histamine has been researched along with Asthma, Bronchial in 2169 studies
Excerpt | Relevance | Reference |
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"Low-dose salbutamol suppresses airway responsiveness to histamine but not methacholine in subjects with asthma." | 9.17 | Low-dose salbutamol suppresses airway responsiveness to histamine but not methacholine in subjects with asthma. ( Aizawa, H; Fukuyama, S; Inoue, H; Komori, M; Koto, H; Matsumoto, K; Takata, S; Yoshida, M, 2013) |
"In this randomized controlled, double blind study, 30 asthmatics were challenged with histamine until forced expiratory volume in 1s (FEV(1)) fell with > or =20%." | 9.12 | Effects of long-acting bronchodilators and placebo on histamine-induced asthma symptoms and mild bronchusobstruction. ( De Peuter, S; Lemaigre, V; Smets, A; Van den Bergh, O; Verleden, GM, 2006) |
"Therefore, we compared the effects of beclomethasone dipropionate (BDP) on the degree of BHR to inhaled histamine and NKA in a double-blind, controlled, cross-over study of asthmatic patients." | 9.12 | Beclomethasone dipropionate attenuates airways hyperresponsiveness to neurokinin A and histamine in asthma. ( Arcidiacono, G; Ciamarra, I; Crimi, N; Polosa, R; Prosperini, G, 2006) |
"To study the effect of montelukast (10 mg/day) on histamine and cysteinyl leukotriene release from basophils taken from 12 mild atopic asthmatic patients who took the drug for 4 weeks." | 9.11 | Effect of montelukast on basophil releasability in patients with asthma. ( Fireman, E; Kivity, S; Sade, K; Schwartz, Y, 2005) |
" We investigated the early effects of inhaled fluticasone propionate (FP) therapy on AR in 3 consecutive double-blind, randomized, placebo-controlled crossover studies in steroid-naive subjects with mild asthma." | 9.10 | Rapid effect of inhaled fluticasone propionate on airway responsiveness to adenosine 5'-monophosphate in mild asthma. ( Allenby, MI; Jensen, MW; Ketchell, RI; Lumley, P; O'connor, BJ; Wright, AM, 2002) |
"The underlying mechanisms of bronchoconstriction in aspirin-intolerant asthmatics (AIAs) are still unknown, but the hypothesis of an altered metabolism of arachidonic acid is generally accepted." | 9.09 | Dynamics of eicosanoids in peripheral blood cells during bronchial provocation in aspirin-intolerant asthmatics. ( Baenkler, HW; Göde, UC; Schäfer, D; Schmid, M, 1999) |
" We undertook a double-blind, randomized, placebo-controlled, cross-over study to investigate the effects of a single dose of formoterol inhaled via Turbuhaler (12 micrograms) and of albuterol inhaled via Turbuhaler (200 micrograms) on airway responsiveness to AMP and histamine in 16 subjects with mild atopic asthma." | 9.09 | Differential effect of formoterol on adenosine monophosphate and histamine reactivity in asthma. ( Barnes, PJ; Nightingale, JA; Rogers, DF, 1999) |
"We sought to test the efficacy of oral antifungal treatment for Trichophyton-induced asthma by using fluconazole in a placebo-controlled trial." | 9.09 | Treatment of late-onset asthma with fluconazole. ( Hayden, ML; Jackson, S; Platts-Mills, TA; Ward, GW; Woodfolk, JA, 1999) |
"In a double blind, crossover study 14 asthmatic patients received pretreatment with oral L-arginine (50 mg/kg body weight) or placebo prior to histamine challenge." | 9.09 | Effect of oral L-arginine on airway hyperresponsiveness to histamine in asthma. ( de Gouw, HW; Sterk, PJ; Twiss, IM; Verbruggen, MB, 1999) |
"The purpose of our study was to evaluate the response of persons with mild asthma to inhaled allergen after ozone exposure conditions similar to those observed in urban areas of the United States." | 9.09 | Increased specific airway reactivity of persons with mild allergic asthma after 7.6 hours of exposure to 0.16 ppm ozone. ( Ball, B; Folinsbee, LJ; Horstman, D; Kehrl, HR; Peden, DB, 1999) |
" placebo in 15 mild asthmatic patients, selected by their response to a histamine challenge (decrease in FEV1 > 20% to less than 18 mg mL-1 of histamine [PC20])." | 9.09 | Lidocaine inhalation for local anaesthesia and attenuation of bronchial hyper-reactivity with least airway irritation. Effect of three different dose regimens. ( Beste, M; Groeben, H; Grosswendt, T; Peters, J; Silvanus, M, 2000) |
"We previously reported that inhaled acetaldehyde, a metabolite of ethanol and a main factor in alcohol-induced asthma, causes bronchoconstriction indirectly through endogenously released histamine in asthmatic subjects." | 9.08 | Repeated inhalation challenge with exogenous and endogenous histamine released by acetaldehyde inhalation in asthmatic patients. ( Bando, T; Fujimura, M; Kamio, Y; Matsuda, T; Myou, S; Nakatsumi, Y, 1995) |
"We examined the effect of procaterol, a beta 2-adrenoceptor agonist, on skin whealing responses to histamine, platelet-activating factor (PAF), substance P, or bradykinin in eight asthmatic children in a double-blind, randomized, cross-over study." | 9.08 | Effect of procaterol, a beta 2-adrenoceptor agonist, on skin whealing response caused by inflammatory mediators in asthmatic children. ( Arakawa, H; Maeda, S; Morikawa, A; Tokuyama, K, 1995) |
"Eleven atopic asthmatic subjects underwent two concentration-response studies, separated by 1 hour, with either inhaled histamine or bradykinin." | 9.08 | Cross refractoriness between bradykinin and hypertonic saline challenges in asthma. ( Holgate, ST; Howarth, PH; Makker, HK; Rajakulasingam, K, 1995) |
"Bradykinin is a potent vasoactive peptide which has been proposed as an important inflammatory mediator in asthma since it provokes potent bronchoconstriction in asthmatic subjects." | 9.08 | Effect of an inhaled neutral endopeptidase inhibitor, phosphoramidon, on baseline airway calibre and bronchial responsiveness to bradykinin in asthma. ( Crimi, N; Magrì, S; Mastruzzo, C; Mistretta, A; Polosa, R; Prosperini, G; Pulvirenti, G; Santonocito, G, 1995) |
"We evaluated the effect of inhaled indomethacin, a nonsteroidal antiinflammatory drug (NSAID), against bronchoconstriction induced by ultrasonically nebulized distilled water (UNDW) in children with asthma." | 9.08 | Inhaled indomethacin prevents bronchoconstrictive response to distilled water but not to histamine in children with asthma. ( Kuroume, T; Maeda, S; Mochizuki, H; Morikawa, A; Shigeta, M; Shimizu, T, 1995) |
"In study 1 the UNDW, AA, and histamine inhalation challenges were performed in 40 asthmatic children (26 boys, aged from 7 to 16 years; mean +/- SD, 11." | 9.08 | Relationship between ultrasonically nebulized distilled water-induced bronchoconstriction and acetic acid-induced cough in asthmatic children. ( Kuroume, T; Maeda, S; Mochizuki, H; Morikawa, A; Shimizu, T; Tokuyama, K, 1995) |
"Several studies have suggested that patients with bronchial asthma are more susceptible to the potential effects of nitrogen dioxide (NO2) than healthy subjects, with respect to airway responsiveness and lung function." | 9.08 | The effect of 1 ppm nitrogen dioxide on bronchoalveolar lavage cells and inflammatory mediators in normal and asthmatic subjects. ( Grimminger, F; Jörres, R; Magnussen, H; Nowak, D; Oldigs, M; Seeger, W, 1995) |
"To test the hypothesis that surfactant nebulization improves pulmonary function and reduces bronchial responsiveness to histamine, we studied 12 children with asthma." | 9.08 | Surfactant nebulization does not alter airflow obstruction and bronchial responsiveness to histamine in asthmatic children. ( Bos, H; Dorrepaal, C; Gerritsen, J; Koëter, GH; Oetomo, SB; van Aalderen, WM; van der Mark, TW, 1996) |
" Morning baseline values of urinary 9 alpha, 11 beta-PGF2 were measured in three groups--healthy volunteers (n = 9), patients with atopic asthma (n = 14), and aspirin-intolerant patients with asthma (n = 12)--and found to be very similar, 54 +/- 9, 62 +/- 6, and 71 +/- 15 ng/mmol creatinine, respectively (means +/- SEM)." | 9.08 | Increased urinary excretion of the prostaglandin D2 metabolite 9 alpha, 11 beta-prostaglandin F2 after aspirin challenge supports mast cell activation in aspirin-induced airway obstruction. ( Dahlén, B; Dahlén, SE; Kumlin, M; O'Sullivan, S, 1996) |
"When administered by inhalation, histamine provokes dose-related bronchoconstriction in asthmatic subjects mainly by a direct activation of histamine H1-receptors on airway smooth muscle." | 9.08 | Inhaled lysine acetylsalicylate (L-ASA) attenuates histamine-induced bronchoconstriction in asthma. ( Crimi, N; Magrì, S; Mastruzzo, C; Mistretta, A; Paolino, G; Polosa, R; Prosperini, G, 1996) |
"Clinical and epidemiologic studies suggest that ambient ozone exposure may increase the response of patients with asthma to inhaled allergen." | 9.08 | Allergen bronchoprovocation of patients with mild allergic asthma after ozone exposure. ( Ball, BA; Folinsbee, LJ; Kehrl, HR; Peden, DB, 1996) |
"In a randomized, double-blind, placebo controlled cross-over study we have investigated the effect of intravenous magnesium on airway calibre and airway reactivity to histamine in 20 subjects with mild to moderate asthma." | 9.08 | Effect of intravenous magnesium sulphate on airway calibre and airway reactivity to histamine in asthmatic subjects. ( Britton, J; Hill, JM, 1996) |
"To explore this further, the airway responsiveness to sodium metabisulphite (MBS), an indirect neural stimulus with similar characteristics to bradykinin, was compared in 18 mild steroid-naive asthmatic subjects with the airway responsiveness to histamine before and after allergen challenge with extracts of house dust mite, grass pollen, or cat." | 9.08 | Effect of allergen challenge on airway responsiveness to histamine and sodium metabisulphite in mild asthma. ( Coulby, LJ; Evans, DJ; O'Connor, BJ, 1996) |
" A study was performed to evaluate whether there are differences in the perception of histamine induced bronchoconstriction between anxious and non-anxious perceivers and whether anxious perception of bronchoconstriction can be predicted by higher levels of baseline anxiety." | 9.08 | Association of anxiety with perception of histamine induced bronchoconstriction in patients with asthma. ( Spinhoven, P; Sterk, PJ; Van der Does, AJ; van Peski-Oosterbaan, AS; Willems, LN, 1997) |
"We conclude that the severity of cold, as induced by experimental RV16 infection, is a determinant of the increase in airway hypersensitivity to histamine in patients with asthma." | 9.08 | Effect of experimental rhinovirus 16 colds on airway hyperresponsiveness to histamine and interleukin-8 in nasal lavage in asthmatic subjects in vivo. ( de Klerk, EP; Dick, EC; Grünberg, K; Hiemstra, PS; Smits, HH; Spaan, WJ; Sterk, PJ; Timmers, MC, 1997) |
"To measure the effects of a single inhaled nebulized dose of 180 mg magnesium sulphate on airway reactivity to a direct-acting bronchoconstrictor (histamine) and an indirect-acting bronchoconstrictor (adenosine monophosphate [AMP]) in asthmatic subjects." | 9.08 | Studies of the effects of inhaled magnesium on airway reactivity to histamine and adenosine monophosphate in asthmatic subjects. ( Britton, J; Hill, J; Lewis, S, 1997) |
" Mast cells play very important role in early phase of asthmatic reaction, releasing many proinflammatory mediators including histamine." | 9.08 | [The influence of heparin on histamine level in plasma during the early reaction phase of asthma]. ( Antczak-Marczak, M; Kuna, P, 1997) |
" We undertook two double-blind, randomized, crossover, placebo-controlled studies to investigate the effects of salmeterol and albuterol on airway responsiveness (AR) to AMP and histamine in patients with mild asthma." | 9.08 | Comparison of salmeterol and albuterol-induced bronchoprotection against adenosine monophosphate and histamine in mild asthma. ( Aikman, SL; Barnes, PJ; Harris, JG; Jensen, MW; O'Connor, BJ; Taylor, DA, 1997) |
"The aim of this study was to examine the inter-relationships between the different effects of deep breaths and histamine provocation on airway function in patients with bronchial asthma." | 9.08 | Excessive bronchoconstriction induced by histamine and effects of volume history in patients with bronchial asthma. ( Ang, SM; Lim, TK, 1997) |
"The efficacy of nedocromil sodium (NED) (8mg twice daily) in controlling the clinical symptoms of asthma (score symptoms), the pulmonary parameters (FEV1, FVC) and bronchial hyperreactivity to histamine was assessed." | 9.08 | [The effect of nedocromil sodium on the clinical course, ventilatory parameters and nonspecific bronchial hyperreactivity in patients with nonatopic bronchial asthma treated with beclomethasone dipropionate]. ( Grabski, W; Grzelewska-Rzymowska, I; Kroczyńska-Bednarek, J; Tymińska, K, 1997) |
"The aim of the study was to determine whether zileuton, an inhibitor of 5-lipoxygenase, attenuated bronchial hyperresponsiveness (BHR) in asthmatic subjects who had marked BHR during maintenance treatment with inhaled corticosteroids (ICS)." | 9.08 | Effects of single-dose zileuton on bronchial hyperresponsiveness in asthmatic patients treated with inhaled corticosteroids. ( Bootsma, GP; Dekhuijzen, PN; Festen, J; van den Berg, LR; van Herwaarden, CL; Wielders, PL, 1997) |
"Breathing pattern variability was determined in 10 asthmatic adolescents during repeated bronchial histamine and methacholine challenges (HiCh/MeCh)." | 9.08 | Breathing pattern variability during bronchial histamine and methacholine challenges in asthmatics. ( Gustafsson, PM; Strömberg, NO, 1996) |
"From bronchoprovocation studies and investigations of the acute effects of drugs that inhibit leukotrienes (LT), the hypothesis has emerged that leukotrienes are important mediators of airway obstruction and other symptoms in aspirin-intolerant asthma (AIA)." | 9.08 | Benefits from adding the 5-lipoxygenase inhibitor zileuton to conventional therapy in aspirin-intolerant asthmatics. ( Bochenek, G; Boodhoo, TI; Dahlén, B; Dahlén, SE; Dubé, LM; Kumlin, M; Mastalerz, L; Nizankowska, E; Pinis, G; Swanson, LJ; Szczeklik, A; Wright, S; Zetterström, O, 1998) |
"We investigated whether the deterioration in asthma control reported following cessation of theophylline was due to tolerance to theophylline." | 9.08 | The airway effects of stopping regular oral theophylline in patients with asthma. ( Bennett, JA; Pavord, ID; Tattersfield, AE; Thompson Coon, J; Wilding, PJ, 1998) |
"The increase in nasal symptoms in aspirin-sensitive patients with asthma after aspirin ingestion is associated with increases in nasal tryptase, histamine, and cysteinyl leukotriene levels." | 9.07 | Direct evidence for a role of the mast cell in the nasal response to aspirin in aspirin-sensitive asthma. ( Callery, JC; Cohn, J; Drazen, JM; Fischer, AR; Igarashi, Y; Kaliner, MA; Lilly, CM; Rosenberg, MA; Rubin, P; White, MV, 1994) |
"In order to examine the changes in bronchial hypersensitivity, histamine inhalation tests were evaluated in 27 asthmatic children who remitted." | 9.07 | [Bronchial hypersensitivity to histamine in asthmatic children longitudinal study from first visit to remitted state]. ( Adachi, Y; Ikarashi, T; Iwaya, M; Kayahara, M; Matsuno, M; Murakami, G; Onoue, Y; Takayanagi, M, 1994) |
"We performed a study of the action of chlorpheniramine, terfenadine, brompheniramine, cetirizine, cyproheptadine, clemastine, and astemizole compared with placebo on histamine-induced skin wheals and bronchoconstriction in a single group of patients with asthma." | 9.07 | The comparative actions and adverse effect profile of single doses of H1-receptor antihistamines in the airways and skin of subjects with asthma. ( Holgate, ST; Wood-Baker, R, 1993) |
"Neurokinin A (NKA) elicits a potent contractile effect in asthmatic airways." | 9.07 | Effect of oral terfenadine on bronchoconstrictor response to inhaled neurokinin A and histamine in asthmatic subjects. ( Crimi, N; Mistretta, A; Oliveri, R; Palemo, F; Polosa, R; Prosperini, G; Pulvirenti, G, 1993) |
"To assess the effect of a single oral dose of caffeine (5 mg/kg) on FEV1 and bronchial responsiveness to histamine a double blind, placebo controlled study was performed in eight patients with mild stable asthma." | 9.07 | Decrease of histamine induced bronchoconstriction by caffeine in mild asthma. ( Fuller, RW; Henderson, JC; O'Connell, F, 1993) |
" In a double blind, randomised, crossover study the effect of preservatives in determining the airway responses to 5 mg of terbutaline was studied in a group of 21 atopic asthmatic patients." | 9.07 | Effect of preservative on the efficacy of terbutaline nebuliser solution in atopic asthma. ( Chan, CH; Lai, CK, 1993) |
"A double-blind, randomized, placebo-controlled, parallel-group study was undertaken in 120 clinically stable asthmatic children (aged 6-19 years) to determine the ability of 8 weeks of treatment with nedocromil sodium (4 mg, three times a day) to reduce the level of histamine responsiveness." | 9.07 | The effect of nedocromil sodium on histamine responsiveness in clinically stable asthmatic children. ( Burton, PR; Foo, AL; Lanteri, CJ; Sly, PD, 1993) |
"The effect of indomethacin on the capacity of LTE4 to enhance airway histamine responsiveness was evaluated in eight mild asthmatic subjects." | 9.07 | Effect of indomethacin on leukotriene4-induced histamine hyperresponsiveness in asthmatic subjects. ( Christie, PE; Hawksworth, R; Lee, TH; Spur, BW, 1992) |
"We studied the comparative modification of histamine- and methacholine-induced bronchoconstriction by a calcium antagonist, gallopamil, in 8 subjects with bronchial asthma." | 9.07 | Modification of histamine- and methacholine-induced bronchoconstriction by calcium antagonist gallopamil in asthmatics. ( Ahmed, T; Danta, I, 1992) |
"Sixteen subjects with mild stable asthma participated in a randomized double blind study on the effects of low dose fenoterol against histamine induced bronchoconstriction." | 9.07 | Low dose fenoterol aerosol protects against histamine-induced bronchoconstriction in mild asthmatics: a dose response study. ( Magnussen, H; Rabe, KF, 1992) |
"To examine whether leukotrienes, histamine, and methacholine have different sites of bronchoconstrictor action, we studied 8 stable asthmatic subjects (mean age +/- SD, 26 +/- 5 yr) on 3 different days." | 9.07 | Changes in cross-sectional airway areas induced by methacholine, histamine, and LTC4 in asthmatic subjects. ( Drazen, JM; Hoffstein, V; McClean, PA; Molfino, NA; Rebuck, AS; Slutsky, AS; Zamel, N, 1992) |
"The effect of gallopamil on the late-phase response to inhaled allergen was evaluated in six young adults with allergic asthma in a crossover manner." | 9.07 | The effect of inhaled gallopamil, a potent calcium channel blocker, on the late-phase response in subjects with allergic asthma. ( Harman, E; Hendeles, L; Hoppe, M, 1992) |
"The effect of hyposensitization (HS) upon the allergen evoked immediate asthmatic reaction (IAR), late asthmatic reaction (LAR) and upon bronchial reactivity towards histamine was examined." | 9.07 | Effect of hyposensitization upon the immediate and late asthmatic reaction and upon histamine reactivity in patients allergic to house dust mite (Dermatophagoides pteronyssinus). ( Stevens, WJ; Van Bever, HP, 1992) |
" We investigated the contribution of the mast cell products, histamine and prostaglandins, to the bronchoconstriction induced by isocapnic hyperventilation (ISH) using single doses of terfenadine, a specific histamine H1-receptor antagonist, and flurbiprofen, a potent cyclooxygenase inhibitor." | 9.07 | The relative contributions of histamine and prostanoids to bronchoconstriction provoked by isocapnic hyperventilation in asthma. ( Finnerty, JP; Harvey, A; Holgate, ST, 1992) |
"Astemizole, administered for seven days to asthmatic subjects, had an effect of bronchoconstriction induced by inhaled histamine for a mean period of 42 days." | 9.07 | Single-dose effect of astemizole on bronchoconstriction induced by histamine in asthmatic subjects. ( Benoît, C; Cartier, A; Ghezzo, H; Malo, JL, 1992) |
"Ibudilast, a unique agent with vasodilating and antiallergic actions, was studied in 13 asthmatics for its effect on airway hypersensitivity to histamine inhalation." | 9.07 | Effect of ibudilast: a novel antiasthmatic agent, on airway hypersensitivity in bronchial asthma. ( Hoshino, K; Kawasaki, A; Mizushima, Y; Osaki, R; Yano, S, 1992) |
"The effects of prior inhalation of each of the sulfidopeptide leukotrienes (LT), LTC4, LTD4, and LTE4 on airway responsiveness to histamine have been compared in seven asthmatic and six normal subjects." | 9.07 | Leukotrienes C4, D4, and E4 enhance histamine responsiveness in asthmatic airways. ( Arm, JP; Fong, CY; Hawksworth, RJ; Lee, TH; O'Hickey, SP; Spur, BW, 1991) |
" The effect of both a single dose (15 mg) and 7 days of treatment (15 mg twice daily) with cetirizine, a potent H1 antagonist on bronchoconstriction induced by histamine and leukotriene D4 (LTD4) has been examined in 10 patients with mild atopic asthma in a placebo-controlled, double-blind, crossover study." | 9.07 | Effect of cetirizine on histamine- and leukotriene D4-induced bronchoconstriction in patients with atopic asthma. ( De Vos, C; Ghosh, SK; McIlroy, I; Patel, KR, 1991) |
"The effect of felodipine, a new selective calcium antagonist, was assessed on histamine and adenosine monophosphate (AMP) induced bronchoconstriction in 9 mild atopic asthmatics." | 9.07 | Effect of felodipine on histamine and adenosine induced bronchoconstriction in patients with asthma. ( Ghosh, SK; Rafferty, P, 1991) |
"Recent studies have demonstrated that elevation of plasma atrial natriuretic factor (ANF) levels may produce significant bronchodilation in the constricted asthmatic airway." | 9.07 | Influence of elevated plasma levels of atrial natriuretic factor on bronchial reactivity in asthma. ( Connell, JM; Hulks, G; Jardine, AG; Thomson, NC, 1991) |
"Antiinflammatory therapy with inhaled budesonide is an effective first-line treatment for patients with newly detected, mild asthma, and it is superior to the use of terbutaline in such patients." | 9.07 | Comparison of a beta 2-agonist, terbutaline, with an inhaled corticosteroid, budesonide, in newly detected asthma. ( Haahtela, T; Järvinen, M; Kava, T; Kiviranta, K; Koskinen, S; Lehtonen, K; Nikander, K; Persson, T; Reinikainen, K; Selroos, O, 1991) |
"Bradykinin, a nonapeptide cleavage product of high molecular weight kininogen, is a potent bronchoconstrictor agonist in asthma; however, its mechanism of action is not known." | 9.06 | Contribution of histamine and prostanoids to bronchoconstriction provoked by inhaled bradykinin in atopic asthma. ( Holgate, ST; Lai, CK; Phillips, GD; Polosa, R, 1990) |
"We compared the effects of pretreatment of 800 micrograms of inhaled Smith Kline & French (SK&F) 104353, a leukotriene receptor antagonist, and 120 mg of oral terfenadine on the bronchial responses to inhaled histamine in 12 subjects with asthma." | 9.06 | Effects of SK&F 104353, a leukotriene receptor antagonist, on the bronchial responses to histamine in subjects with asthma: a comparative study with terfenadine. ( Dinh Xuan, AT; Lockhart, A; Marsac, J; Regnard, J; Rey, J; Similowski, T, 1990) |
"In a double blind, randomised, placebo controlled trial in a group of extrinsic asthmatics, we have evaluated the potency and selectivity of ebastine, a new piperidine-type H1-receptor antagonist, against histamine and methacholine-induced bronchoconstriction." | 9.06 | Dose-response relationship of the H1-histamine antagonist, ebastine, against histamine and methacholine-induced bronchoconstriction in patients with asthma. ( Holgate, ST; Wood-Baker, R, 1990) |
"Bronchial histamine provocation tests were performed in nine patients with nonallergic asthma on four consecutive days 45 minutes after inhalation of placebo or ipratropium bromide in a dose-response manner (40 micrograms, 200 micrograms, and 800 micrograms)." | 9.06 | Airways responses to ipratropium bromide do not vary with time in asthmatic subjects. Studies of interindividual and intraindividual variation of bronchodilatation and protection against histamine-induced bronchoconstriction. ( Ihre, E; Larsson, K, 1990) |
" In a randomized, double-blind, crossover study, we evaluated the effects of loratadine, 10 and 20 mg, and placebo administered once daily for 3 days on the skin-wheal responses to histamine, the airway responses to inhaled histamine and methacholine, and the skin-wheal and airway responses to allergen in 12 subjects with asthma." | 9.06 | Comparison of the effect of loratadine on the airway and skin responses to histamine, methacholine, and allergen in subjects with asthma. ( Holgate, ST; Town, GI, 1990) |
"We have investigated the ability of salbutamol to protect against bronchoconstriction induced by methacholine, histamine, and adenosine 5'-monophosphate (AMP) in nine subjects with asthma." | 9.06 | Comparative protective effect of the inhaled beta 2-agonist salbutamol (albuterol) on bronchoconstriction provoked by histamine, methacholine, and adenosine 5'-monophosphate in asthma. ( Finnerty, JP; Holgate, ST; Phillips, GD, 1990) |
"It was recently reported that caffeine may reduce the clinical symptoms of asthma and may prevent the clinical manifestations of this disease." | 9.06 | Effect of caffeine on histamine bronchoprovocation in asthma. ( Bertolo, L; Cohen, C; Colacone, A; Kreisman, H; Wolkove, N, 1990) |
"Inhaled adenosine 5'-monophosphate (AMP) induces bronchoconstriction in subjects with asthma, probably caused by histamine release from airway mast cells, and repeated AMP bronchial challenge leads to attenuation of the bronchoconstrictor response." | 9.06 | Repeated exposure of asthmatic airways to inhaled adenosine 5'-monophosphate attenuates bronchoconstriction provoked by exercise. ( Finnerty, JP; Holgate, ST; Polosa, R, 1990) |
"Nitrendipine was given to eight patients with chronic stable asthma prior to a histamine challenge study and compared in a double-blind cross-over fashion with placebo." | 9.06 | Nitrendipine therapy in asthmatic subjects. ( Cormie, P; Harvey, J; Marley, JE; Mulloy, EM, 1990) |
"Inhalation of an aerosolized solution of lysine-aspirin has previously been described as a safer technique than oral challenge with aspirin for the diagnosis of aspirin-sensitive asthma." | 9.06 | Inhaled lysine-aspirin as a bronchoprovocation procedure in aspirin-sensitive asthma: its repeatability, absence of a late-phase reaction, and the role of histamine. ( Foord, R; Holgate, ST; Phillips, GD, 1989) |
"2 mg three times daily), both administered by powder inhaler, on bronchial hyperresponsiveness (BHR) to histamine in children, aged 7 to 15 years with mild stable asthma and limited bronchoconstriction who had a highly increased BHR." | 9.06 | Long-term effect of ipratropium bromide and fenoterol on the bronchial hyperresponsiveness to histamine in children with asthma. ( Kerrebijn, KF; Mulder, P; Raes, M, 1989) |
"Seventeen patients with perennial asthma, stable on a moderate dose of inhaled steroid, participated in a crossover study comparing the clinical effect of a non-sedative, potent and highly selective H1 antagonist (loratadine 10 mg) with placebo." | 9.06 | Effect of a non-sedative antihistaminic (loratadine) in moderate asthma. A double-blind controlled clinical crossover-trial. ( Dirksen, A; Engel, T; Frølund, L; Heinig, JH; Svendsen, UG; Weeke, B, 1989) |
"Inhaled adenosine and adenosine 5'-monophosphate (AMP) cause bronchoconstriction in atopic and nonatopic asthmatics by a mechanism believed to involve histamine release from airway mast cells and an interaction with neural reflexes." | 9.06 | The effect of oral terfenadine alone and in combination with flurbiprofen on the bronchoconstrictor response to inhaled adenosine 5'-monophosphate in nonatopic asthma. ( Holgate, ST; Phillips, GD, 1989) |
"Percentage reductions in the peak flow rates to a standardized number of histamine inhalations were compared after 7 days of treatment with 10 mg bd tazifylline and after 7 days of placebo in a randomized crossover study in 11 male seasonal atopic asthmatics." | 9.06 | The reducing effects of tazifylline on histamine-induced bronchoconstriction in atopic asthmatics. ( Harlow, B; Kiviranta, K; Reuter, C; Scott, J; Stenius-Aarniala, B, 1989) |
"A double-blind crossover study of the effects of real and placebo acupuncture on bronchial reactivity to histamine was carried out on 16 patients with moderately severe asthma." | 9.06 | Comparison of real and placebo acupuncture in histamine-induced asthma. A double-blind crossover study. ( Soh, PF; Tandon, MK, 1989) |
"Inhaled topical lidocaine, used to produce anesthesia of the respiratory tract prior to bronchoscopy, may cause bronchoconstriction in asthmatic patients." | 9.06 | Lidocaine-induced bronchoconstriction in asthmatic patients. Relation to histamine airway responsiveness and effect of preservative. ( McAlpine, LG; Thomson, NC, 1989) |
"Eight subjects with asthma inhaled on separate occasions leukotriene E4 (LTE4) (6." | 9.06 | The effects of inhaled leukotriene E4 on the airway responsiveness to histamine in subjects with asthma and normal subjects. ( Arm, JP; Lee, TH; Spur, BW, 1988) |
" To evaluate this oral drug's efficacy in treating asthma, we examined the bronchodilator effects of 5-, 10-, and 20-mg doses as well as the protective effects of these doses against histamine-provoked bronchospasm." | 9.06 | Cetirizine inhibition of histamine-induced bronchospasm. ( Brik, A; Gong, H; Tashkin, DP, 1987) |
" The effects of pretreatment with clonidine and rilmenidine, a new alpha 2-adrenoceptor agonist, on the bronchial responses to inhaled histamine were studied on 3 different days in a controlled, double-blind, randomized study in 12 asymptomatic asthmatic subjects." | 9.06 | Comparative effects of rilmenidine and clonidine on bronchial responses to histamine in asthmatic subjects. ( Advenier, C; Dinh Xuan, AT; Lockhart, A; Matran, R; Regnard, J; Vitou, P, 1988) |
"Bronchial mucociliary clearance (CB) and tracheal mucus velocity (TMV) were measured during the course of repeated inhalations of histamine in six subjects with asthma who had no symptoms in a double-blind, crossover study with a radioaerosol technique." | 9.06 | Lung mucociliary transport in asymptomatic asthma: effects of inhaled histamine. ( Garrard, CS; Lourenço, RV; Mussatto, DJ, 1989) |
"The effect of a potent inhibitor of angiotensin-converting enzyme, ramipril, was studied on both inhaled histamine and bradykinin-induced bronchoconstriction in six male, normotensive, mild asthmatic subjects." | 9.06 | The effect of an angiotensin converting enzyme inhibitor, ramipril, on bronchial responses to inhaled histamine and bradykinin in asthmatic subjects. ( Barnes, PJ; Dixon, CM; Fuller, RW, 1987) |
"The effect of pretreatment with nifedipine 20 mg sublingually on the bronchoconstrictor response to inhaled histamine and methacholine in asthmatic and normal subjects has been studied." | 9.06 | The effect of nifedipine on bronchial reactivity to inhaled histamine and methacholine: a comparative study in normal and asthmatic subjects. ( Costello, JF; Henderson, AF, 1988) |
" The protective effects of oral trifluoperazine (TFP) (7 mg) against standardized methacholine and histamine inhalation tests (MIT and HIT) were examined 2 and 22 h post-treatment in eight stable asthmatics using a randomized double-blind protocol." | 9.06 | The effect of trifluoperazine on bronchial responsiveness in asthma. ( Bowden, JJ; Crockett, AJ; Latimer, KM; Ruffin, RE, 1988) |
"The effect of cromolyn sodium (CS) pressurized aerosol on bronchial hyperreactivity was assessed by comparison with placebo in a double-blind crossover study of 14 adult patients with clinically stable asthma." | 9.06 | A controlled study on the effect of treatment with cromolyn sodium pressurized aerosol on bronchial reactivity in patients with asthma. ( Laitinen, LA; Poppius, H; Venho, K, 1986) |
"Single-dose salbutamol (200 micrograms), beclomethasone dipropionate (200 micrograms), and sodium cromoglycate (SCG) (10 mg) administered by inhalation 10 minutes before allergen challenge were examined with regard to inhibition of allergen-induced early (EAR) and late (LAR) asthmatic responses and allergen-induced increase in bronchial responsiveness to inhaled histamine." | 9.06 | Comparative effects of inhaled salbutamol, sodium cromoglycate, and beclomethasone dipropionate on allergen-induced early asthmatic responses, late asthmatic responses, and increased bronchial responsiveness to histamine. ( Cockcroft, DW; Murdock, KY, 1987) |
"Eight nonsmoking subjects with asthma, nonresponsive to the bronchoconstrictive effect of oral propranolol, were studied." | 9.06 | Increased responsiveness to histamine after propranolol in subjects with asthma nonresponsive to the bronchoconstrictive effect of propranolol. ( Carpentiere, G; Castello, F; Marino, S, 1988) |
"Changes in airway responsiveness to histamine after allergen inhalation challenge were studied in 14 nonsmoking atopic adult subjects with asthma." | 9.06 | Increases in airway responsiveness to histamine precede allergen-induced late asthmatic responses. ( Benson, MK; Cookson, WO; Craddock, CF; Durham, SR, 1988) |
"Histamine tachyphylaxis develops with repeated inhalation of histamine in asthmatic subjects, and this appears to be due to the release of inhibitory prostaglandins." | 9.06 | A new role for histamine H2-receptors in asthmatic airways. ( Jackson, PJ; Manning, PJ; O'Byrne, PM, 1988) |
"We evaluated the efficacy of an oral dosage form of the investigational smooth muscle relaxant, zindotrine, a novel pyridazine derivative, in counteracting histamine-induced bronchospasm in a group of 12 non-medicated asymptomatic asthmatics." | 9.06 | The effect of oral zindotrine (MDL-257), a bronchial smooth muscle relaxant, on histamine airways responsiveness in asymptomatic asthmatics. ( Bangs, SE; Barker, KB; Diamond, L; Gordon, EE; Küng, M, 1987) |
"This study was performed in a randomized double-blind manner on 6 separate days in 10 asthmatic patients to investigate the effect of a sustained theophylline on baseline bronchial hyperreactivity to histamine in relation to the theophylline serum levels and the degree of bronchodilatation produced." | 9.06 | Relationship of serum theophylline concentrations to histamine-induced bronchospasm. ( Ciccarello, C; Crimi, N; Distefano, SM; Mistretta, A; Oliveri, R; Palermo, B; Palermo, F; Vancheri, C, 1987) |
"The bronchial responsiveness of a group of asthmatic children was studied using histamine stimulation after a single dose of theophylline and after placebo." | 9.06 | Protective effect of theophylline on histamine-induced bronchoconstriction in asthmatic children. ( Levene, S; McKenzie, SA, 1986) |
"The airway and cardiovascular effects of separate single oral doses of 50, 100 and 200 mg of bucindolol were compared to those of placebo in a double-blind trial in 16 patients with mild to moderately severe asthma." | 9.06 | The effect of bucindolol on the airway function of asthmatics. ( Alpers, JH; Crockett, AJ; Ruffin, RE, 1986) |
"We investigated the possibility that clonidine, an alpha 2-adrenoceptor agonist, can reduce the wheal-and-flare reactions induced by intradermal injections of allergen in patients with extrinsic asthma." | 9.06 | Inhibitory effects of clonidine on the allergen-induced wheal-and-flare reactions in patients with extrinsic asthma. ( Andersson, RG; Brundin, A; Lindgren, BR, 1987) |
"The effects of inhaled MgSO4 on histamine bronchoprovocation test (BPT) were studied in nine asthmatics in clinical remission (FEV1 greater than 80% of predicted)." | 9.06 | Reduction of histamine-induced bronchoconstriction by magnesium in asthmatic subjects. ( Arossa, W; Bucca, C; Bugiani, M; Rolla, G; Spinaci, S, 1987) |
"The influence of circulating noradrenaline on bronchial reactivity to histamine was investigated in eight asthmatic patients." | 9.06 | No influence of circulating noradrenaline on bronchial reactivity to histamine in asthmatic patients. ( Hjemdahl, P; Larsson, K, 1986) |
"The reproducibility of the histamine challenge in seven asymptomatic patients with extrinsic asthma, provoked four times each with 1-2 weeks interval, was investigated." | 9.05 | Histamine-induced bronchospasm. Its reproducibility and usage in clinical evaluation of the sub-threshold bronchodilating dose of a new beta-agonist, KWD 2131. ( Hegardt, B; Löwhagen, O; Svedmyr, N, 1980) |
"The effect of an H1 antihistamine, an H2 antihistamine, and the combination of the two drugs on both histamine-induced bronchoconstriction and dermal whealing was examined in five patients with mild asthma." | 9.05 | A comparison of the actions of H1 and H2 antihistamines on histamine-induced bronchoconstriction and cutaneous wheal response in asthmatic patients. ( Nathan, RA; Schocket, AL; Segall, N, 1981) |
"The effect of prazosin, a potent and specific alpha 1-adrenoceptor antagonist given by inhalation (total nebulized 2 mg) was compared with placebo in a double-blind randomized study of 10 atopic asthmatic children." | 9.05 | Prazosin, an alpha 1-adrenoceptor antagonist, partially inhibits exercise-induced asthma. ( Barnes, PJ; Vickers, H; Wilson, NM, 1981) |
"Vasoactive intestinal peptide (VIP) caused significant bronchodilatation in seven asthmatic volunteers when given intravenously at the rate of 6 pmol/kg/min for 15 min during a double-blind study." | 9.05 | Vasoactive intestinal peptide causes bronchodilatation and protects against histamine-induced bronchoconstriction in asthmatic subjects. ( Morice, A; Sever, PS; Unwin, RJ, 1983) |
"Eight asthmatic patients and two normal subjects performed two identical exercise tests 140 minutes apart (first test preceded by inhalation of saline and the second by terbutaline sulphate)." | 9.05 | Arterial plasma histamine levels at rest, and during and after exercise in patients with asthma: effects of terbutaline aerosol. ( Anderson, SD; Bye, PT; Ferris, L; Schoeffel, RE; Seale, JP; Taylor, KM, 1981) |
"To evaluate the effect of negative ionisation of inspired air on bronchial reactivity, 11 asthmatic children were challenged twice by exercise and 10 were challenged twice by histamine inhalation." | 9.05 | Effect of negative ionisation of inspired air on the response of asthmatic children to exercise and inhaled histamine. ( Amirav, I; Amitai, I; Bar-Yishay, E; Ben-Dov, I; Godfrey, S; Shochina, M, 1983) |
"Eight young men with documented exercise-induced asthma each performed two standard exercise tests and underwent two histamine challenges on separate days after double blind administration of either 20 mg nifedipine or placebo." | 9.05 | Nifedipine in the prevention of asthma induced by exercise and histamine. ( Corris, PA; Gibson, GJ; Nariman, S, 1983) |
"Ten asthmatic children who gave a history of cough or wheeze after orange drinks, were tested for tartrazine sensitivity." | 9.05 | Oral tartrazine challenge in childhood asthma: effect on bronchial reactivity. ( Dixon, C; Hariparsad, D; Silverman, M; Wilson, N, 1984) |
"The effects of a therapeutic serum theophylline concentration on inhaled methacholine and histamine were studied in 8 stable, moderately severe asthmatic children 8 to 15 yr of age." | 9.05 | Effects of theophylline on inhaled methacholine and histamine in asthmatic children. ( Howick, J; Kelly, HW; McWilliams, BC; Menendez, R, 1984) |
"Parenterally administered diphemanil methylsulfate, a quarternary ammonium compound with both parasympatholytic and direct bronchial smooth muscle relaxing properties, has been found effective in the treatment of bronchial asthma." | 9.05 | Effect of inhaled diphemanil methylsulfate, a parasympatholytic agent, on histamine induced bronchoconstriction in asymptomatic asthmatics. ( Diamond, L; Küng, M, 1984) |
"The excretion of histamine (Hi) and it metabolite methyhistamine (MeHi) was determined in separated fractions of urine up to 12h after standardized allergen provocations in 18 adult patients with defined extrinsic bronchial asthma." | 9.05 | Studies on histamine metabolism in allergen-induced asthma. ( Granerus, G; Löwhagen, O; Wetterqvist, H, 1980) |
"Inhalation histamine challenges were performed in groups of normal and asthmatic subjects." | 9.05 | Prostaglandins and the control of airways responses to histamine in normal and asthmatic subjects. ( Walters, EH, 1983) |
"We compared the effects of two histamine receptor blocking agents, chlorpheniramine (H1) and cimetidine (H2) on the airways of healthy and asthmatic subjects." | 9.05 | Histamine blocking agents in healthy and asthmatic subjects. ( Brown, S; Gerstenhaber, B; Lach, E; Schachter, EN, 1982) |
"Plasma histamine and serum neutrophil chemotactic activity (S-NCA) were measured in ten atopic asthmatic patients on four separate occasions after allergen bronchial provocation testing (BPT)." | 9.05 | Circulating histamine and neutrophil chemotactic activity during allergen-induced asthma: the effect of inhaled antihistamines and anti-allergic compounds. ( Cundell, DR; Davies, RJ; Moodley, I; Morgan, DJ; Sheinman, BD; Smart, W, 1985) |
"This study was designed to assess the acute effect of 1 mg of orally administered ketotifen on the dose-response curve to both histamine and methacholine, in 15 patients with bronchial asthma." | 9.05 | Acute effect of ketotifen on the dose-response curve of histamine and methacholine in asthma. ( Barja, S; Cruz, E; Ferretti, R; Lisboa, C; Moran, J; Moreno, R; Sanchez, I, 1985) |
"The airway response to increasing concentrations of inhaled-adenosine and histamine after oral theophylline or matched placebo was studied in nine asthmatic subjects." | 9.05 | Specific antagonism of adenosine-induced bronchoconstriction in asthma by oral theophylline. ( Holgate, ST; Mann, JS, 1985) |
"We performed a double-blind crossover study to compare the effects of long-term treatment of inhaled budesonide and terbutaline on bronchial hyperreactivity in 17 patients with allergic asthma." | 9.05 | Changes in bronchial hyperreactivity induced by 4 weeks of treatment with antiasthmatic drugs in patients with allergic asthma: a comparison between budesonide and terbutaline. ( de Vries, K; Koëter, GH; Kraan, J; Sluiter, HJ; vd Mark, TW, 1985) |
"The protective anti-asthmatic effect of a new anti-allergic drug with histaminolytic and anti-anaphylactic properties was tested in various controlled clinical studies of induced bronchospasm in asthmatic patients (provocation tests using a histamine aerosol, and exercise-induced asthma using a bicycle ergometer)." | 9.04 | [Drug prevention of bronchial asthma: inhibition of histamine and exercise-induced asthma by a new anti-anaphylactic oral preparation (ketotifen) (author's transl)]. ( Radielovic, P; Wüthrich, B, 1978) |
"1 Two studies have been carried out to investigate the effect of H1- and H2-receptor blocking agents on histamine-induced bronchoconstriction in non-asthmatic subjects." | 9.04 | Effects of H1- and H2-receptor blocking agents on histamine-induced bronchoconstriction in non-asthmatic subjects. ( Maconochie, JG; Richards, DA; Woodings, EP, 1979) |
"This study was designed to examine the effect of an H1 antihistamine, chlorpheniramine, an H2 antihistamine, cimetidine, and the combination of chlorpheniramine and cimetidine on histamine-induced bronchoconstriction in a double-blind, randomized protocol on 11 patients with asthma." | 9.04 | The effects of H1 and H2 antihistamines on histamine inhalation challenges in asthmatic patients. ( Glover, GC; Nathan, RA; Schocket, AL; Segall, N, 1979) |
"The effect of inhalation of 2 per cent solution of sodium cromoglycate compared to that of saline on the bronchial response to methacholine and histamine was studied in 30 asthmatic children." | 9.04 | Sodium cromoglycate-induced changes in the dose-response curve of inhaled methacholine and histamine in asthmatic children. ( Kattan, M; Levison, H; Woenne, R, 1979) |
"Out of 19 patients with extrinsic bronchial asthma challenged with 123 mug histamine acid phosphate by intravenous infusion only 13 responded with a fall in FEV1 of over 10% (mean 16%)." | 9.04 | Bronchial reactivity to histamine before and after sodium cromoglycate in bronchial asthma. ( Kang, B; Lee, CK; Miller Kolotkin, B; Townley, RG, 1976) |
"The action mechanism of cromolyn sodium and its effect on bronchial sensitivity to allergen, methacholine chloride, and histamine inhalations were studied in 17 asthmatic subjects." | 9.04 | Cromolyn therapy in patients with bronchial asthma. Effect on inhalation challenge with allergen, histamine, and methacholine. ( Kang, B; Ryo, UY; Townley, RG, 1976) |
"The influence on airway conductance of inhaled aerosols of prostaglandin F(2)alpha (PGF(2)alpha), histamine, and prostaglandin E(2) (PGE(2)) was studied in 10 patients with spirometrically reversible bronchial asthma and in 10 healthy subjects with no history of lung disorder." | 9.04 | Bronchial hyperreactivity to prostaglandin F 2 and histamine in patients with asthma. ( Hedqvist, P; Holmgren, A; Mathé, AA; Svanborg, N, 1973) |
" Histamine is a central mediator released from mast cells through allergic reactions." | 9.01 | The Role of Histamine in the Pathophysiology of Asthma and the Clinical Efficacy of Antihistamines in Asthma Therapy. ( Ogasawara, M; Yamauchi, K, 2019) |
"Histamine has been reported to play an important role in pathogenesis of bronchial asthma." | 8.87 | [Roles of histamine in the pathogenesis of bronchial asthma and reevaluation of the clinical usefulness of antihistamines]. ( Kobayashi, H; Maeyama, K; Nakamura, Y; Ogasawara, M; Shikanai, T; Yamauchi, K, 2011) |
"The histamine H4 receptor is expressed preferentially on immune cells, indicating a possible role of the H4 receptor in inflammation." | 8.86 | Does the histamine H4 receptor have a pro- or anti-inflammatory role in murine bronchial asthma? ( Beermann, S; Neumann, D; Seifert, R, 2010) |
"Cumulative clinical and laboratory evidence on histamine and its actions suggests that it has a pathophysiologic role in asthma." | 8.81 | Role of histamine in the pathophysiology of asthma: immunomodulatory and anti-inflammatory activities of H1-receptor antagonists. ( Gelfand, EW, 2002) |
"Airway hyperresponsiveness to histamine is a hallmark of asthma, and histamine inhalation reproduces asthma symptoms." | 8.80 | Is antihistamine (H1-receptor antagonist) therapy useful in clinical asthma? ( Simons, FE, 1999) |
"Histamine plays a critical role in the pathogenesis of bronchial asthma." | 8.79 | [Regulation of gene expression of L-histidine decarboxylase and histamine N-methyl-transferase, and its relevance to the pathogenesis of bronchial asthma]. ( Yamauchi, K, 1996) |
"Antihistamines were investigated for use in asthma shortly after discovery over fifty years ago." | 8.79 | Antihistamines in the treatment of asthma. ( Grant, JA; Malick, A, 1997) |
"Histamine is an important mediator of asthma." | 8.78 | Antihistamines in the treatment of asthma. ( Bousquet, J; Godard, P; Michel, FB, 1992) |
"Because the older antihistamines possessed relatively weak antihistaminic action, as well as sedative and anticholinergic effects, they could not be administered in doses high enough to confer relief to atopic patients with asthma." | 8.78 | Antihistamines in the treatment of clinical asthma. ( Rafferty, P, 1990) |
"In addition to bronchial smooth muscle, histamine and other mediators act in bronchial asthma on the microcirculation of pulmonary connective tissue." | 8.77 | The role of histamine and other mediators in microvascular changes in acute inflammation. ( Movat, HZ, 1987) |
"Endogenous adenosine 5'-monophosphate (AMP), acetylcholine (ACh), and histamine (HA) are known to be important in bronchial contraction, but their clinical relevance to asthma is poorly understood." | 8.12 | Endogenous Adenosine 5'-Monophosphate, But Not Acetylcholine or Histamine, is Associated with Asthma Control, Quality of Life, and Exacerbations. ( Deng, K; Fang, XM; Huang, D; Li, WM; Liu, D; Liu, L; Liu, Y; Luo, FM; Oliver, BG; Wan, HJ; Wang, G; Wang, J; Wang, L; Zhang, HP; Zhang, L; Zhang, X, 2022) |
"To observe the effect of moxibustion on respiratory function and contents of histamine and neuropeptides in skin tissue of "Feishu" (BL13) in asthmatic rats, so as to explore its mechanisms underlying improvement of asthma." | 7.96 | [Effect of moxibustion on respiratory function and cutaneous histamine and neuropeptide contents of "Feishu" (BL13) in asthmatic rats]. ( Pan, J; Qiu, RR; Wang, CX; Yang, RD; Zhang, C; Zhang, GS; Zhang, J, 2020) |
"The rationale of this study is that, treatment of asthmatic Guinea pig with combined administration of Montelukast sodium and Green Tea Extract (GTE) as a single capsule will mitigate the inflammatory injury in the airways and weaken the asthmatic response." | 7.88 | Montelukast Sodium Formulation Containing Green Tea Extract to Reduce the Oxidative Stress in Guinea Pig Model of Chronic Allergic Asthma. ( Kulkarni, GT; Kumar, Y; Singh, N, 2018) |
"Adenosine monophosphate (AMP) may reflect airway inflammation and hyperresponsiveness, but relationship between AMP and histamine (His, a conventional stimulus) bronchial provocation test (BPT) in asthma is not fully elucidated." | 7.85 | Adenosine monophosphate is not superior to histamine for bronchial provocation test for assessment of asthma control and symptoms. ( An, JY; Gao, Y; Guan, WJ; Liu, WT; Wu, F; Xie, YQ; Yu, XX; Zheng, JP, 2017) |
"The following methods were used in experiments: the in-vitro tracheal smooth muscle contraction induced by histamine; the changes in specific airway resistance (sRaw) to histamine and the sensitivity of a chemically induced cough reflex both via an in-vivo method; the serum and BALF concentrations' analysis of the inflammatory cytokines interleukin IL-4, IL-5, IL-13; and lung tissue infiltration by eosinophils and mastocytes." | 7.83 | Bronchodilatory, antitussive and anti-inflammatory effect of morin in the setting of experimentally induced allergic asthma. ( Franova, S; Joskova, M; Kazimierova, I; Pappova, L; Plank, L; Sutovska, M, 2016) |
" To confirm the histamine-binding capacity of rHa24, a histamine-binding assay was completed in vitro (ELISA) and in vivo by inhibition of allergic asthma in mice." | 7.83 | Specific histamine binding activity of a new lipocalin from Hyalomma asiaticum (Ixodidae) and therapeutic effects on allergic asthma in mice. ( Cao, J; Gong, H; Li, Z; Wang, Y; Zhang, H; Zhou, J; Zhou, Y, 2016) |
"The commercially available alpha-asarone injections (CA-ARE) were frequently found to cause severe anaphylactic reactions by the solubilizer contained in the formulation such as polysorbate 80 and propylene glycol." | 7.81 | Systemic delivery of alpha-asarone with Kolliphor HS 15 improves its safety and therapeutic effect on asthma. ( Gong, T; Li, J; Li, M; Lu, H; Zhang, Z, 2015) |
"Histamine is an important mediator in the pathophysiology of asthma." | 7.81 | Genetic variation within the histamine pathway among patients with asthma--a pilot study. ( Dai, H; Jones, BL; Raje, N; Vyhlidal, CA, 2015) |
"Via the histamine H4 -receptor (H4 R), histamine promotes the pathogenesis of experimental allergic asthma in mice." | 7.81 | The histamine H4 -receptor (H4 R) regulates eosinophilic inflammation in ovalbumin-induced experimental allergic asthma in mice. ( Glage, S; Hartwig, C; Munder, A; Neumann, D; Schenk, H; Seifert, R; Wedekind, D, 2015) |
"Ovalbumin inhalation caused early (EAR) and late asthmatic response (LAR), airway hyper-reactivity to histamine and influx of inflammatory cells into the lungs." | 7.81 | LPS exacerbates functional and inflammatory responses to ovalbumin and decreases sensitivity to inhaled fluticasone propionate in a guinea pig model of asthma. ( Broadley, KJ; Ford, WR; Kidd, EJ; Lowe, AP; Nials, AT; Thomas, RS, 2015) |
"Histamine is an important mediator in the pathogenesis of asthma." | 7.81 | Genetic Variation along the Histamine Pathway in Children with Allergic versus Nonallergic Asthma. ( Anvari, S; Dai, H; Jones, BL; Vyhlidal, CA, 2015) |
" Further, anti-asthmatic potential of curcumin, through intranasal route has been evaluated for the first time in LPS induced airway inflammation in an ovalbumin (OVA)-challenged mouse asthma model." | 7.81 | Lipopolysaccharide (LPS) exposure differently affects allergic asthma exacerbations and its amelioration by intranasal curcumin in mice. ( Dash, D; Kumari, A; Singh, R, 2015) |
"We evaluated the inhibitory effects of flavone derivatives having the chromone moiety on the immediate-phase asthmatic response (IAR) and the late-phase asthmatic response (LAR) to aerosolized-ovalbumin (OA) exposure in conscious OA-sensitized guinea pigs." | 7.80 | Flavones derived from nature attenuate the immediate and late-phase asthmatic responses to aerosolized-ovalbumin exposure in conscious guinea pigs. ( Kim, CJ; Kim, JM; Lee, JY, 2014) |
"Curcumin, a phytochemical present in turmeric, rhizome of Curcuma longa, has been shown to have a wide variety of pharmacological activities including anti-inflammatory, anti-allergic and anti-asthmatic properties." | 7.79 | Intranasal curcumin and its evaluation in murine model of asthma. ( Chauhan, PS; Chawla, R; Dash, D; Kumar, JP; Kumari, S; Singh, M; Singh, R, 2013) |
"1 years) with established asthma (PC(20)FEV(1) histamine below 4 mg/ml) were included in this study." | 7.78 | Mannitol challenge does not confirm bronchial hyperreactivity in some histamine-responsive asthmatic children. ( Siergiejko, G; Siergiejko, Z; Swiebocka, EM, 2012) |
" We isolated caffeic acid and phenylpropanoid glycosides, 1-O-caffeoyl glycoside and acteoside [β-(3',4'-dihydroxyphenyl) ethyl-O-α-l-rhamnopyranosyl(1→3)-β-d-(4-O-caffeoyl)-glucopyranoside] from their ethylacetate fractions, respectively, and evaluated their anti-asthmatic effects on the aerosolized ovalbumin (OA) challenge in the OA-sensitized guinea-pigs measuring the specific airway resistance (sRaw) during the immediate-phase response (IAR) and late-phase response (LAR), and also measured recruitment of leukocytes and chemical mediators on the bronchoalveolar lavage fluids (BALF) in LAR, as well as histopathological survey." | 7.77 | Anti-asthmatic effects of phenylpropanoid glycosides from Clerodendron trichotomum leaves and Rumex gmelini herbes in conscious guinea-pigs challenged with aerosolized ovalbumin. ( Kim, CJ; Lee, JG; Lee, JY; Sim, SS; Whang, WK, 2011) |
"In the present study, the efficacy of β-sitosterol isolated from an n-butanol extract of the seeds of the plant Moringa oleifera (Moringaceae) was examined against ovalbumin-induced airway inflammation in guinea pigs." | 7.77 | Suppression of ovalbumin-induced Th2-driven airway inflammation by β-sitosterol in a guinea pig model of asthma. ( Mahajan, SG; Mehta, AA, 2011) |
"Peripheral blood mononuclear cell from 15 rhinitic and 14 asthmatic HDM-allergic subjects and 16 controls were cultured with Der p 1 or histamine." | 7.76 | Histamine induces Th2 activation through the histamine receptor 1 in house dust mite rhinitic but not asthmatic patients. ( Botturi, K; Lacoeuille, Y; Magnan, A; Vervloet, D, 2010) |
"No subjects with EB responded to either AMP (n = 5) or mannitol (n = 7) while 4/8 and 7/10 subjects with asthma responded to the respective challenges (P = 0." | 7.76 | Mannitol and AMP do not induce bronchoconstriction in eosinophilic bronchitis: further evidence for dissociation between airway inflammation and bronchial hyperresponsiveness. ( Bradding, P; Brightling, CE; McKenna, S; Singapuri, A, 2010) |
"Hypertonic histamine challenge-induced cough and PC(20) are sensitive measures in assessing the treatment effect in asthma." | 7.76 | Assessment of inhaled corticosteroid treatment response in asthma using hypertonic histamine challenge-induced cough. ( Koistinen, T; Kontra, KM; Koskela, H; Peuhkurinen, K; Purokivi, M, 2010) |
" The authors examined the correlation between airway remodeling and bronchial reactivity to histamine (Hist) and acetylcholine (ACh) in patients with moderate to severe asthma." | 7.76 | Bronchial reactivity to histamine is correlated with airway remodeling in adults with moderate to severe asthma. ( Akiyama, K; Mitomi, H; Oshikata, C; Saito, H; Sekiya, K; Takeichi, S; Tanimoto, H; Tsuburai, T; Tsurikisawa, N, 2010) |
"This study aimed to investigate the effect of piperine on airway hyperresponsiveness, pulmonary eosinophilic infiltration, various immune cell phenotypes, Th2 cytokine production, immunoglobulin E and histamine production in a murine model of asthma." | 7.75 | Piperine inhibits eosinophil infiltration and airway hyperresponsiveness by suppressing T cell activity and Th2 cytokine production in the ovalbumin-induced asthma model. ( Kim, SH; Lee, YC, 2009) |
"Effects of quercetin inhalation on immediate (IAR), late-phase (LAR) and late late-phase (LLAR) asthmatic responses by exposure to aerosolized-ovalbumin (AOA) (2w/v% in saline, inhalation for 3 min) were studied in conscious guinea-pigs sensitized with AOA." | 7.74 | Quercetin inhalation inhibits the asthmatic responses by exposure to aerosolized-ovalbumin in conscious guinea-pigs. ( Choi, HH; Kim, CJ; Lee, JY; Moon, H; Moon, HJ; Sim, SS, 2008) |
" The aim of the present study was to evaluate the utility of coughing induced by the hypertonic histamine challenge in the differential diagnosis of asthma in a clinically relevant patient population." | 7.74 | Utility of cough response during hypertonic histamine challenge in diagnosing asthma. ( Kiviniemi, V; Koistinen, T; Kontra, KM; Koskela, HO; Magga, J; Peuhkurinen, K; Purokivi, M, 2008) |
"To assess the prevalence of bronchial hyperresponsiveness (BHR) in a population of north Finland among subjects with no previous diagnosis of asthma or chronic bronchitis by using histamine and methacholine challenges." | 7.74 | Bronchial hyperresponsiveness in a population of north Finland with no previous diagnosis of asthma or chronic bronchitis assessed with histamine and methacholine tests. ( Juusela, M; Kotaniemi, J; Lundbäck, B; Poussa, T; Sovijärvi, A, 2008) |
" Patients with asthma (N=25) underwent a histamine provocation until a 20% fall in forced expiratory volume in 1s (FEV(1))." | 7.74 | Differentiation between the sensory and affective aspects of histamine-induced bronchoconstriction in asthma. ( De Peuter, S; Demedts, M; Lemaigre, V; Van den Bergh, O; Van Diest, I; Verleden, G, 2007) |
"To explore the use of oscillometry as a measure of airway responsiveness, 69 asthmatic children underwent histamine and methacholine bronchoprovocation using dosimeter-MedicAid (Jaeger Co." | 7.74 | The use of oscillometry as a measure of airway responsiveness in asthmatic children after histamine and methacholine bronchoprovocation with dosimeter-MedicAid and DeVilbiss nebulizers. ( Kopriva, F; Látalová, M; Plocová, A; Radová, L; Slezáková, L; Smatanová, D; Szotkowská, J; Zápalka, M; Závodská, J, 2007) |
"The purpose of the present study was to determine the effects of acetaldehyde on airway smooth muscle constriction and inflammation." | 7.74 | Effects of acetaldehyde on human airway constriction and inflammation. ( Fukushima, C; Kohno, S; Matsuse, H; Sadahiro, A; Shimoda, T, 2007) |
"To determine whether oral administration of cyproheptadine or cetirizine blocks the action of serotonin and histamine, respectively, and results in diminished eosinophilic airway inflammation in cats with experimentally induced asthma." | 7.74 | Effects of cyproheptadine and cetirizine on eosinophilic airway inflammation in cats with experimentally induced asthma. ( Jiji, RD; McGee Turner, JB; Reinero, CR; Schooley, EK; Spinka, CM, 2007) |
"Although histamine is a central mediator in the immediate allergic reaction, its role in goblet cell hyperplasia in the airway of asthma is not completely understood." | 7.74 | Progress in allergy signal research on mast cells: the role of histamine in goblet cell hyperplasia in allergic airway inflammation - a study using the Hdc knockout mouse. ( Inoue, H; Ito, H; Kobayashi, H; Maesawa, C; Mouri, T; Nakadate, T; Nakamura, Y; Niisato, M; Ohtsu, H; Piao, HM; Sawai, T; Shikanai, T; Yamauchi, K, 2008) |
"Adenosine, an important signaling molecule in asthma, produces bronchoconstriction in asthmatics." | 7.73 | A novel A1 adenosine receptor antagonist, L-97-1 [3-[2-(4-aminophenyl)-ethyl]-8-benzyl-7-{2-ethyl-(2-hydroxy-ethyl)-amino]-ethyl}-1-propyl-3,7-dihydro-purine-2,6-dione], reduces allergic responses to house dust mite in an allergic rabbit model of asthma. ( Batra, VK; Borron, P; Mustafa, SJ; Nadeem, A; Obiefuna, PC; Wilson, CN, 2005) |
"To investigate the role of histamine in airway remodeling, 50 healthy guinea pigs were divided into 5 groups: control group: nebulized inhalation of distilled water for 8 weeks; asthma model group: nebulized inhalation of ovalbumin (OVA) for 8 weeks after sensitization; continued asthma model group: nebulized inhalation of OVA for 14 weeks after sensitization; histamine group: nebulized inhalation of OVA for 14 weeks after sensitization and histamine was added in the last 6 weeks; antagonist group: nebulized inhalation of OVA for 14 weeks after sensitization and histamine receptor antagonists were added in the last 6 weeks." | 7.73 | Role of histamine in airway remodeling of asthmatic guinea pig. ( Chen, BS; Chen, QL; Liu, SY; Wang, XH; Ye, SQ; Yu, SB, 2005) |
"To investigate whether the perception of dyspnea during histamine-induced bronchoconstriction might be used to identify patients with asthma who sense dyspnea poorly during exacerbation." | 7.73 | Perception of dyspnea during exacerbation and histamine-related bronchoconstriction in patients with asthma. ( Altunkaya, V; Bulcun, E; Ekici, A; Ekici, M; Kara, T; Karlidag, A; Keles, H, 2006) |
" Previously, it is reported that a high dose of L-97-1, a water-soluble, small molecule adenosine A(1) receptor antagonist, blocks early and late allergic responses, and bronchial hyper-responsiveness to histamine in a hyper-responsive rabbit model of allergic asthma." | 7.73 | Adenosine A1 receptor antagonist versus montelukast on airway reactivity and inflammation. ( Mustafa, SJ; Nadeem, A; Obiefuna, PC; Wilson, CN, 2006) |
"The aim of this study was to evaluate the influence of pretreatment with the phosphodiesterase-4 inhibitor rolipram on pulmonary resistance, influx of inflammatory cells, and histamine concentration in bronchoalveolar lavage fluid (BALF) during an experimental asthmatic reaction induced in ovalbumin (OA)-sensitized guinea pigs, challenged with OA inhalation." | 7.73 | Effects of the phosphodiestrase-4 inhibitor rolipram on lung resistance and inflammatory reaction in experimental asthma. ( Chazan, R; Glapiński, J; Grubek-Jaworska, H; Hoser, G; Nejman-Gryz, P, 2006) |
"In our model of asthma, guinea pigs were made sensitive with ovalbumine (OVA), a protein extracted from the white of egg, and provoked in a way repeated with aerosol challenge of OVA for the group OVA (1 challenge a day during six days)." | 7.73 | [Study of cellularity in bronchoalveolar fluid and bronchial reactivity to histamine in a model of asthma in guinea pig]. ( Aubier, M; Boczkowski, J; Lanone, S; Ouksel, H; Pretrolani, M; Samb, A, 2006) |
"To investigate the pathogenic mechanism of late asthmatic response in comparison to early asthmatic response, changes of serum neutrophil chemotactic activity (NCA) using the Boyden chamber method and histamine level using the automated fluorometric analyzer were observed in 13 aspirin (ASA)-sensitive asthma subjects (group I: 7 early responders and group II: 6 dual responders) during lysine aspirin bronchoprovocation test (L-ASA BPT)." | 7.72 | Enhanced serum neutrophil chemotactic activity was noted in both early and late asthmatic responses during lysine-aspirin bronchoprovocation test in ASA-sensitive asthmatic patients. ( Kim, SS; Lee, SK; Lee, YM; Nahm, DH; Park, HS; Yoon, HJ, 2003) |
"Histamine is an important mediator released from activated mast cells provoked by allergen and has a substantial role in the pathophysiology of asthma." | 7.72 | Histamine deficiency in gene-targeted mice strongly reduces antigen-induced airway hyper-responsiveness, eosinophilia and allergen-specific IgE. ( Appel, J; Buzás, E; Falus, A; Keszei, M; Komlósi, Z; Kozma, GT; Losonczy, G; Magyar, P; Pállinger, E; Szabó, T; Szalai, C, 2003) |
"The study objectives were to analyze the changes in exhaled carbon monoxide (COex) induced by histamine provocation challenge in asthmatic patients and to evaluate the relationship between COex and airway sensitivity and reactivity." | 7.72 | Relationship between exhaled carbon monoxide and airway hyperresponsiveness in asthmatic patients. ( García-Río, F; Pino, JM; Prados, C; Ramirez, M; Villamor, J; Viñas, A, 2004) |
"Because histamine receptor type I blockade attenuates allergic asthma, we asked whether complete neutralization of histamine by an arthropod-derived, high affinity histamine-binding protein (EV131) would prevent allergic asthma." | 7.72 | Arthropod-derived histamine-binding protein prevents murine allergic asthma. ( Couillin, I; Jacobs, M; Lefort, J; Maillet, I; Moser, R; Nuttall, PA; Paesen, GC; Ryffel, B; Vargaftig, BB; Weston-Davies, W, 2004) |
"Coupling seratrodast (SD), an antiasthmatic drug, with several different types of NO donors including oxatriazoles, N-hydroxyguanidines and furoxans; evaluating the antiasthmatic effects of coupled compounds by determining their inhibitory activity of guinea pig asthma induced by acetylcholine and histamine; and assessing NO releasing ability." | 7.72 | [Design, synthesis and antiasthmatic activities of NO-donating seratrodast derivatives]. ( Feng, XC; Ji, H; Qiu, SG; Zhang, YH; Zhang, ZG, 2004) |
"Bronchial responsiveness (BR) to histamine or methacholin is a common finding in adult non-asthmatic patients with allergic rhinitis." | 7.71 | Comparison of bronchial responsiveness to histamine in asthma, allergic rhinitis and allergic sensitization at the age of 7 years. ( Lau, S; Nickel, R; Niggemann, B; Sommerfeld, C; Wahn, U, 2002) |
"The aim of the study was to characterize the mechanism of formaldehyde (FM)-induced nasal and bronchial response in asthmatic subjects with suspected FM allergy." | 7.70 | Airway response to formaldehyde inhalation in asthmatic subjects with suspected respiratory formaldehyde sensitization. ( Górski, P; Krakowiak, A; Pazdrak, K; Ruta, U, 1998) |
"Occupational asthma due to western red cedar is associated with histamine release from basophils and mast cells on exposure to plicatic acid (PA), but the mechanisms underlying this response remain unclear." | 7.70 | Is tyrosine kinase activation involved in basophil histamine release in asthma due to western red cedar? ( Chan, H; Chan-Yeung, M; Frew, A; Salari, H, 1998) |
"Alcohol-induced asthma, a phenomenon characteristic of Asians, is due to differences in alcohol metabolism, particularly acetaldehyde metabolism." | 7.70 | Correlation between alcohol-induced asthma and acetaldehyde dehydrogenase-2 genotype. ( Asai, S; Harda, S; Kohno, S; Shimoda, T; Takao, A, 1998) |
"Eight allergic asthmatic subjects, six normal subjects, and six atopic nonasthmatic subjects were challenged with saline in the lingula and with serial concentrations of histamine (1 x 10(-7) to 5 x 10(-5) mol/L) in the right middle lobe followed by bronchoalveolar lavage (BAL) 15 minutes and 6 hours later." | 7.70 | Identification of IL-16 as the lymphocyte chemotactic activity in the bronchoalveolar lavage fluid of histamine-challenged asthmatic patients. ( Center, DM; Cruikshank, WW; Fine, GD; Lim, KG; Mashikian, MV; Saukkonen, JJ; Tarpy, RE, 1998) |
"The release of histamine and leukotriene C4 (LTC4) from bronchoalveolar lavage (BAL) cells and peripheral blood stimulated with Ca ionophore A23187 was compared between atopic and nonatopic asthma." | 7.70 | Different roles of histamine and leukotriene C4 in the airways between patients with atopic and nonatopic asthma. ( Ashida, K; Hosaki, Y; Mifune, T; Mitsunobu, F; Tanizaki, Y; Tsugeno, H; Yokota, S, 1998) |
"We examined the inhibitory effects of azelastine hydrochloride, which inhibits histamine release and blocks H1 receptors, in alcohol-induced asthma." | 7.70 | Inhibitory effects of azelastine hydrochloride in alcohol-induced asthma. ( Asai, S; Kohno, S; Matsuse, H; Mitsuta, K; Obase, Y; Shimoda, T; Takao, A, 1999) |
"To characterize membrane-receptor peculiarities in adrenergic and histaminergic systems under model peroxide effect in bronchial asthma (BA)." | 7.70 | [Membrane-receptor disorders in adrenergic and histaminergic systems under peroxide exposure in bronchial asthma patients]. ( Ivanova, VV; Mineev, VN; Nesterovich, II, 2000) |
"Histamine is involved in the pathophysiology of asthma, and histamine N-methyltransferase (HNMT) plays the dominant role in histamine metabolism in human bronchial epithelium." | 7.70 | Histamine N-methyltransferase pharmacogenetics: association of a common functional polymorphism with asthma. ( Bernstein, JA; Galinsky, RE; Liggett, SB; Weinshilboum, RM; Yan, L, 2000) |
" Bronchial hyperreactivity (BHR) was evaluated with histamine challenge test and the results were compared with those of 20 normal subjects and 20 current asthmatic patients." | 7.70 | Bronchial sensitivity to histamine in former asthmatics: redevelopment of symptoms during a year of followup. ( López, JM; Tálamo, C; Velázquez, J, 2000) |
" The present study was carried out to determine how prednisolone modulates airway response to histamine, including recovery from induced bronchospasm in asthmatics." | 7.70 | Prednisolone hastens recovery from histamine-induced bronchospasm in asthmatics. ( Chhabra, SK; Gupta, M, 2000) |
" Incubation of bronchial epithelial cells from patients with asymptomatic asthma with interleukin-1 or histamine, for 8 to 24 hours, resulted in increased expression of endothelin-1 messenger RNA and release of appreciable amounts of the peptide to the culture medium." | 7.69 | Constitutive expression of endothelin in bronchial epithelial cells of patients with symptomatic and asymptomatic asthma and modulation by histamine and interleukin-1. ( Ackerman, V; Bellini, A; Carpi, S; Marini, M; Mattoli, S; Vassalli, G, 1995) |
"To determine whether a mu opiate agonist can constrict the human airways, the dose of codeine (C) or histamine (H) producing a 40% decrease (PD40) in specific airway conductance (SGAW) was measured in 17 asthmatic and 14 normal subjects." | 7.69 | Codeine-induced bronchoconstriction and putative bronchial opiate receptors in asthmatic subjects. ( Popa, V, 1994) |
"The tracheal sounds of 29 children aged 8-19 years with asthma were recorded during airways obstruction caused by histamine inhalation using a system for continuous respiratory telemetry and computer analysis." | 7.69 | Characteristics of wheeze during histamine-induced airways obstruction in children with asthma. ( Dooijes, EH; Everaerd, WA; Kolk, AM; Prins, PJ; Rietveld, S; Rijssenbeek-Nouwens, LH; Smit, F, 1995) |
"The aim of the study was to investigate the possibility that the scoring of breathlessness during histamine bronchial provocation testing might be used to identify asthmatic subjects who sense dyspnea poorly during spontaneous bronchoconstriction." | 7.69 | A comparison of breathlessness during spontaneous asthma and histamine-induced bronchoconstriction. ( Boudreau, D; Gray-Donald, K; Martin, JG; Styhler, A, 1995) |
"In order to study changes in respiratory sounds associated with acute bronchoconstriction and -dilatation, breath sounds of 11 children with asthma (age range, 10-14 years) were recorded at the chest and at the trachea during histamine challenge test and after subsequent bronchodilatation." | 7.69 | Frequency distribution of breath sounds as an indicator of bronchoconstriction during histamine challenge test in asthmatic children. ( Malmberg, LP; Sorva, R; Sovijärvi, AR, 1994) |
"Our objective was to examine the changes in regional ventilation during histamine-induced bronchoconstriction in stable asthma." | 7.69 | Changes in regional ventilation during histamine bronchial challenge in stable asthma. ( Flenley, DC; Ip, M; Kirby, T; Wathen, CG; Whyte, KF, 1994) |
"In asthmatic patients methacholine or histamine challenge may result in more rapid and shallow breathing." | 7.69 | Histamine induced changes in breathing pattern may precede bronchoconstriction in selected patients with bronchial asthma. ( Duranti, R; Fanelli, A; Gigliotti, F; Gorini, M; Scano, G; Spinelli, A, 1994) |
"We investigated whether an exercise challenge protocol is suitable for measuring bronchial responsiveness in epidemiological studies of asthma in children, and determined its comparability with histamine challenge." | 7.69 | An exercise challenge protocol for epidemiological studies of asthma in children: comparison with histamine challenge. ( Anderson, SD; Haby, MM; Mellis, CM; Peat, JK; Toelle, BG; Woolcock, AJ, 1994) |
"The objective of this study was to determine whether exposure to ozone causes inflammatory or functional changes in the upper or lower airways of asthmatic and nonasthmatic individuals." | 7.69 | Inflammatory effects of ozone in the upper airways of subjects with asthma. ( Henderson, WR; Koenig, JQ; Luchtel, DL; McBride, DE; Williams, PV, 1994) |
"Histamine challenge testing is used to measure airway responsiveness in asthma." | 7.69 | Effect of magnitude of airway responsiveness and therapy with inhaled corticosteroid on histamine tachyphylaxis in asthma. ( Manning, PJ; O'Byrne, PM; Strban, M; Watson, RM, 1994) |
"In a new model using conscious, unrestrained and ovalbumin-sensitized guinea pigs, we investigated the effects of the selective histamine H1 receptor antagonist, mepyramine, on the development of allergen-induced early and late asthmatic reactions, bronchial hyperreactivity and airway inflammation, having each animal as its own control." | 7.69 | Role of histamine in allergen-induced asthmatic reactions, bronchial hyperreactivity and inflammation in unrestrained guinea pigs. ( Meurs, H; Olymulder, CG; Santing, RE; Schraa, EO; Wachters, A; Zaagsma, J, 1994) |
"Air-flow standardized breath sounds were recorded at the chest and at the trachea during histamine challenge test and after subsequent bronchodilation in 12 asthmatics and 6 healthy controls for spectral analysis, to be compared with simultaneous changes in spirometric variables." | 7.69 | Changes in frequency spectra of breath sounds during histamine challenge test in adult asthmatics and healthy control subjects. ( Haahtela, T; Katila, T; Malmberg, LP; Paajanen, E; Piirilä, P; Sovijärvi, AR, 1994) |
"The influence of the breathing pattern on transcutaneous blood gases was evaluated in 18 boys and 8 girls 7-18 years of age, with bronchial asthma, during bronchial provocation with histamine-HCl." | 7.69 | Influence of breathing pattern on transcutaneous oxygen and carbon dioxide tension during histamine provocation in children with bronchial asthma. ( Bjure, J; Engström, I; Holmgren, D; Sixt, R; Sten, G, 1996) |
"We investigated the relation between IgE reactive with histamine-releasing factor (HRF) and clinical status in patients with asthma or rhinitis." | 7.69 | Reactivity to IgE-dependent histamine-releasing activity in asthma or rhinitis. ( Aalbers, M; Aalberse, RC; Jansen, HM; Knol, EF; Pasmans, SG; van der Veen, MJ; van der Zee, JS, 1996) |
"The mean venous plasma histamine of 14 patients with eosinophilia was 18." | 7.69 | Plasma histamine in patients with tropical disorders and acute asthma who exhibit eosinophilia. ( Bruce, C; Taylor, WH, 1996) |
"We have shown that inhalation of lysine aspirin enhances leukotriene production in the lungs of patients with aspirin-induced asthma (AIA)." | 7.69 | Bronchial aspirin challenge causes specific eicosanoid response in aspirin-sensitive asthmatics. ( Dworski, R; Nizankowska, E; Oates, J; Sheller, J; Sladek, K; Soja, J; Szczeklik, A, 1996) |
"Susceptibility to voice reactions during a histamine provocation test was studied in 21 asthmatics and 21 healthy subjects." | 7.69 | Voice reactions to histamine inhalation in asthma. ( Leinonen, L; Poppius, H, 1997) |
"We have compared the bronchoalveolar lavage fluid (BAL) cellular composition and the BAL cell lysate histamine content (fluorometric assay) in 28 stable mild to moderate asthmatics (atopic n = 18 and intrinsic n = 10) and 11 control subjects." | 7.69 | Correlation between bronchoalveolar lavage (BAL) fluid cell lysate histamine content and BAL fluid eosinophil count in atopic and nonatopic asthmatics. ( Corhay, JL; Louis, R; Mendez, P; Poncelet, M; Radermecker, M; Van Tulder, L, 1997) |
"Bronchial responsiveness to inhaled histamine was measured in 100 patients (age range, 28 to 79 years), of whom 62 had intrinsic and 38 had extrinsic asthma." | 7.68 | Bronchial responsiveness to inhaled histamine in both adults with intrinsic and extrinsic asthma: the importance of prechallenge forced expiratory volume in 1 second. ( Ulrik, CS, 1993) |
"The local release of histamine is considered to be largely responsible for the early asthmatic response to inhaled allergen, although its contribution to the late response is less well-established." | 7.68 | Plasma and urinary histamine in allergen-induced early and late phase asthmatic responses. ( Finnerty, JP; Holgate, ST; Wood-Baker, R, 1993) |
"Histamine is a major mediator of the mast cells that are present between epithelial cells in asthma." | 7.68 | Activation by histamine of bronchial epithelial cells from nonasthmatic subjects. ( Bousquet, J; Campbell, AM; Chanez, P; Godard, P; Lacoste, P; Michel, FB; Vignola, AM, 1993) |
"We wanted to determine whether the airway response to inhaled leukotriene C4 (LTC4) is similar to inhaled leukotriene E4 (LTE4) in aspirin-sensitive asthma and, therefore, determined airway responsiveness to histamine, LTC4 and LTE4 in seven aspirin-sensitive subjects and 13 control asthmatic subjects, who were tolerant of aspirin." | 7.68 | Airway responsiveness to leukotriene C4 (LTC4), leukotriene E4 (LTE4) and histamine in aspirin-sensitive asthmatic subjects. ( Christie, PE; Lee, TH; Schmitz-Schumann, M; Spur, BW, 1993) |
"We wanted to investigate whether asthmatic subjects change their ventilatory pattern consistently when forced expiratory volume in one second (FEV1) has declined by at least 20% during bronchial histamine challenge, in order to assess whether respiratory pattern analysis can be used to monitor bronchial obstruction continuously." | 7.68 | Ventilatory pattern during bronchial histamine challenge in asthmatics. ( Gustafsson, PM; Strömberg, NO, 1993) |
"Histamine is an important mediator of allergic inflammation and bronchial hyperresponsiveness (BHR), a hallmark of asthma." | 7.68 | Plasma histamine and bronchial reactivity in allergic asthma. ( Bury, T; Corhay, JL; Louis, R; Radermecker, MF, 1993) |
"Interaction among mediators such as bradykinin (BK), histamine (H), and prostaglandin (PG) D2 may contribute to reduction in airway caliber in asthma." | 7.68 | Interactive effect of inhaled bradykinin with histamine and PGD2 in bronchial asthma. ( Church, MK; Gnanakumaran, G; Holgate, ST; Howarth, PH; Rajakulasingam, K, 1993) |
