Page last updated: 2024-10-18

histamine and Colitis, Mucous

histamine has been researched along with Colitis, Mucous in 21 studies

Research Excerpts

ExcerptRelevanceReference
"We previously showed that mucosal biopsy supernatants from irritable bowel syndrome patients activated neurons despite low concentrations of tryptase, histamine, and serotonin which individually would not cause spike discharge."7.85Tryptase potentiates enteric nerve activation by histamine and serotonin: Relevance for the effects of mucosal biopsy supernatants from irritable bowel syndrome patients. ( Annahazi, A; Ceyhan, GO; Demir, IE; Krueger, D; Michel, K; Ostertag, D; Schemann, M; Zeller, F, 2017)
" We showed that decreasing intake of fermentable carbohydrates improved abdominal pain in patients with IBS, and this was accompanied by changes in the gut microbiota and decreased urinary histamine concentrations."4.12Histamine production by the gut microbiota induces visceral hyperalgesia through histamine 4 receptor signaling in mice. ( Baerg, L; Bai, X; Bercik, P; Beyak, M; Caminero, A; Collins, SM; De Palma, G; Jaramillo-Polanco, J; Jimenez-Vargas, N; Lomax, AE; Lopez-Lopez, C; Lu, J; Madsen, K; Manzar, A; Pigrau, M; Pinto-Sanchez, MI; Pujo, J; Rabbia, V; Reed, DE; Sessenwein, J; Shimbori, C; Surette, MG; Vanner, SJ; Verdu, EF; Yu, Y; Zhang, Y, 2022)
"The article presents an analysis of the literature on food intolerance (FS) associated with the presence in the diet of fermentable oligodimosaccharides and polyols FODMAP (fermentable oligosaccharides, disaccharides, monosaccharides and polyols), histamine and food additives."4.12[Food intolerances and the small intestine]. ( Parfenov, AI, 2022)
"The aim of this study was to investigate the efficacy and safety of the novel complex drug, consisting of released-active form of antibodies to S-100 protein, tumor necrosis factor-α and histamine, (Kolofort) under outpatient conditions in patients with functional dyspepsia (FD), irritable bowel syndrome (IBS), and FD-IBS overlap."3.91Pathogenetic approach to the treatment of functional disorders of the gastrointestinal tract and their intersection: results of the Russian observation retrospective program COMFORT. ( Epstein, OI; Glazunov, AB; Ivashkin, VT; Poluektova, EA; Putilovskiy, MA, 2019)
"We previously showed that mucosal biopsy supernatants from irritable bowel syndrome patients activated neurons despite low concentrations of tryptase, histamine, and serotonin which individually would not cause spike discharge."3.85Tryptase potentiates enteric nerve activation by histamine and serotonin: Relevance for the effects of mucosal biopsy supernatants from irritable bowel syndrome patients. ( Annahazi, A; Ceyhan, GO; Demir, IE; Krueger, D; Michel, K; Ostertag, D; Schemann, M; Zeller, F, 2017)
" The dose-response curves show an analytical range between 5 and 200 nM of histamine, corresponding to physiologically normal conditions while higher concentrations correlate with disease."1.56Towards a catheter-based impedimetric sensor for the assessment of intestinal histamine levels in IBS patients. ( Cornelis, P; Doll, T; Peeters, M; Putzeys, T; Tack, J; Troost, F; Van de Cauter, L; Verhaert, N; Wackers, G; Wagner, P; Wübbenhorst, M, 2020)
"The term "food allergy" is widely misused for all sorts of symptoms and diseases caused by food."1.35[Food allergy, food intolerance or functional disorder?]. ( Wüthrich, B, 2009)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (19.05)29.6817
2010's6 (28.57)24.3611
2020's11 (52.38)2.80

