endothelial dysfunction in the rat.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Disease Models, Animal; Endothelium, Vascular; Epoprostenol | 2005 |
Long-lasting changes in small intestinal transport following the recovery from Trichinella spiralis infection.
Topics: Animals; Biological Transport; Carbachol; Cholinergic Agonists; Disease Models, Animal; Electric Sti | 2006 |
Positive interaction of the novel beta2-agonist carmoterol and tiotropium bromide in the control of airway changes induced by different challenges in guinea-pigs.
Topics: Acetylcholine; Adrenergic beta-2 Receptor Agonists; Airway Obstruction; Airway Resistance; Amphetami | 2007 |
Positive interaction of the novel beta2-agonist carmoterol and tiotropium bromide in the control of airway changes induced by different challenges in guinea-pigs.
Topics: Acetylcholine; Adrenergic beta-2 Receptor Agonists; Airway Obstruction; Airway Resistance; Amphetami | 2007 |
Positive interaction of the novel beta2-agonist carmoterol and tiotropium bromide in the control of airway changes induced by different challenges in guinea-pigs.
Topics: Acetylcholine; Adrenergic beta-2 Receptor Agonists; Airway Obstruction; Airway Resistance; Amphetami | 2007 |
Positive interaction of the novel beta2-agonist carmoterol and tiotropium bromide in the control of airway changes induced by different challenges in guinea-pigs.
Topics: Acetylcholine; Adrenergic beta-2 Receptor Agonists; Airway Obstruction; Airway Resistance; Amphetami | 2007 |
Nasal congestion model in Brown Norway rats and the effects of some H1-antagonists.
Topics: Animals; Chlorpheniramine; Dibenzazepines; Disease Models, Animal; Histamine; Histamine H1 Antagonis | 2006 |
The effects of diamine oxidase administration on experimental ulcerative colitis in rats.
Topics: Amine Oxidase (Copper-Containing); Animals; Colitis, Ulcerative; Disease Models, Animal; Histamine; | 2006 |
Characteristics of scratching behavior induced by some chemical mediators in hairless mice.
Topics: Animals; Antipruritics; Behavior, Animal; Dermatitis, Atopic; Disease Models, Animal; Dose-Response | 2006 |
The H1 histamine receptor regulates allergic lung responses.
Topics: Administration, Intranasal; Animals; Cell Movement; Cytokines; Disease Models, Animal; Histamine; In | 2006 |
The systems biology of infection in animal models bears fruit.
Topics: Animals; Disease Models, Animal; Histamine; Infections; Systems Biology | 2006 |
Effect of a Chinese herbal formula, Shi-Bi-Lin, on an experimental model of allergic rhinitis.
Topics: Animals; Anti-Allergic Agents; Disease Models, Animal; Drugs, Chinese Herbal; Eosinophils; Guinea Pi | 2006 |
Persistent inflammation and hyperresponsiveness following viral rhinosinusitis.
Topics: Animals; CD4 Antigens; CD8 Antigens; Disease Models, Animal; Flow Cytometry; Histamine; Hypersensiti | 2006 |
Spontaneous scratching behaviour in DS-Nh mice as a possible model for pruritus in atopic dermatitis.
Topics: Animals; Antipruritics; Cells, Cultured; Dermatitis, Atopic; Disease Models, Animal; Histamine; Hist | 2006 |
Antiinflammatory effects of Tacrolimus in a mouse model of pleurisy.
Topics: Adenosine Deaminase; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Bradykinin; Carrageen | 2006 |
Mechanism for acute oral desensitization to antibiotics.
Topics: Administration, Oral; Anaphylaxis; Animals; Anti-Bacterial Agents; Desensitization, Immunologic; Dis | 2006 |
Evidence of anti-inflammatory effects of Passiflora edulis in an inflammation model.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bradykinin; Carrageenan; Disease Models, Animal; F | 2007 |
Airway hyperresponsiveness induced by repetitive intraperitoneal injection of lipopolysacharide and the involvement of inflammation and nitric oxide in guinea pigs.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Calcium; Disease Models, Animal; Gene Expression Regu | 2006 |
Adenosine A1 receptor antagonist versus montelukast on airway reactivity and inflammation.
Topics: Acetates; Adenosine A1 Receptor Antagonists; Animals; Anti-Asthmatic Agents; Asthma; Bronchial Hyper | 2006 |
[Effect of nociceptin on histamine and serotonin release in the central nervous system].
Topics: Animals; Disease Models, Animal; Hippocampus; Histamine; Histamine Release; Hypothalamus; Pain; Rats | 2006 |
Synergistic antitumor effects of histamine plus melphalan in isolated hepatic perfusion for liver metastases.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Cancer, Regional Perfusion; D | 2007 |
Phospholipase Cbeta 3 mediates the scratching response activated by the histamine H1 receptor on C-fiber nociceptive neurons.
Topics: Animals; Calcium Signaling; Cells, Cultured; Disease Models, Animal; Female; Ganglia, Spinal; Histam | 2006 |
Transtympanic versus intramuscular steroid administration in a histamine-induced inflammatory middle-ear model.
Topics: Animals; Dexamethasone; Disease Models, Animal; Glucocorticoids; Histamine; Injections, Intramuscula | 2007 |
Histamine H4 receptor antagonists are superior to traditional antihistamines in the attenuation of experimental pruritus.
Topics: Animals; Disease Models, Animal; Edema; Female; Foot; Histamine; Histamine Agonists; Histamine Antag | 2007 |
In vitro and in vivo evaluation of the anti-asthmatic activities of fractions from Pheretima.
Topics: Animals; Anti-Asthmatic Agents; Antitussive Agents; Asthma; Cough; Disease Models, Animal; Dose-Resp | 2007 |
Contributions of histamine, prostanoids, and neurokinins to edema elicited by edema toxin from Bacillus anthracis.
Topics: Animals; Antigens, Bacterial; Aprepitant; Bacillus anthracis; Bacterial Toxins; Capillary Permeabili | 2007 |
Establishment of an allergic rhinitis model in mice for the evaluation of nasal symptoms.
Topics: Animals; Anti-Allergic Agents; Anti-Inflammatory Agents; Antigens; Cryptomeria; Dexamethasone; Disea | 2007 |
Fritillaria cirrhosa, Anemarrhena asphodeloides, Lee-Mo-Tang and cyclosporine a inhibit ovalbumin-induced eosinophil accumulation and Th2-mediated bronchial hyperresponsiveness in a murine model of asthma.
Topics: Anemarrhena; Animals; Anti-Asthmatic Agents; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lava | 2007 |
H3 histamine receptor agonist inhibits biliary growth of BDL rats by downregulation of the cAMP-dependent PKA/ERK1/2/ELK-1 pathway.
Topics: Animals; Bile Ducts; Bile Ducts, Intrahepatic; Cell Proliferation; Cyclic AMP; Cyclic AMP-Dependent | 2007 |
A dual antagonist for chemokine CCR3 receptor and histamine H1 receptor.
Topics: Animals; Anti-Allergic Agents; Anti-Inflammatory Agents; Asthma; Calcium Signaling; Capillary Permea | 2007 |
[Implication of 5-lipoxygenase/cysteinyl leukotriene receptors and histamine/histamine receptors in brain disease].
Topics: Animals; Arachidonate 5-Lipoxygenase; Brain Diseases; Disease Models, Animal; Histamine; Humans; Mem | 2007 |
[Experimental gastric and duodenal ulcer models: their potential and restrictions].
Topics: Acetylcholine; Animals; Disease Models, Animal; Duodenal Ulcer; Gastric Mucosa; Histamine; Microcirc | 2007 |
Histamine 4 receptor activation induces recruitment of FoxP3+ T cells and inhibits allergic asthma in a murine model.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; CD4 Antigens; Cell Movement; Cytokines; Disease Model | 2007 |
[Study of cellularity in bronchoalveolar fluid and bronchial reactivity to histamine in a model of asthma in guinea pig].
Topics: Allergens; Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Disease Models, | 2006 |
Implication of dipeptidylpeptidase IV activity in human bronchial inflammation and in bronchoconstriction evaluated in anesthetized rabbits.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Animals; Biomarkers; Bronchial Hyperreactivity | 2008 |
Anti-inflammatory evaluation of Solidago chilensis Meyen in a murine model of pleurisy.
Topics: Adenosine Deaminase; Animals; Anti-Inflammatory Agents; Bradykinin; Butanols; Carrageenan; Disease M | 2007 |
Protective effect of (+)-catechin against gastric mucosal injury induced by ischaemia-reperfusion in rats.
Topics: Administration, Oral; Alkaline Phosphatase; Animals; Antioxidants; Catalase; Catechin; Corticosteron | 2007 |
The COX-2 inhibitor SC-236 exerts anti-inflammatory effects by suppressing phosphorylation of ERK in a murine model.
Topics: Animals; Anti-Inflammatory Agents; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; | 2007 |
Oral administration of the extract from Hatakeshimeji (Lyophyllum decastes sing.) mushroom inhibits the development of atopic dermatitis-like skin lesions in NC/Nga mice.