"We have studied the effects of histamine on the proliferation and the intracellular cyclic adenosine monophosphate (cAMP) levels of T-lymphocyte clones (TLC) generated from bronchoalveolar lavage fluid (BALF) or peripheral blood (PB) from healthy and asthmatic persons." | 7.68 | Heterogeneous effects of histamine on proliferation of lung- and blood-derived T-cell clones from healthy and asthmatic persons. ( Bast, A; Bruinier, B; Hol, BE; Jansen, HM; Krouwels, FH; Lutter, R; Out, TA; Wierenga, EA, 1993) |
"Bronchial reactivity was assessed in 66 children with bronchial asthma (aged 8-15 years) by provocation with histamine-HCl during a symptom-free period." | 7.68 | Respiratory resistance and transcutaneous PO2 during histamine provocation in children with bronchial asthma. ( Aberg, N; Bjure, J; Engström, I; Holmgren, D; Sixt, R, 1993) |
"To investigate the possible role of mast cell or basophil histamine release in mediating platelet-activating factor (PAF) airway obstruction, we studied the effect of inhaled PAF (30 micrograms, single dose) on plasma histamine, bronchial caliber, and leukocyte and platelet counts in six patients with mild or moderate allergic asthma (mean age, 27 +/- 1." | 7.68 | No increase in plasma histamine during PAF-induced airway obstruction in allergic asthmatics. ( Bury, T; Corhay, JL; Louis, R; Radermecker, M, 1993) |
"We attempted to determine the relationship of nasal polyps to histamine (HA) metabolism." | 7.68 | Histamine metabolism in nasal polyps. ( Abe, Y; Fukui, H; Harada, T; Imamura, I; Irifune, M; Matsunaga, T; Ogino, S, 1993) |
"The effects of theophylline on allergen-induced airway obstruction and bronchial hyperresponsiveness were investigated in allergic rabbits." | 7.68 | Modification of allergen-induced airway obstruction and bronchial hyperresponsiveness in the allergic rabbit by theophylline aerosol. ( Ali, S; Metzger, WJ; Mustafa, SJ, 1992) |
" We assayed urinary LTE4 in 17 normal subjects, 31 subjects with asthma without aspirin sensitivity, and 10 aspirin-sensitive subjects." | 7.68 | Urinary leukotriene E4 in bronchial asthma. ( Christie, PE; Hawksworth, RJ; Lee, TH; Smith, CM; Thien, FC, 1992) |
" To investigate the role of mast cells and eosinophils in the pathogenesis of nocturnal asthma, the plasma methylhistamine concentration, serum eosinophil cationic protein level and peak expiratory flow rate were measured 2-hourly for 24 h in 10 patients with nocturnal asthma and in 10 healthy control subjects." | 7.68 | Circulating histamine and eosinophil cationic protein levels in nocturnal asthma. ( Church, MK; Douglas, NJ; Fitzpatrick, MF; Holgate, ST; Mackay, T; Tai, PC; Walters, C, 1992) |
"Altogether 300 patients suffering from bronchial asthma were examined for serotonin metabolism, the kallikrein-kinin system and histamine." | 7.68 | [The role of serotonin, histamine and the kallikrein-kinin system in the pathogenesis of asphyxic attacks in bronchial asthma]. ( Fedoseev, GB; Goncharova, VA; Kachanova, TA; Razumovskaia, TL; Zhikharev, SS, 1992) |
"We evaluated the levels of bradykinin, albumin, TAME-esterase activity, histamine, PGD2 and LTC4 in bronchoalveolar lavage fluid from asthmatics and from patients with pneumonia, sarcoidosis, fibrosis, and chronic bronchitis." | 7.68 | Bradykinin and other inflammatory mediators in BAL-fluid from patients with active pulmonary inflammation. ( Baumgarten, CR; Brunnee, T; Dorow, P; Henning, R; Kunkel, G; Lehmkuhl, B; Schilling, W, 1992) |
"The effect of a prior histamine challenge on the bronchodilator response to salbutamol after spontaneous recovery of FEV1 to 95% of the prechallenge level was studied in two groups of asthmatic children." | 7.68 | Assessment of bronchodilatation after spontaneous recovery from a histamine challenge in asthmatic children. ( Duiverman, EJ; Kerrebijn, KF; Merkus, PJ; Quanjer, PH; Rooda, HM; van Essen-Zandvliet, EE, 1992) |
" To investigate the role of platelet activating factor (PAF) in the immediate asthmatic response, we examined the bronchial reactivity to histamine after administration of PAF to guinea-pigs or antigen challenge to passively sensitized guinea-pigs." | 7.68 | Platelet-activating factor (PAF) plays an important role in the immediate asthmatic response in guinea-pig by augmenting the response to histamine. ( Imanishi, N; Morooka, S; Uchida, M, 1992) |
" Administration of erythromycin to asthmatic patients in a dosage of 600 mg/d for 10 weeks reduced the bronchial hyperresponsiveness measured by histamine inhalation test." | 7.68 | Effect of erythromycin on bronchial hyperresponsiveness in patients with bronchial asthma. ( Miyatake, H; Satake, T; Suzuki, K; Takagi, K; Taki, F, 1991) |
"The purpose of this investigation was to study factors of importance for the degree of bronchial responsiveness and, furthermore, to evaluate the sensitivity, specificity and predictive value of a bronchial challenge test with histamine for the diagnosis of asthma in 495 randomly selected children and adolescents, aged 7-16 yrs, from Copenhagen, Rigshospitalet." | 7.68 | Sensitivity and specificity of the histamine challenge test for the diagnosis of asthma in an unselected sample of children and adolescents. ( Bach-Mortensen, N; Backer, V; Dirksen, A; Groth, S; Hansen, KK; Laursen, EM; Wendelboe, D, 1991) |
"A single oral dose of verapamil 80 mg was shown significantly to inhibit histamine-induced broncho-constriction in 8 out of 16 asthmatic subjects (maximum increase in PD20FEVHi 416%)." | 7.68 | Verapamil in the prophylaxis of bronchial asthma. Is the bronchoprotective effect related to the plasma level? ( Elsasser, S; Follath, F; Ha, HR; Imhof, E; Perruchoud, AP; Rosmus, B, 1991) |
"Plasma histamine, cortisol, epinephrine, cyclic adenosine monophosphate (cAMP), and leukocyte beta-adrenergic receptors were measured in asthmatic patients with (n = 7) and without (n = 10) nocturnal asthma at 4 PM and 4 AM and compared with those of normal subjects (n = 10)." | 7.68 | Plasma histamine, epinephrine, cortisol, and leukocyte beta-adrenergic receptors in nocturnal asthma. ( Ando, R; Cicutto, LC; Hill, MR; Martin, RJ; Surs, W; Szefler, SJ, 1991) |
"Tachyphylaxis to histamine was investigated in 16 children, aged 7-15 years, with mild asthma." | 7.68 | Repeated provocation tests in asthmatic children for testing tachyphylaxis to histamine. ( Gerritsen, J; Knol, K; Roorda, RJ; Schouten, JP; van Aalderen, WM, 1991) |
"We measured the concentration of inhaled histamine required to reduce the FEV1 by 20% (PC20) in seven asthmatic patients immediately following the inhalation of warm air (mean temperature +/- 1 SD, 21." | 7.68 | Effect of cold air on the bronchial response to inhaled histamine in patients with asthma. ( Cockcroft, DW; Dosman, JA; Hodgson, WC, 1991) |
"Bronchoalveolar lavage (BAL) fluid was evaluated for histamine and tryptase levels in 61 samples (46 samples from 24 atopic asthmatics, seven samples from seven patients with allergic rhinitis, and eight samples from eight normal volunteers)." | 7.68 | Elevated bronchoalveolar lavage fluid histamine levels in allergic asthmatics are associated with increased airway obstruction. ( Busse, WW; Calhoun, WJ; Jarjour, NN; Schwartz, LB, 1991) |
"A study was carried out to investigate whether an imbalance in the autonomic nervous system or release of histamine, or both, is responsible for the nocturnal increase in airflow obstruction in asthmatic children." | 7.68 | Nocturnal airflow obstruction, histamine, and the autonomic central nervous system in children with allergic asthma. ( Knol, K; Koëter, GH; Postma, DS; van Aalderen, WM, 1991) |
"Responsiveness to inhaled histamine and DL propranolol hydrochloride was measured in 31 adult asthmatics and compared with bronchoconstriction provoked by acute oral propranolol dosing (max 160 mg)." | 7.68 | Bronchoconstriction of the asthmatic airway by inhaled and ingested propranolol. ( Latimer, KM; Ruffin, RE, 1990) |
"Low levels of [3H]-dihydroergocryptine (DHE) (alpha adrenergic receptor) binding to peripheral blood mononuclear leukocytes from asthmatic subjects were significantly increased following incubation with histamine." | 7.68 | Effects of histamine on alpha adrenergic receptor expression on the lymphocytes of normal and asthmatic subjects. ( Easton, JG; Goldberg, BJ; Herman, FF; Kaplan, M; Lad, PM; Neidzin, H, 1990) |
"Airways responsiveness to leukotriene (LT) C4, LTD4, LTE4, histamine, and methacholine have been studied in eight asthmatic and six normal subjects." | 7.68 | Asthmatic airways have a disproportionate hyperresponsiveness to LTE4, as compared with normal airways, but not to LTC4, LTD4, methacholine, and histamine. ( Arm, JP; Crea, AE; Fong, CY; Hawksworth, RJ; Lee, TH; O'Hickey, SP; Spur, BW, 1990) |
"To determine whether bronchoconstriction induced by sulfur dioxide can be predicted by the airway response to inhaled histamine, we exposed on two days 46 patients with asthma to air or 0." | 7.68 | Relationship between the airway response to inhaled sulfur dioxide, isocapnic hyperventilation, and histamine in asthmatic subjects. ( Jörres, R; Magnussen, H; von Nieding, G; Wagner, HM, 1990) |
"Four patients with asthma caused by occupational exposure to tetrachlorophthalic anhydride (TCPA) had dust-challenge tests that used eight different levels of TCPA exposure." | 7.68 | Exposure-response relationships in asthma caused by tetrachlorophthalic anhydride. ( Newman Taylor, AJ; Venables, KM, 1990) |
"This study was carried out to determine leukocyte phospholipase A2 (PLA2) activity and plasma lysophosphatidylcholine (LPC) levels in normal subjects and in patients with asthma and rhinitis and to examine their relationship to airway sensitivity to histamine." | 7.68 | Increased leukocyte phospholipase A2 activity and plasma lysophosphatidylcholine levels in asthma and rhinitis and their relationship to airway sensitivity to histamine. ( Agrawal, KP; Gangal, SV; Gaur, SN; Gupta, S; Mehta, D, 1990) |
"While some studies have clearly shown that tachyphylaxis occurs in asthmatic subjects when challenged consecutively with inhaled histamine, others were unable to demonstrate this phenomenon." | 7.68 | Lack of tachyphylaxis to histamine in both moderate and mild asthmatic subjects. ( Finnerty, JP; Holgate, ST; Polosa, R, 1990) |
"Although some studies have clearly demonstrated tachyphylaxis to inhaled histamine in subjects with asthma, other studies have not." | 7.68 | Tachyphylaxis to inhaled histamine in asthma: its significance and relationship to basal airway responsiveness. ( Finnerty, JP; Holgate, ST; Polosa, R, 1990) |
"The relationship of airway cooling during exercise to changes in airway caliber, plasma histamine levels, and circulating basophils was investigated in eight allergic asthmatic and eight normal subjects." | 7.67 | Exercise and isocapnic hyperventilation-induced bronchoconstriction in asthma: relevance of circulating basophils to measurements of plasma histamine. ( Church, MK; Holgate, ST; Howarth, PH; Pao, GJ, 1984) |
"In 16 asymptomatic asthmatics a functional study was carried out under controlled conditions during histamine bronchial provocation test (HBPT) and after bronchodilation test with either SCH 1000 or fenoterol by evaluating both SRAW and the slope of the alveolar plateau of nitrogen washout curve (N2 ph III)." | 7.67 | Comparative effects of SCH 1000 and fenoterol after histamine-induced bronchoconstriction in asymptomatic asthmatics. ( Bracamente, M; De Coster, A; Esposito-Iacenna, V; Gigliotti, F; Scano, G; Sergysels, R; Stendardi, L, 1984) |
"In order to determine the shape of the dose-response curves of the human airways to bronchial challenge, changes in forced expiratory volume in one second (FEV1) after inhaled histamine were measured in 8 current asthmatic, 2 mildly asthmatic, and 10 normal subjects." | 7.67 | The shape of the dose-response curve to histamine in asthmatic and normal subjects. ( Salome, CM; Woolcock, AJ; Yan, K, 1984) |
" method were studied in 30 patients with various forms of bronchial asthma and 6 healthy subjects, and the reactivity of rosette--forming T-lymphocytes was determined after stimulation by asthmopent, histamine and acetylcholine." | 7.67 | [Effect of beta-adrenergic mimetics and histamine on the capacity of T-lymphocytes from asthmatic patients and healthy persons to form E-rosettes]. ( Bozhkov, B; Dimitrov, V; Kosturkov, G; Slavov, S, 1984) |
"Nonspecific bronchial reactivity, involving inhaled challenges with methacholine and histamine and treadmill exercise challenge, were compared in 2 groups of steroid-requiring asthmatic children (9 to 15 yr of age) distinguished on the basis of marked differences in their typical time course of clinical deterioration leading to in-hospital management." | 7.67 | Comparison of responsiveness to methacholine, histamine, and exercise in subgroups of asthmatic children. ( Bhagat, RG; Grunstein, MM, 1984) |
"The effect of increasing concentrations of inhaled sodium cromoglycate (SCG) (2, 10, 20 and 40 g/l) on histamine and methacholine bronchial reactivity was studied in nine patients with extrinsic bronchial asthma." | 7.67 | Sodium cromoglycate in histamine and methacholine reactivity in asthma. ( Patel, KR, 1984) |
"The inhibition of immediate allergen or histamine induced airflow obstruction by inhaled ketotifen, clemastine, sodium cromoglycate, and placebo was studied in two groups of asthmatic subjects." | 7.67 | Effect of antihistamines and antiallergic drugs on responses to allergen and histamine provocation tests in asthma. ( Davies, RJ; Gould, C; Ollier, S; Phillips, MJ, 1984) |
"The histamine level of whole blood and plasma in asthmatic patients was estimated by means of a simple, sensitive and specific method, which was developed to measure low histamine levels." | 7.67 | The determination of blood histamine in asthmatic patients with a simple and sensitive method. ( Aoki, T; Hoshi, S; Izumi, H; Mue, S; Sato, H; Takishima, T, 1984) |
"Inhalation histamine dose-response curves were constructed 15 minutes after inhalation of saline placebo or verapamil (4 mg) for eight patients with mild atopic asthma in a double blind, random manner." | 7.67 | Effects of calcium channel blockade on histamine induced bronchoconstriction in mild asthma. ( Banks, J; Davies, BH; Fennerty, A; Walters, EH, 1984) |
"The effect of 1 mg inhaled prazosin on bronchoconstriction induced by methoxamine was investigated in seven asthmatic subjects." | 7.67 | The action of prazosin and propylene glycol on methoxamine-induced bronchoconstriction in asthmatic subjects. ( Black, JL; Salome, C; Shaw, J; Yan, K, 1984) |
"When ingested in acid solution, the preservative sodium metabisulfite (MB) provokes asthma within minutes of ingestion in a proportion of asthmatic subjects." | 7.67 | The relationship of inhaled sulfur dioxide reactivity to ingested metabisulfite sensitivity in patients with asthma. ( Allen, DH; Castle, WD; Delohery, J; Simmul, R, 1984) |
"In the present study the concentrations of IgE and histamine were determined in gingival tissue of patients with asthma (N = 15), patients with periodontitis (N = 21) and healthy controls (N = 18)." | 7.67 | Gingival IgE and histamine concentrations in patients with asthma and in patients with periodontitis. ( Hyyppä, T, 1984) |
"Inhaled adenosine causes bronchoconstriction in asthmatic patients." | 7.67 | Adenosine-induced bronchoconstriction in asthma. Antagonism by inhaled theophylline. ( Cushley, MJ; Holgate, ST; Tattersfield, AE, 1984) |
" We assessed mast-basophiloid cell numbers and histamine levels with a sensitive histamine assay, lower limit of sensitivity, 25 pg/ml, in BAL fluid from normal individuals (n = 9) and compared these results to those obtained from patients with sarcoidosis (n = 31), idiopathic pulmonary fibrosis (IPF) (n = 8), and mild asthma (n = 7)." | 7.67 | Histamine levels in bronchoalveolar lavage from patients with asthma, sarcoidosis, and idiopathic pulmonary fibrosis. ( Kaliner, M; Rankin, JA; Reynolds, HY, 1987) |
"Spontaneous histamine release (SHR) from basophils by simple incubation at 37 degrees C for 60 minutes and histamine content of basophils were assessed in normal subjects, patients with asthma, and methacholine-sensitive subjects without asthma (NAMS)." | 7.67 | Spontaneous histamine release and histamine content in normal subjects and subjects with asthma. ( Akagi, K; Townley, RG, 1989) |
"A sulpyrin inhalation test was given to 13 patients with aspirin-induced asthma (AIA) and 8 patients with non-aspirin-induced asthma (non-AIA) to observe the changes in plasma histamine levels before and after challenges." | 7.67 | [The changes in plasma histamine levels after a sulpyrin inhalation test in asthmatic patients]. ( Adachi, M; Kokubu, F; Maeda, M; Okada, Y; Takahashi, T; Tanabe, Y; Tsuji, A, 1989) |
"Airway responsiveness to histamine and leukotriene E4 (LTE4) has been compared between five subjects with aspirin-induced asthma (AIA) and 15 asthmatic subjects without aspirin sensitivity (non-AIA)." | 7.67 | Airway responsiveness to histamine and leukotriene E4 in subjects with aspirin-induced asthma. ( Arm, JP; Lee, TH; O'Hickey, SP; Spur, BW, 1989) |
"We measured the plasma histamine concentration in patients with bronchial asthma by the post-column derivatization method developed by Yamatodani." | 7.67 | [Application of HPLC to measurement of plasma histamine in bronchial asthma]. ( Hasegawa, T; Satake, T; Suzuki, R; Takagi, K; Watanabe, T; Yamaki, K; Yamatodani, A, 1989) |
"The effect of two consecutive histamine inhalation challenges on airways responsiveness was assessed in a group of eight nonsmoking nonmedicated asthmatics aged 19-27 yr." | 7.67 | Airways responsiveness determined by consecutive histamine challenges in asymptomatic asthmatics. ( Burki, NK; Küng, M; Scott, GC, 1989) |
"In order to elucidate the working mechanisms of immunotherapy (IT), the in vitro productions of histamine, prostaglandin E2 (PGE2) and leukotriene C4 (LTC4) were studied in 18 newly diagnosed and 20 hyposensitized (greater than 2 yr) asthmatic children." | 7.67 | The effect of immunotherapy on the in vitro productions of histamine, prostaglandin E2 and leukotriene C4 in asthmatic children. ( Hsieh, KH; Wang, JY, 1989) |
"4 mg salbutamol on the impedance of the respiratory system was studied in 25 asthmatic subjects after histamine-induced bronchoconstriction." | 7.67 | Response localization of the pharmacological agents histamine and salbutamol along the respiratory system by forced oscillations in asthmatic subjects. ( Polko, AH; Visser, BF; Wouters, EF, 1989) |
"The airway responses to histamine, exercise and ultrasonically nebulized hypertonic saline have been compared in ten asthmatic patients." | 7.67 | Airway responses to hypertonic saline, exercise and histamine challenges in bronchial asthma. ( Belcher, NG; Lee, TH; Rees, PJ, 1989) |
"The effects of cimetidine and ranitidine on the bronchial reactivity in the group of 10 patients with atopic bronchial asthma are presented." | 7.67 | Comparison of the effects of cimetidine and ranitidine in histamine provocation tests in atopic asthma. ( Hofman, J; Michalska, I; Rutkowski, R, 1989) |
"Airway reactivity to histamine was determined in a group of non-asthmatic and asthmatic patients prior to thoracotomy." | 7.67 | Human isolated bronchial muscle preparations from asthmatic patients: effects of indomethacin and contractile agonists. ( Benveniste, J; Brink, C; Cerrina, J; Haye-Legrande, I; Labat, C; Raffestin, B, 1989) |
" We determined the decrease in maximal expiratory flow rates (Vmax) from partial and maximal flow-volume curves in seven asthmatic subjects after inhalation of aerosols of histamine or leukotriene C4 (LTC4) while breathing air or a mixture of 80% helium and 20% oxygen (He/O2)." | 7.67 | Localization of the site of the bronchoconstrictor effects of leukotriene C4 compared with that of histamine in asthmatic subjects. ( Austen, KF; Corey, EJ; Drazen, JM; Ingram, RH; Lafleur, JE; Pichurko, BM; Sperling, RI, 1989) |
"The relative bronchoconstricting potencies of leukotriene E4 (LTE4) methacholine and histamine have been compared in asthmatic and normal subjects." | 7.67 | The relative responsiveness to inhaled leukotriene E4, methacholine and histamine in normal and asthmatic subjects. ( Arm, JP; Lee, TH; O'Hickey, SP; Rees, PJ; Spur, BW, 1988) |
"The disparity between the activation of mast cells in the airways of patients with allergic asthma and the lack of efficacy of H1-antihistamines in asthma therapy has been difficult to reconcile." | 7.67 | Astemizole and other H1-antihistaminic drug treatment of asthma. ( Emanuel, MB; Holgate, ST; Howarth, PH, 1985) |
"To assess the role of histamine as a mediator in the response to exercise and isocapnic hyperventilation of cold air (IHCA) in asthma, we studied nine asthmatic subjects, age 13 to 25 years." | 7.67 | Effect of terfenadine on the response to exercise and cold air in asthma. ( Chernick, V; Montgomery, M; Pasterkamp, H; Poynter, A; Wiebicke, W, 1988) |
"To investigate possible mediator interaction in asthma, the effect of inhaled leukotriene (LT) C4 on bronchoconstriction provoked by histamine and prostaglandin (PG) D2 was studied in nine asthmatic subjects." | 7.67 | Interaction of inhaled LTC4 with histamine and PGD2 on airway caliber in asthma. ( Holgate, ST; Phillips, GD, 1989) |
"In 12 asthmatic children, aged 8-14 years, we investigated the possibility of using a provocation concentration of histamine (PC) causing a 10% or 15% fall in baseline forced expiratory volume in 1 sec (FEV1), instead of a PC20 histamine, in the assessment of bronchial hyperreactivity." | 7.67 | The reproducibility and agreement of three indices of airway responsiveness to histamine in asthmatic children. ( Gerritsen, J; Knol, K; Koëter, GH; Postma, DS; van Aalderen, WM; van der Weele, LT, 1989) |
"To determine whether refractoriness to histamine induced bronchoconstriction occurs, 20 asthmatic subjects aged 19-50 years were tested." | 7.67 | Refractory period following bronchoconstriction provoked by histamine in asthmatic subjects. ( Avery, AJ; Connolly, MJ; Hendrick, DJ; Stenton, SC; Walters, EH, 1989) |
"The relation between airway responsiveness to propranolol and histamine was studied in 32 asthmatic children." | 7.67 | Propranolol inhalation challenge in relation to histamine response in children with asthma. ( Gerritsen, J; Knol, K; Koëter, GH; Vander Weele, LT, 1988) |
"There is widespread belief that methacholine responsiveness in asthmatic subjects is closely related to histamine responsiveness, and that the two agents may be used interchangeably in the measurement of non-specific bronchial responsiveness (NSBR)." | 7.67 | The relationship between bronchial responsiveness to methacholine and bronchial responsiveness to histamine in asthmatic subjects. ( Avery, AJ; Connolly, MJ; Hendrick, DJ; Walters, EH, 1988) |
"Adenosine, when it is administered by inhalation to asthmatic subjects, is a potent bronchoconstrictor, although its mechanism of action is not known." | 7.67 | Adenosine-induced bronchoconstriction in asthma: role of mast cell-mediator release. ( Cushley, MJ; Holgate, ST, 1985) |
"The adenylate cyclase response to histamine was measured in lymphocyte membranes of allergic asthmatic patients and healthy control subjects, just before and 24 h after inhalation challenge with house dust mite allergen." | 7.67 | Reduced adenylate cyclase responsiveness to histamine in lymphocyte membranes of allergic asthmatic patients after allergen challenge. ( de Vries, K; Folkers, B; Kauffman, HF; Koëter, GH; Meurs, H; Timmermans, A, 1985) |
"Adenosine by inhalation causes bronchoconstriction in asthmatic but not in normal subjects by an undefined mechanism." | 7.67 | Adenosine-induced bronchoconstriction in asthma. Role of parasympathetic stimulation and adrenergic inhibition. ( Cushley, MJ; Holgate, ST; Mann, JS, 1985) |
"Challenges with ouabain and histamine were performed a week apart in 10 patients with asthma and 5 normal subjects." | 7.67 | Airway responses to inhaled ouabain in subjects with and without asthma. ( Agrawal, KP; Hyatt, RE; Imber, WE; Krell, WS; Reed, CE, 1986) |
"The bronchoconstrictor activity of an aerosol of leukotriene E4(LTE4) was compared with that of histamine in 5 normal and in 6 asthmatic subjects to define the relative potency of LTE4 between the groups using 3 indices of airway response." | 7.67 | Bronchoconstrictor effects of leukotriene E4 in normal and asthmatic subjects. ( Austen, KF; Corey, EJ; Davidson, AB; Drazen, JM; Ingram, RH; Lee, TH; McFadden, ER; Scanlon, PD; Solway, J, 1987) |
"Histamine-binding proteins have been isolated from healthy subjects and patients with endogenous bronchial asthma." | 7.67 | Histamine binding proteins identified in healthy subjects and asthmatic patients. ( Liebhart, E; Liebhart, J; Małolepszy, J; Szeliga, W; Zak-Nejmark, T, 1986) |
"Tachyphylaxis occurs to repeated challenges with inhaled histamine but not with inhaled acetylcholine in asthmatic subjects." | 7.67 | Histamine bronchoconstriction reduces airway responsiveness in asthmatic subjects. ( Manning, PJ; O'Byrne, PM, 1988) |
"Both exercise and histamine inhalation cause bronchoconstriction in asthmatic subjects." | 7.67 | Exercise refractoriness after histamine inhalation in asthmatic subjects. ( Hamielec, CM; Manning, PJ; O'Byrne, PM, 1988) |
"The effects of various doses of inhaled MgSO4 on the histamine bronchoprovocation test were studied in nine asthmatics in clinical remission (FEV1 greater than 80% of predicted)." | 7.67 | Dose-related effect of inhaled magnesium sulfate on histamine bronchial challenge in asthmatics. ( Bucca, C; Caria, E; Rolla, G, 1988) |
"This study was undertaken in order to assess the neural drive to the respiratory muscles and the inspiratory neuromuscular coupling in patients with bronchial asthma during histamine-induced bronchoconstriction." | 7.67 | Changes in neural drive (EMGd) and neuromuscular coupling during histamine-induced bronchoconstriction in patients with asthma. ( Arcangeli, P; Duranti, R; Gigliotti, F; Gorini, M; Scano, G; Spinelli, A, 1988) |
"We investigated immediate and late changes in airway responsiveness to histamine, after bronchoconstriction due to exercise combined with inhalation of cold air, in ten asthmatic subjects who came on six days." | 7.67 | Bronchoconstriction due to exercise combined with cold air inhalation does not generally influence bronchial responsiveness to inhaled histamine in asthmatic subjects. ( Cartier, A; Ghezzo, H; Malo, JL; Martin, RR; Tessier, P, 1988) |
"The relation between the pathochemical phase and the histaminergic reactivity of the effector structures in asthmatic patients was studied." | 7.67 | [The blood histamine level of patients with bronchial asthma and their skin vascular reaction to histamine]. ( Kosturkov, G; Vŭlcheva, T, 1988) |
"The effects of repeated exercise-induced bronchospasm on nonspecific (nonallergenic) bronchial responsiveness (NSBR) to histamine were studied in 12 asthmatic patients (6 F, 6 M)." | 7.67 | Bronchial responsiveness to histamine after repeated exercise-induced bronchospasm. ( Boulet, LP; Legris, C; Turcotte, H, 1987) |
"The reproducibility of the changes in FEV, induced by inhalation of histamine, was studied in adult asthmatics." | 7.67 | Reproducibility of histamine inhalation in asthmatics. ( Bundgaard, A; Schmidt, A, 1986) |
"Nine adult asthmatics were challenged with histamine four times during the same day, at 07." | 7.67 | Histamine challenge in asthmatics at 07.00-12.00-17.00 and 22.00 h. ( Andersen, KK; Bundgaard, A, 1986) |
"The immediate changes in regional ventilation and pulmonary blood flow were studied in seventeen adults with perennial asthma and in two control persons, who were challenged by histamine inhalation (histamine induced asthma (HIA))." | 7.67 | Regional V/Q changes in asthmatics after histamine inhalation. ( Bundgaard, A; Munkner, T, 1986) |
"The predictive value of a bronchial challenge with histamine was determined in a prospective survey on a population with a high prevalence of asthma (0." | 7.67 | Bronchial histamine challenge in the diagnosis of asthma. The predictive value of changes in airway resistance determined by the interrupter method. ( Frølund, L; Holstein-Rathlou, NH; Madsen, F; Svendsen, UG; Weeke, B, 1986) |
"Using a sensitive single isotope enzymatic assay we measured bronchoalveolar lavage (BAL) fluid histamine in asymptomatic normal (nonallergic), allergic rhinitic, and allergic asthmatic subjects." | 7.67 | Elevated bronchoalveolar lavage fluid histamine levels in allergic asthmatics are associated with methacholine bronchial hyperresponsiveness. ( Casale, TB; Hunninghake, GW; Metzger, WJ; Richerson, HB; Trapp, S; Wood, D; Zavala, D, 1987) |
"Factors that influence the time necessary for complete recovery of FEV1 after inhaling histamine were analysed in forty-five children with asthma." | 7.67 | Recovery of FEV1 after histamine challenge in asthmatic children. ( Akkerboom, HJ; Gerritsen, J; Knol, K; Koëter, GH, 1987) |
"Histamine inhalation provocation tests were performed in 18 asymptomatic asthmatic patients with progressively increasing doses of a pressurized aerosol of histamine phosphate." | 7.67 | Inspiratory impedance during histamine-induced bronchoconstriction in patients with bronchial asthma. ( Duranti, R; Gigliotti, F; Gorini, M; Lo Conte, C; Scano, G; Scibilia, MR; Spinelli, A, 1987) |
"The bronchoconstriction induced by repeated histamine inhalation tests was studied in eight mild stable asthmatic subjects to determine whether histamine tachyphylaxis occurs in asthmatics." | 7.67 | Tachyphylaxis to inhaled histamine in asthmatic subjects. ( Jones, GL; Manning, PJ; O'Byrne, PM, 1987) |
"To study the ability of cutaneous mast cells to degranulate in urticaria-prone patients, subjects were skin tested with the known mast cell degranulator, codeine sulfate." | 7.67 | Discrimination between urticaria-prone and other allergic patients by intradermal skin testing with codeine. ( Cohen, RW; Rosenstreich, DL, 1986) |
"To study the effect of inhaled clonidine on broncho-obstruction in asthmatics, 10 patients with extrinsic asthma were broncho-provoked twice with an allergen that had been shown to give positive skin prick test results." | 7.67 | The effect of inhaled clonidine in patients with asthma. ( Andersson, RG; Ekström, T; Lindgren, BR, 1986) |
" In order to evaluate the relative contribution of vagal and non-vagal afferences to increasing neural drive to the respiratory muscles in 14 asymptomatic asthmatic patients known to be responsive (decrease in FEV1 greater than 20% of the control values) to previous bronchial provocation test (BPT) with aerosolized histamine, we evaluated FEV1, breathing pattern and neuromuscular drive, as assessed by mouth occlusion pressure (PO." | 7.67 | Effects of histamine and reproterol inhalation on mouth occlusion pressure in patients with bronchial asthma. ( Arcangeli, P; Duranti, R; Emmi, L; Gigliotti, F; Lo Conte, C; Scano, G; Spinelli, A; Stendardi, L; Turco, R, 1986) |
"Histamine inhalation challenge was performed in 32 asthmatic children aged 6 through 13, 20 control children aged 8 through 14, and 16 control adults aged 24 through 37 years." | 7.67 | [Evaluation of the bronchial provocation test with histamine in asthmatic children]. ( Azcárate, MJ; Salazar, M; Vázquez Cordero, C, 1986) |
"Asthma was provoked by histamine inhalation in five children in order to study the hypoxaemia that might ensue and the underlying ventilation-perfusion (VA/Q) mismatching." | 7.67 | Histamine-induced asthma in children: effects on the ventilation-perfusion relationship. ( Freyschuss, U; Hedenstierna, G; Hedlin, G, 1985) |
"Nonspecific bronchial reactivity to exercise and histamine was measured in nine children with asthma before and within nine days after allergen inhalation." | 7.67 | Increased bronchial responsiveness to exercise and histamine after allergen challenge in children with asthma. ( Godfrey, S; Mussaffi, H; Springer, C, 1986) |
"In a group of aspirin-sensitive asthmatics we studied skin weal and flare responses to intradermal injections of compound 48/80 and histamine during oral aspirin (ASA) provocation and after ASA "desensitisation"." | 7.67 | The effect of aspirin during aspirin "desensitisation" on compound 48/80 and histamine-induced skin responses in aspirin-sensitive asthmatics. ( Grzelewska-Rzymowska, I; Kowalski, ML; Rozniecki, J; Szmidt, M, 1985) |
"In order to investigate the role of histamine in the late asthmatic reaction (LAR) following house-dust mite (HDM) inhalation, we studied, with hourly intervals, urinary N tau-methylhistamine (an important metabolite of histamine) in 14 allergic asthmatic patients before and after broncho provocation with HDM." | 7.67 | Histamine in late asthmatic reactions following house-dust mite inhalation. ( Beaumont, F; de Monchy, JG; de Vries, K; Kauffman, HF; Keyzer, JJ, 1985) |
"Twenty seven aspirin sensitive asthmatic patients were studied to determine the relationship between non-specific bronchial responsiveness to inhaled histamine and the degree of sensitivity to aspirin (aspirin threshold dose)." | 7.67 | Bronchial hyperreactivity to histamine in aspirin sensitive asthmatics: relationship to aspirin threshold and effect of aspirin desensitisation. ( Grzelewska-Rzymowska, I; Kowalski, ML; Rozniecki, J; Szmidt, M, 1985) |
"The effect of intravenous infusion of dipyridamole on histamine- and adenosine-induced bronchoconstriction was studied in 6 normal and 6 allergic asthmatic subjects." | 7.67 | The effect of dipyridamole on histamine- and adenosine-induced bronchoconstriction in normal and asthmatic subjects. ( Cushley, MJ; Holgate, ST; Tallant, N, 1985) |
"The effects of histamine, antihistamines, isoproterenol and theophylline on the expressions of Fc and complement (C') receptors on the polymorphonuclear leukocytes (PMN's) were studied in 40 asthmatic children." | 7.66 | The effects of histamine, antihistamines, isoproterenol and theophylline on the Fc and complement receptor functions of polymorphonuclear leukocytes in asthmatic children. ( Hsieh, KH, 1981) |
"The bronchodilatory response of three beta 2-agonists (fenoterol, salbutamol, and terbutaline), administered by a metered aerosol inhaler, was assessed in 19 asthmatic children after histamine-induced bronchoconstriction." | 7.66 | Mode of action of bronchodilating drugs on histamine-induced bronchoconstriction in asthmatic children. ( Duquenne, D; Geubelle, F; Kraemer, R; Mossay, C, 1981) |
"Studies using the guinea pig ileum bioassay technique have previously shown that patients with either asthma or chronic bronchitis have increased amounts of histamine in their sputum." | 7.66 | Histamine content of sputum from patients with asthma and chronic bronchitis. ( Bryant, DH; Pui, A, 1982) |
"The increased plasma-histamine levels observed after provocation of asthmatic subjects with antigen or exercise may result from the release of this granule-associated mediator from either mast cells or basophil leucocytes." | 7.66 | The role of basophils in asthma. I. Sodium cromoglycate on histamine release and content. ( Church, MK, 1982) |
"In 18 clinically stable asthmatic patients histamine inhalation challenges were performed with a Wright's nebuliser and tidal volume breathing for two minutes on two to four occasions for each subject at a maximum interval of two weeks." | 7.66 | Histamine dose-response curves in asthma: reproducibility and sensitivity of different indices to assess response. ( Dehaut, P; Malo, JL; Martin, RR; Rachiele, A, 1983) |
"Arterial plasma histamine concentrations were measured after exercise in 10 subjects with extrinsic atopic asthma, 10 who were non-atopic and non-asthmatic and seven who were atopic but non-asthmatic, by a single isotope radioenzymatic assay." | 7.66 | Plasma histamine in asthmatic and control subjects following exercise: influence of circulating basophils and different assay techniques. ( Davies, RJ; Moodley, I; Morgan, DJ; Phillips, MJ, 1983) |
"Significant increase in the maximum post-exercise values of plasma histamine (PH), whole blood histamine (WBH) and neutrophil chemotactic factor (NCF) occurred in arterial blood within the first hour after exercise in asthmatic patients." | 7.66 | Histamine, neutrophil chemotactic factor and circulating basophil levels following exercise in asthmatic and control subjects. ( Davies, RJ; Elliott, EV; Moodley, I; Morgan, DJ; Phillips, MJ, 1982) |
"A study to determine whether the bronchoconstriction induced by low concentration of sulfur dioxide in subjects with asthma decreases with repeated exposure was undertaken." | 7.66 | Tolerance to sulfur dioxide-induced bronchoconstriction in subjects with asthma. ( Bethel, RA; Boushey, HA; Epstein, J; Nadel, JA; Sheppard, D, 1983) |
"Standardized histamine provocations were repeated during remission on 10 atopic bronchial asthmatics, at 14 days (short-term) and after more than 12 months (long-term)." | 7.66 | Short-term and long-term variation in bronchial response to histamine in asthmatic patients. ( Lindholm, NB; Löwhagen, O, 1983) |
"Nine patients with extrinsic bronchial asthma were challenged with increasing doses of histamine until there was a 20% fall in the forced expiratory volume in one second (FEV1)." | 7.66 | Arterial oxygen changes in asthmatics following histamine. ( Chapman, TT, 1980) |
"Four workers from a recently established vanadium pentoxide refinery in Western Australia presented with green discoloration of the tongue, upper respiratory symptoms, and asthma." | 7.66 | Asthma caused by occupational exposure to vanadium compounds. ( Musk, AW; Tees, JG, 1982) |
"The authors studied variations in histamine and serotonin levels in whole blood, in ten asthmatics with bronchospasm induced by running." | 7.66 | [Histamine and serotonin levels in exercise induced bronchospasm in asthmatics (author's transl)]. ( Aubry, JP; Cheymol, G; Dry, J; Pradalier, A, 1980) |
"We have prospectively examined in 51 patients the relationship between the level of airway responsiveness to histamine and methacholine and the minimum medications required to control asthma." | 7.66 | Airway responsiveness to histamine and methacholine: relationship to minimum treatment to control symptoms of asthma. ( Frith, PA; Hargreave, FE; Juniper, EF, 1981) |
"In order to determine the effect of drugs on bronchial hyperreactivity in subjects with asthma, 12 atopic asthmatic volunteers underwent bronchial challenge with either histamine or methacholine on three separate days." | 7.66 | Effect of aerosol and oral fenoterol on histamine and methacholine challenge in asthmatic subjects. ( Salome, CM; Schoeffel, RE; Woolcock, AJ, 1981) |
" Venous plasma histamine and catecholamines were measured in stable asthmatic subjects by a recently developed specific and sensitive radioenzymatic assay." | 7.66 | Plasma histamine and catecholamines in stable asthmatic subjects. ( Barnes, PJ; Brown, MJ; Ind, PW, 1982) |
"Histamine inhalation provocation-tests were performed in twenty-two young asthmatics with normal lung-function tests with progressive, increasing doses of a pressurized aerosol of histamine phosphate." | 7.66 | Site of action of inhaled histamine in asymptomatic asthmatic patients. ( Bracamonte, M; de Coster, A; Scano, G; Sergysels, R; Stendardi, L, 1982) |
"We examined the effects of pharmacologic antagonists on the bronchial response to inhaled histamine in 11 normal and 11 asthmatic subjects." | 7.66 | Histamine dose-response relationships in normal and asthmatic subjects. The importance of starting airway caliber. ( Chung, KF; Keyes, SJ; Morgan, B; Snashall, PD, 1982) |
"A standardized bronchial histamine challenge was performed in 423 patients presenting with 1) asthma, 2) rhinitis, 3) asthma and rhinitis 4) rhinitis with cough or 5) chronic cough alone." | 7.66 | Bronchial responsiveness to histamine and allergen in patients with asthma, rhinitis, cough. ( Stevens, WJ; Vermeire, PA, 1980) |
"Histamine inhalation tests were performed in 12 asthmatic patients using a 2-min tidal breathing inhalation technique." | 7.66 | Repeated histamine inhalation tests in asthmatic patients. ( Alpers, JH; Crockett, AJ; Hamilton, R; Ruffin, RE, 1981) |
" Venous plasma histamine was measured by a specific and sensitive radioenzymatic assay in seven male extrinsic asthmatic and six age-matched non-atopic non-asthmatic male subjects during exercise and voluntary isocapnic hyperventilation." | 7.66 | Venous plasma histamine in exercise- and hyperventilation-induced asthma in man. ( Barnes, PJ; Brown, MJ, 1981) |
"The aim of the present study was to determine if the measurement of the slope of teh histamine dose-response curve (bronchial reactivity) could provide useful information on the clinical state of asthma." | 7.66 | Histamine dose-response curves in asthma: relevance of the distinction between PC20 and reactivity in characterising clinical state. ( Beaupré, A; Malo, JL, 1981) |
"Although histamine plays an important role in the pathophysiology of asthma through stimulation of H1 receptors, H1 antagonists are of only limited use in this disease when given orally." | 7.66 | Modulation of histamine-induced bronchoconstriction with inhaled, oral, and intravenous clemastine in normal and asthmatic subjects. ( Hartmann, V; Holle, JP; Magnussen, H; Schüler, E, 1981) |
"In vitro preparations of trachea isolated from normal and asthmatic guinea pigs were used to measure their maximum contractile response to histamine challenge and to determine spontaneous relaxation of smooth muscle of the airway." | 7.66 | Effects of ketamine and halothane on normal and asthmatic smooth muscle of the airway in guinea pigs. ( Aldrete, JA; Cabanas, A; Souhrada, JF, 1980) |
"Tracheal smooth muscle (TSM) from an ovalbumin sensitized canine model of allergic asthma showed hypersensitivity and hyper-reactivity to histamine (H) when compared to that from littermate controls in vitro." | 7.66 | Histamine pharmacology in airway smooth muscle from a canine model of asthma. ( Antonissen, LA; Bergen, J; Kepron, W; Kroeger, EA; Mitchell, RW; Stephens, NL, 1980) |
"14C-histamine was administered intrabronchially to asthmatic patients and controls." | 7.66 | Metabolism of 14C-histamine given intrabronchially to asthmatic patients. ( Bergmark, J; Granerus, G; Löwhagen, O; Thiringer, G, 1980) |
"In 15 asthmatic subjects, flow volume loops were recorded before and after quantitative nebulization of increasing concentration of histamine and allergen, until a threshold response (-delta FEV1 > 10%) was obtained." | 7.66 | Effect of an H1 blocker, chlorpheniramine, on inhalation tests with histamine and allergen in allergic asthma. ( Popa, VT, 1980) |
" Hyperinflation was provoked in two asthmatic and three normal subjects by progressively doubling doses of histamine." | 7.66 | Tonic inspiratory muscle activity as a cause of hyperinflation in histamine-induced asthma. ( Bryan, AC; Muller, N; Zamel, N, 1980) |
"In order to determine if there is a relationship among arterial histamine levels, state of disease activity, and the magnitude and site of obstruction in exercise-induced asthma, we recorded airway resistance, lung volumes, spirometry, and density dependence of maximum expiratory flow before and after an exercise challenge in 17 asymptomatic individuals." | 7.66 | Magnitude and site of airway response to exercise in asthmatics in relation to arterial histamine levels. ( Ingram, RH; McFadden, ER; Soter, NA, 1980) |
"Eight subjects with asthma underwent bronchial challenge with histamine and methacholine." | 7.66 | Comparison of bronchial reactivity to histamine and methacholine in asthmatics. ( Salome, CM; Schoeffel, RE; Woolcock, AJ, 1980) |
"The underlying biochemical and physiological changes responsible for remarkable airway hyperreactivity to histamine and other non-specific stimuli in asthmatics are poorly understood." | 7.66 | Is airway hyperactivity in asthma due to histamine H2-receptor deficiency? ( Chand, N, 1980) |
"The preventive effect of ketotifen, a new drug with anti-histaminic and antiallergic properties, on histamine-induced bronchoconstriction was studied by open assessment in twenty-four adult patients with extrinsic asthma." | 7.66 | Preventive effect of ketotifen, a new antiallergic agent, on histamine-induced bronchoconstriction in asthmatics. ( Mattson, K; Nikander-Hurme, R; Poppius, H, 1979) |
"The investigation of 10 patients with allergic asthma showed histamine levels of 79." | 7.66 | [Histamine levels in blood of patients with allergic bronchial asthma (author's transl)]. ( Koppermann, G; Morr, H, 1979) |
"The contents of histamine and cyclic nucleotides were studied in leukocytes before and after a bronchoprovocation test on patients with extrinsic asthma." | 7.66 | Changes in histamine and cyclic nucleotide levels after bronchoprovocation in patients with extrinsic asthma. ( Andersson, RG; Brundin, A; Lindgren, BR, 1978) |
"Nine asthmatic patients with a mean age of 14 yr received bronchial challenges with histamine and methacholine." | 7.66 | Bronchial hyperreactivity to histamine and methacholine in asthmatic children after inhalation of SCH 1000 and chlorpheniramine maleate. ( Kattan, M; Levison, H; Orange, RP; Woenne, R, 1978) |
"Levels of airways hyperreactivity, as indexed by methacholine and histamine thresholds, were determined for hospitalized asthmatic patients using the serial concentration, constant-breath method." | 7.66 | Methacholine and histamine inhalation challenges in asthma: relationships to age of onset, length of illness, and pulmonary functions. ( Fukuhara, J; Kinsman, RA; Spector, SL; Staudenmayer, H; Westmoreland, C, 1979) |
"Histamine metabolism was investigated in patients with intrinsic asthma, during the acute phase and in remission, by determination of the urinary excretion of histamine metabolites." | 7.66 | Studies on histamine metabolism in intrinsic bronchial asthma. ( Granerus, G; Löwhagen, O; Wetterqvist, H, 1979) |
"Fifty asthmatic children were tested with both a standardized treadmill exercise and a histamine inhalation on 2 separate days." | 7.66 | Comparative study of histamine and exercise challenges in asthmatic children. ( Kattan, M; Keens, TG; Levison, H; Mellis, CM, 1978) |
"In order to examine the hypothesis that bronchial reactivity to non-specific constrictor stimuli is influenced by the resting tone of the bronchial smooth muscle, the airway responses to inhaled histamine solution and inhaled isoprenaline were measured in 19 patients with airway obstruction." | 7.66 | Bronchial responsiveness to inhaled histamine and isoprenaline in patients with airway obstruction. ( Benson, MK, 1978) |
"Controlled standardised histamine inhalation tests were carried out in 21 asthmatics to determine the degree of non-specific bronchial hyperreactivity with and without prior treatment with several anti-asthmatic drugs." | 7.65 | Protective effect of drugs on histamine-induced asthma. ( Cockcroft, DW; Hargreave, FE; Killian, DN; Mellon, JJ, 1977) |
"The respiratory threshold to histamine and the plasma cyclic adenosine monophosphate (AMP) every 5 min for 40 min after subcutaneous epinephrine were determined in 21 children with moderate bronchial asthma who were without symptoms at the time of study." | 7.65 | Correlation between increased bronchial responsiveness to histamine and diminished plasma cyclic adenosine monophosphate response after epinephrine in asthmatic children. Diminished plasma cyclic adenosine monophosphate response after epinephrine in moder ( Aksnes, L; Apold, J, 1977) |
"Increased bronchial sensitivity to inhaled histamine in asthma is well known." | 7.65 | Decreased H2 histamine response of granulocytes of asthmatic patients. ( Busse, WW; Sosman, J, 1977) |
" Cromolyn sodium aerosols prevented 48/80 induced asthma but did not influence histamine induced broncho-constriction." | 7.65 | Effect of cromolyn sodium and of daily exposure to compound 48/80 on experimental asthma. ( Ambrus, LC; Thurber, L, 1975) |
"Histamine is thought to be one of the primary mediators of the airways response in allergic asthma." | 7.65 | Effects of intravenous histamine on pulmonary mechanics in nonasthmatic and asthmatic subjects. ( Brown, R; Ingram, RH; McFadden, ER; Wellman, JJ, 1977) |
"Bronchial reactivity to prostaglandins F2alpha (PGF2alpha), E2 (PGE2) and histamine has been studied in 27 patients with aspirin-sensitive asthma and in 28 asthmatics without this sensitivity." | 7.65 | Bronchial reactivity to prostaglandins F2alpha, E2, and histamine in different types of asthma. ( Nizankowska, E; Nizankowski, R; Szczeklik, A, 1977) |
"Under carefully controlled conditions, seven aspirin-intolerant asthmatic patients were challenged with oral aspirin and experienced respiratory tract reactions with a decline in forced expiratory volume in 1 sec (FEV1) ranging from 26 to 64%." | 7.65 | Oral aspirin challenges in asthmatic patients: a study of plasma histamine. ( Arroyave, CM; Bhat, KN; Stevenson, DD; Tan, EM, 1976) |
"Plasma, whole blood, and urinary histamine levels have been determined in 64 normal subjects, in 10 patients with severe asthma, and in 10 control patients with other illnesses." | 7.65 | Histamine levels in plasma, blood, and urine in severe asthma, and the effect of corticosteroid treatment. ( Bruce, C; Seaton, A; Taylor, WH; Weatherstone, R, 1976) |
"Bronchial provocation tests using aerosolized serially diluted histamine and methacholine were given to nearly 200 asthmatics." | 7.65 | A comparison of methacholine and histamine inhalations in asthmatics. ( Farr, RS; Spector, SL, 1975) |
"The absolute counts on basophil and eosinophil leucocytes, percentage of vacuolated eosinophil cells and whole blood histamine were determined in 30 controls and 34 patients with bronchial asthma." | 7.65 | Cytomorphological variations and blood histamine in bronchial asthma. ( Baldwa, VS; Chopra, YM; Goyal, RK; Sehgal, PP; Singh, J; Varandani, N, 1976) |
"Histamine challenges were carried out by tidal breathing method at entry, and at Days 4, 8, 22, 36, and 40." | 6.69 | Effects of theophylline on tolerance to the bronchoprotective actions of salmeterol in asthmatics in vivo. ( Cheung, D; de GOEIJ, JA; de GRAAFF, CS; Steen, H; Sterk, PJ; Wever, AM, 1998) |
"Pathogenesis of non-atopic bronchial asthma remains still an open question." | 6.69 | [Bronchial hyperreactivity to histamine and levels of serum eosinophil cationic protein in patients with non-atopic asthma]. ( Dobek, R; Liebhart, E; Litwa, M; Małolepszy, J; Medrala, W; Wolańczyk-Medrala, A; Wrzyszcz, M; Wytrychowski, K, 1999) |
" In each subject, dose-response curves for the effects on forced expiratory volume in one second (FEV1) of serially doubling doses of inhaled histamine were obtained on three different days, 15 min after pretreatment with either methoxamine (10 mg) or duplicated placebo." | 6.68 | Effects of pretreatment with inhaled methoxamine on bronchial responses to histamine in asthmatic subjects. ( Dall'Ava-Santucci, J; Dinh-Xuan, AT; Lockhart, A; Monchi, M; Phan-Puibaraud, TT; Regnard, J, 1995) |
"Atopic dermatitis and bronchial asthma are genetically dependent diseases, connected with an over-synthesis of IgE antibodies, in which a chronic inflammation is characteristic for their pathogenesis." | 6.68 | [Pulmonary function tests and bronchial reactiveness with histamine in patients with atopic dermatitis and bronchial asthma]. ( Faber, M; Jahnz-Rózyk, K; Paluchowska, E; Samochocki, Z, 1996) |
"With histamine in seven BDP-treated and in five placebo-treated patients, decrease in FEV1 > or = 20 percent from saline solution was paralleled by a significant decrease in tidal volume (VT), inspiratory time (Ti), and expiratory time (Te), and increase in respiratory frequency (RF)." | 6.67 | Preventive effects of beclomethasone on histamine-induced changes in breathing pattern in asthma. ( Duranti, R; Fanelli, A; Gorini, M; Maggi, E; Scano, G; Stendardi, L, 1993) |
" The provocative concentration causing a 20% fall in FEV1 (logPC20) was calculated by linear interpolation of log dose-response curves." | 6.67 | Effect of inhaled furosemide and bumetanide on adenosine 5'-monophosphate- and sodium metabisulfite-induced bronchoconstriction in asthmatic subjects. ( Barnes, PJ; Chen-Worsdell, YM; Chung, KF; Fuller, RW; O'Connor, BJ, 1991) |
" Airway response was measured as FEV1 and the dose of substance P (using a dose range of 23-736 nmol) producing a 20% decrease in FEV1 (PD20) was calculated from the individual semilogarithmic dose-response curves." | 6.66 | Effect of nedocromil on bronchospasm induced by inhalation of substance P in asthmatic subjects. ( Crimi, N; Mistretta, A; Oliveri, R; Palermo, B; Palermo, F; Polosa, R; Vancheri, C, 1988) |
"Terfenadine (Seldane) is a new, highly potent H1 histamine receptor antagonist that in clinically effective doses is free of side effects." | 6.66 | Terfenadine (Seldane) is a potent and selective histamine H1 receptor antagonist in asthmatic airways. ( Holgate, ST; Rafferty, P, 1987) |
"In 12 patients with bronchial asthma we performed histamine bronchial challenges before and four hours after ingestion of placebo, 2." | 6.66 | The inhibitory effect of azelastine and ketotifen on histamine-induced bronchoconstriction in asthmatic patients. ( Magnussen, H, 1987) |
"Azelastine did not inhibit the effect of inhaled LTC4; the geometric mean PD20FEV1 LTC4 (nmol) after a single dose and 14 days' treatment was 0." | 6.66 | Effect of azelastine on bronchoconstriction induced by histamine and leukotriene C4 in patients with extrinsic asthma. ( Albazzaz, MK; Patel, KR, 1988) |
"Pretreatment with albuterol abolished any significant bronchoconstriction, with mean maximal falls in SGaw and FEV1 after challenge of 7." | 6.66 | Influence of albuterol, cromolyn sodium and ipratropium bromide on the airway and circulating mediator responses to allergen bronchial provocation in asthma. ( Church, MK; Durham, SR; Holgate, ST; Howarth, PH; Kay, AB; Lee, TH, 1985) |
"Histamine PD20 FEV1 was assessed 4 h after the administration of salbutamol 200 micrograms, a combination of fenoterol 200 micrograms and ipratropium bromide 80 micrograms, and placebo." | 6.66 | Histamine-induced bronchial response after administration of placebo, salbutamol and a combination of a beta-2-adrenergic drug (fenoterol) with an anticholinergic agent (ipratropium bromide) in asymptomatic asthma patients. ( Cresci, F; Fontana, G; Mugnai, M; Panuccio, P, 1986) |
" Airway responsiveness thus appears to be a useful tool for evaluating inhaled beta 2-agonists and designing beta 2-agonist dosing regimens." | 6.66 | Use of bronchial provocation with histamine to compare the pharmacodynamics of inhaled albuterol and metaproterenol in patients with asthma. ( Ahrens, RC; Annis, L; Harris, JB; Milavetz, G; Ries, R, 1987) |
" The dose-response curves were compared by an analysis of variance." | 6.66 | Effects of clonidine on bronchial responses to histamine in normal and asthmatic subjects. ( Advenier, C; Dinh Xuan, AT; Lockhart, A; Mantrand, P; Matran, R; Regnard, J, 1988) |
"Verapamil was chosen because of its aqueous solubility and hence suitability for aerosol administration in higher doses than previously given." | 6.66 | Effects of the calcium channel blocker, verapamil, on asthmatic airway responses to muscarinic, histaminergic, and allergenic stimuli. ( Fish, JE; Norman, PS, 1986) |
"To determine whether treatment with atropine causes dose-dependent inhibition of histamine-induced bronchoconstriction, we constructed dose-response curves to inhaled histamine after inhalation of placebo and 0." | 6.65 | Variable inhibition of histamine-induced bronchoconstriction by atropine in subjects with asthma. ( Bethel, RA; Boushey, HA; Epstein, J; Nadel, JA; Sheppard, D; Skoogh, BE, 1984) |
"Nifedipine is a potent antagonist of calcium ion influx in smooth muscle and secretory cells, and these studies suggest that it may inhibit release of mast cell mediators and reduce bronchial smooth muscle contractility in asthma." | 6.65 | A calcium antagonist, nifedipine, modifies exercise-induced asthma. ( Barnes, PJ; Brown, MJ; Wilson, NM, 1981) |
"Twenty patients with extrinsic type bronchial asthma are shown to have a significant fall in vital capacity (V." | 6.63 | Effect of alpha-receptor blocking drugs and disodium cromoglyate on histamine hypersensitivity in bronchial asthma. ( Govindaraj, M; Kerr, JW; Patel, KR, 1970) |
"Histamine is a ubiquitous inflammatory mediator intimately associated with the pathology of allergy." | 6.46 | The role of histamine in asthma. ( Dunford, PJ; Holgate, ST, 2010) |
"Histamine is an important mast cell- and basophil-derived mediator that has been implicated in the pathogenesis of asthma, resulting in smooth muscle contraction, mucus hypersecretion, and increased vascular permeability leading to mucosal edema." | 6.41 | Second-generation antihistamines in asthma therapy: is there a protective effect? ( Walsh, GM, 2002) |
"Bronchial asthma is a chronic lung disorder, that affects an estimated 262 million people worldwide, thereby, causing a large socio-economic burden." | 5.72 | Orally administered solasodine, a steroidal glycoalkaloid, suppresses ovalbumin-induced exaggerated Th2-immune response in rat model of bronchial asthma. ( Arora, P; Chellappan, DK; Dua, K; Gupta, G; Nainwal, LM; Oliver, BG; Singh, SK, 2022) |
"Histamine intolerance is a clinically heterogeneous disease." | 5.36 | [Histamine intolerance mimics anorexia nervosa]. ( Herbst, RA; Peters, KP; Stolze, I, 2010) |
"We report a woman with bronchial asthma, who experienced two episodes of Matsutake-induced anaphylaxis." | 5.36 | A case of anaphylactic reaction following matsutake mushroom ingestion: demonstration of histamine release reaction of basophils. ( Nagase, H; Nakase, Y; Ohta, K; Sugimoto, N; Suzukawa, M; Toda, T; Yamaguchi, M, 2010) |
"Histamine has an important role in regulation of immune response which is mediated by differential expression of four distinct receptors, H1R-H4R." | 5.34 | Histamine 4 receptor activation induces recruitment of FoxP3+ T cells and inhibits allergic asthma in a murine model. ( Center, DM; Cross, L; Cruikshank, WW; Green, DS; Kornfeld, H; McAllister, B; Morgan, RK, 2007) |
"Adenosine plasma levels were significantly higher in sensitized than normal animals." | 5.34 | In vivo adenosine A(2B) receptor desensitization in guinea-pig airway smooth muscle: implications for asthma. ( Adinolfi, B; Blandizzi, C; Breschi, MC; Calderone, V; Camici, M; Fogli, S; Martinelli, C; Martinotti, E; Nieri, P, 2007) |
"Histamine plays an important role in the allergic inflammation." | 5.33 | No association of histamine- N-methyltransferase polymorphism with asthma or bronchial hyperresponsiveness in two German pediatric populations. ( Deichmann, K; Deindl, P; Heinzmann, A; Lau, S; Müller, S; Nickel, R; Niggemann, B; Peri-Jerkan, S; Sengler, C; Sommerfeld, C; Wahn, U, 2005) |
"Histamine is an important mediator in airway inflammation." | 5.33 | The role of antihistamines in asthma management. ( Wilson, AM, 2006) |
"Histamine production was about 1 mcg/mL at streptococci, staphylococci and hemophilic bacteria, from 1 to 3 mcg/mL - at bacilli, corynebacteria and Candida, from 1 to 10 mcg/mL - at lactobacilli, enterobacteria, pseudomonades, acinetobacteria." | 5.31 | [Resistance to antibiotics and histamine production at the bacteria, isolated from the stomatopharynx of the children with bronchial asthma]. ( Voropaeva, EA, 2002) |
"Histamine challenges were performed before and an average of 5 months after the consecutive treatment." | 5.29 | Bronchial hyperresponsiveness changes after 5 months of regular procaterol inhalation therapy in asthmatic children. ( Aoki, T; Iikura, Y; Kishida, M; Saito, S; Sasamoto, A, 1993) |
" Addition of antihistamines (mepyramine and metiamide) to the organ bath abolished the response to exogenous histamine, but failed to alter the dose-response relationship of the reaction to cumulative challenge with rising titres of anti-IgE." | 5.29 | Leukotrienes and histamine mediate IgE-dependent contractions of human bronchi: pharmacological evidence obtained with tissues from asthmatic and non-asthmatic subjects. ( Björck, T; Dahlén, SE, 1993) |
"Erythromycin is an antibiotic extensively used worldwide which is also reported to have anti-inflammatory action." | 5.28 | Erythromycin reduces the severity of bronchial hyperresponsiveness in asthma. ( Miyatake, H; Satake, T; Suzuki, R; Takagi, K; Taki, F; Taniguchi, H, 1991) |
"Histamine levels were increased fourfold in asthmatic subjects compared with those in normal subjects (p less than 0." | 5.28 | Evidence for elevated levels of histamine, prostaglandin D2, and other bronchoconstricting prostaglandins in the airways of subjects with mild asthma. ( Bleecker, ER; Hubbard, WC; Kagey-Sobotka, A; Lichtenstein, LM; Liu, MC; McLemore, TL; Niv, Y; Permutt, S; Proud, D, 1990) |
"The relationship of gastro oesophageal reflux (GER) with bronchial asthma has already been well documented in asthmatic subjects and it has been postulated that their asthma might have been caused by GER disease." | 5.28 | Histamine bronchoprovocation tests in subjects with gastro-oesophageal reflux disease. ( Agarwal, A; Bhandari, VM; Gupta, AN; Rishi, JP, 1990) |
" The threshold of sensitivity expressed as PD 20 VEMS and PD 40 sGAW are superimposable by the dosimetric technique but on the other hand, using the aerosol dosage method, the threshold of sensitivity expressed in PD 40 sGAW is significantly lower than that for PD 20 VEMS (p less than 0." | 5.28 | [Comparison of the effect of 2 methods of histamine administration on the bronchomotor response in asthmatics]. ( Duchateau, J; Michel, O; Sergysels, R, 1989) |
"Histamine levels were significantly higher in children with post-therapy improvement in PEFR of less than 20% (2,560 +/- 1,600) compared with those with greater than 20% (475 +/- 100), and in hospitalized (3,915 +/- 1,910) compared with nonhospitalized (408 +/- 130) children." | 5.27 | Plasma elevations of histamine and a prostaglandin metabolite in acute asthma. ( Asman, B; Fireman, P; Gillen, L; Page, R; Skoner, DP, 1988) |
"A histamine challenge was performed." | 5.27 | Influence of asthmatic and rhinitic symptomatology duration on bronchial responsiveness to histamine. ( Crimi, N; Distefano, SM; Mistretta, A; Oliveri, R; Palermo, B; Palermo, F; Polosa, R; Vancheri, C, 1987) |
" The slopes of log dose-response curves (SLDRC) to H and SLDRC to ACH were of similar magnitude both in N and AST and linearly related; however, for either agonist, bronchial sensitivity (PD40) and reactivity (SLDRC) failed to correlate." | 5.27 | The relationship between acetylcholine- and histamine-induced constriction of large airways in normal subjects and subjects with asthma: a possible role for postreceptor mechanisms. ( Popa, V, 1986) |
"Histamine challenges were performed on a heterogeneous group of adult asthmatic subjects." | 5.26 | Further studies on the mechanism of human histamine-induced asthma: the effect of an aerosolized H1 receptor antagonist (diphenhydramine). ( Casterline, CL; Evans, R, 1977) |
" The aerosol/infusion dosage ratio for comparable reductions of blood pressure were 1 for isoprenaline, and 10 for NP." | 5.26 | Comparison of sodium nitroprusside and isoprenaline aerosols in histamine-induced bronchial asthma of the guinea pig. ( Kreye, VA; Marquard, E, 1979) |
"Seven patients with bronchial asthma underwent bronchial inhalation challenge with aerosolized allergen extracts and methacholine." | 5.26 | Plasma histamine changes during provoked bronchospasm in asthmatic patients. ( Arroyave, CM; Bhat, KN; Marney, SR; Stevenson, DD; Tan, EM, 1976) |
"Histamine was released from the lung and was not attributable to the concomitant hypoxia." | 5.25 | Histamine release during antigen inhalation in experimental asthma in dogs. ( Chiesa, A; Dain, D; Gold, WM; Kessler, GF; Meyers, GL, 1975) |
"Low-dose salbutamol suppresses airway responsiveness to histamine but not methacholine in subjects with asthma." | 5.17 | Low-dose salbutamol suppresses airway responsiveness to histamine but not methacholine in subjects with asthma. ( Aizawa, H; Fukuyama, S; Inoue, H; Komori, M; Koto, H; Matsumoto, K; Takata, S; Yoshida, M, 2013) |
" Patients with mild-to-moderate persistent stable asthma taking 1,000 μg/day or less beclomethasone dipropionate equivalent received 10 or 20 mg of oral propranolol followed by histamine challenge, with recovery to nebulized salbutamol (5 mg)." | 5.16 | Sensitivity of impulse oscillometry and spirometry in beta-blocker induced bronchoconstriction and beta-agonist bronchodilatation in asthma. ( Lipworth, BJ; Short, PM; Williamson, PA, 2012) |
"Eighteen patients with mild allergic asthma who did not use any regular antiasthmatic therapy inhaled the long-acting beta(2)-agonist salmeterol for 2 weeks followed by 2 weeks of combination therapy with salmeterol and the corticosteroid fluticasone." | 5.14 | Adverse effects of salmeterol in asthma: a neuronal perspective. ( Bratke, K; Edner, A; Kuepper, M; Lindner, Y; Lommatzsch, M; Virchow, JC, 2009) |
" The objective was to evaluate the effects that treatment with intranasal beclomethasone dipropionate (BDP; 400 microg/d) has on nasal and bronchial symptoms, as well as on lung function test results and bronchial responsiveness to histamine in patients with allergic rhinitis and asthma." | 5.13 | Intranasal corticosteroid administration reduces nonspecific bronchial hyperresponsiveness and improves asthma symptoms. ( Agondi, RC; Giavina-Bianchi, P; Kalil, J; Machado, ML, 2008) |
"In this randomized controlled, double blind study, 30 asthmatics were challenged with histamine until forced expiratory volume in 1s (FEV(1)) fell with > or =20%." | 5.12 | Effects of long-acting bronchodilators and placebo on histamine-induced asthma symptoms and mild bronchusobstruction. ( De Peuter, S; Lemaigre, V; Smets, A; Van den Bergh, O; Verleden, GM, 2006) |
"Therefore, we compared the effects of beclomethasone dipropionate (BDP) on the degree of BHR to inhaled histamine and NKA in a double-blind, controlled, cross-over study of asthmatic patients." | 5.12 | Beclomethasone dipropionate attenuates airways hyperresponsiveness to neurokinin A and histamine in asthma. ( Arcidiacono, G; Ciamarra, I; Crimi, N; Polosa, R; Prosperini, G, 2006) |
"2 mg of salbutamol on histamine-induced bronchoconstriction was assessed in 101 steroid-naïve asthmatic subjects." | 5.12 | Determinants of the bronchodilation response to salbutamol on histamine-induced bronchoconstriction. ( Kiviniemi, V; Koskela, HO; Purokivi, MK; Taivainen, AH; Tukiainen, HO, 2006) |
"Previous studies do not provide a clear picture of the relationship between nitrogen dioxide (NO(2)) exposure and asthma." | 5.11 | Randomized controlled trial of unflued gas heater replacement on respiratory health of asthmatic schoolchildren. ( Hiller, JE; Martin, J; McElroy, HJ; Nitschke, M; Pilotto, LS; Pisaniello, D; Ruffin, RE; Smith, BJ, 2004) |
"Coughing during the isotonic histamine challenge was associated with the degree of the bronchoconstriction induced." | 5.11 | Interpretation of cough provoked by airway challenges. ( Kontra, KM; Koskela, HO; Purokivi, MK; Randell, JT, 2005) |
"To study the effect of montelukast (10 mg/day) on histamine and cysteinyl leukotriene release from basophils taken from 12 mild atopic asthmatic patients who took the drug for 4 weeks." | 5.11 | Effect of montelukast on basophil releasability in patients with asthma. ( Fireman, E; Kivity, S; Sade, K; Schwartz, Y, 2005) |
" We investigated the early effects of inhaled fluticasone propionate (FP) therapy on AR in 3 consecutive double-blind, randomized, placebo-controlled crossover studies in steroid-naive subjects with mild asthma." | 5.10 | Rapid effect of inhaled fluticasone propionate on airway responsiveness to adenosine 5'-monophosphate in mild asthma. ( Allenby, MI; Jensen, MW; Ketchell, RI; Lumley, P; O'connor, BJ; Wright, AM, 2002) |
"To compare a new bronchial provocation test, the mannitol challenge, with cold air and histamine challenges to demonstrate airway hyperresponsiveness (AHR) in patients with difficult-to-diagnose asthma." | 5.10 | Responsiveness to three bronchial provocation tests in patients with asthma. ( Anderson, SD; Brannan, JD; Chan, HK; Hyvärinen, L; Koskela, HO, 2003) |
"Nine subjects with atopic asthma received high-dose inhaled fluticasone propionate (FP), 2,000 microg/d for 8 weeks." | 5.10 | Alterations in airway inflammation and lung function during corticosteroid therapy for atopic asthma. ( Burke, CM; Demers, EA; Faul, JL; Poulter, LW, 2002) |
"In a randomised, double blind, placebo controlled, parallel study 25 patients with mild asthma (19-34 years, forced expiratory volume in one second (FEV1) >75% predicted, concentration of histamine provoking a fall in FEV1 of 20% or more (PC20) <4 mg/ml) inhaled fluticasone propionate (500 microg twice daily) for four weeks." | 5.09 | Effect of inhaled steroids on airway hyperresponsiveness, sputum eosinophils, and exhaled nitric oxide levels in patients with asthma. ( Bel, EH; Sterk, PJ; Straathof, KC; van Rensen, EL; Veselic-Charvat, MA; Zwinderman, AH, 1999) |
"The underlying mechanisms of bronchoconstriction in aspirin-intolerant asthmatics (AIAs) are still unknown, but the hypothesis of an altered metabolism of arachidonic acid is generally accepted." | 5.09 | Dynamics of eicosanoids in peripheral blood cells during bronchial provocation in aspirin-intolerant asthmatics. ( Baenkler, HW; Göde, UC; Schäfer, D; Schmid, M, 1999) |
" Samples from healthy and atopic asthmatic subjects were treated with either DTE or phosphate-buffered saline (PBS) at 22 or 37 degrees C and compared for cell counts and concentrations of histamine, tryptase, eosinophil cationic protein (ECP), free interleukin (IL)-8, immunoglobulin (Ig)A, IL-8/IgA complexes and secretory component (SC)." | 5.09 | The effect of processing on inflammatory markers in induced sputum. ( Djukanovic, R; Goldring, K; Lau, LC; Louis, R; Perks, B; Radermecker, M; Shute, J, 1999) |
" The nebulized provocative concentration of histamine causing a 20% fall in forced expiratory volume in one second in asthmatics was found to be approximately half that of a standard method when compared with the reservoir system (mean ratio 2." | 5.09 | Aerosol recovery from large-volume reservoir delivery systems is highly dependent on the static properties of the reservoir. ( van der Veen, MJ; van der Zee, JS, 1999) |
"A study was undertaken to determine whether swimming training improved aerobic capacity, exercise induced bronchoconstriction (EIB), and bronchial responsiveness to inhaled histamine in children with asthma." | 5.09 | Effects of swimming training on aerobic capacity and exercise induced bronchoconstriction in children with bronchial asthma. ( Araki, H; Higaki, Y; Matsumoto, I; Nishima, S; Odajima, H; Shindo, M; Tanaka, H; Tanaka, M; Tsuda, K, 1999) |
" We undertook a double-blind, randomized, placebo-controlled, cross-over study to investigate the effects of a single dose of formoterol inhaled via Turbuhaler (12 micrograms) and of albuterol inhaled via Turbuhaler (200 micrograms) on airway responsiveness to AMP and histamine in 16 subjects with mild atopic asthma." | 5.09 | Differential effect of formoterol on adenosine monophosphate and histamine reactivity in asthma. ( Barnes, PJ; Nightingale, JA; Rogers, DF, 1999) |
"We sought to test the efficacy of oral antifungal treatment for Trichophyton-induced asthma by using fluconazole in a placebo-controlled trial." | 5.09 | Treatment of late-onset asthma with fluconazole. ( Hayden, ML; Jackson, S; Platts-Mills, TA; Ward, GW; Woodfolk, JA, 1999) |
"In a double blind, crossover study 14 asthmatic patients received pretreatment with oral L-arginine (50 mg/kg body weight) or placebo prior to histamine challenge." | 5.09 | Effect of oral L-arginine on airway hyperresponsiveness to histamine in asthma. ( de Gouw, HW; Sterk, PJ; Twiss, IM; Verbruggen, MB, 1999) |
"The purpose of our study was to evaluate the response of persons with mild asthma to inhaled allergen after ozone exposure conditions similar to those observed in urban areas of the United States." | 5.09 | Increased specific airway reactivity of persons with mild allergic asthma after 7.6 hours of exposure to 0.16 ppm ozone. ( Ball, B; Folinsbee, LJ; Horstman, D; Kehrl, HR; Peden, DB, 1999) |
" placebo in 15 mild asthmatic patients, selected by their response to a histamine challenge (decrease in FEV1 > 20% to less than 18 mg mL-1 of histamine [PC20])." | 5.09 | Lidocaine inhalation for local anaesthesia and attenuation of bronchial hyper-reactivity with least airway irritation. Effect of three different dose regimens. ( Beste, M; Groeben, H; Grosswendt, T; Peters, J; Silvanus, M, 2000) |
"We investigated in a clinical setting whether increased intake of linoleic acid alters respiratory function in 26 mild asthmatics." | 5.09 | The role of n-6 polyunsaturated fat in stable asthmatics. ( Clifton, PM; Morris, A; Noakes, M, 2001) |
"We previously reported that inhaled acetaldehyde, a metabolite of ethanol and a main factor in alcohol-induced asthma, causes bronchoconstriction indirectly through endogenously released histamine in asthmatic subjects." | 5.08 | Repeated inhalation challenge with exogenous and endogenous histamine released by acetaldehyde inhalation in asthmatic patients. ( Bando, T; Fujimura, M; Kamio, Y; Matsuda, T; Myou, S; Nakatsumi, Y, 1995) |
"We examined the effect of procaterol, a beta 2-adrenoceptor agonist, on skin whealing responses to histamine, platelet-activating factor (PAF), substance P, or bradykinin in eight asthmatic children in a double-blind, randomized, cross-over study." | 5.08 | Effect of procaterol, a beta 2-adrenoceptor agonist, on skin whealing response caused by inflammatory mediators in asthmatic children. ( Arakawa, H; Maeda, S; Morikawa, A; Tokuyama, K, 1995) |
"Eleven atopic asthmatic subjects underwent two concentration-response studies, separated by 1 hour, with either inhaled histamine or bradykinin." | 5.08 | Cross refractoriness between bradykinin and hypertonic saline challenges in asthma. ( Holgate, ST; Howarth, PH; Makker, HK; Rajakulasingam, K, 1995) |
"Bradykinin is a potent vasoactive peptide which has been proposed as an important inflammatory mediator in asthma since it provokes potent bronchoconstriction in asthmatic subjects." | 5.08 | Effect of an inhaled neutral endopeptidase inhibitor, phosphoramidon, on baseline airway calibre and bronchial responsiveness to bradykinin in asthma. ( Crimi, N; Magrì, S; Mastruzzo, C; Mistretta, A; Polosa, R; Prosperini, G; Pulvirenti, G; Santonocito, G, 1995) |
"We evaluated the effect of inhaled indomethacin, a nonsteroidal antiinflammatory drug (NSAID), against bronchoconstriction induced by ultrasonically nebulized distilled water (UNDW) in children with asthma." | 5.08 | Inhaled indomethacin prevents bronchoconstrictive response to distilled water but not to histamine in children with asthma. ( Kuroume, T; Maeda, S; Mochizuki, H; Morikawa, A; Shigeta, M; Shimizu, T, 1995) |
"In study 1 the UNDW, AA, and histamine inhalation challenges were performed in 40 asthmatic children (26 boys, aged from 7 to 16 years; mean +/- SD, 11." | 5.08 | Relationship between ultrasonically nebulized distilled water-induced bronchoconstriction and acetic acid-induced cough in asthmatic children. ( Kuroume, T; Maeda, S; Mochizuki, H; Morikawa, A; Shimizu, T; Tokuyama, K, 1995) |
"On 2 consecutive days, we performed a CACh and a histamine challenge in 128 symptom- and medication-free pediatric and adolescent asthma patients." | 5.08 | A comparison of a single-step cold-dry air challenge and a routine histamine provocation for the assessment of bronchial responsiveness in children and adolescents. ( Eber, E; Modl, M; Steinbrugger, B; Weinhandl, E; Zach, MS, 1995) |
" To test this hypothesis, we have examined the effect of thiorphan, an NEP inhibitor, on the protection afforded by inhaled ANP against histamine-induced bronchoconstriction in 10 mildly asthmatic patients." | 5.08 | Effect of inhaled atrial natriuretic peptide and a neutral endopeptidase inhibitor on histamine-induced bronchoconstriction. ( Angus, RM; Chalmers, GW; Millar, EA; Thomson, NC, 1995) |
"Several studies have suggested that patients with bronchial asthma are more susceptible to the potential effects of nitrogen dioxide (NO2) than healthy subjects, with respect to airway responsiveness and lung function." | 5.08 | The effect of 1 ppm nitrogen dioxide on bronchoalveolar lavage cells and inflammatory mediators in normal and asthmatic subjects. ( Grimminger, F; Jörres, R; Magnussen, H; Nowak, D; Oldigs, M; Seeger, W, 1995) |
"Eight atopic men with mild to moderate asthma aged 19 to 31 years, (forced expiratory volume in 1 second [FEV1] > or = 67% of predicted value, histamine provocative concentration causing a 20% fall in FEV1 [PC20] < 4 mg/ml) and documented EAR and LAR to house dust mite extract participated in a two-period, double-blind, placebo-controlled, crossover study." | 5.08 | The effect of MK-0591, a novel 5-lipoxygenase activating protein inhibitor, on leukotriene biosynthesis and allergen-induced airway responses in asthmatic subjects in vivo. ( Bel, EH; De Smet, M; Depré, M; Diamant, Z; Friedman, BS; Hilliard, D; Sterk, PJ; Timmers, MC; van der Veen, H, 1995) |
" Responses to inhaled allergen were measured in 16 subjects with allergic asthma (age range, 18 to 35 years) after 7 days of treatment with either placebo, once daily slow-release theophylline producing a mean +/- SD serum concentration of 16 +/- 5 micrograms/ml during the late phase, or 2 mg of cromolyn administered by MDI four times daily." | 5.08 | Theophylline attenuation of airway responses to allergen: comparison with cromolyn metered-dose inhaler. ( Blake, K; Delafuente, J; Harman, E; Hendeles, L; Huang, D; O'Brien, R, 1995) |
" A single and a multiple step cold air challenge and a histamine provocation were performed in random order on three consecutive days on 28 children and adolescents with bronchial asthma, who were currently symptom- and medication-free." | 5.08 | Comparing methods for assessing bronchial responsiveness in children: single step cold air challenge, multiple step cold air challenge, and histamine provocation. ( Eber, E; Modl, M; Steinbrugger, B; Weinhandl, E; Zach, MS, 1995) |
"To test the hypothesis that surfactant nebulization improves pulmonary function and reduces bronchial responsiveness to histamine, we studied 12 children with asthma." | 5.08 | Surfactant nebulization does not alter airflow obstruction and bronchial responsiveness to histamine in asthmatic children. ( Bos, H; Dorrepaal, C; Gerritsen, J; Koëter, GH; Oetomo, SB; van Aalderen, WM; van der Mark, TW, 1996) |
