histamine has been researched along with Crohn Disease in 20 studies
Crohn Disease: A chronic transmural inflammation that may involve any part of the DIGESTIVE TRACT from MOUTH to ANUS, mostly found in the ILEUM, the CECUM, and the COLON. In Crohn disease, the inflammation, extending through the intestinal wall from the MUCOSA to the serosa, is characteristically asymmetric and segmental. Epithelioid GRANULOMAS may be seen in some patients.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of histamine-2 receptor antagonists (H2RAs) use causing inflammatory bowel diseases (IBD) has been reported in few isolated observational studies; however, pooled estimation of IBD risk has not been done." | 9.22 | Use of histamine-2 receptor antagonists and risk of inflammatory bowel diseases: A systematic review and meta-analysis of observational studies. ( Chandran, VP; D'sa, FF; Fernandes, EZ; Kesarkar, SV; Kunhikatta, V; Nair, S; Rashid, M; Swaminathan, L; Thunga, G, 2022) |
| "The effect of histamine-2 receptor antagonists (H2RAs) use causing inflammatory bowel diseases (IBD) has been reported in few isolated observational studies; however, pooled estimation of IBD risk has not been done." | 5.22 | Use of histamine-2 receptor antagonists and risk of inflammatory bowel diseases: A systematic review and meta-analysis of observational studies. ( Chandran, VP; D'sa, FF; Fernandes, EZ; Kesarkar, SV; Kunhikatta, V; Nair, S; Rashid, M; Swaminathan, L; Thunga, G, 2022) |
| " Therefore, tissue particles from normal subjects and from patients suffering from different diseases (Crohn's disease, ulcerative colitis, intestinal polyps) obtained at routine coloscopy were exposed to either Hanks or anti-IgE solution to determine the spontaneous or the anti-IgE-induced histamine release, expressed as the percentage of the total histamine content of the biopsy." | 3.67 | Histamine release from human colonic mucosa in response to anti-IgE. ( Baenkler, HW; Hörauf, AM; Matek, M; Raithel, M, 1989) |
| "Crohn disease is considered a consequence of inappropriate upregulation of immune reactions evoked by the intestinal microflora or luminal antigens." | 2.70 | Increased levels of specific leukocyte- and platelet-derived substances during normal anti-tetanus antibody synthesis in patients with inactive Crohn disease. ( Brünner, N; Holten-Andersen, M; Mortensen, T; Nielsen, HJ; Rask-Madsen, J; Sørensen, S, 2001) |
| "In the allergic bronchial asthma model using HDC-KO mice it was found that histamine positively controls eosinophilia, but not bronchial hypersensitivity." | 2.46 | Histamine synthesis and lessons learned from histidine decarboxylase deficient mice. ( Ohtsu, H, 2010) |
| "Histamine is a key immunoregulatory mediator in immediate-type hypersensitivity reactions and chronic inflammatory responses, in particular histamine suppresses proinflammatory responses to bacterial ligands, through histamine receptor 2 (H2R)." | 1.43 | Histamine Receptor 2 is Required to Suppress Innate Immune Responses to Bacterial Ligands in Patients with Inflammatory Bowel Disease. ( Akdis, CA; Ferstl, R; Frei, R; Groeger, D; Jutel, M; Konieczna, P; OʼMahony, L; Perez, NR; Schiavi, E; Smolinska, S, 2016) |
| "Histamine pretreatment of non-IBD control tissues reduced anti-IgE responses to levels seen in IBD colon but had no effect in small intestine." | 1.30 | Mast cell mediated ion transport in intestine from patients with and without inflammatory bowel disease. ( Crowe, SE; Luthra, GK; Perdue, MH, 1997) |