Topics: Administration, Oral; Agaricales; Animals; Concanavalin A; Dermatitis, Atopic; Disease Models, Anima | 2007 |
Effect of TRFK-5 on airway responsiveness in ovalbumin-treated guinea pigs exposed to tobacco smoke.
Topics: Animals; Antibodies, Monoclonal; Bronchial Hyperreactivity; Capsaicin; Cell Movement; Disease Models | 2007 |
Involvement of brain endogenous histamine in the degeneration of dopaminergic neurons in 6-hydroxydopamine-lesioned rats.
Topics: Analysis of Variance; Animals; Behavior, Animal; Brain; Cell Count; Disease Models, Animal; Dopamine | 2007 |
Loss of capsaicin-induced meningeal neurogenic sensory vasodilatation in diabetic rats.
Topics: Acetylcholine; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Diabetes Mellitus, Experimental; | 2007 |
Stroke induces histamine accumulation and mast cell degranulation in the neonatal rat brain.
Topics: Age Factors; Animals; Animals, Newborn; Biomarkers; Brain; Cell Count; Cell Death; Chemotaxis, Leuko | 2008 |
Contribution of prostaglandin D2 via prostanoid DP receptor to nasal hyperresponsiveness in guinea pigs repeatedly exposed to antigen.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Administration, Intranasal; Alle | 2008 |
Acute exposure to a moderate strength static magnetic field reduces edema formation in rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 2008 |
Impact of CD40 ligand, B cells, and mast cells in peanut-induced anaphylactic responses.
Topics: Anaphylaxis; Animals; Antibodies; B-Lymphocytes; Body Temperature; CD40 Ligand; Cell Degranulation; | 2007 |
Magnetic therapy for edema in inflammation: a physiological assessment.
Topics: Animals; Calcium; Calcium Channels, L-Type; Carrageenan; Disease Models, Animal; Dose-Response Relat | 2008 |
Polygoni cuspidati radix inhibits the activation of Syk kinase in mast cells for antiallergic activity.
Topics: Anaphylaxis; Animals; Anti-Allergic Agents; Antigens; Bone Marrow Cells; Cell Line; Disease Models, | 2007 |
Anti-inflammatory and anti-nociceptive activities of Fumaria indica whole plant extract in experimental animals.
Topics: Acetic Acid; Administration, Oral; Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Cotto | 2007 |
Single-dose versus two-dose dexamethasone effects on lung inflammation and airway reactivity in meconium-instilled rabbits.
Topics: Animals; Anti-Inflammatory Agents; Bronchial Provocation Tests; Bronchoconstriction; Bronchoconstric | 2007 |
Intratracheally administered corticosteroids improve lung function in meconium-instilled rabbits.
Topics: Adrenal Cortex Hormones; Animals; Bronchial Provocation Tests; Bronchoconstriction; Bronchoconstrict | 2007 |
Aminophylline treatment in meconium-induced acute lung injury in a rabbit model.
Topics: Aminophylline; Animals; Anti-Inflammatory Agents; Bronchial Provocation Tests; Bronchoconstriction; | 2007 |
Evaluation of the cough reflex and airway reactivity in toluene- and ovalbumin-induced airway hyperresponsiveness.
Topics: Airway Resistance; Animals; Bronchial Provocation Tests; Bronchoconstriction; Bronchoconstrictor Age | 2007 |
Effects of multiple dexamethasone treatments on aggravation of allergic conjunctivitis associated with mast cell hyperplasia.
Topics: Allergens; Animals; Antigens, Plant; Cell Count; Conjunctivitis, Allergic; Cryptomeria; Dexamethason | 2008 |
Suppression of ischaemia-induced cytokine release by dimaprit and amelioration of liver injury in rats.
Topics: Adenosine Triphosphate; Alanine Transaminase; Animals; Aspartate Aminotransferases; Cytokines; Dimap | 2008 |
[The pathogenetic role of the serotonin-histamine-cyclic nucleotide system in ulcerogenesis].
Topics: Adolescent; Adult; Aged; Animals; Disease Models, Animal; Disease Progression; Endoscopy, Gastrointe | 2008 |
Effects of a Dictamnus dasycarpus T. extract on allergic models in mice.
Topics: Animals; Dictamnus; Disease Models, Animal; Dose-Response Relationship, Drug; Histamine; Hypersensit | 2008 |
Mast cell inhibition and reduced ventricular arrhythmias in a swine model of acute myocardial infarction upon therapeutic administration of relaxin.
Topics: Animals; Arrhythmias, Cardiac; Disease Models, Animal; Heart Ventricles; Histamine; Humans; Male; Ma | 2008 |
Atomoxetine increases histamine release and improves learning deficits in an animal model of attention-deficit hyperactivity disorder: the spontaneously hypertensive rat.
Topics: Adrenergic Uptake Inhibitors; Animals; Atomoxetine Hydrochloride; Attention Deficit Disorder with Hy | 2008 |
Effects of vaccination with heat shock proteins on streptozotocin induced diabetes in histidine decarboxylase knockout mice.
Topics: Animals; Antibodies, Anti-Idiotypic; Bacterial Proteins; Blood Glucose; Chaperonin 60; Chaperonins; | 2008 |
Acute effects of calvarial damage on dural mast cells, pial vascular permeability, and cerebral cortical histamine levels in rats and mice.
Topics: Albumins; Animals; Blood-Brain Barrier; Cerebral Arteries; Cerebral Cortex; Chemotaxis; Craniocerebr | 2008 |
Progress in allergy signal research on mast cells: up-regulation of histamine signal-related gene expression in allergy model rats.
Topics: Animals; Dexamethasone; Disease Models, Animal; Gene Expression Regulation; HeLa Cells; Histamine; H | 2008 |
Aqueous extract of rhubarb stabilizes vulnerable atherosclerotic plaques due to depression of inflammation and lipid accumulation.
Topics: Animals; Anticholesteremic Agents; Aorta, Abdominal; Aortic Rupture; Atherosclerosis; Cholesterol, H | 2008 |
Effect of olopatadine hydrochloride, an anti-histamine drug, on rhinitis induced by intranasal instillation of toluene-2,4-diisocyanate in rats.
Topics: Animals; Anti-Allergic Agents; Dibenzoxepins; Disease Models, Animal; Histamine; Histamine H1 Antago | 2008 |
The functional and morphological effects of duodeno-gastric reflux and their relation to peptic ulceration.
Topics: Animals; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Duodenal Diseases; Duodenum | 1983 |
The effects of Haemophilus influenzae vaccination on anaphylactic mediator release and isoprenaline-induced inhibition of mediator release.
Topics: Anaphylaxis; Animals; Arachidonic Acids; Asthma; Autacoids; Bradykinin; Bronchial Spasm; Disease Mod | 1980 |
Role of mast cell mediators in pathogenesis of anaphylactic gastric ulcer.
Topics: Anaphylaxis; Animals; Cells, Cultured; Disease Models, Animal; Heparin; Histamine; Histamine Release | 1983 |
[Ulcer-protective effect of cimetidine and an antacid. Animal experiment study on an ulcer model with protracted histamine liberation].
Topics: Animals; Antacids; Cimetidine; Disease Models, Animal; Guinea Pigs; Histamine; Histamine Release; Ma | 1984 |
Partial beta-adrenergic receptor blockade in experimental bronchial asthma.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Asthma; Cyclic AMP; Disease Models, Animal; Guinea Pig | 1980 |
Inflammatory responses to mast cell granules.
Topics: Animals; Cytoplasmic Granules; Disease Models, Animal; Eosinophils; Histamine; Humans; Hypersensitiv | 1984 |
Heightened cholinergic responsiveness in IgE-producing rabbits.
Topics: Animals; Carbachol; Disease Models, Animal; Histamine; Hypersensitivity, Immediate; Immunoglobulin E | 1984 |
A technique for monitoring respiratory responses in guinea pigs.
Topics: Animals; Animals, Laboratory; Asthma; Disease Models, Animal; Female; Guinea Pigs; Histamine; Microc | 1984 |
Comparative study on acute gastric mucosal lesion in experimental obstructive jaundice and biliary drainage models.
Topics: Animals; Bile; Cholestasis; Disease Models, Animal; Drainage; Gastric Mucosa; Histamine; Liver; Male | 1983 |
Histamine, cortisol and organ changes in fatal anaphylactic shock in guinea-pigs.
Topics: Anaphylaxis; Animals; Blood Glucose; Disease Models, Animal; Fatty Acids; Guinea Pigs; Histamine; Hy | 1984 |
[Experimental models for peptic ulcer].
Topics: Animals; Aspirin; Disease Models, Animal; Dogs; Histamine; Immersion; Indomethacin; Peptic Ulcer; Ra | 1984 |
Anti-inflammatory effects of praseodymium, gadolinium and ytterbium chlorides.
Topics: Animals; Anti-Inflammatory Agents; Arthritis; Capillary Permeability; Chlorides; Disease Models, Ani | 1984 |
Ascaris-induced allergic asthma in the conscious dog: a model for the pharmacologic modulation of immediate type hypersensitivity.
Topics: Animals; Antigens; Ascaris; Asthma; Bronchial Spasm; Disease Models, Animal; Dogs; Female; Histamine | 1982 |
Bronchial hyperreactivity associated with tracheal gangliosides.