" Morning baseline values of urinary 9 alpha, 11 beta-PGF2 were measured in three groups--healthy volunteers (n = 9), patients with atopic asthma (n = 14), and aspirin-intolerant patients with asthma (n = 12)--and found to be very similar, 54 +/- 9, 62 +/- 6, and 71 +/- 15 ng/mmol creatinine, respectively (means +/- SEM)." | 5.08 | Increased urinary excretion of the prostaglandin D2 metabolite 9 alpha, 11 beta-prostaglandin F2 after aspirin challenge supports mast cell activation in aspirin-induced airway obstruction. ( Dahlén, B; Dahlén, SE; Kumlin, M; O'Sullivan, S, 1996) |
"When administered by inhalation, histamine provokes dose-related bronchoconstriction in asthmatic subjects mainly by a direct activation of histamine H1-receptors on airway smooth muscle." | 5.08 | Inhaled lysine acetylsalicylate (L-ASA) attenuates histamine-induced bronchoconstriction in asthma. ( Crimi, N; Magrì, S; Mastruzzo, C; Mistretta, A; Paolino, G; Polosa, R; Prosperini, G, 1996) |
"Clinical and epidemiologic studies suggest that ambient ozone exposure may increase the response of patients with asthma to inhaled allergen." | 5.08 | Allergen bronchoprovocation of patients with mild allergic asthma after ozone exposure. ( Ball, BA; Folinsbee, LJ; Kehrl, HR; Peden, DB, 1996) |
"To elucidate differences in lung mechanics, we investigated the relative changes of partial forced expiratory flows at 50 and 30% of vital capacity, pulmonary resistance (RL), dynamic elastance (Edyn), and the effects of a deep inhalation (DI) on maximal flows, Edyn, and RL in eight asthmatic and eight normal individuals during bronchial challenges with methacholine, histamine, and ATP." | 5.08 | Lung mechanics during induced bronchoconstriction. ( Jenouri, G; Pellegrino, R; Rodarte, JR; Wilson, O, 1996) |
"In a randomized, double-blind, placebo controlled cross-over study we have investigated the effect of intravenous magnesium on airway calibre and airway reactivity to histamine in 20 subjects with mild to moderate asthma." | 5.08 | Effect of intravenous magnesium sulphate on airway calibre and airway reactivity to histamine in asthmatic subjects. ( Britton, J; Hill, JM, 1996) |
"Sixteen subjects with mild stable asthma inhaled budesonide 800 micrograms twice daily for two periods of 14 days with terbutaline 1000 micrograms three times daily or placebo in a double blind crossover fashion." | 5.08 | Effect of regular terbutaline on the airway response to inhaled budesonide. ( Bennett, JA; Clark, MM; Oborne, J; Tattersfield, AE; Wilding, PJ, 1996) |
"To explore this further, the airway responsiveness to sodium metabisulphite (MBS), an indirect neural stimulus with similar characteristics to bradykinin, was compared in 18 mild steroid-naive asthmatic subjects with the airway responsiveness to histamine before and after allergen challenge with extracts of house dust mite, grass pollen, or cat." | 5.08 | Effect of allergen challenge on airway responsiveness to histamine and sodium metabisulphite in mild asthma. ( Coulby, LJ; Evans, DJ; O'Connor, BJ, 1996) |
" A study was performed to evaluate whether there are differences in the perception of histamine induced bronchoconstriction between anxious and non-anxious perceivers and whether anxious perception of bronchoconstriction can be predicted by higher levels of baseline anxiety." | 5.08 | Association of anxiety with perception of histamine induced bronchoconstriction in patients with asthma. ( Spinhoven, P; Sterk, PJ; Van der Does, AJ; van Peski-Oosterbaan, AS; Willems, LN, 1997) |
"The response to histamine and AMP challenges and the protection afforded by terbutaline (500 micrograms) against these two challenges was measured on two occasions two weeks apart in 20 subjects with asthma (19 completed the study)." | 5.08 | Adenosine monophosphate and histamine induced bronchoconstriction: repeatability and protection by terbutaline. ( Egbagbe, E; Pavord, ID; Tattersfield, AE; Thompson-Coon, J; Wilding, P, 1997) |
"We conclude that the severity of cold, as induced by experimental RV16 infection, is a determinant of the increase in airway hypersensitivity to histamine in patients with asthma." | 5.08 | Effect of experimental rhinovirus 16 colds on airway hyperresponsiveness to histamine and interleukin-8 in nasal lavage in asthmatic subjects in vivo. ( de Klerk, EP; Dick, EC; Grünberg, K; Hiemstra, PS; Smits, HH; Spaan, WJ; Sterk, PJ; Timmers, MC, 1997) |
"To measure the effects of a single inhaled nebulized dose of 180 mg magnesium sulphate on airway reactivity to a direct-acting bronchoconstrictor (histamine) and an indirect-acting bronchoconstrictor (adenosine monophosphate [AMP]) in asthmatic subjects." | 5.08 | Studies of the effects of inhaled magnesium on airway reactivity to histamine and adenosine monophosphate in asthmatic subjects. ( Britton, J; Hill, J; Lewis, S, 1997) |
" Mast cells play very important role in early phase of asthmatic reaction, releasing many proinflammatory mediators including histamine." | 5.08 | [The influence of heparin on histamine level in plasma during the early reaction phase of asthma]. ( Antczak-Marczak, M; Kuna, P, 1997) |
" One hundred and fourteen of the 131 patients diagnosed as having asthma when the histamine challenge test was used were not diagnosed by PEF variability." | 5.08 | Testing bronchial hyper-responsiveness: provocation or peak expiratory flow variability? ( den Otter, JJ; Molema, J; Reijnen, GM; van den Bosch, WJ; van Schayck, CP; van Weel, C, 1997) |
" In Experiment 1, asthmatic wheezing sounds were recorded in 16 children during histamine-induced airway obstruction." | 5.08 | The influence of respiratory sounds on breathlessness in children with asthma: a symptom-perception approach. ( Colland, VT; Kolk, AM; Prins, PJ; Rietveld, S, 1997) |
"In a group of 55 children in the age of 7-14 years with mild or severe asthma, the evaluation of inhaled budesonide (in pulmicort and horacort) effect on bronchial reactivity and adrenal cortex function was made." | 5.08 | [Comparison of the effect of two budesonide preparations for treatment of bronchial asthma in children]. ( Dolatkowski, R; Gaszczyk, G; Latoś, T, 1997) |
" We undertook two double-blind, randomized, crossover, placebo-controlled studies to investigate the effects of salmeterol and albuterol on airway responsiveness (AR) to AMP and histamine in patients with mild asthma." | 5.08 | Comparison of salmeterol and albuterol-induced bronchoprotection against adenosine monophosphate and histamine in mild asthma. ( Aikman, SL; Barnes, PJ; Harris, JG; Jensen, MW; O'Connor, BJ; Taylor, DA, 1997) |
"The aim of this study was to examine the inter-relationships between the different effects of deep breaths and histamine provocation on airway function in patients with bronchial asthma." | 5.08 | Excessive bronchoconstriction induced by histamine and effects of volume history in patients with bronchial asthma. ( Ang, SM; Lim, TK, 1997) |
"The efficacy of nedocromil sodium (NED) (8mg twice daily) in controlling the clinical symptoms of asthma (score symptoms), the pulmonary parameters (FEV1, FVC) and bronchial hyperreactivity to histamine was assessed." | 5.08 | [The effect of nedocromil sodium on the clinical course, ventilatory parameters and nonspecific bronchial hyperreactivity in patients with nonatopic bronchial asthma treated with beclomethasone dipropionate]. ( Grabski, W; Grzelewska-Rzymowska, I; Kroczyńska-Bednarek, J; Tymińska, K, 1997) |
"The aim of the study was to determine whether zileuton, an inhibitor of 5-lipoxygenase, attenuated bronchial hyperresponsiveness (BHR) in asthmatic subjects who had marked BHR during maintenance treatment with inhaled corticosteroids (ICS)." | 5.08 | Effects of single-dose zileuton on bronchial hyperresponsiveness in asthmatic patients treated with inhaled corticosteroids. ( Bootsma, GP; Dekhuijzen, PN; Festen, J; van den Berg, LR; van Herwaarden, CL; Wielders, PL, 1997) |
"Breathing pattern variability was determined in 10 asthmatic adolescents during repeated bronchial histamine and methacholine challenges (HiCh/MeCh)." | 5.08 | Breathing pattern variability during bronchial histamine and methacholine challenges in asthmatics. ( Gustafsson, PM; Strömberg, NO, 1996) |
"From bronchoprovocation studies and investigations of the acute effects of drugs that inhibit leukotrienes (LT), the hypothesis has emerged that leukotrienes are important mediators of airway obstruction and other symptoms in aspirin-intolerant asthma (AIA)." | 5.08 | Benefits from adding the 5-lipoxygenase inhibitor zileuton to conventional therapy in aspirin-intolerant asthmatics. ( Bochenek, G; Boodhoo, TI; Dahlén, B; Dahlén, SE; Dubé, LM; Kumlin, M; Mastalerz, L; Nizankowska, E; Pinis, G; Swanson, LJ; Szczeklik, A; Wright, S; Zetterström, O, 1998) |
"We investigated whether the deterioration in asthma control reported following cessation of theophylline was due to tolerance to theophylline." | 5.08 | The airway effects of stopping regular oral theophylline in patients with asthma. ( Bennett, JA; Pavord, ID; Tattersfield, AE; Thompson Coon, J; Wilding, PJ, 1998) |
"We evaluated the effects of a new semisynthetic macrolide antibiotic, roxithromycin, on the bronchial hyperresponsiveness to histamine in children with asthma." | 5.07 | Roxithromycin reduces the degree of bronchial hyperresponsiveness in children with asthma. ( Kato, M; Kuroume, T; Mochizuki, H; Morikawa, A; Shimizu, T; Tokuyama, K, 1994) |
"The increase in nasal symptoms in aspirin-sensitive patients with asthma after aspirin ingestion is associated with increases in nasal tryptase, histamine, and cysteinyl leukotriene levels." | 5.07 | Direct evidence for a role of the mast cell in the nasal response to aspirin in aspirin-sensitive asthma. ( Callery, JC; Cohn, J; Drazen, JM; Fischer, AR; Igarashi, Y; Kaliner, MA; Lilly, CM; Rosenberg, MA; Rubin, P; White, MV, 1994) |
" Their airway smooth muscle relaxant potencies and effect on histamine contraction in human bronchi in vitro were compared with their effects on airway calibre and histamine reactivity in asthmatic subjects in vivo." | 5.07 | Comparison of the effects of salbutamol and adrenaline on airway smooth muscle contractility in vitro and on bronchial reactivity in vivo. ( Baldwin, DR; Knox, AJ; Pavord, ID; Sivardeen, Z, 1994) |
"In atopic asthmatics we have found, that 2 weeks of regular inhalative salbutamol monotherapy (200 mcg/qid) enhances BHR to histamine." | 5.07 | [Inhalation corticosteroid therapy and nonspecific bronchial responsiveness enhanced with salbutamol]. ( Brzostek, D; Droszcz, W; Piotrowska, B, 1994) |
"Using histamine inhalation tests, we followed changes in bronchial hypersensitivity in 48 children with atopic dermatitis (AD) who were nonasthmatic on their initial visit." | 5.07 | [Bronchial hypersensitivity and development of bronchial asthma in children with atopic dermatitis]. ( Adachi, Y; Ikarashi, T; Iwaya, M; Kayahara, M; Matsuno, M; Murakami, G; Onoue, Y; Takayanagi, M, 1994) |
"In order to examine the changes in bronchial hypersensitivity, histamine inhalation tests were evaluated in 27 asthmatic children who remitted." | 5.07 | [Bronchial hypersensitivity to histamine in asthmatic children longitudinal study from first visit to remitted state]. ( Adachi, Y; Ikarashi, T; Iwaya, M; Kayahara, M; Matsuno, M; Murakami, G; Onoue, Y; Takayanagi, M, 1994) |
"We performed a study of the action of chlorpheniramine, terfenadine, brompheniramine, cetirizine, cyproheptadine, clemastine, and astemizole compared with placebo on histamine-induced skin wheals and bronchoconstriction in a single group of patients with asthma." | 5.07 | The comparative actions and adverse effect profile of single doses of H1-receptor antihistamines in the airways and skin of subjects with asthma. ( Holgate, ST; Wood-Baker, R, 1993) |
"Azelastine significantly inhibited the development of the early asthmatic response." | 5.07 | The effect of H1-receptor blockade on the development of early- and late-phase bronchoconstriction and increased bronchial responsiveness in allergen-induced asthma. ( Holgate, ST; Ollier, S; Twentyman, OP, 1993) |
"Neurokinin A (NKA) elicits a potent contractile effect in asthmatic airways." | 5.07 | Effect of oral terfenadine on bronchoconstrictor response to inhaled neurokinin A and histamine in asthmatic subjects. ( Crimi, N; Mistretta, A; Oliveri, R; Palemo, F; Polosa, R; Prosperini, G; Pulvirenti, G, 1993) |
"To assess the effect of a single oral dose of caffeine (5 mg/kg) on FEV1 and bronchial responsiveness to histamine a double blind, placebo controlled study was performed in eight patients with mild stable asthma." | 5.07 | Decrease of histamine induced bronchoconstriction by caffeine in mild asthma. ( Fuller, RW; Henderson, JC; O'Connell, F, 1993) |
" In a double blind, randomised, crossover study the effect of preservatives in determining the airway responses to 5 mg of terbutaline was studied in a group of 21 atopic asthmatic patients." | 5.07 | Effect of preservative on the efficacy of terbutaline nebuliser solution in atopic asthma. ( Chan, CH; Lai, CK, 1993) |
"The effect of inhaled levomepromazine (Nozinan, Veractil) on bronchial responsiveness to inhaled histamine was investigated in asthmatics." | 5.07 | The protective effect of inhaled levomepromazine (Nozinan) on histamine-induced bronchial constriction. ( Banning, AM; Engel, AM; Faurschou, P; Madsen, F; Rosetzsky, A; Sjøgren, P, 1993) |
"To elucidate the role of leukotrienes (LT) in allergic asthma in humans the effect of MK-886, an LT biosynthesis inhibitor, was evaluated on antigen-induced early (EAR) and late (LAR) asthmatic reactions and bronchial responsiveness to histamine." | 5.07 | Oral leukotriene inhibitor (MK-886) blocks allergen-induced airway responses. ( Bel, EH; Buntinx, A; Friedman, BS; Han, YH; Shingo, S; Spector, R; Sterk, P; Tanaka, W, 1993) |
" A group of 10 mild atopic asthmatic subjects (6 males; FEV1 > 60% of predicted; PC20 histamine < or = 8 mg/ml; and on inhaled beta 2-agonists only) were studied before and after a 2-wk period of FP (1,000 micrograms/day) or placebo administered by metered-dose inhalers as two puffs twice per day through a large-volume spacer." | 5.07 | Differential effects of fluticasone propionate on allergen-evoked bronchoconstriction and increased urinary leukotriene E4 excretion. ( Fuller, RW; Gillies, B; O'Shaughnessy, KM; Wellings, R, 1993) |
"A double-blind, randomized, placebo-controlled, parallel-group study was undertaken in 120 clinically stable asthmatic children (aged 6-19 years) to determine the ability of 8 weeks of treatment with nedocromil sodium (4 mg, three times a day) to reduce the level of histamine responsiveness." | 5.07 | The effect of nedocromil sodium on histamine responsiveness in clinically stable asthmatic children. ( Burton, PR; Foo, AL; Lanteri, CJ; Sly, PD, 1993) |
"Twenty-four adult asthmatic subjects were included in a parallel group study that compared the duration of effect of two antihistamines and a placebo on cutaneous and inhaled reactivity to histamine." | 5.07 | Duration of effect of loratadine and terfenadine administered once a day for one week on cutaneous and inhaled reactivity to histamine. ( Cartier, A; Ghezzo, H; L'Archevêque, J; Labrecque, M; Malo, JL; Trudeau, C, 1993) |
"5 mg, on airway function and airway responsiveness to histamine and methacholine has been investigated in asthmatic patients." | 5.07 | Effect of an oral potassium channel activator, BRL 38227, on airway function and responsiveness in asthmatic patients: comparison with oral salbutamol. ( Barnes, PJ; Chung, KF; Fuller, RW; Kidney, JC; Lavender, EA; Worsdell, YM, 1993) |
"The effect of indomethacin on the capacity of LTE4 to enhance airway histamine responsiveness was evaluated in eight mild asthmatic subjects." | 5.07 | Effect of indomethacin on leukotriene4-induced histamine hyperresponsiveness in asthmatic subjects. ( Christie, PE; Hawksworth, R; Lee, TH; Spur, BW, 1992) |
" In a placebo-controlled, double-blind randomized study in asthmatic and hypertensive patients lung function and bronchial reactivity to histamine and bradykinin remained unaltered although in hypertensive patients with cough, reactivity to histamine tended to be more pronounced and bronchial hyperreactivity to be more frequent than in those without cough." | 5.07 | Cough induced by ACE-inhibitors. A kinin related phenomenon? ( Müller, B; Müller, M; Overlack, A; Scheid, ML; Schmidt, L; Stumpe, KO, 1992) |
" In a placebo-controlled, double-blind randomised study, the effect of captopril on lung function and bronchial reactivity to histamine and bradykinin was investigated in eight asthmatic and 12 hypertensive patients (six with and six without cough during previous ACE inhibition)." | 5.07 | Airway responsiveness and cough induced by angiotensin converting enzyme inhibition. ( Müller, B; Müller, M; Overlack, A; Scheid, ML; Schmidt, L; Stumpe, KO, 1992) |
"We studied the comparative modification of histamine- and methacholine-induced bronchoconstriction by a calcium antagonist, gallopamil, in 8 subjects with bronchial asthma." | 5.07 | Modification of histamine- and methacholine-induced bronchoconstriction by calcium antagonist gallopamil in asthmatics. ( Ahmed, T; Danta, I, 1992) |
"Sixteen subjects with mild stable asthma participated in a randomized double blind study on the effects of low dose fenoterol against histamine induced bronchoconstriction." | 5.07 | Low dose fenoterol aerosol protects against histamine-induced bronchoconstriction in mild asthmatics: a dose response study. ( Magnussen, H; Rabe, KF, 1992) |
"To examine whether leukotrienes, histamine, and methacholine have different sites of bronchoconstrictor action, we studied 8 stable asthmatic subjects (mean age +/- SD, 26 +/- 5 yr) on 3 different days." | 5.07 | Changes in cross-sectional airway areas induced by methacholine, histamine, and LTC4 in asthmatic subjects. ( Drazen, JM; Hoffstein, V; McClean, PA; Molfino, NA; Rebuck, AS; Slutsky, AS; Zamel, N, 1992) |
"The effect of gallopamil on the late-phase response to inhaled allergen was evaluated in six young adults with allergic asthma in a crossover manner." | 5.07 | The effect of inhaled gallopamil, a potent calcium channel blocker, on the late-phase response in subjects with allergic asthma. ( Harman, E; Hendeles, L; Hoppe, M, 1992) |
"Allergen-induced increase in airway responsiveness to histamine or methacholine provides a useful model for investigation of prophylactic or "antiinflammatory" asthma treatments." | 5.07 | Allergen-induced increase in airway responsiveness is not inhibited by acute treatment with ketotifen or clemastine. ( Cockcroft, DW; Gore, BC; Keshmiri, M; Murdock, KY, 1992) |
"The effect of hyposensitization (HS) upon the allergen evoked immediate asthmatic reaction (IAR), late asthmatic reaction (LAR) and upon bronchial reactivity towards histamine was examined." | 5.07 | Effect of hyposensitization upon the immediate and late asthmatic reaction and upon histamine reactivity in patients allergic to house dust mite (Dermatophagoides pteronyssinus). ( Stevens, WJ; Van Bever, HP, 1992) |
" We investigated the contribution of the mast cell products, histamine and prostaglandins, to the bronchoconstriction induced by isocapnic hyperventilation (ISH) using single doses of terfenadine, a specific histamine H1-receptor antagonist, and flurbiprofen, a potent cyclooxygenase inhibitor." | 5.07 | The relative contributions of histamine and prostanoids to bronchoconstriction provoked by isocapnic hyperventilation in asthma. ( Finnerty, JP; Harvey, A; Holgate, ST, 1992) |
"Astemizole, administered for seven days to asthmatic subjects, had an effect of bronchoconstriction induced by inhaled histamine for a mean period of 42 days." | 5.07 | Single-dose effect of astemizole on bronchoconstriction induced by histamine in asthmatic subjects. ( Benoît, C; Cartier, A; Ghezzo, H; Malo, JL, 1992) |
"Ibudilast, a unique agent with vasodilating and antiallergic actions, was studied in 13 asthmatics for its effect on airway hypersensitivity to histamine inhalation." | 5.07 | Effect of ibudilast: a novel antiasthmatic agent, on airway hypersensitivity in bronchial asthma. ( Hoshino, K; Kawasaki, A; Mizushima, Y; Osaki, R; Yano, S, 1992) |
"A long-term study of the effect of cromolyn sodium against bronchial hyperresponsiveness in asthmatic children is described." | 5.07 | The effect of disodium cromoglycate against bronchial hyperresponsiveness in asthmatic children. ( Watanabe, H, 1992) |
"The effects of prior inhalation of each of the sulfidopeptide leukotrienes (LT), LTC4, LTD4, and LTE4 on airway responsiveness to histamine have been compared in seven asthmatic and six normal subjects." | 5.07 | Leukotrienes C4, D4, and E4 enhance histamine responsiveness in asthmatic airways. ( Arm, JP; Fong, CY; Hawksworth, RJ; Lee, TH; O'Hickey, SP; Spur, BW, 1991) |
" The effect of both a single dose (15 mg) and 7 days of treatment (15 mg twice daily) with cetirizine, a potent H1 antagonist on bronchoconstriction induced by histamine and leukotriene D4 (LTD4) has been examined in 10 patients with mild atopic asthma in a placebo-controlled, double-blind, crossover study." | 5.07 | Effect of cetirizine on histamine- and leukotriene D4-induced bronchoconstriction in patients with atopic asthma. ( De Vos, C; Ghosh, SK; McIlroy, I; Patel, KR, 1991) |
"Asthmatic subjects were challenged with aerosols of hyper- and hypotonic saline 15 min (Group A) and 90 min (Group B) after inhaling clemastine." | 5.07 | Inhaled clemastine, an H1 antihistamine inhibits airway narrowing caused by aerosols of non-isotonic saline. ( Anderson, SD; Rodwell, LT; Seale, JP, 1991) |
"The effect of felodipine, a new selective calcium antagonist, was assessed on histamine and adenosine monophosphate (AMP) induced bronchoconstriction in 9 mild atopic asthmatics." | 5.07 | Effect of felodipine on histamine and adenosine induced bronchoconstriction in patients with asthma. ( Ghosh, SK; Rafferty, P, 1991) |
"Recent studies have demonstrated that elevation of plasma atrial natriuretic factor (ANF) levels may produce significant bronchodilation in the constricted asthmatic airway." | 5.07 | Influence of elevated plasma levels of atrial natriuretic factor on bronchial reactivity in asthma. ( Connell, JM; Hulks, G; Jardine, AG; Thomson, NC, 1991) |
" Following treatment with budesonide or placebo for three weeks in a double-blind, crossover trial with a three-week washout, the response to histamine and bradykinin was determined in ten patients with mild asthma." | 5.07 | Action of budesonide on asthmatic bronchial hyperresponsiveness. Effects on directly and indirectly acting bronchoconstrictors. ( Choudry, NB; Eriksson, G; Fuller, RW, 1991) |
"Antiinflammatory therapy with inhaled budesonide is an effective first-line treatment for patients with newly detected, mild asthma, and it is superior to the use of terbutaline in such patients." | 5.07 | Comparison of a beta 2-agonist, terbutaline, with an inhaled corticosteroid, budesonide, in newly detected asthma. ( Haahtela, T; Järvinen, M; Kava, T; Kiviranta, K; Koskinen, S; Lehtonen, K; Nikander, K; Persson, T; Reinikainen, K; Selroos, O, 1991) |
" The effects of a new long-acting inhaled beta 2-adrenoceptor agonist aerosol formoterol (12 micrograms), on FEV1, and on methacholine-induced bronchoconstriction, were compared with those of terbutaline (250 micrograms) and placebo in 12 midly asthmatic subjects." | 5.06 | Effect of formoterol, a long-lasting beta 2-adrenoceptor agonist, against methacholine-induced bronchoconstriction. ( Barnes, PJ; Chung, KF; Nichol, GM; Nix, A; Robson, A, 1990) |
"Bradykinin, a nonapeptide cleavage product of high molecular weight kininogen, is a potent bronchoconstrictor agonist in asthma; however, its mechanism of action is not known." | 5.06 | Contribution of histamine and prostanoids to bronchoconstriction provoked by inhaled bradykinin in atopic asthma. ( Holgate, ST; Lai, CK; Phillips, GD; Polosa, R, 1990) |
"We compared the effects of pretreatment of 800 micrograms of inhaled Smith Kline & French (SK&F) 104353, a leukotriene receptor antagonist, and 120 mg of oral terfenadine on the bronchial responses to inhaled histamine in 12 subjects with asthma." | 5.06 | Effects of SK&F 104353, a leukotriene receptor antagonist, on the bronchial responses to histamine in subjects with asthma: a comparative study with terfenadine. ( Dinh Xuan, AT; Lockhart, A; Marsac, J; Regnard, J; Rey, J; Similowski, T, 1990) |
"In a double blind, randomised, placebo controlled trial in a group of extrinsic asthmatics, we have evaluated the potency and selectivity of ebastine, a new piperidine-type H1-receptor antagonist, against histamine and methacholine-induced bronchoconstriction." | 5.06 | Dose-response relationship of the H1-histamine antagonist, ebastine, against histamine and methacholine-induced bronchoconstriction in patients with asthma. ( Holgate, ST; Wood-Baker, R, 1990) |
"Bronchial histamine provocation tests were performed in nine patients with nonallergic asthma on four consecutive days 45 minutes after inhalation of placebo or ipratropium bromide in a dose-response manner (40 micrograms, 200 micrograms, and 800 micrograms)." | 5.06 | Airways responses to ipratropium bromide do not vary with time in asthmatic subjects. Studies of interindividual and intraindividual variation of bronchodilatation and protection against histamine-induced bronchoconstriction. ( Ihre, E; Larsson, K, 1990) |
" In a randomized, double-blind, crossover study, we evaluated the effects of loratadine, 10 and 20 mg, and placebo administered once daily for 3 days on the skin-wheal responses to histamine, the airway responses to inhaled histamine and methacholine, and the skin-wheal and airway responses to allergen in 12 subjects with asthma." | 5.06 | Comparison of the effect of loratadine on the airway and skin responses to histamine, methacholine, and allergen in subjects with asthma. ( Holgate, ST; Town, GI, 1990) |
"We have investigated the ability of salbutamol to protect against bronchoconstriction induced by methacholine, histamine, and adenosine 5'-monophosphate (AMP) in nine subjects with asthma." | 5.06 | Comparative protective effect of the inhaled beta 2-agonist salbutamol (albuterol) on bronchoconstriction provoked by histamine, methacholine, and adenosine 5'-monophosphate in asthma. ( Finnerty, JP; Holgate, ST; Phillips, GD, 1990) |
"It was recently reported that caffeine may reduce the clinical symptoms of asthma and may prevent the clinical manifestations of this disease." | 5.06 | Effect of caffeine on histamine bronchoprovocation in asthma. ( Bertolo, L; Cohen, C; Colacone, A; Kreisman, H; Wolkove, N, 1990) |
"Inhaled adenosine 5'-monophosphate (AMP) induces bronchoconstriction in subjects with asthma, probably caused by histamine release from airway mast cells, and repeated AMP bronchial challenge leads to attenuation of the bronchoconstrictor response." | 5.06 | Repeated exposure of asthmatic airways to inhaled adenosine 5'-monophosphate attenuates bronchoconstriction provoked by exercise. ( Finnerty, JP; Holgate, ST; Polosa, R, 1990) |
"Twenty two subjects (10 normals, nine asthmatics and three who had suggestive histories for asthma but normal bronchial histamine challenges) underwent nasal challenges with logarithmic incremental doses of histamine or saline on alternate days." | 5.06 | Lack of airway response to nasal irritation in normal and asthmatic subjects. ( Levi, CR; Olson, LG; Saunders, NA; Tyler, GR, 1990) |
"Nitrendipine was given to eight patients with chronic stable asthma prior to a histamine challenge study and compared in a double-blind cross-over fashion with placebo." | 5.06 | Nitrendipine therapy in asthmatic subjects. ( Cormie, P; Harvey, J; Marley, JE; Mulloy, EM, 1990) |
"The effects of twice daily inhaled beclomethasone dipropionate (BDP) at two dose levels (500 and 1,000 micrograms daily) on the airway responsiveness to inhaled histamine was evaluated by a randomized, single-blind, cross-over study in 10 patients with stable asthma." | 5.06 | Dose-related effect of beclomethasone dipropionate on airway responsiveness in asthma. ( Baldanza, C; Bonanno, CT; Carpentiere, G; Castello, F; Marino, S, 1990) |
"In a study designed to determine the protective effect of the specific histamine H1 antagonist terfenadine on hypertonic saline induced bronchoconstriction, 10 asthmatic subjects underwent hypertonic saline challenge (3." | 5.06 | Role of histamine release in hypertonic saline induced bronchoconstriction. ( Belcher, NG; Lee, TH; O'Hickey, SP; Rees, PJ, 1989) |
"Inhalation of an aerosolized solution of lysine-aspirin has previously been described as a safer technique than oral challenge with aspirin for the diagnosis of aspirin-sensitive asthma." | 5.06 | Inhaled lysine-aspirin as a bronchoprovocation procedure in aspirin-sensitive asthma: its repeatability, absence of a late-phase reaction, and the role of histamine. ( Foord, R; Holgate, ST; Phillips, GD, 1989) |
"2 mg three times daily), both administered by powder inhaler, on bronchial hyperresponsiveness (BHR) to histamine in children, aged 7 to 15 years with mild stable asthma and limited bronchoconstriction who had a highly increased BHR." | 5.06 | Long-term effect of ipratropium bromide and fenoterol on the bronchial hyperresponsiveness to histamine in children with asthma. ( Kerrebijn, KF; Mulder, P; Raes, M, 1989) |
"Seventeen patients with perennial asthma, stable on a moderate dose of inhaled steroid, participated in a crossover study comparing the clinical effect of a non-sedative, potent and highly selective H1 antagonist (loratadine 10 mg) with placebo." | 5.06 | Effect of a non-sedative antihistaminic (loratadine) in moderate asthma. A double-blind controlled clinical crossover-trial. ( Dirksen, A; Engel, T; Frølund, L; Heinig, JH; Svendsen, UG; Weeke, B, 1989) |
"Inhaled adenosine and adenosine 5'-monophosphate (AMP) cause bronchoconstriction in atopic and nonatopic asthmatics by a mechanism believed to involve histamine release from airway mast cells and an interaction with neural reflexes." | 5.06 | The effect of oral terfenadine alone and in combination with flurbiprofen on the bronchoconstrictor response to inhaled adenosine 5'-monophosphate in nonatopic asthma. ( Holgate, ST; Phillips, GD, 1989) |
"Percentage reductions in the peak flow rates to a standardized number of histamine inhalations were compared after 7 days of treatment with 10 mg bd tazifylline and after 7 days of placebo in a randomized crossover study in 11 male seasonal atopic asthmatics." | 5.06 | The reducing effects of tazifylline on histamine-induced bronchoconstriction in atopic asthmatics. ( Harlow, B; Kiviranta, K; Reuter, C; Scott, J; Stenius-Aarniala, B, 1989) |
"A double-blind crossover study of the effects of real and placebo acupuncture on bronchial reactivity to histamine was carried out on 16 patients with moderately severe asthma." | 5.06 | Comparison of real and placebo acupuncture in histamine-induced asthma. A double-blind crossover study. ( Soh, PF; Tandon, MK, 1989) |
"5% saline was compared to the response to histamine and isocapneic hyperventilation in a group of children with mild asthma and control subjects." | 5.06 | Inhalation of hypertonic saline as a bronchial challenge in children with mild asthma and normal children. ( Araki, H; Sly, PD, 1989) |
"Inhaled topical lidocaine, used to produce anesthesia of the respiratory tract prior to bronchoscopy, may cause bronchoconstriction in asthmatic patients." | 5.06 | Lidocaine-induced bronchoconstriction in asthmatic patients. Relation to histamine airway responsiveness and effect of preservative. ( McAlpine, LG; Thomson, NC, 1989) |
"Eight subjects with asthma inhaled on separate occasions leukotriene E4 (LTE4) (6." | 5.06 | The effects of inhaled leukotriene E4 on the airway responsiveness to histamine in subjects with asthma and normal subjects. ( Arm, JP; Lee, TH; Spur, BW, 1988) |
" To evaluate this oral drug's efficacy in treating asthma, we examined the bronchodilator effects of 5-, 10-, and 20-mg doses as well as the protective effects of these doses against histamine-provoked bronchospasm." | 5.06 | Cetirizine inhibition of histamine-induced bronchospasm. ( Brik, A; Gong, H; Tashkin, DP, 1987) |
"The effect of flurbiprofen, a potent cyclo-oxygenase inhibitor, on histamine and methacholine reactivity was assessed in seven atopic subjects with asthma." | 5.06 | Effects of a cyclo-oxygenase inhibitor, flurbiprofen, and an H1 histamine receptor antagonist, terfenadine, alone and in combination on allergen induced immediate bronchoconstriction in man. ( Curzen, N; Holgate, ST; Rafferty, P, 1987) |
" Subjects with mild asthma were investigated to determine the course of change in bronchial responsiveness, measured as the provocative dose (PD20) of histamine that caused a 20% fall in forced expiratory volume in 1 s after short-term and longer term treatment with an inhaled beta-agonist." | 5.06 | Rebound increase in bronchial responsiveness after treatment with inhaled terbutaline. ( Britton, JR; Higgins, BG; Knox, AJ; Tattersfield, AE; Vathenen, AS, 1988) |
" The effects of pretreatment with clonidine and rilmenidine, a new alpha 2-adrenoceptor agonist, on the bronchial responses to inhaled histamine were studied on 3 different days in a controlled, double-blind, randomized study in 12 asymptomatic asthmatic subjects." | 5.06 | Comparative effects of rilmenidine and clonidine on bronchial responses to histamine in asthmatic subjects. ( Advenier, C; Dinh Xuan, AT; Lockhart, A; Matran, R; Regnard, J; Vitou, P, 1988) |
"Bronchial mucociliary clearance (CB) and tracheal mucus velocity (TMV) were measured during the course of repeated inhalations of histamine in six subjects with asthma who had no symptoms in a double-blind, crossover study with a radioaerosol technique." | 5.06 | Lung mucociliary transport in asymptomatic asthma: effects of inhaled histamine. ( Garrard, CS; Lourenço, RV; Mussatto, DJ, 1989) |
"We studied 14 patients with cystic fibrosis (CF) who had evidence of bronchial hyperreactivity on a standardized histamine challenge." | 5.06 | Mechanisms of bronchial hyperreactivity in cystic fibrosis. ( Allen, H; Manglick, P; Van Asperen, PP, 1988) |
"The effect of a potent inhibitor of angiotensin-converting enzyme, ramipril, was studied on both inhaled histamine and bradykinin-induced bronchoconstriction in six male, normotensive, mild asthmatic subjects." | 5.06 | The effect of an angiotensin converting enzyme inhibitor, ramipril, on bronchial responses to inhaled histamine and bradykinin in asthmatic subjects. ( Barnes, PJ; Dixon, CM; Fuller, RW, 1987) |
"The effect of pretreatment with nifedipine 20 mg sublingually on the bronchoconstrictor response to inhaled histamine and methacholine in asthmatic and normal subjects has been studied." | 5.06 | The effect of nifedipine on bronchial reactivity to inhaled histamine and methacholine: a comparative study in normal and asthmatic subjects. ( Costello, JF; Henderson, AF, 1988) |
" The protective effects of oral trifluoperazine (TFP) (7 mg) against standardized methacholine and histamine inhalation tests (MIT and HIT) were examined 2 and 22 h post-treatment in eight stable asthmatics using a randomized double-blind protocol." | 5.06 | The effect of trifluoperazine on bronchial responsiveness in asthma. ( Bowden, JJ; Crockett, AJ; Latimer, KM; Ruffin, RE, 1988) |
"The effect of cromolyn sodium (CS) pressurized aerosol on bronchial hyperreactivity was assessed by comparison with placebo in a double-blind crossover study of 14 adult patients with clinically stable asthma." | 5.06 | A controlled study on the effect of treatment with cromolyn sodium pressurized aerosol on bronchial reactivity in patients with asthma. ( Laitinen, LA; Poppius, H; Venho, K, 1986) |
"Single-dose salbutamol (200 micrograms), beclomethasone dipropionate (200 micrograms), and sodium cromoglycate (SCG) (10 mg) administered by inhalation 10 minutes before allergen challenge were examined with regard to inhibition of allergen-induced early (EAR) and late (LAR) asthmatic responses and allergen-induced increase in bronchial responsiveness to inhaled histamine." | 5.06 | Comparative effects of inhaled salbutamol, sodium cromoglycate, and beclomethasone dipropionate on allergen-induced early asthmatic responses, late asthmatic responses, and increased bronchial responsiveness to histamine. ( Cockcroft, DW; Murdock, KY, 1987) |
"Eight nonsmoking subjects with asthma, nonresponsive to the bronchoconstrictive effect of oral propranolol, were studied." | 5.06 | Increased responsiveness to histamine after propranolol in subjects with asthma nonresponsive to the bronchoconstrictive effect of propranolol. ( Carpentiere, G; Castello, F; Marino, S, 1988) |
"Changes in airway responsiveness to histamine after allergen inhalation challenge were studied in 14 nonsmoking atopic adult subjects with asthma." | 5.06 | Increases in airway responsiveness to histamine precede allergen-induced late asthmatic responses. ( Benson, MK; Cookson, WO; Craddock, CF; Durham, SR, 1988) |
"Histamine tachyphylaxis develops with repeated inhalation of histamine in asthmatic subjects, and this appears to be due to the release of inhibitory prostaglandins." | 5.06 | A new role for histamine H2-receptors in asthmatic airways. ( Jackson, PJ; Manning, PJ; O'Byrne, PM, 1988) |
"To determine the role of Na/K ATPase in determining bronchial reactivity in man, we studied the effect of 1 mg inhaled ouabain on histamine reactivity in six normal and 10 asthmatic subjects in a placebo controlled, crossover study." | 5.06 | The effect of inhaled ouabain on bronchial reactivity to histamine in man. ( Britton, JR; Knox, AJ; Tattersfield, AE, 1988) |
"We evaluated the efficacy of an oral dosage form of the investigational smooth muscle relaxant, zindotrine, a novel pyridazine derivative, in counteracting histamine-induced bronchospasm in a group of 12 non-medicated asymptomatic asthmatics." | 5.06 | The effect of oral zindotrine (MDL-257), a bronchial smooth muscle relaxant, on histamine airways responsiveness in asymptomatic asthmatics. ( Bangs, SE; Barker, KB; Diamond, L; Gordon, EE; Küng, M, 1987) |
"We have compared bronchial challenge with both histamine and methacholine for the tidal breathing method and dosimeter method, using the DeVilbiss 646 nebulizer, in 18 patients with asthma." | 5.06 | A comparison of histamine and methacholine bronchial challenges using the DeVilbiss 646 nebulizer and the Rosenthal-French dosimeter. ( Bennett, JB; Davies, RJ, 1987) |
"This study was performed in a randomized double-blind manner on 6 separate days in 10 asthmatic patients to investigate the effect of a sustained theophylline on baseline bronchial hyperreactivity to histamine in relation to the theophylline serum levels and the degree of bronchodilatation produced." | 5.06 | Relationship of serum theophylline concentrations to histamine-induced bronchospasm. ( Ciccarello, C; Crimi, N; Distefano, SM; Mistretta, A; Oliveri, R; Palermo, B; Palermo, F; Vancheri, C, 1987) |
"The bronchial responsiveness of a group of asthmatic children was studied using histamine stimulation after a single dose of theophylline and after placebo." | 5.06 | Protective effect of theophylline on histamine-induced bronchoconstriction in asthmatic children. ( Levene, S; McKenzie, SA, 1986) |
"The airway and cardiovascular effects of separate single oral doses of 50, 100 and 200 mg of bucindolol were compared to those of placebo in a double-blind trial in 16 patients with mild to moderately severe asthma." | 5.06 | The effect of bucindolol on the airway function of asthmatics. ( Alpers, JH; Crockett, AJ; Ruffin, RE, 1986) |
"We investigated the possibility that clonidine, an alpha 2-adrenoceptor agonist, can reduce the wheal-and-flare reactions induced by intradermal injections of allergen in patients with extrinsic asthma." | 5.06 | Inhibitory effects of clonidine on the allergen-induced wheal-and-flare reactions in patients with extrinsic asthma. ( Andersson, RG; Brundin, A; Lindgren, BR, 1987) |
"The effects of inhaled MgSO4 on histamine bronchoprovocation test (BPT) were studied in nine asthmatics in clinical remission (FEV1 greater than 80% of predicted)." | 5.06 | Reduction of histamine-induced bronchoconstriction by magnesium in asthmatic subjects. ( Arossa, W; Bucca, C; Bugiani, M; Rolla, G; Spinaci, S, 1987) |
"Nasal deposition of allergen or histamine could cause bronchoconstriction in subjects with asthma by a reflex mechanism." | 5.06 | Pulmonary response to nasal-challenge testing of atopic subjects with stable asthma. ( Cota, KA; Schumacher, MJ; Taussig, LM, 1986) |
"The influence of circulating noradrenaline on bronchial reactivity to histamine was investigated in eight asthmatic patients." | 5.06 | No influence of circulating noradrenaline on bronchial reactivity to histamine in asthmatic patients. ( Hjemdahl, P; Larsson, K, 1986) |
"We have investigated the effect of nifedipine on acetylcholine-induced bronchoconstriction in 8 asthmatics and on histamine-induced bronchoconstriction in another 8 asthmatics on a single-blind basis." | 5.06 | Effect of nifedipine on dose-response curves to acetylcholine and histamine measured during quiet breathing. ( Arai, M; Fueki, R; Kobayashi, S; Kuroiwa, H; Tomioka, S, 1986) |
"The reproducibility of the histamine challenge in seven asymptomatic patients with extrinsic asthma, provoked four times each with 1-2 weeks interval, was investigated." | 5.05 | Histamine-induced bronchospasm. Its reproducibility and usage in clinical evaluation of the sub-threshold bronchodilating dose of a new beta-agonist, KWD 2131. ( Hegardt, B; Löwhagen, O; Svedmyr, N, 1980) |
"The effect of an H1 antihistamine, an H2 antihistamine, and the combination of the two drugs on both histamine-induced bronchoconstriction and dermal whealing was examined in five patients with mild asthma." | 5.05 | A comparison of the actions of H1 and H2 antihistamines on histamine-induced bronchoconstriction and cutaneous wheal response in asthmatic patients. ( Nathan, RA; Schocket, AL; Segall, N, 1981) |
"The effect of prazosin, a potent and specific alpha 1-adrenoceptor antagonist given by inhalation (total nebulized 2 mg) was compared with placebo in a double-blind randomized study of 10 atopic asthmatic children." | 5.05 | Prazosin, an alpha 1-adrenoceptor antagonist, partially inhibits exercise-induced asthma. ( Barnes, PJ; Vickers, H; Wilson, NM, 1981) |
"Vasoactive intestinal peptide (VIP) caused significant bronchodilatation in seven asthmatic volunteers when given intravenously at the rate of 6 pmol/kg/min for 15 min during a double-blind study." | 5.05 | Vasoactive intestinal peptide causes bronchodilatation and protects against histamine-induced bronchoconstriction in asthmatic subjects. ( Morice, A; Sever, PS; Unwin, RJ, 1983) |
"Eight asthmatic patients and two normal subjects performed two identical exercise tests 140 minutes apart (first test preceded by inhalation of saline and the second by terbutaline sulphate)." | 5.05 | Arterial plasma histamine levels at rest, and during and after exercise in patients with asthma: effects of terbutaline aerosol. ( Anderson, SD; Bye, PT; Ferris, L; Schoeffel, RE; Seale, JP; Taylor, KM, 1981) |
"To evaluate the effect of negative ionisation of inspired air on bronchial reactivity, 11 asthmatic children were challenged twice by exercise and 10 were challenged twice by histamine inhalation." | 5.05 | Effect of negative ionisation of inspired air on the response of asthmatic children to exercise and inhaled histamine. ( Amirav, I; Amitai, I; Bar-Yishay, E; Ben-Dov, I; Godfrey, S; Shochina, M, 1983) |
" In 8 asthmatic subjects, dose-response curves were determined to isocapnic hyperventilation of cold air 30 min after inhalation of chlorpheniramine maleate (18 mg nebulized during tidal breathing), 2 doses of atropine sulphate (3 mg and 18 mg nebulized), or placebo." | 5.05 | The protective effect of inhaled chlorpheniramine and atropine on bronchoconstriction stimulated by airway cooling. ( Daniel, EE; Hargreave, FE; Morris, M; O'Byrne, PM; Roberts, RS; Thomson, NC, 1983) |
"Eight young men with documented exercise-induced asthma each performed two standard exercise tests and underwent two histamine challenges on separate days after double blind administration of either 20 mg nifedipine or placebo." | 5.05 | Nifedipine in the prevention of asthma induced by exercise and histamine. ( Corris, PA; Gibson, GJ; Nariman, S, 1983) |
"Ten asthmatic children who gave a history of cough or wheeze after orange drinks, were tested for tartrazine sensitivity." | 5.05 | Oral tartrazine challenge in childhood asthma: effect on bronchial reactivity. ( Dixon, C; Hariparsad, D; Silverman, M; Wilson, N, 1984) |
"The effects of a therapeutic serum theophylline concentration on inhaled methacholine and histamine were studied in 8 stable, moderately severe asthmatic children 8 to 15 yr of age." | 5.05 | Effects of theophylline on inhaled methacholine and histamine in asthmatic children. ( Howick, J; Kelly, HW; McWilliams, BC; Menendez, R, 1984) |
" We have investigated the effect of VIP on bronchomotor tone and bronchial responsiveness to inhaled histamine in 6 atopic asthmatic subjects." | 5.05 | The effect of inhaled vasoactive intestinal peptide on bronchial reactivity to histamine in humans. ( Barnes, PJ; Dixon, CM, 1984) |
" Five stable adult atopic asthmatics received inhalation tests with histamine on 2 days after both placebo and a dose of atropine sulphate (18 mg nebulized during tidal breathing), which reduced saliva output." | 5.05 | The effect of atropine on allergen-induced increases in bronchial responsiveness to histamine. ( Boulet, LP; Cockcroft, DW; Daniel, EE; Hargreave, FE; Juniper, EF; Latimer, KM; Roberts, RS; Thomson, NC, 1984) |
"Parenterally administered diphemanil methylsulfate, a quarternary ammonium compound with both parasympatholytic and direct bronchial smooth muscle relaxing properties, has been found effective in the treatment of bronchial asthma." | 5.05 | Effect of inhaled diphemanil methylsulfate, a parasympatholytic agent, on histamine induced bronchoconstriction in asymptomatic asthmatics. ( Diamond, L; Küng, M, 1984) |
"The excretion of histamine (Hi) and it metabolite methyhistamine (MeHi) was determined in separated fractions of urine up to 12h after standardized allergen provocations in 18 adult patients with defined extrinsic bronchial asthma." | 5.05 | Studies on histamine metabolism in allergen-induced asthma. ( Granerus, G; Löwhagen, O; Wetterqvist, H, 1980) |
"Ten asthmatic children with a history of cough and wheeze after drinking a cola drink performed histamine inhalation tests before and 30 minutes after a drink of Pepsi-Cola, soda water, and water on three separate study days." | 5.05 | Objective test for food sensitivity in asthmatic children: increased bronchial reactivity after cola drinks. ( silverman, M; Taylor, G; Vickers, H; Wilson, N, 1982) |
"Inhalation histamine challenges were performed in groups of normal and asthmatic subjects." | 5.05 | Prostaglandins and the control of airways responses to histamine in normal and asthmatic subjects. ( Walters, EH, 1983) |
"We compared the effects of two histamine receptor blocking agents, chlorpheniramine (H1) and cimetidine (H2) on the airways of healthy and asthmatic subjects." | 5.05 | Histamine blocking agents in healthy and asthmatic subjects. ( Brown, S; Gerstenhaber, B; Lach, E; Schachter, EN, 1982) |
"The degree of protection against inhaled histamine achieved by inhalation of the ganglion blocker hexamethonium bromide plus placebo, hexamethonium plus atropine sulphate, and placebo plus placebo was examined in six atopic subjects, four of whom had current asthma." | 5.05 | The effect of inhaled hexamethonium bromide and atropine sulphate on airway responsiveness to histamine. ( Daniel, EE; Hargreave, FE; Latimer, KM; Morris, MM; O'Byrne, PM; Roberts, RS; Thomson, NC, 1985) |
"Plasma histamine and serum neutrophil chemotactic activity (S-NCA) were measured in ten atopic asthmatic patients on four separate occasions after allergen bronchial provocation testing (BPT)." | 5.05 | Circulating histamine and neutrophil chemotactic activity during allergen-induced asthma: the effect of inhaled antihistamines and anti-allergic compounds. ( Cundell, DR; Davies, RJ; Moodley, I; Morgan, DJ; Sheinman, BD; Smart, W, 1985) |
"This study was designed to assess the acute effect of 1 mg of orally administered ketotifen on the dose-response curve to both histamine and methacholine, in 15 patients with bronchial asthma." | 5.05 | Acute effect of ketotifen on the dose-response curve of histamine and methacholine in asthma. ( Barja, S; Cruz, E; Ferretti, R; Lisboa, C; Moran, J; Moreno, R; Sanchez, I, 1985) |
" The degree of protection by JO28 against histamine and methacholine-induced bronchospasm has been investigated in 20 asthmatic patients with serious airways hyper-reactivity." | 5.05 | Protective effect by UCB JO28 against histamine and methacholine induced bronchial hyperreactivity. ( Baltes, E; Maesen, FP; Rihoux, JP; Smeets, JJ, 1985) |
"In order to compare long-term changes induced on a wide spectrum of bronchial hyperreactivity (BH) by the antiallergic drugs disodium cromoglycate (DSCG) and ketotifen, 56 asthmatic patients (age range 15-55 years) were studied." | 5.05 | Long-term modification on histamine-induced bronchoconstriction by disodium cromoglycate and ketotifen versus placebo. ( Colas Sanz, C; de Barrio Fernandez, M; Gozalo Reques, F; Herrero Lopez, T; Rubio Sotes, M; Senent Sanchez, C, 1985) |
"The airway response to increasing concentrations of inhaled-adenosine and histamine after oral theophylline or matched placebo was studied in nine asthmatic subjects." | 5.05 | Specific antagonism of adenosine-induced bronchoconstriction in asthma by oral theophylline. ( Holgate, ST; Mann, JS, 1985) |
"We performed a double-blind crossover study to compare the effects of long-term treatment of inhaled budesonide and terbutaline on bronchial hyperreactivity in 17 patients with allergic asthma." | 5.05 | Changes in bronchial hyperreactivity induced by 4 weeks of treatment with antiasthmatic drugs in patients with allergic asthma: a comparison between budesonide and terbutaline. ( de Vries, K; Koëter, GH; Kraan, J; Sluiter, HJ; vd Mark, TW, 1985) |
"We have administered nifedipine by aerosol to six patients with mild asthma to determine whether local administration of a potent calcium channel blocker has any effect on resting airway tone or histamine reactivity." | 5.05 | The effect of inhaled nifedipine on bronchial reactivity to histamine in man. ( Barnes, PJ; Cuss, FM, 1985) |
"The protective anti-asthmatic effect of a new anti-allergic drug with histaminolytic and anti-anaphylactic properties was tested in various controlled clinical studies of induced bronchospasm in asthmatic patients (provocation tests using a histamine aerosol, and exercise-induced asthma using a bicycle ergometer)." | 5.04 | [Drug prevention of bronchial asthma: inhibition of histamine and exercise-induced asthma by a new anti-anaphylactic oral preparation (ketotifen) (author's transl)]. ( Radielovic, P; Wüthrich, B, 1978) |
"1 Two studies have been carried out to investigate the effect of H1- and H2-receptor blocking agents on histamine-induced bronchoconstriction in non-asthmatic subjects." | 5.04 | Effects of H1- and H2-receptor blocking agents on histamine-induced bronchoconstriction in non-asthmatic subjects. ( Maconochie, JG; Richards, DA; Woodings, EP, 1979) |
"In a double-blind, within-patient, randomized study, 12 mild asthmatics were given single oral doses of propranolol (80 mg), metoprolol (100 mg), timolol (10 mg), or placebo." | 5.04 | Selectivity of beta adrenoreceptor antagonist drugs assessed by histamine bronchial provocation. ( Anderton, RC; Frith, PA; Hargreave, FE; Kumana, CR; Newhouse, MT; Ruffin, RE, 1979) |
"This study was designed to examine the effect of an H1 antihistamine, chlorpheniramine, an H2 antihistamine, cimetidine, and the combination of chlorpheniramine and cimetidine on histamine-induced bronchoconstriction in a double-blind, randomized protocol on 11 patients with asthma." | 5.04 | The effects of H1 and H2 antihistamines on histamine inhalation challenges in asthmatic patients. ( Glover, GC; Nathan, RA; Schocket, AL; Segall, N, 1979) |
"The effect of inhalation of 2 per cent solution of sodium cromoglycate compared to that of saline on the bronchial response to methacholine and histamine was studied in 30 asthmatic children." | 5.04 | Sodium cromoglycate-induced changes in the dose-response curve of inhaled methacholine and histamine in asthmatic children. ( Kattan, M; Levison, H; Woenne, R, 1979) |
"To assess further the bronchodilator activity of inhaled antihistamines ten stable asthmatic subjects inhaled aerosols of clemastine, 1 mg/ml, and saline placebo administered double blind." | 5.04 | Inhaled antihistamines--bronchodilatation and effects on histamine- and methacholine-induced bronchoconstriction. ( Bevan, C; Nogrady, SG, 1978) |
"In twenty adult asthmatics studied in a stable state, histamine bronchial challenges were carried out at one-week intervals with the Wright nebulizer and with the dosimeter-DeVilbiss apparatus." | 5.04 | Comparison of histamine bronchial challenges with the Wright nebulizer and the dosimeter. ( Beaupré, A; Malo, JL, 1979) |
" Indomethacin had no effect on day-to-day asthmatic symptoms, or challenge-induced asthma, suggesting that prostaglandins are not fundamental to the pathogenesis of asthma." | 5.04 | The response of normal and asthmatic subjects to prostaglandins E2 and F2alpha by different routes, and their significance in asthma. ( Cuthbert, MF; Smith, AP, 1976) |
"Out of 19 patients with extrinsic bronchial asthma challenged with 123 mug histamine acid phosphate by intravenous infusion only 13 responded with a fall in FEV1 of over 10% (mean 16%)." | 5.04 | Bronchial reactivity to histamine before and after sodium cromoglycate in bronchial asthma. ( Kang, B; Lee, CK; Miller Kolotkin, B; Townley, RG, 1976) |
"The action mechanism of cromolyn sodium and its effect on bronchial sensitivity to allergen, methacholine chloride, and histamine inhalations were studied in 17 asthmatic subjects." | 5.04 | Cromolyn therapy in patients with bronchial asthma. Effect on inhalation challenge with allergen, histamine, and methacholine. ( Kang, B; Ryo, UY; Townley, RG, 1976) |
"The influence on airway conductance of inhaled aerosols of prostaglandin F(2)alpha (PGF(2)alpha), histamine, and prostaglandin E(2) (PGE(2)) was studied in 10 patients with spirometrically reversible bronchial asthma and in 10 healthy subjects with no history of lung disorder." | 5.04 | Bronchial hyperreactivity to prostaglandin F 2 and histamine in patients with asthma. ( Hedqvist, P; Holmgren, A; Mathé, AA; Svanborg, N, 1973) |
" Histamine is a central mediator released from mast cells through allergic reactions." | 5.01 | The Role of Histamine in the Pathophysiology of Asthma and the Clinical Efficacy of Antihistamines in Asthma Therapy. ( Ogasawara, M; Yamauchi, K, 2019) |
"Histamine is an important endogenous signaling molecule that is involved in a number of physiological processes including allergic reactions, gastric acid secretion, neurotransmitter release, and inflammation." | 4.91 | Functional Profiling of 2-Aminopyrimidine Histamine H4 Receptor Modulators. ( Savall, BM; Thurmond, RL; Tichenor, MS; Venable, JD, 2015) |
"Airway hyperresponsiveness (AHR) is a characteristic feature of asthma, and its measurement using direct inhalation challenges, particularly with inhaled methacholine or histamine, or indirect challenges using stimuli such as exercise, dry air hyperpnea, distilled water, hypertonic saline and mannitol, and the pharmacological agent adenosine monophosphate is important in establishing a correct diagnosis." | 4.90 | Bronchoprovocation tests in asthma: direct versus indirect challenges. ( Leuppi, JD, 2014) |
"Histamine has been reported to play an important role in pathogenesis of bronchial asthma." | 4.87 | [Roles of histamine in the pathogenesis of bronchial asthma and reevaluation of the clinical usefulness of antihistamines]. ( Kobayashi, H; Maeyama, K; Nakamura, Y; Ogasawara, M; Shikanai, T; Yamauchi, K, 2011) |
"The histamine H4 receptor is expressed preferentially on immune cells, indicating a possible role of the H4 receptor in inflammation." | 4.86 | Does the histamine H4 receptor have a pro- or anti-inflammatory role in murine bronchial asthma? ( Beermann, S; Neumann, D; Seifert, R, 2010) |
"Histamine plays a key role in the morbidity and mortality associated with allergy, asthma, gastric ulcers, anaphylaxis, sepsis, hemorrhagic shock, anesthesia, surgery, cardiovascular disease, cancer, CNS disorders, and immune-mediated disease." | 4.85 | Histamine: metabolism, physiology, and pathophysiology with applications in veterinary medicine. ( Kovacic, JP; Peters, LJ, 2009) |
"Cumulative clinical and laboratory evidence on histamine and its actions suggests that it has a pathophysiologic role in asthma." | 4.81 | Role of histamine in the pathophysiology of asthma: immunomodulatory and anti-inflammatory activities of H1-receptor antagonists. ( Gelfand, EW, 2002) |
"H1 antihistamines are widely used in the treatment of conditions such as seasonal and perennial allergic rhinitis, urticaria and angioedema, as well as being an adjunct therapy for anaphylaxis." | 4.80 | Assessment of antihistamine efficacy and potency. ( Howarth, PH, 1999) |
"Airway hyperresponsiveness to histamine is a hallmark of asthma, and histamine inhalation reproduces asthma symptoms." | 4.80 | Is antihistamine (H1-receptor antagonist) therapy useful in clinical asthma? ( Simons, FE, 1999) |
"Histamine plays a critical role in the pathogenesis of bronchial asthma." | 4.79 | [Regulation of gene expression of L-histidine decarboxylase and histamine N-methyl-transferase, and its relevance to the pathogenesis of bronchial asthma]. ( Yamauchi, K, 1996) |
"Antihistamines were investigated for use in asthma shortly after discovery over fifty years ago." | 4.79 | Antihistamines in the treatment of asthma. ( Grant, JA; Malick, A, 1997) |
"097 mg/ml for histamine, which clearly reveals bronchial hyperreactivity." | 4.78 | [Transient syndrome of acute irritation of the bronchi induced by single and massive inhalation of phthalic anhydride]. ( Frans, A; Pahulycz, C, 1993) |
"Histamine is an important mediator of asthma." | 4.78 | Antihistamines in the treatment of asthma. ( Bousquet, J; Godard, P; Michel, FB, 1992) |
"Release of inflammatory mediators such as histamine and products of arachidonic acid metabolism has been demonstrated in bronchoalveolar lavage fluid of patients with asthma." | 4.78 | Role of inflammatory mediators in asthma. ( Barnes, PJ; Chung, KF, 1992) |
"Because the older antihistamines possessed relatively weak antihistaminic action, as well as sedative and anticholinergic effects, they could not be administered in doses high enough to confer relief to atopic patients with asthma." | 4.78 | Antihistamines in the treatment of clinical asthma. ( Rafferty, P, 1990) |
"Anti-histamines are considered weakly effective in the treatment of asthma whether in acute exacerbations or as basic therapy." | 4.77 | [Asthma and synthetic antihistaminics]. ( Beaumont, D; Sapene, M; Taytard, A, 1987) |
"In addition to bronchial smooth muscle, histamine and other mediators act in bronchial asthma on the microcirculation of pulmonary connective tissue." | 4.77 | The role of histamine and other mediators in microvascular changes in acute inflammation. ( Movat, HZ, 1987) |
"Bronchial inhalation test with histamine or methacholine are useful to measure the presence and degree of nonallergic bronchial hyperresponsiveness, a ubiquitous feature of current symptomatic asthma." | 4.77 | Bronchial inhalation tests. I. Measurement of nonallergic bronchial responsiveness. ( Cockcroft, DW, 1985) |
"Xanthines, best represented by theophylline, constitute a pharmacological principle of considerable age and importance in the treatment of asthma." | 4.76 | Some pharmacological aspects of xanthines in asthma. ( Persson, CG, 1980) |
"Hydrogen-rich water has a significant protective effect on OGD/R-causing HT22 cell injury, and the mechanism may be related to the inhibition of autophagy." | 4.40 | Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19. ( , 2023) |
"Endogenous adenosine 5'-monophosphate (AMP), acetylcholine (ACh), and histamine (HA) are known to be important in bronchial contraction, but their clinical relevance to asthma is poorly understood." | 4.12 | Endogenous Adenosine 5'-Monophosphate, But Not Acetylcholine or Histamine, is Associated with Asthma Control, Quality of Life, and Exacerbations. ( Deng, K; Fang, XM; Huang, D; Li, WM; Liu, D; Liu, L; Liu, Y; Luo, FM; Oliver, BG; Wan, HJ; Wang, G; Wang, J; Wang, L; Zhang, HP; Zhang, L; Zhang, X, 2022) |
"To study the therapeutic potential of Antileukotriene drug- Camellia sinensis extract co-formulation on histamine induced asthma in guinea pigs." | 4.02 | Therapeutic Potential of Antileukotriene Drug- ( Kulkarni, GT; Kumar, Y; Singh, N, 2021) |
"In a physiological study EMGdi was recorded from esophageal electrode (EMGdi-e) in 16 asthma patients and 16 healthy subjects during a histamine challenge test." | 4.02 | Identifying bronchoconstriction from the ratio of diaphragm EMG to tidal volume. ( Chen, YY; He, BT; Jolley, C; Luo, Y; Luo, YM; Moxham, J; Polkey, ML; Steier, J; Wang, LS, 2021) |
"To observe the effect of moxibustion on respiratory function and contents of histamine and neuropeptides in skin tissue of "Feishu" (BL13) in asthmatic rats, so as to explore its mechanisms underlying improvement of asthma." | 3.96 | [Effect of moxibustion on respiratory function and cutaneous histamine and neuropeptide contents of "Feishu" (BL13) in asthmatic rats]. ( Pan, J; Qiu, RR; Wang, CX; Yang, RD; Zhang, C; Zhang, GS; Zhang, J, 2020) |
" In these patients, the total increase in IgE and blood eosinophilia, in 1,5 times increased blood histamine and the level of exhaled NO2 have been increased." | 3.91 | Allergic rhinitis and asthma co-morbidity. ( Sukhan, VS, 2019) |
"The rationale of this study is that, treatment of asthmatic Guinea pig with combined administration of Montelukast sodium and Green Tea Extract (GTE) as a single capsule will mitigate the inflammatory injury in the airways and weaken the asthmatic response." | 3.88 | Montelukast Sodium Formulation Containing Green Tea Extract to Reduce the Oxidative Stress in Guinea Pig Model of Chronic Allergic Asthma. ( Kulkarni, GT; Kumar, Y; Singh, N, 2018) |
"Adenosine monophosphate (AMP) may reflect airway inflammation and hyperresponsiveness, but relationship between AMP and histamine (His, a conventional stimulus) bronchial provocation test (BPT) in asthma is not fully elucidated." | 3.85 | Adenosine monophosphate is not superior to histamine for bronchial provocation test for assessment of asthma control and symptoms. ( An, JY; Gao, Y; Guan, WJ; Liu, WT; Wu, F; Xie, YQ; Yu, XX; Zheng, JP, 2017) |
" PRE treatment decreased mucus production in airway epithelium, inflammatory cell number, eosinophilia, type 2 cytokines, and histamine in bronchoalveolar lavage fluid (BALF)." | 3.85 | Reduced allergic lung inflammation by root extracts from two species of Peucedanum through inhibition of Th2 cell activation. ( Chun, JM; Gu, GJ; Kim, HS; Kwon, BI; Lee, AR; Lee, AY, 2017) |
"This retrospective analysis was conducted considering the results of nonspecific bronchoprovocative test with histamine, skin tests to inhalant allergens and total IgE levels in the serum of asthmatic patients with controlled bronchial asthma." | 3.83 | The relation between nonspecific hyperreactivity of the airways and atopic constitution in asthmatics. ( Baletić, N; Novković, D; Petrović, M; Živković, V, 2016) |
"The following methods were used in experiments: the in-vitro tracheal smooth muscle contraction induced by histamine; the changes in specific airway resistance (sRaw) to histamine and the sensitivity of a chemically induced cough reflex both via an in-vivo method; the serum and BALF concentrations' analysis of the inflammatory cytokines interleukin IL-4, IL-5, IL-13; and lung tissue infiltration by eosinophils and mastocytes." | 3.83 | Bronchodilatory, antitussive and anti-inflammatory effect of morin in the setting of experimentally induced allergic asthma. ( Franova, S; Joskova, M; Kazimierova, I; Pappova, L; Plank, L; Sutovska, M, 2016) |
" To confirm the histamine-binding capacity of rHa24, a histamine-binding assay was completed in vitro (ELISA) and in vivo by inhibition of allergic asthma in mice." | 3.83 | Specific histamine binding activity of a new lipocalin from Hyalomma asiaticum (Ixodidae) and therapeutic effects on allergic asthma in mice. ( Cao, J; Gong, H; Li, Z; Wang, Y; Zhang, H; Zhou, J; Zhou, Y, 2016) |
"The commercially available alpha-asarone injections (CA-ARE) were frequently found to cause severe anaphylactic reactions by the solubilizer contained in the formulation such as polysorbate 80 and propylene glycol." | 3.81 | Systemic delivery of alpha-asarone with Kolliphor HS 15 improves its safety and therapeutic effect on asthma. ( Gong, T; Li, J; Li, M; Lu, H; Zhang, Z, 2015) |
" Furthermore, MCD-KV-10 was evaluated for in vitro lipoxygenase inhibition activity; in vivo mast cell stabilization potential and in vivo anti-asthmatic activity was done in ovalbumin-induced airway inflammation model in guinea pigs." | 3.81 | Implication of novel thiazolo-thiophene derivative (MCD-KV-10) for management of asthma. ( Dash, RP; Nivsarkar, M; Pandya, AN; Patil, D; Thakur, SK; Vasu, KK; Venkatesh, P, 2015) |
"Histamine is an important mediator in the pathophysiology of asthma." | 3.81 | Genetic variation within the histamine pathway among patients with asthma--a pilot study. ( Dai, H; Jones, BL; Raje, N; Vyhlidal, CA, 2015) |
"Via the histamine H4 -receptor (H4 R), histamine promotes the pathogenesis of experimental allergic asthma in mice." | 3.81 | The histamine H4 -receptor (H4 R) regulates eosinophilic inflammation in ovalbumin-induced experimental allergic asthma in mice. ( Glage, S; Hartwig, C; Munder, A; Neumann, D; Schenk, H; Seifert, R; Wedekind, D, 2015) |
"Ovalbumin inhalation caused early (EAR) and late asthmatic response (LAR), airway hyper-reactivity to histamine and influx of inflammatory cells into the lungs." | 3.81 | LPS exacerbates functional and inflammatory responses to ovalbumin and decreases sensitivity to inhaled fluticasone propionate in a guinea pig model of asthma. ( Broadley, KJ; Ford, WR; Kidd, EJ; Lowe, AP; Nials, AT; Thomas, RS, 2015) |
"Asthma, a common disorder that affects >250 million people worldwide, is defined by exaggerated bronchoconstriction to inflammatory mediators including acetylcholine (ACh), bradykinin and histamine-also termed airway hyper-responsiveness." | 3.81 | A fungal protease allergen provokes airway hyper-responsiveness in asthma. ( Balenga, NA; Chan, EC; Druey, KM; Jude, J; Klichinsky, M; Laviolette, M; Panettieri, RA; Xie, Z; Zhao, M, 2015) |
"Histamine is an important mediator in the pathogenesis of asthma." | 3.81 | Genetic Variation along the Histamine Pathway in Children with Allergic versus Nonallergic Asthma. ( Anvari, S; Dai, H; Jones, BL; Vyhlidal, CA, 2015) |
" Further, anti-asthmatic potential of curcumin, through intranasal route has been evaluated for the first time in LPS induced airway inflammation in an ovalbumin (OVA)-challenged mouse asthma model." | 3.81 | Lipopolysaccharide (LPS) exposure differently affects allergic asthma exacerbations and its amelioration by intranasal curcumin in mice. ( Dash, D; Kumari, A; Singh, R, 2015) |
"Histamine H1 receptor (H1R) antagonists and glucocorticoid receptor (GR) agonists are used to treat inflammatory conditions such as allergic rhinitis, atopic dermatitis and asthma." | 3.81 | Effects of histamine H1 receptor signaling on glucocorticoid receptor activity. Role of canonical and non-canonical pathways. ( Davio, C; Fernández, N; Fitzsimons, CP; Granja-Galeano, G; Monczor, F; Shayo, C; Zappia, CD, 2015) |
"We evaluated the inhibitory effects of flavone derivatives having the chromone moiety on the immediate-phase asthmatic response (IAR) and the late-phase asthmatic response (LAR) to aerosolized-ovalbumin (OA) exposure in conscious OA-sensitized guinea pigs." | 3.80 | Flavones derived from nature attenuate the immediate and late-phase asthmatic responses to aerosolized-ovalbumin exposure in conscious guinea pigs. ( Kim, CJ; Kim, JM; Lee, JY, 2014) |
"R group consistently displayed a transient antigen-induced airway obstruction (AI-AO) as well as AI-AHR, high T×A2, histamine, OVA-IgG1, OVA-IgE and OVA-IgA levels, and intense granulocyte infiltration." | 3.79 | Antigen-induced airway hyperresponsiveness in absence of broncho-obstruction in sensitized guinea pigs. ( Bazán-Perkins, B; Campos, MG; García-Zepeda, E; Martínez-Cordero, E; Ramos-Ramírez, P, 2013) |
"This study established asthma model induced by histamine phosphate and acetylcholine chloride (His&Ach) in guinea pigs, which then were administered orally with QFXY." | 3.79 | Qingfei Xiaoyan Wan alleviates asthma through multi-target network regulation. ( Bai, G; Cheng, B; Miao, Y; Pan, P; Wu, H; Zhao, Z, 2013) |
"Curcumin, a phytochemical present in turmeric, rhizome of Curcuma longa, has been shown to have a wide variety of pharmacological activities including anti-inflammatory, anti-allergic and anti-asthmatic properties." | 3.79 | Intranasal curcumin and its evaluation in murine model of asthma. ( Chauhan, PS; Chawla, R; Dash, D; Kumar, JP; Kumari, S; Singh, M; Singh, R, 2013) |
"A new nanomedicine consisting of chitosan/carboxymethyl-β-cyclodextrin loaded with unfractioned or low-molecular-weight heparin is described and its potential in asthma treatment is evaluated." | 3.78 | A potential nanomedicine consisting of heparin-loaded polysaccharide nanocarriers for the treatment of asthma. ( Alonso, MJ; Brea, J; Loza, MI; Oyarzun-Ampuero, FA; Torres, D, 2012) |
"FOT and spirometry were performed in 20 asthmatic children (aged 5-18 years) following aerosolized histamine and methacholine at an interval of 2 weeks." | 3.78 | Spirometry and forced oscillations in the detection of airway hyperreactivity in asthmatic children. ( Czövek, D; Novák, Z; Peták, F, 2012) |
"1 years) with established asthma (PC(20)FEV(1) histamine below 4 mg/ml) were included in this study." | 3.78 | Mannitol challenge does not confirm bronchial hyperreactivity in some histamine-responsive asthmatic children. ( Siergiejko, G; Siergiejko, Z; Swiebocka, EM, 2012) |
" We isolated caffeic acid and phenylpropanoid glycosides, 1-O-caffeoyl glycoside and acteoside [β-(3',4'-dihydroxyphenyl) ethyl-O-α-l-rhamnopyranosyl(1→3)-β-d-(4-O-caffeoyl)-glucopyranoside] from their ethylacetate fractions, respectively, and evaluated their anti-asthmatic effects on the aerosolized ovalbumin (OA) challenge in the OA-sensitized guinea-pigs measuring the specific airway resistance (sRaw) during the immediate-phase response (IAR) and late-phase response (LAR), and also measured recruitment of leukocytes and chemical mediators on the bronchoalveolar lavage fluids (BALF) in LAR, as well as histopathological survey." | 3.77 | Anti-asthmatic effects of phenylpropanoid glycosides from Clerodendron trichotomum leaves and Rumex gmelini herbes in conscious guinea-pigs challenged with aerosolized ovalbumin. ( Kim, CJ; Lee, JG; Lee, JY; Sim, SS; Whang, WK, 2011) |
"In the present study, the efficacy of β-sitosterol isolated from an n-butanol extract of the seeds of the plant Moringa oleifera (Moringaceae) was examined against ovalbumin-induced airway inflammation in guinea pigs." | 3.77 | Suppression of ovalbumin-induced Th2-driven airway inflammation by β-sitosterol in a guinea pig model of asthma. ( Mahajan, SG; Mehta, AA, 2011) |
"Experimental asthma model was established in Balb/c mice sensitized by ovalbumin (OVA), followed by aerosol allergen challenges." | 3.77 | Cortex Mori Radicis extract exerts antiasthmatic effects via enhancement of CD4(+)CD25(+)Foxp3(+) regulatory T cells and inhibition of Th2 cytokines in a mouse asthma model. ( Jeong, SJ; Kim, HJ; Kim, SH; Lee, HJ; Park, EJ, 2011) |
" Histamine and acetylcholine were used to guinea pigs to establish bronchospasm model." | 3.77 | Phytopharmacological evaluation and anti-asthmatic activity of Ficus religiosa leaves. ( Acharya, N; Acharya, S; Jasani, N; Kapoor, M; Kumar, V, 2011) |
" In the present study, the effects of nine phenolic compounds from GE on immediate-phase (IAR) and late-phase (LAR) asthmatic responses after aerosolized-ovalbumin (OA) challenge were evaluated by determining the specific airway resistance (sRaw) using a double-chambered plethysmograph in conscious guinea pigs with IgE-mediated asthma." | 3.76 | Anti-asthmatic activity of phenolic compounds from the roots of Gastrodia elata Bl. ( Jang, YW; Kim, CJ; Lee, JY, 2010) |
"ASHMI abolished EAR, which was associated with significantly reduced histamine, leukotriene C4, and OVA-specific IgE levels, as well as LAR, which was associated with significantly reduced bronchoalveolar lavage fluid (BALF) eosinophils, decreased airway remodeling, and lower Th2 cytokine levels in BALF and splenocyte cultures." | 3.76 | Pharmacology and immunological actions of a herbal medicine ASHMI on allergic asthma. ( Birmingham, N; Busse, P; Cao, J; Goldfarb, J; Li, XM; Srivastava, K; Wen, MC; Yang, N; Zhang, T, 2010) |
"Peripheral blood mononuclear cell from 15 rhinitic and 14 asthmatic HDM-allergic subjects and 16 controls were cultured with Der p 1 or histamine." | 3.76 | Histamine induces Th2 activation through the histamine receptor 1 in house dust mite rhinitic but not asthmatic patients. ( Botturi, K; Lacoeuille, Y; Magnan, A; Vervloet, D, 2010) |
"No subjects with EB responded to either AMP (n = 5) or mannitol (n = 7) while 4/8 and 7/10 subjects with asthma responded to the respective challenges (P = 0." | 3.76 | Mannitol and AMP do not induce bronchoconstriction in eosinophilic bronchitis: further evidence for dissociation between airway inflammation and bronchial hyperresponsiveness. ( Bradding, P; Brightling, CE; McKenna, S; Singapuri, A, 2010) |
"Hypertonic histamine challenge-induced cough and PC(20) are sensitive measures in assessing the treatment effect in asthma." | 3.76 | Assessment of inhaled corticosteroid treatment response in asthma using hypertonic histamine challenge-induced cough. ( Koistinen, T; Kontra, KM; Koskela, H; Peuhkurinen, K; Purokivi, M, 2010) |
"Patients with a former diagnosis of asthma and a positive histamine provocation test were re-examined to identify subjects with complete asthma remission (no asthma symptoms or medication, PC20 histamine > 32 mg/ml, FEV1 > 90% predicted)." | 3.76 | Can AMP induce sputum eosinophils, even in subjects with complete asthma remission? ( Broekema, M; Dijkstra, A; Hylkema, MN; Lodewijk, ME; Postma, DS; ten Hacken, NH; Timens, W; Volbeda, F, 2010) |
"Histamine and vascular endothelial growth factor (VEGF) have been implicated in the pathogenesis of allergic asthma; they enhance inflammation, vascular permeability, and mucus secretion." | 3.76 | Increased synthesis of vascular endothelial growth factor in allergic airway inflammation in histidine decarboxylase knockout (HDC(-/-)) mice. ( Falus, A; Kardos, M; Komlósi, ZI; Losonczy, G; Pállinger, E; Szabó, A; Szebeni, B; Sziksz, E; Tibor Kozma, G; Tulassay, T; Vannay, A, 2010) |
" The authors examined the correlation between airway remodeling and bronchial reactivity to histamine (Hist) and acetylcholine (ACh) in patients with moderate to severe asthma." | 3.76 | Bronchial reactivity to histamine is correlated with airway remodeling in adults with moderate to severe asthma. ( Akiyama, K; Mitomi, H; Oshikata, C; Saito, H; Sekiya, K; Takeichi, S; Tanimoto, H; Tsuburai, T; Tsurikisawa, N, 2010) |
"3% w/v (weight of solute per volume of solution) monoethanolamine (MEA) into his lungs, causing asthma-like symptoms." | 3.75 | Effects of inhaled monoethanolamine on bronchoconstriction. ( Hayashi, I; Ide, A; Kamijo, Y; Majima, M; Soma, K; Yoshimura, K, 2009) |
"This study was designed to examine the role of histamine in goblet cell hyperplasia using histamine-deficient mice (Hdc-/- mice) with allergic airway inflammation." | 3.75 | Enhanced goblet cell hyperplasia in HDC knockout mice with allergic airway inflammation. ( Inoue, H; Ito, H; Kobayashi, H; Maesawa, C; Mouri, T; Nakadate, T; Nakamura, Y; Ohtsu, H; Piao, HM; Sawai, T; Shikanai, T; Yamauchi, K, 2009) |
"This study aimed to investigate the effect of piperine on airway hyperresponsiveness, pulmonary eosinophilic infiltration, various immune cell phenotypes, Th2 cytokine production, immunoglobulin E and histamine production in a murine model of asthma." | 3.75 | Piperine inhibits eosinophil infiltration and airway hyperresponsiveness by suppressing T cell activity and Th2 cytokine production in the ovalbumin-induced asthma model. ( Kim, SH; Lee, YC, 2009) |
" No previously confirmed formal diagnosis of occupational asthma (OA) caused by hydroxylamine has been made." | 3.75 | Occupational asthma and the paper recycling industry. ( Francis, H; Hoyle, J; Niven, R; Tran, S, 2009) |
" Antiasthmatic actions in guinea pigs were observed by histamine and acetylcholine ultrasonic atomization test, involved isolated guinea pig tracheal smoth muscle experiment and anaphylactic shock of guinea pigs." | 3.75 | [Study on the antitussive and antiasthmatic effects of Radix Fici Hirtae]. ( Huang, SC; Lai, P; Liu, LF; Lu, DD; Tang, LH; Wang, Y; Ye, MR; Zhou, TN, 2009) |
" EXMO produced an increase in the Preconvulsion Dyspnea time induced by histamine and acetylcholine aerosol, a significant reduction in the elevated eosinophil and monocyte counts in the Broncho-Alveolar Lavage fluid of sensitized guinea pigs, reduction in the paw edema volume as compared to the control rats, and decrease in the elevated histamine release from the sensitized guinea pig lungs." | 3.75 | Investigation into the mechanism of anti-asthmatic action of Moringa oleifera. ( Goyal, BR; Goyal, RK; Mehta, AA, 2009) |
"Effects of quercetin inhalation on immediate (IAR), late-phase (LAR) and late late-phase (LLAR) asthmatic responses by exposure to aerosolized-ovalbumin (AOA) (2w/v% in saline, inhalation for 3 min) were studied in conscious guinea-pigs sensitized with AOA." | 3.74 | Quercetin inhalation inhibits the asthmatic responses by exposure to aerosolized-ovalbumin in conscious guinea-pigs. ( Choi, HH; Kim, CJ; Lee, JY; Moon, H; Moon, HJ; Sim, SS, 2008) |