| "Histamine responses were blocked by the H1 antagonist mepyramine but were not altered by a diamine oxidase inhibitor." | 1.29 | Altered small intestinal smooth muscle function in Crohn's disease. ( Collins, SM; Huizinga, JD; Riddell, RH; Vermillion, DL, 1993) |
| "than in those with Crohn's disease and a control group." | 1.26 | Skin reactivity and phagocytic function of neutrophil leucocytes in Crohn's disease and ulcerative colitis. ( Juhlin, L; Krause, U; Michaëlsson, G, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (30.00) | 18.7374 |
| 1990's | 5 (25.00) | 18.2507 |
| 2000's | 3 (15.00) | 29.6817 |
| 2010's | 4 (20.00) | 24.3611 |
| 2020's | 2 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| D'sa, FF | 1 |
| Fernandes, EZ | 1 |
| Kesarkar, SV | 1 |
| Swaminathan, L | 1 |
| Kunhikatta, V | 1 |
| Rashid, M | 1 |
| Thunga, G | 1 |
| Chandran, VP | 1 |
| Nair, S | 1 |
| Sbeih, N | 1 |
| Bourguiba, R | 1 |
| Hoyeau-Idrissi, N | 1 |
| Launay, JM | 1 |
| Callebert, J | 1 |
| Canioni, D | 1 |
| Sokol, H | 1 |
| Hentgen, V | 1 |
| Grateau, G | 1 |
| Hermine, O | 1 |
| Georgin-Lavialle, S | 1 |
| Hagel, AF | 1 |
| de Rossi, T | 1 |
| Konturek, PC | 1 |
| Albrecht, H | 1 |
| Walker, S | 1 |
| Hahn, EG | 3 |
| Raithel, M | 4 |
| Smolinska, S | 1 |
| Groeger, D | 1 |
| Perez, NR | 1 |
| Schiavi, E | 1 |
| Ferstl, R | 1 |
| Frei, R | 1 |
| Konieczna, P | 1 |
| Akdis, CA | 1 |
| Jutel, M | 1 |
| OʼMahony, L | 1 |
| Nägel, A | 1 |
| Zopf, Y | 1 |
| deRossi, T | 1 |
| Stengel, Ch | 1 |
| Hagel, A | 1 |
| Kressel, J | 1 |
| Konturek, P | 1 |
| Ohtsu, H | 1 |
| TALLARIGO, A | 1 |
| CACUDI, G | 1 |
| Fogel, W | 1 |
| Lewiński, A | 1 |
| Jochem, J | 1 |
| Doldi, K | 1 |
| Manger, B | 1 |
| Koch, B | 1 |
| Riemann, J | 1 |
| Hermanek, P | 1 |
| Kalden, JR | 1 |
| Matek, M | 2 |
| Baenkler, HW | 3 |
| Jorde, W | 1 |
| Wantke, F | 1 |
| Götz, M | 1 |
| Jarisch, R | 1 |
| Araki, Y | 1 |
| Kakegawa, T | 1 |
| Stadil, F | 1 |
| Vermillion, DL | 1 |
| Huizinga, JD | 1 |
| Riddell, RH | 1 |
| Collins, SM | 1 |
| Crowe, SE | 1 |
| Luthra, GK | 1 |
| Perdue, MH | 1 |
| Nielsen, HJ | 1 |
| Mortensen, T | 1 |
| Holten-Andersen, M | 1 |
| Brünner, N | 1 |
| Sørensen, S | 1 |
| Rask-Madsen, J | 1 |
| Kuiarov, AV | 1 |
| Vorob'ev, AA | 1 |
| Nesvizhskiĭ, IuV | 1 |
| Krause, U | 1 |
| Michaëlsson, G | 1 |
| Juhlin, L | 1 |
| Hörauf, AM | 1 |
| Lux, G | 1 |
| Günthner, R | 1 |
| Kohlhäufl, M | 1 |
| Matek, W | 1 |
| Novis, BH | 1 |
| Bank, S | 1 |
| Marks, IN | 1 |
4 reviews available for histamine and Crohn Disease
| Article | Year |
|---|---|
Use of histamine-2 receptor antagonists and risk of inflammatory bowel diseases: A systematic review and meta-analysis of observational studies.
Topics: Adult; Child; Colitis, Ulcerative; Crohn Disease; Histamine; Histamine H2 Antagonists; Humans; Infla | 2022 |
Histamine synthesis and lessons learned from histidine decarboxylase deficient mice.
Topics: Anaphylaxis; Animals; Asthma; Atherosclerosis; Crohn Disease; Epigenesis, Genetic; Gene Expression R | 2010 |
Histamine in idiopathic inflammatory bowel diseases--not a standby player.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cimetidine; Crohn Disease; Histamine; Histamine An | 2005 |
[Possibility of participation of bacterial factor in the correction of histamine metabolism in the body].