Topics: Animals; Asthma; Bronchial Spasm; Carbohydrate Sequence; Disease Models, Animal; Gangliosides; Glyco | 1982 |
Rat serum sickness: possible role of inflammatory mediators allowing deposition of immune complexes in the glomerular basement membrane.
Topics: Animals; Antibodies; Antigen-Antibody Complex; Basement Membrane; Disease Models, Animal; Histamine; | 1982 |
Magnesium deficiency allergy-like crisis in hairless rats: a suggested model for inflammation studies.
Topics: Animals; Disease Models, Animal; Eosinophils; Histamine; Hypersensitivity; Leukocyte Count; Magnesiu | 1980 |
Praomys (Mastomys) natalensis: animal model for study of histamine-induced duodenal ulcers.
Topics: Animals; Cimetidine; Cysteamine; Disease Models, Animal; Duodenal Ulcer; Female; Gastrins; Guinea Pi | 1981 |
Relative allergenicity of cow's milk and cow's milk-based formulas in an animal model.
Topics: Allergens; Anaphylaxis; Animals; Bronchial Spasm; Calcium Channel Blockers; Cattle; Chloride Channel | 1995 |
Role of protein kinase C-mediated pathway in the pathogenesis of coronary artery spasm in a swine model.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1994 |
Histamine-mediated neuronal death in a rat model of Wernicke's encephalopathy.
Topics: Animals; Cell Death; Disease Models, Animal; Gliosis; Glutamic Acid; Glutamine; Hippocampus; Histami | 1994 |
Inhibition of hind-paw edema and cutaneous vascular plasma extravasation in mice by acetylshikonin.
Topics: Adrenalectomy; Animals; Anthraquinones; Bradykinin; Capillary Permeability; Cell Degranulation; Dexa | 1995 |
Enhancement of fibroblast-dependent mast cell growth in mice by a conditioned medium of keratinocyte-derived squamous cell carcinoma cells.
Topics: Animals; Carcinoma, Squamous Cell; Cytokines; Disease Models, Animal; Growth Substances; Hematopoiet | 1994 |
Time sequence of histamine release and formation in rat endotoxic shock.
Topics: Animals; Disease Models, Animal; Female; Histamine; Histamine Release; Histidine Decarboxylase; Kine | 1994 |
Inhibition by actinomycin D of neurogenic mouse ear oedema.
Topics: Animals; Bradykinin; Calcimycin; Calcitonin Gene-Related Peptide; Capsaicin; Cycloheximide; Dactinom | 1995 |
Inhibition of some aspects of acute inflammation of guinea-pig lung by intraperitoneal dexamethasone and mifepristone: demonstration of agonist activity of mifepristone in the guinea-pig.
Topics: Acute Disease; Animals; Blood Proteins; Bronchoalveolar Lavage Fluid; Dexamethasone; Disease Models, | 1995 |
Evidence for the involvement of histamine in the antidystonic effects of diphenhydramine.
Topics: Animals; Diphenhydramine; Disease Models, Animal; Dose-Response Relationship, Drug; Dystonia; Halope | 1995 |
Effects of an antibody to interleukin-5 in a monkey model of asthma.
Topics: Animals; Antibodies, Monoclonal; Ascaris suum; Asthma; Bronchial Hyperreactivity; Bronchoalveolar La | 1995 |
Contribution of platelet activating factor (PAF) in histamine-induced model of nasal allergy in rats.
Topics: Animals; Disease Models, Animal; Histamine; Male; Nasal Mucosa; Permeability; Platelet Activating Fa | 1995 |
Inhibitory effects of aspirin on coronary hyperreactivity to autacoids after arterial balloon injury in miniature pigs.
Topics: Angiography; Angioplasty, Balloon, Coronary; Animals; Aspirin; Autacoids; Blood Pressure; Constricti | 1995 |
Dysfunction of muscarinic M2 receptors after the early allergic reaction: possible contribution to bronchial hyperresponsiveness in allergic guinea-pigs.
Topics: Administration, Inhalation; Allergens; Animals; Asthma; Benzodiazepinones; Bronchial Hyperreactivity | 1995 |
Phosphodiesterase inhibitors reduce bronchial hyperreactivity and airway inflammation in unrestrained guinea pigs.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Administration, Inhalation; Analysis of Variance; Animals; Asth | 1995 |
Triggering of plaque disruption and arterial thrombosis in an atherosclerotic rabbit model.
Topics: Animals; Arteriosclerosis; Cholesterol; Cholesterol, Dietary; Coronary Thrombosis; Disease Models, A | 1995 |
Role of indomethacin-induced peptic ulceration in gastric acid secretion in pregnant rats.
Topics: Animals; Carbachol; Disease Models, Animal; Female; Gastric Acid; Histamine; Indomethacin; Peptic Ul | 1993 |
Cimetidine and omeprazole accelerate gastric ulcer healing by an increase in gastrin secretion.
Topics: Analysis of Variance; Animals; Cimetidine; Disease Models, Animal; Drug Interactions; Drug Synergism | 1994 |
Antiinflammatory effect of flavonoids in the natural juice from Aronia melanocarpa, rutin and rutin-magnesium complex on an experimental model of inflammation induced by histamine and serotonin.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; | 1994 |
The effects of two anti-CD18 antibodies on antigen-induced airway hyperresponsiveness and leukocyte accumulation in the guinea pig.
Topics: Acetylcholine; Animals; Antibodies; Antigens, CD; Bronchial Hyperreactivity; Bronchoalveolar Lavage | 1994 |
Inhibition of phase III activity by acid in canine stomach.
Topics: Animals; Disease Models, Animal; Dogs; Duodenal Ulcer; Electrodes; Electrophysiology; Famotidine; Fe | 1994 |
[Enterosorption as a method for correction of biogenic amine levels in experimental bronchospasm].
Topics: Animals; Bronchial Spasm; Disease Models, Animal; Enterosorption; Histamine; Immunization; Rats; Ser | 1993 |
A novel animal model for investigating persistent airway hyperresponsiveness.
Topics: Alternaria; Animals; Antigens, Fungal; Bronchi; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fl | 1993 |
In vivo bronchodilator action of a novel K+ channel opener, KC 399, in the guinea pig.
Topics: Administration, Inhalation; Albuterol; Anesthesia; Animals; Antigens; Asthma; Benzopyrans; Bronchoco | 1994 |
Virus-induced airway inflammation and hyperresponsiveness in the guinea-pig is inhibited by levodropropizine.
Topics: Animals; Antitussive Agents; Bronchial Hyperreactivity; Bronchitis; Bronchoalveolar Lavage Fluid; Di | 1993 |
Role of the complement system in antigen-induced bronchoconstriction and changes in blood pressure in the guinea pig.
Topics: Animals; Antibodies; Antigens; Blood Pressure; Bradykinin; Bronchoconstriction; Complement Activatio | 1993 |
Effects of a new calcium antagonist, CD-832, on experimental coronary artery spasm in miniature pigs.
Topics: Animals; Calcium Channel Blockers; Coronary Vasospasm; Disease Models, Animal; Histamine; Infusions, | 1993 |
Role of sodium in antigen-induced contraction of tracheal smooth muscle in dogs.
Topics: Amiloride; Animals; Animals, Newborn; Antigens; Bronchoconstriction; Disease Models, Animal; Dogs; D | 1993 |
Preferential concentration of azithromycin in an infected mouse thigh model.
Topics: Animals; Anti-Bacterial Agents; Azithromycin; Disease Models, Animal; Dose-Response Relationship, Dr | 1993 |
Comparative effects of tetrandrine and berbamine on guineapig airway microvascular leakage induced by platelet-activating factor and other allergic mediators.
Topics: Alkaloids; Animals; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Benzylisoquinolines; Bradykinin | 1993 |
Pharmacological options for the treatment of acute ureteric colic. An in vitro experimental study.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Colic; Disease Models, Animal; Dogs | 1993 |
Relationship between airway eosinophilia and airway hyperresponsiveness in a late asthmatic model of guinea pigs.
Topics: Animals; Antibodies; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar | 1996 |
Methacholine-induced histamine liberation during airway challenge tests in Ascaris skin-sensitive sheep.
Topics: Aerosols; Airway Obstruction; Airway Resistance; Allergens; Animals; Ascaris; Bronchial Provocation | 1995 |
Studies on antiulcer agents. IV. Antiulcer effects of 2-benzylthio5,6,7,8-tetrahydro-4(3H)-quinazolinones and related compounds.
Topics: Animals; Anti-Ulcer Agents; Aspirin; Cimetidine; Disease Models, Animal; Duodenal Ulcer; Epirizole; | 1995 |
The effects of three models of airway disease on tidal breathing flow-volume loops of thoroughbred horses.
Topics: Administration, Inhalation; Aerosols; Airway Resistance; Animals; Bronchoconstrictor Agents; Disease | 1995 |
Histamine forming capacity (HFC) and its modulation by H3 receptor ligands in a model of bronchial hyper-responsiveness.
Topics: Animals; Binding Sites; Bronchial Hyperreactivity; Disease Models, Animal; Dose-Response Relationshi | 1996 |
Models with clinically-relevant and life-threatening histamine-related cardiovascular disturbances: evaluation of the clinical effectiveness of H1/H2-histamine receptor antagonists in perioperative histamine release.