" The aim of the present study was to evaluate the utility of coughing induced by the hypertonic histamine challenge in the differential diagnosis of asthma in a clinically relevant patient population." | 3.74 | Utility of cough response during hypertonic histamine challenge in diagnosing asthma. ( Kiviniemi, V; Koistinen, T; Kontra, KM; Koskela, HO; Magga, J; Peuhkurinen, K; Purokivi, M, 2008) |
" Further in vivo studies also displayed that hignamine could protect experimental asthma model induced by histamine in guinea pigs to prolong the latent periods of asthma." | 3.74 | Identification of higenamine in Radix Aconiti Lateralis Preparata as a beta2-adrenergic receptor agonist1. ( Bai, G; Liu, Z; Shi, Q; Yang, Y; Zhang, Q; Zhu, YY, 2008) |
"To assess the prevalence of bronchial hyperresponsiveness (BHR) in a population of north Finland among subjects with no previous diagnosis of asthma or chronic bronchitis by using histamine and methacholine challenges." | 3.74 | Bronchial hyperresponsiveness in a population of north Finland with no previous diagnosis of asthma or chronic bronchitis assessed with histamine and methacholine tests. ( Juusela, M; Kotaniemi, J; Lundbäck, B; Poussa, T; Sovijärvi, A, 2008) |
" Patients with asthma (N=25) underwent a histamine provocation until a 20% fall in forced expiratory volume in 1s (FEV(1))." | 3.74 | Differentiation between the sensory and affective aspects of histamine-induced bronchoconstriction in asthma. ( De Peuter, S; Demedts, M; Lemaigre, V; Van den Bergh, O; Van Diest, I; Verleden, G, 2007) |
"We derived prediction equations for HDM challenges using PC(20) histamine or PC(20) methacholine and skin sensitivity data obtained from patients with mild to moderate persistent asthma and validated these equations in an independent asthma population." | 3.74 | Validated safety predictions of airway responses to house dust mite in asthma. ( de Kluijver, J; Diamant, Z; Grootendorst, DC; Ravensberg, AJ; Ricciardolo, FL; Sterk, PJ; van Rensen, EL, 2007) |
"In 142 asthmatics without airway obstruction, bronchoconstriction was induced by inhalation of 1% histamine aerosol." | 3.74 | Area under the maximum expiratory flow-volume curve--a sensitive parameter in the evaluation of airway patency. ( Chalupová, J; Hladíková, M; Svobodová, T; Vávrová, V; Zapletal, A, 2008) |
"Gel contraction to histamine was examined in floating gels containing cultured ASM cells from subjects with and without asthma following overnight incubation while unattached (method 1) or attached (method 2) to casting plates." | 3.74 | Comparison of gel contraction mediated by airway smooth muscle cells from patients with and without asthma. ( Black, JL; Burgess, JK; Matsumoto, H; McParland, BE; Moir, LM; Oliver, BG; Roth, M, 2007) |
"To explore the use of oscillometry as a measure of airway responsiveness, 69 asthmatic children underwent histamine and methacholine bronchoprovocation using dosimeter-MedicAid (Jaeger Co." | 3.74 | The use of oscillometry as a measure of airway responsiveness in asthmatic children after histamine and methacholine bronchoprovocation with dosimeter-MedicAid and DeVilbiss nebulizers. ( Kopriva, F; Látalová, M; Plocová, A; Radová, L; Slezáková, L; Smatanová, D; Szotkowská, J; Zápalka, M; Závodská, J, 2007) |
"The purpose of the present study was to determine the effects of acetaldehyde on airway smooth muscle constriction and inflammation." | 3.74 | Effects of acetaldehyde on human airway constriction and inflammation. ( Fukushima, C; Kohno, S; Matsuse, H; Sadahiro, A; Shimoda, T, 2007) |
"One-hundred-and-sixty-eight consecutive adult asthma patients or volunteers underwent bronchoprovocation tests to both histamine and methacholine after determining their blood eosinophil counts, serum total IgE levels and skin test reactivity to 10 common aeroallergens." | 3.74 | Airways are more reactive to histamine than to methacholine in patients with mild airway hyperresponsiveness, regardless of atopy. ( Cho, JY; Choi, IS; Chung, SW; Kim, DH; Lee, S; Lee, WJ; Lee, YC, 2007) |
"To determine whether oral administration of cyproheptadine or cetirizine blocks the action of serotonin and histamine, respectively, and results in diminished eosinophilic airway inflammation in cats with experimentally induced asthma." | 3.74 | Effects of cyproheptadine and cetirizine on eosinophilic airway inflammation in cats with experimentally induced asthma. ( Jiji, RD; McGee Turner, JB; Reinero, CR; Schooley, EK; Spinka, CM, 2007) |
"Although histamine is a central mediator in the immediate allergic reaction, its role in goblet cell hyperplasia in the airway of asthma is not completely understood." | 3.74 | Progress in allergy signal research on mast cells: the role of histamine in goblet cell hyperplasia in allergic airway inflammation - a study using the Hdc knockout mouse. ( Inoue, H; Ito, H; Kobayashi, H; Maesawa, C; Mouri, T; Nakadate, T; Nakamura, Y; Niisato, M; Ohtsu, H; Piao, HM; Sawai, T; Shikanai, T; Yamauchi, K, 2008) |
"The levels of leukotriene E4 (LTE4) increased significantly after the challenge tests, both in the asthmatics (median: 354 pg/mg pre-challenge vs." | 3.73 | Urinary inflammatory mediators and inhalation of hypertonic saline in children. ( Böttcher, MF; Bruhammar, M; Mai, XM; Nilsson, L; Zetterström, O, 2005) |
"The aims of this study were to investigate whether 5'-AMP can produce a LAR, airway hyper-reactivity (AHR) and cell influx to the lungs, in a sensitized guinea-pig model of asthma, and to compare with the profile of activity after ovalbumin (OVA) inhalation." | 3.73 | Early- and late-phase bronchoconstriction, airway hyper-reactivity and cell influx into the lungs, after 5'-adenosine monophosphate inhalation: comparison with ovalbumin. ( Johnson, FJ; Smith, N, 2005) |
"There is significant overlap in the responsiveness to direct airway challenges, such as the histamine challenge, between asthmatic and non-asthmatic subjects, which decreases their accuracy in the diagnosis of asthma." | 3.73 | Hypertonicity of the challenge solution may increase the diagnostic accuracy of histamine challenge. ( Kontra, KM; Koskela, HO; Purokivi, MK; Randell, JT, 2005) |
"We have investigated the mechanisms of action of luteolin, a flavone found in Perilla frutescens, a Chinese herbal medicine for treating asthma." | 3.73 | Mechanisms of relaxant action of luteolin in isolated guinea pig trachea. ( Chang, JP; Chen, TT; Ko, WC; Leu, IJ; Shih, CM, 2005) |
"Adenosine, an important signaling molecule in asthma, produces bronchoconstriction in asthmatics." | 3.73 | A novel A1 adenosine receptor antagonist, L-97-1 [3-[2-(4-aminophenyl)-ethyl]-8-benzyl-7-{2-ethyl-(2-hydroxy-ethyl)-amino]-ethyl}-1-propyl-3,7-dihydro-purine-2,6-dione], reduces allergic responses to house dust mite in an allergic rabbit model of asthma. ( Batra, VK; Borron, P; Mustafa, SJ; Nadeem, A; Obiefuna, PC; Wilson, CN, 2005) |
"Among the 281 nonasthmatic participants studied, 58 (22%) had AHR to histamine, 33 (12%) had EIB, and 82 (29%) had AHR to histamine and/or EIB." | 3.73 | Outcome in adulthood of asymptomatic airway hyperresponsiveness to histamine and exercise-induced bronchospasm in childhood. ( Backer, V; Nepper-Christensen, SC; Porsbjerg, C; Ulrik, CS; von Linstow, ML, 2005) |
"Airway responsiveness to histamine, diurnal peak-flow variability, and bronchodilator reversibility cannot be used interchangeably as objective markers of asthma in epidemiologic studies." | 3.73 | Recognition of asthma in adolescents and young adults: which objective measure is best? ( Backer, V; Postma, DS; Ulrik, CS, 2005) |
"To investigate the role of histamine in airway remodeling, 50 healthy guinea pigs were divided into 5 groups: control group: nebulized inhalation of distilled water for 8 weeks; asthma model group: nebulized inhalation of ovalbumin (OVA) for 8 weeks after sensitization; continued asthma model group: nebulized inhalation of OVA for 14 weeks after sensitization; histamine group: nebulized inhalation of OVA for 14 weeks after sensitization and histamine was added in the last 6 weeks; antagonist group: nebulized inhalation of OVA for 14 weeks after sensitization and histamine receptor antagonists were added in the last 6 weeks." | 3.73 | Role of histamine in airway remodeling of asthmatic guinea pig. ( Chen, BS; Chen, QL; Liu, SY; Wang, XH; Ye, SQ; Yu, SB, 2005) |
"We investigated the effects of the neuropeptide met-enkephalin on histamine-induced bronhoconstriction in an experimental model of asthma." | 3.73 | Met-enkephalin effects on histamine-induced bronchoconstriction in guinea pigs. ( Curković, T; Gotovac, N; Konjevoda, P; Stambuk, N; Tjesić-Drinković, D; Votava-Raić, A, 2005) |
"To investigate whether the perception of dyspnea during histamine-induced bronchoconstriction might be used to identify patients with asthma who sense dyspnea poorly during exacerbation." | 3.73 | Perception of dyspnea during exacerbation and histamine-related bronchoconstriction in patients with asthma. ( Altunkaya, V; Bulcun, E; Ekici, A; Ekici, M; Kara, T; Karlidag, A; Keles, H, 2006) |
" Previously, it is reported that a high dose of L-97-1, a water-soluble, small molecule adenosine A(1) receptor antagonist, blocks early and late allergic responses, and bronchial hyper-responsiveness to histamine in a hyper-responsive rabbit model of allergic asthma." | 3.73 | Adenosine A1 receptor antagonist versus montelukast on airway reactivity and inflammation. ( Mustafa, SJ; Nadeem, A; Obiefuna, PC; Wilson, CN, 2006) |
" Bronchial asthma model induced by histamine-acetylcholine in guinea pigs was used to observe the antiasthmatic effects." | 3.73 | [Experimental studies on antitussive, expectorant and antiasthmatic effects of extract from Citrus grandis var. tomentosa]. ( Li, PB; Ma, Y; Su, WW; Wang, YG, 2006) |
"The aim of this study was to evaluate the influence of pretreatment with the phosphodiesterase-4 inhibitor rolipram on pulmonary resistance, influx of inflammatory cells, and histamine concentration in bronchoalveolar lavage fluid (BALF) during an experimental asthmatic reaction induced in ovalbumin (OA)-sensitized guinea pigs, challenged with OA inhalation." | 3.73 | Effects of the phosphodiestrase-4 inhibitor rolipram on lung resistance and inflammatory reaction in experimental asthma. ( Chazan, R; Glapiński, J; Grubek-Jaworska, H; Hoser, G; Nejman-Gryz, P, 2006) |
"In our model of asthma, guinea pigs were made sensitive with ovalbumine (OVA), a protein extracted from the white of egg, and provoked in a way repeated with aerosol challenge of OVA for the group OVA (1 challenge a day during six days)." | 3.73 | [Study of cellularity in bronchoalveolar fluid and bronchial reactivity to histamine in a model of asthma in guinea pig]. ( Aubier, M; Boczkowski, J; Lanone, S; Ouksel, H; Pretrolani, M; Samb, A, 2006) |
"Histamine has a variety of airway actions and is considered to be an important mediator in asthma." | 3.72 | Disruption of L-histidine decarboxylase reduces airway eosinophilia but not hyperresponsiveness. ( Hattori, T; Ichinose, M; Ishigaki-Suzuki, S; Koarai, A; Kuramasu, A; Makabe-Kobayashi, Y; Ohtsu, H; Sakurai, E; Shirato, K; Sugiura, H; Watanabe, T; Yamagata, S, 2003) |
"To study the presence of a sibling effect on markers of atopy (serum total IgE, specific IgE, skin tests) and asthma (bronchial hyper-responsiveness to histamine) in families ascertained through a parent with asthma." | 3.72 | Sibling effect on atopy in children of patients with asthma. ( Bleecker, ER; Jansen, DF; Koppelman, GH; Meyers, DA; Postma, DS; Schouten, JP; van der Heide, S, 2003) |
" We studied 153 asthmatics in stable condition, using a Borg scale to measure dyspnea perceived during a histamine bronchial challenge test." | 3.72 | [Asthma patients' perception of dyspnea during acute bronchoconstriction]. ( Belloch, A; de Diego, A; Martínez-Francés, ME; Martínez-Moragón, E; Perpiñá, M, 2003) |
"To investigate the pathogenic mechanism of late asthmatic response in comparison to early asthmatic response, changes of serum neutrophil chemotactic activity (NCA) using the Boyden chamber method and histamine level using the automated fluorometric analyzer were observed in 13 aspirin (ASA)-sensitive asthma subjects (group I: 7 early responders and group II: 6 dual responders) during lysine aspirin bronchoprovocation test (L-ASA BPT)." | 3.72 | Enhanced serum neutrophil chemotactic activity was noted in both early and late asthmatic responses during lysine-aspirin bronchoprovocation test in ASA-sensitive asthmatic patients. ( Kim, SS; Lee, SK; Lee, YM; Nahm, DH; Park, HS; Yoon, HJ, 2003) |
" The sensitivity and specificity of the tests, based on this response, were 82% and 65%, respectively, for the histamine challenge; 20% and 94%, respectively, for the mannitol challenge; 27% and 77%, respectively, for the NO measurement; 82% and 100%, respectively, for the bovine-specific serum IgE measurement; and 100% and 50%, respectively, for the SPT." | 3.72 | Inhalation challenge with bovine dander allergens: who needs it? ( Chan, HK; Koskela, H; Taivainen, A; Tukiainen, H, 2003) |
"Histamine is an important mediator released from activated mast cells provoked by allergen and has a substantial role in the pathophysiology of asthma." | 3.72 | Histamine deficiency in gene-targeted mice strongly reduces antigen-induced airway hyper-responsiveness, eosinophilia and allergen-specific IgE. ( Appel, J; Buzás, E; Falus, A; Keszei, M; Komlósi, Z; Kozma, GT; Losonczy, G; Magyar, P; Pállinger, E; Szabó, T; Szalai, C, 2003) |
"The aim of this study was to establish a conscious guinea-pig model with these essential features of asthma and to correlate these with bronchoalveolar lavage fluid (BALF) histamine and nitric oxide (NO) levels." | 3.72 | Early and late bronchoconstrictions, airway hyper-reactivity, leucocyte influx and lung histamine and nitric oxide after inhaled antigen: effects of dexamethasone and rolipram. ( Broadley, KJ; Toward, TJ, 2004) |
"The study objectives were to analyze the changes in exhaled carbon monoxide (COex) induced by histamine provocation challenge in asthmatic patients and to evaluate the relationship between COex and airway sensitivity and reactivity." | 3.72 | Relationship between exhaled carbon monoxide and airway hyperresponsiveness in asthmatic patients. ( García-Río, F; Pino, JM; Prados, C; Ramirez, M; Villamor, J; Viñas, A, 2004) |
"Because histamine receptor type I blockade attenuates allergic asthma, we asked whether complete neutralization of histamine by an arthropod-derived, high affinity histamine-binding protein (EV131) would prevent allergic asthma." | 3.72 | Arthropod-derived histamine-binding protein prevents murine allergic asthma. ( Couillin, I; Jacobs, M; Lefort, J; Maillet, I; Moser, R; Nuttall, PA; Paesen, GC; Ryffel, B; Vargaftig, BB; Weston-Davies, W, 2004) |
"Coupling seratrodast (SD), an antiasthmatic drug, with several different types of NO donors including oxatriazoles, N-hydroxyguanidines and furoxans; evaluating the antiasthmatic effects of coupled compounds by determining their inhibitory activity of guinea pig asthma induced by acetylcholine and histamine; and assessing NO releasing ability." | 3.72 | [Design, synthesis and antiasthmatic activities of NO-donating seratrodast derivatives]. ( Feng, XC; Ji, H; Qiu, SG; Zhang, YH; Zhang, ZG, 2004) |
"Bronchial responsiveness (BR) to histamine or methacholin is a common finding in adult non-asthmatic patients with allergic rhinitis." | 3.71 | Comparison of bronchial responsiveness to histamine in asthma, allergic rhinitis and allergic sensitization at the age of 7 years. ( Lau, S; Nickel, R; Niggemann, B; Sommerfeld, C; Wahn, U, 2002) |
"To clarify the contribution of stress to classical conditioning-associated asthmatic responses, the effect of fasting stress on conditioned histamine release was investigated in a guinea pig model of asthma." | 3.71 | Fasting stress exacerbates classical conditioned histamine release in guinea pigs. ( Endo, Y; Irie, M; Nagata, S, 2002) |
" In the present study, the roles of nitric oxide (NO) and superoxide anions (O2(-)) in allergen-induced airway hyperreactivity (AHR) after the late asthmatic reaction (LAR) were investigated ex vivo, by examining the effects of the NO synthase inhibitor N(omega)-nitro-L-arginine methyl ester (L-NAME) and superoxide dismutase (SOD) on the responsiveness to methacholine of isolated perfused guinea-pig tracheae from unchallenged (control) animals and from animals 24 h after ovalbumin challenge." | 3.71 | Role of nitric oxide and superoxide in allergen-induced airway hyperreactivity after the late asthmatic reaction in guinea-pigs. ( de Boer, J; Flendrig, L; Koopal, M; Meurs, H; Zaagsma, J, 2001) |
"The ovalbumin (OVA)-sensitized guinea pig is often used as an animal model of asthma and airway hyperreactivity." | 3.71 | Enhanced expression of mucin genes in a guinea pig model of allergic asthma. ( Adler, KB; Chorley, B; Fine, J; Greenfeder, S; Li, Y; Martin, LD; Minnicozzi, M; Pettersen, CA, 2001) |
"Asthmatic guinea pig models were established, after guinea pigs inhaled ovalbumin and dexamethasone, the thickness of airway wall was determined by contour tracing, using a digitizing pad and microcomputer." | 3.71 | [The role of dexamethasone on airway wall remodeling]. ( Di, X; Li, S; Qi, H, 2001) |
" (2) The incubation period of asthma induced by histamine and acetylcholine (ACh) in guinea pig were measured before and after beta-estradiol (1 mg/kg) were given intramuscularly." | 3.71 | Inhibition of beta-estradiol on trachea smooth muscle contraction in vitro and in vivo. ( Li, HF; Pang, JJ; Qu, SY; Xu, XB; Zhang, XY; Zheng, TZ, 2002) |
"Histamine and serotonin are important inflammatory mediators in the pathophysiology of asthma, and asthmatic patients have higher plasma histamine and serotonin levels than nonasthmatic control subjects." | 3.71 | Histamine and serotonin stimulate eotaxin production by a human lung fibroblast cell line. ( Haniuda, M; Koyama, S; Numanami, H; Okubo, Y; Sato, E; Takashi, S; Tsukadaira, A; Ushiyama, T, 2002) |
" To determine directly, the histamine responsiveness of the smallest airways, eight normal and 11 asymptomatic asthmatic subjects were studied utilizing a wedged bronchoscope technique." | 3.70 | Direct assessment of small airways reactivity in human subjects. ( Bleecker, ER; Liu, MC; Permutt, S; Wagner, EM, 1998) |
"The aim of the study was to characterize the mechanism of formaldehyde (FM)-induced nasal and bronchial response in asthmatic subjects with suspected FM allergy." | 3.70 | Airway response to formaldehyde inhalation in asthmatic subjects with suspected respiratory formaldehyde sensitization. ( Górski, P; Krakowiak, A; Pazdrak, K; Ruta, U, 1998) |
"Occupational asthma due to western red cedar is associated with histamine release from basophils and mast cells on exposure to plicatic acid (PA), but the mechanisms underlying this response remain unclear." | 3.70 | Is tyrosine kinase activation involved in basophil histamine release in asthma due to western red cedar? ( Chan, H; Chan-Yeung, M; Frew, A; Salari, H, 1998) |
"High levels of histamine can be found in the airways of asthma patients." | 3.70 | Histamine affects interleukin-4, interleukin-5, and interferon-gamma production by human T cell clones from the airways and blood. ( Bast, A; Bruinier, B; Hol, BE; Jansen, HM; Krouwels, FH; Lutter, R; Out, TA, 1998) |
"Alcohol-induced asthma, a phenomenon characteristic of Asians, is due to differences in alcohol metabolism, particularly acetaldehyde metabolism." | 3.70 | Correlation between alcohol-induced asthma and acetaldehyde dehydrogenase-2 genotype. ( Asai, S; Harda, S; Kohno, S; Shimoda, T; Takao, A, 1998) |
"Eight allergic asthmatic subjects, six normal subjects, and six atopic nonasthmatic subjects were challenged with saline in the lingula and with serial concentrations of histamine (1 x 10(-7) to 5 x 10(-5) mol/L) in the right middle lobe followed by bronchoalveolar lavage (BAL) 15 minutes and 6 hours later." | 3.70 | Identification of IL-16 as the lymphocyte chemotactic activity in the bronchoalveolar lavage fluid of histamine-challenged asthmatic patients. ( Center, DM; Cruikshank, WW; Fine, GD; Lim, KG; Mashikian, MV; Saukkonen, JJ; Tarpy, RE, 1998) |
"The release of histamine and leukotriene C4 (LTC4) from bronchoalveolar lavage (BAL) cells and peripheral blood stimulated with Ca ionophore A23187 was compared between atopic and nonatopic asthma." | 3.70 | Different roles of histamine and leukotriene C4 in the airways between patients with atopic and nonatopic asthma. ( Ashida, K; Hosaki, Y; Mifune, T; Mitsunobu, F; Tanizaki, Y; Tsugeno, H; Yokota, S, 1998) |
" Diary cards were collected 2 weeks later and measurements of exhaled NO levels, FEV1 and histamine bronchial hyperreactivity (PC20 histamine) were undertaken." | 3.70 | Exhaled nitric oxide; relationship to clinicophysiological markers of asthma severity. ( al-Ali, MK; Eames, C; Howarth, PH, 1998) |
"Elevated histamine concentrations were found in children with wheeze regardless of the aetiology, whereas ECP was only elevated in those asthmatics with atopy." | 3.70 | Inflammatory mediators in bronchoalveolar lavage samples from children with and without asthma. ( Brown, V; Ennis, M; Fitch, PS; Heaney, LG; Schock, BC; Shields, MD; Stevenson, EC; Taylor, R; Turner, G, 1999) |
"We examined the inhibitory effects of azelastine hydrochloride, which inhibits histamine release and blocks H1 receptors, in alcohol-induced asthma." | 3.70 | Inhibitory effects of azelastine hydrochloride in alcohol-induced asthma. ( Asai, S; Kohno, S; Matsuse, H; Mitsuta, K; Obase, Y; Shimoda, T; Takao, A, 1999) |
"The mechanics of the chest wall was studied in seven asthmatic patients before and during histamine-induced bronchoconstriction (B)." | 3.70 | Chest wall hyperinflation during acute bronchoconstriction in asthma. ( Bertoli, F; Duranti, R; Filippelli, M; Gigliotti, F; Gorini, M; Iandelli, I; Mancini, M; Misuri, G; Scano, G, 1999) |
"Serum levels of leukotriene (LT) B(4), LTC(4), platelet- activating factor, histamine, IL-1beta, IL-4, IL-5, IL-6, and GM-CSF were measured at different time points, first just before or during menstruation when the peak expiratory flow rate (PEFR) began to decrease precipitously and second during the menstrual midcycle week (days 10-16) when the PEFR returned to baseline values in patients with PMA and in age-matched asthma patients without PMA at the same intervals." | 3.70 | Prevention of severe premenstrual asthma attacks by leukotriene receptor antagonist. ( Matsui, T; Nakasato, H; Ohrui, T; Sasaki, H; Sekizawa, K; Tamura, G; Yamaya, M, 1999) |
"Spirometry, peak expiratory flow (PEF) measurement, histamine challenge test, and sputum induction with hypertonic saline inhalation were performed in 70 asymptomatic patients with asthma who were treated with bronchodilators or an inhaled corticosteroid (beclomethasone dipropionate, 400-800 microg/day) or both for more than 2 months." | 3.70 | Correlation between respiratory function and airway inflammation in asthma. ( Adachi, M; Hashimoto, T; Kobayashi, H; Kohno, Y; Minoguchi, K; Miyamoto, M; Ueno, K; Wada, K, 1999) |
"An analysis was undertaken to determine the optimal cut-off separating an asthmatic from a normal response to a bronchial provocation challenge by exercise and the inhalation of methacholine or histamine in children and young adults." | 3.70 | Cut-off points defining normal and asthmatic bronchial reactivity to exercise and inhalation challenges in children and young adults. ( Avital, A; Bar-Yishay, E; Godfrey, S; Springer, C, 1999) |
"To characterize membrane-receptor peculiarities in adrenergic and histaminergic systems under model peroxide effect in bronchial asthma (BA)." | 3.70 | [Membrane-receptor disorders in adrenergic and histaminergic systems under peroxide exposure in bronchial asthma patients]. ( Ivanova, VV; Mineev, VN; Nesterovich, II, 2000) |
"Histamine is involved in the pathophysiology of asthma, and histamine N-methyltransferase (HNMT) plays the dominant role in histamine metabolism in human bronchial epithelium." | 3.70 | Histamine N-methyltransferase pharmacogenetics: association of a common functional polymorphism with asthma. ( Bernstein, JA; Galinsky, RE; Liggett, SB; Weinshilboum, RM; Yan, L, 2000) |
" Bronchial hyperreactivity (BHR) was evaluated with histamine challenge test and the results were compared with those of 20 normal subjects and 20 current asthmatic patients." | 3.70 | Bronchial sensitivity to histamine in former asthmatics: redevelopment of symptoms during a year of followup. ( López, JM; Tálamo, C; Velázquez, J, 2000) |
" The present study was carried out to determine how prednisolone modulates airway response to histamine, including recovery from induced bronchospasm in asthmatics." | 3.70 | Prednisolone hastens recovery from histamine-induced bronchospasm in asthmatics. ( Chhabra, SK; Gupta, M, 2000) |
"To explore the relationship between interleukin-8 (IL-8) and airway hyper-responsiveness (AHR) of asthma in guinea pigs." | 3.70 | The relationship between interleukin-8 and airway hyperresponsiveness in guinea pigs. ( Lu, K; Qi, H; Wang, W, 1999) |
" Acute changes in lung function were induced by inhaled histamine followed by terbutaline, in 12 asthmatics and 12 subjects with chronic obstructive pulmonary disease (COPD)." | 3.69 | Perception of dyspnoea during acute changes in lung function in patients with either asthma or COPD. ( de Maertelaer, V; Noseda, A; Prigogine, T; Schmerber, J; Yernault, JC, 1995) |
" Incubation of bronchial epithelial cells from patients with asymptomatic asthma with interleukin-1 or histamine, for 8 to 24 hours, resulted in increased expression of endothelin-1 messenger RNA and release of appreciable amounts of the peptide to the culture medium." | 3.69 | Constitutive expression of endothelin in bronchial epithelial cells of patients with symptomatic and asymptomatic asthma and modulation by histamine and interleukin-1. ( Ackerman, V; Bellini, A; Carpi, S; Marini, M; Mattoli, S; Vassalli, G, 1995) |
"To determine whether a mu opiate agonist can constrict the human airways, the dose of codeine (C) or histamine (H) producing a 40% decrease (PD40) in specific airway conductance (SGAW) was measured in 17 asthmatic and 14 normal subjects." | 3.69 | Codeine-induced bronchoconstriction and putative bronchial opiate receptors in asthmatic subjects. ( Popa, V, 1994) |
" To evaluate if dysfunction of the EA causes asthma-like symptoms, we assessed bronchial and EA responsiveness to inhaled histamine in 441 patients who presented with at least one of three key symptoms--cough, wheeze, dyspnoea--but had neither documented asthma nor bronchial obstruction." | 3.69 | Are asthma-like symptoms due to bronchial or extrathoracic airway dysfunction? ( Brussino, L; Bucca, C; Bugiani, M; De Rose, V; Rolla, G, 1995) |
"The tracheal sounds of 29 children aged 8-19 years with asthma were recorded during airways obstruction caused by histamine inhalation using a system for continuous respiratory telemetry and computer analysis." | 3.69 | Characteristics of wheeze during histamine-induced airways obstruction in children with asthma. ( Dooijes, EH; Everaerd, WA; Kolk, AM; Prins, PJ; Rietveld, S; Rijssenbeek-Nouwens, LH; Smit, F, 1995) |
"The aim of the study was to investigate the possibility that the scoring of breathlessness during histamine bronchial provocation testing might be used to identify asthmatic subjects who sense dyspnea poorly during spontaneous bronchoconstriction." | 3.69 | A comparison of breathlessness during spontaneous asthma and histamine-induced bronchoconstriction. ( Boudreau, D; Gray-Donald, K; Martin, JG; Styhler, A, 1995) |
"A new guinea pig model of allergic asthma was used to investigate the effects of low doses of the phosphodiesterase inhibitors, rolipram (phosphodiesterase IV selective), ORG 20241 (N-hydroxy-4-(3,4-dimethoxyphenyl)-thiazole-2-carboximidamide; dual phosphodiesterase III/IV inhibitor with some selectivity for the phosphodiesterase IV isoenzyme), and of theophylline (non-selective) on allergen-induced early and late phase asthmatic reactions, bronchial hyperreactivity to histamine inhalation, and airway inflammation." | 3.69 | Phosphodiesterase inhibitors reduce bronchial hyperreactivity and airway inflammation in unrestrained guinea pigs. ( Meurs, H; Olymulder, CG; Santing, RE; Van der Molen, K; Zaagsma, J, 1995) |
"A histamine bronchial provocation test was performed in 20 adult patients with a diagnosis of asthma or symptoms of cough and/or shortness of breath." | 3.69 | Analysis of tidal expiratory flow pattern in the assessment of histamine-induced bronchoconstriction. ( Lane, DJ; Madgwick, RG; Morris, MJ, 1995) |
" In the present study arterial and mixed venous (pulmonary arterial) levels of these variables were determined before and after histamine-induced bronchoconstriction in non-medicated asthmatic subjects." | 3.69 | Sympathoadrenal responses to bronchoconstriction in asthma: an invasive and kinetic study of plasma catecholamines. ( Bevegård, S; Carlens, P; Hjemdahl, P; Larsson, K, 1995) |
"In order to study changes in respiratory sounds associated with acute bronchoconstriction and -dilatation, breath sounds of 11 children with asthma (age range, 10-14 years) were recorded at the chest and at the trachea during histamine challenge test and after subsequent bronchodilatation." | 3.69 | Frequency distribution of breath sounds as an indicator of bronchoconstriction during histamine challenge test in asthmatic children. ( Malmberg, LP; Sorva, R; Sovijärvi, AR, 1994) |
"It was concluded that BHR, assessed with PC20 histamine, is probably involved in the progression of airway obstruction in asthma." | 3.69 | Does bronchial hyperresponsiveness precede or follow airway obstruction in asthma or COPD? ( Dompeling, E; Folgering, H; Molema, J; van Grunsven, PM; van Schayck, CP; van Weel, C, 1994) |
"Incremental exercise testing, spirometry and histamine provocation tests were performed at sea level before the PRP, on admission to the Dutch Asthma Centre, Davos, after 5 weeks of exercise training, at discharge from the Centre and 6 and 12 months after discharge at sea level." | 3.69 | Pulmonary rehabilitation at moderate altitude: a 1-year follow-up. ( Bijl, D; Folgering, HT; Speelberg, B, 1994) |
"We performed histamine inhalation challenge in 106 patients with chronic sinusitis, during disease exacerbation and after treatment with antimicrobials and nasal flunisolide (100 micrograms daily) for 2 weeks." | 3.69 | Extrathoracic and intrathoracic airway responsiveness in sinusitis. ( Bucca, C; Bugiani, M; Chiampo, F; D'Alberto, M; Magnano, M; Rolla, G; Scappaticci, E, 1995) |
" To assess the sensitivity of histamine test (HT) and exercise test (ET), 45 asthmatic patients (31 men, 14 women, ages 9-34) with normal resting pulmonary function test were studied." | 3.69 | [Comparative study of 2 diagnostic tests of aspecific bronchial hyperreactivity]. ( Arnedillo, A; de Lucas, P; García de Pedro, J; Monturiol, JM; Puente, L; Tatay, E, 1994) |
"We documented changes in airflow obstruction and airway responsiveness to histamine after a period of 5 +/- 1 y in 40 subjects with mild to moderate asthma, 14 men and 26 women, aged 20-68 y (mean: 43." | 3.69 | Five-year changes in airflow obstruction and airway responsiveness in mild to moderate asthma. ( Boulet, LP; Jobin, C; Milot, J; Turcotte, H, 1994) |
" In conscious, permanently instrumented, unrestrained, ovalbumin-sensitized guinea-pigs the development of allergen-induced bronchial hyperreactivity to histamine- and methacholine-inhalation was investigated after the early as well as after the late asthmatic response." | 3.69 | Contribution of a cholinergic reflex mechanism to allergen-induced bronchial hyperreactivity in permanently instrumented, unrestrained guinea-pigs. ( Meurs, H; Olymulder, CG; Pasman, Y; Roffel, AF; Santing, RE; Zaagsma, J, 1995) |
"The effect of a new anti-asthmatic drug, TYB-2285 (3,5-bis(acetoxyacetylamino)-4-chlorobenzonitrile), was investigated in ovalbumin-sensitized guinea-pigs." | 3.69 | The effect of TYB-2285 on dual phase bronchoconstriction and airway hypersensitivity in guinea-pigs actively sensitized with ovalbumin. ( Muraki, M; Nagasaka, Y; Nakajima, S; Sugihara, R; Tohda, Y, 1994) |
"To determine whether the measurement of specific markers of inflammatory cells in peripheral blood might be used to detect the inflammatory activity in the airways in asthma induced by toluene diisocyanate (TDI), we measured the levels of eosinophil cationic protein (ECP), histamine and tryptase in peripheral blood before and during inhalation challenge with TDI or methacholine in two groups of subjects who exhibited or did not exhibit an asthmatic reaction after exposure to toluene diisocyanate in the laboratory." | 3.69 | Eosinophil cationic protein (ECP), histamine and tryptase in peripheral blood before and during inhalation challenge with toluene diisocyanate (TDI) in sensitized subjects. ( Borghesan, F; Calcagni, P; Fabbri, LM; Faggian, D; Maestrelli, P; Mapp, CE; Plebani, M; Saetta, M, 1994) |
"Serum ECP was measured in a double-blind study in relation to spirometry, flow-volume curves, and histamine PC20 (30-s tidal breathing method, normal value > 32 mg ml-1) in 20 chronic asthmatic patients (five male), mean age 48." | 3.69 | Serum eosinophil cationic protein (ECP) in chronic asthma. Relationship to spirometry, flow-volume curves, PC20, and exacerbations. ( Hensgens, HE; Hermans, J; Wever, AM; Wever-Hess, J, 1994) |
"The relationship among allergen-induced early asthmatic reactions (EARs) and late asthmatic reactions (LARs), early (between EAR and LAR) and late (after LAR) changes in bronchial reactivity to histamine and infiltration of inflammatory cells into the airways were investigated with a new model of chronically instrumented, unrestrained, and ovalbumin-sensitized guinea pigs." | 3.69 | Relationships among allergen-induced early and late phase airway obstructions, bronchial hyperreactivity, and inflammation in conscious, unrestrained guinea pigs. ( Meurs, H; Olymulder, CG; Santing, RE; Zaagsma, J, 1994) |
"Our objective was to examine the changes in regional ventilation during histamine-induced bronchoconstriction in stable asthma." | 3.69 | Changes in regional ventilation during histamine bronchial challenge in stable asthma. ( Flenley, DC; Ip, M; Kirby, T; Wathen, CG; Whyte, KF, 1994) |
"In asthmatic patients methacholine or histamine challenge may result in more rapid and shallow breathing." | 3.69 | Histamine induced changes in breathing pattern may precede bronchoconstriction in selected patients with bronchial asthma. ( Duranti, R; Fanelli, A; Gigliotti, F; Gorini, M; Scano, G; Spinelli, A, 1994) |
" To evaluate the relationship of circadian patterns in epinephrine and cortisol to nighttime airflow obstruction, 10 young adult asthma patients (ages 19 to 25 yr) were admitted to a hospital clinical research unit for a 3-day study during which plasma concentrations of epinephrine, cortisol, and histamine were determined along with white blood cell and eosinophil counts every 6 h (1600, 2200, 0400, and 1000 h)." | 3.69 | Relationship of plasma epinephrine and circulating eosinophils to nocturnal asthma. ( Bates, ME; Busse, W; Calhoun, W; Clayton, M; Geiger, K; Jarjour, N; Schrader, L; Schultz, T; Sedgwick, J; Swenson, C, 1994) |
"We investigated whether an exercise challenge protocol is suitable for measuring bronchial responsiveness in epidemiological studies of asthma in children, and determined its comparability with histamine challenge." | 3.69 | An exercise challenge protocol for epidemiological studies of asthma in children: comparison with histamine challenge. ( Anderson, SD; Haby, MM; Mellis, CM; Peat, JK; Toelle, BG; Woolcock, AJ, 1994) |
"The objective of this study was to determine whether exposure to ozone causes inflammatory or functional changes in the upper or lower airways of asthmatic and nonasthmatic individuals." | 3.69 | Inflammatory effects of ozone in the upper airways of subjects with asthma. ( Henderson, WR; Koenig, JQ; Luchtel, DL; McBride, DE; Williams, PV, 1994) |
"Histamine challenge testing is used to measure airway responsiveness in asthma." | 3.69 | Effect of magnitude of airway responsiveness and therapy with inhaled corticosteroid on histamine tachyphylaxis in asthma. ( Manning, PJ; O'Byrne, PM; Strban, M; Watson, RM, 1994) |
" Selected compounds have also been examined for their activities in inhibiting histamine-induced bronchospasm in anaesthetized guinea pigs." | 3.69 | Selective type IV phosphodiesterase inhibitors as antiasthmatic agents. The syntheses and biological activities of 3-(cyclopentyloxy)-4-methoxybenzamides and analogues. ( Ashton, MJ; Cook, DC; Fenton, G; Karlsson, JA; Palfreyman, MN; Raeburn, D; Ratcliffe, AJ; Souness, JE; Thurairatnam, S; Vicker, N, 1994) |
"In a new model using conscious, unrestrained and ovalbumin-sensitized guinea pigs, we investigated the effects of the selective histamine H1 receptor antagonist, mepyramine, on the development of allergen-induced early and late asthmatic reactions, bronchial hyperreactivity and airway inflammation, having each animal as its own control." | 3.69 | Role of histamine in allergen-induced asthmatic reactions, bronchial hyperreactivity and inflammation in unrestrained guinea pigs. ( Meurs, H; Olymulder, CG; Santing, RE; Schraa, EO; Wachters, A; Zaagsma, J, 1994) |
"Air-flow standardized breath sounds were recorded at the chest and at the trachea during histamine challenge test and after subsequent bronchodilation in 12 asthmatics and 6 healthy controls for spectral analysis, to be compared with simultaneous changes in spirometric variables." | 3.69 | Changes in frequency spectra of breath sounds during histamine challenge test in adult asthmatics and healthy control subjects. ( Haahtela, T; Katila, T; Malmberg, LP; Paajanen, E; Piirilä, P; Sovijärvi, AR, 1994) |
"To elucidate the mechanism of development of asthma, we tried to develop a model which elicited a late asthmatic response by a combination of systemic and inhaled sensitization with ovalbumin in guinea pigs." | 3.69 | Relationship between airway eosinophilia and airway hyperresponsiveness in a late asthmatic model of guinea pigs. ( Itoh, K; Mukaiyama, O; Satoh, Y; Takahashi, E; Yamaguchi, T, 1996) |
"The relationship between eosinophil count and pulmonary function (FEV1), respiratory symptoms, bronchial responsiveness to histamine and diurnal variation in peak expiratory flow rate (PEF) was studied in 70 subjects with bronchial asthma, of whom 24 had intrinsic and 46 extrinsic asthma." | 3.69 | Peripheral eosinophil counts as a marker of disease activity in intrinsic and extrinsic asthma. ( Ulrik, CS, 1995) |
"An oral ethanol challenge test, a leukocyte histamine release test, and an ELISA for detection of IgE specific to acetaldehyde-human serum albumin conjugate were carried out in 42 adults with bronchial asthma and nine healthy adults." | 3.69 | Investigation of the mechanism of alcohol-induced bronchial asthma. ( Asai, S; Fujiwara, C; Hara, K; Kohno, S; Matsuse, H; Sakai, H; Shimoda, T; Takao, A; Watanabe, T, 1996) |
"The influence of the breathing pattern on transcutaneous blood gases was evaluated in 18 boys and 8 girls 7-18 years of age, with bronchial asthma, during bronchial provocation with histamine-HCl." | 3.69 | Influence of breathing pattern on transcutaneous oxygen and carbon dioxide tension during histamine provocation in children with bronchial asthma. ( Bjure, J; Engström, I; Holmgren, D; Sixt, R; Sten, G, 1996) |
"We investigated the relation between IgE reactive with histamine-releasing factor (HRF) and clinical status in patients with asthma or rhinitis." | 3.69 | Reactivity to IgE-dependent histamine-releasing activity in asthma or rhinitis. ( Aalbers, M; Aalberse, RC; Jansen, HM; Knol, EF; Pasmans, SG; van der Veen, MJ; van der Zee, JS, 1996) |
"There was no relationship between the bronchial responsiveness to histamine and acetic acid cough threshold in these patients." | 3.69 | Relationship between the acid-induced cough response and airway responsiveness and obstruction in children with asthma. ( Mochizuki, H; Morikawa, A; Shimizu, T; Tokuyama, K, 1996) |
"The mean venous plasma histamine of 14 patients with eosinophilia was 18." | 3.69 | Plasma histamine in patients with tropical disorders and acute asthma who exhibit eosinophilia. ( Bruce, C; Taylor, WH, 1996) |
"Eleven adult asthmatic subjects were challenged twice with metabisulphite, aspirin, monosodium glutamate, artificial food colours, sodium nitrite/ nitrate, 0." | 3.69 | Assessment of food chemical intolerance in adult asthmatic subjects. ( Hodge, L; Loblay, RL; Yan, KY, 1996) |
"Obtained case histories were used to assess the presence of asthma; pulmonary function, skin prick test reactivity, total serum IgE and bronchial responsiveness to inhaled histamine were measured using standard techniques." | 3.69 | Risk factors for development of asthma in children and adolescents: findings from a longitudinal population study. ( Backer, V; Dirksen, A; Hesse, B; Ulrik, CS, 1996) |
"We have shown that inhalation of lysine aspirin enhances leukotriene production in the lungs of patients with aspirin-induced asthma (AIA)." | 3.69 | Bronchial aspirin challenge causes specific eicosanoid response in aspirin-sensitive asthmatics. ( Dworski, R; Nizankowska, E; Oates, J; Sheller, J; Sladek, K; Soja, J; Szczeklik, A, 1996) |
"We studied the function of autoinhibitory muscarinic M2 receptors on vagal nerve endings in the airways of conscious, unrestrained, ovalbumin-sensitized guinea pigs after the early and late allergic reaction." | 3.69 | Dysfunctional muscarinic M2 autoreceptors in vagally induced bronchoconstriction of conscious guinea pigs after the early allergic reaction. ( Krikke, M; Roffel, AF; Teisman, AC; Ten Berge, RE; Zaagsma, J, 1996) |
"Susceptibility to voice reactions during a histamine provocation test was studied in 21 asthmatics and 21 healthy subjects." | 3.69 | Voice reactions to histamine inhalation in asthma. ( Leinonen, L; Poppius, H, 1997) |
"We evaluated the relationship between blood markers of mast-cell (plasma histamine and serum level of heat-stable neutrophil chemotactic activity [NCA]) and eosinophil (serum eosinophil cationic protein [ECP]) activation during early airway response (EAR) and late airway response (LAR) to allergen inhalation in 24 asthmatic subjects." | 3.69 | Blood markers of early and late airway responses to allergen in asthmatic subjects. Relationship with functional findings. ( Bacci, E; Bancalari, L; Carletti, A; Cianchetti, S; Dente, FL; Di Franco, A; Ferdeghini, M; Giannini, D; Paggiaro, PL; Prontera, C; Taccola, M; Vagaggini, B, 1997) |
"We have compared the bronchoalveolar lavage fluid (BAL) cellular composition and the BAL cell lysate histamine content (fluorometric assay) in 28 stable mild to moderate asthmatics (atopic n = 18 and intrinsic n = 10) and 11 control subjects." | 3.69 | Correlation between bronchoalveolar lavage (BAL) fluid cell lysate histamine content and BAL fluid eosinophil count in atopic and nonatopic asthmatics. ( Corhay, JL; Louis, R; Mendez, P; Poncelet, M; Radermecker, M; Van Tulder, L, 1997) |
"To investigate the mechanisms of airway hyperresponsiveness (AHR), we examined the time course for asthmatic responses (including immediate asthmatic response (IAR), late asthmatic response (LAR), and AHR), airway inflammation (including edema in the airway, accumulation of inflammatory cells in bronchoalveolar lavage fluid (BALF), and mediator release including histamine and thromboxane A2 (TXA2) in BALF after the repeated provocation of aeroantigen in sensitized guinea pigs." | 3.69 | Time course study for airway inflammation and responsiveness by repeated provocation of aeroantigen in guinea pigs. ( Kogame, A; Nagai, H; Takeda, H; Tanaka, H, 1997) |
"Bronchial responsiveness to inhaled histamine was measured in 100 patients (age range, 28 to 79 years), of whom 62 had intrinsic and 38 had extrinsic asthma." | 3.68 | Bronchial responsiveness to inhaled histamine in both adults with intrinsic and extrinsic asthma: the importance of prechallenge forced expiratory volume in 1 second. ( Ulrik, CS, 1993) |
"The local release of histamine is considered to be largely responsible for the early asthmatic response to inhaled allergen, although its contribution to the late response is less well-established." | 3.68 | Plasma and urinary histamine in allergen-induced early and late phase asthmatic responses. ( Finnerty, JP; Holgate, ST; Wood-Baker, R, 1993) |
"Histamine is a major mediator of the mast cells that are present between epithelial cells in asthma." | 3.68 | Activation by histamine of bronchial epithelial cells from nonasthmatic subjects. ( Bousquet, J; Campbell, AM; Chanez, P; Godard, P; Lacoste, P; Michel, FB; Vignola, AM, 1993) |
" Data showing an increase of serum levels of ECP mainly in subjects with sensitivity to perennial allergens and related to histamine bronchial reactivity are discussed in view of their practical impact in diagnosing and monitoring of allergic diseases and asthma." | 3.68 | Markers of eosinophilic inflammation in allergic diseases. ( Adriani, E; Bonini, S; Bussa, S; Magrini, L; Ronchetti, F; Rumi, C; Tomassini, M, 1993) |
"We wanted to determine whether the airway response to inhaled leukotriene C4 (LTC4) is similar to inhaled leukotriene E4 (LTE4) in aspirin-sensitive asthma and, therefore, determined airway responsiveness to histamine, LTC4 and LTE4 in seven aspirin-sensitive subjects and 13 control asthmatic subjects, who were tolerant of aspirin." | 3.68 | Airway responsiveness to leukotriene C4 (LTC4), leukotriene E4 (LTE4) and histamine in aspirin-sensitive asthmatic subjects. ( Christie, PE; Lee, TH; Schmitz-Schumann, M; Spur, BW, 1993) |
"To study whether improvement in bronchial responsiveness contributes to outgrowing of asthma, PC20-histamine was measured longitudinally in nine nonsteroid-dependent asthmatic children (six boys, three girls), aged 8." | 3.68 | Spontaneous improvement in bronchial responsiveness and its limit during preadolescence and early adolescence in children with controlled asthma. ( Kondo, S, 1993) |
"We wanted to investigate whether asthmatic subjects change their ventilatory pattern consistently when forced expiratory volume in one second (FEV1) has declined by at least 20% during bronchial histamine challenge, in order to assess whether respiratory pattern analysis can be used to monitor bronchial obstruction continuously." | 3.68 | Ventilatory pattern during bronchial histamine challenge in asthmatics. ( Gustafsson, PM; Strömberg, NO, 1993) |
"Histamine is an important mediator of allergic inflammation and bronchial hyperresponsiveness (BHR), a hallmark of asthma." | 3.68 | Plasma histamine and bronchial reactivity in allergic asthma. ( Bury, T; Corhay, JL; Louis, R; Radermecker, MF, 1993) |
"Interaction among mediators such as bradykinin (BK), histamine (H), and prostaglandin (PG) D2 may contribute to reduction in airway caliber in asthma." | 3.68 | Interactive effect of inhaled bradykinin with histamine and PGD2 in bronchial asthma. ( Church, MK; Gnanakumaran, G; Holgate, ST; Howarth, PH; Rajakulasingam, K, 1993) |
"We have studied the effects of histamine on the proliferation and the intracellular cyclic adenosine monophosphate (cAMP) levels of T-lymphocyte clones (TLC) generated from bronchoalveolar lavage fluid (BALF) or peripheral blood (PB) from healthy and asthmatic persons." | 3.68 | Heterogeneous effects of histamine on proliferation of lung- and blood-derived T-cell clones from healthy and asthmatic persons. ( Bast, A; Bruinier, B; Hol, BE; Jansen, HM; Krouwels, FH; Lutter, R; Out, TA; Wierenga, EA, 1993) |
"A rapid dosimetric method with controlled tidal breathing for histamine challenge was evaluated by assessment of its repeatability, by comparing to a present nondosimetric standard method, and by application to adult patients with recent asthma (n = 31), chronic asthma (n = 33), chronic cough (n = 71) or chronic rhinitis (n = 41) and to healthy controls (n = 31)." | 3.68 | A rapid dosimetric method with controlled tidal breathing for histamine challenge. Repeatability and distribution of bronchial reactivity in a clinical material. ( Malmberg, LP; Poppius, H; Reinikainen, K; Rytilä, P; Sovijärvi, AR, 1993) |
"Bronchial reactivity was assessed in 66 children with bronchial asthma (aged 8-15 years) by provocation with histamine-HCl during a symptom-free period." | 3.68 | Respiratory resistance and transcutaneous PO2 during histamine provocation in children with bronchial asthma. ( Aberg, N; Bjure, J; Engström, I; Holmgren, D; Sixt, R, 1993) |
"To investigate the possible role of mast cell or basophil histamine release in mediating platelet-activating factor (PAF) airway obstruction, we studied the effect of inhaled PAF (30 micrograms, single dose) on plasma histamine, bronchial caliber, and leukocyte and platelet counts in six patients with mild or moderate allergic asthma (mean age, 27 +/- 1." | 3.68 | No increase in plasma histamine during PAF-induced airway obstruction in allergic asthmatics. ( Bury, T; Corhay, JL; Louis, R; Radermecker, M, 1993) |
" The degree of voluntary activation during repeated attempted maximal quasi-static efforts was determined using the twitch interpolation technique in the absence of contractile fatigue under both control conditions and following bronchial challenge with histamine." | 3.68 | Reduced voluntary drive to breathe in asthmatic subjects. ( Allen, GM; Bass, S; Gandevia, SC; McKenzie, DK, 1993) |
"The effect of rolipram, an isozyme IV-selective inhibitor of cAMP-specific phosphodiesterase, was evaluated in a guinea pig eye model of tissue eosinophilia." | 3.68 | cAMP-specific phosphodiesterase inhibitor, rolipram, reduces eosinophil infiltration evoked by leukotrienes or by histamine in guinea pig conjunctiva. ( Newsholme, SJ; Schwartz, L, 1993) |
"We attempted to determine the relationship of nasal polyps to histamine (HA) metabolism." | 3.68 | Histamine metabolism in nasal polyps. ( Abe, Y; Fukui, H; Harada, T; Imamura, I; Irifune, M; Matsunaga, T; Ogino, S, 1993) |
"Improvement of asthmatic symptoms was shown to be closely associated with a decrease in bronchial hypersensitivity to histamine inhalation." | 3.68 | Bronchial hypersensitivity in asthmatics in long-term symptom-free state. ( Hoshino, K; Kawasaki, A; Kobayashi, M; Mizushima, Y; Oosaki, R, 1993) |
"The bisbenzylisoquinoline analogues, tetrandrine and berbamine, were investigated for their effects on guineapig airway microvascular leakage, an animal model of asthma and allergic inflammation." | 3.68 | Comparative effects of tetrandrine and berbamine on guineapig airway microvascular leakage induced by platelet-activating factor and other allergic mediators. ( Seow, WK; Thong, YH; Wong, CW, 1993) |
" It was completed by 211 adults and validated by comparison with a self reported history of asthma and with bronchial hyperresponsiveness to histamine." | 3.68 | Respiratory symptoms questionnaire for asthma epidemiology: validity and reproducibility. ( Farrer, N; Graneek, BJ; Newman Taylor, AJ; Sharp, L; Venables, KM, 1993) |
"The latent period of ovalbumin (Ova)-induced asthma in Ova-sensitized guinea pigs was shorter in the ovariectomized animals with sc estradiol (E2) 400 or 50 micrograms." | 3.68 | [Effect of estradiol on the course of ovalbumin sensitization in guinea pigs]. ( Wan, Y; Weng, SA, 1993) |
"The effect of antiallergic agents (DSCG) (disodium cromoglycate, ketotifen, and ibudilast) and beclomethasone dipropionate inhaler (BDI) on bronchial hyperresponsiveness to histamine inhalation was retrospectively assessed in 72 asthmatic patients with more than a year's duration of the disease." | 3.68 | Comparison of the effects on bronchial hyperresponsiveness of antiallergic agents and beclomethasone dipropionate in long-term bronchial asthma. A retrospective study. ( Hoshino, K; Kawasaki, A; Kobayashi, M; Mizushima, Y; Oosaki, R; Yano, S, 1993) |
"Recently, there has been an increasing interest in the involvement of adenosine as a mediator of allergic asthma." | 3.68 | Adenosine-induced bronchoconstriction in an allergic rabbit model: antagonism by theophylline aerosol. ( Ali, S; Metzger, WJ; Mustafa, SJ, 1992) |
"The effects of theophylline on allergen-induced airway obstruction and bronchial hyperresponsiveness were investigated in allergic rabbits." | 3.68 | Modification of allergen-induced airway obstruction and bronchial hyperresponsiveness in the allergic rabbit by theophylline aerosol. ( Ali, S; Metzger, WJ; Mustafa, SJ, 1992) |
"The influence of single and repeated LO (10 mg/day) doses on histamine-induced bronchoconstriction was studied in 11 patients with stabile bronchial asthma." | 3.68 | [Effect of loratadine (LO), a selective H1 antagonist, on histamine-induced bronchoconstriction]. ( Cieślewicz, G; Gondorowicz, K; Grzelewska-Rzymowska, I; Rozniecki, J; Wojciechowska, B, 1992) |
"The effect of two anticholinergic drugs, Ipratropium bromide, nonselective muscarinic receptor antagonist and Pirenzepine, a selective M1 receptor blocker on bronchospasm induced by metacholine and histamine was investigated." | 3.68 | [The effect of muscarinic receptor blockers on non-specific bronchial reactivity in patients with bronchial asthma]. ( Siergiejko, Z, 1992) |
" We assayed urinary LTE4 in 17 normal subjects, 31 subjects with asthma without aspirin sensitivity, and 10 aspirin-sensitive subjects." | 3.68 | Urinary leukotriene E4 in bronchial asthma. ( Christie, PE; Hawksworth, RJ; Lee, TH; Smith, CM; Thien, FC, 1992) |
" To investigate the role of mast cells and eosinophils in the pathogenesis of nocturnal asthma, the plasma methylhistamine concentration, serum eosinophil cationic protein level and peak expiratory flow rate were measured 2-hourly for 24 h in 10 patients with nocturnal asthma and in 10 healthy control subjects." | 3.68 | Circulating histamine and eosinophil cationic protein levels in nocturnal asthma. ( Church, MK; Douglas, NJ; Fitzpatrick, MF; Holgate, ST; Mackay, T; Tai, PC; Walters, C, 1992) |
"Described is a guinea pig model of allergic asthma, in which animals are sensitized by intraperitoneal injections of ovalbumin complexed with aluminum hydroxide to elicit an IgE response." | 3.68 | Induction by aerosol allergen of sustained and nonspecific IgE-mediated airway hyperreactivity in the guinea pig. ( DeLeo, JJ; Handley, DA; Havill, AM, 1992) |
"The effects of a newly synthesized pyridazinone derivative, NZ-107, 4-bromo-5-(3-ethoxy-4-methoxybenzylamino)-3(2H)-pyridazinone, and two well-known antiasthmatic drugs, amlexanox (orally active disodium cromoglycate-like drug) and disodium cromoglycate (DSCG) on antigen-, histamine- and leukotriene C4 (LTC4)-induced constriction of isolated human tracheal muscle, and histamine release from human lung tissues and leukocytes were investigated in vitro." | 3.68 | Effect of NZ-107, a newly synthesized pyridazinone derivative, on antigen-induced contraction of human bronchial strips and histamine release from human lung fragments or leukocytes. ( Daikoku, M; Iwama, T; Koda, A; Nagai, H; Suda, H; Yanagihara, Y, 1992) |
"Altogether 300 patients suffering from bronchial asthma were examined for serotonin metabolism, the kallikrein-kinin system and histamine." | 3.68 | [The role of serotonin, histamine and the kallikrein-kinin system in the pathogenesis of asphyxic attacks in bronchial asthma]. ( Fedoseev, GB; Goncharova, VA; Kachanova, TA; Razumovskaia, TL; Zhikharev, SS, 1992) |
"In order to clarify the role of leukotriene in the antigen-induced asthmatic response, we carried out mite-antigen, leukotriene D4 (LTD4) and histamine inhalation tests in 21 mite-sensitive atopic asthma patients, and investigated the relationship between the bronchial responsiveness to mite (PD20-Mite) and that to LTD4 and histamine (PD20-LTD4, PD20-Hist)." | 3.68 | [The role of bronchial responsiveness to leukotrienes in antigen-induced immediate and late asthmatic response]. ( Amagai, M; Fukuda, T; Makino, S; Motojima, S; Numao, T; Otsuka, T; Toda, M; Watanabe, S; Yamai, T, 1992) |
"We evaluated the levels of bradykinin, albumin, TAME-esterase activity, histamine, PGD2 and LTC4 in bronchoalveolar lavage fluid from asthmatics and from patients with pneumonia, sarcoidosis, fibrosis, and chronic bronchitis." | 3.68 | Bradykinin and other inflammatory mediators in BAL-fluid from patients with active pulmonary inflammation. ( Baumgarten, CR; Brunnee, T; Dorow, P; Henning, R; Kunkel, G; Lehmkuhl, B; Schilling, W, 1992) |
"Asthmatic subjects performed up to four series (on separate days) of 18 maximal static inspiratory efforts of 10 seconds' duration with 10 second rest intervals (50% duty cycle; total duration six minutes): at functional residual capacity (FRC) (control); after histamine induced bronchoconstriction, which decreased forced expiratory volume in one second (FEV1) to a mean of 55% (SD 11%) of the initial value; at a voluntarily increased lung volume (initial volume held at 140% control); and after inhalation of histamine at a voluntarily increased lung volume." | 3.68 | Inspiratory muscle strength and endurance during hyperinflation and histamine induced bronchoconstriction. ( Gandevia, SC; Gorman, RB; McKenzie, DK; Plassman, BL, 1992) |
"Two nurses who frequently examined patients with methacholine or histamine challenge tests developed increased airway responsiveness and symptoms of asthma." | 3.68 | Development of increased airway responsiveness in two nurses performing methacholine and histamine challenge tests. ( Lundgren, R; Norrman, E; Rosenhall, L; Söderberg, M, 1992) |
"The use of the histamine challenge test (HCT) for the diagnosis of asthma has so far been limited to older children who can perform spirometry consistently." | 3.68 | Histamine challenge in young children using computerized lung sounds analysis. ( Beck, R; Dickson, U; Mitchell, I; Montgomery, MD, 1992) |
"Forty asthmatic children aged 4 to 6 years performed histamine inhalation tests over 2 to 3 years." | 3.68 | Longitudinal study of bronchial hyperreactivity in preschool children with bronchial asthma. ( Adachi, Y; Adachi, YS; Igarashi, T; Kayahara, M; Matsuno, M; Murakami, G; Okada, T; Yoshizumi, A, 1992) |
"Prostaglandin D2 (PGD2) and thromboxane A2 (TXA2) have been suggested to play important roles in the pathogenesis of bronchial asthma." | 3.68 | [Bronchial hyperresponsiveness to histamine induced by intravenous administration of prostaglandin D2 (PGD2) in guinea pigs]. ( Kurosawa, M; Tsukagoshi, H, 1992) |
"The sensitivity and specificity of monitoring peak expiratory flow rates (PEFR) and bronchial responsiveness to the provocative concentration of histamine or methacholine (PC20) has been determined as compared to specific inhalation challenges in the diagnosis of occupational asthma." | 3.68 | Occupational asthma: validity of monitoring of peak expiratory flow rates and non-allergic bronchial responsiveness as compared to specific inhalation challenge. ( Boulet, LP; Cartier, A; Côté, J; L'Archevêque, J; Lagier, F; Malo, JL; Perrin, B, 1992) |
"The effect of a prior histamine challenge on the bronchodilator response to salbutamol after spontaneous recovery of FEV1 to 95% of the prechallenge level was studied in two groups of asthmatic children." | 3.68 | Assessment of bronchodilatation after spontaneous recovery from a histamine challenge in asthmatic children. ( Duiverman, EJ; Kerrebijn, KF; Merkus, PJ; Quanjer, PH; Rooda, HM; van Essen-Zandvliet, EE, 1992) |
" To investigate the role of platelet activating factor (PAF) in the immediate asthmatic response, we examined the bronchial reactivity to histamine after administration of PAF to guinea-pigs or antigen challenge to passively sensitized guinea-pigs." | 3.68 | Platelet-activating factor (PAF) plays an important role in the immediate asthmatic response in guinea-pig by augmenting the response to histamine. ( Imanishi, N; Morooka, S; Uchida, M, 1992) |
" Administration of erythromycin to asthmatic patients in a dosage of 600 mg/d for 10 weeks reduced the bronchial hyperresponsiveness measured by histamine inhalation test." | 3.68 | Effect of erythromycin on bronchial hyperresponsiveness in patients with bronchial asthma. ( Miyatake, H; Satake, T; Suzuki, K; Takagi, K; Taki, F, 1991) |
"The effect of antiallergic agents with no antihistamine activity on bronchial hypersensitivity to histamine inhalation was studied in 37 asthmatic patients." | 3.68 | Effect of antiallergic agents and bronchial hypersensitivity in short-term bronchial asthma. ( Hoshino, K; Kawasaki, A; Mizushima, Y; Yano, S, 1991) |
" ASA challenges were performed in 17 ASA-sensitive patients with asthma and rhinosinusitis, and tryptase and histamine levels were measured in their venous blood samples." | 3.68 | Tryptase and histamine release during aspirin-induced respiratory reactions. ( Bosso, JV; Schwartz, LB; Stevenson, DD, 1991) |
"The purpose of this investigation was to study factors of importance for the degree of bronchial responsiveness and, furthermore, to evaluate the sensitivity, specificity and predictive value of a bronchial challenge test with histamine for the diagnosis of asthma in 495 randomly selected children and adolescents, aged 7-16 yrs, from Copenhagen, Rigshospitalet." | 3.68 | Sensitivity and specificity of the histamine challenge test for the diagnosis of asthma in an unselected sample of children and adolescents. ( Bach-Mortensen, N; Backer, V; Dirksen, A; Groth, S; Hansen, KK; Laursen, EM; Wendelboe, D, 1991) |
"To determine the characteristics and reproducibility of circadian rhythms of airway responsiveness to histamine and methacholine and their relationship to airway tone in patients with mild asthma, we studied nine subjects with complaints of nighttime awakening due to dyspnea and/or cough at least once a week." | 3.68 | Circadian rhythm in airway responsiveness and airway tone in patients with mild asthma. ( Bonnet, R; Heitmann, U; Jörres, R; Magnussen, H, 1991) |
"A single oral dose of verapamil 80 mg was shown significantly to inhibit histamine-induced broncho-constriction in 8 out of 16 asthmatic subjects (maximum increase in PD20FEVHi 416%)." | 3.68 | Verapamil in the prophylaxis of bronchial asthma. Is the bronchoprotective effect related to the plasma level? ( Elsasser, S; Follath, F; Ha, HR; Imhof, E; Perruchoud, AP; Rosmus, B, 1991) |
"Thromboxane A2 (TXA2) has been suggested to play an important role in the pathogenesis of bronchial asthma." | 3.68 | [Bronchial hyperresponsiveness to histamine induced by intravenous administration of thromboxane A2 (TXA2) in guinea-pigs]. ( Kurosawa, M; Tsukagoshi, H, 1991) |
"Plasma histamine, cortisol, epinephrine, cyclic adenosine monophosphate (cAMP), and leukocyte beta-adrenergic receptors were measured in asthmatic patients with (n = 7) and without (n = 10) nocturnal asthma at 4 PM and 4 AM and compared with those of normal subjects (n = 10)." | 3.68 | Plasma histamine, epinephrine, cortisol, and leukocyte beta-adrenergic receptors in nocturnal asthma. ( Ando, R; Cicutto, LC; Hill, MR; Martin, RJ; Surs, W; Szefler, SJ, 1991) |
"To study the temporal relation between the peak of circadian variation of bronchial responsiveness and the trough of circadian variation of bronchial caliber, we performed seven inhalation challenges with histamine at 4-h intervals in six stable asthmatic children aged eight to ten years." | 3.68 | Priority of peak circadian variation of bronchial responsiveness to the trough of circadian variation of bronchial caliber in asthmatic children. ( Abe, K; Kondo, S, 1991) |
"Pretreatment to guinea pigs with sc isoprenaline (Iso) 10 micrograms/kg tid x 7 d reduced the effect of Iso on protecting histamine-induced asthma and decreased its pD2 values in relaxing isolated tracheal strip." | 3.68 | [Difference of tolerances to isoprenaline between tracheal and vascular smooth muscles and cardiac conduction system in guinea pigs]. ( Cao, YS; Sun, GL; Zhao, SJ, 1990) |
"Tracheal smooth muscle from seven cases of fatal asthma demonstrated an increased contractile response to histamine, acetylcholine, and electrical stimulation of intrinsic cholinergic nerves; impaired relaxation to isoproterenol, and possibly theophylline, was also evident (1)." | 3.68 | Abnormalities in airway smooth muscle in fatal asthma. A comparison between trachea and bronchus. ( Bai, TR, 1991) |
" We analyzed 126 dV/Vt ratios and compared them with spirometric and plethysmographic results measured in 24 healthy (14 males) and 60 asthmatic (41 males) children; 42 of them underwent measurements before and after bronchial challenge with histamine." | 3.68 | Analysis of expiratory pattern for monitoring bronchial obstruction in school-age children. ( Cutrera, R; Filtchev, SI; Haluszka, J; Merolla, R; Ronchetti, R; Willim, G, 1991) |
" Under controlled conditions in a climate chamber, 11 persons with bronchial hyperreactivity to histamine and bronchial asthma were exposed for 90 min to a mixture of organic solvents at levels of zero, 2." | 3.68 | Lung function and bronchial reactivity in asthmatics during exposure to volatile organic compounds. ( Dahl, R; Harving, H; Mølhave, L, 1991) |
"Tachyphylaxis to histamine was investigated in 16 children, aged 7-15 years, with mild asthma." | 3.68 | Repeated provocation tests in asthmatic children for testing tachyphylaxis to histamine. ( Gerritsen, J; Knol, K; Roorda, RJ; Schouten, JP; van Aalderen, WM, 1991) |
"We measured the concentration of inhaled histamine required to reduce the FEV1 by 20% (PC20) in seven asthmatic patients immediately following the inhalation of warm air (mean temperature +/- 1 SD, 21." | 3.68 | Effect of cold air on the bronchial response to inhaled histamine in patients with asthma. ( Cockcroft, DW; Dosman, JA; Hodgson, WC, 1991) |
"Bronchoalveolar lavage (BAL) fluid was evaluated for histamine and tryptase levels in 61 samples (46 samples from 24 atopic asthmatics, seven samples from seven patients with allergic rhinitis, and eight samples from eight normal volunteers)." | 3.68 | Elevated bronchoalveolar lavage fluid histamine levels in allergic asthmatics are associated with increased airway obstruction. ( Busse, WW; Calhoun, WJ; Jarjour, NN; Schwartz, LB, 1991) |
"A study was carried out to investigate whether an imbalance in the autonomic nervous system or release of histamine, or both, is responsible for the nocturnal increase in airflow obstruction in asthmatic children." | 3.68 | Nocturnal airflow obstruction, histamine, and the autonomic central nervous system in children with allergic asthma. ( Knol, K; Koëter, GH; Postma, DS; van Aalderen, WM, 1991) |
"Responsiveness to inhaled histamine and DL propranolol hydrochloride was measured in 31 adult asthmatics and compared with bronchoconstriction provoked by acute oral propranolol dosing (max 160 mg)." | 3.68 | Bronchoconstriction of the asthmatic airway by inhaled and ingested propranolol. ( Latimer, KM; Ruffin, RE, 1990) |
"Low levels of [3H]-dihydroergocryptine (DHE) (alpha adrenergic receptor) binding to peripheral blood mononuclear leukocytes from asthmatic subjects were significantly increased following incubation with histamine." | 3.68 | Effects of histamine on alpha adrenergic receptor expression on the lymphocytes of normal and asthmatic subjects. ( Easton, JG; Goldberg, BJ; Herman, FF; Kaplan, M; Lad, PM; Neidzin, H, 1990) |
"Airways responsiveness to leukotriene (LT) C4, LTD4, LTE4, histamine, and methacholine have been studied in eight asthmatic and six normal subjects." | 3.68 | Asthmatic airways have a disproportionate hyperresponsiveness to LTE4, as compared with normal airways, but not to LTC4, LTD4, methacholine, and histamine. ( Arm, JP; Crea, AE; Fong, CY; Hawksworth, RJ; Lee, TH; O'Hickey, SP; Spur, BW, 1990) |
"Bronchial hyperresponsiveness (BHR) to inhaled histamine has often been cited as the gold standard in asthma diagnosis, but recently this has been questioned." | 3.68 | The interrelationship among bronchial hyperresponsiveness, the diagnosis of asthma, and asthma symptoms. ( Asher, MI; Harrison, AC; Mitchell, EA; Pattemore, PK; Rea, HH; Stewart, AW, 1990) |
"To determine whether bronchoconstriction induced by sulfur dioxide can be predicted by the airway response to inhaled histamine, we exposed on two days 46 patients with asthma to air or 0." | 3.68 | Relationship between the airway response to inhaled sulfur dioxide, isocapnic hyperventilation, and histamine in asthmatic subjects. ( Jörres, R; Magnussen, H; von Nieding, G; Wagner, HM, 1990) |
"Four patients with asthma caused by occupational exposure to tetrachlorophthalic anhydride (TCPA) had dust-challenge tests that used eight different levels of TCPA exposure." | 3.68 | Exposure-response relationships in asthma caused by tetrachlorophthalic anhydride. ( Newman Taylor, AJ; Venables, KM, 1990) |
"The aim of this study was to compare the diagnostic value of common allergy tests with basophil histamine release in 124 children with symptoms of asthma." | 3.68 | Diagnostic value of a glass fibre-based histamine analysis for allergy testing in children. ( Nolte, H; Schiøtz, PO; Storm, K, 1990) |
" Bronchial responsiveness to histamine administered by tidal breathing was therefore compared with that produced with a dosimeter in 25 children with asthma aged 5-18 years." | 3.68 | Does the outcome of the tidal breathing and dosimeter methods of assessing bronchial responsiveness in children with asthma depend on age? ( Birnie, D; Hop, WC; Kerrebijn, KF; thoe Schwartzenberg, GW; van Essen-Zandvliet, EE, 1990) |
"Inspiratory breath sounds were recorded from the chest wall during histamine challenge in five subjects with mild asthma (baseline FEV1 greater than 60% of predicted normal)." | 3.68 | Variation of breath sound and airway caliber induced by histamine challenge. ( Aitken, S; Anderson, K; Carter, R; MacLeod, JE; Moran, F, 1990) |
"Histamine provocation challenges were performed in 60 patients with pulmonary sarcoidosis." | 3.68 | [Patients with sarcoidosis frequently have bronchial hyperreactivity]. ( Kanzow, G; Magnussen, H; Nowak, D, 1990) |
"This study was carried out to determine leukocyte phospholipase A2 (PLA2) activity and plasma lysophosphatidylcholine (LPC) levels in normal subjects and in patients with asthma and rhinitis and to examine their relationship to airway sensitivity to histamine." | 3.68 | Increased leukocyte phospholipase A2 activity and plasma lysophosphatidylcholine levels in asthma and rhinitis and their relationship to airway sensitivity to histamine. ( Agrawal, KP; Gangal, SV; Gaur, SN; Gupta, S; Mehta, D, 1990) |
"While some studies have clearly shown that tachyphylaxis occurs in asthmatic subjects when challenged consecutively with inhaled histamine, others were unable to demonstrate this phenomenon." | 3.68 | Lack of tachyphylaxis to histamine in both moderate and mild asthmatic subjects. ( Finnerty, JP; Holgate, ST; Polosa, R, 1990) |
"Although some studies have clearly demonstrated tachyphylaxis to inhaled histamine in subjects with asthma, other studies have not." | 3.68 | Tachyphylaxis to inhaled histamine in asthma: its significance and relationship to basal airway responsiveness. ( Finnerty, JP; Holgate, ST; Polosa, R, 1990) |
"Concomitant intradermal injection of salbutamol inhibits histamine-induced weal volume in the skin of atopic asthmatic subjects and the degree of this inhibition (index of beta-adrenergic effect in the skin) correlates with the bronchodilator effect of inhaled salbutamol in the same subjects (index of beta-adrenergic effect in the lung)." | 3.67 | Beta-adrenoceptor agonist responses in the skin and lungs of asthmatic subjects. ( Basran, GS; Morley, J; Paul, W, 1984) |
" To evaluate the role of alpha-adrenergic activity in the development of bronchoconstriction during airway cooling, we examined the effects of alpha-adrenergic blockade with phentolamine on bronchospasm induced by exercise and isocapnic cold air hyperventilation in 8 asthmatics." | 3.67 | Effect of alpha-adrenergic blockade on exercise-induced asthma and conditioned cold air. ( Bleecker, ER; Britt, EJ; Chahal, K; Mason, P; Permutt, S; Walden, SM, 1984) |
"The relationship of airway cooling during exercise to changes in airway caliber, plasma histamine levels, and circulating basophils was investigated in eight allergic asthmatic and eight normal subjects." | 3.67 | Exercise and isocapnic hyperventilation-induced bronchoconstriction in asthma: relevance of circulating basophils to measurements of plasma histamine. ( Church, MK; Holgate, ST; Howarth, PH; Pao, GJ, 1984) |
"Circulating concentrations of the mast cell-associated mediators, histamine and neutrophil chemotactic factor (NCF) of high molecular weight, were measured in atopic and nonatopic asthmatics after treadmill exercise." | 3.67 | Mediators in exercise-induced asthma. ( Cromwell, O; Iikura, Y; Kay, AB; Lee, TH; Nagakura, T; Papageorgiou, N, 1984) |
"In 16 asymptomatic asthmatics a functional study was carried out under controlled conditions during histamine bronchial provocation test (HBPT) and after bronchodilation test with either SCH 1000 or fenoterol by evaluating both SRAW and the slope of the alveolar plateau of nitrogen washout curve (N2 ph III)." | 3.67 | Comparative effects of SCH 1000 and fenoterol after histamine-induced bronchoconstriction in asymptomatic asthmatics. ( Bracamente, M; De Coster, A; Esposito-Iacenna, V; Gigliotti, F; Scano, G; Sergysels, R; Stendardi, L, 1984) |
"The effect of Fanetizole mesylate or CP-48,810, a new immunostimulating drug, on suppressor cell function and IgE synthesis in vitro was evaluated in atopic patients with allergic rhinitis and/or asthma and eczema." | 3.67 | Correction of an in vitro immunoregulatory defect in atopic subjects by the immunostimulating drug fanetizole mesylate (CP-48,810). ( Hemady, Z; Kiselis, I; Lima, M; Matloff, S; Rocklin, RE, 1984) |
"In order to determine the shape of the dose-response curves of the human airways to bronchial challenge, changes in forced expiratory volume in one second (FEV1) after inhaled histamine were measured in 8 current asthmatic, 2 mildly asthmatic, and 10 normal subjects." | 3.67 | The shape of the dose-response curve to histamine in asthmatic and normal subjects. ( Salome, CM; Woolcock, AJ; Yan, K, 1984) |
" method were studied in 30 patients with various forms of bronchial asthma and 6 healthy subjects, and the reactivity of rosette--forming T-lymphocytes was determined after stimulation by asthmopent, histamine and acetylcholine." | 3.67 | [Effect of beta-adrenergic mimetics and histamine on the capacity of T-lymphocytes from asthmatic patients and healthy persons to form E-rosettes]. ( Bozhkov, B; Dimitrov, V; Kosturkov, G; Slavov, S, 1984) |
"Nonspecific bronchial reactivity, involving inhaled challenges with methacholine and histamine and treadmill exercise challenge, were compared in 2 groups of steroid-requiring asthmatic children (9 to 15 yr of age) distinguished on the basis of marked differences in their typical time course of clinical deterioration leading to in-hospital management." | 3.67 | Comparison of responsiveness to methacholine, histamine, and exercise in subgroups of asthmatic children. ( Bhagat, RG; Grunstein, MM, 1984) |
"The effect of increasing concentrations of inhaled sodium cromoglycate (SCG) (2, 10, 20 and 40 g/l) on histamine and methacholine bronchial reactivity was studied in nine patients with extrinsic bronchial asthma." | 3.67 | Sodium cromoglycate in histamine and methacholine reactivity in asthma. ( Patel, KR, 1984) |
"The inhibition of immediate allergen or histamine induced airflow obstruction by inhaled ketotifen, clemastine, sodium cromoglycate, and placebo was studied in two groups of asthmatic subjects." | 3.67 | Effect of antihistamines and antiallergic drugs on responses to allergen and histamine provocation tests in asthma. ( Davies, RJ; Gould, C; Ollier, S; Phillips, MJ, 1984) |
" There was no significant difference between the polyp histamine levels in patients with a history of asthma, aspirin hypersensitivity, hay fever and positive skin tests." | 3.67 | Free histamine in nasal polyp fluid. ( Bickerton, R; Drake-Lee, AB; McLaughlan, P, 1984) |
"The histamine level of whole blood and plasma in asthmatic patients was estimated by means of a simple, sensitive and specific method, which was developed to measure low histamine levels." | 3.67 | The determination of blood histamine in asthmatic patients with a simple and sensitive method. ( Aoki, T; Hoshi, S; Izumi, H; Mue, S; Sato, H; Takishima, T, 1984) |
"Inhalation histamine dose-response curves were constructed 15 minutes after inhalation of saline placebo or verapamil (4 mg) for eight patients with mild atopic asthma in a double blind, random manner." | 3.67 | Effects of calcium channel blockade on histamine induced bronchoconstriction in mild asthma. ( Banks, J; Davies, BH; Fennerty, A; Walters, EH, 1984) |
"The effect of 1 mg inhaled prazosin on bronchoconstriction induced by methoxamine was investigated in seven asthmatic subjects." | 3.67 | The action of prazosin and propylene glycol on methoxamine-induced bronchoconstriction in asthmatic subjects. ( Black, JL; Salome, C; Shaw, J; Yan, K, 1984) |
"To assess the effect of an upper respiratory tract infection (URTI) on airway reactivity, histamine inhalation tests (HITs) were performed prospectively in 44 nonsmoking asthmatic (14) and nonasthmatic (30) volunteers." | 3.67 | Upper respiratory tract infections and airway reactivity in normal and asthmatic subjects. ( Breslin, AB; Jenkins, CR, 1984) |
"When ingested in acid solution, the preservative sodium metabisulfite (MB) provokes asthma within minutes of ingestion in a proportion of asthmatic subjects." | 3.67 | The relationship of inhaled sulfur dioxide reactivity to ingested metabisulfite sensitivity in patients with asthma. ( Allen, DH; Castle, WD; Delohery, J; Simmul, R, 1984) |
"In the present study the concentrations of IgE and histamine were determined in gingival tissue of patients with asthma (N = 15), patients with periodontitis (N = 21) and healthy controls (N = 18)." | 3.67 | Gingival IgE and histamine concentrations in patients with asthma and in patients with periodontitis. ( Hyyppä, T, 1984) |
"The mast cell disintegrating histamine releaser, compound 48/80, given daily for 5 days by aerosol to guinea pigs produced relative resistance to 48/80 induced asthma, but not to histamine induced asthma." | 3.67 | Desensitization to experimental asthma with 48/80. ( Ambrus, JL; Lillie, MA; Meky, NN, 1984) |
"The effects of voluntary coughs on specific conductance measurements were studied in normal, atopic and asthmatic subjects before and after bronchoconstriction with histamine." | 3.67 | Acute airway changes induced by coughing. ( Clark, TJ; Rees, PJ, 1984) |