Topics: Adult; Amine Oxidase (Copper-Containing); Animals; Antigens, Bacterial; Bacteria; Basophils; Birds; | 2000 |
2 trials available for histamine and Crohn Disease
| Article | Year |
|---|---|
Plasma histamine levels (H) during adjunctive H1-receptor antagonist treatment with loratadine in patients with active inflammatory bowel disease (IBD).
Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Crohn Diseas | 2010 |
Increased levels of specific leukocyte- and platelet-derived substances during normal anti-tetanus antibody synthesis in patients with inactive Crohn disease.
Topics: Adult; Aged; Antibodies, Bacterial; C-Reactive Protein; Clostridium tetani; Crohn Disease; Enzyme-Li | 2001 |
14 other studies available for histamine and Crohn Disease
| Article | Year |
|---|---|
Histamine elevation in familial Mediterranean fever: A study from the Juvenile Inflammatory Rheumatism cohort.
Topics: Adult; Colchicine; Crohn Disease; Familial Mediterranean Fever; Histamine; Humans; Mast Cells; Masto | 2023 |
Plasma histamine and tumour necrosis factor-alpha levels in Crohn's disease and ulcerative colitis at various stages of disease.
Topics: Adult; Aged; Colitis, Ulcerative; Crohn Disease; Disease Progression; Female; Histamine; Humans; Int | 2015 |
Histamine Receptor 2 is Required to Suppress Innate Immune Responses to Bacterial Ligands in Patients with Inflammatory Bowel Disease.
Topics: Adult; Animals; Case-Control Studies; Cells, Cultured; Colitis, Ulcerative; Crohn Disease; Cytokines | 2016 |
[Histamine & lymphatic stasis in the pathogenesis of experimental regional enteritis].
Topics: Crohn Disease; Histamine; Histamine Agents; Ileitis; Lymphatic Vessels | 1958 |
Spontaneous suppressor cell activity in the peripheral blood of patients with malignant and chronic inflammatory bowel diseases.
Topics: Adenocarcinoma; Adult; Antigens, Surface; Cells, Cultured; Cimetidine; Colonic Neoplasms; Crohn Dise | 1984 |
Mucosal histamine content and histamine secretion in Crohn's disease, ulcerative colitis and allergic enteropathy.
Topics: Biopsy; Colitis, Ulcerative; Crohn Disease; Female; Histamine; Histamine Release; Humans; Hypersensi | 1995 |
Dietary treatment of Crohn's disease.
Topics: Amine Oxidase (Copper-Containing); Crohn Disease; Histamine; Humans | 1994 |
Mast cells and histamine release in Crohn's disease.
Topics: Antibodies, Anti-Idiotypic; Crohn Disease; Histamine; Humans; Mast Cells | 1993 |
Altered small intestinal smooth muscle function in Crohn's disease.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Carbachol; Crohn Disease; Dose-Response Relationship, Dr | 1993 |
Mast cell mediated ion transport in intestine from patients with and without inflammatory bowel disease.
Topics: Animals; Antibodies, Anti-Idiotypic; Colforsin; Colitis, Ulcerative; Crohn Disease; Histamine; Hista | 1997 |
Skin reactivity and phagocytic function of neutrophil leucocytes in Crohn's disease and ulcerative colitis.
Topics: Adolescent; Adult; Aged; Antigens, Bacterial; Bradykinin; Colitis, Ulcerative; Crohn Disease; Female | 1978 |
Histamine release from human colonic mucosa in response to anti-IgE.
Topics: Antibodies, Anti-Idiotypic; Colitis, Ulcerative; Colon; Crohn Disease; Histamine; Histamine Release; | 1989 |
Biopsy histamine in ulcerative colitis and Crohn's disease.
Topics: Adult; Biopsy; Colitis, Ulcerative; Colon; Crohn Disease; Female; Histamine; Humans; Intestinal Muco | 1987 |
Gastric acid secretion and intestinal malabsorption.
Topics: Adolescent; Adult; Blind Loop Syndrome; Celiac Disease; Child; Crohn Disease; Duodenal Ulcer; Female | 1973 |