Topics: Animals; Blood Pressure; Chi-Square Distribution; Disease Models, Animal; Dogs; Female; Histamine; H | 1996 |
Role of interleukin-5 and substance P in development of airway hyperreactivity to histamine in guinea-pigs.
Topics: Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cells, Cultured; Disease Models, A | 1996 |
The role of fibroblast growth factor-2 in the vascular effects of interleukin-1 beta in porcine coronary arteries in vivo.
Topics: Animals; Coronary Artery Disease; Coronary Vessels; Disease Models, Animal; Drug Synergism; Fibrobla | 1996 |
Depletion of enterochromaffin-like cell histamine increases histidine decarboxylase and chromogranin A mRNA levels in rat stomach by a gastrin-independent mechanism.
Topics: Animals; Anti-Ulcer Agents; Culture Techniques; Disease Models, Animal; Enterochromaffin Cells; Enzy | 1996 |
Gastric acid secretion after depletion of enterochromaffin-like cell histamine. A study with alpha-fluoromethylhistidine in rats.
Topics: Animals; Disease Models, Animal; Enterochromaffin Cells; Enzyme Inhibitors; Female; Gastric Acid; Ga | 1996 |
Rat stomach enterochromaffin-like cells are not stimulated by pylorus ligation. A biochemical and ultrastructural study.
Topics: Animals; Disease Models, Animal; Enterochromaffin Cells; Gastric Acid; Gastrins; Histamine; Ligation | 1996 |
Biphasic action of the histamine precursor L-histidine in the rat kindling model of epilepsy.
Topics: Amygdala; Animals; Disease Models, Animal; Electric Stimulation; Epilepsy; Histamine; Histidine; Kin | 1996 |
Transient increase of blood histamine level induced by pentagastrin. Continuous monitoring by in vivo microdialysis.
Topics: Animals; Cells, Cultured; Disease Models, Animal; Gastrectomy; Gastric Acid; Gastric Mucosa; Histami | 1996 |
Anti-allergic effect of an aqueous extract of wu-hu-tang.
Topics: Anaphylatoxins; Animals; Asthma; Cell Degranulation; Disease Models, Animal; Dose-Response Relations | 1997 |
The cytoprotective effect of iloprost against carbon tetrachloride induced necrosis in rat liver.
Topics: Animals; Carbon Tetrachloride; Dinoprostone; Disease Models, Animal; Female; Histamine; Hypertension | 1997 |
Histamine (H1) receptor antagonist inhibits leukocyte rolling in pial vessels in the early phase of bacterial meningitis in rats.
Topics: Animals; Diphenhydramine; Disease Models, Animal; Histamine; Leukocytes; Male; Meningitis, Bacterial | 1997 |
Cyclosporin inhibits intercellular adhesion molecule-1 expression and reduces mast cell numbers in the asebia mouse model of chronic skin inflammation.
Topics: Animals; Cell Count; Cyclosporine; Dermatitis; Disease Models, Animal; Gene Expression; Histamine; I | 1997 |
[Studies on Kochiae Fructus. I. Antipruritogenic effect of 70% ethanol extract from kochiae fructus and its active component].
Topics: Animals; Antipruritics; Disease Models, Animal; Drugs, Chinese Herbal; Ethanol; Histamine; Male; Mic | 1997 |
The effect of R 15.7/HO, an anti-CD18 antibody, on the late airway response and airway hyperresponsiveness in an allergic rabbit model.
Topics: Alternaria; Animals; Antibodies, Monoclonal; Asthma; Bronchoalveolar Lavage; CD18 Antigens; Disease | 1997 |
[Intercellular interactions during the healing of an experimental skin wound].
Topics: Animals; Cell Communication; Disease Models, Animal; Fibroblasts; Histamine; Mast Cells; Rats; Rats, | 1997 |
[Mast cells in a focus of carrageenan-induced acute aseptic inflammation].
Topics: Acute Disease; Animals; Carrageenan; Disease Models, Animal; Escherichia coli Infections; Histamine; | 1997 |
[The mechanisms of the stimulating effect of tissue basophils on the reparative processes in inflammation].
Topics: Acute Disease; Animals; Autoradiography; Disease Models, Animal; Escherichia coli Infections; Hepari | 1997 |
Acute myocardial infarction enhances the portal venous histamine level in dogs.
Topics: Animals; Blood Pressure; Digestive System; Disease Models, Animal; Dogs; Female; Heart Rate; Histami | 1997 |
Sex, gonads, sex hormones and histamine-stimulated gastric acid and serum pepsinogen.
Topics: Animals; Body Weight; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Duodenal Ulcer | 1997 |
Effect of beta 2-agonists on histamine-induced airway microvascular leakage in ozone-exposed guinea pigs.
Topics: Adrenergic beta-Agonists; Airway Resistance; Albuterol; Animals; Blood-Air Barrier; Bronchial Hyperr | 1997 |
Effect of exercise training and food restriction on endothelium-dependent relaxation in the Otsuka Long-Evans Tokushima Fatty rat, a model of spontaneous NIDDM.
Topics: Abdomen; Adipose Tissue; Animals; Blood Glucose; Body Composition; Body Weight; Cholesterol; Diabete | 1998 |
Microvascular permeability with sulfonylureas in normal and diabetic hamsters.
Topics: Animals; Calcium Channel Blockers; Calcium Channels; Capillary Permeability; Cricetinae; Dextrans; D | 1997 |
Role of substance P in experimental allergic conjunctivitis in guinea pigs.
Topics: Animals; Capillary Permeability; Capsaicin; Conjunctiva; Conjunctivitis, Allergic; Dipeptides; Disea | 1997 |
Role of sensory innervation and mast cells in neurogenic plasma protein exudation into the airway lumen.
Topics: Analysis of Variance; Animals; Blood Proteins; Bronchoalveolar Lavage Fluid; Capillary Permeability; | 1997 |
Effects of high thoracic epidural anaesthesia on the peripheral airway reactivity in dogs.
Topics: Acetylcholine; Airway Resistance; Analysis of Variance; Anesthesia, Epidural; Anesthetics, Local; An | 1998 |
Effects of cyclosporin A and glucocorticosteroids on antigen-induced hypersensitivity to histamine in a guinea pig model of allergic rhinitis.
Topics: Administration, Inhalation; Androstadienes; Animals; Anti-Allergic Agents; Anti-Inflammatory Agents; | 1998 |
Effects of anti-IL-5 monoclonal antibody on the murine model of nasal allergy.
Topics: Allergens; Animals; Antibodies, Monoclonal; Disease Models, Animal; Dose-Response Relationship, Drug | 1998 |
Involvement of free radicals and histamine in the potentiating action of cigarette smoke exposure on ethanol-induced gastric mucosal damage in rats.
Topics: Animals; Disease Models, Animal; Ethanol; Free Radicals; Gastric Mucosa; Histamine; Histamine H1 Ant | 1998 |
Long-term effects of portacaval anastomosis on the 5-hydroxytryptamine, histamine, and catecholamine neurotransmitter systems in rat brain.
Topics: Animals; Biogenic Monoamines; Brain; Catecholamines; Disease Models, Animal; Hepatic Encephalopathy; | 1998 |
Increase in histamine production by inflammatory exudate in the chronic phase of allergic inflammation in rats.
Topics: Animals; Chronic Disease; Disease Models, Animal; Exudates and Transudates; Granulocyte-Macrophage C | 1998 |
Dual action of iNOS-derived nitric oxide in allergen-induced airway hyperreactivity in conscious, unrestrained guinea pigs.
Topics: Acute Disease; Adjuvants, Immunologic; Allergens; Animals; Asthma; Bronchial Hyperreactivity; Bronch | 1998 |
Biphasic elevation of plasma histamine induced by water immersion stress, and their sources in rats.
Topics: Animals; Disease Models, Animal; Gastrectomy; Gastric Mucosa; Histamine; Histidine Decarboxylase; Ma | 1998 |
Oral anti-inflammatory action of NPC 18884, a novel bradykinin B2 receptor antagonist.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bradykinin; Bradykinin Recep | 1998 |
Involvement of tachykinin NK1 receptor in the development of allergen-induced airway hyperreactivity and airway inflammation in conscious, unrestrained guinea pigs.
Topics: Allergens; Animals; Asthma; Bronchi; Bronchial Hyperreactivity; Bronchial Provocation Tests; Broncho | 1999 |
A murine model of IgE-mediated cow's milk hypersensitivity.
Topics: Adjuvants, Immunologic; Anaphylaxis; Animals; Capillary Permeability; Caseins; Cell Degranulation; C | 1999 |
Suppressive effects of CTLA4-Ig on nasal allergic reactions in presensitized murine model.
Topics: Abatacept; Animals; Antigens, CD; Antigens, Differentiation; CTLA-4 Antigen; Cytokines; Disease Mode | 1999 |
Arterially perfused eye model of uveitis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cats; Ciliary Arteries; Clonixin; Complement C5a; | 1999 |
Oral gene delivery with chitosan--DNA nanoparticles generates immunologic protection in a murine model of peanut allergy.