"Inhaled adenosine causes bronchoconstriction in asthmatic patients." | 3.67 | Adenosine-induced bronchoconstriction in asthma. Antagonism by inhaled theophylline. ( Cushley, MJ; Holgate, ST; Tattersfield, AE, 1984) |
"In this study we have examined the relationship between the bronchial response to inhaled histamine and the bronchial response to breathing cold air at rest in nine control subjects and nine patients with asthma." | 3.67 | Relationship between bronchial response to respiratory heat exchange and nonspecific airways reactivity in asthmatic patients. ( Cockcroft, DW; Cotton, DJ; Dosman, JA; Hodgson, WC; Werner, GD, 1984) |
"In 23 children with asthma and 18 healthy controls, cold air challenge ( CACh ) was done twice during the same half day, and in the asthmatics a third time together with a histamine challenge (HCh) 2 wk later." | 3.67 | Cold air challenge of airway hyperreactivity in children: practical application and theoretical aspects. ( Kroisel, P; Kump, H; Polgar, G; Zach, M, 1984) |
"We have measured plasma histamine, serum neutrophil chemotactic activity (NCA) and complement (C3 and C4) over a 24-hour period in patients experiencing either early- and late-phase (dual) or single early asthmatic reactions to inhaled allergens." | 3.67 | Immunologic studies in allergen-induced late-phase asthmatic reactions. ( Cooper, P; Cromwell, O; Durham, SR; Kay, AB; Lee, TH; Merrett, J; Merrett, TG; Shaw, RJ, 1984) |
"Bronchial reactivity after Cimetidine treatment was evaluated by the histamine provocation test in 24 patients with atopic bronchial asthma and 10 patients with peptic ulcer." | 3.67 | Bronchial hyper-reactivity in atopic patients during H2-receptor blocker treatment. ( Bortkiewicz, J; Chyrek-Borowska, S; Hofman, J; Rutkowski, R; Siergiejko, Z, 1986) |
"Allergen-mediated histamine release from human leukocytes represents an important model for in vitro studies of allergic reactions." | 3.67 | Histamine-dependent allergy blood test. Clinical evaluation. ( Camp, VM; Faraj, BA; Lolies, P, 1986) |
" We assessed mast-basophiloid cell numbers and histamine levels with a sensitive histamine assay, lower limit of sensitivity, 25 pg/ml, in BAL fluid from normal individuals (n = 9) and compared these results to those obtained from patients with sarcoidosis (n = 31), idiopathic pulmonary fibrosis (IPF) (n = 8), and mild asthma (n = 7)." | 3.67 | Histamine levels in bronchoalveolar lavage from patients with asthma, sarcoidosis, and idiopathic pulmonary fibrosis. ( Kaliner, M; Rankin, JA; Reynolds, HY, 1987) |
"The effects of 2,3,5-trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-1,4-benzoquinone (AA-861), a selective 5-lipoxygenase inhibitor, on immunological or non-immunological release of slow reacting substance of anaphylaxis (SRS-A) and histamine and its effects on experimental asthma were investigated." | 3.67 | Effect of AA-861, a selective 5-lipoxygenase inhibitor, on models of allergy in several species. ( Kohno, SW; Nanbu, F; Negi, H; Ohata, K; Taira, M; Yamamura, H, 1988) |
"Spontaneous histamine release (SHR) from basophils by simple incubation at 37 degrees C for 60 minutes and histamine content of basophils were assessed in normal subjects, patients with asthma, and methacholine-sensitive subjects without asthma (NAMS)." | 3.67 | Spontaneous histamine release and histamine content in normal subjects and subjects with asthma. ( Akagi, K; Townley, RG, 1989) |
"A sulpyrin inhalation test was given to 13 patients with aspirin-induced asthma (AIA) and 8 patients with non-aspirin-induced asthma (non-AIA) to observe the changes in plasma histamine levels before and after challenges." | 3.67 | [The changes in plasma histamine levels after a sulpyrin inhalation test in asthmatic patients]. ( Adachi, M; Kokubu, F; Maeda, M; Okada, Y; Takahashi, T; Tanabe, Y; Tsuji, A, 1989) |
"In this study we investigated the effect of the selective and potent thromboxane A2 (TxA2) receptor antagonist GR32191 on smooth muscle contraction induced by the TxA2 analogue U46619, prostaglandin (PG) D2, PGF2 alpha, and methacholine (MCh) in guinea pig airways in vitro and the airways response provoked by inhaled PGD2 and MCh in asthmatic subjects in vivo." | 3.67 | Effect of a thromboxane receptor antagonist on PGD2- and allergen-induced bronchoconstriction. ( Beasley, RC; Church, MK; Featherstone, RL; Harris, A; Holgate, ST; Rafferty, P; Robinson, C; Varley, JG, 1989) |
" Both subjects had rhinitis and asthma limited to the ragweed season, near normal out-of-season histamine PC20, and extreme IgE sensitivity to ragweed." | 3.67 | Appearance of allergen-induced increases in airway responsiveness only after repeated allergen inhalations in two subjects. ( Cockcroft, DW; Hargreave, FE; Ruffin, RE, 1989) |
"Studies have demonstrated that increased amounts of histamine in the airways of asthmatic patients are associated with increased airway reactivity." | 3.67 | Use of segmental airway lavage to obtain relevant mediators from the lungs of asthmatic and control subjects. ( Casale, TB; Floerchinger, C; Hunninghake, GW; Richerson, HB; Wood, D; Zehr, BB, 1989) |
"Airway responsiveness to histamine and leukotriene E4 (LTE4) has been compared between five subjects with aspirin-induced asthma (AIA) and 15 asthmatic subjects without aspirin sensitivity (non-AIA)." | 3.67 | Airway responsiveness to histamine and leukotriene E4 in subjects with aspirin-induced asthma. ( Arm, JP; Lee, TH; O'Hickey, SP; Spur, BW, 1989) |
"We examined the effects of a new antiasthmatic drug, azelastine, on the electromechanical responses of airway smooth muscle to histamine, acetylcholine (ACh), and tetraethylammonium (TEA)." | 3.67 | Azelastine inhibits agonist-induced electromechanical activity in canine tracheal muscle. ( Lee, HK; Sperelakis, N, 1989) |
"We measured the plasma histamine concentration in patients with bronchial asthma by the post-column derivatization method developed by Yamatodani." | 3.67 | [Application of HPLC to measurement of plasma histamine in bronchial asthma]. ( Hasegawa, T; Satake, T; Suzuki, R; Takagi, K; Watanabe, T; Yamaki, K; Yamatodani, A, 1989) |
"The prevalence of atopic diseases and bronchial reactivity to histamine and methacholine was determined in 36 patients with bronchiectasis and in 36 control patients matched for age, sex, and smoking history." | 3.67 | Prevalence of asthma, atopy, and bronchial hyperreactivity in bronchiectasis: a controlled study. ( Chan, HS; Pang, J; Sung, JY, 1989) |
"Fifty-two of 95 smokers with a forced expiratory volume in one second (FEV1) above 70% predicted and with chronic bronchitis were found to have increased bronchial responsiveness, expressed as PC20FEV1, upon challenge with inhaled histamine." | 3.67 | A comparison of airway responsiveness in smokers with chronic bronchitis and in asthmatic subjects. ( Engel, T; Hansen, M; Heinig, JH; Madsen, O; Weeke, ER, 1989) |
" We investigated whether these receptors may be involved in feedback inhibition of cholinergic reflex bronchoconstriction induced by sulfur dioxide (SO2) in seven nonasthmatic atopic subjects and in six mild asthmatic subjects." | 3.67 | A muscarinic agonist inhibits reflex bronchoconstriction in normal but not in asthmatic subjects. ( Barnes, PJ; Dixon, CM; Lammers, JW; McCusker, MT; Minette, PA, 1989) |
"The effect of two consecutive histamine inhalation challenges on airways responsiveness was assessed in a group of eight nonsmoking nonmedicated asthmatics aged 19-27 yr." | 3.67 | Airways responsiveness determined by consecutive histamine challenges in asymptomatic asthmatics. ( Burki, NK; Küng, M; Scott, GC, 1989) |
"The aim of the study was to investigate the influence of verapamil on anti-IgE induced histamine release from basophils isolated from the blood of 10 atopic asthma patients." | 3.67 | The influence of the calcium channel antagonist verapamil on histamine release from target cells. ( Chyrek-Borowska, S; Hofman, J; Siergiejko, Z, 1989) |
"In order to elucidate the working mechanisms of immunotherapy (IT), the in vitro productions of histamine, prostaglandin E2 (PGE2) and leukotriene C4 (LTC4) were studied in 18 newly diagnosed and 20 hyposensitized (greater than 2 yr) asthmatic children." | 3.67 | The effect of immunotherapy on the in vitro productions of histamine, prostaglandin E2 and leukotriene C4 in asthmatic children. ( Hsieh, KH; Wang, JY, 1989) |
" Since bronchoscopy was performed after pretreatment with atropine and under topical anesthesia with lignocaine, histamine chloride tests were also performed in 6 asthmatics before and after atropine, and in 6 asthmatics before and after local anesthesia with lignocaine." | 3.67 | Flexible fiberoptic bronchoscopy does not alter airway responsiveness. ( Lundgren, R; Söderberg, M, 1989) |
"The effect of histamine or methacholine inhalational challenge on breathing patterns and oxygen saturation was investigated in ten stable asthmatic patients." | 3.67 | Effect of bronchial challenge on breathing patterns and arterial oxygenation in stable asthma. ( Catterall, JR; Douglas, NJ; Flenley, DC; Parker, A; Stewart, IC, 1989) |
"4 mg salbutamol on the impedance of the respiratory system was studied in 25 asthmatic subjects after histamine-induced bronchoconstriction." | 3.67 | Response localization of the pharmacological agents histamine and salbutamol along the respiratory system by forced oscillations in asthmatic subjects. ( Polko, AH; Visser, BF; Wouters, EF, 1989) |
"The airway responses to histamine, exercise and ultrasonically nebulized hypertonic saline have been compared in ten asthmatic patients." | 3.67 | Airway responses to hypertonic saline, exercise and histamine challenges in bronchial asthma. ( Belcher, NG; Lee, TH; Rees, PJ, 1989) |
"The content of acetylcholine, histamine and the total amount of catecholamines were measured in blood of 33 patients with bronchial asthma, in 6 patients with preasthma and in 10 practically normal subjects before and after the use of graded exercise (bicycle ergometry)." | 3.67 | [The effect of exercise on the content of biogenic amines and acetylcholine of the blood in bronchial asthma patients]. ( Dotsenko, EK; Goncharova, VA; Mamedov, DT; Sinitsina, TM, 1989) |
"Examination of 155 patients with atopic, infection-dependent bronchial asthma (BA) and chronic asthmatic bronchitis in the phase of the disease exacerbation and remission has shown that hyperhistaminemia is common not only to atopic but also to infection-dependent BA." | 3.67 | [Mast-cell mechanism of the pathogenesis of bronchial asthma and peroxidation of membrane lipids]. ( Amatuni, VG; Egoian, AK; Narimanov, MZ; Zil'fian, AV, 1989) |
"The effects of cimetidine and ranitidine on the bronchial reactivity in the group of 10 patients with atopic bronchial asthma are presented." | 3.67 | Comparison of the effects of cimetidine and ranitidine in histamine provocation tests in atopic asthma. ( Hofman, J; Michalska, I; Rutkowski, R, 1989) |
"Ten patients with bronchial asthma were challenged with histamine before and after receiving saline and active drug (levomepromazine or antazoline) (a total of six challenges)." | 3.67 | Levomepromazine (Nozinan) reduces nonspecific bronchial hyperreactivity in asthmatics. ( Faurschou, P; Madsen, F; Pals, H; Rosetzsky, A, 1989) |
"Airway reactivity to histamine was determined in a group of non-asthmatic and asthmatic patients prior to thoracotomy." | 3.67 | Human isolated bronchial muscle preparations from asthmatic patients: effects of indomethacin and contractile agonists. ( Benveniste, J; Brink, C; Cerrina, J; Haye-Legrande, I; Labat, C; Raffestin, B, 1989) |
" We determined the decrease in maximal expiratory flow rates (Vmax) from partial and maximal flow-volume curves in seven asthmatic subjects after inhalation of aerosols of histamine or leukotriene C4 (LTC4) while breathing air or a mixture of 80% helium and 20% oxygen (He/O2)." | 3.67 | Localization of the site of the bronchoconstrictor effects of leukotriene C4 compared with that of histamine in asthmatic subjects. ( Austen, KF; Corey, EJ; Drazen, JM; Ingram, RH; Lafleur, JE; Pichurko, BM; Sperling, RI, 1989) |
"Acetylcholine, serotonin, and histamine levels have been measured in exhaled air humor condensate in 65 patients aged 18 to 60, 44 ones with bronchial asthma and 21 with preasthma." | 3.67 | [Biologically active substance levels in exhaled air from patients with pre-asthma and bronchial asthma]. ( Dotsenko, EK; Goncharova, VA; Mamedov, DT, 1989) |
"Bronchial responsiveness assessed by histamine bronchial challenge testing in 22 children with chronic stable asthma was compared with the number of inflammatory cells per milliliter of broncholavage fluid obtained by fiberoptic bronchoscopy." | 3.67 | Bronchial hyperresponsiveness in asthmatic children. Correlation with macrophages and eosinophils in broncholavage fluid. ( Ferguson, AC; Wong, FW, 1989) |
"The relative bronchoconstricting potencies of leukotriene E4 (LTE4) methacholine and histamine have been compared in asthmatic and normal subjects." | 3.67 | The relative responsiveness to inhaled leukotriene E4, methacholine and histamine in normal and asthmatic subjects. ( Arm, JP; Lee, TH; O'Hickey, SP; Rees, PJ; Spur, BW, 1988) |
"The disparity between the activation of mast cells in the airways of patients with allergic asthma and the lack of efficacy of H1-antihistamines in asthma therapy has been difficult to reconcile." | 3.67 | Astemizole and other H1-antihistaminic drug treatment of asthma. ( Emanuel, MB; Holgate, ST; Howarth, PH, 1985) |
"In 12 asthmatic (A) and ten normal (N) subjects, we measured the effect of inhaled saline solution, acetylcholine, histamine (H), and chlorpheniramine (CP) on specific airway conductance and forced exploratory flows." | 3.67 | Pharmacodynamic aspects of chlorpheniramine-induced bronchodilatation. ( Popa, V, 1988) |
"To assess the role of histamine as a mediator in the response to exercise and isocapnic hyperventilation of cold air (IHCA) in asthma, we studied nine asthmatic subjects, age 13 to 25 years." | 3.67 | Effect of terfenadine on the response to exercise and cold air in asthma. ( Chernick, V; Montgomery, M; Pasterkamp, H; Poynter, A; Wiebicke, W, 1988) |
"The changes in transcutaneous oxygen saturation (SaO2%) and airway responses to inhaled histamine and leukotriene C4 (LTC4) were examined in 10 asthmatic patients, and the effect of inhaled LTC4 (16 nmol) on cardiopulmonary hemodynamics was examined in seven nonasthmatic patients undergoing diagnostic cardiac catheterization." | 3.67 | Effect of inhaled leukotriene C4 on cardiopulmonary function. ( Albazzaz, MK; Dargie, HJ; Patel, KR; Reid, JM; Shakir, S, 1989) |
"To investigate possible mediator interaction in asthma, the effect of inhaled leukotriene (LT) C4 on bronchoconstriction provoked by histamine and prostaglandin (PG) D2 was studied in nine asthmatic subjects." | 3.67 | Interaction of inhaled LTC4 with histamine and PGD2 on airway caliber in asthma. ( Holgate, ST; Phillips, GD, 1989) |
"In 12 asthmatic children, aged 8-14 years, we investigated the possibility of using a provocation concentration of histamine (PC) causing a 10% or 15% fall in baseline forced expiratory volume in 1 sec (FEV1), instead of a PC20 histamine, in the assessment of bronchial hyperreactivity." | 3.67 | The reproducibility and agreement of three indices of airway responsiveness to histamine in asthmatic children. ( Gerritsen, J; Knol, K; Koëter, GH; Postma, DS; van Aalderen, WM; van der Weele, LT, 1989) |
"To determine whether refractoriness to histamine induced bronchoconstriction occurs, 20 asthmatic subjects aged 19-50 years were tested." | 3.67 | Refractory period following bronchoconstriction provoked by histamine in asthmatic subjects. ( Avery, AJ; Connolly, MJ; Hendrick, DJ; Stenton, SC; Walters, EH, 1989) |
"The relation between airway responsiveness to propranolol and histamine was studied in 32 asthmatic children." | 3.67 | Propranolol inhalation challenge in relation to histamine response in children with asthma. ( Gerritsen, J; Knol, K; Koëter, GH; Vander Weele, LT, 1988) |
"There is widespread belief that methacholine responsiveness in asthmatic subjects is closely related to histamine responsiveness, and that the two agents may be used interchangeably in the measurement of non-specific bronchial responsiveness (NSBR)." | 3.67 | The relationship between bronchial responsiveness to methacholine and bronchial responsiveness to histamine in asthmatic subjects. ( Avery, AJ; Connolly, MJ; Hendrick, DJ; Walters, EH, 1988) |
"Adenosine, when it is administered by inhalation to asthmatic subjects, is a potent bronchoconstrictor, although its mechanism of action is not known." | 3.67 | Adenosine-induced bronchoconstriction in asthma: role of mast cell-mediator release. ( Cushley, MJ; Holgate, ST, 1985) |
"The adenylate cyclase response to histamine was measured in lymphocyte membranes of allergic asthmatic patients and healthy control subjects, just before and 24 h after inhalation challenge with house dust mite allergen." | 3.67 | Reduced adenylate cyclase responsiveness to histamine in lymphocyte membranes of allergic asthmatic patients after allergen challenge. ( de Vries, K; Folkers, B; Kauffman, HF; Koëter, GH; Meurs, H; Timmermans, A, 1985) |
"Adenosine by inhalation causes bronchoconstriction in asthmatic but not in normal subjects by an undefined mechanism." | 3.67 | Adenosine-induced bronchoconstriction in asthma. Role of parasympathetic stimulation and adrenergic inhibition. ( Cushley, MJ; Holgate, ST; Mann, JS, 1985) |
"Challenges with ouabain and histamine were performed a week apart in 10 patients with asthma and 5 normal subjects." | 3.67 | Airway responses to inhaled ouabain in subjects with and without asthma. ( Agrawal, KP; Hyatt, RE; Imber, WE; Krell, WS; Reed, CE, 1986) |
"Adenylate cyclase responses to isoproterenol, histamine, 5'-guanylylimidodiphosphate (GppNHp) and NaF were measured in lymphocyte membranes of allergic asthmatic patients and healthy control subjects, just before and 24 h after inhalation challenge with house dust mite allergen or histamine." | 3.67 | Specific immunological modulation of lymphocyte adenylate cyclase in asthmatic patients after allergenic bronchial provocation. ( de Monchy, JG; de Vries, K; Kauffman, HF; Koëter, GH; Meurs, H; Timmermans, A, 1986) |
"The bronchoconstrictor activity of an aerosol of leukotriene E4(LTE4) was compared with that of histamine in 5 normal and in 6 asthmatic subjects to define the relative potency of LTE4 between the groups using 3 indices of airway response." | 3.67 | Bronchoconstrictor effects of leukotriene E4 in normal and asthmatic subjects. ( Austen, KF; Corey, EJ; Davidson, AB; Drazen, JM; Ingram, RH; Lee, TH; McFadden, ER; Scanlon, PD; Solway, J, 1987) |
"Histamine-binding proteins have been isolated from healthy subjects and patients with endogenous bronchial asthma." | 3.67 | Histamine binding proteins identified in healthy subjects and asthmatic patients. ( Liebhart, E; Liebhart, J; Małolepszy, J; Szeliga, W; Zak-Nejmark, T, 1986) |
"The arylsulfatase activity and histamine concentration of bronchoalveolar lavage fluid (BALF) were examined in patients with bronchial asthma in relation to the eosinophil count and asthma type (atopic and non-atopic)." | 3.67 | Eosinophilic leucocytes and arylsulfatase activity in bronchoalveolar lavage fluid of patients with bronchial asthma. ( Araki, H; Kimura, I; Kitani, H; Oki, K; Sudo, M; Takahashi, K; Tanizaki, Y; Tsuji, M, 1988) |
"Serum neutrophil chemotactic activity (NCA) and plasma histamine concentrations were measured in 9 asthmatic subjects with exercise-induced asthma after inhalation challenge with ultrasonically nebulized 3." | 3.67 | A comparison of mediator and catecholamine release between exercise- and hypertonic saline-induced asthma. ( Belcher, NG; Clark, TJ; Dalton, N; House, FR; Lee, TH; Murdoch, RD; Rees, PJ, 1988) |
"Tachyphylaxis occurs to repeated challenges with inhaled histamine but not with inhaled acetylcholine in asthmatic subjects." | 3.67 | Histamine bronchoconstriction reduces airway responsiveness in asthmatic subjects. ( Manning, PJ; O'Byrne, PM, 1988) |
"Both exercise and histamine inhalation cause bronchoconstriction in asthmatic subjects." | 3.67 | Exercise refractoriness after histamine inhalation in asthmatic subjects. ( Hamielec, CM; Manning, PJ; O'Byrne, PM, 1988) |
"The effects of various doses of inhaled MgSO4 on the histamine bronchoprovocation test were studied in nine asthmatics in clinical remission (FEV1 greater than 80% of predicted)." | 3.67 | Dose-related effect of inhaled magnesium sulfate on histamine bronchial challenge in asthmatics. ( Bucca, C; Caria, E; Rolla, G, 1988) |
"This study was undertaken in order to assess the neural drive to the respiratory muscles and the inspiratory neuromuscular coupling in patients with bronchial asthma during histamine-induced bronchoconstriction." | 3.67 | Changes in neural drive (EMGd) and neuromuscular coupling during histamine-induced bronchoconstriction in patients with asthma. ( Arcangeli, P; Duranti, R; Gigliotti, F; Gorini, M; Scano, G; Spinelli, A, 1988) |
"To investigate the mechanisms contributing to refractoriness in exercise-induced asthma (EIA), airway responsiveness to histamine was studied in eight asthmatic patients." | 3.67 | Airway responsiveness to histamine in patients refractory to repeated exercise. ( Carpentiere, G; Castello, F; Marino, S, 1988) |
"We investigated immediate and late changes in airway responsiveness to histamine, after bronchoconstriction due to exercise combined with inhalation of cold air, in ten asthmatic subjects who came on six days." | 3.67 | Bronchoconstriction due to exercise combined with cold air inhalation does not generally influence bronchial responsiveness to inhaled histamine in asthmatic subjects. ( Cartier, A; Ghezzo, H; Malo, JL; Martin, RR; Tessier, P, 1988) |
"The relation between the pathochemical phase and the histaminergic reactivity of the effector structures in asthmatic patients was studied." | 3.67 | [The blood histamine level of patients with bronchial asthma and their skin vascular reaction to histamine]. ( Kosturkov, G; Vŭlcheva, T, 1988) |
"The effects of repeated exercise-induced bronchospasm on nonspecific (nonallergenic) bronchial responsiveness (NSBR) to histamine were studied in 12 asthmatic patients (6 F, 6 M)." | 3.67 | Bronchial responsiveness to histamine after repeated exercise-induced bronchospasm. ( Boulet, LP; Legris, C; Turcotte, H, 1987) |
"The reproducibility of the changes in FEV, induced by inhalation of histamine, was studied in adult asthmatics." | 3.67 | Reproducibility of histamine inhalation in asthmatics. ( Bundgaard, A; Schmidt, A, 1986) |
"Nine adult asthmatics were challenged with histamine four times during the same day, at 07." | 3.67 | Histamine challenge in asthmatics at 07.00-12.00-17.00 and 22.00 h. ( Andersen, KK; Bundgaard, A, 1986) |
"The immediate changes in regional ventilation and pulmonary blood flow were studied in seventeen adults with perennial asthma and in two control persons, who were challenged by histamine inhalation (histamine induced asthma (HIA))." | 3.67 | Regional V/Q changes in asthmatics after histamine inhalation. ( Bundgaard, A; Munkner, T, 1986) |
" When inhaled by asthmatic subjects, 9 alpha,11 beta-PGF2 was a potent bronchoconstrictor agent, being approximately equipotent with PGD2 and 28-32 times more potent than histamine (P less than 0." | 3.67 | 9 alpha,11 beta-prostaglandin F2, a novel metabolite of prostaglandin D2 is a potent contractile agonist of human and guinea pig airways. ( Beasley, CR; Church, MK; Featherstone, RL; Hardy, CC; Holgate, ST; Robinson, C; Varley, JG, 1987) |
"The predictive value of a bronchial challenge with histamine was determined in a prospective survey on a population with a high prevalence of asthma (0." | 3.67 | Bronchial histamine challenge in the diagnosis of asthma. The predictive value of changes in airway resistance determined by the interrupter method. ( Frølund, L; Holstein-Rathlou, NH; Madsen, F; Svendsen, UG; Weeke, B, 1986) |
"The bronchial response to inhaled histamine has been suggested as an epidemiological tool for assessing the prevalence of asthma, though the exact relationship between reactivity and asthma is unknown." | 3.67 | Descriptive epidemiology of bronchial reactivity in an adult population: results from a community study. ( Anderson, F; Britton, JR; Burney, PG; Chinn, S; Corfield, DR; Kelson, MC; Papacosta, AO; Tattersfield, AE, 1987) |
"In order to explore the relationship between bronchial hyperresponsiveness (BHR) to inhaled histamine, respiratory symptoms and diagnosed asthma in children, we undertook a cross-sectional study of 2363 Australian schoolchildren aged 8-11 years." | 3.67 | Bronchial hyperresponsiveness in two populations of Australian schoolchildren. I. Relation to respiratory symptoms and diagnosed asthma. ( Britton, WJ; Peat, JK; Salome, CM; Woolcock, AJ, 1987) |
"Adenosine, AMP, and ADP all caused similar concentration-related bronchoconstriction when inhaled by patients with asthma, whereas the adenosine hydrolysis product inosine had no effect." | 3.67 | Airway effects of purine nucleosides and nucleotides and release with bronchial provocation in asthma. ( Cushley, MJ; Holgate, ST; Mann, JS; Renwick, AG, 1986) |
"The effect of bradykinin was studied by inhalation in normal and asthmatic human subjects, as well as on human bronchial smooth muscle in vitro." | 3.67 | Bradykinin-induced bronchoconstriction in humans. Mode of action. ( Barnes, PJ; Cuss, FM; Dixon, CM; Fuller, RW, 1987) |
"Using a sensitive single isotope enzymatic assay we measured bronchoalveolar lavage (BAL) fluid histamine in asymptomatic normal (nonallergic), allergic rhinitic, and allergic asthmatic subjects." | 3.67 | Elevated bronchoalveolar lavage fluid histamine levels in allergic asthmatics are associated with methacholine bronchial hyperresponsiveness. ( Casale, TB; Hunninghake, GW; Metzger, WJ; Richerson, HB; Trapp, S; Wood, D; Zavala, D, 1987) |
"Factors that influence the time necessary for complete recovery of FEV1 after inhaling histamine were analysed in forty-five children with asthma." | 3.67 | Recovery of FEV1 after histamine challenge in asthmatic children. ( Akkerboom, HJ; Gerritsen, J; Knol, K; Koëter, GH, 1987) |
"Polyvalent killed influenza virus vaccine or saline was administered subcutaneously to 27 asthmatics to investigate the effect of influenza vaccine on respiratory function and on airway responsiveness to inhaled histamine." | 3.67 | Unchanged bronchial reactivity after killed influenza virus vaccine in adult asthmatics. ( Karjalainen, J; Kava, T; Laitinen, LA; Lindqvist, A, 1987) |
"Histamine inhalation provocation tests were performed in 18 asymptomatic asthmatic patients with progressively increasing doses of a pressurized aerosol of histamine phosphate." | 3.67 | Inspiratory impedance during histamine-induced bronchoconstriction in patients with bronchial asthma. ( Duranti, R; Gigliotti, F; Gorini, M; Lo Conte, C; Scano, G; Scibilia, MR; Spinelli, A, 1987) |
"We measured bronchoalveolar lavage (BAL) fluid histamine levels in allergic asthmatics and nonallergic normal subjects after local airway antigen and cold 22 degrees C normal saline challenges." | 3.67 | Direct evidence of a role for mast cells in the pathogenesis of antigen-induced bronchoconstriction. ( Casale, TB; Hunninghake, GW; Richerson, HB; Wood, D; Zavala, D; Zehr, B, 1987) |
"The bronchoconstriction induced by repeated histamine inhalation tests was studied in eight mild stable asthmatic subjects to determine whether histamine tachyphylaxis occurs in asthmatics." | 3.67 | Tachyphylaxis to inhaled histamine in asthmatic subjects. ( Jones, GL; Manning, PJ; O'Byrne, PM, 1987) |
"To study the ability of cutaneous mast cells to degranulate in urticaria-prone patients, subjects were skin tested with the known mast cell degranulator, codeine sulfate." | 3.67 | Discrimination between urticaria-prone and other allergic patients by intradermal skin testing with codeine. ( Cohen, RW; Rosenstreich, DL, 1986) |
"Skin prick and intracutaneous tests were performed with serotonin, histamine and a mixture of both in 32 normal persons, two rhinitis patients and 12 asthmatics." | 3.67 | Intracutaneous and skin prick testing with serotonin and histamine. ( Tønnesen, P, 1986) |
" Histamine aerosol significantly increased Rnaw in healthy subjects, asthmatics and asthmatics with allergic rhinitis." | 3.67 | Effects of pulmonary inhalation of water and histamine aerosols on nasal airflow resistance in man. ( Bundgaard, A; Schmidt, A; Syabbalo, NC; Widdicombe, JG, 1986) |
"Nasal mucociliary transport time, nasal hypersensitivity to histamine, the number of basophils and eosinophils in the superficial mucous layer of the inferior turbinate, and the amount of histamine in the nasal secretion were measured in the asthmatic children with subclinical nasal allergy (asthma group)." | 3.67 | Pathophysiological condition of the nose of asthmatic children with subclinical nasal allergy. ( Miyoshi, Y; Sakakura, Y; Uchida, Y; Ukai, K, 1986) |
"To study the effect of inhaled clonidine on broncho-obstruction in asthmatics, 10 patients with extrinsic asthma were broncho-provoked twice with an allergen that had been shown to give positive skin prick test results." | 3.67 | The effect of inhaled clonidine in patients with asthma. ( Andersson, RG; Ekström, T; Lindgren, BR, 1986) |
" In order to evaluate the relative contribution of vagal and non-vagal afferences to increasing neural drive to the respiratory muscles in 14 asymptomatic asthmatic patients known to be responsive (decrease in FEV1 greater than 20% of the control values) to previous bronchial provocation test (BPT) with aerosolized histamine, we evaluated FEV1, breathing pattern and neuromuscular drive, as assessed by mouth occlusion pressure (PO." | 3.67 | Effects of histamine and reproterol inhalation on mouth occlusion pressure in patients with bronchial asthma. ( Arcangeli, P; Duranti, R; Emmi, L; Gigliotti, F; Lo Conte, C; Scano, G; Spinelli, A; Stendardi, L; Turco, R, 1986) |
"To determine whether bronchial reactivity is augmented soon after an allergen-induced immediate asthmatic response, we compared reactivity to histamine before and immediately upon resolution of the immediate asthmatic response in seven subjects with mild asthma who were known to develop dual asthmatic responses after inhalation of Kentucky bluegrass allergen." | 3.67 | Bronchial reactivity increases soon after the immediate response in dual-responding asthmatic subjects. ( Bernstein, IL; Murlas, CG; Steinberg, D; Thorpe, JE, 1987) |
" In vivo and in vitro studies were conducted to discover whether peptide modifies basic function and/or bronchial spasm provoked by histamine." | 3.67 | [The nonadrenergic noncholinergic system in the regulation of bronchial tonus]. ( Bottino, G; Gianotti, A; Moscatelli, P, 1986) |
"Histamine inhalation challenge was performed in 32 asthmatic children aged 6 through 13, 20 control children aged 8 through 14, and 16 control adults aged 24 through 37 years." | 3.67 | [Evaluation of the bronchial provocation test with histamine in asthmatic children]. ( Azcárate, MJ; Salazar, M; Vázquez Cordero, C, 1986) |
"Recent advances in the use of inhalation provocation tests in the clinical evaluation of asthma have been made with methacholine and histamine tests." | 3.67 | Advances in the use of inhalation provocation tests in clinical evaluation. ( Hargreave, FE; Juniper, EF; Ramsdale, EH; Sterk, PJ, 1985) |
"We measured laryngeal resistance (Rla), upper airway resistance (Ruaw), and lower respiratory resistance below the larynx (Rlrs) during methacholine and histamine provocation in 10 normal and 12 asthmatic subjects." | 3.67 | Upper airway response during bronchoprovocation and asthma attack. ( Hida, W; Sasaki, H; Sekizawa, K; Shindoh, C; Takishima, T, 1985) |
"Asthma was provoked by histamine inhalation in five children in order to study the hypoxaemia that might ensue and the underlying ventilation-perfusion (VA/Q) mismatching." | 3.67 | Histamine-induced asthma in children: effects on the ventilation-perfusion relationship. ( Freyschuss, U; Hedenstierna, G; Hedlin, G, 1985) |
"We evaluated isocapnic hyperventilation with room temperature gas (IHV) as a test of bronchial hyperreactivity and compared it with histamine challenge (HC) in three groups of subjects: normal subjects, known mild asthmatic patients, and patients referred to the pulmonary clinic for a chief complaint of dyspnea." | 3.67 | Bronchial challenge with room temperature isocapnic hyperventilation. A comparison with histamine challenge. ( Heimer, D; Scharf, SM; Walters, M, 1985) |
"Nonspecific bronchial reactivity to exercise and histamine was measured in nine children with asthma before and within nine days after allergen inhalation." | 3.67 | Increased bronchial responsiveness to exercise and histamine after allergen challenge in children with asthma. ( Godfrey, S; Mussaffi, H; Springer, C, 1986) |
"The present studies were undertaken to obtain histamine (HIST) dose-response curves for tracheal smooth muscle (TSM) from an actively ragweed-sensitized canine model of asthma and to compare these results with 1) HIST dose-response data from littermate control dogs, 2) initially nonsensitized TSM passively sensitized (in vitro) to ragweed and 3) the dose-response curve to an agonist that opens primarily voltage-sensitive calcium channels, i." | 3.67 | Effect of atropine on the hyperresponsiveness of ragweed-sensitized canine tracheal smooth muscle. ( Antonissen, LA; Kepron, W; Kroeger, EA; Mitchell, RW; Stephens, NL, 1986) |
"In a group of aspirin-sensitive asthmatics we studied skin weal and flare responses to intradermal injections of compound 48/80 and histamine during oral aspirin (ASA) provocation and after ASA "desensitisation"." | 3.67 | The effect of aspirin during aspirin "desensitisation" on compound 48/80 and histamine-induced skin responses in aspirin-sensitive asthmatics. ( Grzelewska-Rzymowska, I; Kowalski, ML; Rozniecki, J; Szmidt, M, 1985) |
"We measured bronchial reactivity to inhaled histamine and prepared electron micrographs from bronchial biopsies from 8 asthmatic patients who never smoked (2 females, 6 males, 18 to 62 yr of age)." | 3.67 | Damage of the airway epithelium and bronchial reactivity in patients with asthma. ( Haahtela, T; Heino, M; Kava, T; Laitinen, A; Laitinen, LA, 1985) |
"In order to investigate the role of histamine in the late asthmatic reaction (LAR) following house-dust mite (HDM) inhalation, we studied, with hourly intervals, urinary N tau-methylhistamine (an important metabolite of histamine) in 14 allergic asthmatic patients before and after broncho provocation with HDM." | 3.67 | Histamine in late asthmatic reactions following house-dust mite inhalation. ( Beaumont, F; de Monchy, JG; de Vries, K; Kauffman, HF; Keyzer, JJ, 1985) |
"Twenty seven aspirin sensitive asthmatic patients were studied to determine the relationship between non-specific bronchial responsiveness to inhaled histamine and the degree of sensitivity to aspirin (aspirin threshold dose)." | 3.67 | Bronchial hyperreactivity to histamine in aspirin sensitive asthmatics: relationship to aspirin threshold and effect of aspirin desensitisation. ( Grzelewska-Rzymowska, I; Kowalski, ML; Rozniecki, J; Szmidt, M, 1985) |
"The time course of recovery from airway response induced by the inhalation of progressively doubling doses of histamine phosphate (3 to 4 depending on the subject) was studied in 8 asthmatic subjects by serial measurements of lung resistance (RL)." | 3.67 | Kinetics of the recovery of airway response caused by inhaled histamine. ( Cartier, A; Gauthier, R; Ghezzo, H; Lemire, I; Malo, JL; Martin, RR, 1985) |
"The effect of intravenous infusion of dipyridamole on histamine- and adenosine-induced bronchoconstriction was studied in 6 normal and 6 allergic asthmatic subjects." | 3.67 | The effect of dipyridamole on histamine- and adenosine-induced bronchoconstriction in normal and asthmatic subjects. ( Cushley, MJ; Holgate, ST; Tallant, N, 1985) |
"The mechanism of propranolol induced bronchoconstriction in asthma is uncertain, as airway beta adrenoceptors are not innervated by sympathetic nerves and circulating adrenaline concentrations are not raised." | 3.67 | Plasma histamine concentration during propranolol induced bronchoconstriction. ( Barnes, PJ; Brown, MJ; Dollery, CT; Ind, PW, 1985) |
"The effects of histamine, antihistamines, isoproterenol and theophylline on the expressions of Fc and complement (C') receptors on the polymorphonuclear leukocytes (PMN's) were studied in 40 asthmatic children." | 3.66 | The effects of histamine, antihistamines, isoproterenol and theophylline on the Fc and complement receptor functions of polymorphonuclear leukocytes in asthmatic children. ( Hsieh, KH, 1981) |
"The bronchodilatory response of three beta 2-agonists (fenoterol, salbutamol, and terbutaline), administered by a metered aerosol inhaler, was assessed in 19 asthmatic children after histamine-induced bronchoconstriction." | 3.66 | Mode of action of bronchodilating drugs on histamine-induced bronchoconstriction in asthmatic children. ( Duquenne, D; Geubelle, F; Kraemer, R; Mossay, C, 1981) |
"Studies using the guinea pig ileum bioassay technique have previously shown that patients with either asthma or chronic bronchitis have increased amounts of histamine in their sputum." | 3.66 | Histamine content of sputum from patients with asthma and chronic bronchitis. ( Bryant, DH; Pui, A, 1982) |
"The increased plasma-histamine levels observed after provocation of asthmatic subjects with antigen or exercise may result from the release of this granule-associated mediator from either mast cells or basophil leucocytes." | 3.66 | The role of basophils in asthma. I. Sodium cromoglycate on histamine release and content. ( Church, MK, 1982) |
"Investigational compounds active in anti-allergic/anti-asthmatic screens in rodents in vivo (IgE-mediated passive cutaneous anaphylaxis in rats, IgE-mediated anaphylactic bronchoconstriction in guinea pigs, and histamine-, or acetylcholine-induced bronchoconstriction in guinea pigs) were examined for their effects against IgE-mediated histamine release from human basophiles." | 3.66 | Comparison of effects of investigational compounds upon allergic phenomena in rodents in vivo and in human basophils in vitro. ( Magro, A; Mielens, ZE, 1982) |
"We studied the effects of continuous positive airway pressure (CPAP) in 8 asthmatic subjects in whom bronchospasm was induced by aerosolized histamine." | 3.66 | Effect of continuous positive airway pressure on respiratory mechanics and pattern of breathing in induced asthma. ( Engel, LA; Martin, JG; Shore, S, 1982) |
"The concomitant injection of isoproterenol with house dust allergen inhibited the immediate skin allergic reaction in asthmatic patients." | 3.66 | The inhibitory effect of isoproterenol and dibutyryl cyclic-AMP on the immediate skin reaction. ( Ishihara, M; Mue, S; Ohmi, T; Takahashi, M; Takishima, T; Tamura, G, 1982) |
"Eleven asthmatic subjects inhaled doubling concentrations of histamine until a near sixfold increase in total pulmonary flow resistance had been reached." | 3.66 | Time course of the bronchoconstriction induced by inhaled histamine and methacholine. ( Bégin, P; Cartier, A; Malo, JL; Martin, RR; Sestier, M, 1983) |
"The tussive and bronchoconstrictive effects of histamine inhalation in 7 normals, 7 asthmatics, and 24 patients with chronic cough (PCC) were measured by counting coughs during a standard histamine inhalation challenge." | 3.66 | Comparison of the tussive effects of histamine and methacholine in humans. ( Banner, AS; Chausow, AM, 1983) |
"The effects on airflow resistance of an inhaled H1 receptor antagonist, clemastine, and an H2 receptor antagonist, cimetidine, have been investigated in normal and asthmatic subjects." | 3.66 | Effect of inhaled H1 and H2 receptor antagonist in normal and asthmatic subjects. ( Kerr, JW; Thomson, NC, 1980) |
"In twelve subjects with perennial allergic rhinitis and stable asthma nasal obstruction was induced with histamine diphosphate solution introduced onto the nasal mucosa by a nasal atomizer in a cumulative manner starting with a 0." | 3.66 | The response of the airways to nasal stimulation in asthmatics with rhinitis. ( Salome, C; Yan, K, 1983) |
"In asthmatics, alpha-adrenergic blockage with oral phentolamine partially or completely blocked bronchospasm after maximal exercise challenge." | 3.66 | The effect of alpha adrenergic blockade on non-specific airways reactivity and exercise induced asthma. ( Bleecker, ER; Chahal, KS; Mason, P; Permutt, S, 1983) |
"In 18 clinically stable asthmatic patients histamine inhalation challenges were performed with a Wright's nebuliser and tidal volume breathing for two minutes on two to four occasions for each subject at a maximum interval of two weeks." | 3.66 | Histamine dose-response curves in asthma: reproducibility and sensitivity of different indices to assess response. ( Dehaut, P; Malo, JL; Martin, RR; Rachiele, A, 1983) |
"Two methods of interpreting histamine inhalation dose-response curves were compared in 27 normal and 41 asthmatic subjects." | 3.66 | Measurement of responsiveness to inhaled histamine using FEV1: comparison of PC20 and threshold. ( Berscheid, BA; Cockcroft, DW; Murdock, KY, 1983) |
"The histamine provocation concentration producing a 20% reduction in FEV1 (PC20-FEV1) and that producing a 35% reduction in SGaw (PC35-SGaw) were determined on two different days in 16 asthmatics and 27 normal subjects." | 3.66 | Measurement of responsiveness to inhaled histamine: comparison of FEV1 and SGaw. ( Berscheid, BA; Cockcroft, DW, 1983) |
"We studied regional changes in ventilation and aerosol deposition after histamine challenge in six patients with asthma and two with rhinitis and a history of wheezing." | 3.66 | Histamine bronchial challenge: effect on regional ventilation and aerosol deposition. ( Ahmad, D; Chamberlain, MJ; Clague, H; Morgan, WK; Vinitski, S, 1983) |
"Arterial plasma histamine concentrations were measured after exercise in 10 subjects with extrinsic atopic asthma, 10 who were non-atopic and non-asthmatic and seven who were atopic but non-asthmatic, by a single isotope radioenzymatic assay." | 3.66 | Plasma histamine in asthmatic and control subjects following exercise: influence of circulating basophils and different assay techniques. ( Davies, RJ; Moodley, I; Morgan, DJ; Phillips, MJ, 1983) |
"Beta adrenergic agents given by aerosol decrease the responsiveness of the airways to histamine and methacholine in subjects with asthma, causing a shift of the dose response curve to the right." | 3.66 | Effect of aerosol fenoterol on the severity of bronchial hyperreactivity in patients with asthma. ( Salome, CM; Schoeffel, RE; Woolcock, AJ; Yan, K, 1983) |
"In a previous study 30 asthmatic children with positive skin tests to cat dander, had bronchial challenge tests with histamine and antigen, quantitative skin tests with cat dander, and measurements of serum-specific IgE concentrations (first study)." | 3.66 | Variation with time in bronchial responsiveness to histamine and to specific allergen provocation. ( Kerrebijn, KF; Neijens, HJ, 1983) |
"Significant increase in the maximum post-exercise values of plasma histamine (PH), whole blood histamine (WBH) and neutrophil chemotactic factor (NCF) occurred in arterial blood within the first hour after exercise in asthmatic patients." | 3.66 | Histamine, neutrophil chemotactic factor and circulating basophil levels following exercise in asthmatic and control subjects. ( Davies, RJ; Elliott, EV; Moodley, I; Morgan, DJ; Phillips, MJ, 1982) |
" readiness for asthma in general (the crucial dosage of histamine able to induce asthma increases)." | 3.66 | Pharmacology of disodium cromoglycate. ( Altounyan, RE, 1980) |
" An analogous mechanism may account for aspirin-induced asthma in man." | 3.66 | Evidence for lipoxygenase pathway involvement in allergic tracheal contraction. ( Burka, JF; Paterson, NA, 1980) |
"A study to determine whether the bronchoconstriction induced by low concentration of sulfur dioxide in subjects with asthma decreases with repeated exposure was undertaken." | 3.66 | Tolerance to sulfur dioxide-induced bronchoconstriction in subjects with asthma. ( Bethel, RA; Boushey, HA; Epstein, J; Nadel, JA; Sheppard, D, 1983) |
"The influence of acetylsalicylic acid (ASA) on skin response to intradermal injection of compound 48/80 and histamine was studied in order to determine whether ASA elicits any abnormalities also in the skin of asthmatics reacting with bronchoconstriction to ingestion of this drug." | 3.66 | Potentiation by acetylsalicylic acid of skin weal response to compound 48/80 in ASA-sensitive asthmatics. ( Grzelewska-Rzymowska, I; Kowalski, ML; Rozniecki, J; Szmidt, M, 1983) |
"Standardized histamine provocations were repeated during remission on 10 atopic bronchial asthmatics, at 14 days (short-term) and after more than 12 months (long-term)." | 3.66 | Short-term and long-term variation in bronchial response to histamine in asthmatic patients. ( Lindholm, NB; Löwhagen, O, 1983) |
"Nine patients with extrinsic bronchial asthma were challenged with increasing doses of histamine until there was a 20% fall in the forced expiratory volume in one second (FEV1)." | 3.66 | Arterial oxygen changes in asthmatics following histamine. ( Chapman, TT, 1980) |
"To study the salivary response in asthma and periodontitis, calcium and phosphorus concentrations were determined from parotid and whole saliva." | 3.66 | Studies of immunologic and inflammatory factors in saliva in patients with asthma and in patients with periodontitis. ( Hyyppä, T, 1981) |
"Four workers from a recently established vanadium pentoxide refinery in Western Australia presented with green discoloration of the tongue, upper respiratory symptoms, and asthma." | 3.66 | Asthma caused by occupational exposure to vanadium compounds. ( Musk, AW; Tees, JG, 1982) |
"The authors studied variations in histamine and serotonin levels in whole blood, in ten asthmatics with bronchospasm induced by running." | 3.66 | [Histamine and serotonin levels in exercise induced bronchospasm in asthmatics (author's transl)]. ( Aubry, JP; Cheymol, G; Dry, J; Pradalier, A, 1980) |
"We have prospectively examined in 51 patients the relationship between the level of airway responsiveness to histamine and methacholine and the minimum medications required to control asthma." | 3.66 | Airway responsiveness to histamine and methacholine: relationship to minimum treatment to control symptoms of asthma. ( Frith, PA; Hargreave, FE; Juniper, EF, 1981) |
"In order to determine the effect of drugs on bronchial hyperreactivity in subjects with asthma, 12 atopic asthmatic volunteers underwent bronchial challenge with either histamine or methacholine on three separate days." | 3.66 | Effect of aerosol and oral fenoterol on histamine and methacholine challenge in asthmatic subjects. ( Salome, CM; Schoeffel, RE; Woolcock, AJ, 1981) |
" Venous plasma histamine and catecholamines were measured in stable asthmatic subjects by a recently developed specific and sensitive radioenzymatic assay." | 3.66 | Plasma histamine and catecholamines in stable asthmatic subjects. ( Barnes, PJ; Brown, MJ; Ind, PW, 1982) |
"Histamine inhalation provocation-tests were performed in twenty-two young asthmatics with normal lung-function tests with progressive, increasing doses of a pressurized aerosol of histamine phosphate." | 3.66 | Site of action of inhaled histamine in asymptomatic asthmatic patients. ( Bracamonte, M; de Coster, A; Scano, G; Sergysels, R; Stendardi, L, 1982) |
"Bronchial responsiveness to histamine was measured in 35 adult asthmatics whose symptoms were controlled on a minimum of medication." | 3.66 | Long-term stability of bronchial responsiveness to histamine. ( Frith, PA; Hargreave, FE; Juniper, EF, 1982) |
"The importance of histamine dose vs histamine concentration in determining the response to inhaled histamine was evaluated by comparing the effect of 30 sec and two min inhalation times on duplicate histamine inhalation tests in 15 asthmatic patients." | 3.66 | Standardization of inhalation provocation tests. Dose vs concentration of histamine. ( Berscheid, BA; Cockcroft, DW, 1982) |
"We examined the effects of pharmacologic antagonists on the bronchial response to inhaled histamine in 11 normal and 11 asthmatic subjects." | 3.66 | Histamine dose-response relationships in normal and asthmatic subjects. The importance of starting airway caliber. ( Chung, KF; Keyes, SJ; Morgan, B; Snashall, PD, 1982) |
"A standardized bronchial histamine challenge was performed in 423 patients presenting with 1) asthma, 2) rhinitis, 3) asthma and rhinitis 4) rhinitis with cough or 5) chronic cough alone." | 3.66 | Bronchial responsiveness to histamine and allergen in patients with asthma, rhinitis, cough. ( Stevens, WJ; Vermeire, PA, 1980) |
"Histamine inhalation tests were performed in 12 asthmatic patients using a 2-min tidal breathing inhalation technique." | 3.66 | Repeated histamine inhalation tests in asthmatic patients. ( Alpers, JH; Crockett, AJ; Hamilton, R; Ruffin, RE, 1981) |
"A C-11 substituted PGE2 analog, DHET-PGE2 [alpha-11-deoxy-11 alpha-(2-hydroxyethylthio)-PGE2 methyl ester], was demonstrated to exert potent bronchodilator activity in three in vivo models of augmented airway resistance: (1) acute bronchospasms, induced by 5-hydroxytryptamine, histamine and acetylcholine in the anesthetized guinea pig, (2) acute bronchospasm, induced by pilocarpine, in the anesthetized dog, and (3) chronic bronchospasm, induced by SO2 exposure, in the unanesthetized dog." | 3.66 | Bronchodilator activity of a PGE2 analog in animals and in man. ( Birkhead, NC; Birnbaum, JE; Dessy, F; Oronsky, AL; Rihoux, JP; VanHumbeeck, L, 1981) |
" Venous plasma histamine was measured by a specific and sensitive radioenzymatic assay in seven male extrinsic asthmatic and six age-matched non-atopic non-asthmatic male subjects during exercise and voluntary isocapnic hyperventilation." | 3.66 | Venous plasma histamine in exercise- and hyperventilation-induced asthma in man. ( Barnes, PJ; Brown, MJ, 1981) |
"Calcium antagonist, verapamil given by inhalation did not alter histamine bronchial hyper-reactivity in ten patients with extrinsic bronchial asthma and similarly did not modify methacholine-induced bronchoconstriction in further five patients." | 3.66 | The effect of verapamil on histamine and methacholine-induced bronchoconstriction. ( Patel, KR, 1981) |
"The aim of the present study was to determine if the measurement of the slope of teh histamine dose-response curve (bronchial reactivity) could provide useful information on the clinical state of asthma." | 3.66 | Histamine dose-response curves in asthma: relevance of the distinction between PC20 and reactivity in characterising clinical state. ( Beaupré, A; Malo, JL, 1981) |
"Although histamine plays an important role in the pathophysiology of asthma through stimulation of H1 receptors, H1 antagonists are of only limited use in this disease when given orally." | 3.66 | Modulation of histamine-induced bronchoconstriction with inhaled, oral, and intravenous clemastine in normal and asthmatic subjects. ( Hartmann, V; Holle, JP; Magnussen, H; Schüler, E, 1981) |
"The skin-vascular reactivity (SVR) to histamine and adrenaline was studied in 165 patients with bronchial asthma--87 with atopic, 38 with infectious-allergic and 40--with mixed." | 3.66 | [Skin vascular and bronchoreceptor reactivity study of bronchial asthma]. ( Kosturkov, G; Vŭlcheva, T, 1981) |
"In vitro preparations of trachea isolated from normal and asthmatic guinea pigs were used to measure their maximum contractile response to histamine challenge and to determine spontaneous relaxation of smooth muscle of the airway." | 3.66 | Effects of ketamine and halothane on normal and asthmatic smooth muscle of the airway in guinea pigs. ( Aldrete, JA; Cabanas, A; Souhrada, JF, 1980) |
"To determine whether mediators of immediate hypersensitivity played a role in the pathogenesis of exercise-induced asthma, we measured the concentration of histamine and neutrophil-chemotactic activity present in systemic arterial blood during thermal challenges in five asymptomatic asthmatics." | 3.66 | Evaluation of role played by mediators of immediate hypersensitivity in exercise-induced asthma. ( Deal, EC; Ingram, RH; McFadden, ER; Soter, NA; Wasserman, SI, 1980) |
"Tracheal smooth muscle (TSM) from an ovalbumin sensitized canine model of allergic asthma showed hypersensitivity and hyper-reactivity to histamine (H) when compared to that from littermate controls in vitro." | 3.66 | Histamine pharmacology in airway smooth muscle from a canine model of asthma. ( Antonissen, LA; Bergen, J; Kepron, W; Kroeger, EA; Mitchell, RW; Stephens, NL, 1980) |
"14C-histamine was administered intrabronchially to asthmatic patients and controls." | 3.66 | Metabolism of 14C-histamine given intrabronchially to asthmatic patients. ( Bergmark, J; Granerus, G; Löwhagen, O; Thiringer, G, 1980) |
"Seventeen children with recurrent croup, who had their last episode within the previous 12 months, were evaluated clinically by allergy skin tests, pulmonary function tests, and a histamine inhalation challengae." | 3.66 | Upper and lower airway hyperreactivity in recurrent croup. ( Landau, LI; Schnall, RP; Zach, MS, 1980) |
"In 15 asthmatic subjects, flow volume loops were recorded before and after quantitative nebulization of increasing concentration of histamine and allergen, until a threshold response (-delta FEV1 > 10%) was obtained." | 3.66 | Effect of an H1 blocker, chlorpheniramine, on inhalation tests with histamine and allergen in allergic asthma. ( Popa, VT, 1980) |
" Hyperinflation was provoked in two asthmatic and three normal subjects by progressively doubling doses of histamine." | 3.66 | Tonic inspiratory muscle activity as a cause of hyperinflation in histamine-induced asthma. ( Bryan, AC; Muller, N; Zamel, N, 1980) |
"In order to determine if there is a relationship among arterial histamine levels, state of disease activity, and the magnitude and site of obstruction in exercise-induced asthma, we recorded airway resistance, lung volumes, spirometry, and density dependence of maximum expiratory flow before and after an exercise challenge in 17 asymptomatic individuals." | 3.66 | Magnitude and site of airway response to exercise in asthmatics in relation to arterial histamine levels. ( Ingram, RH; McFadden, ER; Soter, NA, 1980) |
"Eight subjects with asthma underwent bronchial challenge with histamine and methacholine." | 3.66 | Comparison of bronchial reactivity to histamine and methacholine in asthmatics. ( Salome, CM; Schoeffel, RE; Woolcock, AJ, 1980) |
"The underlying biochemical and physiological changes responsible for remarkable airway hyperreactivity to histamine and other non-specific stimuli in asthmatics are poorly understood." | 3.66 | Is airway hyperactivity in asthma due to histamine H2-receptor deficiency? ( Chand, N, 1980) |
"The preventive effect of ketotifen, a new drug with anti-histaminic and antiallergic properties, on histamine-induced bronchoconstriction was studied by open assessment in twenty-four adult patients with extrinsic asthma." | 3.66 | Preventive effect of ketotifen, a new antiallergic agent, on histamine-induced bronchoconstriction in asthmatics. ( Mattson, K; Nikander-Hurme, R; Poppius, H, 1979) |
"The investigation of 10 patients with allergic asthma showed histamine levels of 79." | 3.66 | [Histamine levels in blood of patients with allergic bronchial asthma (author's transl)]. ( Koppermann, G; Morr, H, 1979) |
"The contents of histamine and cyclic nucleotides were studied in leukocytes before and after a bronchoprovocation test on patients with extrinsic asthma." | 3.66 | Changes in histamine and cyclic nucleotide levels after bronchoprovocation in patients with extrinsic asthma. ( Andersson, RG; Brundin, A; Lindgren, BR, 1978) |
"Histamine has been measured in whole blood and in the plasma of twenty-three subjects following exercise testing of seventeen asthmatics and six normal controls." | 3.66 | Blood histamine levels after exercise testing. ( Burge, PS; Cromwell, O; Harries, MG; O'Brien, I; Pepys, J, 1979) |
"Nine asthmatic patients with a mean age of 14 yr received bronchial challenges with histamine and methacholine." | 3.66 | Bronchial hyperreactivity to histamine and methacholine in asthmatic children after inhalation of SCH 1000 and chlorpheniramine maleate. ( Kattan, M; Levison, H; Orange, RP; Woenne, R, 1978) |
"Bronchial responsiveness to inhaled histamine and exercise was measured in 19 asthmatics." | 3.66 | Bronchial responsiveness to inhaled histamine and exercise. ( Anderton, RC; Cockcroft, DW; Cuff, MT; Frith, PA; Hargreave, FE; Jones, NL; Morse, JL, 1979) |
" Predictions for rehospitalization were based on the levels of airways hyperreactivity, indexed by inhalation challenges with histamine or methacholine, and levels of anxiety focused upon and concurrent with periods of asthmatic distress, indexed by Panic-Fear symptomatology." | 3.66 | Medical outcome in asthmatic patients: effects of airways hyperreactivity and symptom-focused anxiety. ( Dirks, JF; Kinsman, RA; Spector, SL; Staudenmayer, H; Wangaard, C, 1979) |
"Levels of airways hyperreactivity, as indexed by methacholine and histamine thresholds, were determined for hospitalized asthmatic patients using the serial concentration, constant-breath method." | 3.66 | Methacholine and histamine inhalation challenges in asthma: relationships to age of onset, length of illness, and pulmonary functions. ( Fukuhara, J; Kinsman, RA; Spector, SL; Staudenmayer, H; Westmoreland, C, 1979) |
"Bronchial inhalation challenges to histamine, methacholine, and at least one antigen were performed on 183 asthmatic patients who previously had received skin tests to at least 16 different antigens." | 3.66 | Relationship between airways response to allergens and nonspecific bronchial reactivity. ( Horton, DJ; Kinsman, RA; Nathan, RA; Spector, SL, 1979) |
"Histamine metabolism was investigated in patients with intrinsic asthma, during the acute phase and in remission, by determination of the urinary excretion of histamine metabolites." | 3.66 | Studies on histamine metabolism in intrinsic bronchial asthma. ( Granerus, G; Löwhagen, O; Wetterqvist, H, 1979) |
"Fifty asthmatic children were tested with both a standardized treadmill exercise and a histamine inhalation on 2 separate days." | 3.66 | Comparative study of histamine and exercise challenges in asthmatic children. ( Kattan, M; Keens, TG; Levison, H; Mellis, CM, 1978) |
"In order to examine the hypothesis that bronchial reactivity to non-specific constrictor stimuli is influenced by the resting tone of the bronchial smooth muscle, the airway responses to inhaled histamine solution and inhaled isoprenaline were measured in 19 patients with airway obstruction." | 3.66 | Bronchial responsiveness to inhaled histamine and isoprenaline in patients with airway obstruction. ( Benson, MK, 1978) |
"The inert gas infusion technique was used to recover distributions of ventilation-perfusion ratios in anesthetized dogs during 17 episodes of acute asthma produced experimentally by broncho-provocation with aerosolized Ascaris suum extract, methacholine, or histamine." | 3.66 | Gas exchange during acute experimental canine asthma. ( Rubinfeld, AR; Wagner, PD; West, JB, 1978) |
"Investigation of magnesium, blood histamine level and eosinophilia were carried out on 28 bronchial asthma patients during the exacerbation of asthma and in asymptomatic period of the disease." | 3.66 | The relation between magnesium, blood histamine level and eosinophilia in the acute stage of the allergic reactions in humans. ( Chyrek-Borowska, S; Hofman, J; Obrzut, D, 1978) |
"The blood histamine level was determined in 66 patients with bronchial asthma and 25 guinea-pigs in whom the asthma attacks were induced by histamine or ovoalbumin inhalation after previous immunization of the animals." | 3.66 | Blood histamine level and histamine content in the lung tissue in immediate immunological reactions in human and experimental animals. ( Bortkiewicz, J; Chyrek-Borowska, S; Hofman, J; Szymański, W, 1978) |
"In five groups of children: representative sample of normal population, children suffering from bronchitis in the past and children with diagnosed asthmatics, results of unspecific bronchial reactivity to histamine were evaluated and in some of the groups results of skin and inhalatory reactions to allergen solutions were compared." | 3.66 | Importance of respiratory allergy in provoking reversible bronchial obstruction. ( Brański, H; Hałuszka, J; Sciślicki, A, 1978) |
"Controlled standardised histamine inhalation tests were carried out in 21 asthmatics to determine the degree of non-specific bronchial hyperreactivity with and without prior treatment with several anti-asthmatic drugs." | 3.65 | Protective effect of drugs on histamine-induced asthma. ( Cockcroft, DW; Hargreave, FE; Killian, DN; Mellon, JJ, 1977) |
"A simple device for measuring ventilatory function, the airflowmeter, was found to be at least as sensitive as the Wright peak-flow meter in detecting histamine-induced bronchoconstriction in asthmatic patients." | 3.65 | Use of a new simple device, the airflometer, in detecting changes in airways obstuction. ( Mattson, K; Poppius, H, 1977) |
"The respiratory threshold to histamine and the plasma cyclic adenosine monophosphate (AMP) every 5 min for 40 min after subcutaneous epinephrine were determined in 21 children with moderate bronchial asthma who were without symptoms at the time of study." | 3.65 | Correlation between increased bronchial responsiveness to histamine and diminished plasma cyclic adenosine monophosphate response after epinephrine in asthmatic children. Diminished plasma cyclic adenosine monophosphate response after epinephrine in moder ( Aksnes, L; Apold, J, 1977) |
"Increased bronchial sensitivity to inhaled histamine in asthma is well known." | 3.65 | Decreased H2 histamine response of granulocytes of asthmatic patients. ( Busse, WW; Sosman, J, 1977) |
" Cromolyn sodium aerosols prevented 48/80 induced asthma but did not influence histamine induced broncho-constriction." | 3.65 | Effect of cromolyn sodium and of daily exposure to compound 48/80 on experimental asthma. ( Ambrus, LC; Thurber, L, 1975) |
"Histamine is thought to be one of the primary mediators of the airways response in allergic asthma." | 3.65 | Effects of intravenous histamine on pulmonary mechanics in nonasthmatic and asthmatic subjects. ( Brown, R; Ingram, RH; McFadden, ER; Wellman, JJ, 1977) |
"Lack of in vivo data on blood histamine changes in subjects during induced attacks of asthma prompted serial determinations of blood histamine levels and of the forced expiratory volume of the first second (FEV1) in 2 asthmatic undergoing antigen (house dust) inhalation challenge and in 3 subjected to methacholine inhalation." | 3.65 | Opposite changes in blood histamine and force expiratory volume during bronchial inhalation challenge. ( Haust, HL; McCourtie, DR; Poon, HC, 1977) |
"Bronchial reactivity to prostaglandins F2alpha (PGF2alpha), E2 (PGE2) and histamine has been studied in 27 patients with aspirin-sensitive asthma and in 28 asthmatics without this sensitivity." | 3.65 | Bronchial reactivity to prostaglandins F2alpha, E2, and histamine in different types of asthma. ( Nizankowska, E; Nizankowski, R; Szczeklik, A, 1977) |
"Under carefully controlled conditions, seven aspirin-intolerant asthmatic patients were challenged with oral aspirin and experienced respiratory tract reactions with a decline in forced expiratory volume in 1 sec (FEV1) ranging from 26 to 64%." | 3.65 | Oral aspirin challenges in asthmatic patients: a study of plasma histamine. ( Arroyave, CM; Bhat, KN; Stevenson, DD; Tan, EM, 1976) |
"Plasma, whole blood, and urinary histamine levels have been determined in 64 normal subjects, in 10 patients with severe asthma, and in 10 control patients with other illnesses." | 3.65 | Histamine levels in plasma, blood, and urine in severe asthma, and the effect of corticosteroid treatment. ( Bruce, C; Seaton, A; Taylor, WH; Weatherstone, R, 1976) |
"In order to examine the protective effect of allopurinol on experimental asthma produced by histamine aerosol in guinea pigs, allopurinol was administered intraperitoneally resulting in a significant prolongation of survival times." | 3.65 | Protective effect of allopurinol on bronchiolar constriction induced by histamine. ( Akaoka, I; Nishida, Y; Nishizawa, T, 1976) |
" In a group of asthmatics, intravenous histamine induced a significant decrease in the forced vital capacity, expiratory volume in the first second, and peak flow, while increasing the respiratory system resistance and the closing volume." | 3.65 | The unreliability of the maximal midexpiratory flow as an index of acute airway changes. ( Newball, HH, 1975) |
"Bronchial provocation tests using aerosolized serially diluted histamine and methacholine were given to nearly 200 asthmatics." | 3.65 | A comparison of methacholine and histamine inhalations in asthmatics. ( Farr, RS; Spector, SL, 1975) |
"The absolute counts on basophil and eosinophil leucocytes, percentage of vacuolated eosinophil cells and whole blood histamine were determined in 30 controls and 34 patients with bronchial asthma." | 3.65 | Cytomorphological variations and blood histamine in bronchial asthma. ( Baldwa, VS; Chopra, YM; Goyal, RK; Sehgal, PP; Singh, J; Varandani, N, 1976) |
" In guinea-pigs, pretreatment with these agents increases asthma mortality provoked by histamine which suggests that this resistance may reduce the effectiveness of endogenous sympathetic drive to the bronchi." | 3.65 | Resistance to -adrenoceptor stimulants (a possible explanation for the rise in ashtma deaths). ( Conolly, ME; Davies, DS; Dollery, CT; George, CF, 1971) |
"Inhalation of aerosols of citric acid, histamine phosphate, or carbon dust, or air cooled to - 20 degrees C or rapid respiratory maneuvers (inspiration or expiration) results in an increase in airway resistance in some patients with asthma or bronchitis." | 3.64 | Role of autonomic nervous system and the cough reflex in the increased responsiveness of airways in patients with obstructive airway disease. ( Jacobs, FM; Nadel, JA; Simonsson, BG, 1967) |
"The tissues affected by histamine and anaphylactic reactions are identical." | 3.63 | Histamine and the antihistaminic drugs. ( KEENEY, EL, 1950) |
" Extrapolation of the log dose-response curve was undertaken to calculate the concentration (provocation concentration, PC) causing an increase airways resistance of 20, 40, 60, 80, 100, 120, 140 and 160% (RInt PC1." | 2.80 | Airways resistance in bronchial challenge testing. ( Baxter, MA; Coates, D; Wilson, AM, 2015) |
"Histamine challenges were performed prior to (day -7) and after inoculation (day 3), and were expressed as provocative concentration causing a 20% fall in forced expiratory volume in one second (FEV1) (PC20)." | 2.69 | Relationship between exhaled nitric oxide and airway hyperresponsiveness following experimental rhinovirus infection in asthmatic subjects. ( de Gouw, HW; Dick, EC; Grünberg, K; Kroes, AC; Schot, R; Sterk, PJ, 1998) |
"Histamine challenges were carried out by tidal breathing method at entry, and at Days 4, 8, 22, 36, and 40." | 2.69 | Effects of theophylline on tolerance to the bronchoprotective actions of salmeterol in asthmatics in vivo. ( Cheung, D; de GOEIJ, JA; de GRAAFF, CS; Steen, H; Sterk, PJ; Wever, AM, 1998) |
"Seratrodast did not suppress IAR or LAR." | 2.69 | Effects of cysteinyl-leukotriene receptor antagonist, thromboxane A2 receptor antagonist, and thromboxane A2 synthetase inhibitor on antigen-induced bronchoconstriction in patients with asthma. ( Asai, S; Kohno, S; Matsuo, N; Matsuse, H; Obase, Y; Shimoda, T, 1998) |
"Pathogenesis of non-atopic bronchial asthma remains still an open question." | 2.69 | [Bronchial hyperreactivity to histamine and levels of serum eosinophil cationic protein in patients with non-atopic asthma]. ( Dobek, R; Liebhart, E; Litwa, M; Małolepszy, J; Medrala, W; Wolańczyk-Medrala, A; Wrzyszcz, M; Wytrychowski, K, 1999) |
" A histamine challenge test was done 12 h after the last dose of each treatment period, and dose-response curves to inhaled salbutamol (200-3200 micrograms) were constructed 36 h after the last dose." | 2.68 | Bronchodilator subsensitivity to salbutamol after twice daily salmeterol in asthmatic patients. ( Grove, A; Lipworth, BJ, 1995) |
" In each subject, dose-response curves for the effects on forced expiratory volume in one second (FEV1) of serially doubling doses of inhaled histamine were obtained on three different days, 15 min after pretreatment with either methoxamine (10 mg) or duplicated placebo." | 2.68 | Effects of pretreatment with inhaled methoxamine on bronchial responses to histamine in asthmatic subjects. ( Dall'Ava-Santucci, J; Dinh-Xuan, AT; Lockhart, A; Monchi, M; Phan-Puibaraud, TT; Regnard, J, 1995) |
"Atopic dermatitis and bronchial asthma are genetically dependent diseases, connected with an over-synthesis of IgE antibodies, in which a chronic inflammation is characteristic for their pathogenesis." | 2.68 | [Pulmonary function tests and bronchial reactiveness with histamine in patients with atopic dermatitis and bronchial asthma]. ( Faber, M; Jahnz-Rózyk, K; Paluchowska, E; Samochocki, Z, 1996) |
" The PD20 (dose of histamine causing a 20% fall in FEV1) was measured before and 11, 35, and 59 h after cessation of treatment and a bronchodilator dose-response study before and 83 h after cessation of treatment." | 2.67 | Asthma control during and after cessation of regular beta 2-agonist treatment. ( Pavord, ID; Tattersfield, AE; Wahedna, I; Wisniewski, AF; Wong, CS, 1993) |
"With histamine in seven BDP-treated and in five placebo-treated patients, decrease in FEV1 > or = 20 percent from saline solution was paralleled by a significant decrease in tidal volume (VT), inspiratory time (Ti), and expiratory time (Te), and increase in respiratory frequency (RF)." | 2.67 | Preventive effects of beclomethasone on histamine-induced changes in breathing pattern in asthma. ( Duranti, R; Fanelli, A; Gorini, M; Maggi, E; Scano, G; Stendardi, L, 1993) |
" The dose-response curves for change in PC20 indicated that the higher doses of the nebulizer solution delivered more drug to beta 2 receptors in the lung than the lower doses from the MDI." | 2.67 | Relative amount of albuterol delivered to lung receptors from a metered-dose inhaler and nebulizer solution. Bioassay by histamine bronchoprovocation. ( Blake, KV; Harman, E; Hendeles, L; Hoppe, M, 1992) |
"Systemic inflammation was investigated by sequential blood determinations of total (and differential) white cells, complement anaphylatoxin C5a, interleukin-6 (IL-6), tumor necrosis factor alpha (TNF-alpha), and C-reactive protein (CRP)." | 2.67 | Inflammatory response to acute inhalation of endotoxin in asthmatic patients. ( Content, J; Duchateau, J; Ginanni, R; Le Bon, B; Michel, O; Sergysels, R, 1992) |
" Both the provocative dose to cause a 20 percent decline in the FEV1 (PD20 FEV1) and the slope of the dose-response curve were not significantly different between the standard protocol and either of the two abbreviated protocols." | 2.67 | Is an abbreviated bronchial challenge with histamine valid? ( Schmidt, LE; Schwartz, DA; Thorne, PS; Watt, JL, 1992) |
"Histamine challenges were performed before, at approximately 2 h (or after resolution of the immediate bronchial response [IR]), and 24 h after saline solution or Ag inhalation." | 2.67 | The relationship between airway responsiveness measured before and after the allergen-induced late asthmatic response. ( Bernstein, DI; Bernstein, IL; Mittman, RJ; Piyamahunt, A; Ploysongsang, Y, 1992) |
" To determine whether these drugs also protect against excessive airway narrowing, the effect of inhaled salbutamol on the position and shape of the dose-response curves for histamine or methacholine was investigated in 12 patients with asthma and 11 with chronic obstructive lung disease." | 2.67 | The protective effect of a beta 2 agonist against excessive airway narrowing in response to bronchoconstrictor stimuli in asthma and chronic obstructive lung disease. ( Bel, EH; Dijkman, JH; Sterk, PJ; Timmers, MC; Zwinderman, AH, 1991) |
"PC20 histamine was assessed on the 3 consecutive days before starting the trial, on the last day of medication, 3 days later, and once a week thereafter until PC20 returned to baseline." | 2.67 | Duration of the effect of astemizole on histamine-inhalation tests. ( Cartier, A; Fu, CL; Ghezzo, H; L'Archevêque, J; Malo, JL, 1990) |
" The provocative concentration causing a 20% fall in FEV1 (logPC20) was calculated by linear interpolation of log dose-response curves." | 2.67 | Effect of inhaled furosemide and bumetanide on adenosine 5'-monophosphate- and sodium metabisulfite-induced bronchoconstriction in asthmatic subjects. ( Barnes, PJ; Chen-Worsdell, YM; Chung, KF; Fuller, RW; O'Connor, BJ, 1991) |
" The distribution of the bronchial responsiveness was described as (1) the provoking concentration that causes a 20% reduction in FEV1 (2) the dose-response slope (DRS), that is, the linear slope of the dose-response curve, and (3) reduction in FEV1 after 6 minutes of exercise on a treadmill." | 2.67 | The distribution of bronchial responsiveness to histamine and exercise in 527 children and adolescents. ( Bach-Mortensen, N; Backer, V; Dirksen, A; Hansen, KK; Laursen, EM; Wendelboe, D, 1991) |
"3." | 2.67 | Effect of sodium-transport inhibitors on bronchial reactivity in vivo. ( Britton, JR; Knox, AJ; Tattersfield, AE, 1990) |
" Airway response was measured as FEV1 and the dose of substance P (using a dose range of 23-736 nmol) producing a 20% decrease in FEV1 (PD20) was calculated from the individual semilogarithmic dose-response curves." | 2.66 | Effect of nedocromil on bronchospasm induced by inhalation of substance P in asthmatic subjects. ( Crimi, N; Mistretta, A; Oliveri, R; Palermo, B; Palermo, F; Polosa, R; Vancheri, C, 1988) |
"Thirteen children with perennial bronchial asthma, with a mean age of 11." | 2.66 | Ipratropium bromide (Atrovent) in childhood asthma: a cumulative dose-response study. ( Friberg, S; Graff-Lonnevig, V, 1989) |
" This was conducted, first as a dose-response study and, second, as a time-course study." | 2.66 | Inhibition of hypertonic saline-induced bronchoconstriction by terfenadine and flurbiprofen. Evidence for the predominant role of histamine. ( Finnerty, JP; Holgate, ST; Wilmot, C, 1989) |
"Terfenadine (Seldane) is a new, highly potent H1 histamine receptor antagonist that in clinically effective doses is free of side effects." | 2.66 | Terfenadine (Seldane) is a potent and selective histamine H1 receptor antagonist in asthmatic airways. ( Holgate, ST; Rafferty, P, 1987) |
"In 12 patients with bronchial asthma we performed histamine bronchial challenges before and four hours after ingestion of placebo, 2." | 2.66 | The inhibitory effect of azelastine and ketotifen on histamine-induced bronchoconstriction in asthmatic patients. ( Magnussen, H, 1987) |
"Azelastine did not inhibit the effect of inhaled LTC4; the geometric mean PD20FEV1 LTC4 (nmol) after a single dose and 14 days' treatment was 0." | 2.66 | Effect of azelastine on bronchoconstriction induced by histamine and leukotriene C4 in patients with extrinsic asthma. ( Albazzaz, MK; Patel, KR, 1988) |
"Pretreatment with albuterol abolished any significant bronchoconstriction, with mean maximal falls in SGaw and FEV1 after challenge of 7." | 2.66 | Influence of albuterol, cromolyn sodium and ipratropium bromide on the airway and circulating mediator responses to allergen bronchial provocation in asthma. ( Church, MK; Durham, SR; Holgate, ST; Howarth, PH; Kay, AB; Lee, TH, 1985) |
"Histamine PD20 FEV1 was assessed 4 h after the administration of salbutamol 200 micrograms, a combination of fenoterol 200 micrograms and ipratropium bromide 80 micrograms, and placebo." | 2.66 | Histamine-induced bronchial response after administration of placebo, salbutamol and a combination of a beta-2-adrenergic drug (fenoterol) with an anticholinergic agent (ipratropium bromide) in asymptomatic asthma patients. ( Cresci, F; Fontana, G; Mugnai, M; Panuccio, P, 1986) |
"Histamine levels were noted to rise in patients who had a dual response of a mild to moderate nature, but did not change in patients who had severe asthma." | 2.66 | Role of chemical mediators after antigen and exercise challenge in children with asthma. ( Akazawa, A; Akimoto, K; Iikura, Y; Kisida, M; Kondou, T; Nagakura, T; Odajima, Y; Okuma, M; Walsh, GM; Yukishita, T, 1988) |
" Airway responsiveness thus appears to be a useful tool for evaluating inhaled beta 2-agonists and designing beta 2-agonist dosing regimens." | 2.66 | Use of bronchial provocation with histamine to compare the pharmacodynamics of inhaled albuterol and metaproterenol in patients with asthma. ( Ahrens, RC; Annis, L; Harris, JB; Milavetz, G; Ries, R, 1987) |
" The dose-response curves were compared by an analysis of variance." | 2.66 | Effects of clonidine on bronchial responses to histamine in normal and asthmatic subjects. ( Advenier, C; Dinh Xuan, AT; Lockhart, A; Mantrand, P; Matran, R; Regnard, J, 1988) |
"Histamine was inhaled in the following concentrations: 0." | 2.66 | Reproducibility of early asthmatic response to Cladosporium herbarum. ( Boudet, L; Bundgaard, A, 1986) |
"Histamine was inhaled at concentrations of 0." | 2.66 | Reproducibility of the late asthmatic response. ( Boudet, L; Bundgaard, A, 1986) |
"Verapamil was chosen because of its aqueous solubility and hence suitability for aerosol administration in higher doses than previously given." | 2.66 | Effects of the calcium channel blocker, verapamil, on asthmatic airway responses to muscarinic, histaminergic, and allergenic stimuli. ( Fish, JE; Norman, PS, 1986) |
"The presence of gastro-oesophageal reflux was investigated in 18 children with moderate to severe asthma by overnight oesophageal pH monitoring." | 2.66 | Gastro-oesophageal reflux and childhood asthma: the acid test. ( Charette, L; Silverman, M; Thomson, AH; Wilson, NM, 1985) |
"3 Histamine provocation was repeated 2 h after administration of placebo, propranolol 40 mg, pindolol 5 mg or metoprolol 50 mg." | 2.65 | Influence of intrinsic sympathomimetic activity (ISA) during beta-adrenoceptor blockade in asthmatics. ( Dorow, P, 1982) |