Authors

AuthorsStudies
Fukudo, S1
Kano, M1
Sato, Y1
Muratsubaki, T1
Kanazawa, M1
Tashiro, M1
Yanai, K1
Hasler, WL1
Grabauskas, G1
Singh, P1
Owyang, C1
De Palma, G2
Shimbori, C1
Reed, DE2
Yu, Y1
Rabbia, V1
Lu, J1
Jimenez-Vargas, N1
Sessenwein, J1
Lopez-Lopez, C1
Pigrau, M1
Jaramillo-Polanco, J1
Zhang, Y1
Baerg, L1
Manzar, A1
Pujo, J1
Bai, X1
Pinto-Sanchez, MI1
Caminero, A1
Madsen, K2
Surette, MG1
Beyak, M1
Lomax, AE1
Verdu, EF1
Collins, SM1
Vanner, SJ1
Bercik, P2
Ray, K1
Keszthelyi, D1
Parfenov, AI1
Ivashkin, VT1
Poluektova, EA1
Glazunov, AB1
Putilovskiy, MA1
Epstein, OI1
Wackers, G1
Putzeys, T1
Peeters, M1
Van de Cauter, L1
Cornelis, P1
Wübbenhorst, M1
Tack, J1
Troost, F1
Verhaert, N1
Doll, T1
Wagner, P1
Uranga, JA1
Martínez, V1
Abalo, R1
Perna, E1
Aguilera-Lizarraga, J1
Florens, MV1
Jain, P1
Theofanous, SA1
Hanning, N1
De Man, JG1
Berg, M1
De Winter, B1
Alpizar, YA1
Talavera, K1
Vanden Berghe, P1
Wouters, M1
Boeckxstaens, G1
Brizuela, M1
Castro, J1
Harrington, AM1
Brierley, SM1
Ostertag, D1
Annahazi, A1
Krueger, D1
Michel, K2
Demir, IE1
Ceyhan, GO1
Zeller, F2
Schemann, M2
Potter, MDE1
Goodsall, TM1
Walker, MM1
Talley, NJ1
Böhn, L1
Störsrud, S1
Törnblom, H1
Bengtsson, U1
Simrén, M1
Mearin, F1
Rey, E1
Balboa, A1
McIntosh, K1
Schneider, T1
Dang, F1
Keshteli, AH1
Vanner, S1
Stoianov, SG1
Penchev, PI1
Gerova, VA1
Tsenova, VG1
Wüthrich, B1
Buhner, S1
Li, Q1
Vignali, S1
Barbara, G2
De Giorgio, R2
Stanghellini, V2
Cremon, C2
Langer, R1
Daniel, H1
Carini, G1
Wang, B1
Vasina, V1
Cogliandro, RF1
Grundy, D1
Tonini, M1
De Ponti, F1
Corinaldesi, R1
Wood, JD1

Clinical Trials (6)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparison of Microbiota and Quality of Life for a Low FODMAPs Versus Standard Dietary Advice in Patients With Irritable Bowel Syndrome[NCT02902926]120 participants (Anticipated)Interventional2016-09-30Recruiting
The Effect of Prebiotics on the Microbiome in Irritable Bowel Syndrome Patients: The Diet and Microbiome Study[NCT01829932]30 participants (Actual)Interventional2013-04-30Completed
Molecular Phenotyping of IBS Subtypes[NCT03653689]110 participants (Actual)Interventional2018-09-10Completed
A Study Evaluating the Effects of Low and High FODMAP Diets on Mucosal Protease Nerve Interactions in IBS Patients[NCT03221790]20 participants (Anticipated)Interventional2017-11-01Not yet recruiting
Investigating Serotonin Signalling in IBD Patients[NCT01650311]60 participants (Anticipated)Observational2012-07-31Recruiting
A Double-Blind, Randomized, Placebo-Controlled Multicenter Study to Assess the Safety and Efficacy of AST-120 in Patients With Non-Constipating Irritable Bowel Syndrome[NCT00583128]Phase 2117 participants (Actual)Interventional2007-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for histamine and Colitis, Mucous

ArticleYear
Histamine Neuroimaging in Stress-Related Disorders.
    Current topics in behavioral neurosciences, 2022, Volume: 59

    Topics: Animals; Brain; Depressive Disorder, Major; Doxepin; Female; Histamine; Humans; Hypnotics and Sedati

2022
Mast cell mediation of visceral sensation and permeability in irritable bowel syndrome.
    Neurogastroenterology and motility, 2022, Volume: 34, Issue:7