Topics: 2S Albumins, Plant; Administration, Oral; Anaphylaxis; Animals; Antibodies; Antigens, Plant; Arachis | 1999 |
Pharmacological evaluation of an in vivo model of vestibular dysfunction in the rat.
Topics: Animals; Betahistine; Disease Models, Animal; Drug Interactions; Excitatory Amino Acid Agonists; His | 1999 |
A new rat model of otitis media caused by Streptococcus pneumoniae: conditions and application in immunization protocols.
Topics: Animals; Bacterial Vaccines; Disease Models, Animal; Female; Histamine; Otitis Media; Pneumococcal I | 1999 |
Difference in bronchoprotective effects of bronchodilators on postallergic propranolol-induced bronchoconstriction.
Topics: Airway Resistance; Albuterol; Aminophylline; Animals; Atropine; Bronchi; Bronchial Hyperreactivity; | 1999 |
Animal model of sclerotic skin. II. Bleomycin induced scleroderma in genetically mast cell deficient WBB6F1-W/W(V) mice.
Topics: Animals; Antibiotics, Antineoplastic; Biopsy; Bleomycin; Cell Count; Disease Models, Animal; Female; | 1999 |
Nasal hyperresponsiveness to histamine induced by repetitive exposure to cedar pollen in guinea-pigs.
Topics: Administration, Inhalation; Airway Resistance; Allergens; Animals; Atropine; Disease Models, Animal; | 1999 |
Increased histamine release and granulocytes within the thalamus of a rat model of Wernicke's encephalopathy.
Topics: Animals; Basophils; Behavior, Animal; Cerebrovascular Circulation; Disease Models, Animal; Hippocamp | 2000 |
Role of mast cells in the pathogenesis of postburn inflammatory response: reactive oxygen species as mast cell stimulators.
Topics: Animals; Biomarkers; Burns; Cell Degranulation; Chymases; Disease Models, Animal; Histamine; Male; M | 2000 |
The effect of dopamine on the rapidly adapting receptors in the dog lung.
Topics: Adrenergic beta-Agonists; Airway Resistance; Animals; Asthma; Chemoreceptor Cells; Disease Models, A | 2000 |
[The mechanisms for the decrease in gastric motor-evacuatory function after performing a vagotomy].
Topics: Adipates; Animals; Disease Models, Animal; Gastric Emptying; Histamine; Male; Peptic Ulcer; Postoper | 1999 |
Changes in histamine content following pharmacologically-induced mast cell degranulation in the rat conjunctiva.
Topics: Animals; Cell Degranulation; Conjunctiva; Conjunctivitis, Allergic; Cromolyn Sodium; Disease Models, | 2000 |
Experimental allergic conjunctivitis in guinea pigs induced by Japanese cedar pollen.
Topics: Animals; Anti-Allergic Agents; Capillary Permeability; Conjunctivitis, Allergic; Disease Models, Ani | 2000 |
Interleukin-2 and histamine in combination inhibit tumour growth and angiogenesis in malignant glioma.
Topics: Animals; Brain Neoplasms; Disease Models, Animal; Drug Therapy, Combination; Glioma; Histamine; Inte | 2000 |
CNS induced neurogenic cystitis is associated with bladder mast cell degranulation in the rat.
Topics: Administration, Intravesical; Analysis of Variance; Animals; Capsaicin; Cell Degranulation; Central | 2000 |
Do muscle relaxants influence vascular tone in isolated coronary artery segments?
Topics: Acetylcholine; Androstanols; Animals; Atracurium; Coronary Vessels; Disease Models, Animal; Dose-Res | 2000 |
Induction of active systemic anaphylaxis by oral sensitization with ovalbumin in mast-cell-deficient mice.
Topics: Administration, Oral; Anaphylaxis; Animals; Body Weight; Disease Models, Animal; Female; Fever; Food | 2000 |
Modulation of histamine H3 receptors in the brain of 6-hydroxydopamine-lesioned rats.
Topics: Amygdala; Animals; Brain; Corpus Striatum; Disease Models, Animal; Functional Laterality; Gene Expre | 2000 |
Effect of ricinoleic acid in acute and subchronic experimental models of inflammation.
Topics: Acute Disease; Administration, Topical; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, | 2000 |
Control of renin secretion from adrenal gland in transgenic Ren-2 and normal rats.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitor | 2001 |
Role of chemical mediators in airway hyperresponsiveness in an asthmatic model.
Topics: Airway Resistance; Animals; Asthma; Bronchial Hyperreactivity; Disease Models, Animal; Dose-Response | 2001 |
Protective effect of a PAR2-activating peptide on histamine-induced bronchoconstriction in guinea-pig.
Topics: Analysis of Variance; Animals; Bronchial Spasm; Bronchoconstriction; Disease Models, Animal; Guinea | 2001 |
Effect of purified lipopolysaccharides from strains of Helicobacter pylori and Helicobacter felis on acid secretion in mouse gastric glands in vitro.
Topics: Animals; Carbachol; Dinoprostone; Disease Models, Animal; Duodenal Ulcer; Female; Gastric Acid; Gast | 2001 |
Inhibition of immunologic and nonimmunologic stimulation-mediated anaphylactic reactions by water extract of white eggplant (Solanum melongena).
Topics: Administration, Oral; Anaphylaxis; Animals; Biological Factors; Dinitrophenols; Disease Models, Anim | 2001 |
Novel findings in inhibition of mast cell-dependent immediate-type cutaneous reactions by Gahmi-Shini-San.
Topics: Alcian Blue; Animals; Cell Degranulation; Disease Models, Animal; Dose-Response Relationship, Drug; | 2001 |
Examination of oral sensitization with ovalbumin in Brown Norway rats and three strains of mice.
Topics: Administration, Oral; Age Factors; Allergens; Anaphylaxis; Animals; Disease Models, Animal; Female; | 2001 |
Physicochemical and biological evaluation of P792, a rapid-clearance blood-pool agent for magnetic resonance imaging.
Topics: Acute Kidney Injury; Animals; Contrast Media; Disease Models, Animal; Hemodynamics; Heterocyclic Com | 2001 |
Bronchial, alveolar, and vascular-induced anaphylaxis and irritant-induced cardiovascular and pulmonary responses.
Topics: Allergens; Anaphylaxis; Animals; Bronchi; Disease Models, Animal; Dogs; Female; Hemodynamics; Histam | 2001 |
[Modulating effects of exogenous histamine, serotonin, and heparin on leukocytic reaction during inflammation].
Topics: Animals; Disease Models, Animal; Escherichia coli Infections; Heparin; Histamine; Inflammation; Leuk | 2001 |
Antiischemic properties of fasudil in experimental models of vasospastic angina.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Angina Pectoris; Animals; Coronary Vasospasm; Disease | 2001 |
Decreased brain histamine content in hypocretin/orexin receptor-2 mutated narcoleptic dogs.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Brain Chemistry; Cerebral Cortex; Chromatography, Hi | 2001 |
Capsaicin-evoked CGRP release from rat buccal mucosa: development of a model system for studying trigeminal mechanisms of neurogenic inflammation.
Topics: Animals; Bradykinin; Calcimycin; Calcitonin Gene-Related Peptide; Calcium; Capsaicin; Dinoprostone; | 2001 |
Selective protective effects of nitric oxide inhalation on allergen-induced acute airway reactions in the pig.
Topics: Administration, Inhalation; Aerosols; Airway Resistance; Allergens; Animals; Blood Gas Analysis; Blo | 2001 |
Bronchodilatory and anti-inflammatory properties of inhaled selective phosphodiesterase inhibitors in a guinea pig model of allergic asthma.
Topics: Administration, Inhalation; Allergens; Animals; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Bro | 2001 |
Enhanced expression of mucin genes in a guinea pig model of allergic asthma.
Topics: Amino Acid Sequence; Animals; Antineoplastic Agents; Asthma; Base Sequence; Bronchial Hyperreactivit | 2001 |
Relationship between intracellular calcium and airway reactivity in guinea pigs.
Topics: Administration, Inhalation; Animals; Asthma; Calcium; Calcium-Transporting ATPases; Disease Models, | 2001 |
Gastric antisecretory and antiulcer activity of oxytocin in rats and guinea pigs.
Topics: Acetic Acid; Acute Disease; Animals; Anti-Ulcer Agents; Chronic Disease; Cysteamine; Disease Models, | 2001 |
LPS-sensory peptide communication in experimental cystitis.
Topics: Administration, Intravesical; Animals; Contrast Media; Cystitis; Disease Models, Animal; Drug Synerg | 2002 |
ReN 1869, a novel tricyclic antihistamine, is active against neurogenic pain and inflammation.
Topics: Animals; Benzoquinones; Binding Sites; Calcitonin Gene-Related Peptide; Calcium; Calcium Channels; C | 2002 |
Antipruritic activity of the kappa-opioid receptor agonist, TRK-820.
Topics: Animals; Antipruritics; Chlorpheniramine; Disease Models, Animal; Histamine; Histamine H1 Antagonist | 2002 |
Increased gastric acid secretion in cholecystokinin-1 receptor-deficient Otsuka Long-Evans Tokushima fatty rats.