"To determine whether treatment with atropine causes dose-dependent inhibition of histamine-induced bronchoconstriction, we constructed dose-response curves to inhaled histamine after inhalation of placebo and 0." | 2.65 | Variable inhibition of histamine-induced bronchoconstriction by atropine in subjects with asthma. ( Bethel, RA; Boushey, HA; Epstein, J; Nadel, JA; Sheppard, D; Skoogh, BE, 1984) |
"Histamine challenge is a satisfactory method of assessing the proective effect of a drug in asthmatic children." | 2.65 | Protective effect of inhaled salbutamol powder in children assessed by histamine challenge. ( Martin, AJ; Pullan, CR, 1980) |
"Nifedipine is a potent antagonist of calcium ion influx in smooth muscle and secretory cells, and these studies suggest that it may inhibit release of mast cell mediators and reduce bronchial smooth muscle contractility in asthma." | 2.65 | A calcium antagonist, nifedipine, modifies exercise-induced asthma. ( Barnes, PJ; Brown, MJ; Wilson, NM, 1981) |
"A series of 191 patients with bronchial asthma were treated with menaquinone for not less than one year to investigate the clinical effects of the drug." | 2.64 | Menaquinone (vitamin K2) therapy for bronchial asthma. II. Clinical effect of menaquinone on bronchial asthma. ( Kimur, I; Saito, K; Sato, S; Takahashi, K; Tanizaki, Y, 1975) |
" Sodium cromoglycate in a dosage of 800 mg a day for 1 week, or a single dose of 1." | 2.64 | Effects of orally administered sodium cromoglycate in asthma and urticaria due to foods. ( Burge, PS; Harries, MG; O'Brien, IM; Pepys, J, 1978) |
"Twenty patients with extrinsic type bronchial asthma are shown to have a significant fall in vital capacity (V." | 2.63 | Effect of alpha-receptor blocking drugs and disodium cromoglyate on histamine hypersensitivity in bronchial asthma. ( Govindaraj, M; Kerr, JW; Patel, KR, 1970) |
"Histamine is a biogenic amine with extensive effects on many immune cell types." | 2.55 | Immune regulation by histamine and histamine-secreting bacteria. ( Akdis, CA; Barcik, W; O'Mahony, L; Wawrzyniak, M, 2017) |
"In the allergic bronchial asthma model using HDC-KO mice it was found that histamine positively controls eosinophilia, but not bronchial hypersensitivity." | 2.46 | Histamine synthesis and lessons learned from histidine decarboxylase deficient mice. ( Ohtsu, H, 2010) |
"Histamine is a ubiquitous inflammatory mediator intimately associated with the pathology of allergy." | 2.46 | The role of histamine in asthma. ( Dunford, PJ; Holgate, ST, 2010) |
"Histamine also plays a role in inducing atherosclerosis in the mouse model." | 2.44 | Progress in allergy signal research on mast cells: the role of histamine in immunological and cardiovascular disease and the transporting system of histamine in the cell. ( Ohtsu, H, 2008) |
"Histamine plays an important role in the pathogenesis of atopic asthma through differential regulation of T helper lymphocytes." | 2.42 | Effects of histamine on Th1/Th2 cytokine balance. ( Khan, MM; Packard, KA, 2003) |
"Histamine is a potent vasoactive agent, bronchial smooth muscle constrictor, and stimulant of nociceptive itch nerves." | 2.41 | Histamine in health and disease. ( Baraniuk, JN; Repka-Ramirez, MS, 2002) |
"Histamine is an important mast cell- and basophil-derived mediator that has been implicated in the pathogenesis of asthma, resulting in smooth muscle contraction, mucus hypersecretion, and increased vascular permeability leading to mucosal edema." | 2.41 | Second-generation antihistamines in asthma therapy: is there a protective effect? ( Walsh, GM, 2002) |
" Results are most usefully expressed as the provocative dose producing a 20% fall in FEV1 (PD20FEV1) or the dose-response slope (DRS)." | 2.40 | Testing airway responsiveness using inhaled methacholine or histamine. ( James, A; Ryan, G, 1997) |
" It remains unclear whether there is a dose-response relationship between inhaled corticosteroids and effect on bronchial hyperresponsiveness." | 2.40 | Effect of inhaled corticosteroids on bronchial responsiveness in patients with "corticosteroid naive" mild asthma: a meta-analysis. ( Akkermans, RP; Molema, J; van Grunsven, PM; van Schayck, CP; van Weel, C, 1999) |
"Histamine is an important mediator released from activated mast cells in acute bronchoconstriction provoked by allergen, exercise, hypertonic stimuli and inhaled adenosine." | 2.40 | Experimental models in asthma. ( Holgate, ST, 1999) |
" The most currently used bronchial provocation tests are those with nebulisation of histamine or methacholine either a tidal volume or from a dosimeter, a dose-response curve being obtained in measuring expiratory flows or airway resistance." | 2.39 | [Non-allergenic bronchial hyperreactivity. Measurement methods and reproducibility]. ( Boulet, LP; Denjean, A, 1994) |
" Function testing of bronchial responsiveness consists of 2 major parts : 1) standard method of acetylcholine or histamine inhalation test 2) direct-writing recorder of the dose-response curves of the airway to methacholine test (Astograph)." | 2.39 | [Function testing of bronchial responsiveness]. ( Fukuoka, M; Kubo, H; Nakajima, S; Tohda, Y, 1996) |
"Bronchial asthma is characterized by airways inflammation and airways hyperresponsiveness." | 2.38 | Sulphidopeptide leukotrienes in asthma. ( Arm, JP; Christie, P; Crea, AE; Hawksworth, RJ; Jacques, C; Lee, TH; O'Hickey, SP; Spur, BW, 1991) |
"Bronchial asthma is a unique disease; knowledge of the pathophysiology increases rapidly and underlines that is more a syndrome than a disease." | 2.38 | [Physiopathology of asthma]. ( Bousquet, J; Chanez, P; Clauzel, AM; Godard, P; Michel, FB; Pujol, JL, 1989) |
"Celiprolol has no influence on the adenylyl cyclase activity of the dog heart." | 2.37 | [Intrinsic sympathomimetic action and its special features as demonstrated by the beta-1-receptor blocker celiprolol]. ( Pittner, H, 1985) |
"Histamine has been found to activate three subtypes of receptors: the H1 subtype, which mediates a number of cellular events resulting in airway obstruction; the H2 subtype, which plays an unclear and perhaps variable role in mediating airway caliber changes; and the newly described H3 subtype, which has not yet been studied in relation to airway caliber." | 2.37 | Histamine and airway caliber. ( Casale, TB; Joad, J, 1988) |
"Environmental lung injury may take the form of acute tracheobronchitis, asthma, pulmonary edema, chronic bronchitis, emphysema, allergic pneumonitis, fibrosing alveolitis, pleurisy, and neoplastic disease." | 2.36 | Environmental injury of the lung: role of humoral mediators. ( Said, SI, 1978) |
"Amitriptyline is a drug of high potential, which inhibits acute bronchoconstriction and induces bronchodilatation in pre-contracted airways." | 1.91 | Amitriptyline inhibits bronchoconstriction and directly promotes dilatation of the airways. ( Böll, S; Braunschweig, T; Hempel, P; Klein, V; Martin, C; Michely, A; Rieg, AD; Spillner, J; Tenbrock, K; Verjans, E; von Stillfried, S; Wagner, N, 2023) |
"Bronchial asthma is a chronic lung disorder, that affects an estimated 262 million people worldwide, thereby, causing a large socio-economic burden." | 1.72 | Orally administered solasodine, a steroidal glycoalkaloid, suppresses ovalbumin-induced exaggerated Th2-immune response in rat model of bronchial asthma. ( Arora, P; Chellappan, DK; Dua, K; Gupta, G; Nainwal, LM; Oliver, BG; Singh, SK, 2022) |
"Scoring of lung inflammation was performed to observe pathological changes in response to SBP treatment compared to OVA/Alum." | 1.72 | ( Han, BK; Huang, WY; Jeong, I; Kim, JK; Kim, MJ; Kim, YJ; Lee, SH; Oh, SJ; Pan, JH; Shin, EC; Yoon, H, 2022) |
"Histamine is a critical inflammatory mediator in allergic diseases." | 1.62 | Targeted inhibition of allergen-induced histamine production by neutrophils. ( Alcañiz, L; Bellido, V; Chacón, P; Cornejo-García, JA; Del Valle Rodríguez, A; Doukkali, B; Monteseirín, J; Palacios, R; Puente, Y; Rivas-Pérez, D; Rodríguez, D; Vega-Rioja, A, 2021) |
"Histamine concentration was measured by high-performance liquid chromatography-fluorometry." | 1.48 | Nigella sativa as an anti-inflammatory agent in asthma. ( Hiedayati, N; Ikhsan, M; Maeyama, K; Nurwidya, F, 2018) |
" However, the EH method is limited in providing an objective and qualitative assessment of histamine pharmacodynamic response." | 1.43 | Population pharmacokinetic/pharmacodynamic modeling of histamine response measured by histamine iontophoresis laser Doppler. ( Jones, BL; Liu, X; Roberts, JK; Sherwin, CM, 2016) |
"Airway responsiveness to histamine, assessed as a dose-response slope (DRS), and a respiratory questionnaire were completed at 1, 6 and 12 months and 6, 11 and 18 years of age." | 1.42 | Longitudinal assessment of airway responsiveness from 1 month to 18 years in the PIAF birth cohort. ( Cox, DW; Goldblatt, J; Hayden, CM; Landau, LI; Le Souëf, PN; Mullane, D; Turner, SW; Zhang, GC, 2015) |
"Its use in bronchial asthma was reported in 1947." | 1.40 | Chromones. ( Edwards, AM, 2014) |
"The main objective of this study was to develop a novel aerosolized liposome formulation for pulmonary delivery of anti-asthmatic medication and to explore the relationship between the bioavailability and anti-asthmatic efficacy of such a formulation." | 1.38 | Liposomes prolong the therapeutic effect of anti-asthmatic medication via pulmonary delivery. ( Chen, X; Huang, W; Wong, BC; Wong, YF; Xu, M; Yang, Z; Yin, L, 2012) |
"Histamine is an important biogenic amine, which acts with a group of four G-protein coupled receptors (GPCRs), namely H(1) to H(4) (H(1)R - H(4)R) receptors." | 1.37 | Molecular modeling and QSAR studies of a set of indole and benzimidazole derivatives as H₄ receptor antagonists. ( Brandt, CA; Fernandes, JP; Ferreira, EI; Pasqualoto, KF, 2011) |
"Histamine intolerance is a clinically heterogeneous disease." | 1.36 | [Histamine intolerance mimics anorexia nervosa]. ( Herbst, RA; Peters, KP; Stolze, I, 2010) |
" The four diterpene acids dosed at 25 approximately 100 mg/kg had dose-dependently anti-asthmatic effects: 7-oxo-sandaracopimaric acid > 17-hydroxy-ent-kaur-15-en-19-oic acid > kaurenoic acid > hederagenin." | 1.36 | Inhibitory effects of diterpene acids from root of Aralia cordata on IgE-mediated asthma in guinea pigs. ( Cho, JH; Kim, CJ; Lee, JY; Sim, SS; Whang, WK, 2010) |
"We report a woman with bronchial asthma, who experienced two episodes of Matsutake-induced anaphylaxis." | 1.36 | A case of anaphylactic reaction following matsutake mushroom ingestion: demonstration of histamine release reaction of basophils. ( Nagase, H; Nakase, Y; Ohta, K; Sugimoto, N; Suzukawa, M; Toda, T; Yamaguchi, M, 2010) |
"Histamine has an important role in regulation of immune response which is mediated by differential expression of four distinct receptors, H1R-H4R." | 1.34 | Histamine 4 receptor activation induces recruitment of FoxP3+ T cells and inhibits allergic asthma in a murine model. ( Center, DM; Cross, L; Cruikshank, WW; Green, DS; Kornfeld, H; McAllister, B; Morgan, RK, 2007) |
"Adenosine plasma levels were significantly higher in sensitized than normal animals." | 1.34 | In vivo adenosine A(2B) receptor desensitization in guinea-pig airway smooth muscle: implications for asthma. ( Adinolfi, B; Blandizzi, C; Breschi, MC; Calderone, V; Camici, M; Fogli, S; Martinelli, C; Martinotti, E; Nieri, P, 2007) |
"Histamine plays an important role in the allergic inflammation." | 1.33 | No association of histamine- N-methyltransferase polymorphism with asthma or bronchial hyperresponsiveness in two German pediatric populations. ( Deichmann, K; Deindl, P; Heinzmann, A; Lau, S; Müller, S; Nickel, R; Niggemann, B; Peri-Jerkan, S; Sengler, C; Sommerfeld, C; Wahn, U, 2005) |
" In a longitudinal study, data were collected on atopy and lower respiratory tract illness (LRTI) in infancy, and AR (expressed as dose-response slope (DRS)), atopy, tobacco-smoke exposure and PDA in childhood." | 1.33 | Determinants of airway responsiveness to histamine in children. ( Gibson, NA; Goldblatt, J; Landau, LI; Le Souëf, PN; Palmer, LJ; Rye, PJ; Turner, SW; Young, S, 2005) |
"It is still uncertain how viral respiratory infections cause acute exacerbations of bronchial asthma, although several mechanisms have been proposed." | 1.33 | Inflammatory and bronchospastic factors in asthma exacerbations caused by upper respiratory tract infections. ( Ishizuka, S; Kubo, H; Nishimura, H; Sasaki, T; Sekizawa, K; Suzuki, T; Yamaya, M; Yasuda, H; Zayasu, K, 2005) |
"Histamine PC20 was correlated with IL-5 in CVA, whereas it was associated with sputum eosinophilia in CA." | 1.33 | Airway inflammation and cough sensitivity in cough-variant asthma. ( Compte, L; De Diego, A; Macián, V; Martínez, E; Nieto, L; Perpiñá, M; Senent, L, 2005) |
"Distal airway obstruction was estimated by measuring the ventilated alveolar area after inhaled xenon administration." | 1.33 | Differences in the time course of proximal and distal airway response to inhaled histamine studied by synchrotron radiation CT. ( Bayat, S; Nemoz, C; Porra, L; Sovijärvi, AR; Suhonen, H; Suortti, P, 2006) |
"Although bronchial asthma is well known as an inflammatory disease that shows obvious circadian rhythms of airway narrowing, it remains to be elucidated whether the suprachiasmatic nucleus (SCN), a major circadian pacemaker, regulates inflammatory mediators relevant to asthma." | 1.33 | Lesions in the suprachiasmatic nuclei suppress inflammatory mediators in sensitized rats. ( Endo, Y; Irie, M, 2006) |
"Histamine is an important mediator in airway inflammation." | 1.33 | The role of antihistamines in asthma management. ( Wilson, AM, 2006) |
"Histamine production was about 1 mcg/mL at streptococci, staphylococci and hemophilic bacteria, from 1 to 3 mcg/mL - at bacilli, corynebacteria and Candida, from 1 to 10 mcg/mL - at lactobacilli, enterobacteria, pseudomonades, acinetobacteria." | 1.31 | [Resistance to antibiotics and histamine production at the bacteria, isolated from the stomatopharynx of the children with bronchial asthma]. ( Voropaeva, EA, 2002) |
"90 of them had chronic bronchitis, 35--bronchial asthma." | 1.31 | [Biochemical markers of inflammation and bronchial obstruction]. ( Gel'tser, BI; Kulakova, NV; Luk'ianov, PA; Nevzorova, VA, 2000) |
"Histamine challenge was performed by the dosimeter method and provocative dose causing a 20% fall in forced expiratory volume in one second (PD20) (FEV1) was calculated." | 1.31 | Magnesium levels in plasma and erythrocytes before and after histamine challenge. ( Kalogeropoulos, N; Loukides, S; Panagou, P; Papatheodorou, G; Psathakis, K; Tsindiris, K; Zervas, E, 2000) |
"The ability to prevent or treat viral respiratory tract infections is currently limited." | 1.31 | Virus-induced asthma attacks. ( Jacoby, DB, 2002) |
"Pretreatment with pyrilamine, an antihistamine, suppressed the increase in RL in immature animals, whereas the remaining component of the increase in RL was seen in adult animals." | 1.30 | Effect of maturation on allergen-induced airflow obstruction and airway plasma exudation in sensitized guinea pigs. ( Arakawa, H; Lötvall, J; Mochizuki, H; Morikawa, A; Tokuyama, K, 1997) |
"001); and similarly a decline in histamine dose-response slope was observed." | 1.30 | Longitudinal determinants of bronchial responsiveness to inhaled histamine. ( Backer, V; Ulrik, CS, 1998) |
" The quantitative traits assessed included serum levels of total IgE and specific IgE to house dust mite and mixed grass, blood eosinophil counts, and the dose-response slope (DRS) of FEV1 to histamine provocation." | 1.30 | Linkage of chromosome 5q and 11q gene markers to asthma-associated quantitative traits in Australian children. ( Burton, PR; Cookson, WO; Daniels, SE; Gibson, NA; Goldblatt, J; LeSöuef, PN; Palmer, LJ; Rye, PJ; Tay, GK, 1998) |
" Exhaled NO correlated significantly with airway responsiveness, measured as the dose-response ratio to histamine (r = 0." | 1.30 | Exhaled nitric oxide measurements in a population sample of young adults. ( Brown, NJ; Dermand, J; Marks, GB; Roberts, AM; Salome, CM; Woolcock, AJ, 1999) |
"The results showed that cough during airway obstruction did not relate to other variables." | 1.30 | Cough as the ambiguous indicator of airway obstruction in asthma. ( Prins, PJ; Rietveld, S; Rijssenbeek-Nouwens, LH, 1999) |
"Skin blisters were induced on the forearms and challenged with allergen or phosphate-buffered saline (PBS)." | 1.30 | Allergen-induced accumulation of eosinophils and lymphocytes in skin chambers is associated with increased levels of interleukin-4 and sVCAM-1. ( Alkner, U; Fernvik, E; Grönneberg, R; Halldén, G; Lundahl, J; Raud, J; van Hage-Hamsten, M, 1999) |
"We have recently found that changes in lung sounds correspond well with a 20% fall in the forced expiratory volume in 1 s (FEV1) after methacholine challenge in asthmatic children." | 1.30 | Agreement between spirometry and tracheal auscultation in assessing bronchial responsiveness in asthmatic children. ( Heymans, HS; Lourens, MS; Schouten, JP; Sprikkelman, AB; van Aalderen, WM, 1999) |
" Baseline respiratory values and dose-response slope of the subsample were also not significantly different." | 1.29 | Chronic respiratory symptoms, bronchial responsiveness and dietary sodium and potassium: a population-based study. ( Basso, O; Bruschi, C; Casali, L; Cerveri, I; De Marco, R; Fanfulla, F; Zoia, MC, 1995) |
"The inhibition of this pulmonary eosinophilia and bronchial hyperresponsiveness by TRFK-5 was seen for up to 3 mo after treatment." | 1.29 | Effects of an antibody to interleukin-5 in a monkey model of asthma. ( Adams, GK; Chapman, RW; Egan, RW; Fernandez, X; Foran, SK; Kreutner, W; Mauser, PJ; Pitman, AM, 1995) |
" The correlation (r) between % fall in FEV1 to exercise challenge and dose-response ratio to histamine challenge was 0." | 1.29 | An exercise challenge for epidemiological studies of childhood asthma: validity and repeatability. ( Anderson, SD; Haby, MM; Mellis, CM; Peat, JK; Woolcock, AJ, 1995) |
"The histamine effects were specific, since they were significantly inhibited by an H1-blocker, pyrilamine, used at a concentration of 10 microM." | 1.29 | Phenotypic and functional modulation of normal human alveolar macrophages by histamine. ( Bousquet, J; Chanez, P; Godard, P; Paul-Eugène, N; Paul-Lacoste, P; Vignola, AM, 1994) |
" To explain the differing discriminant ability of the six provocation doses (PD20 = PD15 > PD10T = PD40 > PD20C > PD10), this study analyzed the role of % delta/variability, log dose-response curve, airway hysteresis and the test itself in the original group of 20 normal and 20 asthmatic subjects." | 1.29 | Physiologic factors affecting the discriminant ability of provocation doses to histamine. ( Popa, V, 1994) |
"The diagnosis of bronchial asthma was confirmed in all patients; however, 4 patients were excluded from the study as they had a baseline PC20 FEV1 histamine > 8 mg/ml." | 1.29 | Usefulness of repeated measurements of bronchial hyperresponsiveness for the diagnosis of occupational asthma. ( Backer, V; Skov, PG; Ulrik, CS, 1994) |
" The degree of bronchial responsiveness as indicated by the dose-response slope (DRS), the percentage change in forced expiratory volume in 1 sec (FEV1) per inhaled mumol of histamine, was found to be significantly higher in previously asthmatic patients (median logDRS 0." | 1.29 | Bronchial responsiveness in children and adolescents: a comparison between previously asthmatic, currently asthmatic, and normal subjects. ( Bach-Mortensen, N; Backer, V; Hansen, KK; Koch, C; Laursen, EM; Prahl, P, 1994) |
"A histamine challenge was performed before and 24 h after the HDM challenge." | 1.29 | Effect of a bronchial provocation test with house-dust mite on blood eosinophilia, eosinophil cationic protein, soluble interleukin-2 receptor, and interleukin-6 in asthmatic children. ( Bosmans, E; Bridts, CH; De Clerck, LS; Mertens, AV; Moens, MM; Stevens, WJ; Van Bever, HP, 1993) |
"Histamine plays a major part in food and wine intolerance." | 1.29 | [The histamine-free diet]. ( Götz, M; Jarisch, R; Wantke, F, 1993) |
"Histamine challenges were performed before and an average of 5 months after the consecutive treatment." | 1.29 | Bronchial hyperresponsiveness changes after 5 months of regular procaterol inhalation therapy in asthmatic children. ( Aoki, T; Iikura, Y; Kishida, M; Saito, S; Sasamoto, A, 1993) |
" Addition of antihistamines (mepyramine and metiamide) to the organ bath abolished the response to exogenous histamine, but failed to alter the dose-response relationship of the reaction to cumulative challenge with rising titres of anti-IgE." | 1.29 | Leukotrienes and histamine mediate IgE-dependent contractions of human bronchi: pharmacological evidence obtained with tissues from asthmatic and non-asthmatic subjects. ( Björck, T; Dahlén, SE, 1993) |
" We report the results of analyzing bronchial dose-response curves by measuring percent fall in vital capacity (delta FVC%) as the response rather than the PC20." | 1.29 | Detection of excessive bronchoconstriction in asthma. ( Gibbons, WJ; Lougheed, D; Macklem, PT; Sharma, A, 1996) |
"Pretreatment with rolipram (10 mg kg-1, i." | 1.29 | Effects of selective phosphodiesterase inhibitors on platelet-activating factor- and antigen-induced airway hyperreactivity, eosinophil accumulation, and microvascular leakage in guinea pigs. ( Cortijo, J; Martí-Cabrera, M; Morcillo, EJ; Ortiz, JL; Vallés, JM, 1996) |
"Treatment with rolipram, but not theophylline, prevented the increase in responsiveness to inhaled histamine 24 h after antigen challenge." | 1.29 | Effects of theophylline and rolipram on antigen-induced airway responses in neonatally immunized rabbits. ( Blake, SM; Gozzard, N; Herd, CM; Higgs, GA; Holbrook, M; Hughes, B; Page, CP, 1996) |
" The same general protocol was used for all studies, except that the dosage and time of TYB-2285 treatment was varied." | 1.29 | Effect of TYB-2285 on antigen-induced airway responses in sheep. ( Abraham, WM; Ahmed, A; Cortes, A; Sielczak, M; Wantanabe, A, 1996) |
" Given orally, RP 58802B (5 mg/kg, 60 min before challenge) produced a greater than three-fold shift to the right of the dose-response curve and depressed the maximum response to histamine by 39 +/- 11%." | 1.28 | RP 58802B, a long-acting beta 2-adrenoceptor agonist: assessment of antiasthma activity in the guinea-pig in vivo. ( Lewis, SA; Raeburn, D; Underwood, SL, 1992) |
"For describing bronchial responsiveness, it has been suggested that the dose-response slope (DRS), which is the linear slope of the dose-response curve, is a more useful measure of severity than the provoking dose that causes a 20% fall in FEV1 (PD20FEV1)." | 1.28 | Relation of dose-response slope to respiratory symptoms and lung function in a population study of adults living in Busselton, Western Australia. ( Berry, G; Peat, JK; Salome, CM; Woolcock, AJ, 1992) |
"We investigated the effects of inhaled beclomethasone dipropionate (BDP) on airway sensitivity (provocative dose producing a 20% fall in forced expiratory volume in one second (FEV1) from baseline (PD20)) and reactivity (slope of the dose-response curve) to inhaled aerosols of hyperosmolar (4." | 1.28 | Inhaled steroids modify bronchial responses to hyperosmolar saline. ( Anderson, SD; Rodwell, LT; Seale, JP, 1992) |
"The effect of medication on peripheral airway obstruction was examined in cases of bronchial asthma." | 1.28 | [Peripheral airway obstruction and treatment]. ( Horie, T; Koyama, S; Majima, T; Mutoh, T; Ohmori, C; Ohtsuka, A; Yamaguchi, M, 1992) |
"This study was designed to investigate if two equivalent doses of allergen administered by different dosing regimes--two breaths and 10 breaths of each concentration--would result in the same magnitude of the early and late asthmatic response." | 1.28 | Bronchial allergen challenge: dose versus concentration. ( Frølund, L; Heinig, JH; Madsen, F; Scharling, B; Svendsen, UG, 1992) |
" While pretreatment with inhaled AS-35 (1mg) did not affect the STA2 dose-response curve." | 1.28 | Interaction of thromboxane A2 and leukotrienes in guinea pig airways in vivo. ( Bando, T; Fujimura, M; Matsuda, T; Mizuhashi, K, 1991) |
" The measurements derived from the dose-response curve were the PD20 FEV1, which was measured as the provoking dose causing a 20% fall in FEV1, and the dose-response slope (DRS), which was measured as the percentage fall in FEV1 at final dose/total dose administered." | 1.28 | Repeatability of histamine bronchial challenge and comparability with methacholine bronchial challenge in a population of Australian schoolchildren. ( Bauman, A; Peat, JK; Salome, CM; Toelle, BG; Wachinger, SL; Woolcock, AJ, 1991) |
"To describe bronchial responsiveness in populations, the dose-response slope (DRS), which is the linear slope of the dose-response curve, may be a more useful measure of severity than the provoking dose that causes a 20% fall in FEV1 (PD20 FEV1)." | 1.28 | Relation of dose-response slope to respiratory symptoms in a population of Australian schoolchildren. ( Berry, G; Peat, JK; Salome, CM; Woolcock, AJ, 1991) |
" Dose-response lines in response to the two agonists, expressed as percent maximal contraction, did not differ among the groups." | 1.28 | Muscarinic-receptor functioning in tracheas from normal and ovalbumin-sensitive guinea pigs. ( Biggs, DF; Yang, ZJ, 1991) |
"Erythromycin is an antibiotic extensively used worldwide which is also reported to have anti-inflammatory action." | 1.28 | Erythromycin reduces the severity of bronchial hyperresponsiveness in asthma. ( Miyatake, H; Satake, T; Suzuki, R; Takagi, K; Taki, F; Taniguchi, H, 1991) |
" However, a dose-response curve to methacholine is helpful." | 1.28 | Characteristics of bronchial hyperresponsiveness in chronic obstructive pulmonary disease and in asthma. ( Anderson, SD; Du Toit, JI; Peat, JK; Salome, CM; Smith, CM; Woolcock, AJ; Zhang, YG, 1991) |
"Histamine challenge was performed in 19 patients using two nebulizers (PARI and Wright) and FEV1 and PEF were measured to determine PC20 histamine." | 1.28 | Measurement of PC20 histamine with the use of two different nebulizers and measurement of FEV1 and PEF. ( Harving, H; Iversen, M; Pedersen, B, 1991) |
"Histamine levels were increased fourfold in asthmatic subjects compared with those in normal subjects (p less than 0." | 1.28 | Evidence for elevated levels of histamine, prostaglandin D2, and other bronchoconstricting prostaglandins in the airways of subjects with mild asthma. ( Bleecker, ER; Hubbard, WC; Kagey-Sobotka, A; Lichtenstein, LM; Liu, MC; McLemore, TL; Niv, Y; Permutt, S; Proud, D, 1990) |
"The relationship of gastro oesophageal reflux (GER) with bronchial asthma has already been well documented in asthmatic subjects and it has been postulated that their asthma might have been caused by GER disease." | 1.28 | Histamine bronchoprovocation tests in subjects with gastro-oesophageal reflux disease. ( Agarwal, A; Bhandari, VM; Gupta, AN; Rishi, JP, 1990) |
"We treated bronchial asthma patients with anti-allergic agents for more than three months, and examined their effects on the airway hyperreactivity in 15 cases; five were short cases (disease duration was less than one year from the onset) and 10 were long cases (disease duration was more than one year)." | 1.28 | [Improvement of airway hyperreactivity in bronchial asthma patients with short disease duration treated with anti-allergic agents]. ( Hoshino, K; Kawasaki, A; Mizushima, Y; Yano, S, 1989) |
"Although viral upper respiratory infections (URIs) provoke wheezing in many asthma patients, the effect of these illnesses on the airway response to inhaled antigen is not established." | 1.28 | Rhinovirus upper respiratory infection increases airway hyperreactivity and late asthmatic reactions. ( Busse, WW; Dick, EC; Lemanske, RF; Swenson, CA; Vrtis, RF, 1989) |
" The threshold of sensitivity expressed as PD 20 VEMS and PD 40 sGAW are superimposable by the dosimetric technique but on the other hand, using the aerosol dosage method, the threshold of sensitivity expressed in PD 40 sGAW is significantly lower than that for PD 20 VEMS (p less than 0." | 1.28 | [Comparison of the effect of 2 methods of histamine administration on the bronchomotor response in asthmatics]. ( Duchateau, J; Michel, O; Sergysels, R, 1989) |
" The dose-response curves of terbutaline on isolated tracheae of actively sensitized guinea pigs were significantly shifted to the right in comparison with control trachea (ED50 11." | 1.27 | Mechanical and biochemical alterations in guinea-pig tracheae caused by sensitisation. ( Beier, W; Feddersen, C; Kaukel, E; Koppermann, G; Schrum, C, 1984) |
" The S-shaped dose-response relationship with D2O was shifted to the left in the patients with BR to exercise compared to patients without (P less than 0." | 1.27 | Dysregulation of mediator release in relation to bronchial asthma and bronchial hyperresponsiveness. ( de Jongste, JJ; Degenhart, HJ; Kerrebijn, KF; Neijens, HJ, 1984) |
"Histamine challenges were performed in duplicate after premedication with 0." | 1.27 | Effect of prior bronchoconstriction on the airway response to histamine in normal subjects. ( Chung, KF; Snashall, PD, 1984) |
" In dose-response studies in normal subjects, prostaglandin D2 caused a significant (20 +/- 6 per cent) fall in specific airway conductance after the two highest concentrations (250 and 500 micrograms per milliliter), whereas prostaglandin F2 alpha had no effect." | 1.27 | The bronchoconstrictor effect of inhaled prostaglandin D2 in normal and asthmatic men. ( Hardy, CC; Holgate, ST; Robinson, C; Tattersfield, AE, 1984) |
"To examine for a relationship between in vivo nonspecific bronchial reactivity to histamine and in vitro smooth muscle response to histamine, we performed inhalation dose-response curves prior to lung surgery in 12 patients and compared this with their bronchial smooth muscle response in vitro." | 1.27 | A comparison of in vivo and in vitro human airway reactivity to histamine. ( Armour, CL; Chan, N; Hogg, JC; Lazar, NM; Paré, PD; Schellenberg, RR; Taylor, SM, 1984) |
"Allergic rhinitis was present in 10." | 1.27 | Unimodal distribution of bronchial responsiveness to inhaled histamine in a random human population. ( Berscheid, BA; Cockcroft, DW; Murdock, KY, 1983) |
"The value of determining the slope of the histamine dose-response curve, in addition to the histamine provocation concentration producing a 20% reduction in FEV1 (PC20-FEV1), was assessed by analysis of histamine dose-response curves in 40 patients selected as having a wide range of increased non-specific bronchial responsiveness to inhaled histamine." | 1.27 | Slope of the dose-response curve: usefulness in assessing bronchial responses to inhaled histamine. ( Berscheid, BA; Cockcroft, DW, 1983) |
"In patients suffering from bronchial asthma and chronic urticaria, the value of histaminopexy was determined prior and after histaglobin treatment (3 injections-1 amp." | 1.27 | Changes of histaminopexy in patients with bronchial asthma and chronic urticaria after histaglobin administration. ( Liebhart, E; Liebhart, J; Małolepszy, J; Nadobna, G; Zak-Najmark, T, 1986) |
" It was found that the same individuals responded with histamine release to the same allergens in both histamine release assays, and the dose-response curves were almost identical." | 1.27 | A new glass microfibre-based histamine analysis for allergy testing in children. Results compared with conventional leukocyte histamine release assay, skin prick test, bronchial provocation test and RAST. ( Nolte, H; Schiøtz, O; Skov, PS, 1987) |
" There was a highly significant correlation between the number of cigarettes the mother smoked in the house and each of these lung function test results, indicating a dose-response relationship." | 1.27 | Passive smoking and the seasonal difference of severity of asthma in children. ( Morrison, BJ; Murray, AB, 1988) |
"Histamine levels were significantly higher in children with post-therapy improvement in PEFR of less than 20% (2,560 +/- 1,600) compared with those with greater than 20% (475 +/- 100), and in hospitalized (3,915 +/- 1,910) compared with nonhospitalized (408 +/- 130) children." | 1.27 | Plasma elevations of histamine and a prostaglandin metabolite in acute asthma. ( Asman, B; Fireman, P; Gillen, L; Page, R; Skoner, DP, 1988) |
"Histamine is a widely distributed amine with many functions, both physiological and pathological." | 1.27 | Relevance of histamine to the anaesthetist. ( Withington, DE, 1988) |
"A histamine challenge was performed." | 1.27 | Influence of asthmatic and rhinitic symptomatology duration on bronchial responsiveness to histamine. ( Crimi, N; Distefano, SM; Mistretta, A; Oliveri, R; Palermo, B; Palermo, F; Polosa, R; Vancheri, C, 1987) |
" Several methods for summarising the information in the dose-response curve obtained from a histamine challenge test have been compared." | 1.27 | Estimation and repeatability of the response to inhaled histamine in a community survey. ( Britton, JR; Burney, PG; Chinn, S; Papacosta, AO; Tattersfield, AE, 1987) |
" Simultaneous dosing with PGD2 caused a significant increase in reactivity to histamine, mean dose of histamine causing a 35% fall in specific airway conductance being 0." | 1.27 | Prostaglandin D2 potentiates airway responsiveness to histamine and methacholine. ( Barnes, PJ; Dixon, CM; Dollery, CT; Fuller, RW, 1986) |
"Isoproterenol responses were determined against a half-maximal methacholine contraction." | 1.27 | Comparison of drug responses in vivo and in vitro in airways of dogs with and without airway hyperresponsiveness. ( Austin, DR; Downes, H; Hirshman, CA; Parks, CM, 1986) |
" We investigated whether this limitation is due to a nonspecific inhibitory mechanism (with regard to the agonist) by comparing the maximal response plateaus of histamine and methacholine dose-response curves." | 1.27 | Maximal airway narrowing in humans in vivo. Histamine compared with methacholine. ( Dijkman, JH; Sterk, PJ; Timmers, MC, 1986) |
" Second, the histamine or methacholine dose-response curve differs in asthmatics with a moderate to severe increase in airway responsiveness from asthmatics with a mild increase in responsiveness or nonasthmatics." | 1.27 | Airway responsiveness to histamine or methacholine: advances in measurement and interpretation. ( Adelroth, EC; Hargreave, FE; O'Byrne, PM; Ramsdale, EH; Sterk, P, 1986) |
"To determine if clinical concentrations of halothane have direct relaxant effects on airway smooth muscle, the authors compared dose-response curves to histamine in the control state (thiopental) and during halothane anesthesia (1." | 1.27 | Mode of action of halothane on histamine-induced airway constriction in dogs with reactive airways. ( Hirshman, CA; Shah, MV, 1986) |
" The slopes of log dose-response curves (SLDRC) to H and SLDRC to ACH were of similar magnitude both in N and AST and linearly related; however, for either agonist, bronchial sensitivity (PD40) and reactivity (SLDRC) failed to correlate." | 1.27 | The relationship between acetylcholine- and histamine-induced constriction of large airways in normal subjects and subjects with asthma: a possible role for postreceptor mechanisms. ( Popa, V, 1986) |
" The IAR showed a very good reproducibility and significant dose-response relationship (P less than ." | 1.27 | The immediate asthmatic response to allergen challenge. ( Berger, MP; Kruis, M; Pelikan, M; Pelikan, Z, 1986) |
" In 6 subjects in whom dose-response curves were obtained, the mean deposited histamine mass required to decrease the FEV1 by 10% was 0." | 1.27 | Variability of airway responsiveness to histamine aerosol in normal subjects. Role of deposition. ( Brodnan, JM; Henke, KG; Kim, CS; Perez, J; Wanner, A, 1985) |
"Higher counts were noted in cryptogenic fibrosing alveolitis--0." | 1.27 | Mast cell and histamine content of human bronchoalveolar lavage fluid. ( Agius, RM; Godfrey, RC; Holgate, ST, 1985) |
" In each airway segment, cumulative dose-response effects of ovalbumin were obtained in the absence and presence of a maximally effective concentration of a beta adrenergic receptor agonist, sulfonterol." | 1.26 | Parainfluenza 3 infection blocks the ability of a beta adrenergic receptor agonist to inhibit antigen-induced contraction of guinea pig isolated airway smooth muscle. ( Ain-Shoka, AA; Buckner, CK; Busse, WW; Clayton, DE; Dick, EC; Shult, P, 1981) |
"Histamine release was significantly increased in 4 day-vaccinated animals but not 1 or 10 days after vaccination, while broncho-constriction was potentiated in 1 and in 4 day-vaccinated animals." | 1.26 | The effects of Haemophilus influenzae vaccination on anaphylactic mediator release and isoprenaline-induced inhibition of mediator release. ( Nijkamp, FP; Raaijmakers, JA; Schreurs, AJ; Terpstra, GK, 1980) |
" The S-shaped dose-response relationship with D2O was shifted to the left in the patients with BR to exercise compared to patients without (P less than 0 X 025)." | 1.26 | Release of histamine from leucocytes and its determinants in vitro in relation to bronchial responsiveness to inhaled histamine and exercise in vivo. ( Degenhart, HJ; Kerrebijn, KF; Neijens, HJ; Raatgeep, HC, 1982) |
"Upper respiratory tract infection has frequently been shown to precipitate or exacerbate the asthmatic condition and to increase airway reactivity to bronchospastic agents." | 1.26 | Pharmacological abnormality in bronchial asthma and the role of respiratory pathogens. ( Eyre, P; Norris, AA, 1982) |
"Live attenuated influenza A virus (R." | 1.26 | Bronchial reactivity following uncomplicated influenza A infection in healthy subjects and in asthmatic patients. ( Kava, T; Laitinen, LA, 1980) |
" It is necessary to collect sufficient background factors and to use proper dose-response studies." | 1.26 | Clinical implications of bronchial hyperreactivity. ( Simonsson, BG, 1980) |
" The development of resistance was assessed from salbutamol dose-response studies in which the airway response was measured as specific airway conductance (sGaw)." | 1.26 | Airway response to salbutamol: effect of regular salbutamol inhalations in normal, atopic, and asthmatic subjects. ( Harvey, JE; Tattersfield, AE, 1982) |
"Histamine challenges were performed on a heterogeneous group of adult asthmatic subjects." | 1.26 | Further studies on the mechanism of human histamine-induced asthma: the effect of an aerosolized H1 receptor antagonist (diphenhydramine). ( Casterline, CL; Evans, R, 1977) |
"Some aspects of bronchomotricity in bronchial asthma, with special emphasis on pharmacological and immunological data, are presented." | 1.26 | [Bronchial reactivity in asthma. Immunopharmacological data]. ( Palma-Carlos, AG; Palma-Carlos, ML; Trindade, JG, 1977) |
"Histamine and IgE were present in considerable amounts in the sputum of bronchitics and early-onset, skin-test-positive asthmatics." | 1.26 | Mediators of immediate-type hypersensitivity in sputum from patients with chronic bronchitis and asthma. ( Crofton, JW; Kay, AB; Leitch, AG; Turnbull, LS; Turnbull, LW, 1977) |
"We performed dose-response curves to inhaled histamine (H) and methacholine (MC) in a group of eight rhesus monkeys, with and without natural allergy to Ascaris suum antigen (AA)." | 1.26 | Airway responses to histamine and methocholine in Ascaris suum-allergic rhesus monkeys. ( Boucher, R; Hogg, JC; Michoud, MC; Paré, PD, 1978) |
" The aerosol/infusion dosage ratio for comparable reductions of blood pressure were 1 for isoprenaline, and 10 for NP." | 1.26 | Comparison of sodium nitroprusside and isoprenaline aerosols in histamine-induced bronchial asthma of the guinea pig. ( Kreye, VA; Marquard, E, 1979) |
"Bronchial hyperreactivity, typical of bronchial asthma, was observed in 48." | 1.26 | Perennial atopic rhinitis as an early stage of bronchial asthma. ( Gniazdowski, R, 1979) |
" Dose-response curves and time course to MCh challenge differed in CF and asthma." | 1.26 | Bronchial hyperreactivity in cystic fibrosis and asthma. ( Corey, M; Krastins, IR; Levison, H; Mitchell, I; Woenne, R, 1978) |
"An easy and safe dose-response histamine-inhalation test is described, to measure the level of non-specific bronchial reactivity." | 1.26 | Bronchial reactivity to inhaled histamine: a method and clinical survey. ( Cockcroft, DW; Hargreave, FE; Killian, DN; Mellon, JJ, 1977) |
" In three dogs the effect of vagal stimulation was to produce a shift in the dose-response curve to inhaled histamine." | 1.26 | Bronchial reactivity: interaction between vagal stimulation and inhaled histamine. ( Benson, MK; Graf, PD, 1977) |
"Seven patients with bronchial asthma underwent bronchial inhalation challenge with aerosolized allergen extracts and methacholine." | 1.26 | Plasma histamine changes during provoked bronchospasm in asthmatic patients. ( Arroyave, CM; Bhat, KN; Marney, SR; Stevenson, DD; Tan, EM, 1976) |
"Histamine was released from the lung and was not attributable to the concomitant hypoxia." | 1.25 | Histamine release during antigen inhalation in experimental asthma in dogs. ( Chiesa, A; Dain, D; Gold, WM; Kessler, GF; Meyers, GL, 1975) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1232 (56.80) | 18.7374 |
1990's | 599 (27.62) | 18.2507 |
2000's | 196 (9.04) | 29.6817 |
2010's | 120 (5.53) | 24.3611 |
2020's | 22 (1.01) | 2.80 |
Authors | Studies |
---|---|
Tichenor, MS | 1 |
Thurmond, RL | 1 |
Venable, JD | 1 |
Savall, BM | 1 |
Bai, H | 1 |
Xue, Z | 2 |
Zhang, W | 2 |
Feng, C | 1 |
Zhou, Z | 3 |
Hu, S | 1 |
Zhang, Y | 8 |
Qin, Q | 1 |
Wu, Y | 3 |
Sun, X | 2 |
Zhou, Y | 5 |
Wang, N | 1 |
Arora, P | 1 |
Nainwal, LM | 1 |
Gupta, G | 1 |
Singh, SK | 1 |
Chellappan, DK | 1 |
Oliver, BG | 3 |
Dua, K | 1 |
Fang, XM | 1 |
Liu, Y | 9 |
Wang, J | 8 |
Zhang, X | 7 |
Wang, L | 4 |
Zhang, L | 4 |
Zhang, HP | 1 |
Liu, L | 1 |
Huang, D | 2 |
Liu, D | 1 |
Deng, K | 1 |
Luo, FM | 1 |
Wan, HJ | 1 |
Li, WM | 1 |
Wang, G | 1 |
Imraish, A | 1 |
Abu-Thiab, T | 1 |
Alhindi, T | 1 |
Zihlif, M | 1 |
Huang, WY | 1 |
Lee, SH | 1 |
Oh, SJ | 1 |
Yoon, H | 1 |
Pan, JH | 1 |
Jeong, I | 1 |
Kim, MJ | 2 |
Han, BK | 1 |
Kim, JK | 1 |
Shin, EC | 1 |
Kim, YJ | 1 |
Kawakami, Y | 2 |
Takazawa, I | 1 |
Fajt, ML | 1 |
Kasakura, K | 1 |
Lin, J | 1 |
Ferrer, J | 1 |
Kantor, DB | 1 |
Phipatanakul, W | 1 |
Heymann, PW | 1 |
Benedict, CA | 1 |
Kawakami, T | 1 |
van Odijk, J | 1 |
Weisheit, A | 1 |
Arvidsson, M | 1 |
Miron, N | 1 |
Nwaru, B | 1 |
Ekerljung, L | 1 |
de Vreede, CC | 1 |
Witte, JA | 1 |
Kappen, JH | 1 |
Braunstahl, GJ | 1 |
Hempel, P | 1 |
Klein, V | 1 |
Michely, A | 1 |
Böll, S | 1 |
Rieg, AD | 1 |
Spillner, J | 1 |
Braunschweig, T | 1 |
von Stillfried, S | 1 |
Wagner, N | 1 |
Martin, C | 1 |
Tenbrock, K | 1 |
Verjans, E | 1 |
Parikh, V | 1 |
Scala, J | 1 |
Patel, R | 1 |
Corbi, C | 1 |
Lo, D | 1 |
Bochkov, YA | 1 |
Kennedy, JL | 1 |
Kurten, RC | 2 |
Liggett, SB | 2 |
Gern, JE | 1 |
Koziol-White, CJ | 1 |
Sirufo, MM | 1 |
Suppa, M | 1 |
Ginaldi, L | 1 |
De Martinis, M | 1 |
Zhang, GS | 1 |
Qiu, RR | 1 |
Pan, J | 2 |
Zhang, J | 4 |
Zhang, C | 4 |
Wang, CX | 1 |
Yang, RD | 1 |
Halim, AA | 1 |
Alsayed, B | 1 |
Embarak, S | 1 |
Yaseen, T | 1 |
Dabbous, S | 1 |
Fontaine, O | 1 |
Dueluzeau, R | 1 |
Raibaud, P | 1 |
Chabanet, C | 1 |
Popoff, MR | 1 |
Badoual, J | 1 |
Gabilan, JC | 1 |
Andremont, A | 1 |
Gómez, L | 1 |
Andrés, S | 1 |
Sánchez, J | 1 |
Alonso, JM | 1 |
Rey, J | 2 |
López, F | 1 |
Jiménez, A | 1 |
Yan, Z | 1 |
Zhou, L | 1 |
Zhao, Y | 3 |
Huang, L | 3 |
Hu, K | 1 |
Liu, H | 4 |
Wang, H | 5 |
Guo, Z | 1 |
Song, Y | 1 |
Huang, H | 4 |
Yang, R | 1 |
Owen, TW | 1 |
Al-Kaysi, RO | 1 |
Bardeen, CJ | 1 |
Cheng, Q | 1 |
Wu, S | 1 |
Cheng, T | 1 |
Zhou, X | 1 |
Wang, B | 4 |
Zhang, Q | 5 |
Wu, X | 2 |
Yao, Y | 3 |
Ochiai, T | 1 |
Ishiguro, H | 2 |
Nakano, R | 2 |
Kubota, Y | 2 |
Hara, M | 2 |
Sunada, K | 1 |
Hashimoto, K | 1 |
Kajioka, J | 1 |
Fujishima, A | 1 |
Jiao, J | 3 |
Gai, QY | 3 |
Wang, W | 3 |
Zang, YP | 2 |
Niu, LL | 2 |
Fu, YJ | 3 |
Wang, X | 4 |
Yao, LP | 1 |
Qin, QP | 1 |
Wang, ZY | 1 |
Liu, J | 6 |
Aleksic Sabo, V | 1 |
Knezevic, P | 1 |
Borges-Argáez, R | 1 |
Chan-Balan, R | 1 |
Cetina-Montejo, L | 1 |
Ayora-Talavera, G | 1 |
Sansores-Peraza, P | 1 |
Gómez-Carballo, J | 1 |
Cáceres-Farfán, M | 1 |
Jang, J | 1 |
Akin, D | 1 |
Bashir, R | 1 |
Yu, Z | 1 |
Zhu, J | 2 |
Jiang, H | 2 |
He, C | 2 |
Xiao, Z | 1 |
Xu, J | 2 |
Sun, Q | 1 |
Han, D | 1 |
Lei, H | 1 |
Zhao, K | 2 |
Zhu, L | 1 |
Li, X | 4 |
Fu, H | 2 |
Wilson, BK | 1 |
Step, DL | 1 |
Maxwell, CL | 1 |
Gifford, CA | 1 |
Richards, CJ | 1 |
Krehbiel, CR | 1 |
Warner, JM | 1 |
Doerr, AJ | 1 |
Erickson, GE | 1 |
Guretzky, JA | 1 |
Rasby, RJ | 1 |
Watson, AK | 1 |
Klopfenstein, TJ | 1 |
Sun, Y | 4 |
Liu, Z | 5 |
Pham, TD | 1 |
Lee, BK | 1 |
Yang, FC | 1 |
Wu, KH | 1 |
Lin, WP | 1 |
Hu, MK | 1 |
Lin, L | 3 |
Shao, J | 1 |
Sun, M | 1 |
Xu, G | 1 |
Xu, N | 1 |
Wang, R | 1 |
Liu, S | 3 |
He, H | 1 |
Dong, X | 2 |
Yang, M | 2 |
Yang, Q | 1 |
Duan, S | 1 |
Yu, Y | 2 |
Han, J | 2 |
Chen, L | 3 |
Yang, X | 1 |
Li, W | 3 |
Wang, T | 2 |
Campbell, DA | 1 |
Gao, K | 1 |
Zager, RA | 1 |
Johnson, ACM | 1 |
Guillem, A | 1 |
Keyser, J | 1 |
Singh, B | 1 |
Steubl, D | 1 |
Schneider, MP | 1 |
Meiselbach, H | 1 |
Nadal, J | 1 |
Schmid, MC | 1 |
Saritas, T | 1 |
Krane, V | 1 |
Sommerer, C | 1 |
Baid-Agrawal, S | 1 |
Voelkl, J | 1 |
Kotsis, F | 1 |
Köttgen, A | 1 |
Eckardt, KU | 1 |
Scherberich, JE | 1 |
Li, H | 4 |
Yao, L | 2 |
Sun, L | 3 |
Zhu, Z | 1 |
Naren, N | 1 |
Zhang, XX | 2 |
Gentile, GL | 1 |
Rupert, AS | 1 |
Carrasco, LI | 1 |
Garcia, EM | 1 |
Kumar, NG | 1 |
Walsh, SW | 1 |
Jefferson, KK | 1 |
Guest, RL | 1 |
Samé Guerra, D | 1 |
Wissler, M | 1 |
Grimm, J | 1 |
Silhavy, TJ | 1 |
Lee, JH | 3 |
Yoo, JS | 1 |
Kim, Y | 1 |
Kim, JS | 2 |
Lee, EJ | 1 |
Roe, JH | 1 |
Delorme, M | 1 |
Bouchard, PA | 1 |
Simon, M | 1 |
Simard, S | 1 |
Lellouche, F | 1 |
D'Urzo, KA | 1 |
Mok, F | 1 |
D'Urzo, AD | 1 |
Koneru, B | 1 |
Lopez, G | 1 |
Farooqi, A | 1 |
Conkrite, KL | 1 |
Nguyen, TH | 1 |
Macha, SJ | 1 |
Modi, A | 1 |
Rokita, JL | 1 |
Urias, E | 1 |
Hindle, A | 1 |
Davidson, H | 1 |
Mccoy, K | 1 |
Nance, J | 1 |
Yazdani, V | 1 |
Irwin, MS | 1 |
Yang, S | 1 |
Wheeler, DA | 1 |
Maris, JM | 1 |
Diskin, SJ | 1 |
Reynolds, CP | 1 |
Abhilash, L | 1 |
Kalliyil, A | 1 |
Sheeba, V | 1 |
Hartley, AM | 2 |
Meunier, B | 2 |
Pinotsis, N | 1 |
Maréchal, A | 2 |
Xu, JY | 1 |
Genko, N | 1 |
Haraux, F | 1 |
Rich, PR | 1 |
Kamalanathan, M | 1 |
Doyle, SM | 1 |
Xu, C | 1 |
Achberger, AM | 1 |
Wade, TL | 1 |
Schwehr, K | 1 |
Santschi, PH | 1 |
Sylvan, JB | 1 |
Quigg, A | 1 |
Leong, W | 1 |
Xu, W | 2 |
Gao, S | 1 |
Zhai, X | 1 |
Wang, C | 2 |
Gilson, E | 1 |
Ye, J | 1 |
Lu, Y | 1 |
Yan, R | 1 |
Hu, Z | 1 |
You, Q | 1 |
Cai, Q | 1 |
Yang, D | 1 |
Gu, S | 1 |
Dai, H | 3 |
Zhao, X | 1 |
Gui, C | 1 |
Gui, J | 1 |
Wu, PK | 1 |
Hong, SK | 1 |
Starenki, D | 1 |
Oshima, K | 1 |
Shao, H | 1 |
Gestwicki, JE | 1 |
Tsai, S | 1 |
Park, JI | 1 |
Wang, Y | 11 |
Zhao, R | 1 |
Gu, Z | 1 |
Dong, C | 2 |
Guo, G | 1 |
Li, L | 7 |
Barrett, HE | 1 |
Meester, EJ | 1 |
van Gaalen, K | 1 |
van der Heiden, K | 1 |
Krenning, BJ | 1 |
Beekman, FJ | 1 |
de Blois, E | 1 |
de Swart, J | 1 |
Verhagen, HJ | 1 |
Maina, T | 1 |
Nock, BA | 1 |
Norenberg, JP | 1 |
de Jong, M | 1 |
Gijsen, FJH | 1 |
Bernsen, MR | 1 |
Martínez-Milla, J | 1 |
Galán-Arriola, C | 1 |
Carnero, M | 1 |
Cobiella, J | 1 |
Pérez-Camargo, D | 1 |
Bautista-Hernández, V | 1 |
Rigol, M | 1 |
Solanes, N | 1 |
Villena-Gutierrez, R | 1 |
Lobo, M | 1 |
Mateo, J | 1 |
Vilchez-Tschischke, JP | 1 |
Salinas, B | 1 |
Cussó, L | 1 |
López, GJ | 1 |
Fuster, V | 1 |
Desco, M | 1 |
Sanchez-González, J | 1 |
Ibanez, B | 1 |
van den Berg, P | 1 |
Schweitzer, DH | 1 |
van Haard, PMM | 1 |
Geusens, PP | 1 |
van den Bergh, JP | 1 |
Zhu, X | 1 |
Huang, X | 2 |
Xu, H | 2 |
Yang, G | 2 |
Lin, Z | 1 |
Salem, HF | 1 |
Nafady, MM | 1 |
Kharshoum, RM | 1 |
Abd El-Ghafar, OA | 1 |
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Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Is Adenosine Monophosphate Superior to Histamine for Bronchial Provocation Test in Evaluation of Asthma?[NCT02318043] | 84 participants (Actual) | Interventional | 2007-01-31 | Completed | |||
Evaluation of Beta Blockers for the Treatment of Asthma. A Randomised Controlled Trial of Propranolol[NCT01074853] | Phase 2 | 18 participants (Actual) | Interventional | 2010-05-31 | Completed | ||
Effect of Salmeterol on Brain-Derived Neurotrophic Factor (BDNF) Concentrations in Asthma[NCT00736801] | 35 participants (Actual) | Interventional | 2005-09-30 | Completed | |||
Kinetics of IgE Memory B Cells, Plasmablasts and Plasma Cells After Whole Lung Allergen Challenge in Mild Asthmatics[NCT01420003] | 12 participants (Actual) | Interventional | 2011-11-30 | Completed | |||
Exercise-induced Bronchoconstriction in a Cold Chamber Compared to Methacholine Challenge[NCT02026492] | 79 participants (Actual) | Interventional | 2013-06-30 | Completed | |||
Effects of Symbicort Single Inhaler Therapy on Bronchial Hyper Responsiveness, Asthma Control and Safety in Mild to Moderate Asthmatics in General Practice, Compared to Usual Care Therapy[NCT00235911] | Phase 3 | 100 participants | Interventional | 2003-09-30 | Completed | ||
Reversal of Acute β-Blocker Induced Bronchoconstriction[NCT01070225] | Phase 4 | 14 participants (Actual) | Interventional | 2010-03-31 | Completed | ||
[NCT00005359] | 0 participants | Observational | 1994-07-31 | Completed | |||
Effect of Oral Procaterol on Chronic Persistent Cough Following Upper Respiratory Tract Infection: Double-Blind Randomized Placebo-Controlled Trial[NCT02349919] | 74 participants (Anticipated) | Interventional | 2015-03-31 | Recruiting | |||
Effect of Continuous Positive Airway Pressure (CPAP) on 6-Minute Walk Test Outcomes in Patients With Excessive Central Airway Collapse (ECAC)[NCT04217603] | 32 participants (Anticipated) | Interventional | 2023-03-01 | Recruiting | |||
More Singing, Less Swinging - Is Singing Related to Improved Postural Control?[NCT05350436] | 160 participants (Anticipated) | Interventional | 2022-02-25 | Recruiting | |||
A Prospective, Single Arm, Cohort Study of Nocturnal Temperature-controlled Laminar Airflow (TLA) Treatment (Airsonett®) in Patients With Allergic Asthma to Determine the Effect of Long-term Treatment on Exacerbation Frequency.[NCT02813811] | 77 participants (Actual) | Observational | 2016-05-24 | Completed | |||
Feasibility of Using a Percutaneous Temporary Placement of a Transvenous Phrenic Nerve Stimulator for Diaphragm Pacing Using Jugular Access[NCT03659552] | 13 participants (Actual) | Interventional | 2018-05-07 | Completed | |||
A Randomized, Double Blind, Placebo-controlled Three-way Crossover Study in Mild Asthmatics to Evaluate the Effect of Smoking Status on the Attenuation by Inhaled Corticosteroids of the Allergen-induced Asthmatic Response.[NCT01400906] | Phase 2 | 36 participants (Actual) | Interventional | 2011-07-20 | Completed | ||
A Randomized Double-Blind Placebo-Controlled Study of the Effect of Traditional Chinese Medicines in the Treatment of Childhood Asthma[NCT00636103] | Phase 1/Phase 2 | 90 participants (Actual) | Interventional | 2002-07-31 | Completed | ||
Comparison of Airway Remodeling Mediators Following Experimental Human Rhinovirus Infection in Subjects With Mild to Moderate Asthma and Healthy, Non-asthmatic Control Subjects[NCT05775952] | 24 participants (Anticipated) | Observational | 2011-09-01 | Recruiting | |||
Late Phase Administration Anakinra as a Rescue Treatment for Inhaled Allergen Challenge-Induced Airway Inflammation[NCT03513458] | Phase 1/Phase 2 | 0 participants (Actual) | Interventional | 2020-09-30 | Withdrawn (stopped due to [The risk of inhaled allergen challenge and anakinra treatment outweigh benefits to participants with allergic asthma due to the COVID-19 pandemic.) | ||
Early Phase Administration of Anakinra as a Rescue Treatment for Inhaled Allergen Challenge-Induced Airway Inflammation[NCT03513471] | Phase 1/Phase 2 | 0 participants (Actual) | Interventional | 2019-08-09 | Withdrawn (stopped due to The risk of inhaled allergen challenge and anakinra treatment outweigh benefits to participants with allergic asthma due to the COVID-19 pandemic.) | ||
Heliox and Posture Optimize Action of Nebulization With Bronchodilators for Asthma Attacks. Randomized Trial.[NCT00922350] | 59 participants (Actual) | Interventional | 2008-06-30 | Completed | |||
Adiposity and Airway Inflammation in HIV-Associated Airway Disease[NCT02975258] | 102 participants (Actual) | Observational | 2015-09-30 | Completed | |||
Exercise Challenge Test in 3-6 Years Old Asthmatic Children[NCT00442715] | 100 participants | Observational | 2006-10-31 | Completed | |||
A Prospective One Year Study of the Causes, Characteristics, Mechanisms and Kinetics of Exacerbations in Subjects With Asthma[NCT00512954] | 100 participants (Anticipated) | Observational | 2007-04-30 | Completed | |||
Evaluation of the Usefulness of Induced Sputum Eosinophilia, eNO and Bronchial Hyperresponsiveness in Predicting the Failure of Inhaled Corticosteroids Dose Reduction in Children and Adolescents With Stable Asthma[NCT03788057] | 50 participants (Anticipated) | Interventional | 2016-02-01 | Recruiting | |||
Effect of Intravenous Administration of C1-inhibitor on Inflammation and Coagulation After Bronchial Instillation of House Dust Mite Allergen and Lipopolysaccharide in Allergic Asthma Patients[NCT03051698] | Phase 4 | 37 participants (Actual) | Interventional | 2016-11-16 | Terminated (stopped due to Interim analysis showed no differences between groups) | ||
Repeatability of a Single Concentration and Single-step Bronchial Allergen Challenge With Grass Pollen[NCT00507039] | 47 participants (Actual) | Observational | 2007-02-28 | Completed | |||
A Pilot Study to Evaluate the Dose-response of Inhaled Formoterol to Inhibit Airway Responsiveness to Methacholine in Patients With Mild Asthma[NCT00643578] | 37 participants (Actual) | Interventional | 2008-03-31 | Completed | |||
Is the Exhaled Nitric Oxide in Infants a Predictive Marker of Asthma?[NCT01239199] | 86 participants (Actual) | Interventional | 2010-01-31 | Completed | |||
[NCT00005279] | 0 participants | Observational | 1971-06-30 | Completed | |||
Does a Lipophilic Steroid Inhaled After an Early Allergic Reaction Affect the Late Reaction?[NCT00716963] | Phase 4 | 7 participants (Actual) | Interventional | 2008-07-31 | Completed | ||
A Retrospective and Prospective, Diagnostic, Open-label, Single-center Study of the Safety of the Bronchial Allergen Challenge With House Dust Mite, Grass Pollen and Alternaria and Predictors for Positive Reaction.[NCT01134757] | 425 participants (Actual) | Interventional | 2011-01-31 | Completed | |||
Role of Epithelial Barrier Integrity in Biologic Treatment Response of Severe Asthmatics With/Out Chronic Rhinosinusitis With Nasal Polyps (CRSwNP). Can Shedding of Epithelial Barrier Proteins be Used as Biomarker in Severe Asthma With/Out CRSwNP Manageme[NCT05365841] | 85 participants (Anticipated) | Observational | 2022-05-15 | Not yet recruiting | |||
Challenge Test for Acetylsalicylic Acid Hypersensitivity[NCT01681615] | 50 participants (Anticipated) | Interventional | 2012-09-30 | Not yet recruiting | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
FEV1 is a measure of lung function and is defined as the maximal amount of air that can be forcefully exhaled in one second. Participants were exposed to an allergen 1 hr after dosing on Day 6. Minimum FEV1 over 4-10 hours post-allergen challenge is the minimum value of all of the post-saline time points between 4 and 10 hrs post-allergen challenge, inclusive of the 4 hr and 10 hr timepoints (i.e., minimum over 4 hrs, 4.5 hrs, 5 hrs, 5.5 hrs, 6 hrs, 6.5 hrs, 7 hrs, 7.5 hrs, 8 hrs, 8.5 hrs, 9 hrs, 9.5 hrs, and 10 hrs). Absolute change from saline at each time point was calculated as the highest allergen challenge FEV1 value minus the highest saline FEV1 value. Data were adjusted for the following covariates: period, smoking status, treatment, participant-level Baseline, period-level Baseline, and treatment by smoking status interaction. (NCT01400906)
Timeframe: Day 6 of each treatment period (up to 11 weeks)
Intervention | Liters (Least Squares Mean) |
---|---|
Placebo | -1.034 |
FP 100 µg | -0.396 |
FP 500 µg | -0.373 |
FEV1 is a measure of lung function and is defined as the maximal amount of air that can be forcefully exhaled in one second. Participants were exposed to an allergen 1 hour after dosing on Day 6. The WM FEV1 was derived by calculating the area under the curve, and then dividing the value by the relevant time interval. LAR WM FEV1 was measured at 4 hrs, 4.5 hrs, 5 hrs, 5.5 hrs, 6 hrs, 6.5 hrs, 7 hrs, 7.5 hrs, 8 hrs, 8.5 hrs, 9 hrs, 9.5 hrs, and 10 hrs post-allergen challenge on Day 6. Absolute change from saline at each time point was calculated as the highest allergen challenge FEV1 value minus the highest saline FEV1 value. Data were adjusted for the following covariates: period, smoking status, treatment, participant-level Baseline, period-level Baseline, and treatment by smoking status interaction. (NCT01400906)
Timeframe: Day 6 of each treatment period (up to 11 weeks)
Intervention | Liters (Least Squares Mean) |
---|---|
Placebo | -0.688 |
FP 100 µg | -0.212 |
FP 500 µg | -0.158 |
FEV1 is a measure of lung function and is defined as the maximal amount of air that can be forcefully exhaled in one second. Participants were exposed to an allergen 1 hour after dosing on Day 6. The WM FEV1 was derived by calculating the area under the curve, and then dividing the value by the relevant time interval. LAR WM FEV1 was measured at 4 hrs, 4.5 hrs, 5 hrs, 5.5 hrs, 6 hrs, 6.5 hrs, 7 hrs, 7.5 hrs, 8 hrs, 8.5 hrs, 9 hrs, 9.5 hrs, and 10 hrs post-allergen challenge on Day 6. Absolute change from saline at each time point was calculated as the highest allergen challenge FEV1 value minus the highest saline FEV1 value. Data were adjusted for the following covariates: period, smoking status, treatment, participant-level Baseline, period-level Baseline, and treatment by smoking status interaction. (NCT01400906)
Timeframe: Day 6 of each treatment period (up to 11 weeks)
Intervention | Liters (Least Squares Mean) |
---|---|
Placebo | -0.364 |
FP 100 µg | -0.188 |
FP 500 µg | -0.198 |
FEV1 is a measure of lung function and is defined as the maximal amount of air that can be forcefully exhaled in one second. Participants were exposed to an allergen 1 hr after dosing on Day 6. Minimum FEV1 over 4-10 hours post-allergen challenge is the minimum value of all of the post-saline time points between 4 and 10 hrs post-allergen challenge, inclusive of the 4 hr and 10 hr timepoints (i.e., minimum over 4 hrs, 4.5 hrs, 5 hrs, 5.5 hrs, 6 hrs, 6.5 hrs, 7 hrs, 7.5 hrs, 8 hrs, 8.5 hrs, 9 hrs, 9.5 hrs, and 10 hrs). Absolute change from saline at each time point was calculated as the highest allergen challenge FEV1 value minus the highest saline FEV1 value. Data were adjusted for the following covariates: period, smoking status, treatment, participant-level Baseline, period-level Baseline, and treatment by smoking status interaction. (NCT01400906)
Timeframe: Day 6 of each treatment period (up to 11 weeks)
Intervention | Liters (Least Squares Mean) |
---|---|
Placebo | -0.592 |
FP 100 µg | -0.420 |
FP 500 µg | -0.431 |
FEV1 is a measure of lung function and is defined as the maximal amount of air that can be forcefully exhaled in one second. Baseline FEV1 was measured on Day 1 pre-dose administration. FEV1 was measured on Day 1 post-dose, on Day 6 (prior to allergen challenge), and on Day 7 pre dose administration. Change from Baseline was calculated as the post-Baseline value minus the Baseline value. Data were adjusted for the following covariates: period, smoking status, treatment, participant-level Baseline, period-level Baseline, and treatment by smoking status interaction. (NCT01400906)
Timeframe: Baseline, Day 1, Day 6, and Day 7
Intervention | Liters (Least Squares Mean) | |||||
---|---|---|---|---|---|---|
Day 1, Smokers, n=17, 17, 17 | Day 6, Smokers, n=16, 17, 17 | Day 7, Smokers, n=17, 17, 17 | Day 1, Non-smokers, n=16, 18, 17 | Day 6, Non-smokers, n=18, 18, 18 | Day 7, Non-smokers, n=18, 18, 18 | |
FP 100 µg | 0.216 | 0.016 | -0.083 | 0.237 | 0.114 | -0.079 |
FP 500 µg | 0.177 | 0.032 | -0.053 | 0.217 | 0.058 | 0.012 |
Placebo | 0.156 | -0.081 | -0.123 | 0.201 | -0.028 | -0.341 |
The concentration of eNO was measured on Day 6 pre-dose and on Day 7 post-study medication administration. eNO was measured 3 times at each time point, and all 3 measurements were recorded. The mean of the 3 measurements was calculated and was used in the derivation of summary statistics. (NCT01400906)
Timeframe: Day 6 and Day 7 of each treatment period (up to 11 weeks)
Intervention | Parts per billion (Mean) | |||
---|---|---|---|---|
Day 6, Pre-dose, Smokers, n=16, 17, 17 | Day 7, Post-dose, Smokers, n=17, 17, 17 | Day 6, Pre-dose, Non-smokers, n=17, 18, 18 | Day 7, Post-dose, Non-smokers, n=18, 18, 18 | |
FP 100 µg | 12.718 | 16.602 | 37.252 | 42.869 |
FP 500 µg | 14.049 | 16.298 | 32.572 | 34.989 |
Placebo | 21.117 | 45.167 | 62.980 | 98.837 |
FEV1 is a measure of lung function and is defined as the maximal amount of air that can be forcefully exhaled in one second. Participants were exposed to an allergen 1 hr after dosing on Day 6. Minimum FEV1 over 0-2 hrs post-allergen challenge (Minimum EAR) is the minimum value of all of the post-allergen challenge timepoints up to and including 2 hours post-allergen challenge (i.e., minimum over 5 minutes [min], 10 min, 15 min, 20 min, 30 min, 45 min and 1 hr, 1.5 hrs, and 2 hrs). The WM FEV1 was derived by calculating the area under the curve, and then dividing the value by the relevant time interval. Absolute change from saline at each time point was calculated as the highest allergen challenge FEV1 value minus the highest saline FEV1 value. Data were adjusted for the following covariates: period, smoking status, treatment, participant-level Baseline, period-level Baseline, and treatment by smoking status interaction. (NCT01400906)
Timeframe: Day 6 of each treatment period (up to 11 weeks)
Intervention | Liters (Least Squares Mean) | |||
---|---|---|---|---|
Minimum FEV1, Smokers, n=16, 17, 17 | Minimum FEV1, Non-smokers, n=18, 18, 18 | WM FEV1, Smokers, n=16, 17, 17 | WM FEV1, Non-smokers, n=18, 18, 18 | |
FP 100 µg | -0.769 | -0.743 | -0.303 | -0.349 |
FP 500 µg | -0.817 | -0.676 | -0.362 | -0.311 |
Placebo | -0.799 | -0.984 | -0.423 | -0.531 |
Sputum induction was performed using hypertonic saline solution to collect an adequate sample of secretions from lungs. The collected sputum was analyzed for neutrophil and eosinophil counts. Sputum induction was performed after methacholine challenge and post-dose administration on Day 7. Zero values are imputed to 0.001 for this analysis. Data were adjusted for the following covariates: period, smoking status, treatment, participant-level Baseline, period-level Baseline, and treatment by smoking status interaction. (NCT01400906)
Timeframe: Day 7 of each treatment period (up to 11 weeks)
Intervention | 10^4 cells per gram of sputum (Geometric Mean) | |||
---|---|---|---|---|
Eosinophil count, Smokers, n=7, 7, 5 | Eosinophil count, Non-smokers, n=11, 11, 10 | Neutrophil count, Smokers, n=7, 7, 5 | Neutrophil count, Non-smokers, n=11, 11, 10 | |
FP 100 µg | 0.489 | 0.878 | 50.313 | 49.532 |
FP 500 µg | 0.459 | 0.144 | 87.699 | 36.561 |
Placebo | 0.400 | 6.911 | 96.231 | 78.768 |
FEV1 is a measure of lung function and is defined as the maximal amount of air that can be forcefully exhaled in one second. Participants inhaled doubling increments of methacholine until a >=20% decrease in FEV1 from the post-saline value was achieved. (NCT01400906)
Timeframe: Day 7 of each treatment period (up to 11 weeks)
Intervention | milligrams per milliliter (Geometric Mean) | |
---|---|---|
Smokers, n=16, 17, 17 | Non smokers, n=18, 17, 18 | |
FP 100 µg | 1.233 | 1.488 |
FP 500 µg | 1.439 | 2.080 |
Placebo | 0.579 | 0.514 |
The forced expiratory volume in the first second, expressed as a percent predicted. (NCT00643578)
Timeframe: 1 hour after dose
Intervention | percent predicted (Mean) |
---|---|
12 Mcg of Formoterol | 88 |
24 Mcg of Formoterol | 91 |
The PC20 is the provocational dose of methacholine causing a 20% drop in forced expiratory volume in the first second. (NCT00643578)
Timeframe: 3-7 days after visits 1 and 2
Intervention | mg/mL (Geometric Mean) |
---|---|
12 Mcg Formoterol | 7 |
24 Mcg Formoterol | 16 |
(NCT00716963)
Timeframe: Before inhalation 3 hours
Intervention | percentage fall FEV1 (Mean) |
---|---|
Fluticasone Propionate (Flovent Diskus) 250 mcg | -30.5 |
Budesonide 400mcg | -39.0 |
Placebo | -31.9 |
(NCT00716963)
Timeframe: 7 hours after challenge
Intervention | percentage fall FEV1 (Mean) |
---|---|
Fluticasone Propionate (Flovent Diskus) 250 mcg | -11.6 |
Budesonide 400mcg | -14.7 |
Placebo | -24 |
163 reviews available for histamine and Asthma, Bronchial
Article | Year |
---|---|
Functional Profiling of 2-Aminopyrimidine Histamine H4 Receptor Modulators.
Topics: Aminopyridines; Animals; Arthritis, Rheumatoid; Asthma; Dermatitis, Atopic; Drug Partial Agonism; Hi | 2015 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Does Allergy Break Bones? Osteoporosis and Its Connection to Allergy.
Topics: Animals; Asthma; Autophagy; Bone and Bones; Cell Proliferation; Chronic Urticaria; Cytokines; Dermat | 2020 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Immune regulation by histamine and histamine-secreting bacteria.
Topics: Animals; Asthma; Gastrointestinal Microbiome; Histamine; Humans; Immunomodulation; Receptors, G-Prot | 2017 |
The Role of Histamine in the Pathophysiology of Asthma and the Clinical Efficacy of Antihistamines in Asthma Therapy.
Topics: Animals; Asthma; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Humans; Hypersensitivit | 2019 |
Efficacy of anti-interleukin-5 therapy with mepolizumab in patients with asthma: a meta-analysis of randomized placebo-controlled trials.
Topics: Anti-Asthmatic Agents; Antibodies, Monoclonal, Humanized; Asthma; Blood Cell Count; Disease Progress | 2013 |
Bronchoprovocation tests in asthma: direct versus indirect challenges.
Topics: Asthma; Bronchial Provocation Tests; Histamine; Humans; Mannitol; Methacholine Chloride; Respiratory | 2014 |
Histamine: metabolism, physiology, and pathophysiology with applications in veterinary medicine.
Topics: Animals; Asthma; Cat Diseases; Cats; Dog Diseases; Dogs; Emergencies; Histamine; Histamine Antagonis | 2009 |
Allergy, Histamine and Antihistamines.
Topics: Animals; Asthma; Eosinophils; Histamine; Histamine Antagonists; Humans; Hypersensitivity; Mast Cells | 2017 |
Leukotriene E4: perspective on the forgotten mediator.
Topics: Animals; Aspirin; Asthma; Bronchial Hyperreactivity; Drug Hypersensitivity; Histamine; Humans; Leuko | 2009 |
The role of antihistamines in the new millennium.
Topics: Asthma; Clinical Trials as Topic; Fatigue; Histamine; Histamine Antagonists; Histamine H1 Antagonist | 1999 |
Does the histamine H4 receptor have a pro- or anti-inflammatory role in murine bronchial asthma?
Topics: Animals; Asthma; Disease Models, Animal; Histamine; Humans; Indoles; Inflammation; Mice; Piperazines | 2010 |
Indirect challenge tests: Airway hyperresponsiveness in asthma: its measurement and clinical significance.
Topics: Asthma; Biomarkers; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstriction; Exe | 2010 |
Mast cells in allergic asthma and beyond.
Topics: Animals; Anti-Infective Agents; Asthma; Cytokines; Histamine; Humans; Hypersensitivity; Immune Syste | 2010 |
[Roles of histamine in the pathogenesis of bronchial asthma and reevaluation of the clinical usefulness of antihistamines].
Topics: Animals; Asthma; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Humans; Mice; Organic C | 2011 |
Histamine synthesis and lessons learned from histidine decarboxylase deficient mice.
Topics: Anaphylaxis; Animals; Asthma; Atherosclerosis; Crohn Disease; Epigenesis, Genetic; Gene Expression R | 2010 |
The role of histamine in asthma.
Topics: Animals; Asthma; Disease Models, Animal; Histamine; Histamine Antagonists; Humans; Immune System; Lu | 2010 |
Pathophysiologic role of histamine: evidence clarified by histidine decarboxylase gene knockout mice.
Topics: Anaphylaxis; Animals; Asthma; Atherosclerosis; Dermatitis, Allergic Contact; Histamine; Histidine De | 2012 |
Histamine in health and disease.
Topics: Animals; Asthma; Common Cold; Endothelium, Vascular; Histamine; Histamine Release; Humans; Hypersens | 2002 |
Role of histamine in the pathophysiology of asthma: immunomodulatory and anti-inflammatory activities of H1-receptor antagonists.
Topics: Adjuvants, Immunologic; Anti-Inflammatory Agents; Asthma; Histamine; Histamine H1 Antagonists; Human | 2002 |
Histamine decreases E-cadherin-based adhesion to increase permeability of human airway epithelium.
Topics: Animals; Asthma; Cadherins; Cell Membrane Permeability; Disease Models, Animal; Guinea Pigs; Histami | 2003 |
Bronchoprovocation methods: direct challenges.
Topics: Administration, Inhalation; Asthma; Bronchial Provocation Tests; Histamine; Humans; Methacholine Chl | 2003 |
What evidence implicates airway smooth muscle in the cause of BHR?
Topics: Actins; Animals; Asthma; Bronchi; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Dose-Respons | 2003 |
Effects of histamine on Th1/Th2 cytokine balance.
Topics: Asthma; Cytokines; Histamine; Histamine H1 Antagonists; Humans; Signal Transduction; Th1 Cells; Th2 | 2003 |
ADVANCES IN ALLERGY.
Topics: Antigen-Antibody Reactions; Asthma; Desensitization, Immunologic; Eosinophilia; Histamine; Humans; H | 1963 |
[OBSERVATIONS ON THE SYNDROME OF BRONCHIAL STENOSIS, THE MECHANISM OF ASTHMA AND ON THE BIOCHEMICAL RELATIONS IN THE ALLERGIC REACTION].
Topics: Acetylcholine; Asthma; Biochemical Phenomena; Biochemistry; Bronchial Diseases; Catecholamines; Cons | 1964 |
[CRITICAL OBSERVATION ON THE IMPORTANCE OF THE HISTAMINE-FIXING PHENOMENON WITH SPECIAL REFERENCE TO THE RESULT FROM A DERMATOLOGICAL VIEWPOINT].
Topics: Animals; Asthma; Guinea Pigs; Histamine; Hypersensitivity; Physiology; Rats; Research; Skin Diseases | 1965 |
Second-generation antihistamines in asthma therapy: is there a protective effect?
Topics: Asthma; Drug Therapy, Combination; Histamine; Histamine H1 Antagonists, Non-Sedating; Humans; Interc | 2002 |
Direct or indirect stimuli for bronchial challenge testing: what is the relevance for asthma epidemiology?
Topics: Adenosine; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstrictor Agents | 2004 |
Role of human mast cells and basophils in bronchial asthma.
Topics: Adenylyl Cyclases; Antigens, Differentiation; Asthma; Basophils; Cell Movement; Cell Proliferation; | 2005 |
Tick histamine-binding proteins and related lipocalins: potential as therapeutic agents.
Topics: Animals; Asthma; Carrier Proteins; Clinical Trials as Topic; Conjunctivitis; Histamine; Humans; Inse | 2005 |
Airway hyperresponsiveness as a determinant of the early asthmatic response to inhaled allergen.
Topics: Administration, Inhalation; Allergens; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Test | 2006 |
Progress in allergy signal research on mast cells: the role of histamine in immunological and cardiovascular disease and the transporting system of histamine in the cell.
Topics: Anaphylaxis; Animals; Asthma; Atherosclerosis; Biological Transport; Cardiovascular Diseases; Enceph | 2008 |
The mediators of bronchial asthma and the mechanism of their release.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Asthma; Biomechanical Phenomena; Calcium; Chemotactic | 1984 |
[Mediators of allergic reaction (author's transl)].
Topics: Arachidonic Acid; Arachidonic Acids; Asthma; Autacoids; Bronchial Spasm; Chemotactic Factors; Histam | 1982 |
The role of histamine and its receptors in the pathogenesis of asthma.
Topics: Animals; Asthma; Bronchi; Guinea Pigs; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists | 1983 |
Experimental asthma in guinea pigs revisited.
Topics: Anaphylaxis; Animals; Antibody Formation; Antigen-Antibody Reactions; Antigens; Asthma; Conditioning | 1984 |
[Histamine-release: present data and practical interest (author's transl)].
Topics: Adult; Aged; Asthma; Cytoplasmic Granules; Dose-Response Relationship, Drug; Drug Hypersensitivity; | 1980 |
Time-dependent processes in allergy and asthma.
Topics: Airway Obstruction; Animals; Asthma; Biological Clocks; Circadian Rhythm; Epinephrine; Guinea Pigs; | 1981 |
The airway mucociliary system.
Topics: Animals; Asthma; Autonomic Nervous System; Biological Transport; Bronchi; Bronchitis; Calcium; Cats; | 1981 |
Exercise-induced airway obstruction.
Topics: Asthma; Asthma, Exercise-Induced; Bronchi; Cold Temperature; Histamine; Humans; Hypersensitivity, Im | 1983 |
Atopic dermatitis.
Topics: Acetylcholine; Asthma; Chemotaxis, Leukocyte; Child; Child, Preschool; Dermatitis, Atopic; Female; F | 1983 |
Diagnostic procedures in allergy II. Bronchial provocation testing.
Topics: Aerosols; Allergens; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Histamine; Humans; Methac | 1983 |
Mediators and non-specific bronchial hyperreactivity.
Topics: Allergens; Animals; Asthma; Bronchi; Histamine; Humans; Prostaglandins | 1983 |
The clinical value of pharmacologic bronchoprovocation challenge.
Topics: Adolescent; Adult; Asthma; Bronchi; Bronchial Provocation Tests; Child; Dose-Response Relationship, | 1984 |
Inflammation and airway reactivity.
Topics: Aerosols; Animals; Asthma; Disease Models, Animal; Dogs; Endotoxins; Granulocytes; Guinea Pigs; Hist | 1984 |
[Inhalation provocation tests in the diagnosis of bronchial asthma].
Topics: Albuterol; Allergens; Asthma; Bronchi; Bronchial Provocation Tests; Carbachol; Evaluation Studies as | 1982 |
[Bronchial responsiveness in children with asthma--their reactions to non-specific and specific stimuli].
Topics: Acetylcholine; Adolescent; Aerosols; Airway Resistance; Asthma; Bronchial Provocation Tests; Bronchi | 1982 |
Bronchial hyperreactivity.
Topics: Animals; Asthma; Bronchi; Bronchial Diseases; Bronchial Spasm; Bronchitis; Constriction, Pathologic; | 1980 |
[Need to consider various factors predisposing to chronic nonspecific lung diseases in pre-employment orientation. Current state of the studies and research].
Topics: Acetylcholine; alpha 1-Antitrypsin Deficiency; Asthma; Bronchial Provocation Tests; Bronchitis; Clin | 1980 |
Some pharmacological aspects of xanthines in asthma.
Topics: Asthma; Histamine; Humans; Lung; Pulmonary Edema; Respiratory System; Theophylline; Xanthines | 1980 |
Airways obstruction in occupational pulmonary disease.
Topics: Asthma; Forced Expiratory Volume; Histamine; Humans; Lung Diseases, Obstructive; Occupational Diseas | 1981 |
Bronchial responsiveness to histamine or methacholine in asthma: measurement and clinical significance.
Topics: Aerosols; Albuterol; Allergens; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Cold Temperatu | 1981 |
Measurement of bronchial reactivity: a question of interpretation.
Topics: Asthma; Bronchi; Bronchial Provocation Tests; Dose-Response Relationship, Drug; Fenoterol; Histamine | 1981 |
Influence of leukotriene antagonists on baseline pulmonary function and asthmatic responses.
Topics: Antigens; Asthma; Bronchial Diseases; Cold Temperature; Constriction, Pathologic; Exercise; Histamin | 1994 |
Antihistamines in the treatment of asthma.
Topics: Allergens; Asthma; Bronchoconstriction; Histamine; Histamine H1 Antagonists; Humans; Mast Cells | 1994 |
[Transient syndrome of acute irritation of the bronchi induced by single and massive inhalation of phthalic anhydride].
Topics: Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Diagnosis, Differential; Fema | 1993 |
[Non-allergenic bronchial hyperreactivity. Measurement methods and reproducibility].
Topics: Administration, Inhalation; Airway Resistance; Asthma; Bronchial Hyperreactivity; Bronchial Provocat | 1994 |
Is airways hyperreactivity selective or non-selective?
Topics: Allergens; Asthma; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Histamine; Humans; Methacho | 1993 |
Linkage homology for bronchial hyperresponsiveness between DNA markers on human chromosome 5q31-q33 and mouse chromosome 13.
Topics: Animals; Asthma; Atracurium; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstric | 1995 |
Bronchial inhalation challenge procedures with allergens and other bronchoconstrictor substances.
Topics: Allergens; Asthma; Bronchial Provocation Tests; Bronchoconstrictor Agents; Histamine; Humans; Methac | 1996 |
[Inflammatory mediators in asthma].
Topics: Asthma; Histamine; Humans; Inflammation Mediators; Leukotrienes; Prostaglandins | 1996 |
[Pathogenesis of bronchial asthma].
Topics: Asthma; Histamine; Humans; Hypersensitivity, Immediate; Lung; Macrophages, Alveolar; Mast Cells | 1995 |
[Regulation of gene expression of L-histidine decarboxylase and histamine N-methyl-transferase, and its relevance to the pathogenesis of bronchial asthma].
Topics: Amino Acid Sequence; Animals; Asthma; Base Sequence; Gene Expression Regulation, Enzymologic; Histam | 1996 |
The role of basophils in allergic disease.
Topics: Asthma; Basophils; Bronchoalveolar Lavage Fluid; Calcium; Cell Degranulation; Chymases; Complement C | 1996 |
[Function testing of bronchial responsiveness].
Topics: Acetylcholine; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Histamine; Humans; Me | 1996 |
[Function testing of bronchial responsiveness].
Topics: Acetylcholine; Allergens; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Histamine; | 1997 |
Antihistamines in the treatment of asthma.
Topics: Asthma; Cetirizine; Clinical Trials as Topic; Histamine; Histamine H1 Antagonists; Humans | 1997 |
Testing airway responsiveness using inhaled methacholine or histamine.
Topics: Adult; Aged; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Child; Child, Preschool | 1997 |
Peripheral blood markers: evaluation of inflammation in asthma.
Topics: Asthma; Biomarkers; Blood Proteins; Cell Adhesion Molecules; Cytokines; Eicosanoids; Eosinophils; Hi | 1998 |
[Histamine in the pathogenesis of asthma].
Topics: Asthma; Histamine; Humans; Hypersensitivity, Delayed; Hypersensitivity, Immediate | 1998 |
Effect of inhaled corticosteroids on bronchial responsiveness in patients with "corticosteroid naive" mild asthma: a meta-analysis.
Topics: Administration, Inhalation; Anti-Inflammatory Agents; Asthma; Bronchial Hyperreactivity; Bronchial P | 1999 |
Challenge tests to assess airway hyperresponsiveness and efficacy of drugs used in the treatment of asthma.
Topics: Aerosols; Anti-Asthmatic Agents; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bro | 1996 |
On the role of PGD2 metabolites as markers of mast cell activation in asthma.
Topics: Animals; Asthma; Dinoprostone; Histamine; Humans; Inflammation; Mast Cells | 1999 |
Experimental models in asthma.
Topics: Adenosine; Asthma; Asthma, Exercise-Induced; Bronchoconstriction; Cold Temperature; Histamine; Human | 1999 |
Assessment of antihistamine efficacy and potency.