    Topics: Diarrhea; Histamine; Humans; Intestinal Mucosa; Irritable Bowel Syndrome; Mast Cells; Peptide Hydrol

2022
Mast Cell Regulation and Irritable Bowel Syndrome: Effects of Food Components with Potential Nutraceutical Use.
    Molecules (Basel, Switzerland), 2020, Sep-20, Volume: 25, Issue:18

    Topics: Abdominal Pain; Amino Acids; Animals; Cannabidiol; Constipation; Diarrhea; Dietary Supplements; Eati

2020
Pruritogenic mechanisms and gut sensation: putting the "irritant" into irritable bowel syndrome.
    American journal of physiology. Gastrointestinal and liver physiology, 2021, 06-01, Volume: 320, Issue:6

    Topics: Colon; Histamine; Humans; Hyperalgesia; Irritable Bowel Syndrome; Mast Cells; Visceral Pain

2021
[Functional and motor gastrointestinal disorders].
    Gastroenterologia y hepatologia, 2015, Volume: 38 Suppl 1

    Topics: Antidepressive Agents; Biomarkers; Constipation; Diarrhea; Dietary Carbohydrates; Dietary Fiber; Div

2015

Trials

1 trial available for histamine and Colitis, Mucous

ArticleYear
FODMAPs alter symptoms and the metabolome of patients with IBS: a randomised controlled trial.
    Gut, 2017, Volume: 66, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Breath Tests; Dicarboxylic Acids; Diet; Feces; Female; Gastrointesti

2017
FODMAPs alter symptoms and the metabolome of patients with IBS: a randomised controlled trial.
    Gut, 2017, Volume: 66, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Breath Tests; Dicarboxylic Acids; Diet; Feces; Female; Gastrointesti

2017
FODMAPs alter symptoms and the metabolome of patients with IBS: a randomised controlled trial.
    Gut, 2017, Volume: 66, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Breath Tests; Dicarboxylic Acids; Diet; Feces; Female; Gastrointesti

2017
FODMAPs alter symptoms and the metabolome of patients with IBS: a randomised controlled trial.
    Gut, 2017, Volume: 66, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Breath Tests; Dicarboxylic Acids; Diet; Feces; Female; Gastrointesti

2017
FODMAPs alter symptoms and the metabolome of patients with IBS: a randomised controlled trial.
    Gut, 2017, Volume: 66, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Breath Tests; Dicarboxylic Acids; Diet; Feces; Female; Gastrointesti

2017
FODMAPs alter symptoms and the metabolome of patients with IBS: a randomised controlled trial.
    Gut, 2017, Volume: 66, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Breath Tests; Dicarboxylic Acids; Diet; Feces; Female; Gastrointesti

2017
FODMAPs alter symptoms and the metabolome of patients with IBS: a randomised controlled trial.
    Gut, 2017, Volume: 66, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Breath Tests; Dicarboxylic Acids; Diet; Feces; Female; Gastrointesti

2017
FODMAPs alter symptoms and the metabolome of patients with IBS: a randomised controlled trial.
    Gut, 2017, Volume: 66, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Breath Tests; Dicarboxylic Acids; Diet; Feces; Female; Gastrointesti

2017
FODMAPs alter symptoms and the metabolome of patients with IBS: a randomised controlled trial.
    Gut, 2017, Volume: 66, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Breath Tests; Dicarboxylic Acids; Diet; Feces; Female; Gastrointesti

2017

Other Studies

15 other studies available for histamine and Colitis, Mucous

ArticleYear
Histamine production by the gut microbiota induces visceral hyperalgesia through histamine 4 receptor signaling in mice.
    Science translational medicine, 2022, 07-27, Volume: 14, Issue:655

    Topics: Abdominal Pain; Animals; Carbohydrates; Gastrointestinal Microbiome; Histamine; Hyperalgesia; Irrita

2022
Bacterial histamine and abdominal pain in IBS.
    Nature reviews. Gastroenterology & hepatology, 2022, Volume: 19, Issue:10

    Topics: Abdominal Pain; Histamine; Humans; Irritable Bowel Syndrome

2022
Histamine-Producing Bacteria: The Missing Link in Irritable Bowel Syndrome?
    Gastroenterology, 2023, Volume: 164, Issue:1