Topics: Animals; Cholecystokinin; Disease Models, Animal; Gastric Acid; Gastrins; Histamine; Male; Paracrine | 2002 |
Experimental stereotactic gamma knife radiosurgery. Vascular contractility studies of the rat middle cerebral artery after chronic survival.
Topics: Animals; Arginine; Dinoprost; Disease Models, Animal; Dose-Response Relationship, Drug; Histamine; I | 2002 |
Neuronal storage of histamine in the brain and tele-methylimidazoleacetic acid excretion in portocaval shunted rats.
Topics: Animals; Animals, Outbred Strains; Brain; Disease Models, Animal; Food Deprivation; Gastrectomy; Hep | 2002 |
[Mediators causing urticaria].
Topics: Allergens; Angioedema; Animals; Chemokines; Chronic Disease; Cytokines; Disease Models, Animal; Guin | 2001 |
Mycobacterium avium subspecies paratuberculosis triggers intestinal pathophysiologic changes in beige/scid mice.
Topics: Animals; Disease Models, Animal; Electric Stimulation; Electrophysiology; Female; Glucose; Histamine | 2001 |
Exercise training improves acetylcholine-induced endothelium-dependent hyperpolarization in type 2 diabetic rats, Otsuka Long-Evans Tokushima fatty rats.
Topics: Acetylcholine; Age Factors; Animals; Aorta, Abdominal; Aorta, Thoracic; Biological Factors; Blood Gl | 2002 |
Effect of intranasal histamine challenge on Eustachian tube function.
Topics: Administration, Intranasal; Animals; Disease Models, Animal; Eustachian Tube; Histamine; Male; Otiti | 2002 |
Elevated nasal mucosal G protein levels and histamine receptor affinity in a guinea pig model of nasal hyperresponsiveness.
Topics: Animals; Area Under Curve; Binding, Competitive; Blotting, Western; Disease Models, Animal; GTP-Bind | 2002 |
Effects of cimetidine, a histamine H2-receptor antagonist, on various experimental gastric and duodenal ulcers.
Topics: Administration, Oral; Animals; Aspirin; Carbachol; Depression, Chemical; Disease Models, Animal; Duo | 1977 |
Pathogenesis of duodenal ulceration produced by cysteamine or propionitrile: influence of vagotomy, sympathectomy, histamine depletion, H-2 receptor antagonists and hormones.
Topics: Adrenalectomy; Animals; Castration; Cimetidine; Cysteamine; Disease Models, Animal; Duodenal Ulcer; | 1979 |
The effects of histamine liberators and exogenous histamine on wound healing in rat.
Topics: Adenosine Triphosphate; Animals; Biomechanical Phenomena; Collagen; Disease Models, Animal; Histamin | 1975 |
Effect of a low protein diet on the capacity of mice to express a type I hypersensitivity response.
Topics: Animals; Ascitic Fluid; Cell Count; Disease Models, Animal; Female; Histamine; Histamine Release; Hy | 1978 |
Is histamine a mediator in bile-induced gastric mucosal injury?
Topics: Animals; Bile; Cimetidine; Disease Models, Animal; Dogs; Gastric Mucosa; Histamine; Histamine Releas | 1978 |
Histamine and pancreatitis: increase of plasma histamine levels in dogs with Pfeffer preparation and influence of aminoguanidine on the survival time.
Topics: Acute Disease; Amine Oxidase (Copper-Containing); Animals; Disease Models, Animal; Dogs; Duodenum; F | 1978 |
Ascaris-induced respiratory responses in the conscious rhesus monkey.
Topics: Aerosols; Animals; Antigens; Ascaris; Cromolyn Sodium; Disease Models, Animal; Female; Haplorhini; H | 1979 |
Endotoxin-induced histamine hypersensitivity in mice. . . a model system for byssinosis?
Topics: Animals; Byssinosis; Disease Models, Animal; Drug Hypersensitivity; Endotoxins; Gossypium; Histamine | 1979 |
The effect of prostaglandin E2, 15-methyl prostaglandin E2, and metiamide on established canine gastric mucosal barrier damage.
Topics: Administration, Topical; Animals; Aspirin; Cell Membrane Permeability; Disease Models, Animal; Dogs; | 1979 |
Relationship between inhibition of aortic histamine formation, aortic albumin permeability and atherosclerosis.
Topics: Animals; Aorta, Thoracic; Arteriosclerosis; Cholesterol, Dietary; Disease Models, Animal; Histamine; | 1979 |
The pulmonary alveolar capillary membrane during hemorrhagic hypotension in dogs.
Topics: Albumins; Animals; Capillaries; Dextrans; Disease Models, Animal; Dogs; Histamine; Hypotension; Math | 1978 |
Patterns of neoplastic and nonneoplastic diseases of Praomys (Mastomys) natalensis.
Topics: Animals; Carcinoid Tumor; Disease Models, Animal; Female; Glomerulonephritis; Histamine; Immunity; J | 1975 |
The effect of cholinergic and anticholinergic agents on the primate model of allergic asthma.
Topics: Airway Resistance; Animals; Antigens; Asthma; Atropine; Carbachol; Disease Models, Animal; Female; H | 1976 |
Airway hyperreactivity to pharmacologic agents in rhesus monkeys cutaneously hypersensitive to Ascaris antigen.
Topics: Airway Resistance; Animals; Antigens; Ascaris; Carbachol; Disease Models, Animal; Dose-Response Rela | 1976 |
Anaphylactic contraction of pulmonary blood vessels of chicken.
Topics: Acetylcholine; Anaphylaxis; Animals; Bradykinin; Chickens; Coronary Vessels; Disease Models, Animal; | 1977 |
Segmental gastric antral resection in experimental peptic ulceration.
Topics: Animals; Disease Models, Animal; Dogs; Gastrectomy; Gastroenterostomy; Histamine; Peptic Ulcer; Pylo | 1977 |
Experimental model of acute inflammation: acetic acid-induced pleurisy in rat.
Topics: Acetates; Animals; Blood Proteins; Disease Models, Animal; Histamine; Inflammation; Kininogens; Kini | 1977 |
The effect of cholinergic agents on a canine model of allergic asthma.
Topics: Administration, Intranasal; Airway Resistance; Animals; Antigens; Ascaris; Asthma; Atropine; Chloris | 1976 |
Proceedings: Histamine sensitivity in spontaneously hypertensive rats.
Topics: Animals; Capillary Permeability; Cerebrovascular Circulation; Disease Models, Animal; Histamine; Hyp | 1976 |
Effects of carbenoxolone Na on acute and chronic gastric ulcer models in experimental animals.
Topics: Acute Disease; Animals; Aspirin; Carbenoxolone; Chronic Disease; Disease Models, Animal; Dogs; Gastr | 1976 |
[Possible therapeutic influences on experimentally induced edemas (author's transl)].
Topics: Brain Edema; Cold Temperature; Disease Models, Animal; Edema; Escin; Histamine; Ischemia; Muscles; M | 1976 |
Canine airway responses to acetylcholine, prostaglandin F2alpha, histamine, and serotonin after chronic antigen exposure.
Topics: Acetylcholine; Airway Resistance; Animals; Antigens; Atropine; Disease Models, Animal; Dogs; Dose-Re | 1976 |
Experimental gastric ulcers in the fundic gland area following transplantation of the gastric-wall pedicles.
Topics: Animals; Disease Models, Animal; Dogs; Female; Histamine; Humans; Male; Pylorus; Sesame Oil; Stomach | 1976 |
Proceedings: An improved technique for producing hemorrhageous erosions in the female rat: its application in studies on the role of histamine in stress ulcer pathogenesis.
Topics: Animals; Disease Models, Animal; Female; Gastrointestinal Hemorrhage; Histamine; Immobilization; Met | 1975 |
[The possibilities and limitations of the use of rat paw edemas as models of inflammation. 2. Possible influence of the results in examinations on paw edemas].
Topics: Age Factors; Albumins; Animals; Bradykinin; Carrageenan; Consciousness; Dextrans; Disease Models, An | 1975 |
Mechanical properties of the lungs and experimental asthma in conscious allergic dogs.
Topics: Airway Resistance; Allergens; Animals; Ascaris; Asthma; Bronchi; Constriction; Disease Models, Anima | 1975 |
Arterial and muscle oxygen tension in experimental models of asthma. Experimental models of asthma.
Topics: Animals; Antibody Formation; Ascaris; Asthma; Catheterization; Choline; Disease Models, Animal; Dogs | 1975 |
Letter: Experimental asthma in conscious allergic dogs.
Topics: Airway Resistance; Animals; Antigens; Asthma; Atropine; Disease Models, Animal; Dogs; Histamine; Iso | 1975 |
Proceedings: Simple models of anaphylaxis and of histamine and 5-hydroxytryptamine induced inflammation using the mouse pinna.
Topics: Anaphylaxis; Animals; Disease Models, Animal; Ear; Histamine; Inflammation; Male; Mice; Mice, Inbred | 1975 |
Sulfur dioxide-induced bronchoconstriction via ruthenium red-sensitive activation of sensory nerves.
Topics: Animals; Bronchoconstriction; Calcitonin Gene-Related Peptide; Disease Models, Animal; Guinea Pigs; | 1992 |
The role of neutrophils in acute and chronic inflammation in rats.