Topics: Asthma; Conjunctiva; Conjunctivitis; Histamine; Histamine Antagonists; Humans; Nasal Provocation Tes | 1999 |
Is antihistamine (H1-receptor antagonist) therapy useful in clinical asthma?
Topics: Asthma; Bronchi; Histamine; Histamine H1 Antagonists; Humans; Rhinitis, Allergic, Seasonal | 1999 |
Asthma mediators: current views.
Topics: Asthma; Bronchodilator Agents; Chemokines; Cytokines; Endopeptidases; Growth Substances; Histamine; | 2000 |
[Epidemiology of nonspecific bronchial hyperreactivity].
Topics: Asthma; Histamine; Humans; Respiratory Hypersensitivity | 2000 |
Bronchial hyperresponsiveness and its relationship to asthma in childhood.
Topics: Asthma; Bronchi; Bronchial Hyperreactivity; Bronchial Provocation Tests; Child; Child, Preschool; Di | 1993 |
Spirometry and tests of bronchial hyperresponsiveness in population studies.
Topics: Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstrictor Agents; Bronchodi | 2000 |
The effect of inflammation on mucociliary clearance in asthma: an overview.
Topics: Animals; Asthma; Biomarkers; Bronchitis; Chronic Disease; Histamine; Humans; Leukotrienes; Mucocilia | 2000 |
Do antihistamines have a role in asthma therapy?
Topics: Anti-Asthmatic Agents; Asthma; Bronchi; Cetirizine; Histamine; Histamine H1 Antagonists; Humans; Hyp | 2001 |
Regulation of the inflammatory response in asthma by mast cell products.
Topics: Animals; Asthma; Chemokines; Chymases; Cytokines; Histamine; Humans; Leukotrienes; Mast Cells; Prost | 2001 |
Antihistamines in the treatment of bronchial asthma. Present knowledge and future perspectives.
Topics: Asthma; Histamine; Histamine H1 Antagonists; Humans; Hypersensitivity | 2001 |
Histamine and serotonin.
Topics: Asthma; Histamine; Humans; Muscle, Smooth; Receptors, Histamine; Receptors, Serotonin; Respiratory P | 2001 |
[Pathophysiology of bronchial asthma--special reference to the role of airway epithelial cells].
Topics: Animals; Asthma; Bronchi; Bronchial Hyperreactivity; Cholinesterases; Cytokines; Eosinophils; Epithe | 2001 |
[Drug therapy of bronchial asthma].
Topics: Adrenocorticotropic Hormone; Adult; Asthma; Atropine; Beclomethasone; Child; Cromolyn Sodium; Epinep | 1975 |
Newer concepts of atopic dermatitis.
Topics: Adrenergic beta-Antagonists; Antibody Formation; Asthma; Chemotaxis; Cyclic AMP; Dermatitis, Atopic; | 1977 |
The Beta Adrenergic Theory of bronchial asthma.
Topics: Adrenergic beta-Antagonists; Asthma; Atropine; Bronchi; Bronchial Spasm; Catecholamines; DNA Replica | 1975 |
[The hypersensitive bronchial system].
Topics: Acetylcholine; Age Factors; Asthma; Bronchi; Cold Temperature; Germany, West; Histamine; Humans; Pep | 1977 |
Environmental injury of the lung: role of humoral mediators.
Topics: Acute Disease; Alveolitis, Extrinsic Allergic; Anaphylaxis; Animals; Asthma; Chronic Disease; Dogs; | 1978 |
The role of the parasymphathetic nervous system in airways disease.
Topics: Airway Resistance; Anaphylaxis; Animals; Antigen-Antibody Reactions; Asthma; Bronchial Diseases; Bro | 1975 |
Understanding atopic syndromes.
Topics: Anaphylaxis; Asthma; Chemotaxis; Dermatitis, Atopic; Eosinophils; Glucocorticoids; Histamine; Humans | 1975 |
Bronchial hyperreactivity.
Topics: Airway Obstruction; Airway Resistance; Asthma; Bradykinin; Bronchi; Bronchodilator Agents; Constrict | 1975 |
Antihistamines in the treatment of asthma.
Topics: Asthma; Bronchial Provocation Tests; Histamine; Histamine H1 Antagonists; Humans; Research Design | 1992 |
[Mediators and neuromediators in asthma].
Topics: Asthma; Atrial Natriuretic Factor; Cytokines; Histamine; Humans; Leukotrienes; Parasympathetic Nervo | 1992 |
A possible role for adhesion molecules in asthma.
Topics: Asthma; Basophils; Cell Adhesion Molecules; Cytokines; Eosinophils; Genes, Immunoglobulin; Histamine | 1992 |
The relationship of viral respiratory infections and asthma.
Topics: Antibodies, Viral; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Child; Child, Pre | 1992 |
Role of inflammatory mediators in asthma.
Topics: Asthma; Bronchi; Histamine; Humans; Lipoxygenase; Platelet Activating Factor; Prostaglandins | 1992 |
The role of histamine in allergic diseases.
Topics: Anaphylaxis; Asthma; Histamine; Histamine Release; Humans; Hypersensitivity; Rhinitis, Allergic, Sea | 1990 |
[Treatment with antihistaminic preparations].
Topics: Asthma; Drug Therapy, Combination; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Hi | 1990 |
Bronchoprovocation in children.
Topics: Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Child; Cold Temperature; Exercise Te | 1991 |
Sulphidopeptide leukotrienes in asthma.
Topics: Animals; Aspirin; Asthma; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Bronchoconstric | 1991 |
Beta-2 receptor agonists in asthma: a comparison.
Topics: Adrenergic beta-Agonists; Asthma; Asthma, Exercise-Induced; Bronchial Provocation Tests; Bronchodila | 1990 |
Histamine and asthma: an appraisal based on specific H1-receptor antagonism.
Topics: Asthma; Bronchoconstriction; Histamine; Histamine H1 Antagonists; Humans; Mast Cells | 1990 |
Antihistamines in the treatment of clinical asthma.
Topics: Animals; Asthma; Benzhydryl Compounds; Cetirizine; Dose-Response Relationship, Drug; Forced Expirato | 1990 |
Chronophysiologic determinants of asthma.
Topics: Asthma; Bronchoconstriction; Circadian Rhythm; Histamine; Humans; Hydrocortisone; Immunoglobulin E; | 1991 |
Tomorrow's asthma therapy--are antiasthmatics in the 90ties anti-inflammatory drugs?
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Asthma; Fatty Acids, Unsaturated; Histamine; Huma | 1991 |
The clinical value of pharmacologic bronchoprovocation challenge.
Topics: Asthma; Bronchial Provocation Tests; Histamine; Humans; Methacholine Chloride; Methacholine Compound | 1990 |
Mast cells and histamine in asthma.
Topics: Asthma; Biology; Histamine; Humans; Mast Cells | 1990 |
Cellular and biochemical events in the pathogenesis of asthma.
Topics: Airway Resistance; Animals; Asthma; Bronchial Spasm; Histamine; Histamine Release; Humans; Inflammat | 1986 |
[Calcium inhibitors in asthma].
Topics: Asthma; Asthma, Exercise-Induced; Calcium Channel Blockers; Histamine; Histamine Release; Humans; Me | 1987 |
Histamine and its antagonists in asthma.
Topics: Adult; Asthma; Child; Histamine; Histamine Antagonists; Histamine Release; Humans; Mast Cells | 1989 |
[Physiopathology of asthma].
Topics: Allergens; Animals; Arachidonic Acids; Asthma; Autonomic Nervous System; Basophils; Guinea Pigs; His | 1989 |
Lipid mediators of anaphylaxis and increased airways reactivity.
Topics: Anaphylaxis; Arachidonic Acids; Asthma; Bronchitis; Histamine; Humans; Leukotriene B4; Lipid Metabol | 1987 |
Pharmacology and physiology of leukotrienes and their antagonists.
Topics: Animals; Asthma; Bronchial Provocation Tests; Drug Interactions; Guinea Pigs; Histamine; Humans; Leu | 1988 |
[Intrinsic sympathomimetic action and its special features as demonstrated by the beta-1-receptor blocker celiprolol].
Topics: Adrenergic beta-Antagonists; Animals; Asthma; Blood Coagulation; Bronchi; Bronchial Spasm; Calcium C | 1985 |
Calcium, calcium channel blockade and airways function.
Topics: Adrenergic beta-Agonists; Allergens; Angina Pectoris; Animals; Asthma; Bronchi; Calcium; Calcium Cha | 1986 |
[Asthma and synthetic antihistaminics].
Topics: Animals; Asthma; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Rats | 1987 |
Anti-cholinergic agents and their use in asthma.
Topics: Allergens; Asthma; Atropine Derivatives; Bronchial Provocation Tests; Bronchial Spasm; Histamine; Hu | 1988 |
Mast cell-dependent inflammatory mediators and their putative role in bronchial asthma.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Asthma; Cell Movement; Cytoplasmic Granules; Heparin; | 1985 |
Inflammatory mechanisms and nocturnal asthma.
Topics: Adenosine; Asthma; Blood Platelets; Circadian Rhythm; Eosinophils; Epithelium; Histamine; Humans; In | 1988 |
Bronchial hyperresponsiveness is not bronchial hyperresponsiveness is not bronchial asthma.
Topics: Acetylcholine; Adenosine; Airway Resistance; Animals; Asthma; Bronchi; Histamine; Humans; Methacholi | 1988 |
The interaction of histamine with other bronchoconstrictor mediators.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Asthma; Bronchi; Histamine; Humans; Muscle Contraction | 1987 |
[Mediators of immunologic inflammation of the respiratory tract].
Topics: Allergens; Arachidonic Acid; Arachidonic Acids; Asthma; Blood Platelets; Bronchial Provocation Tests | 1988 |
Modulation of airway hyperresponsiveness.
Topics: Acetylcholine; Airway Resistance; Asthma; Carbachol; Histamine; Humans; Methacholine Compounds; Prop | 1988 |
Histamine and airway caliber.
Topics: Animals; Asthma; Histamine; Histamine Antagonists; Humans; Parasympathetic Nervous System; Receptors | 1988 |
Vitamin C and airways.
Topics: Adrenal Glands; Animals; Ascorbic Acid; Asthma; Histamine; Humans; Lung; Prostaglandins | 1987 |
Mediators and mucociliary clearance in asthma.
Topics: Animals; Asthma; Histamine; Humans; Mucociliary Clearance; Prostaglandins; SRS-A | 1987 |
In-vivo and in-vitro responsiveness of bronchial smooth muscle.
Topics: Airway Resistance; Albuterol; Animals; Asthma; Atropine; Atropine Derivatives; Bronchi; Carbachol; D | 1986 |
Does measurement of bronchial hyperreactivity help in the clinical diagnosis of asthma?
Topics: Airway Resistance; Asthma; Bronchi; Bronchial Provocation Tests; Histamine; Humans; Lung Diseases, O | 1986 |
The origin of airway hyperresponsiveness.
Topics: Allergens; Asthma; Autonomic Nervous System; Epithelium; Histamine; Humans; Methacholine Chloride; M | 1986 |
Histamine and asthma.
Topics: Asthma; Histamine; Humans; Receptors, Histamine | 1987 |
Provoked asthma and mast cells.
Topics: Asthma; Asthma, Exercise-Induced; Histamine; Humans; Mast Cells | 1987 |
The role of histamine and other mediators in microvascular changes in acute inflammation.
Topics: Animals; Asthma; Histamine; Humans; Inflammation; Lung; Microcirculation; Microscopy, Electron; Neut | 1987 |
Mast cell mediators in the blood of patients with asthma.
Topics: Adenosine; Antigens; Asthma; Bronchial Spasm; Chemotactic Factors; Histamine; Humans; Mast Cells; Pl | 1985 |
Heterogeneity of mechanisms in exercise induced asthma.
Topics: Asthma; Asthma, Exercise-Induced; Body Temperature Regulation; Bronchi; Chemotactic Factors; Histami | 1985 |
Bronchial inhalation tests. I. Measurement of nonallergic bronchial responsiveness.
Topics: Administration, Intranasal; Aerosols; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Dose-Res | 1985 |
[Determinants of bronchial hypersensitivity].
Topics: Airway Resistance; Animals; Asthma; Bronchi; Circadian Rhythm; Heart Failure; Histamine; Humans; Hyp | 1985 |
The pharmacology of asthma and possible therapeutic developments.
Topics: Animals; Anti-Inflammatory Agents; Antibody Formation; Antigen-Antibody Reactions; Asthma; Blood Pla | 1971 |
Abnormal autonomic merchanisms in asthma.
Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Animals; Asthma; Cyclic GMP; DNA; Epinephrine; Hista | 1974 |
Bronchopulmonary diseases. Immunologic perspectives.
Topics: Allergens; Anti-Glomerular Basement Membrane Disease; Antigen-Antibody Reactions; Asthma; Bronchi; B | 1973 |
Autonomic imbalance in asthma with special reference to beta adrenergic blockade.
Topics: Acetylcholine; Adenylyl Cyclases; Adrenergic alpha-Antagonists; Animals; Asthma; Blood Glucose; Brad | 1972 |
Antiasthmatic drugs I: pathophysiological and clinical pharmacological aspects.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Albuterol; Amines; Asthma; Autacoids; Bradykin | 1974 |
Sodium cromoglycate (cromolyn sodium): a review of its mode of action, pharmacology, therapeutic efficacy and use.
Topics: Action Potentials; Administration, Intranasal; Adrenal Cortex Hormones; Adult; Age Factors; Airway O | 1974 |
[Drug effect on the smooth muscle of the bronchi. (Collective review as a contribution to the study of antiasthmatic preparations)].
Topics: Acetylcholine; Animals; Asthma; Bronchodilator Agents; Histamine; Histamine H1 Antagonists; Humans; | 1969 |
Corticosteroids and allergy.
Topics: Adrenal Cortex Hormones; Anaphylaxis; Animals; Antibody Formation; Antigen-Antibody Reactions; Asthm | 1969 |
Endogenous broncho-active substances and their antagonism.
Topics: Anaphylaxis; Animals; Anti-Inflammatory Agents; Aspirin; Asthma; Bradykinin; Bronchi; Drug Antagonis | 1970 |
Disodium cromoglycate. Mode of action and its possible relevance to the clinical use of the drug.
Topics: Adrenergic alpha-Agonists; Aerosols; Animals; Antibodies; Antigens; Asthma; Cell Membrane; Chromones | 1971 |
Distribution of histamine in human blood.
Topics: Asthma; Basophils; Histamine; Humans; Hypersensitivity; Infant, Newborn; Leukocytes; Methods; Protei | 1972 |
[Role of biologically active substances in the pathogenesis of experimental allergy and bronchial asthma (literature review)].
Topics: Acetylcholine; Anaphylaxis; Animals; Asthma; Cholinesterases; Dogs; Guinea Pigs; Heparin; Histamine; | 1972 |
Mast cells and allergic asthma.
Topics: Animals; Antibodies; Antigens; Asthma; Bronchi; Cell Membrane; Cell Nucleus; Collagen; Cytoplasmic G | 1973 |
[A comparison of allergic bronchial asthma and other obstructive respiratory diseases (author's transl)].
Topics: Acetylcholine; Allergens; Asthma; Diagnosis, Differential; Dust; Dyspnea, Paroxysmal; Flour; Histami | 1974 |
[What is known today about the immunology and biochemistry of asthma? Immunologic reaction in asthma].
Topics: Adenylyl Cyclases; Allergens; Aspirin; Asthma; Bronchi; Desensitization, Immunologic; Drug Hypersens | 1974 |
Immunopharmacological aspects of bronchial asthma.
Topics: Anaphylaxis; Animals; Antigen-Antibody Reactions; Asthma; Basophils; Bronchi; Cromolyn Sodium; Cycli | 1973 |
Allergic asthma in childhood.
Topics: Adult; Allergens; Asthma; Bronchi; Bronchial Spasm; Child; Dust; Fungi; Histamine; Humans; Hypersens | 1969 |
[The autonomic nervous system and respiration].
Topics: Asthma; Autonomic Nervous System; Bronchitis; Histamine; Kinins; Neurons, Afferent; Neurons, Efferen | 1971 |
[Diagnostic possibilities in the asthma-syndrome in childhood].
Topics: Acetylcholine; Asthma; Bronchitis; Child; Child, Preschool; Diagnosis, Differential; Drug Hypersensi | 1971 |
[Role of the autonomic nervous system in pathogenesis of allergy].
Topics: Acetylcholine; Adolescent; Adult; Aged; Animals; Antibody Formation; Asthma; Autonomic Nervous Syste | 1971 |
[Clinical forms and physiopathology of bronchial asthma in the light of present-day views].
Topics: Age Factors; Asthma; Bacterial Infections; Bronchi; Chronic Disease; Histamine; Humans; Immunoglobul | 1971 |
Cardiac manifestations due to hypersensitivity.
Topics: Adams-Stokes Syndrome; Anaphylaxis; Angina Pectoris; Antigen-Antibody Complex; Arrhythmias, Cardiac; | 1970 |
378 trials available for histamine and Asthma, Bronchial
Article | Year |
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Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
The Impact of Food Histamine Intake on Asthma Activity: A Pilot Study.
Topics: Asthma; Child; Diet; Feeding Behavior; Female; Food; Histamine; Humans; Male; Micronutrients; Pilot | 2020 |
Low-dose salbutamol suppresses airway responsiveness to histamine but not methacholine in subjects with asthma.
Topics: Administration, Inhalation; Adolescent; Adrenergic beta-2 Receptor Agonists; Adult; Aged; Albuterol; | 2013 |
Differences in effects of omalizumab on late-phase responses to allergen challenge in the skin and nose at the time of basophil hyporesponsiveness.
Topics: Allergens; Animals; Anti-Allergic Agents; Antibodies, Anti-Idiotypic; Antibodies, Monoclonal, Humani | 2014 |
Airways resistance in bronchial challenge testing.
Topics: Adult; Airway Resistance; Asthma; Female; Forced Expiratory Volume; Histamine; Humans; Male; Middle | 2015 |
Intranasal corticosteroid administration reduces nonspecific bronchial hyperresponsiveness and improves asthma symptoms.
Topics: Administration, Intranasal; Adolescent; Adult; Asthma; Beclomethasone; Bronchial Hyperreactivity; Do | 2008 |
Adverse effects of salmeterol in asthma: a neuronal perspective.
Topics: Adolescent; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Adult; Albuterol; Androst | 2009 |
Unaffected peak inspiratory flow through Turbuhaler during histamine inhalation challenge.
Topics: Administration, Inhalation; Asthma; Bronchial Provocation Tests; Budesonide; Child; Dry Powder Inhal | 2011 |
Budesonide/formoterol maintenance and reliever therapy in primary care asthma management: effects on bronchial hyperresponsiveness and asthma control.
Topics: Adrenal Cortex Hormones; Adult; Anti-Asthmatic Agents; Asthma; Budesonide; Budesonide, Formoterol Fu | 2012 |
Effects of hydrocortisone on acute β-adrenoceptor blocker and histamine induced bronchoconstriction.
Topics: Administration, Inhalation; Adrenergic beta-Antagonists; Adult; Albuterol; Anti-Inflammatory Agents; | 2012 |
Predicting asthma treatment outcome at diagnosis: the role of symptom perception during a histamine challenge test.
Topics: Adult; Albuterol; Asthma; Bronchial Provocation Tests; Diagnostic Self Evaluation; Female; Forced Ex | 2012 |
Sensitivity of impulse oscillometry and spirometry in beta-blocker induced bronchoconstriction and beta-agonist bronchodilatation in asthma.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Airway Resistance; Albuterol; Asthma; | 2012 |
Clinical evaluation of the effect of anti-allergic mattress covers in patients with moderate to severe asthma and house dust mite allergy: a randomised double blind placebo controlled study.
Topics: Adolescent; Adult; Allergens; Animals; Asthma; Bedding and Linens; Bronchial Hyperreactivity; Child; | 2002 |
Rapid effect of inhaled fluticasone propionate on airway responsiveness to adenosine 5'-monophosphate in mild asthma.
Topics: Adenosine Monophosphate; Administration, Inhalation; Adult; Androstadienes; Anti-Inflammatory Agents | 2002 |
Clinical effects of air filters in homes of asthmatic adults sensitized and exposed to pet allergens.
Topics: Adult; Air Conditioning; Air Pollution, Indoor; Allergens; Animals; Animals, Domestic; Asthma; Bronc | 2003 |
Responsiveness to three bronchial provocation tests in patients with asthma.
Topics: Adult; Aged; Asthma; Bronchial Provocation Tests; Cold Temperature; Female; Histamine; Humans; Logis | 2003 |
Randomized controlled trial of unflued gas heater replacement on respiratory health of asthmatic schoolchildren.
Topics: Air Pollutants; Air Pollution, Indoor; Asthma; Bronchial Provocation Tests; Child; Female; Forced Ex | 2004 |
Spirometry and forced oscillometry assisted optimal frequency band determination for the computerized analysis of tracheal lung sounds in asthma.
Topics: Adult; Airway Obstruction; Algorithms; Asthma; Auscultation; Diagnosis, Computer-Assisted; Female; F | 2004 |
Effects of long-acting bronchodilators and placebo on histamine-induced asthma symptoms and mild bronchusobstruction.
Topics: Adult; Albuterol; Asthma; Bronchoconstriction; Bronchodilator Agents; Delayed-Action Preparations; D | 2006 |
Effect of histamine and adenosine 5'-monophosphate provocation on sputum neutrophils and related mediators in atopic patients.
Topics: Adenosine Monophosphate; Adult; Asthma; Bronchial Provocation Tests; Cell Count; Cross-Over Studies; | 2005 |
Beclomethasone dipropionate attenuates airways hyperresponsiveness to neurokinin A and histamine in asthma.
Topics: Administration, Inhalation; Adrenal Cortex Hormones; Adrenergic beta-Agonists; Adult; Albuterol; Ana | 2006 |
Interpretation of cough provoked by airway challenges.
Topics: Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstriction; Cough; Forced E | 2005 |
Effect of montelukast on basophil releasability in patients with asthma.
Topics: Acetates; Adult; Asthma; Basophils; Cyclopropanes; Cysteine; Female; Histamine; Humans; Immunologic | 2005 |
Stronger nasal responsiveness to cold air in individuals with rhinitis and asthma, compared with rhinitis alone.
Topics: Adult; Aged; Analysis of Variance; Asthma; Cold Temperature; Enzyme-Linked Immunosorbent Assay; Fema | 2006 |
Determinants of the bronchodilation response to salbutamol on histamine-induced bronchoconstriction.
Topics: Administration, Inhalation; Adrenergic beta-Agonists; Adult; Albuterol; Asthma; Bronchi; Bronchocons | 2006 |
Polymorphisms in eosinophil pathway genes, asthma and atopy.
Topics: Adolescent; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Child; Child, Preschool; | 2007 |
Swimming and persons with mild persistant asthma.
Topics: Adrenergic beta-Agonists; Adult; Albuterol; Asthma; Beclomethasone; Bronchial Hyperreactivity; Femal | 2007 |
Salmeterol plus fluticasone propionate versus fluticasone propionate plus montelukast: a randomised controlled trial investigating the effects on airway inflammation in asthma.
Topics: Acetates; Adrenergic beta-Agonists; Adult; Albuterol; Androstadienes; Anti-Asthmatic Agents; Asthma; | 2007 |
Occupational asthma to ivy (Hedera helix).
Topics: Adult; Allergens; Antigens, Plant; Asthma; Bronchial Provocation Tests; Female; Forced Expiratory Vo | 2008 |
Effect of disease duration on dose-response of inhaled budesonide in asthma.
Topics: Administration, Inhalation; Adolescent; Adult; Asthma; Bronchodilator Agents; Budesonide; Dose-Respo | 2008 |
Histamine-induced bronchospasm. Its reproducibility and usage in clinical evaluation of the sub-threshold bronchodilating dose of a new beta-agonist, KWD 2131.
Topics: Adrenergic beta-Agonists; Adult; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Bronchodilato | 1980 |
A comparison of the actions of H1 and H2 antihistamines on histamine-induced bronchoconstriction and cutaneous wheal response in asthmatic patients.
Topics: Asthma; Bronchial Provocation Tests; Bronchial Spasm; Chlorpheniramine; Cimetidine; Clinical Trials | 1981 |
Evaluation of the bronchodilating and antiallergic properties of a beta-adrenoceptor stimulant, KWD 2131, in asthmatic patients.
Topics: Adrenergic beta-Antagonists; Adult; Allergens; Asthma; Bronchodilator Agents; Chronic Disease; Clini | 1980 |
Prazosin, an alpha 1-adrenoceptor antagonist, partially inhibits exercise-induced asthma.
Topics: Adolescent; Adrenergic alpha-Agonists; Asthma; Asthma, Exercise-Induced; Child; Clinical Trials as T | 1981 |
Influence of intrinsic sympathomimetic activity (ISA) during beta-adrenoceptor blockade in asthmatics.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Asthma; Female; Forced Expiratory Volume; Histamine; Human | 1982 |
Vasoactive intestinal peptide causes bronchodilatation and protects against histamine-induced bronchoconstriction in asthmatic subjects.
Topics: Adult; Asthma; Bronchi; Bronchodilator Agents; Double-Blind Method; Female; Forced Expiratory Volume | 1983 |
Arterial plasma histamine levels at rest, and during and after exercise in patients with asthma: effects of terbutaline aerosol.
Topics: Adult; Aerosols; Asthma; Asthma, Exercise-Induced; Cyclic AMP; Forced Expiratory Volume; Histamine; | 1981 |
Effect of negative ionisation of inspired air on the response of asthmatic children to exercise and inhaled histamine.
Topics: Adolescent; Adult; Air Ionization; Asthma; Asthma, Exercise-Induced; Bronchial Provocation Tests; Ch | 1983 |
The protective effect of inhaled chlorpheniramine and atropine on bronchoconstriction stimulated by airway cooling.
Topics: Adult; Asthma; Atropine; Bronchi; Bronchial Provocation Tests; Chlorpheniramine; Clinical Trials as | 1983 |
Nifedipine in the prevention of asthma induced by exercise and histamine.
Topics: Asthma; Asthma, Exercise-Induced; Clinical Trials as Topic; Double-Blind Method; Forced Expiratory V | 1983 |
Variable inhibition of histamine-induced bronchoconstriction by atropine in subjects with asthma.
Topics: Adult; Asthma; Atropine; Bronchial Spasm; Clinical Trials as Topic; Dose-Response Relationship, Drug | 1984 |
Oral tartrazine challenge in childhood asthma: effect on bronchial reactivity.
Topics: Adolescent; Asthma; Azo Compounds; Bronchi; Child; Clinical Trials as Topic; Double-Blind Method; Fe | 1984 |
Effects of theophylline on inhaled methacholine and histamine in asthmatic children.
Topics: Adolescent; Asthma; Bronchi; Bronchial Provocation Tests; Child; Female; Histamine; Humans; Male; Me | 1984 |
Protective effect of circulating epinephrine within the physiologic range on the airway response to inhaled histamine in nonasthmatic subjects.
Topics: Administration, Intranasal; Adult; Airway Resistance; Asthma; Blood Pressure; Clinical Trials as Top | 1984 |
Effect of sodium cromoglycate on histamine inhalation tests.
Topics: Adult; Asthma; Bronchial Provocation Tests; Clinical Trials as Topic; Cromolyn Sodium; Female; Force | 1984 |
Cromolyn modifies histamine bronchial reactivity in symptomatic seasonal asthma.
Topics: Adolescent; Adult; Aged; Airway Resistance; Asthma; Bronchial Provocation Tests; Cromolyn Sodium; Fe | 1984 |
The effect of ipratropium and fenoterol on methacholine-histamine-induced bronchoconstriction.
Topics: Adolescent; Adult; Aged; Asthma; Atropine Derivatives; Bronchial Provocation Tests; Double-Blind Met | 1981 |
The effect of inhaled vasoactive intestinal peptide on bronchial reactivity to histamine in humans.
Topics: Adult; Aerosols; Airway Resistance; Asthma; Bronchi; Bronchial Provocation Tests; Female; Forced Exp | 1984 |
The effect of atropine on allergen-induced increases in bronchial responsiveness to histamine.
Topics: Adult; Aerosols; Airway Resistance; Allergens; Asthma; Atropine; Bronchi; Dose-Response Relationship | 1984 |
Effect of inhaled diphemanil methylsulfate, a parasympatholytic agent, on histamine induced bronchoconstriction in asymptomatic asthmatics.
Topics: Administration, Intranasal; Adult; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Bronchodila | 1984 |
Studies on histamine metabolism in allergen-induced asthma.
Topics: Adolescent; Adult; Allergens; Asthma; Bronchial Provocation Tests; Cromolyn Sodium; Female; Forced E | 1980 |
Effect of nifedipine on bronchomotor tone and histamine reactivity in asthma.
Topics: Adult; Asthma; Bronchial Provocation Tests; Histamine; Humans; Middle Aged; Nifedipine; Pyridines; R | 1981 |
Bronchial hyperreactivity in response to inhalation of ultrasonically nebulised solutions of distilled water and saline.
Topics: Adolescent; Adult; Aerosols; Asthma; Bronchi; Bronchial Provocation Tests; Forced Expiratory Volume; | 1981 |
Objective test for food sensitivity in asthmatic children: increased bronchial reactivity after cola drinks.
Topics: Adolescent; Asthma; Beverages; Bronchial Provocation Tests; Carbonated Beverages; Child; Female; Foo | 1982 |
Effect of nifedipine on histamine reactivity in asthma.
Topics: Adolescent; Adult; Asthma; Bronchi; Double-Blind Method; Female; Forced Expiratory Volume; Histamine | 1982 |
Prostaglandins and the control of airways responses to histamine in normal and asthmatic subjects.
Topics: Adult; Airway Resistance; Albuterol; Asthma; Bronchial Provocation Tests; Dose-Response Relationship | 1983 |
Protective effect of inhaled salbutamol powder in children assessed by histamine challenge.
Topics: Adolescent; Albuterol; Asthma; Bronchial Provocation Tests; Child; Clinical Trials as Topic; Double- | 1980 |
A calcium antagonist, nifedipine, modifies exercise-induced asthma.
Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Bronchial Provocation Tests; Calcium Channel Bl | 1981 |
Effect of orally administered cimetidine on histamine- and antigen-induced bronchospasm in subjects with asthma.
Topics: Adult; Airway Resistance; Antigens; Asthma; Bronchi; Bronchial Provocation Tests; Cimetidine; Female | 1982 |
Histamine blocking agents in healthy and asthmatic subjects.
Topics: Asthma; Bronchi; Bronchial Spasm; Chlorpheniramine; Cimetidine; Forced Expiratory Flow Rates; Guanid | 1982 |
Effects of infused histamine on asthmatic and normal subjects: comparison of skin test responses.
Topics: Adolescent; Adult; Asthma; Female; Histamine; Humans; Male; Middle Aged; Receptors, Histamine H1; Re | 1981 |
[The effect of loratadine on skin and bronchial reactivity and histamine liberation from basophils in patients with atopic asthma and allergic rhinitis].
Topics: Asthma; Basophils; Bronchial Provocation Tests; Histamine; Histamine Release; Humans; Loratadine; Rh | 1994 |
Repeated inhalation challenge with exogenous and endogenous histamine released by acetaldehyde inhalation in asthmatic patients.
Topics: Acetaldehyde; Administration, Inhalation; Adult; Aged; Asthma; Bronchial Hyperreactivity; Bronchial | 1995 |
Effect of procaterol, a beta 2-adrenoceptor agonist, on skin whealing response caused by inflammatory mediators in asthmatic children.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Bradykinin; Child; Cross-Over Studies; | 1995 |
Effect of zatebradine, a novel 'sinus node inhibitor', on pulmonary function compared to placebo.
Topics: Adolescent; Adult; Aged; Albuterol; Asthma; Benzazepines; Bronchial Hyperreactivity; Cardiovascular | 1994 |
Cross refractoriness between bradykinin and hypertonic saline challenges in asthma.
Topics: Adolescent; Adult; Asthma; Bradykinin; Bronchial Provocation Tests; Dose-Response Relationship, Drug | 1995 |
[Effect of loratadine, selective antagonist of histamine H1 receptors, on histamine-induced bronchoconstriction].
Topics: Adult; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Drug Administration Schedule; Femal | 1995 |
Inhaled lysine acetylsalicylate (L-ASA) attenuates the bronchoconstrictor response to adenosine 5'-monophosphate (AMP) in asthmatic subjects.
Topics: Adenosine Monophosphate; Administration, Inhalation; Adult; Analysis of Variance; Anti-Inflammatory | 1995 |
Effect of an inhaled neutral endopeptidase inhibitor, phosphoramidon, on baseline airway calibre and bronchial responsiveness to bradykinin in asthma.
Topics: Administration, Inhalation; Adult; Aerosols; Asthma; Bradykinin; Bronchi; Bronchial Provocation Test | 1995 |
Bronchodilator subsensitivity to salbutamol after twice daily salmeterol in asthmatic patients.
Topics: Acute Disease; Adrenergic beta-Agonists; Adult; Albuterol; Asthma; Bronchial Provocation Tests; Cros | 1995 |
Effect of an alpha 2-adrenoceptor antagonist, midaglizole, on bronchial responsiveness to histamine in patients with mild asthma.
Topics: Administration, Oral; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adult; Asthma; Bronchi | 1995 |
Inhaled indomethacin prevents bronchoconstrictive response to distilled water but not to histamine in children with asthma.
Topics: Administration, Inhalation; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Child; Cross-O | 1995 |
Relationship between ultrasonically nebulized distilled water-induced bronchoconstriction and acetic acid-induced cough in asthmatic children.
Topics: Acetates; Acetic Acid; Adolescent; Asthma; Bronchoconstriction; Child; Cough; Female; Furosemide; Hi | 1995 |
Differences in aerosol output and airways responsiveness between the DeVilbiss 40 and 45 hand held nebulisers.
Topics: Adult; Aerosols; Asthma; Bronchial Provocation Tests; Dose-Response Relationship, Drug; Drug Adminis | 1995 |
A comparison of a single-step cold-dry air challenge and a routine histamine provocation for the assessment of bronchial responsiveness in children and adolescents.
Topics: Adolescent; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Child; Cold Temperature; | 1995 |
Inhaled nedocromil sodium reduces histamine release from isolated large airway segments of asthmatic subjects in vivo.
Topics: Administration, Inhalation; Adult; Aerosols; Asthma; Bronchi; Bronchoconstriction; Bronchoscopy; Cat | 1993 |
Effects of pretreatment with inhaled methoxamine on bronchial responses to histamine in asthmatic subjects.
Topics: Administration, Inhalation; Adult; Asthma; Bronchi; Bronchial Provocation Tests; Bronchoconstriction | 1995 |
Effect of inhaled atrial natriuretic peptide and a neutral endopeptidase inhibitor on histamine-induced bronchoconstriction.
Topics: Administration, Inhalation; Adult; Asthma; Atrial Natriuretic Factor; Bronchial Provocation Tests; B | 1995 |
Roxithromycin reduces the degree of bronchial hyperresponsiveness in children with asthma.
Topics: Adolescent; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Child; Female; Histamine | 1994 |
Effect of altitude on urinary leukotriene (LT) E4 excretion and airway responsiveness to histamine in children with atopic asthma.
Topics: Adolescent; Altitude; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Child; Eosinop | 1995 |
The effect of 1 ppm nitrogen dioxide on bronchoalveolar lavage cells and inflammatory mediators in normal and asthmatic subjects.
Topics: Adult; Asthma; Bronchoalveolar Lavage Fluid; Bronchoscopy; Exercise Test; Female; Forced Expiratory | 1995 |
Direct evidence for a role of the mast cell in the nasal response to aspirin in aspirin-sensitive asthma.
Topics: Adult; Aspirin; Asthma; Blood Proteins; Chymases; Cross-Over Studies; Double-Blind Method; Eosinophi | 1994 |
The effect of MK-0591, a novel 5-lipoxygenase activating protein inhibitor, on leukotriene biosynthesis and allergen-induced airway responses in asthmatic subjects in vivo.
Topics: 5-Lipoxygenase-Activating Proteins; Administration, Oral; Adult; Allergens; Asthma; Bronchial Hyperr | 1995 |
Comparison of two epidemiological protocols for measuring airway responsiveness and allergic sensitivity in adults.
Topics: Adolescent; Adult; Allergens; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Female | 1994 |
Comparison of the effects of salbutamol and adrenaline on airway smooth muscle contractility in vitro and on bronchial reactivity in vivo.
Topics: Adult; Albuterol; Asthma; Bronchoconstriction; Cross-Over Studies; Culture Techniques; Dose-Response | 1994 |
Theophylline attenuation of airway responses to allergen: comparison with cromolyn metered-dose inhaler.
Topics: Adolescent; Adult; Allergens; Asthma; Bronchi; Cromolyn Sodium; Cross-Over Studies; Double-Blind Met | 1995 |
Bronchoprotection by salmeterol: cell stabilization or functional antagonism? Comparative effects on histamine- and AMP-induced bronchoconstriction.
Topics: Adenosine Monophosphate; Adult; Albuterol; Asthma; Bronchi; Bronchial Provocation Tests; Bronchocons | 1994 |
No effect of the oral neutral endopeptidase inhibitor candoxatril, on bronchomotor tone and histamine reactivity in asthma.
Topics: Administration, Oral; Adult; Analysis of Variance; Asthma; Atrial Natriuretic Factor; Blood Pressure | 1994 |
[Inhalation corticosteroid therapy and nonspecific bronchial responsiveness enhanced with salbutamol].
Topics: Administration, Inhalation; Adolescent; Adult; Albuterol; Asthma; Bronchial Provocation Tests; Hista | 1994 |
Effect of regular terbutaline and budesonide on bronchial reactivity to allergen challenge.
Topics: Adolescent; Adult; Allergens; Asthma; Bronchi; Bronchial Provocation Tests; Budesonide; Dose-Respons | 1994 |
Effect of inhaled bradykinin on indices of airway responsiveness in asthmatic subjects.
Topics: Administration, Inhalation; Adolescent; Adult; Asthma; Bradykinin; Bronchial Provocation Tests; Bron | 1994 |
[Bronchial hypersensitivity and development of bronchial asthma in children with atopic dermatitis].
Topics: Age of Onset; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Child; Child, Preschoo | 1994 |
[Bronchial hypersensitivity to histamine in asthmatic children longitudinal study from first visit to remitted state].
Topics: Adolescent; Adult; Age of Onset; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Chi | 1994 |
Immediate-type hypersensitivity reactions and hypnosis: problems in methodology.
Topics: Adolescent; Adult; Arousal; Asthma; Female; Histamine; Humans; Hypersensitivity, Immediate; Hypnosis | 1994 |
The comparative actions and adverse effect profile of single doses of H1-receptor antihistamines in the airways and skin of subjects with asthma.
Topics: Adult; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Female; Forced Expiratory Volume; H | 1993 |
The effect of H1-receptor blockade on the development of early- and late-phase bronchoconstriction and increased bronchial responsiveness in allergen-induced asthma.
Topics: Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstriction; Double-B | 1993 |
The effect of salmeterol on the early- and late-phase reaction to bronchial allergen and postchallenge variation in bronchial reactivity, blood eosinophils, serum eosinophil cationic protein, and serum eosinophil protein X.
Topics: Adrenergic beta-Agonists; Adult; Albuterol; Allergens; Asthma; Blood Proteins; Bronchial Provocation | 1993 |
Asthma control during and after cessation of regular beta 2-agonist treatment.
Topics: Administration, Inhalation; Adrenergic beta-Agonists; Adult; Albuterol; Analysis of Variance; Asthma | 1993 |
Effect of oral terfenadine on bronchoconstrictor response to inhaled neurokinin A and histamine in asthmatic subjects.
Topics: Administration, Oral; Adolescent; Adult; Asthma; Bronchial Provocation Tests; Bronchoconstriction; B | 1993 |
Decrease of histamine induced bronchoconstriction by caffeine in mild asthma.
Topics: Adult; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Caffeine; Double-Blind Method; Fema | 1993 |
Effect of preservative on the efficacy of terbutaline nebuliser solution in atopic asthma.
Topics: Administration, Inhalation; Adult; Asthma; Bronchoconstriction; Double-Blind Method; Female; Forced | 1993 |
Exercise, regardless of induced bronchoconstriction or inspired air conditions, does not alter airway reactivity.
Topics: Adolescent; Air; Asthma; Bronchi; Bronchial Provocation Tests; Bronchoconstriction; Child; Cold Temp | 1993 |
Factors determining bradykinin bronchial responsiveness and refractoriness in asthma.
Topics: Adult; Asthma; Bradykinin; Bronchial Hyperreactivity; Bronchial Provocation Tests; Double-Blind Meth | 1993 |
The protective effect of inhaled levomepromazine (Nozinan) on histamine-induced bronchial constriction.
Topics: Administration, Inhalation; Adolescent; Adult; Asthma; Dose-Response Relationship, Drug; Double-Blin | 1993 |
Oral leukotriene inhibitor (MK-886) blocks allergen-induced airway responses.
Topics: Administration, Oral; Adult; Allergens; Asthma; Bronchial Provocation Tests; Double-Blind Method; Dr | 1993 |
Differential effects of fluticasone propionate on allergen-evoked bronchoconstriction and increased urinary leukotriene E4 excretion.
Topics: Administration, Inhalation; Administration, Topical; Adult; Allergens; Androstadienes; Anti-Inflamma | 1993 |
The effect of nedocromil sodium on histamine responsiveness in clinically stable asthmatic children.
Topics: Adolescent; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Child; Double-Blind Meth | 1993 |
Preventive effects of beclomethasone on histamine-induced changes in breathing pattern in asthma.
Topics: Adolescent; Adult; Asthma; Beclomethasone; Bronchial Hyperreactivity; Bronchial Provocation Tests; F | 1993 |
Duration of effect of loratadine and terfenadine administered once a day for one week on cutaneous and inhaled reactivity to histamine.
Topics: Administration, Inhalation; Adult; Aged; Asthma; Bronchoconstriction; Dose-Response Relationship, Dr | 1993 |
Dietary fish oil effects on seasonal hay fever and asthma in pollen-sensitive subjects.
Topics: Adult; Asthma; Bronchial Provocation Tests; Docosahexaenoic Acids; Double-Blind Method; Drug Combina | 1993 |
Effect of an oral potassium channel activator, BRL 38227, on airway function and responsiveness in asthmatic patients: comparison with oral salbutamol.
Topics: Adult; Asthma; Benzopyrans; Bronchodilator Agents; Cromakalim; Double-Blind Method; Female; Forced E | 1993 |
Cross-tachyphylactic airway response to inhaled bradykinin, kallidin and [desArg9]-bradykinin in asthmatic subjects.
Topics: Administration, Inhalation; Adult; Asthma; Bradykinin; Bronchial Provocation Tests; Bronchoconstrict | 1993 |
Comparing methods for assessing bronchial responsiveness in children: single step cold air challenge, multiple step cold air challenge, and histamine provocation.
Topics: Adolescent; Adult; Air; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Child; Cold | 1995 |
Surfactant nebulization does not alter airflow obstruction and bronchial responsiveness to histamine in asthmatic children.
Topics: Adolescent; Aerosols; Airway Obstruction; Animals; Asthma; Bronchial Provocation Tests; Bronchoconst | 1996 |
Comparison of addition of salmeterol to inhaled steroids with doubling of the dose of inhaled steroids.
Topics: Administration, Inhalation; Adolescent; Adrenergic beta-Agonists; Adult; Aged; Albuterol; Anti-Asthm | 1996 |
The respiratory effects of reduction of mite allergen in the bedrooms of asthmatic children--a double-blind controlled trial.
Topics: Allergens; Asthma; Bedding and Linens; Bronchial Hyperreactivity; Bronchial Provocation Tests; Child | 1996 |
Increased urinary excretion of the prostaglandin D2 metabolite 9 alpha, 11 beta-prostaglandin F2 after aspirin challenge supports mast cell activation in aspirin-induced airway obstruction.
Topics: Adult; Airway Obstruction; Allergens; Aspirin; Asthma; Bronchial Provocation Tests; Chromatography, | 1996 |
Histamine in wine. Bronchoconstriction after a double-blind placebo-controlled red wine provocation test.
Topics: Adult; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Double-Blind Method; Female; Histam | 1996 |
Inhaled lysine acetylsalicylate (L-ASA) attenuates histamine-induced bronchoconstriction in asthma.
Topics: Administration, Inhalation; Adult; Aspirin; Asthma; Bronchoconstriction; Cyclooxygenase Inhibitors; | 1996 |
Rush immunotherapy with house dust extract in patients with mild extrinsic asthma.
Topics: Adolescent; Adult; Allergens; Anti-Asthmatic Agents; Asthma; Bronchi; Bronchial Provocation Tests; B | 1996 |
Allergen bronchoprovocation of patients with mild allergic asthma after ozone exposure.
Topics: Administration, Inhalation; Adolescent; Adult; Allergens; Asthma; Bronchial Provocation Tests; Envir | 1996 |
Eicosanoids and lipocortin-1 in BAL fluid in asthma: effects of smoking and inhaled glucocorticoids.
Topics: 6-Ketoprostaglandin F1 alpha; Administration, Inhalation; Adult; Annexin A1; Anti-Inflammatory Agent | 1996 |
Lung mechanics during induced bronchoconstriction.
Topics: Adenosine Triphosphate; Adult; Airway Resistance; Asthma; Bronchoconstriction; Bronchoconstrictor Ag | 1996 |
Intravenous lidocaine and oral mexiletine block reflex bronchoconstriction in asthmatic subjects.
Topics: Adult; Anesthetics, Local; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Double-Blind Me | 1996 |
Effect of intravenous magnesium sulphate on airway calibre and airway reactivity to histamine in asthmatic subjects.
Topics: Adult; Asthma; Bronchi; Cross-Over Studies; Double-Blind Method; Female; Forced Expiratory Volume; H | 1996 |
Effect of regular terbutaline on the airway response to inhaled budesonide.
Topics: Adrenergic beta-Agonists; Adult; Aerosols; Asthma; Bronchial Provocation Tests; Bronchodilator Agent | 1996 |
Effect of a leukotriene B4 receptor antagonist, LY293111, on allergen induced responses in asthma.
Topics: Adult; Allergens; Asthma; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Cross-Over Stud | 1996 |
Effect of allergen challenge on airway responsiveness to histamine and sodium metabisulphite in mild asthma.
Topics: Adult; Allergens; Asthma; Bronchial Provocation Tests; Cross-Over Studies; Forced Expiratory Volume; | 1996 |
Effect of a bed covering system in children with asthma and house dust mite hypersensitivity.
Topics: Adolescent; Allergens; Animals; Antigens, Dermatophagoides; Asthma; Bedding and Linens; Blood Protei | 1997 |
Association of anxiety with perception of histamine induced bronchoconstriction in patients with asthma.
Topics: Adult; Anxiety; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Female; Forced Expiratory | 1997 |
Adenosine monophosphate and histamine induced bronchoconstriction: repeatability and protection by terbutaline.
Topics: Adenosine Monophosphate; Adult; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Bronchodil | 1997 |
Evaluation of efficacy of traditional Chinese medicines in the treatment of childhood bronchial asthma: clinical trial, immunological tests and animal study. Taiwan Asthma Study Group.
Topics: Adolescent; Animals; Asthma; Bronchi; Bronchoalveolar Lavage Fluid; Child; Dinoprostone; Double-Blin | 1996 |
Effects of experimental rhinovirus 16 infection on airway hyperresponsiveness to bradykinin in asthmatic subjects in vivo.
Topics: Adult; Asthma; Bradykinin; Bronchial Hyperreactivity; Bronchial Provocation Tests; Common Cold; Cons | 1997 |
Nitrogen dioxide exposure enhances asthmatic reaction to inhaled allergen in subjects with asthma.
Topics: Administration, Inhalation; Adolescent; Adult; Airway Resistance; Allergens; Asthma; Atmosphere Expo | 1997 |
Effect of experimental rhinovirus 16 colds on airway hyperresponsiveness to histamine and interleukin-8 in nasal lavage in asthmatic subjects in vivo.
Topics: Adolescent; Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Common Cold; Doub | 1997 |
The effect of inhaled leukotriene B4 in normal and in asthmatic subjects.
Topics: Administration, Inhalation; Adult; Airway Resistance; Asthma; Bronchial Provocation Tests; Cross-Ove | 1997 |
The effect of a novel orally active selective PDE4 isoenzyme inhibitor (CDP840) on allergen-induced responses in asthmatic subjects.
Topics: Adolescent; Adult; Allergens; Asthma; Bronchi; Bronchial Hyperreactivity; Bronchial Provocation Test | 1997 |
Studies of the effects of inhaled magnesium on airway reactivity to histamine and adenosine monophosphate in asthmatic subjects.
Topics: Adenosine Monophosphate; Administration, Inhalation; Adult; Asthma; Bronchial Hyperreactivity; Bronc | 1997 |
Allergen reduction measures in houses of allergic asthmatic patients: effects of air-cleaners and allergen-impermeable mattress covers.
Topics: Adolescent; Adult; Air Pollutants; Allergens; Animals; Asthma; Bedding and Linens; Bronchial Provoca | 1997 |
[The influence of heparin on histamine level in plasma during the early reaction phase of asthma].
Topics: Administration, Inhalation; Adult; Asthma; Bronchial Provocation Tests; Double-Blind Method; Forced | 1997 |
[Breath condensate as a method of noninvasive assessment of inflammation mediators from the lower airways].
Topics: Asthma; Biomarkers; Breath Tests; Bronchial Provocation Tests; Histamine; Humans; Leukotrienes; Resp | 1997 |
Effect of pretreatment with heparin on pulmonary and cutaneous response.
Topics: Administration, Inhalation; Adolescent; Adult; Aged; Asthma; Bronchial Provocation Tests; Bronchocon | 1997 |
[Pulmonary function tests and bronchial reactiveness with histamine in patients with atopic dermatitis and bronchial asthma].
Topics: Adolescent; Adult; Asthma; Bronchi; Dermatitis, Atopic; Female; Histamine; Humans; Immunoglobulin E; | 1996 |
Experimental rhinovirus 16 infection. Effects on cell differentials and soluble markers in sputum in asthmatic subjects.
Topics: Adolescent; Adult; Asthma; Biomarkers; Double-Blind Method; Female; Histamine; Humans; Male; Picorna | 1997 |
Experimental rhinovirus 16 infection. Effects on cell differentials and soluble markers in sputum in asthmatic subjects.
Topics: Adolescent; Adult; Asthma; Biomarkers; Double-Blind Method; Female; Histamine; Humans; Male; Picorna | 1997 |
Experimental rhinovirus 16 infection. Effects on cell differentials and soluble markers in sputum in asthmatic subjects.
Topics: Adolescent; Adult; Asthma; Biomarkers; Double-Blind Method; Female; Histamine; Humans; Male; Picorna | 1997 |
Experimental rhinovirus 16 infection. Effects on cell differentials and soluble markers in sputum in asthmatic subjects.
Topics: Adolescent; Adult; Asthma; Biomarkers; Double-Blind Method; Female; Histamine; Humans; Male; Picorna | 1997 |
Experimental rhinovirus 16 infection. Effects on cell differentials and soluble markers in sputum in asthmatic subjects.
Topics: Adolescent; Adult; Asthma; Biomarkers; Double-Blind Method; Female; Histamine; Humans; Male; Picorna | 1997 |
Experimental rhinovirus 16 infection. Effects on cell differentials and soluble markers in sputum in asthmatic subjects.
Topics: Adolescent; Adult; Asthma; Biomarkers; Double-Blind Method; Female; Histamine; Humans; Male; Picorna | 1997 |
Experimental rhinovirus 16 infection. Effects on cell differentials and soluble markers in sputum in asthmatic subjects.
Topics: Adolescent; Adult; Asthma; Biomarkers; Double-Blind Method; Female; Histamine; Humans; Male; Picorna | 1997 |
Experimental rhinovirus 16 infection. Effects on cell differentials and soluble markers in sputum in asthmatic subjects.
Topics: Adolescent; Adult; Asthma; Biomarkers; Double-Blind Method; Female; Histamine; Humans; Male; Picorna | 1997 |
Experimental rhinovirus 16 infection. Effects on cell differentials and soluble markers in sputum in asthmatic subjects.
Topics: Adolescent; Adult; Asthma; Biomarkers; Double-Blind Method; Female; Histamine; Humans; Male; Picorna | 1997 |
Increased allergen-specific Th2 responses in vitro in atopic subjects receiving subclinical allergen challenge.
Topics: Allergens; Asthma; Bronchial Provocation Tests; Double-Blind Method; Histamine; Humans; Immunoenzyme | 1997 |
[The influence of multiple histamine inhalation on nonspecific airway hyperresponsiveness to histamine in patients with bronchial asthma].
Topics: Administration, Inhalation; Adolescent; Adult; Aged; Asthma; Drug Administration Schedule; Female; H | 1997 |
Testing bronchial hyper-responsiveness: provocation or peak expiratory flow variability?
Topics: Adult; Aged; Algorithms; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Histamine; | 1997 |
Changes in neurokinin A (NKA) airway responsiveness with inhaled frusemide in asthma.
Topics: Administration, Inhalation; Adult; Analysis of Variance; Asthma; Bronchial Hyperreactivity; Bronchia | 1997 |
Study of clinical effects of immunotherapy in childhood asthma.
Topics: Adolescent; Allergens; Animals; Asthma; Bronchial Hyperreactivity; Child; Child, Preschool; Desensit | 1997 |
The influence of respiratory sounds on breathlessness in children with asthma: a symptom-perception approach.
Topics: Adolescent; Airway Obstruction; Asthma; Child; Exercise; Female; Histamine; Histamine Agents; Humans | 1997 |
[Comparison of the effect of two budesonide preparations for treatment of bronchial asthma in children].
Topics: Administration, Inhalation; Adolescent; Asthma; Bronchial Provocation Tests; Bronchodilator Agents; | 1997 |
Comparison of salmeterol and albuterol-induced bronchoprotection against adenosine monophosphate and histamine in mild asthma.
Topics: Adenosine Monophosphate; Adrenergic beta-Agonists; Adult; Albuterol; Asthma; Bronchial Provocation T | 1997 |
Effects of thoracoscopic upper dorsal sympathicolysis for essential hyperhidrosis on bronchial responsiveness to histamine: implications on the autonomic imbalance theory of asthma.
Topics: Adolescent; Adult; Analysis of Variance; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Te | 1996 |
Allergen-induced airway reactions in atopic asthmatics correlate with allergen-specific IL-5 response by BAL cells.
Topics: Adult; Allergens; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar La | 1997 |
Long-term effects of formoterol and salbutamol on bronchial hyperreactivity and beta-adrenoceptor density on lymphocytes in children with bronchial asthma.
Topics: Adrenergic beta-Agonists; Airway Resistance; Albuterol; Asthma; Bronchial Hyperreactivity; Bronchodi | 1996 |
Excessive bronchoconstriction induced by histamine and effects of volume history in patients with bronchial asthma.
Topics: Adult; Airway Resistance; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Female; Forced E | 1997 |
Respiratory muscle activity in the assessment of bronchial responsiveness in asthmatic children.
Topics: Administration, Inhalation; Adolescent; Asthma; Bronchi; Child; Diaphragm; Electromyography; Female; | 1998 |
Effect of angiotensin II on histamine-induced bronchoconstriction in the human airway both in vitro and in vivo.
Topics: Adult; Aged; Analysis of Variance; Angiotensin II; Asthma; Bronchi; Bronchial Provocation Tests; Bro | 1997 |
[The effect of nedocromil sodium on the clinical course, ventilatory parameters and nonspecific bronchial hyperreactivity in patients with nonatopic bronchial asthma treated with beclomethasone dipropionate].
Topics: Adult; Aged; Asthma; Beclomethasone; Bronchial Hyperreactivity; Double-Blind Method; Drug Administra | 1997 |
Effects of single-dose zileuton on bronchial hyperresponsiveness in asthmatic patients treated with inhaled corticosteroids.
Topics: Administration, Inhalation; Adrenal Cortex Hormones; Adult; Asthma; Bronchial Hyperreactivity; Bronc | 1997 |
Breathing pattern variability during bronchial histamine and methacholine challenges in asthmatics.
Topics: Administration, Inhalation; Adolescent; Adult; Airway Resistance; Analysis of Variance; Asthma; Bron | 1996 |
Hyperventilation during bronchial challenges in asthmatics: reproducibility and assessment of contributing factors.
Topics: Administration, Inhalation; Adolescent; Airway Resistance; Asthma; Bronchial Provocation Tests; Bron | 1996 |
Relationship between exhaled nitric oxide and airway hyperresponsiveness following experimental rhinovirus infection in asthmatic subjects.
Topics: Adult; Aerosols; Asthma; Bronchial Hyperreactivity; Female; Forced Expiratory Volume; Histamine; Hum | 1998 |
Benefits from adding the 5-lipoxygenase inhibitor zileuton to conventional therapy in aspirin-intolerant asthmatics.
Topics: Adrenergic beta-Agonists; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchial Hyperr | 1998 |
The airway effects of stopping regular oral theophylline in patients with asthma.
Topics: Administration, Oral; Adult; Asthma; Bronchoconstriction; Bronchodilator Agents; Cyclic AMP; Double- | 1998 |
Repeated exposure to an ambient level of NO2 enhances asthmatic response to a nonsymptomatic allergen dose.
Topics: Adult; Air Pollutants; Allergens; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Do | 1998 |
Effect of endogenous nitric oxide inhibition on airway responsiveness to histamine and adenosine-5'-monophosphate in asthma.
Topics: Adenosine Monophosphate; Administration, Inhalation; Adult; Asthma; Breath Tests; Bronchial Provocat | 1998 |
Effects of theophylline on tolerance to the bronchoprotective actions of salmeterol in asthmatics in vivo.
Topics: Administration, Inhalation; Adrenergic beta-Agonists; Adult; Albuterol; Asthma; Bronchi; Bronchial P | 1998 |
Lack of interaction of hyperpnoea with methacholine and histamine in asthma.
Topics: Adult; Asthma; Bronchial Provocation Tests; Bronchoconstrictor Agents; Cold Temperature; Dose-Respon | 1998 |
Effects of cysteinyl-leukotriene receptor antagonist, thromboxane A2 receptor antagonist, and thromboxane A2 synthetase inhibitor on antigen-induced bronchoconstriction in patients with asthma.
Topics: Administration, Oral; Adult; Anti-Asthmatic Agents; Antigens; Asthma; Benzoquinones; Blood Proteins; | 1998 |
Clearance in small ciliated airways in allergic asthmatics after bronchial allergen provocation.
Topics: Adult; Asthma; Bronchi; Bronchial Provocation Tests; Female; Histamine; Humans; Linear Models; Male; | 1999 |
Effect of inhaled steroids on airway hyperresponsiveness, sputum eosinophils, and exhaled nitric oxide levels in patients with asthma.
Topics: Administration, Inhalation; Adult; Androstadienes; Anti-Inflammatory Agents; Asthma; Biomarkers; Bre | 1999 |
Salbutamol pretreatment does not change eosinophil percentage and eosinophilic cationic protein concentration in hypertonic saline-induced sputum in asthmatic subjects.
Topics: Adrenergic beta-Agonists; Adult; Albuterol; Asthma; Blood Proteins; Bronchial Provocation Tests; Bro | 1999 |
Dynamics of eicosanoids in peripheral blood cells during bronchial provocation in aspirin-intolerant asthmatics.
Topics: Adult; Aspirin; Asthma; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Cells, Cultured; | 1999 |
The effect of processing on inflammatory markers in induced sputum.
Topics: Asthma; Basophils; Biomarkers; Blood Proteins; Bronchial Provocation Tests; Bronchoalveolar Lavage F | 1999 |
Aerosol recovery from large-volume reservoir delivery systems is highly dependent on the static properties of the reservoir.
Topics: Administration, Inhalation; Adult; Aerosols; Asthma; Bronchial Provocation Tests; Cross-Over Studies | 1999 |
Effects of swimming training on aerobic capacity and exercise induced bronchoconstriction in children with bronchial asthma.
Topics: Asthma; Bronchoconstriction; Child; Exercise Test; Exercise Therapy; Female; Forced Expiratory Volum | 1999 |
Differential effect of formoterol on adenosine monophosphate and histamine reactivity in asthma.
Topics: Adenosine Diphosphate; Adrenergic beta-Agonists; Adult; Albuterol; Asthma; Bronchi; Bronchial Provoc | 1999 |
Immunoglobulin E-independent major histocompatibility complex-restricted T cell peptide epitope-induced late asthmatic reactions.
Topics: Adult; Allergens; Amino Acid Sequence; Animals; Asthma; Basophils; Cats; Female; Glycoproteins; Hist | 1999 |
[Evaluation of efficacy and safety of intrabronchial specific immunotherapy with allergy medication against allergies to house mites among patients with bronchial asthma].
Topics: Adolescent; Adrenergic beta-Agonists; Adult; Allergens; Animals; Asthma; Bronchial Provocation Tests | 1999 |
[Comparison of exercise and histamine provocation tests in patients with bronchial asthma].
Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Bronchial Provocation Tests; Exercise Test; Fem | 1999 |
Treatment of late-onset asthma with fluconazole.
Topics: Adult; Aged; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Antifungal Agents; Asthma; Double-Blin | 1999 |
Effect of oral L-arginine on airway hyperresponsiveness to histamine in asthma.
Topics: Analysis of Variance; Arginine; Asthma; Bronchial Hyperreactivity; Cross-Over Studies; Double-Blind | 1999 |
[Bronchial hyperreactivity to histamine and levels of serum eosinophil cationic protein in patients with non-atopic asthma].
Topics: Adult; Asthma; Blood Proteins; Eosinophil Granule Proteins; Eosinophils; Female; Histamine; Humans; | 1999 |
Increased specific airway reactivity of persons with mild allergic asthma after 7.6 hours of exposure to 0.16 ppm ozone.
Topics: Adult; Allergens; Animals; Antigens, Dermatophagoides; Asthma; Bronchial Hyperreactivity; Female; Gl | 1999 |
Variability in lung deposition of inhaled drug, within and between asthmatic patients, with a pMDI and a dry powder inhaler, Turbuhaler.
Topics: Administration, Inhalation; Adult; Anti-Asthmatic Agents; Asthma; Bronchi; Bronchoconstrictor Agents | 2000 |
Perception of respiratory sensation assessed by means of histamine challenge and threshold loading tests.
Topics: Adolescent; Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstricti | 2000 |
Cetirizine inhibits bradykinin-induced cutaneous wheal and flare in atopic and healthy subjects.
Topics: Adolescent; Adult; Asthma; Bradykinin; Cetirizine; Cross-Over Studies; Dermatitis, Allergic Contact; | 2000 |
The current single exhalation method of measuring exhales nitric oxide is affected by airway calibre.
Topics: Adult; Asthma; Breath Tests; Cross-Sectional Studies; Cystic Fibrosis; Forced Expiratory Volume; His | 2000 |
Optimal asthma control, starting with high doses of inhaled budesonide.
Topics: Administration, Inhalation; Adult; Aged; Asthma; Bronchial Hyperreactivity; Bronchodilator Agents; B | 2000 |
Lidocaine inhalation for local anaesthesia and attenuation of bronchial hyper-reactivity with least airway irritation. Effect of three different dose regimens.
Topics: Adult; Airway Resistance; Anesthetics, Inhalation; Anesthetics, Local; Asthma; Bronchi; Bronchial Hy | 2000 |
Salbutamol via Easyhaler is at least as effective as salbutamol via Turbuhaler in the treatment of histamine-induced bronchoconstriction.
Topics: Administration, Inhalation; Adult; Albuterol; Asthma; Bronchial Hyperreactivity; Bronchial Provocati | 2000 |
[Evaluation of the relationship between the clinical course of severe asthma and ventilatory parameters].
Topics: Adult; Aged; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Female; Histamine; Huma | 2000 |
Pulmonary gas exchange responses to histamine and methacholine challenges in mild asthma.
Topics: Adult; Airway Resistance; Asthma; Blood Gas Analysis; Cross-Over Studies; Double-Blind Method; Femal | 2001 |
The role of n-6 polyunsaturated fat in stable asthmatics.
Topics: Asthma; Cross-Over Studies; Fatty Acids; Female; Forced Expiratory Volume; Histamine; Humans; Linole | 2001 |
Late asthmatic reactions provoked by intradermal injection of T-cell peptide epitopes are not associated with bronchial mucosal infiltration of eosinophils or T(H)2-type cells or with elevated concentrations of histamine or eicosanoids in bronchoalveolar
Topics: Adult; Allergens; Animals; Asthma; Bronchi; Bronchoalveolar Lavage Fluid; Cats; Eicosanoids; Eosinop | 2001 |
Is the increase in bronchial responsiveness or FEV1 shortly after cessation of beta2-agonists reflecting a real deterioration of the disease in allergic asthmatic patients? A comparison between short-acting and long-acting beta2-agonists.
Topics: Adrenergic beta-Agonists; Adult; Albuterol; Asthma; Bronchial Hyperreactivity; Double-Blind Method; | 2002 |
Alterations in airway inflammation and lung function during corticosteroid therapy for atopic asthma.
Topics: Administration, Inhalation; Administration, Topical; Adult; Androstadienes; Anti-Inflammatory Agents | 2002 |
[Sensitivity of the bronchopulmonary apparatus to the inhalation of biologically active substances in different forms of bronchial asthma].
Topics: Acetylcholine; Adolescent; Adrenergic beta-Agonists; Adult; Asthma; Bronchi; Chronic Disease; Clinic | 1978 |
[Drug prevention of bronchial asthma: inhibition of histamine and exercise-induced asthma by a new anti-anaphylactic oral preparation (ketotifen) (author's transl)].
Topics: Adult; Asthma; Bronchial Spasm; Clemastine; Cromolyn Sodium; Histamine; Histamine H1 Antagonists; Hu | 1978 |
Effects of H1- and H2-receptor blocking agents on histamine-induced bronchoconstriction in non-asthmatic subjects.
Topics: Administration, Oral; Adult; Airway Resistance; Asthma; Chlorpheniramine; Cimetidine; Forced Expirat | 1979 |
Selectivity of beta adrenoreceptor antagonist drugs assessed by histamine bronchial provocation.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Airway Resistance; Asthma; Double-Blind Method; Drug | 1979 |
The effects of H1 and H2 antihistamines on histamine inhalation challenges in asthmatic patients.
Topics: Adolescent; Adult; Airway Resistance; Asthma; Bronchial Provocation Tests; Chlorpheniramine; Cimetid | 1979 |
Menaquinone (vitamin K2) therapy for bronchial asthma. II. Clinical effect of menaquinone on bronchial asthma.
Topics: Asthma; Azathioprine; Clinical Trials as Topic; Desensitization, Immunologic; Drug Combinations; gam | 1975 |
Clinical investigation of agents with prophylactic anti-allergic effects in bronchial asthma.
Topics: Acetylcholine; Aerosols; Asthma; Clemastine; Clinical Trials as Topic; Cromolyn Sodium; Double-Blind | 1978 |
Effects of orally administered sodium cromoglycate in asthma and urticaria due to foods.
Topics: Administration, Oral; Adult; Asthma; Cromolyn Sodium; Female; Food Hypersensitivity; Histamine; Huma | 1978 |
Sodium cromoglycate-induced changes in the dose-response curve of inhaled methacholine and histamine in asthmatic children.
Topics: Adolescent; Asthma; Bronchi; Child; Clinical Trials as Topic; Cromolyn Sodium; Double-Blind Method; | 1979 |
Immunotherapy in cat-induced asthma. Double-blind trial with evaluation of bronchial responses to cat allergen and histamine.
Topics: Allergens; Animals; Asthma; Bronchi; Cats; Clinical Trials as Topic; Double-Blind Method; Hair; Hist | 1978 |
Inhaled antihistamines--bronchodilatation and effects on histamine- and methacholine-induced bronchoconstriction.
Topics: Adult; Aerosols; Asthma; Bronchi; Clemastine; Clinical Trials as Topic; Dose-Response Relationship, | 1978 |
Protective antiallergic effects of a new coumarin compound (BM 15.100) in experimental asthma.
Topics: Airway Resistance; Asthma; Coumarins; Forced Expiratory Volume; Histamine; Humans; Hypersensitivity; | 1979 |
Comparison of histamine bronchial challenges with the Wright nebulizer and the dosimeter.
Topics: Adolescent; Adult; Aerosols; Asthma; Bronchial Provocation Tests; Dose-Response Relationship, Drug; | 1979 |
The response of normal and asthmatic subjects to prostaglandins E2 and F2alpha by different routes, and their significance in asthma.
Topics: Adolescent; Adult; Aerosols; Allergens; Asthma; Bronchi; Clinical Trials as Topic; Dose-Response Rel | 1976 |
Biphasic reaction after inhalation of Haemophilus influenzae in patients with chronic nonspecific lung disease.
Topics: Adult; Antibodies, Bacterial; Asthma; Clinical Trials as Topic; Complement C3; Complement C4; Cromol | 1975 |
Bronchial reactivity to histamine before and after sodium cromoglycate in bronchial asthma.
Topics: Adolescent; Adult; Aerosols; Allergens; Asthma; Bronchi; Clinical Trials as Topic; Cromolyn Sodium; | 1976 |
Cromolyn therapy in patients with bronchial asthma. Effect on inhalation challenge with allergen, histamine, and methacholine.
Topics: Adolescent; Adult; Allergens; Asthma; Bronchi; Child; Clinical Trials as Topic; Cromolyn Sodium; Fem | 1976 |
Effect of acupuncture on bronchial asthma.
Topics: Acupuncture Therapy; Adolescent; Adult; Aged; Asthma; Blood Pressure; Carbon Dioxide; Female; Forced | 1976 |
[The effect of peat preparation on the release of histamine from basophils of atopic bronchial asthma].
Topics: Adult; Asthma; Basophils; Female; Histamine; Humans; Male | 1992 |
Relative amount of albuterol delivered to lung receptors from a metered-dose inhaler and nebulizer solution. Bioassay by histamine bronchoprovocation.
Topics: Adult; Albuterol; Asthma; Bronchial Provocation Tests; Dose-Response Relationship, Drug; Female; For | 1992 |
Effect of inhaled beclomethasone and nedocromil sodium on bronchial hyperresponsiveness to histamine and distilled water.
Topics: Administration, Inhalation; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Becl | 1992 |
Effect of indomethacin on leukotriene4-induced histamine hyperresponsiveness in asthmatic subjects.
Topics: Adult; Airway Resistance; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Female; Hi | 1992 |
Inhaled atrial natriuretic peptide and asthmatic airways.
Topics: Administration, Inhalation; Asthma; Atrial Natriuretic Factor; Double-Blind Method; Female; Forced E | 1992 |
[A study on the functional condition of airway muscarinic M2-receptors in asthma].
Topics: Adolescent; Adult; Airway Resistance; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Fema | 1992 |
Modification of bronchial reactivity by physiological concentrations of plasma epinephrine.
Topics: Adult; Asthma; Blood Pressure; Bronchi; Bronchoconstriction; Epinephrine; Forced Expiratory Volume; | 1992 |
Formoterol compared with beclomethasone and placebo on allergen-induced asthmatic responses.
Topics: Adult; Airway Resistance; Asthma; Beclomethasone; Blood Cell Count; Blood Proteins; Bronchial Provoc | 1992 |
Cough induced by ACE-inhibitors. A kinin related phenomenon?
Topics: Adult; Asthma; Bradykinin; Captopril; Cough; Double-Blind Method; Histamine; Humans; Hypertension | 1992 |
Airway responsiveness and cough induced by angiotensin converting enzyme inhibition.
Topics: Adult; Airway Resistance; Angiotensin-Converting Enzyme Inhibitors; Asthma; Bradykinin; Bronchi; Bro | 1992 |
The effects of an oral thromboxane TP receptor antagonist BAY u 3405, on prostaglandin D2- and histamine-induced bronchoconstriction in asthma, and relationship to plasma drug concentrations.
Topics: Adult; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Carbazoles; Female; Histamine; Hist | 1992 |
Modification of histamine- and methacholine-induced bronchoconstriction by calcium antagonist gallopamil in asthmatics.
Topics: Adult; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Dose-Response Relationship, Drug; D | 1992 |
Inflammatory response to acute inhalation of endotoxin in asthmatic patients.
Topics: Administration, Inhalation; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; C-Reacti | 1992 |
Low dose fenoterol aerosol protects against histamine-induced bronchoconstriction in mild asthmatics: a dose response study.
Topics: Adult; Aerosols; Asthma; Bronchial Hyperreactivity; Bronchoconstriction; Dosage Forms; Dose-Response | 1992 |
Changes in cross-sectional airway areas induced by methacholine, histamine, and LTC4 in asthmatic subjects.
Topics: Analysis of Variance; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Histamine; Humans; M | 1992 |
Effect of inhaled ipratropium bromide on the airway response to methacholine, histamine, and exercise in patients with mild bronchial asthma.
Topics: Adult; Aerosols; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Exercise; Female; Histami | 1992 |
The effect of inhaled gallopamil, a potent calcium channel blocker, on the late-phase response in subjects with allergic asthma.
Topics: Administration, Inhalation; Adolescent; Adult; Allergens; Asthma; Bronchial Provocation Tests; Drug | 1992 |
Allergen-induced increase in airway responsiveness is not inhibited by acute treatment with ketotifen or clemastine.
Topics: Adult; Airway Resistance; Allergens; Analysis of Variance; Asthma; Clemastine; Cromolyn Sodium; Dose | 1992 |
Effect of hyposensitization upon the immediate and late asthmatic reaction and upon histamine reactivity in patients allergic to house dust mite (Dermatophagoides pteronyssinus).
Topics: Administration, Inhalation; Adolescent; Adult; Animals; Asthma; Bronchi; Bronchial Provocation Tests | 1992 |
The relative contributions of histamine and prostanoids to bronchoconstriction provoked by isocapnic hyperventilation in asthma.
Topics: Adolescent; Adult; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Double-Blind Method; Fe | 1992 |
Single-dose effect of astemizole on bronchoconstriction induced by histamine in asthmatic subjects.
Topics: Adult; Aged; Astemizole; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Double-Blind Meth | 1992 |
Repeated inhalation of bradykinin attenuates adenosine 5'-monophosphate (AMP) induced bronchoconstriction in asthmatic airways.
Topics: Adenosine Monophosphate; Adult; Asthma; Bradykinin; Bronchial Provocation Tests; Bronchoconstriction | 1992 |
Effect of ibudilast: a novel antiasthmatic agent, on airway hypersensitivity in bronchial asthma.
Topics: Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Cromolyn Sodium; Female; Hist | 1992 |
The effect of disodium cromoglycate against bronchial hyperresponsiveness in asthmatic children.
Topics: Administration, Inhalation; Adolescent; Asthma; Bronchi; Bronchial Provocation Tests; Child; Cromoly | 1992 |
Leukotrienes C4, D4, and E4 enhance histamine responsiveness in asthmatic airways.
Topics: Airway Resistance; Asthma; Bronchial Provocation Tests; Dose-Response Relationship, Drug; Double-Bli | 1991 |
Effect of cetirizine on histamine- and leukotriene D4-induced bronchoconstriction in patients with atopic asthma.
Topics: Adult; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Cetirizine; Double-Blind Method; Dr | 1991 |
The effect of inhaled ipratropium bromide alone and in combination with oral terfenadine on bronchoconstriction provoked by adenosine 5'-monophosphate and histamine in asthma.
Topics: Adenosine Monophosphate; Administration, Inhalation; Administration, Oral; Adult; Asthma; Benzhydryl | 1991 |
The inhibitory effect of terfenadine and flurbiprofen on early and late-phase bronchoconstriction following allergen challenge in atopic asthma.
Topics: Adolescent; Adult; Allergens; Asthma; Benzhydryl Compounds; Bronchial Provocation Tests; Female; Flu | 1990 |
Is an abbreviated bronchial challenge with histamine valid?
Topics: Adult; Asthma; Bronchial Provocation Tests; Dose-Response Relationship, Drug; Female; Forced Expirat | 1992 |
The relationship between airway responsiveness measured before and after the allergen-induced late asthmatic response.
Topics: Airway Resistance; Allergens; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Female | 1992 |
Inhaled and oral salbutamol: how effective in the prophylaxis of asthma?
Topics: Administration, Inhalation; Administration, Oral; Adolescent; Adult; Albuterol; Animals; Antigens; A | 1991 |
Inhaled clemastine, an H1 antihistamine inhibits airway narrowing caused by aerosols of non-isotonic saline.
Topics: Administration, Inhalation; Adult; Aerosols; Asthma; Bronchial Hyperreactivity; Bronchial Provocatio | 1991 |
Effect of felodipine on histamine and adenosine induced bronchoconstriction in patients with asthma.
Topics: Adenosine Monophosphate; Adult; Asthma; Bronchoconstriction; Double-Blind Method; Felodipine; Histam | 1991 |
Effect of leukotriene antagonist on experimental and clinical bronchial asthma.
Topics: Allergens; Anaphylaxis; Animals; Asthma; Bronchi; Bronchial Provocation Tests; Chromones; Drug Evalu | 1991 |
Influence of elevated plasma levels of atrial natriuretic factor on bronchial reactivity in asthma.
Topics: Adult; Asthma; Atrial Natriuretic Factor; Blood Pressure; Bronchial Provocation Tests; Epinephrine; | 1991 |
The protective effect of a beta 2 agonist against excessive airway narrowing in response to bronchoconstrictor stimuli in asthma and chronic obstructive lung disease.
Topics: Adult; Aged; Airway Obstruction; Albuterol; Asthma; Bronchoconstriction; Dose-Response Relationship, | 1991 |
Action of budesonide on asthmatic bronchial hyperresponsiveness. Effects on directly and indirectly acting bronchoconstrictors.
Topics: Adolescent; Adult; Aerosols; Airway Resistance; Asthma; Bradykinin; Bronchoconstriction; Bronchodila | 1991 |
Transdermal delivery of the alpha 2-agonist clonidine does not alter airways responses to inhaled histamine or methacholine.
Topics: Administration, Cutaneous; Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Br | 1991 |
Terfenadine effect on the bronchoconstriction, dermal response, and leukopenia induced by platelet-activating factor.
Topics: Asthma; Bronchial Provocation Tests; Bronchoconstriction; Double-Blind Method; Histamine; Humans; Le | 1991 |
The inhibitory effect of nebulized albuterol on the early and late asthmatic reactions and increase in airway responsiveness provoked by inhaled allergen in asthma.
Topics: Administration, Inhalation; Adult; Albuterol; Allergens; Asthma; Bronchial Hyperreactivity; Bronchia | 1991 |
Effect of formoterol, a long-lasting beta 2-adrenoceptor agonist, against methacholine-induced bronchoconstriction.
Topics: Adrenergic beta-Agonists; Adult; Asthma; Blood Pressure; Bronchi; Double-Blind Method; Ethanolamines | 1990 |
Duration of the effect of astemizole on histamine-inhalation tests.
Topics: Administration, Inhalation; Adult; Aged; Astemizole; Asthma; Benzimidazoles; Bronchial Provocation T | 1990 |
Contribution of histamine and prostanoids to bronchoconstriction provoked by inhaled bradykinin in atopic asthma.
Topics: Adult; Asthma; Benzhydryl Compounds; Bradykinin; Bronchial Provocation Tests; Female; Flurbiprofen; | 1990 |
Effects of SK&F 104353, a leukotriene receptor antagonist, on the bronchial responses to histamine in subjects with asthma: a comparative study with terfenadine.
Topics: Adult; Asthma; Benzhydryl Compounds; Blood Pressure; Bronchi; Clinical Trials as Topic; Dicarboxylic | 1990 |
Dose-response relationship of the H1-histamine antagonist, ebastine, against histamine and methacholine-induced bronchoconstriction in patients with asthma.
Topics: Adult; Asthma; Bronchi; Butyrophenones; Dose-Response Relationship, Drug; Female; Forced Expiratory | 1990 |
Protection against allergen-induced asthma by salmeterol.
Topics: Administration, Inhalation; Adrenergic beta-Agonists; Adult; Albuterol; Analysis of Variance; Asthma | 1990 |
Inhaled beta-stimulants--a study of high-dose v. conventional-dose treatment in asthmatic outpatients.
Topics: Administration, Inhalation; Adolescent; Adult; Aged; Albuterol; Asthma; Bronchial Provocation Tests; | 1991 |
Effect of inhaled furosemide and bumetanide on adenosine 5'-monophosphate- and sodium metabisulfite-induced bronchoconstriction in asthmatic subjects.
Topics: Adenosine Monophosphate; Administration, Inhalation; Adult; Asthma; Bronchial Provocation Tests; Bro | 1991 |
Comparison of a beta 2-agonist, terbutaline, with an inhaled corticosteroid, budesonide, in newly detected asthma.
Topics: Adolescent; Adult; Asthma; Bronchial Provocation Tests; Bronchodilator Agents; Budesonide; Female; G | 1991 |
The distribution of bronchial responsiveness to histamine and exercise in 527 children and adolescents.
Topics: Adolescent; Asthma; Bronchi; Bronchial Provocation Tests; Child; Dose-Response Relationship, Drug; E | 1991 |
Airways responses to ipratropium bromide do not vary with time in asthmatic subjects. Studies of interindividual and intraindividual variation of bronchodilatation and protection against histamine-induced bronchoconstriction.
Topics: Administration, Inhalation; Adult; Asthma; Atropine Derivatives; Bronchi; Bronchial Provocation Test | 1990 |
Comparison of the effect of loratadine on the airway and skin responses to histamine, methacholine, and allergen in subjects with asthma.
Topics: Adult; Allergens; Asthma; Bronchi; Bronchial Provocation Tests; Cyproheptadine; Female; Histamine; H | 1990 |
Effect of sodium-transport inhibitors on bronchial reactivity in vivo.
Topics: Adolescent; Adult; Aged; Amiloride; Asthma; Bronchi; Digoxin; Dose-Response Relationship, Drug; Doub | 1990 |
Changes in airway resistance following nasal provocation.
Topics: Adult; Airway Resistance; Asthma; Bronchi; Double-Blind Method; Female; Histamine; Humans; Male; Met | 1990 |
Comparative protective effect of the inhaled beta 2-agonist salbutamol (albuterol) on bronchoconstriction provoked by histamine, methacholine, and adenosine 5'-monophosphate in asthma.
Topics: Adenosine Monophosphate; Administration, Inhalation; Adolescent; Adult; Aerosols; Albuterol; Asthma; | 1990 |
Effect of caffeine on histamine bronchoprovocation in asthma.