    Topics: Bacteria; Histamine; Humans; Irritable Bowel Syndrome

2023
[Food intolerances and the small intestine].
    Terapevticheskii arkhiv, 2022, Feb-15, Volume: 94, Issue:2

    Topics: Disaccharides; Duodenum; Fermentation; Food Additives; Food Intolerance; Histamine; Humans; Irritabl

2022
Pathogenetic approach to the treatment of functional disorders of the gastrointestinal tract and their intersection: results of the Russian observation retrospective program COMFORT.
    BMC gastroenterology, 2019, Dec-31, Volume: 20, Issue:1

    Topics: Adult; Ambulatory Care; Antibodies; Drug Combinations; Dyspepsia; Female; Health Surveys; Histamine;

2019
Towards a catheter-based impedimetric sensor for the assessment of intestinal histamine levels in IBS patients.
    Biosensors & bioelectronics, 2020, Jun-15, Volume: 158

    Topics: Biomimetics; Biosensing Techniques; Catheters; Dielectric Spectroscopy; Electric Impedance; Electrod

2020
Effect of resolvins on sensitisation of TRPV1 and visceral hypersensitivity in IBS.
    Gut, 2021, Volume: 70, Issue:7

    Topics: Adult; Animals; Capsaicin; Disease Models, Animal; Docosahexaenoic Acids; Eicosapentaenoic Acid; Ent

2021
Tryptase potentiates enteric nerve activation by histamine and serotonin: Relevance for the effects of mucosal biopsy supernatants from irritable bowel syndrome patients.
    Neurogastroenterology and motility, 2017, Volume: 29, Issue:9

    Topics: Adult; Aged; Biopsy; Enteric Nervous System; Female; Histamine; Humans; Intestinal Mucosa; Irritable

2017
Dual histamine blockade for the treatment of adult functional dyspepsia: a single centre experience.
    Gut, 2020, Volume: 69, Issue:5

    Topics: Abdominal Pain; Adult; Dyspepsia; Gastritis; Histamine; Humans; Irritable Bowel Syndrome

2020
Self-reported food-related gastrointestinal symptoms in IBS are common and associated with more severe symptoms and reduced quality of life.
    The American journal of gastroenterology, 2013, Volume: 108, Issue:5

    Topics: Adult; Aged; Anxiety; Biogenic Amines; Depression; Diet; Dietary Carbohydrates; Dietary Fats; Eating

2013
Histamine, 5-hydroxytriptamine, collagen, mast cells and Ig-secreting cells in the small bowel disorders with diarrhea.
    Journal of gastrointestinal and liver diseases : JGLD, 2008, Volume: 17, Issue:4

    Topics: Adult; Antibody-Producing Cells; Celiac Disease; Chronic Disease; Diarrhea; Enteritis; Female; Hista

2008
[Food allergy, food intolerance or functional disorder?].
    Praxis, 2009, Apr-01, Volume: 98, Issue:7

    Topics: Adult; Child; Child, Preschool; Cross Reactions; Diagnosis, Differential; Food Hypersensitivity; Gas

2009
Activation of human enteric neurons by supernatants of colonic biopsy specimens from patients with irritable bowel syndrome.
    Gastroenterology, 2009, Volume: 137, Issue:4

    Topics: Action Potentials; Adult; Aged; Biopsy; Case-Control Studies; Cell Extracts; Colon; Constipation; Di

2009
Intestinal serotonin release, sensory neuron activation, and abdominal pain in irritable bowel syndrome.
    The American journal of gastroenterology, 2011, Volume: 106, Issue:7

    Topics: Abdominal Pain; Adult; Animals; Cell Count; Enterochromaffin Cells; Female; Histamine; Humans; Intes

2011
Histamine, mast cells, and the enteric nervous system in the irritable bowel syndrome, enteritis, and food allergies.
    Gut, 2006, Volume: 55, Issue:4

    Topics: Enteritis; Food Hypersensitivity; Histamine; Humans; Ileum; Intestinal Mucosa; Intestine, Large; Int

2006