Topics: Acute Disease; Animals; Arthritis, Experimental; Carrageenan; Chronic Disease; Disease Models, Anima | 1992 |
Repeated antigen challenge induced airway hyperresponsiveness to neurokinin A and vagal non-adrenergic, non-cholinergic (NANC) stimulation in guinea pigs.
Topics: Acetylcholine; Aerosols; Animals; Antigens; Bronchial Hyperreactivity; Capsaicin; Choline; Disease M | 1992 |
Direct evidence for increased continuous histamine release in the striatum of conscious freely moving rats produced by middle cerebral artery occlusion.
Topics: Animals; Brain Chemistry; Brain Ischemia; Cerebral Infarction; Corpus Striatum; Disease Models, Anim | 1992 |
Mechanisms contributing to ozone-induced bronchial hyperreactivity in guinea-pigs.
Topics: Adenine Nucleotides; Animals; Ascorbic Acid; Atropine; Bronchial Hyperreactivity; Bronchoconstrictio | 1992 |
Studies on the relationship between xanthine oxidase and histamine release during intestinal ischemia-reperfusion.
Topics: Animals; Cromolyn Sodium; Disease Models, Animal; Dogs; Female; Guanidines; Histamine; Histamine Rel | 1992 |
Possible contributory role of the central histaminergic system in the forced swimming model.
Topics: Animals; Antidepressive Agents; Brain Chemistry; Central Nervous System; Depressive Disorder; Diseas | 1992 |
Experimental arthritis in rats induced by intra-articular injection of IgE aggregates: evidence for arthritogenic role of complexed IgE.
Topics: Animals; Arthritis; Disease Models, Animal; Female; Histamine; Hyperplasia; Immunoglobulin E; Iodine | 1992 |
[Side effects of hemosorption in the treatment of acute hepatic insufficiency].
Topics: Acute Disease; Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Dise | 1992 |
Inhibitory effect of NZ-107 on anaphylactic bronchoconstriction in guinea pigs and rats.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Anaphylaxis; Anim | 1992 |
Effects of NZ-107 on bronchoconstriction in guinea pigs.
Topics: Albuterol; Animals; Asthma; Bronchoconstriction; Cromolyn Sodium; Disease Models, Animal; Guinea Pig | 1992 |
Changes in lung mechanics and histamine responsiveness after sequential canine adenovirus 2 and canine parainfluenza 2 virus infection in beagle puppies.
Topics: Adenoviridae Infections; Airway Resistance; Animals; Bronchiolitis, Viral; Disease Models, Animal; D | 1991 |
Characteristics of two lines of guinea pigs (BHS and BHR) differing in bronchial sensitivity to acetylcholine and histamine exposure.
Topics: Acetylcholine; Airway Resistance; Animals; Antibody Formation; Asthma; Disease Models, Animal; Femal | 1991 |
Nasal mucosal hypersensitivity in guinea pigs intermittently exposed to cold.
Topics: Animals; Cold Temperature; Disease Models, Animal; Guinea Pigs; Histamine; Immune Sera; Male; Methac | 1991 |
Potential role of histamine monochloramine in a rabbit model of ileitis.
Topics: Acute Disease; Animals; Cell Membrane Permeability; Chloramines; Chromium Radioisotopes; Disease Mod | 1991 |
Inflammatory mediators in cotton-top tamarins (CTT) with acute and chronic colitis.
Topics: Acute Disease; Animals; Chronic Disease; Colitis; Dinoprostone; Disease Models, Animal; Histamine; I | 1991 |
Downward regulation of neutrophil infiltration by endogenous histamine without affecting vascular permeability responses in air-pouch-type carrageenin inflammation in rats.
Topics: Anaphylaxis; Animals; Capillary Permeability; Carrageenan; Disease Models, Animal; Histamine; Histam | 1991 |
Mast cell hyperplasia in experimental hypersensitivity pneumonitis.
Topics: Alveolitis, Extrinsic Allergic; Animals; Bronchoalveolar Lavage Fluid; Cell Count; Cell Degranulatio | 1991 |
[Bronchial hyperresponsiveness to histamine following antigen challenges in actively sensitized guinea pigs].
Topics: Airway Resistance; Animals; Asthma; Disease Models, Animal; Guinea Pigs; Histamine; Lung Compliance; | 1991 |
Validation of a non-invasive technique to assess development of airway hyperreactivity in an animal model of immunologic pulmonary hypersensitivity.
Topics: Animals; Disease Models, Animal; Guinea Pigs; Histamine; Male; Ovalbumin; Plethysmography, Whole Bod | 1991 |
[Study on ear burn model in mice and its significant application].
Topics: Animals; Bradykinin; Burns; Capillary Permeability; Dexamethasone; Diphenhydramine; Disease Models, | 1990 |
A comparison in vitro of human and rabbit distal colonic muscle responses to inflammatory mediators.
Topics: Acetylcholine; Adolescent; Adult; Aged; Aged, 80 and over; Animals; Child; Colon; Disease Models, An | 1990 |
Relationship between nonspecific airway hyperreactivity and antigen-induced contraction in an allergic animal model in vitro.
Topics: Animals; Calcium Chloride; Disease Models, Animal; Guinea Pigs; Histamine; Injections, Intramuscular | 1990 |
Responses of equine trachealis and lung parenchyma to methacholine, histamine, serotonin, prostanoids, and leukotrienes in vitro.
Topics: Animals; Asthma; Atropine; Disease Models, Animal; Histamine; Horses; In Vitro Techniques; Indometha | 1990 |
Histamine and xanthine oxidase in hepatic ischemia-reperfusion injury.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Disease Models, Animal; Histamine; Ische | 1990 |
Effects of coenzyme Q10 in hemorrhagic shock.
Topics: Airway Resistance; Animals; Blood Gas Analysis; Coenzymes; Disease Models, Animal; Dogs; Hemodynamic | 1990 |
An experimental model of death from anaphylactic shock with compound 48/80 and postmortem changes in levels of histamine in blood.
Topics: Adult; Anaphylaxis; Animals; Cause of Death; Disease Models, Animal; Dogs; Female; Histamine; Humans | 1990 |
Increased metachromatic cells and lymphocytes in bronchoalveolar lavage fluid of dogs with airway hyperreactivity.
Topics: Animals; Body Fluids; Bronchi; Bronchial Provocation Tests; Bronchial Spasm; Citrates; Citric Acid; | 1986 |
Effects of mast cell stabilizers on a new bronchial asthma model using compound 48/80 in dogs.
Topics: Airway Resistance; Animals; Asthma; Blood Pressure; Chlorpheniramine; Cromolyn Sodium; Cyclohexaneca | 1987 |
Release and synthesis of histamine in rat basophilic leukemia (2H3) cells.
Topics: Animals; Cells, Cultured; Disease Models, Animal; Fluorescent Dyes; Histamine; Histamine Release; Hi | 1989 |
Round window membrane and perilymph in experimental otitis media with effusion.
Topics: Albumins; Animals; Chinchilla; Cochlea; Dinoprostone; Disease Models, Animal; Histamine; Immunoglobu | 1989 |
The pathophysiological role of kinin and chemical mediators on experimental allergic rhinitis.
Topics: Animals; Bradykinin; Capillary Permeability; Disease Models, Animal; Guinea Pigs; Histamine; Kinins; | 1989 |
Bronchial reactivities in guinea pigs to acetylcholine or histamine exposure.
Topics: Acetylcholine; Age Factors; Animals; Asthma; Bronchi; Bronchial Provocation Tests; Disease Models, A | 1989 |
Development of chronic airway hyperresponsiveness in ragweed-sensitized dogs.
Topics: Airway Resistance; Animals; Animals, Newborn; Asthma; Bronchoalveolar Lavage Fluid; Chronic Disease; | 1989 |
Healing process of duodenal ulcers induced by indomethacin plus histamine in rats.
Topics: Animals; Cimetidine; Disease Models, Animal; Duodenal Ulcer; Duodenum; Gastric Acid; Histamine; Hydr | 1989 |
Canine model of chronic bronchial injury. Lung mechanics and pathologic changes.
Topics: Animals; Bronchi; Bronchitis; Chronic Disease; Disease Models, Animal; Dogs; Histamine; Lung; Nitrat | 1988 |
A nasal allergy model developed in the guinea pig by intranasal application of 2,4-toluene diisocyanate.
Topics: Administration, Intranasal; Animals; Cyanates; Disease Models, Animal; Guinea Pigs; Histamine; Male; | 1988 |
Changes in autacoid and neuropeptide contents of lung cells in asbestos-induced pulmonary fibrosis.
Topics: Animals; Asbestosis; Autacoids; Bombesin; Disease Models, Animal; Histamine; Lung; Male; Microscopy, | 1987 |
Effects of prostacyclin, indomethacin, and thiothromboxane A2 on histamine-induced coronary spasm in atherosclerotic miniature swine.
Topics: Animals; Arteriosclerosis; Coronary Vasospasm; Disease Models, Animal; Epoprostenol; Histamine; Indo | 1985 |
Role of central histaminergic mechanism in behavioural depression (swimming despair) in mice.
Topics: Animals; Atropine; Central Nervous System; Cimetidine; Depression; Desipramine; Disease Models, Anim | 1988 |
In vivo and in vitro studies on the use of the guinea pig as a model for virus-provoked airway hyperreactivity.
Topics: Airway Resistance; Animals; Disease Models, Animal; Electric Stimulation; Female; Guinea Pigs; Hista | 1985 |
Experimental eosinophilia and inflammation--the effect of various inflammatory mediators and chemoattractants.
Topics: Acid Phosphatase; Animals; Arylsulfatases; Blood Proteins; Bradykinin; Carrageenan; Cell Movement; C | 1986 |
Prevention of canine anaphylaxis with isoproterenol.
Topics: Airway Resistance; Anaphylaxis; Animals; Blood Pressure; Cardiac Output; Cyclic AMP; Disease Models, | 1986 |
Attenuation of endothelium-related relaxation and enhanced responsiveness of vascular smooth muscle to histamine in spastic coronary arterial segments from miniature pigs.
Topics: Animals; Calcimycin; Coronary Vasospasm; Dinoprost; Disease Models, Animal; Endothelium, Vascular; H | 1987 |
A new rhinitis model using chemical mediators in rats.
Topics: Airway Resistance; Animals; Bradykinin; Capillary Permeability; Disease Models, Animal; Histamine; M | 1988 |
Mode of action of cell recruiting, specifically sensitized lymphocytes recovered from rejecting allografts.
Topics: Animals; Bradykinin; Capillary Permeability; Cell Movement; Disease Models, Animal; Graft Rejection; | 1988 |
Two patterns of early neutrophil accumulation in acute inflammatory lesions.
Topics: Acute Disease; Animals; Caseins; Cell Count; Desensitization, Immunologic; Disease Models, Animal; E | 1988 |
Comparison of drug responses in vivo and in vitro in airways of dogs with and without airway hyperresponsiveness.
Topics: Aerosols; Airway Resistance; Animals; Asthma; Bronchial Provocation Tests; Disease Models, Animal; D | 1986 |
Pathogenesis of coronary artery spasm in miniature swine with regional intimal thickening after balloon denudation.
Topics: Animals; Atropine; Calcium; Coronary Vasospasm; Coronary Vessels; Disease Models, Animal; Endotheliu | 1987 |
The structure and reactions of the microcirculation in a subcutaneous air pouch in the rat.
Topics: Animals; Arthritis, Experimental; Carrageenan; Connective Tissue; Disease Models, Animal; Female; Fi | 1987 |
[Lysosomal enzyme activity of the gastric mucosa in rats during experimental ulcer formation].
Topics: Acetates; Acetic Acid; Animals; Disease Models, Animal; Gastric Mucosa; Histamine; Lysosomes; Rats; | 1987 |
Base-line and postthermal injury plasma histamine in rats.
Topics: Animals; Blood Platelets; Burns; Disease Models, Animal; Histamine; Humans; Leukocytes; Male; Rats; | 1986 |
Phorbol myristate acetate lung injury and airway responsiveness to aerosol histamine in awake sheep.
Topics: Aerosols; Animals; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Immunologic; | 1986 |
Augmentation of cysteamine and mepirizole-induced lesions in the rat duodenum and stomach by histamine or indomethacin.
Topics: Animals; Cysteamine; Disease Models, Animal; Drug Synergism; Duodenal Ulcer; Epirizole; Histamine; I | 1986 |
Mast cells in newly formed lining tissue during acute inflammation: a six day air pouch model in the mouse.
Topics: Acute Disease; Animals; Carrageenan; Disease Models, Animal; Exudates and Transudates; Histamine; In | 1986 |
Histamine-induced spasm not significantly modulated by prostanoids in a swine model of coronary artery spasm.
Topics: Animals; Arteriosclerosis; Body Weight; Cholesterol; Coronary Vasospasm; Disease Models, Animal; Epo | 1985 |
Airway responsiveness to inhaled antigen, histamine, and methacholine in inbred, ragweed-sensitized dogs.
Topics: Animals; Asthma; Bronchial Provocation Tests; Disease Models, Animal; Dogs; Female; Histamine; Immun | 1985 |
Effect of atropine on the hyperresponsiveness of ragweed-sensitized canine tracheal smooth muscle.
Topics: Animals; Asthma; Atropine; Bronchial Spasm; Disease Models, Animal; Dogs; Dose-Response Relationship | 1986 |
Coronary artery spasm induced in miniature swine: angiographic evidence and relation to coronary atherosclerosis.
Topics: Animals; Body Weight; Cholesterol; Cholesterol, HDL; Coronary Disease; Coronary Vasospasm; Coronary | 1985 |
Hypersensitivtiy responses in monkeys. VI. P-K, histamine, 48-80 responses after challenges with heterologous antigen or the other agents.
Topics: Animals; Antigen-Antibody Reactions; Antigens, Heterophile; Ascaris; Desensitization, Immunologic; D | 1973 |
Simple method for quantitation of enhanced vascular permeability.
Topics: Animals; Arthus Reaction; Azo Compounds; Bradykinin; Burns; Capillary Permeability; Disease Models, | 1970 |
[Studies on the mechanism of the therapeutic and toxic action of the horse chestnut saponin aescin].
Topics: Animals; Arthritis; Arthus Reaction; Bradykinin; Capillary Permeability; Carrageenan; Depression, Ch | 1970 |
Histamine metabolism in experimental silicosis. II. In vivo experiments in guinea pigs.
Topics: Amine Oxidase (Copper-Containing); Animals; Carboxy-Lyases; Collagen; Disease Models, Animal; Guinea | 1971 |
[Experimental asthma in guinea pigs and autonomic mediators].
Topics: Animals; Asthma; Atropine; Autonomic Agents; Cyclic AMP; Disease Models, Animal; Guinea Pigs; Hexame | 1972 |
immunoglobulin and histamine-sensitivity response of mice to live Bordetella pertussis.
Topics: Animals; Bordetella pertussis; Disease Models, Animal; Histamine; Immunodiffusion; Immunoelectrophor | 1973 |
[Effect of arpenal on pulmonary hypertension in experimental bronchospasm].
Topics: Animals; Blood Pressure; Bronchi; Bronchial Spasm; Cats; Diphenylacetic Acids; Disease Models, Anima | 1970 |
The vascular mechanism of intestinal protein exudation.
Topics: Acetylcholine; Animals; Blood Flow Velocity; Blood Proteins; Capillary Permeability; Catecholamines; | 1974 |
Studies in experimental eosinophilia. X. Dissociation of histamine-induced vascular eosinophilia and antigen-induced tissue eosinophilia.
Topics: Age Factors; Animals; Blood Cell Count; Cell Count; Disease Models, Animal; Eosinophilia; Eosinophil | 1973 |
[Significance of experimental ulcers in the screening of antiulcer drugs].
Topics: Acetates; Adrenal Cortex Hormones; Animals; Disease Models, Animal; Drug Evaluation, Preclinical; Du | 1973 |
Biogenic amine concentrations in traumatized spinal cords of cats. Effect of drug therapy.
Topics: Aminocaproates; Animals; Biogenic Amines; Cats; Disease Models, Animal; Dopamine; Female; Histamine; | 1974 |
Acute airway obstruction in rhesus monkeys induced by pharmacologic and immunologic stimuli.
Topics: Aerosols; Airway Obstruction; Animals; Antigens; Ascaris; Asthma; Disease Models, Animal; Histamine; | 1974 |
[Studies on the etiology of stress ulcers].
Topics: Animals; Disease Models, Animal; Duodenum; Female; Gastric Acidity Determination; Gastric Juice; Gas | 1972 |
A model for rat paw edema. I. Fitness of the model to some types of edema.
Topics: Acetates; Animals; Bradykinin; Carrageenan; Coloring Agents; Dextrans; Disease Models, Animal; Edema | 1970 |
Enhancement of inflammation and histamine formation by actinomycin D.
Topics: Animals; Carboxy-Lyases; Dactinomycin; Disease Models, Animal; Endotoxins; Female; Histamine; Inflam | 1969 |
Medical and surgical vagotomy.
Topics: Adult; Aged; Animals; Atropine; Disease Models, Animal; Dogs; Duodenal Ulcer; Female; Gastric Acidit | 1969 |
Gastric secretion after pentagastrin and histamine in the basal secreting ferret.
Topics: Animals; Carnivora; Disease Models, Animal; Fistula; Gastric Juice; Gastric Mucosa; Gastrins; Histam | 1970 |
Mucosal susceptibility in peptic ulceration; a method for testing.
Topics: Animals; Disease Models, Animal; Female; Gastric Juice; Gastric Mucosa; Guinea Pigs; Histamine; Hydr | 1970 |
Bronchoconstriction and apnea in canine anaphylaxis: possible role of histamine and plasma kinins.
Topics: Anaphylaxis; Animals; Blood Pressure; Bradykinin; Bronchial Spasm; Disease Models, Animal; Dogs; Fem | 1971 |
Posterior gastropexy (Hill) in the treatment of reflux esophagitis. An experimental study in the dog.
Topics: Animals; Disease Models, Animal; Dogs; Esophagitis, Peptic; Esophagogastric Junction; Esophagoscopy; | 1971 |