Topics: Asthma; Bronchi; Bronchial Provocation Tests; Caffeine; Double-Blind Method; Female; Forced Expirato | 1990 |
Repeated exposure of asthmatic airways to inhaled adenosine 5'-monophosphate attenuates bronchoconstriction provoked by exercise.
Topics: Adenosine; Adenosine Monophosphate; Administration, Inhalation; Adolescent; Adult; Asthma; Asthma, E | 1990 |
Lack of airway response to nasal irritation in normal and asthmatic subjects.
Topics: Adolescent; Adult; Airway Resistance; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Doub | 1990 |
Nitrendipine therapy in asthmatic subjects.
Topics: Adult; Asthma; Double-Blind Method; Female; Histamine; Humans; Hypertension; Male; Maximal Expirator | 1990 |
Dose-related effect of beclomethasone dipropionate on airway responsiveness in asthma.
Topics: Adult; Airway Resistance; Asthma; Beclomethasone; Dose-Response Relationship, Drug; Female; Forced E | 1990 |
Comparison of the effects of inhaled corticosteroids on the airway response to histamine, methacholine, hyperventilation, and sulfur dioxide in subjects with asthma.
Topics: Administration, Inhalation; Adrenal Cortex Hormones; Airway Resistance; Albuterol; Asthma; Beclometh | 1990 |
The effect of two months of treatment with inhaled budesonide on bronchial responsiveness to histamine and house-dust mite antigen in asthmatic children.
Topics: Administration, Inhalation; Administration, Topical; Adolescent; Animals; Anti-Inflammatory Agents; | 1990 |
Effect of nedocromil on bronchospasm induced by inhalation of substance P in asthmatic subjects.
Topics: Adolescent; Adult; Aerosols; Airway Resistance; Asthma; Bronchial Provocation Tests; Dose-Response R | 1988 |
Role of histamine release in hypertonic saline induced bronchoconstriction.
Topics: Adult; Asthma; Benzhydryl Compounds; Bronchi; Dose-Response Relationship, Drug; Female; Forced Expir | 1989 |
Effect of indomethacin on allergen-induced asthmatic responses.
Topics: Adult; Allergens; Asthma; Clinical Trials as Topic; Cyclooxygenase Inhibitors; Double-Blind Method; | 1989 |
Inhaled lysine-aspirin as a bronchoprovocation procedure in aspirin-sensitive asthma: its repeatability, absence of a late-phase reaction, and the role of histamine.
Topics: Aerosols; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchial Provocation Tests; Cli | 1989 |
The effect of oral prostaglandin E1 on airway responsiveness in asthmatic subjects.
Topics: Administration, Oral; Adult; Alprostadil; Asthma; Double-Blind Method; Forced Expiratory Volume; His | 1989 |
Ipratropium bromide (Atrovent) in childhood asthma: a cumulative dose-response study.
Topics: Adolescent; Asthma; Atropine Derivatives; Bronchi; Child; Dose-Response Relationship, Drug; Female; | 1989 |
Is there loss of protective muscarinic receptor mechanism in asthma?
Topics: Adult; Asthma; Bronchial Provocation Tests; Dose-Response Relationship, Drug; Drug Interactions; Fem | 1989 |
Long-term effect of ipratropium bromide and fenoterol on the bronchial hyperresponsiveness to histamine in children with asthma.
Topics: Adolescent; Asthma; Atropine Derivatives; Bronchi; Child; Dose-Response Relationship, Drug; Fenotero | 1989 |
Effect of a non-sedative antihistaminic (loratadine) in moderate asthma. A double-blind controlled clinical crossover-trial.
Topics: Adult; Asthma; Bronchi; Clinical Trials as Topic; Cyproheptadine; Double-Blind Method; Female; Force | 1989 |
The effects of dietary supplementation with fish oil lipids on the airways response to inhaled allergen in bronchial asthma.
Topics: Adolescent; Adult; Airway Resistance; Allergens; Asthma; Bronchi; Bronchial Provocation Tests; Chemo | 1989 |
The effect of oral terfenadine alone and in combination with flurbiprofen on the bronchoconstrictor response to inhaled adenosine 5'-monophosphate in nonatopic asthma.
Topics: Adenosine Monophosphate; Administration, Inhalation; Administration, Oral; Asthma; Benzhydryl Compou | 1989 |
The reducing effects of tazifylline on histamine-induced bronchoconstriction in atopic asthmatics.
Topics: Adolescent; Adult; Asthma; Bronchodilator Agents; Histamine; Histamine H1 Antagonists; Humans; Male; | 1989 |
Inhibition of hypertonic saline-induced bronchoconstriction by terfenadine and flurbiprofen. Evidence for the predominant role of histamine.
Topics: Adult; Asthma; Benzhydryl Compounds; Bronchi; Bronchial Provocation Tests; Dose-Response Relationshi | 1989 |
The inhibitory actions of azelastine hydrochloride on the early and late bronchoconstrictor responses to inhaled allergen in atopic asthma.
Topics: Adult; Allergens; Asthma; Bronchi; Female; Forced Expiratory Volume; Histamine; Histamine H1 Antagon | 1989 |
Effect of vasopressin on bronchial reactivity to histamine.
Topics: Adolescent; Adult; Arginine Vasopressin; Asthma; Bronchi; Bronchial Provocation Tests; Double-Blind | 1989 |
The inhibitory effect of azelastine hydrochloride on histamine- and allergen-induced bronchoconstriction in atopic asthma.
Topics: Administration, Inhalation; Administration, Oral; Adult; Asthma; Bronchi; Double-Blind Method; Force | 1989 |
Comparison of real and placebo acupuncture in histamine-induced asthma. A double-blind crossover study.
Topics: Acupuncture Therapy; Adult; Asthma; Bronchial Provocation Tests; Double-Blind Method; Female; Histam | 1989 |
Inhalation of hypertonic saline as a bronchial challenge in children with mild asthma and normal children.
Topics: Adolescent; Air; Asthma; Bronchial Provocation Tests; Child; Female; Forced Expiratory Volume; Hista | 1989 |
Lidocaine-induced bronchoconstriction in asthmatic patients. Relation to histamine airway responsiveness and effect of preservative.
Topics: Administration, Inhalation; Adult; Anesthesia, Local; Asthma; Bronchi; Bronchial Provocation Tests; | 1989 |
Hyposensitization in asthmatics with mPEG modified and unmodified house dust mite extract. II. Effect evaluated by challenges with allergen and histamine.
Topics: Animals; Asthma; Bronchial Provocation Tests; Desensitization, Immunologic; Histamine; Humans; Hyper | 1989 |
The effects of inhaled leukotriene E4 on the airway responsiveness to histamine in subjects with asthma and normal subjects.
Topics: Adult; Aerosols; Airway Resistance; Asthma; Bronchial Provocation Tests; Drug Synergism; Female; His | 1988 |
The effect of inhaled hexamethonium bromide and atropine sulphate on airway responsiveness to histamine.
Topics: Adult; Asthma; Atropine; Blood Pressure; Drug Interactions; Female; Forced Expiratory Volume; Heart | 1985 |
Beta-adrenoceptor blockade with propranolol and bronchial responsiveness to a number of bronchial provocation tests in non-asthmatic subjects.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Asthma; Bronchial Provocation Tests; Choline; Drug I | 1985 |
Circulating histamine and neutrophil chemotactic activity during allergen-induced asthma: the effect of inhaled antihistamines and anti-allergic compounds.
Topics: Adult; Allergens; Asthma; Bronchial Provocation Tests; Chemotaxis, Leukocyte; Clemastine; Cromolyn S | 1985 |
Terfenadine (Seldane) is a potent and selective histamine H1 receptor antagonist in asthmatic airways.
Topics: Adult; Asthma; Benzhydryl Compounds; Bronchi; Bronchial Provocation Tests; Clinical Trials as Topic; | 1987 |
The inhibitory effect of azelastine and ketotifen on histamine-induced bronchoconstriction in asthmatic patients.
Topics: Adult; Asthma; Bronchial Provocation Tests; Double-Blind Method; Female; Histamine; Histamine H1 Ant | 1987 |
Effect of cetirizine, a new histamine H1 antagonist, on airway dynamics and responsiveness to inhaled histamine in mild asthma.
Topics: Administration, Inhalation; Adult; Asthma; Bronchi; Bronchial Spasm; Cetirizine; Dose-Response Relat | 1987 |
Cetirizine inhibition of histamine-induced bronchospasm.
Topics: Adult; Analysis of Variance; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Bronchodilator Ag | 1987 |
Effects of a cyclo-oxygenase inhibitor, flurbiprofen, and an H1 histamine receptor antagonist, terfenadine, alone and in combination on allergen induced immediate bronchoconstriction in man.
Topics: Adult; Allergens; Asthma; Benzhydryl Compounds; Bronchi; Bronchial Provocation Tests; Drug Combinati | 1987 |
Rebound increase in bronchial responsiveness after treatment with inhaled terbutaline.
Topics: Adolescent; Adult; Asthma; Bronchi; Bronchial Provocation Tests; Clinical Trials as Topic; Double-Bl | 1988 |
Effect of azelastine on bronchoconstriction induced by histamine and leukotriene C4 in patients with extrinsic asthma.
Topics: Adult; Asthma; Clinical Trials as Topic; Double-Blind Method; Female; Forced Expiratory Volume; Hist | 1988 |
Comparative effects of rilmenidine and clonidine on bronchial responses to histamine in asthmatic subjects.
Topics: Adrenergic alpha-Agonists; Adult; Asthma; Bronchi; Clonidine; Female; Forced Expiratory Volume; Hist | 1988 |
Can mild bronchospasm reduce gastroesophageal reflux?
Topics: Aged; Asthma; Bronchial Provocation Tests; Esophagogastric Junction; Female; Forced Expiratory Volum | 1989 |
Lung mucociliary transport in asymptomatic asthma: effects of inhaled histamine.
Topics: Administration, Inhalation; Adult; Asthma; Female; Histamine; Humans; Lung; Male; Mucociliary Cleara | 1989 |
Increased bronchial responsiveness to histamine associated with shortened inhalation time.
Topics: Adolescent; Asthma; Bronchial Provocation Tests; Child; Histamine; Humans; Nebulizers and Vaporizers | 1989 |
Influence of albuterol, cromolyn sodium and ipratropium bromide on the airway and circulating mediator responses to allergen bronchial provocation in asthma.
Topics: Adult; Albuterol; Asthma; Atropine Derivatives; Bronchial Provocation Tests; Chemotactic Factors; Cr | 1985 |
[Vagal component in bronchial constriction induced by histamine: effect of ipratropium bromide].
Topics: Adult; Aged; Asthma; Atropine Derivatives; Bronchial Provocation Tests; Clinical Trials as Topic; Do | 1985 |
Histamine-induced bronchial response after administration of placebo, salbutamol and a combination of a beta-2-adrenergic drug (fenoterol) with an anticholinergic agent (ipratropium bromide) in asymptomatic asthma patients.
Topics: Adolescent; Adult; Albuterol; Asthma; Atropine Derivatives; Bronchial Provocation Tests; Bronchial S | 1986 |
Role of chemical mediators after antigen and exercise challenge in children with asthma.
Topics: Adolescent; Animals; Asthma; Bronchial Provocation Tests; Chemotactic Factors; Child; Cromolyn Sodiu | 1988 |
Mechanisms of bronchial hyperreactivity in cystic fibrosis.
Topics: Adolescent; Asthma; Bronchial Provocation Tests; Child; Cystic Fibrosis; Double-Blind Method; Fenote | 1988 |
Effect of parenteral magnesium on pulmonary function, plasma cAMP, and histamine in bronchial asthma.
Topics: Adolescent; Adult; Asthma; Child; Clinical Trials as Topic; Cyclic AMP; Double-Blind Method; Epineph | 1985 |
Effect of nedocromil sodium on histamine airway responsiveness in grass-pollen sensitive asthmatics during the pollen season.
Topics: Adult; Aerosols; Airway Resistance; Asthma; Bronchial Provocation Tests; Double-Blind Method; Female | 1986 |
The effect of an angiotensin converting enzyme inhibitor, ramipril, on bronchial responses to inhaled histamine and bradykinin in asthmatic subjects.
Topics: Adult; Asthma; Bradykinin; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Bronchial Provocation | 1987 |
The effect of nifedipine on bronchial reactivity to inhaled histamine and methacholine: a comparative study in normal and asthmatic subjects.
Topics: Adult; Airway Resistance; Asthma; Bronchial Provocation Tests; Female; Forced Expiratory Volume; His | 1988 |
The effect of trifluoperazine on bronchial responsiveness in asthma.
Topics: Adolescent; Adult; Asthma; Bronchi; Double-Blind Method; Forced Expiratory Volume; Histamine; Humans | 1988 |
A controlled study on the effect of treatment with cromolyn sodium pressurized aerosol on bronchial reactivity in patients with asthma.
Topics: Adolescent; Adult; Aerosols; Asthma; Bronchi; Child; Child, Preschool; Climate; Clinical Trials as T | 1986 |
Comparative effects of inhaled salbutamol, sodium cromoglycate, and beclomethasone dipropionate on allergen-induced early asthmatic responses, late asthmatic responses, and increased bronchial responsiveness to histamine.
Topics: Administration, Inhalation; Adolescent; Adult; Albuterol; Allergens; Asthma; Beclomethasone; Bronchi | 1987 |
Increased responsiveness to histamine after propranolol in subjects with asthma nonresponsive to the bronchoconstrictive effect of propranolol.
Topics: Adult; Airway Resistance; Asthma; Blood Pressure; Bronchi; Bronchial Provocation Tests; Drug Synergi | 1988 |
Increases in airway responsiveness to histamine precede allergen-induced late asthmatic responses.
Topics: Adult; Allergens; Asthma; Bronchial Provocation Tests; Dose-Response Relationship, Drug; Female; For | 1988 |
A new role for histamine H2-receptors in asthmatic airways.
Topics: Asthma; Bronchial Provocation Tests; Cimetidine; Forced Expiratory Volume; Histamine; Humans; Recept | 1988 |
The effect of inhaled ouabain on bronchial reactivity to histamine in man.
Topics: Administration, Inhalation; Adolescent; Adult; Asthma; Bronchi; Double-Blind Method; Forced Expirato | 1988 |
Use of bronchial provocation with histamine to compare the pharmacodynamics of inhaled albuterol and metaproterenol in patients with asthma.
Topics: Adolescent; Adult; Albuterol; Asthma; Bronchial Provocation Tests; Clinical Trials as Topic; Dose-Re | 1987 |
The effect of oral zindotrine (MDL-257), a bronchial smooth muscle relaxant, on histamine airways responsiveness in asymptomatic asthmatics.
Topics: Administration, Oral; Adult; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Bronchodilator Ag | 1987 |
A comparison of histamine and methacholine bronchial challenges using the DeVilbiss 646 nebulizer and the Rosenthal-French dosimeter.
Topics: Adult; Asthma; Bronchial Provocation Tests; Clinical Trials as Topic; Female; Forced Expiratory Volu | 1987 |
Effects of clonidine on bronchial responses to histamine in normal and asthmatic subjects.
Topics: Asthma; Bronchi; Bronchial Provocation Tests; Bronchial Spasm; Clonidine; Dose-Response Relationship | 1988 |
Relationship of serum theophylline concentrations to histamine-induced bronchospasm.
Topics: Administration, Inhalation; Adolescent; Adult; Asthma; Bronchial Spasm; Double-Blind Method; Female; | 1987 |
Reproducibility of early asthmatic response to Cladosporium herbarum.
Topics: Adult; Allergens; Asthma; Bronchial Provocation Tests; Cladosporium; Double-Blind Method; Forced Exp | 1986 |
Reproducibility of the late asthmatic response.
Topics: Adult; Allergens; Asthma; Bronchial Provocation Tests; Cladosporium; Double-Blind Method; Histamine; | 1986 |
A double-blind, multicenter immunotherapy trial in children, using a purified and standardized Cladosporium herbarum preparation. I. Clinical results.
Topics: Adolescent; Asthma; Bronchial Provocation Tests; Child; Child, Preschool; Cladosporium; Clinical Tri | 1986 |
Effects of the calcium channel blocker, verapamil, on asthmatic airway responses to muscarinic, histaminergic, and allergenic stimuli.
Topics: Adult; Allergens; Asthma; Calcium Channel Blockers; Forced Expiratory Volume; Histamine; Humans; Lun | 1986 |
Protective effect of theophylline on histamine-induced bronchoconstriction in asthmatic children.
Topics: Adolescent; Asthma; Bronchi; Child; Child, Preschool; Clinical Trials as Topic; Histamine; Humans; P | 1986 |
The combined effects of two pairs of mediators, adenosine with methacholine and prostaglandin D2 with histamine, on airway calibre in asthma.
Topics: Adenosine; Adult; Airway Resistance; Asthma; Bronchi; Dose-Response Relationship, Drug; Drug Synergi | 1986 |
The effect of bucindolol on the airway function of asthmatics.
Topics: Adult; Asthma; Bronchodilator Agents; Clinical Trials as Topic; Double-Blind Method; Female; Forced | 1986 |
A comparison of the refractory periods induced by hypertonic airway challenge and exercise in bronchial asthma.
Topics: Adult; Aerosols; Asthma; Bronchial Provocation Tests; Female; Forced Expiratory Volume; Histamine; H | 1987 |
Inhibitory effects of clonidine on the allergen-induced wheal-and-flare reactions in patients with extrinsic asthma.
Topics: Allergens; Asthma; Clonidine; Histamine; Humans; Hydrocortisone; Hypersensitivity, Delayed; Hypersen | 1987 |
Reduction of histamine-induced bronchoconstriction by magnesium in asthmatic subjects.
Topics: Administration, Inhalation; Adult; Asthma; Bronchial Provocation Tests; Female; Histamine; Humans; M | 1987 |
The contribution of histamine to immediate bronchoconstriction provoked by inhaled allergen and adenosine 5' monophosphate in atopic asthma.
Topics: Adenosine Monophosphate; Administration, Inhalation; Allergens; Asthma; Bronchial Spasm; Forced Expi | 1987 |
Pulmonary response to nasal-challenge testing of atopic subjects with stable asthma.
Topics: Adult; Airway Resistance; Allergens; Asthma; Forced Expiratory Volume; Functional Residual Capacity; | 1986 |
No influence of circulating noradrenaline on bronchial reactivity to histamine in asthmatic patients.
Topics: Adult; Airway Resistance; Asthma; Bronchi; Bronchial Provocation Tests; Female; Heart Rate; Histamin | 1986 |
Lack of acute effects of ascorbic acid on spirometry and airway responsiveness to histamine in subjects with asthma.
Topics: Adult; Airway Resistance; Ascorbic Acid; Asthma; Double-Blind Method; Female; Forced Expiratory Volu | 1986 |
Effect of nifedipine on dose-response curves to acetylcholine and histamine measured during quiet breathing.
Topics: Acetylcholine; Adult; Aged; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Dose-Response Rela | 1986 |
Effect of diltiazem on histamine- and carbachol-induced bronchospasm in normal and asthmatic subjects.
Topics: Adult; Asthma; Benzazepines; Bronchial Spasm; Calcium; Carbachol; Clinical Trials as Topic; Diltiaze | 1985 |
Effect of beclomethasone dipropionate on bronchial responsiveness to histamine in controlled nonsteroid-dependent asthma.
Topics: Adult; Analysis of Variance; Asthma; Beclomethasone; Bronchi; Clinical Trials as Topic; Female; Forc | 1985 |
[Effect of corinfar on histamine- or acetylcholine-induced bronchial spasm].
Topics: Acetylcholine; Adolescent; Asthma; Bronchi; Bronchial Provocation Tests; Bronchial Spasm; Child; Chi | 1985 |
Acute effect of ketotifen on the dose-response curve of histamine and methacholine in asthma.
Topics: Adolescent; Adult; Aged; Asthma; Bronchi; Bronchial Provocation Tests; Dose-Response Relationship, D | 1985 |
Protective effect by UCB JO28 against histamine and methacholine induced bronchial hyperreactivity.
Topics: Adolescent; Adult; Asthma; Bronchial Spasm; Clinical Trials as Topic; Female; Histamine; Humans; Mal | 1985 |
Failure of sulfites to produce clinical responses in patients with systemic mastocytosis or recurrent anaphylaxis: results of a single-blind study.
Topics: Administration, Oral; Adult; Anaphylaxis; Asthma; Clinical Trials as Topic; Female; Histamine; Human | 1985 |
Bronchial hyperreactivity after treatment with sodium cromoglycate in atopic asthmatic patients not exposed to relevant allergens.
Topics: Adult; Allergens; Asthma; Bronchi; Bronchial Diseases; Cromolyn Sodium; Female; Forced Expiratory Vo | 1985 |
Modification of bronchial hyperreactivity after treatment with sodium cromoglycate during pollen season.
Topics: Adolescent; Adult; Asthma; Bronchi; Bronchial Provocation Tests; Cromolyn Sodium; Female; Forced Exp | 1985 |
Bronchial hyperreactivity to leucotriene D4 and histamine in exogenous asthma.
Topics: Adolescent; Adult; Airway Resistance; Asthma; Bronchi; Clinical Trials as Topic; Dose-Response Relat | 1985 |
Long-term modification on histamine-induced bronchoconstriction by disodium cromoglycate and ketotifen versus placebo.
Topics: Adolescent; Adult; Asthma; Bronchi; Cromolyn Sodium; Female; Forced Expiratory Volume; Histamine; Hu | 1985 |
Immunotherapy with partially purified and standardized animal dander extracts. I. Clinical results from a double-blind study on patients with animal dander asthma.
Topics: Adolescent; Adult; Allergens; Animals; Asthma; Cats; Child, Preschool; Dogs; Female; Hair; Histamine | 1986 |
Theophylline partially inhibits bronchoconstriction caused by inhaled histamine in subjects with asthma.
Topics: Adult; Aged; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Female; Forced Expiratory Volume; | 1986 |
Specific antagonism of adenosine-induced bronchoconstriction in asthma by oral theophylline.
Topics: Adenosine; Adult; Airway Resistance; Asthma; Bronchi; Bronchodilator Agents; Female; Forced Expirato | 1985 |
Gastro-oesophageal reflux and childhood asthma: the acid test.
Topics: Adolescent; Asthma; Bronchial Provocation Tests; Child; Female; Gastroesophageal Reflux; Histamine; | 1985 |
Changes in bronchial hyperreactivity induced by 4 weeks of treatment with antiasthmatic drugs in patients with allergic asthma: a comparison between budesonide and terbutaline.
Topics: Adolescent; Adult; Asthma; Bronchial Provocation Tests; Budesonide; Double-Blind Method; Eosinophils | 1985 |
The effect of inhaled nifedipine on bronchial reactivity to histamine in man.
Topics: Adult; Aerosols; Asthma; Blood Pressure; Bronchi; Bronchial Provocation Tests; Bronchial Spasm; Fema | 1985 |
[Results in the therapy of bronchial asthma using histaglobine].
Topics: Adolescent; Adult; Asthma; Child; Clinical Trials as Topic; Drug Combinations; Female; Fever; gamma- | 1972 |
A new pair of hands.
Topics: Animals; Asthma; Clinical Trials as Topic; Histamine; Humans; Pentazocine; Rats | 1968 |
[Clinical controlled experimentation on a preparation of human gamma globulins, histamine and serotonin with antiallergic activity].
Topics: Adolescent; Adult; Asthma; Child; Clinical Trials as Topic; Drug Synergism; Female; gamma-Globulins; | 1968 |
[Histaglobin treatment of bronchial asthma in children].
Topics: Adolescent; Asthma; Bronchitis; Child; Child, Preschool; gamma-Globulins; Histamine; Humans; Infant; | 1970 |
The urinary excretion of 1-methylimidazole-4-acetic acid, a histamine metabolite, by healthy and asthmatic children.
Topics: Acetates; Acute Disease; Adolescent; Adrenocorticotropic Hormone; Adult; Asthma; Child; Child, Presc | 1973 |
Effect of alpha-receptor blocking drugs and disodium cromoglyate on histamine hypersensitivity in bronchial asthma.
Topics: Adolescent; Adrenergic alpha-Antagonists; Adult; Asthma; Bronchi; Calcium; Cell Membrane; Chromones; | 1970 |
Response of asthmatic airways to intravenous bradykinin and histamine.
Topics: Adolescent; Adult; Airway Obstruction; Asthma; Bradykinin; Female; Histamine; Humans; Injections, In | 1974 |
The use of histamine induced bronchoconstriction as a method for investigating bronchodilator drugs.
Topics: Acetylcholine; Airway Resistance; Asthma; Bronchi; Bronchodilator Agents; Catechols; Clinical Trials | 1972 |
Action of disodium cromoglycate.
Topics: Asthma; Child; Chromones; Clinical Trials as Topic; Cromolyn Sodium; Histamine; Humans; Placebos; Sp | 1972 |
Bronchial hyperreactivity to prostaglandin F 2 and histamine in patients with asthma.
Topics: Adult; Aerosols; Airway Resistance; Asthma; Bronchi; Constriction; Drug Hypersensitivity; Female; Hi | 1973 |
[On histaminopexy of the blood serum in patients with pulmonary tuberculosis and bronchial asthma].
Topics: Adolescent; Adult; Aged; Asthma; Blood Proteins; Clinical Trials as Topic; Female; Histamine; Humans | 1968 |
Comparative studies of the protective effect of Alupent and Th 1165a against histamine in man.
Topics: Aerosols; Analysis of Variance; Asthma; Blood Pressure; Bronchial Spasm; Bronchodilator Agents; Clin | 1971 |
1630 other studies available for histamine and Asthma, Bronchial
Article | Year |
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α-Asarone alleviates allergic asthma by stabilizing mast cells through inhibition of ERK/JAK2-STAT3 pathway.
Topics: Asthma; Cytokines; Histamine; Humans; Janus Kinase 2; MAP Kinase Signaling System; Mast Cells; STAT3 | 2023 |
Orally administered solasodine, a steroidal glycoalkaloid, suppresses ovalbumin-induced exaggerated Th2-immune response in rat model of bronchial asthma.
Topics: Allergens; Aluminum Hydroxide; Animals; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Dexamethaso | 2022 |
Endogenous Adenosine 5'-Monophosphate, But Not Acetylcholine or Histamine, is Associated with Asthma Control, Quality of Life, and Exacerbations.
Topics: Acetylcholine; Adenosine; Adenosine Monophosphate; Asthma; Biomarkers; Chemokine CCL22; Histamine; H | 2022 |
GSDM gene polymorphisms regulate the IgE level in asthmatic patients.
Topics: Adult; Asthma; Case-Control Studies; Child; Genetic Predisposition to Disease; Genotype; Histamine; | 2022 |
Topics: Alum Compounds; Animals; Asthma; Bronchoalveolar Lavage Fluid; Canavalia; Cytokines; Dexamethasone; | 2022 |
Histamine-releasing factor in severe asthma and rhinovirus-associated asthma exacerbation.
Topics: Animals; Asthma; Enterovirus Infections; Histamine; Humans; Immunoglobulin E; Immunoglobulin G; Mice | 2023 |
The Use of DAO as a Marker for Histamine Intolerance: Measurements and Determinants in a Large Random Population-Based Survey.
Topics: Adult; Amine Oxidase (Copper-Containing); Asthma; Female; Food; Food Hypersensitivity; Histamine; Hu | 2023 |
Recovery after histamine challenge test: effect of gender and body mass index.
Topics: Asthma; Body Mass Index; Bronchial Hyperreactivity; Bronchial Provocation Tests; Histamine; Humans; | 2023 |
Amitriptyline inhibits bronchoconstriction and directly promotes dilatation of the airways.
Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Albuterol; Amitriptyline; Animals; Asthma; Bronchoconstr | 2023 |
Rhinovirus C15 Induces Airway Hyperresponsiveness via Calcium Mobilization in Airway Smooth Muscle.
Topics: Asthma; Calcium Signaling; Carbachol; Cells, Cultured; Chemokine CXCL10; Enterovirus; Enterovirus In | 2020 |
[Effect of moxibustion on respiratory function and cutaneous histamine and neuropeptide contents of "Feishu" (BL13) in asthmatic rats].
Topics: Animals; Asthma; Histamine; Moxibustion; Rats; Rats, Sprague-Dawley; Vasoactive Intestinal Peptide | 2020 |
Neuroinflammatory Gene Expression Pattern Is Similar between Allergic Rhinitis and Atopic Dermatitis but Distinct from Atopic Asthma.
Topics: Adolescent; Asthma; Child; Dermatitis, Atopic; Female; Histamine; Humans; Inflammation; Male; Nerve | 2020 |
Therapeutic Potential of Antileukotriene Drug-
Topics: Animals; Anti-Asthmatic Agents; Antioxidants; Area Under Curve; Asthma; Camellia sinensis; Delayed-A | 2021 |
DM-induced Hypermethylation of IR and IGF1R attenuates mast cell activation and airway responsiveness in rats.
Topics: Allergens; Animals; Asthma; Biomarkers; Bronchial Hyperreactivity; Cytokines; Diabetes Mellitus, Exp | 2020 |
Administration of Lactobacillus paracasei HB89 mitigates PM2.5-induced enhancement of inflammation and allergic airway response in murine asthma model.
Topics: Animals; Asthma; Cytokines; Disease Models, Animal; Down-Regulation; Female; Histamine; Immunoglobul | 2020 |
Herb pair of Ephedrae Herba-Armeniacae Semen Amarum alleviates airway injury in asthmatic rats.
Topics: Acetylcholine; Animals; Apoptosis; Asthma; Disease Models, Animal; Drugs, Chinese Herbal; Ephedra si | 2021 |
ORMDL3 expression in ASM regulates hypertrophy, hyperplasia via TPM1 and TPM4, and contractility.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Calcium; Cell Proliferation; Cells, Cultured; Histamine; | 2021 |
Targeted inhibition of allergen-induced histamine production by neutrophils.
Topics: Allergens; Asthma; Case-Control Studies; Histamine; Histamine Release; Humans; Hypersensitivity; Imm | 2021 |
Identifying bronchoconstriction from the ratio of diaphragm EMG to tidal volume.
Topics: Adolescent; Adult; Aged; Asthma; Bronchial Hyperreactivity; Bronchoconstriction; Bronchodilator Agen | 2021 |
Mentha arvensis essential oil suppressed airway changes induced by histamine and ovalbumin in experimental animals.
Topics: Animals; Asthma; Bronchoconstriction; Disease Models, Animal; Dyspnea; Eosinophils; Female; Guinea P | 2018 |
Citrus tachibana Leaves Ethanol Extract Alleviates Airway Inflammation by the Modulation of Th1/Th2 Imbalance via Inhibiting NF-κB Signaling and Histamine Secretion in a Mouse Model of Allergic Asthma.
Topics: Animals; Anti-Asthmatic Agents; Asthma; Citrus; Disease Models, Animal; Histamine; Humans; Immunoglo | 2017 |
Nebivolol attenuates oxidative stress and inflammation in a guinea pig model of ovalbumin-induced asthma: a possible mechanism for its favorable respiratory effects.
Topics: Animals; Anti-Asthmatic Agents; Asthma; Biomarkers; Bronchoalveolar Lavage Fluid; Disease Models, An | 2018 |
The relation between nonspecific hyperreactivity of the airways and atopic constitution in asthmatics.
Topics: Administration, Inhalation; Adolescent; Adult; Asthma; Biomarkers; Bronchial Hyperreactivity; Bronch | 2016 |
FcγR/ROS/CK2α Is the Key Inducer of NF-κB Activation in a Murine Model of Asthma.
Topics: Allergens; Animals; Asthma; Casein Kinase II; Cytokines; Disease Models, Animal; Female; Histamine; | 2018 |
Modulation of allergic responses by mitochondrial STAT3 inhibitors.
Topics: Adenosine Triphosphate; Animals; Anti-Allergic Agents; Antigens; Asthma; Biomarkers; Caspase 3; Cell | 2018 |
Bronchoalveolar lavage fluid cytology and airway hyper-reactivity in clinically normal horses.
Topics: Animals; Asthma; Bronchoalveolar Lavage; Bronchoalveolar Lavage Fluid; Cross-Sectional Studies; Fema | 2018 |
Obesity increases airway smooth muscle responses to contractile agonists.
Topics: Adult; Asthma; Calcium; Carbachol; Cardiotonic Agents; Case-Control Studies; Cells, Cultured; Female | 2018 |
Nigella sativa as an anti-inflammatory agent in asthma.
Topics: Animals; Anti-Inflammatory Agents; Asthma; Ethanol; Histamine; Mast Cells; Nigella sativa; Peritonea | 2018 |
Montelukast Sodium Formulation Containing Green Tea Extract to Reduce the Oxidative Stress in Guinea Pig Model of Chronic Allergic Asthma.
Topics: Acetates; Administration, Oral; Animals; Anti-Asthmatic Agents; Asthma; Chronic Disease; Cyclopropan | 2018 |
Allergic rhinitis and asthma co-morbidity.
Topics: Asthma; Comorbidity; Dermatitis, Atopic; Eosinophilia; Histamine; Humans; Immunoglobulin E; Nitric O | 2019 |
Small airways in asthma: their independent contribution to the severity of hyperresponsiveness.
Topics: Adult; Asthma; Bronchi; Bronchial Hyperreactivity; Female; Forced Expiratory Volume; Histamine; Huma | 2013 |
Antigen-induced airway hyperresponsiveness in absence of broncho-obstruction in sensitized guinea pigs.
Topics: Airway Obstruction; Animals; Antigens; Asthma; Bronchoalveolar Lavage Fluid; Disease Models, Animal; | 2013 |
Activation of basophils by the double-stranded RNA poly(A:U) exacerbates allergic inflammation.
Topics: Animals; Asthma; Basophils; Biomarkers; Cells, Cultured; Cytokines; Disease Progression; Female; Flo | 2013 |
The disulfide bond between cysteine 10 and cysteine 34 is required for CCL18 activity.
Topics: Animals; Asthma; Basophils; Cell Line; Cell Movement; Chemokines, CC; CHO Cells; Cricetulus; Cystein | 2013 |
A nebulized complex traditional Chinese medicine inhibits Histamine and IL-4 production by ovalbumin in guinea pigs and can stabilize mast cells in vitro.
Topics: Animals; Asthma; Bronchoconstriction; Bronchodilator Agents; Drugs, Chinese Herbal; Guinea Pigs; His | 2013 |
Qingfei Xiaoyan Wan alleviates asthma through multi-target network regulation.
Topics: Acetylcholine; Animals; Asthma; Cluster Analysis; Drugs, Chinese Herbal; Electrophoresis, Gel, Two-D | 2013 |
Intranasal curcumin and its evaluation in murine model of asthma.
Topics: Administration, Intranasal; Animals; Anti-Asthmatic Agents; Asthma; Bronchoalveolar Lavage Fluid; Ce | 2013 |
Flavones derived from nature attenuate the immediate and late-phase asthmatic responses to aerosolized-ovalbumin exposure in conscious guinea pigs.
Topics: Airway Resistance; Allergens; Animals; Anti-Asthmatic Agents; Asthma; Bronchoalveolar Lavage Fluid; | 2014 |
Cheonggukjang ethanol extracts inhibit a murine allergic asthma via suppression of mast cell-dependent anaphylactic reactions.
Topics: Animals; Anti-Allergic Agents; Anti-Asthmatic Agents; Asthma; Bronchoalveolar Lavage Fluid; Female; | 2014 |
Systemic delivery of alpha-asarone with Kolliphor HS 15 improves its safety and therapeutic effect on asthma.
Topics: Allylbenzene Derivatives; Anaphylaxis; Animals; Anisoles; Anti-Asthmatic Agents; Asthma; Biological | 2015 |
Antigen 43/Fcε3 chimeric protein expressed by a novel bacterial surface expression system as an effective asthma vaccine.
Topics: Adhesins, Escherichia coli; Adoptive Transfer; Animals; Antibodies, Neutralizing; Asthma; Autoantibo | 2014 |
Chromones.
Topics: Ammi; Animals; Anti-Allergic Agents; Asthma; Chromones; Guinea Pigs; Histamine; Histamine Release; H | 2014 |
Implication of novel thiazolo-thiophene derivative (MCD-KV-10) for management of asthma.
Topics: Animals; Anti-Asthmatic Agents; Asthma; Cytokines; Guinea Pigs; Histamine; Lipoxygenases; Lung; Male | 2015 |
Inhibition of TRPM7 channels reduces degranulation and release of cytokines in rat bone marrow-derived mast cells.
Topics: Animals; Asthma; Bone Marrow Cells; Boron Compounds; Cell Degranulation; Cytokines; Female; Histamin | 2014 |
Genetic variation within the histamine pathway among patients with asthma--a pilot study.
Topics: Adult; Amine Oxidase (Copper-Containing); Asthma; Black or African American; Child; Female; Gene Fre | 2015 |
The histamine H4 -receptor (H4 R) regulates eosinophilic inflammation in ovalbumin-induced experimental allergic asthma in mice.
Topics: Adoptive Transfer; Allergens; Animals; Asthma; Bronchoalveolar Lavage Fluid; CD11c Antigen; Cytokine | 2015 |
LPS exacerbates functional and inflammatory responses to ovalbumin and decreases sensitivity to inhaled fluticasone propionate in a guinea pig model of asthma.
Topics: Administration, Inhalation; Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid | 2015 |
IgE and IgA produced by OX40-OX40L or CD40-CD40L interaction in B cells-mast cells re-activate FcεRI or FcαRI on mast cells in mouse allergic asthma.
Topics: Animals; Antigens, CD; Antigens, Differentiation; Asthma; B-Lymphocytes; CD40 Antigens; CD40 Ligand; | 2015 |
A fungal protease allergen provokes airway hyper-responsiveness in asthma.
Topics: Administration, Inhalation; Allergens; Animals; Aspergillus fumigatus; Asthma; Bacterial Proteins; B | 2015 |
Genetic Variation along the Histamine Pathway in Children with Allergic versus Nonallergic Asthma.
Topics: Adolescent; Amine Oxidase (Copper-Containing); Asthma; Black or African American; Child; Female; Gen | 2015 |
Prostaglandin E2 inhibits mast cell-dependent bronchoconstriction in human small airways through the E prostanoid subtype 2 receptor.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Asthma; Azetidines; Bridged Bicy | 2015 |
Usefulness of impulse oscillometry for the assessment of airway hyperresponsiveness in mild-to-moderate adult asthma.
Topics: Adrenal Cortex Hormones; Adult; Aged; Airway Resistance; Area Under Curve; Asthma; Bronchial Hyperre | 2015 |
Consecutive Food and Respiratory Allergies Amplify Systemic and Gut but Not Lung Outcomes in Mice.
Topics: Allergens; Animals; Asthma; Cell Proliferation; Cytokines; Food Hypersensitivity; Histamine; Immunog | 2015 |
Lipopolysaccharide (LPS) exposure differently affects allergic asthma exacerbations and its amelioration by intranasal curcumin in mice.
Topics: Administration, Intranasal; Animals; Asthma; Curcumin; Cytokines; Histamine; Hypersensitivity; Immun | 2015 |
Adenosine monophosphate is not superior to histamine for bronchial provocation test for assessment of asthma control and symptoms.
Topics: Adenosine Monophosphate; Administration, Inhalation; Adrenal Cortex Hormones; Adult; Asthma; Bronchi | 2017 |
The Association of BCG Vaccination with Atopy and Asthma in Adults.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Allergens; Asthma; BCG Vaccine; Bronchi; Dermatitis, Ato | 2015 |
Acute bronchospasm during passive exposure to bronchial provocation tests.
Topics: Acute Disease; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Cough; Dyspnea; Female; Forced | 2016 |
PHYSIOLOGIC AIRWAY RESPONSES TO INHALED HISTAMINE AND ACETYLCHOLINE IN PATIENTS WITH MILD ASTHMA AS ANALYZED BY FORCED OSCILLATION.
Topics: Acetylcholine; Asthma; Bronchi; Female; Histamine; Humans; Male; Middle Aged; Respiratory Function T | 2015 |
Longitudinal assessment of airway responsiveness from 1 month to 18 years in the PIAF birth cohort.
Topics: Adolescent; Asthma; Australia; Bronchi; Bronchial Provocation Tests; Child; Child, Preschool; Dose-R | 2015 |
Bidirectional Counterregulation of Human Lung Mast Cell and Airway Smooth Muscle β2 Adrenoceptors.
Topics: Adrenergic beta-2 Receptor Agonists; Albuterol; Asthma; Benzoxazines; Cell Adhesion Molecule-1; Cell | 2016 |
Effects of histamine H1 receptor signaling on glucocorticoid receptor activity. Role of canonical and non-canonical pathways.
Topics: Asthma; Corticosterone; Dermatitis, Atopic; Dexamethasone; HeLa Cells; Histamine; Histamine Agonists | 2015 |
Bronchodilatory, antitussive and anti-inflammatory effect of morin in the setting of experimentally induced allergic asthma.
Topics: Airway Resistance; Animals; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Antitussive Agents; Ast | 2016 |
Population pharmacokinetic/pharmacodynamic modeling of histamine response measured by histamine iontophoresis laser Doppler.
Topics: Adolescent; Adult; Algorithms; Asthma; Blood Flow Velocity; Child; Female; Histamine; Histamine Anta | 2016 |
Rosae Multiflorae Fructus Hot Water Extract Inhibits a Murine Allergic Asthma Via the Suppression of Th2 Cytokine Production and Histamine Release from Mast Cells.
Topics: Animals; Anti-Allergic Agents; Asthma; Cytokines; Fruit; Histamine; Histamine Release; Hypersensitiv | 2016 |
Histamine-secreting microbes are increased in the gut of adult asthma patients.
Topics: Adult; Asthma; Case-Control Studies; Feces; Female; Gastrointestinal Microbiome; Histamine; Host-Pat | 2016 |
Specific histamine binding activity of a new lipocalin from Hyalomma asiaticum (Ixodidae) and therapeutic effects on allergic asthma in mice.
Topics: Animals; Asthma; Cloning, Molecular; Disease Models, Animal; DNA, Complementary; Escherichia coli; G | 2016 |
Reduced allergic lung inflammation by root extracts from two species of Peucedanum through inhibition of Th2 cell activation.
Topics: Allergens; Animals; Anti-Asthmatic Agents; Apiaceae; Asthma; Bronchoalveolar Lavage Fluid; CD4-Posit | 2017 |
The Pathogenesis of Alcohol-Induced Airflow Limitation in Acetaldehyde Dehydrogenase 2-Deficient Mice.
Topics: Alcohol Drinking; Aldehyde Dehydrogenase, Mitochondrial; Animals; Asthma; Biomarkers; Disease Models | 2016 |
Quercetin inhalation inhibits the asthmatic responses by exposure to aerosolized-ovalbumin in conscious guinea-pigs.
Topics: Administration, Inhalation; Administration, Oral; Aerosols; Airway Resistance; Albuterol; Animals; A | 2008 |
Airway inflammation in exercise-induced bronchospasm occurring in athletes without asthma.
Topics: Adult; Age Factors; Asthma; Asthma, Exercise-Induced; Bronchial Hyperreactivity; Cohort Studies; Din | 2008 |
Occupational rhinitis and asthma due to crickets.
Topics: Adult; Allergens; Animals; Antigens; Asthma; Blotting, Western; Bronchial Provocation Tests; Complex | 2008 |
Utility of cough response during hypertonic histamine challenge in diagnosing asthma.
Topics: Administration, Inhalation; Adult; Area Under Curve; Asthma; Bronchial Provocation Tests; Cough; Dia | 2008 |
Effects of inhaled monoethanolamine on bronchoconstriction.
Topics: Aerosols; Air Pollutants, Occupational; Airway Obstruction; Airway Resistance; Animals; Asthma; Atro | 2009 |
Glucocorticoids inhibit degranulation of mast cells in allergic asthma via nongenomic mechanism.
Topics: Animals; Anti-Inflammatory Agents; Asthma; Cell Degranulation; Glucocorticoids; Guinea Pigs; Histami | 2008 |
Role of the cystic fibrosis transmembrane conductance channel in human airway smooth muscle.
Topics: Asthma; Bronchi; Calcium; Calcium Channel Blockers; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosi | 2009 |
Identification of higenamine in Radix Aconiti Lateralis Preparata as a beta2-adrenergic receptor agonist1.
Topics: Aconitum; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Alkaloids; Animals; Asthma; | 2008 |
Induction of late airway response was involved in serum antigen-specific immunoglobulin G in rats.
Topics: Administration, Inhalation; Animals; Antigens; Asthma; Bronchoalveolar Lavage Fluid; Bronchoconstric | 2008 |
Anti-histamine drugs in asthma.
Topics: Asthma; Histamine; Histamine Agents; Humans | 1948 |
The desensitizing action of histamine (decimilist) in the treatment of bronchial asthma and asthmatic bronchitis.
Topics: Asthma; Histamine; Histamine Antagonists; Humans | 1948 |
Anti-histamine drugs in asthma.
Topics: Asthma; Histamine; Histamine Antagonists; Humans | 1948 |
Measurement of vital capacity in asthmatic subjects receiving histamine and acetyl-beta-methyl choline; a clinical study.
Topics: Asthma; Biomedical Research; Choline; Histamine; Humans; Tidal Volume; Vital Capacity | 1948 |
Equally elevated concentrations of exhaled nitric oxide in nonatopic and low-sensitized atopic asthmatics.
Topics: Adolescent; Adult; Analysis of Variance; Asthma; Biomarkers; Breath Tests; Bronchial Provocation Tes | 2009 |
Bronchial hyperresponsiveness in a population of north Finland with no previous diagnosis of asthma or chronic bronchitis assessed with histamine and methacholine tests.
Topics: Adult; Aged; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchitis; Female; Fin | 2008 |
Enhanced goblet cell hyperplasia in HDC knockout mice with allergic airway inflammation.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Cell Differentiation; Chloride Channels; Cytokines; F | 2009 |
Piperine inhibits eosinophil infiltration and airway hyperresponsiveness by suppressing T cell activity and Th2 cytokine production in the ovalbumin-induced asthma model.
Topics: Alkaloids; Animals; Asthma; Benzodioxoles; Bronchial Hyperreactivity; Cytokines; Disease Models, Ani | 2009 |
Occupational asthma and the paper recycling industry.
Topics: Adult; Asthma; Bronchial Provocation Tests; Glutaral; Histamine; Humans; Hydroxylamine; Male; Occupa | 2009 |
Paradoxical conducting airway responses and heterogeneous regional ventilation after histamine inhalation in rabbit studied by synchrotron radiation CT.
Topics: Administration, Inhalation; Airway Obstruction; Animals; Asthma; Bronchi; Bronchoconstriction; Hista | 2009 |
NT-702 (parogrelil hydrochloride, NM-702), a novel and potent phosphodiesterase 3 inhibitor, suppress the asthmatic response in guinea pigs, with both bronchodilating and anti-inflammatory effects.
Topics: Animals; Anti-Inflammatory Agents; Antigens; Asthma; Bronchoconstriction; Bronchodilator Agents; Cel | 2009 |
[Study on the antitussive and antiasthmatic effects of Radix Fici Hirtae].
Topics: Acetylcholine; Anaphylaxis; Animals; Antitussive Agents; Asthma; Astragalus propinquus; Citric Acid; | 2009 |
Anti-asthmatic activity of phenolic compounds from the roots of Gastrodia elata Bl.
Topics: Airway Resistance; Animals; Asthma; Benzaldehydes; Benzoates; Bronchoalveolar Lavage Fluid; Eosinoph | 2010 |
Is asthma caused by atopy (positive skin prick tests)? Epidemiologic evidence suggests a negative answer.
Topics: Allergens; Asthma; Histamine; Humans; Hypersensitivity, Immediate; Immunoglobulin E; Prevalence; Ski | 2010 |
[Histamine intolerance mimics anorexia nervosa].
Topics: Anorexia Nervosa; Asthma; Diagnosis, Differential; Female; Food Hypersensitivity; Histamine; Humans; | 2010 |
Mediators in exhaled breath condensate after hypertonic saline challenge.
Topics: Adolescent; Adult; Aged; Asthma; Breath Tests; Bronchi; Bronchial Hyperreactivity; Bronchial Provoca | 2009 |
Pharmacology and immunological actions of a herbal medicine ASHMI on allergic asthma.
Topics: Airway Remodeling; Animals; Anti-Asthmatic Agents; Asthma; Bronchoalveolar Lavage Fluid; Chromatogra | 2010 |
Comparison of eNO and histamine hyperresponsiveness in diagnosing asthma in new referrals.
Topics: Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Female; Forced Expiratory Volume; Hi | 2010 |
Inhibitory effects of diterpene acids from root of Aralia cordata on IgE-mediated asthma in guinea pigs.
Topics: Airway Resistance; Animals; Aralia; Asthma; Bronchoalveolar Lavage Fluid; Diterpenes; Dose-Response | 2010 |
Histamine induces Th2 activation through the histamine receptor 1 in house dust mite rhinitic but not asthmatic patients.
Topics: Adult; Allergens; Antigens, Dermatophagoides; Arthropod Proteins; Asthma; Cells, Cultured; Cysteine | 2010 |
Mannitol and AMP do not induce bronchoconstriction in eosinophilic bronchitis: further evidence for dissociation between airway inflammation and bronchial hyperresponsiveness.
Topics: Adenosine Monophosphate; Administration, Inhalation; Adult; Asthma; Bronchial Hyperreactivity; Bronc | 2010 |
Glutathione prevents the early asthmatic reaction and airway hyperresponsiveness in guinea pigs.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Disease Models, Animal; Glutathione; Guinea Pigs; Histam | 2010 |
Effect of various drugs on experimental asthma produced in guinea pigs by exposure to atomized histamine.
Topics: Animals; Asthma; Guinea Pigs; Histamine; Histamine Agents | 1946 |
Utility of hypertonic histamine challenge in distinguishing difficult-to-diagnose asthma.
Topics: Adult; Aged; Asthma; Bronchial Provocation Tests; Diagnosis, Differential; Female; Forced Expiratory | 2007 |
FcepsilonRI-alpha siRNA inhibits the antigen-induced activation of mast cells.
Topics: Allergens; Animals; Antigens; Asthma; Basophils; Cell Degranulation; Cell Line; Gene Expression Regu | 2009 |
Bronchial hyperresponsiveness to histamine correlates with airway remodelling in adults with asthma.
Topics: Acetylcholine; Adult; Aged; Airway Remodeling; Asthma; Bronchial Hyperreactivity; Bronchoscopy; Eosi | 2010 |
Effect of parenchymal stiffness on canine airway size with lung inflation.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Dogs; Elasticity; Histamine; Inhalation; Lung; Muscle Co | 2010 |
Histamine and methacholine challenge cut points.
Topics: Administration, Inhalation; Adult; Asthma; Bronchial Provocation Tests; Female; Histamine; Humans; M | 2010 |
Assessment of inhaled corticosteroid treatment response in asthma using hypertonic histamine challenge-induced cough.
Topics: Administration, Inhalation; Adult; Aged; Asthma; Beclomethasone; Bronchial Provocation Tests; Case-C | 2010 |
Partial characterization of red gram (Cajanus cajan L. Millsp) polypeptides recognized by patients exhibiting rhinitis and bronchial asthma.
Topics: Allergens; Anaphylaxis; Animals; Asthma; Cajanus; Cells, Cultured; Cross Reactions; Cytokines; Elect | 2010 |
Molecular modeling and QSAR studies of a set of indole and benzimidazole derivatives as H₄ receptor antagonists.
Topics: Algorithms; Anti-Inflammatory Agents; Asthma; Benzimidazoles; Drug Design; Histamine; Histamine Anta | 2011 |
TPI 1020, a novel anti-inflammatory, nitric oxide donating compound, potentiates the bronchodilator effects of salbutamol in conscious guinea-pigs.
Topics: Administration, Inhalation; Adrenergic beta-Agonists; Albuterol; Animals; Anti-Inflammatory Agents; | 2010 |
Can AMP induce sputum eosinophils, even in subjects with complete asthma remission?
Topics: Adenosine Monophosphate; Adult; Aged; Anti-Asthmatic Agents; Asthma; Bronchial Hyperreactivity; Bron | 2010 |
Increased synthesis of vascular endothelial growth factor in allergic airway inflammation in histidine decarboxylase knockout (HDC(-/-)) mice.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Female; Histamine; Histidine Decarboxylase; Lung; Mic | 2010 |
Anti-asthmatic effects of phenylpropanoid glycosides from Clerodendron trichotomum leaves and Rumex gmelini herbes in conscious guinea-pigs challenged with aerosolized ovalbumin.
Topics: Airway Resistance; Albuterol; Animals; Anti-Asthmatic Agents; Asthma; Bronchoalveolar Lavage Fluid; | 2011 |
Bronchial reactivity to histamine is correlated with airway remodeling in adults with moderate to severe asthma.
Topics: Acetylcholine; Airway Remodeling; Asthma; Basement Membrane; Betamethasone; Bronchi; Bronchial Hyper | 2010 |
A case of anaphylactic reaction following matsutake mushroom ingestion: demonstration of histamine release reaction of basophils.
Topics: Adult; Agaricales; Anaphylaxis; Animals; Antigens, Dermatophagoides; Antigens, Plant; Asthma; Basoph | 2010 |
Suppression of ovalbumin-induced Th2-driven airway inflammation by β-sitosterol in a guinea pig model of asthma.
Topics: Acetylcholine; Animals; Anti-Asthmatic Agents; Asthma; Body Weight; Bronchial Spasm; Bronchoalveolar | 2011 |
Intratracheal sensitization/challenge-induced biphasic asthmatic response and airway hyperresponsiveness in guinea pigs.
Topics: Airway Resistance; Animals; Anti-Asthmatic Agents; Antigens; Asthma; Bronchial Hyperreactivity; Chro | 2010 |
A rat model of exercise-induced asthma: a nonspecific response to a specific immunogen.
Topics: Animals; Asthma; Bronchoconstriction; Cytokines; Disease Models, Animal; Histamine; Immunoglobulin E | 2011 |
Cough reflex sensitivity and airway inflammation in patients with chronic cough due to non-acid gastro-oesophageal reflux.
Topics: Adult; Aged; Asthma; Capsaicin; Chronic Disease; Cough; Cross-Sectional Studies; Female; Gastroesoph | 2011 |
Dichrostachys cinerea (L.) Wight et Arn (Mimosaceae) hydro-alcoholic extract action on the contractility of tracheal smooth muscle isolated from guinea-pig.
Topics: Animals; Asthma; Atropine; Dose-Response Relationship, Drug; Fabaceae; Guinea Pigs; Histamine; Hista | 2011 |
Regulation of mucosal mast cell activation by short interfering RNAs targeting syntaxin4.
Topics: Airway Obstruction; Animals; Animals, Genetically Modified; Asthma; Bronchi; Cell Degranulation; Cel | 2012 |
Potential allergens of green gram (Vigna radiata L. Millsp) identified as members of cupin superfamily and seed albumin.
Topics: Adult; Albumins; Allergens; Animals; Asthma; Cytokines; Fabaceae; Female; Food Hypersensitivity; His | 2011 |
Asthma pregnancy alters postnatal development of chromaffin cells in the rat adrenal medulla.
Topics: Adrenal Medulla; Animals; Animals, Newborn; Asthma; Bronchoalveolar Lavage Fluid; Cell Differentiati | 2011 |
Synthesis and antihistamine evaluations of novel loratadine analogues.
Topics: Animals; Anti-Allergic Agents; Asthma; Guinea Pigs; Histamine; Histamine Antagonists; Ileum; Loratad | 2011 |
Comparison of metabolites in exhaled breath and bronchoalveolar lavage fluid samples in a mouse model of asthma.
Topics: Animals; Arachidonic Acid; Asthma; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Exhalation; | 2011 |
NCS 613, a potent and specific PDE4 inhibitor, displays anti-inflammatory effects on human lung tissues.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Anti-Inflammatory Agents; Asthma | 2011 |
Actual control state of intermittent asthma classified on the basis of subjective symptoms.
Topics: Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Exhalation; Female; Forced Ex | 2011 |
Cortex Mori Radicis extract exerts antiasthmatic effects via enhancement of CD4(+)CD25(+)Foxp3(+) regulatory T cells and inhibition of Th2 cytokines in a mouse asthma model.
Topics: Allergens; Animals; Anti-Asthmatic Agents; Asthma; Cytokines; Disease Models, Animal; Drugs, Chinese | 2011 |
Phytopharmacological evaluation and anti-asthmatic activity of Ficus religiosa leaves.
Topics: Acetylcholine; Aminophylline; Animals; Anti-Allergic Agents; Anti-Asthmatic Agents; Asthma; Bronchia | 2011 |
A potential nanomedicine consisting of heparin-loaded polysaccharide nanocarriers for the treatment of asthma.
Topics: Animals; Asthma; beta-Cyclodextrins; Cell Degranulation; Cell Survival; Chitosan; Drug Carriers; Dru | 2012 |
PGE(2) receptor (EP(4)) agonists: potent dilators of human bronchi and future asthma therapy?
Topics: Acetylcholine; Aged; Animals; Asthma; Bronchi; Bronchodilator Agents; Data Interpretation, Statistic | 2012 |
Histamine may induce airway remodeling through release of epidermal growth factor receptor ligands from bronchial epithelial cells.
Topics: Adult; Airway Remodeling; Amphiregulin; Asthma; Bronchi; Cell Differentiation; Cell Line; Cell Movem | 2012 |
Inhibition of allergic airway responses by heparin derived oligosaccharides: identification of a tetrasaccharide sequence.
Topics: Animals; Anti-Asthmatic Agents; Anticoagulants; Antigens, Helminth; Ascaris suum; Asthma; Bronchoalv | 2012 |
A case of histamine fish poisoning in a young atopic woman.
Topics: Adult; Animals; Asthma; Female; Food Contamination; Foodborne Diseases; Histamine; Humans; Hypersens | 2012 |
Liposomes prolong the therapeutic effect of anti-asthmatic medication via pulmonary delivery.
Topics: Administration, Inhalation; Albuterol; Analysis of Variance; Animals; Anti-Asthmatic Agents; Anura; | 2012 |
Investigation into the mechanism of anti-asthmatic action of Moringa oleifera.
Topics: Acetylcholine; Animals; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Bronchial Provocati | 2009 |
Spirometry and forced oscillations in the detection of airway hyperreactivity in asthmatic children.
Topics: Adolescent; Airway Resistance; Asthma; Bronchial Hyperreactivity; Bronchoconstriction; Child; Child, | 2012 |
Lipopolysaccharide enhances FcεRI-mediated mast cell degranulation by increasing Ca2+ entry through store-operated Ca2+ channels: implications for lipopolysaccharide exacerbating allergic asthma.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Calcium Channel Blockers; | 2012 |
Design, synthesis and antihistamine evaluations of several N-hydroxyalkyl desloratadine analogues.
Topics: Animals; Asthma; Chemistry Techniques, Synthetic; Drug Design; Female; Guinea Pigs; Histamine; Hista | 2012 |
Experimental model of allergic asthma.
Topics: Airway Resistance; Animals; Asthma; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Citric Acid; | 2013 |
Polyphenols and their components in experimental allergic asthma.
Topics: Acetylcholine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Bronchial Hyperreactivity; | 2013 |
The effect of unilateral adrenalectomy on transformation of adrenal medullary chromaffin cells in vivo: a potential mechanism of asthma pathogenesis.
Topics: Adrenal Medulla; Adrenalectomy; Animals; Asthma; Bronchoconstriction; Chromaffin Cells; Corticostero | 2012 |
Mannitol challenge does not confirm bronchial hyperreactivity in some histamine-responsive asthmatic children.
Topics: Administration, Inhalation; Adolescent; Asthma; Bronchial Provocation Tests; Female; Forced Expirato | 2012 |
A comparison of antiasthma drugs between acute and chronic ovalbumin-challenged guinea-pig models of asthma.
Topics: Acute Disease; Administration, Inhalation; Administration, Oral; Aminopyridines; Androstadienes; Ani | 2012 |
Broncho-alveolar inflammation in cork worker's asthma.
Topics: Adult; Allergens; Asthma; Bronchi; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Bronch | 2002 |
Comparison of bronchial responsiveness to histamine in asthma, allergic rhinitis and allergic sensitization at the age of 7 years.
Topics: Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstrictor Agents; Case-Cont | 2002 |
Threshold levels of purified natural Bos d 2 for inducing bronchial airway response in asthmatic patients.
Topics: Adult; Agricultural Workers' Diseases; Allergens; Animals; Antibodies; Antigens, Plant; Asthma; Bron | 2002 |
Fasting stress exacerbates classical conditioned histamine release in guinea pigs.
Topics: Animals; Asthma; Bronchoconstriction; Conditioning, Classical; Disease Models, Animal; Food Deprivat | 2002 |
Subject discomfort associated with the histamine challenge in a population study.
Topics: Adult; Asthma; Histamine; Humans; Hypersensitivity; Patient Satisfaction; Research; Surveys and Ques | 2002 |
Disruption of L-histidine decarboxylase reduces airway eosinophilia but not hyperresponsiveness.
Topics: Administration, Inhalation; Airway Resistance; Animals; Asthma; Bone Marrow Cells; Bronchial Hyperre | 2003 |
[Pharmacological study on asthma-relieving decoction (dingchuan tang) treating asthma].
Topics: Acetylcholine; Animals; Anti-Asthmatic Agents; Asthma; Drug Combinations; Drugs, Chinese Herbal; Eph | 1999 |
Sibling effect on atopy in children of patients with asthma.
Topics: Adolescent; Adult; Allergens; Asthma; Birth Order; Bronchial Hyperreactivity; Family Characteristics | 2003 |
[Asthma patients' perception of dyspnea during acute bronchoconstriction].
Topics: Acute Disease; Adolescent; Adult; Aged; Anxiety; Asthma; Bronchial Provocation Tests; Bronchoconstri | 2003 |
Enhanced serum neutrophil chemotactic activity was noted in both early and late asthmatic responses during lysine-aspirin bronchoprovocation test in ASA-sensitive asthmatic patients.
Topics: Adult; Aged; Aspirin; Asthma; Bronchial Provocation Tests; Chemotactic Factors; Chemotaxis; Female; | 2003 |
Similar levels of nitric oxide in exhaled air in non-asthmatic rhinitis and asthma after bronchial allergen challenge.
Topics: Administration, Inhalation; Adult; Allergens; Asthma; Bronchial Provocation Tests; Bronchodilator Ag | 2003 |
[Effect of fexofenadine--selective antagonist of histamine receptor (H1) on histamine-induced bronchoconstriction].
Topics: Adult; Anti-Allergic Agents; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Dose-Response | 2003 |
Effect of rapid eye movement sleep deprivation on allergen-induced airway responses in a rat model of asthma.
Topics: Allergens; Animals; Asthma; Bronchoalveolar Lavage Fluid; Histamine; Immunity; Male; Models, Animal; | 2003 |
Persistence of bronchial reactivity to occupational agents after removal from exposure and identification of associated factors.
Topics: Asthma; Bronchi; Bronchial Hyperreactivity; Histamine; Humans; Immunization; Methacholine Chloride; | 2003 |
Inhalation challenge with bovine dander allergens: who needs it?
Topics: Adult; Agricultural Workers' Diseases; Allergens; Animals; Asthma; Bronchial Provocation Tests; Catt | 2003 |
Lung function in asthma: relation to clinics, challenge tests and immunotherapy.
Topics: Adolescent; Adult; Allergens; Asthma; Bronchial Provocation Tests; Desensitization, Immunologic; Fem | 2003 |
Sex differences in asthma, atopy, and airway hyperresponsiveness in a university population.
Topics: Adult; Allergens; Asthma; Bronchial Hyperreactivity; Female; Histamine; Humans; Hypersensitivity, Im | 2003 |
Histamine deficiency in gene-targeted mice strongly reduces antigen-induced airway hyper-responsiveness, eosinophilia and allergen-specific IgE.
Topics: Analysis of Variance; Animals; Asthma; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Ch | 2003 |
[Experimental study of histaminic asthma].
Topics: Asthma; Histamine; Histamine Agents | 1952 |
[Specific pharmacological applicability of histamine-antigen asthma in the guinea pig].
Topics: Antigens; Asthma; Guinea Pigs; Histamine | 1953 |
[Variations in the histamine-fixing power of the serum induced in the allergic man in the guinea pig by the injection of normal human serum].
Topics: Asthma; Blood; Guinea Pigs; Histamine; Humans; Injections; Male; Serum | 1953 |
[The behavior of the serum diastase in bronchial asthma, in anaphylactic and in histamine shock].
Topics: Amylases; Asthma; Glycoside Hydrolases; Histamine; Humans; Hypersensitivity; Immune System Diseases; | 1953 |
[Protective action of serum in relation to histamine].
Topics: Asthma; Blood; gamma-Globulins; Histamine; Serum | 1954 |
[ACTH and histamine-histidine in intradermal injections in gout, rheumatoid arthritis, rheumatic fever and asthma].
Topics: Adrenocorticotropic Hormone; Arthritis, Rheumatoid; Asthma; Gout; Histamine; Histidine; Injections, | 1954 |
The effect of some sympathicomimetic amines and enzyme blocking agents on asthma in the guinea pig induced by antigen or histamine aerosols.
Topics: Aerosols; Amines; Asthma; Enzymes; Guinea Pigs; Histamine; Sympathomimetics | 1954 |
Urinary excretion of histamine in patients having asthma and hay fever: observations on changes produced by administration of cortisone.
Topics: Asthma; Body Fluids; Cortisone; Histamine; Humans; Rhinitis, Allergic, Seasonal | 1954 |
Stresses and hypersensitivity; effect of adrenalectomy in the guinea pig on asthma from antigen and histamine aerosols and on its inhibition by a nonspecific substances, sodium nucleate.
Topics: Adrenal Glands; Adrenalectomy; Aerosols; Asthma; Guinea Pigs; Histamine; Histamine Agents; Hypersens | 1955 |
[Studies of the pancreas and the salivary glands in histamine induced asthma and in serum anaphylaxis].
Topics: Anaphylaxis; Asthma; Histamine; Hypersensitivity; Pancreas; Salivary Glands | 1956 |
[Effect of cortisone on allergenic pulmonary hypersensibility in asthmatic].
Topics: Acetylcholine; Allergens; Asthma; Cortisone; Histamine; Humans; Lung | 1956 |
[Effect of cortisone on allergenic pulmonary hypersensibility in asthmatic].
Topics: Acetylcholine; Allergens; Asthma; Cortisone; Histamine; Humans; Lung | 1956 |
[Effect of cortisone on allergenic pulmonary hypersensibility in asthmatic].
Topics: Acetylcholine; Allergens; Asthma; Cortisone; Histamine; Humans; Lung | 1956 |
[Effect of cortisone on allergenic pulmonary hypersensibility in asthmatic].
Topics: Acetylcholine; Allergens; Asthma; Cortisone; Histamine; Humans; Lung | 1956 |
Asthmatic dyspnea caused by the release of endogenous histamine.
Topics: Asthma; Dyspnea; Histamine; Humans; Medical Records | 1956 |
Asthmatic dyspnea caused by the release of endogenous histamine.
Topics: Asthma; Dyspnea; Histamine; Humans; Medical Records | 1956 |
Asthmatic dyspnea caused by the release of endogenous histamine.
Topics: Asthma; Dyspnea; Histamine; Humans; Medical Records | 1956 |
Asthmatic dyspnea caused by the release of endogenous histamine.
Topics: Asthma; Dyspnea; Histamine; Humans; Medical Records | 1956 |
Diagnostic use of alterations in eosinophils after injection of histamine into allergic patients.
Topics: Asthma; Eosinophils; Histamine; Humans; Leukocyte Count | 1956 |
Diagnostic use of alterations in eosinophils after injection of histamine into allergic patients.
Topics: Asthma; Eosinophils; Histamine; Humans; Leukocyte Count | 1956 |
Diagnostic use of alterations in eosinophils after injection of histamine into allergic patients.
Topics: Asthma; Eosinophils; Histamine; Humans; Leukocyte Count | 1956 |
Diagnostic use of alterations in eosinophils after injection of histamine into allergic patients.
Topics: Asthma; Eosinophils; Histamine; Humans; Leukocyte Count | 1956 |
Histamine therapy for chronic Bronchial asthma.
Topics: Asthma; Histamine; Humans | 1957 |
[Induction of typical asthma in guinea pigs; histamine-choline synergy].
Topics: Acetylcholine; Animals; Asthma; Choline; Guinea Pigs; Histamine; Histamine Agents; Parasympathomimet | 1956 |
[Clinical results obtained with a new synthetic histamine: methylaminophenylthienylpiperidine tartrate (sandostene)].
Topics: Asthma; Calcium; Dermatitis; Dermatitis, Contact; Histamine; Histamine H1 Antagonists; Tartrates | 1957 |
The effect of corticosteroid administration upon blood histamine content.
Topics: Adrenal Cortex Hormones; Arthritis; Arthritis, Rheumatoid; Asthma; Eosinophilia; Histamine; Humans; | 1957 |
The influence of histamine and adrenaline on the vital capacity.
Topics: Asthma; Epinephrine; Histamine; Histamine Agents; Humans; Respiration; Tidal Volume; Vital Capacity | 1957 |
[Desensitizing treatment of asthma by means of massage, which provokes the formation of endogenous histamine].
Topics: Asthma; Desensitization, Immunologic; Histamine; Humans; Massage; Mental Disorders | 1957 |
[Cholinergic-histaminic pulmonary hypersensitivity of asthma; relationship with pulmonary allergen hypersensitivity].
Topics: Acetylcholine; Asthma; Histamine; Histamine Agents; Humans; Lung | 1958 |
[Influencing experimental histamine asthma and serum anaphylaxis].
Topics: Anaphylaxis; Asthma; Histamine; Humans; Hypersensitivity | 1958 |
Urinary excretion of histamine in bronchial asthma.
Topics: Asthma; Body Fluids; Histamine; Humans | 1958 |
[Studies on allergic terrain; blood adrenalin & histamine in hypotension of allergic subjects].
Topics: Asthma; Epinephrine; Histamine; Humans; Hypotension | 1958 |
[Studies on the part played by histamine in anaphylactic asthma and observations on the induction and behavior of asthmatic and circulatory symptoms of anaphylactic shock fragments in guinea pigs].
Topics: Anaphylaxis; Animals; Asthma; Blood Pressure; Blood Pressure Determination; Guinea Pigs; Histamine; | 1959 |
[Intolerance of histamine and histamine-liberator 48/80 in asthmatics measured by the criterion of the asthmogenic threshold].
Topics: Asthma; Histamine; Histamine Agents; Histamine Release; Humans | 1959 |
[The treatment of allergic patients with histaglobine].
Topics: Asthma; gamma-Globulins; Globulins; Histamine; Humans | 1961 |
Mast cells in bronchial connective tissue of man: their modifications in asthma and after treatment with the histamine liberator 48/80.
Topics: Asthma; Connective Tissue; Histamine; Histamine Release; Humans; Male; Mast Cells | 1961 |
[Research on the mechanism of action of a histamine-globulin complex in guinea in pigs].
Topics: Animals; Asthma; gamma-Globulins; Globulins; Guinea; Histamine; Research; Swine | 1961 |
[The effects of histamine and the process of histamine liberation on pulmonary function].
Topics: Asthma; Histamine; Histamine Release; Humans; Lung; Respiratory Function Tests; Respiratory Physiolo | 1960 |
[Treatment of asthma by subcutaneous injections of a mixture of gamma globulin and histamine].
Topics: Asthma; gamma-Globulins; Globulins; Histamine; Injections, Subcutaneous | 1960 |
[Comparative studies with new corticoid derivatives on histamine- and serotonin asthma in the guinea pig].
Topics: Adrenal Cortex Hormones; Analgesics; Asthma; Guinea Pigs; Histamine; Serotonin | 1960 |
[Comparative studies on the onset and duration of action of glucorticoids in histamine and serotonin asthma in guinea pigs].
Topics: Adrenal Cortex Hormones; Animals; Asthma; Guinea Pigs; Histamine; Serotonin | 1960 |
[Comparative research on the onset and duration of action of new dexamethasone and prednisolone esters on histamine and serotonin asthma in the guinea pig].
Topics: Asthma; Dexamethasone; Esters; Guinea Pigs; Histamine; Prednisolone; Serotonin | 1960 |
[Reflections on the discrepancy, in asthma, between the results of allergological tests and those of anti-allergic therapy].
Topics: Anti-Allergic Agents; Asthma; gamma-Globulins; Globulins; Histamine | 1961 |
[A histamine-globulin complex. First clinical results obtained in the treatment of asthma].
Topics: Asthma; gamma-Globulins; Globulins; Histamine | 1960 |
[Contribution to the treatment of asthma with a combination of gamma globulin and histamine].
Topics: Asthma; gamma-Globulins; Globulins; Histamine | 1960 |
[Therapeutic results in asthma of a gamma globulin-histamine complex].
Topics: Asthma; gamma-Globulins; Globulins; Histamine | 1959 |
[Therapeutic results in asthma of a gamma-globulin-histamine complex].
Topics: Asthma; gamma-Globulins; Globulins; Histamine | 1959 |
[Sensitization to the gamma globulin-histamine complex].
Topics: Asthma; gamma-Globulins; Globulins; Histamine; Hypersensitivity; Immune System Diseases; Nervous Sys | 1962 |
[Research on the role of the hypothalamohypophyso-adrenal system in the metabolism of histamine, in allergy and in bronchial asthma].
Topics: Adrenal Cortex; Amine Oxidase (Copper-Containing); Asthma; Histamine; Hypersensitivity; Hypothalamus | 1961 |
Effect of Nardostachys jatamansi fumes and aerosols in histamine-induced bronchial asthma in guinea pigs.
Topics: Administration, Inhalation; Aerosols; Animals; Asthma; Guinea Pigs; Histamine; Humans; Nardostachys; | 1961 |
Changes during 24 hours in the lung function and histamine hyperreactivity of the bronchial tree in asthmatic and bronchitic patients.
Topics: Asthma; Bronchitis; Histamine; Humans; Lung; Respiratory Function Tests; Trees | 1962 |
[Long-term results of histablobine in the treatment of asthma (apropos of 40 cases)].
Topics: Asthma; gamma-Globulins; Histamine | 1963 |
[On the range of error and interpretation of histaminopexy determination. Evaluation of a mass examination of 650 subjects].
Topics: Asthma; Histamine; Humans; Neurodermatitis | 1962 |
Effect of posture in experimental asthma in man.
Topics: Asthma; Histamine; Humans; Male; Posture; Respiratory Function Tests | 1963 |
[THE EFFECT OF ANTIPYRETIC AND ANALGESIC SUBSTANCES ON HUMAN BRONCHIAL ASTHMA AND EXPERIMENTAL ASTHMA IN GUINEA PIGS].
Topics: Acetylcholine; Aminopyrine; Analgesics; Analgesics, Non-Narcotic; Anaphylaxis; Animals; Antipyretics | 1963 |
[PROTECTIVE SERUM AND ASTHMA].
Topics: Asthma; Bronchitis; Dyspnea; Histamine; Humans; Immune Sera | 1963 |
[COMPARATIVE STUDY OF THE PROTECTION TEST AND EXPLORATION OF PULMONARY VENTILATION IN ASTHMA].
Topics: Acetylcholine; Asthma; Bronchial Diseases; Dyspnea; Epinephrine; Histamine; Humans; Isoproterenol; L | 1963 |
[GENERALITIES ON HISTAMINE-PROTECTION AND PROTECTIVE SERUMS].
Topics: Aerosols; Anti-Allergic Agents; Asthma; gamma-Globulins; Guinea Pigs; Histamine; Histamine H1 Antago | 1963 |
[PROTECTIVE SERUMS IN COMBINATION WITH CORTICOIDS AND GAMMA GLOBULINS].
Topics: Adrenal Cortex Hormones; Anti-Allergic Agents; Asthma; Chloroquine; gamma-Globulins; Histamine; Hist | 1963 |
[STUDIES ON HISTAMINE IN THE BLOOD OF CHILDREN. 3. ON HISTAMINE IN THE BLOOD IN ALLERGIC DISEASES].
Topics: Asthma; Blood Chemical Analysis; Child; Histamine; Humans; Hypersensitivity; Immune System Diseases; | 1963 |
[HYPERREACTIVITY OF THE BRONCHI IN PATIENTS WITH CHRONIC ASPECIFIC DISORDERS OF THE LOWER RESPIRATORY PASSAGES].
Topics: Asthma; Body Constitution; Bronchi; Bronchial Diseases; Bronchitis; Histamine; Humans; Pharmacology; | 1963 |
[OBSERVATIONS ON THE EFFECT OF GANGLIOPLEGICS ON CHANGES IN PULMONARY VENTILATION INDUCED BY HISTAMINE].
Topics: Adolescent; Asthma; Bronchial Spasm; Bronchitis; Ganglionic Blockers; Histamine; Humans; Pulmonary V | 1963 |
[USE OF THE ATROPINE TEST IN THE DIAGNOSIS OF ALLERGIC DISEASES].
Topics: Asthma; Atropine; Coombs Test; Eczema; Histamine; Humans; Hypersensitivity; Pruritus; Rhinitis, Alle | 1963 |
[DEFICIENCY OF HISTAMINOPEXIC POWER OF THE BLOOD AND HEREDITY IN ASTHMA].
Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Asthma; Blood Chemical Analysis; Calcium; Calciu | 1964 |
[A POLYCLINIC METHOD IN ASTHMA RESEARCH].
Topics: Asthma; Biomedical Research; Histamine; Humans; Isoproterenol; Military Medicine; Netherlands; Resea | 1964 |
BRONCHIAL HYPERREACTIVITY IN ASTHMATIC AND BRONCHITIC CHILDREN.
Topics: Asthma; Bronchial Hyperreactivity; Bronchitis; Catheterization; Child; Esophagus; Histamine; Humans; | 1964 |
[THE LATEX-HISTAMINE TEST, A CRITERION FOR ALLERGY].
Topics: Asthma; Bronchitis; Diagnosis; Hemagglutination Inhibition Tests; Histamine; Humans; Hypersensitivit | 1964 |
PROPHYLACTIC ACTION OF REGITINE IN EXPERIMENTAL HISTAMINIC AND ALLERGIC BRONCHIAL ASTHMA.
Topics: Animals; Asthma; Guinea Pigs; Histamine; Pharmacology; Phentolamine; Research; Respiratory Hypersens | 1964 |
IDENTIFICATION OF HISTAMINE METABOLITE 1-METHYL, 4-IMIDAZOLE ACETIC ACID IN HUMAN URINE AND ITS ABSENCE IN STATUS ASTHMATICUS.
Topics: Acetates; Adrenocorticotropic Hormone; Animals; Asthma; Autoradiography; Carbon Isotopes; Chromatogr | 1964 |
PHYSIOLOGIC ACTIONS OF HEPARIN NOT RELATED TO BLOOD CLOTTING.
Topics: Anti-Inflammatory Agents; Asthma; Blood Coagulation; Bronchitis; Connective Tissue; Eczema; Glycosam | 1964 |
[SYNTHESIS OF SEROTONIN-AZOPROTEINS. EXPERIMENTS ON SEROTONIN IMMUNITY].
Topics: Animals; Antigen-Antibody Reactions; Asthma; gamma-Globulins; Haptens; Histamine; Immune Sera; Immun | 1964 |
STUDIES ON ASTHMATIC CHILDREN.
Topics: Adolescent; Asthma; Blood; Child; Dermatitis; Dermatitis, Atopic; Dexamethasone; Drug Hypersensitivi | 1964 |
[ACETYLCHOLINE AND HISTAMINE BRONCHIAL SPASM IN NEURODERMATITIS AND CONTROL SUBJECTS].
Topics: Acetylcholine; Asthma; Bronchial Spasm; Histamine; Humans; Neurodermatitis; Pharmacology; Skin Tests | 1964 |
[THE HISTAMINE-LATEX AGGLUTINATION REACTION OF C. MIKOL, M. RENOUX AND F. P. MERKLEN IN VARIOUS BRONCHO-PNEUMOPATHIES].
Topics: Agglutination; Allergens; Asthma; Bronchial Diseases; Histamine; Humans; Latex; Latex Fixation Tests | 1964 |
RESERPINE AND ASTHMA (WITH A REVIEW OF THE LITERATURE).
Topics: Asthma; Biochemical Phenomena; Biochemistry; Catecholamines; Histamine; Hypersensitivity; Pharmacolo | 1964 |
HISTAMINE METABOLITES IN ASTHMA.
Topics: Asthma; Bronchiectasis; Histamine; Histocytochemistry; Humans; Lung; Lung Neoplasms; Metabolism; Tub | 1964 |
INFANTILE ECZEMA, ASTHMA AND HAY FEVER IN MONGOLISM.
Topics: Adolescent; Asthma; Child; Dermatitis, Atopic; Down Syndrome; Eczema; Histamine; Humans; Infant; Rhi | 1964 |
[BRONCHIAL REACTIVITY OF MAN TO HISTAMINE AND ACETYLCHOLINE AFTER CORTISONIC TREATMENT].
Topics: Acetylcholine; Aerosols; Asthma; Bronchi; Histamine; Humans; Male; Pharmacology; Prednisolone | 1964 |
[COMPARATIVE CHANGES IN DYNAMIC PULMONARY RESISTANCE INDUCED BY HISTAMINE AND BY HOUSE DUST EXTRACTS IN ASTHMA PATIENTS].
Topics: Asthma; Bronchi; Dust; Histamine; Humans; Lung; Pharmacology; Respiratory Function Tests | 1964 |
HISTAMINE IN HUMAN URINE.
Topics: Allergens; Asthma; Chemical Phenomena; Chemistry; Fasting; Fluids and Secretions; Histamine; Humans; | 1965 |
[BRONCHIAL SENSITIVITY TO HISTAMINE IN THE ASTHMATIC AS COMPARED WITH THAT OF THE NORMAL PERSON].
Topics: Adolescent; Aerosols; Asthma; Biomedical Research; Bronchi; Child; Histamine; Humans; Pharmacology; | 1965 |
[COMPARATIVE STUDIES ON HISTAMINE AND SEROTONIN ANTAGONISM OF MONOPHENYLBUTAZONE, DIMETHYLAMINOETHANOL BITARTRATE, ISOPROPYLANTIPYRINE, CARISOPRODOL, TRASYLOL, RESPLANT AND PITRESSIN IN THE GUINEA PIG ASTHMA TEST. 1].
Topics: Amino Alcohols; Antipyrine; Aprotinin; Arginine Vasopressin; Asthma; Carisoprodol; Deanol; Enzyme In | 1964 |
[The relation between allergic rhinitis and bronchial asthma and the reaction of sensitized tissue to histamine].
Topics: Anti-Allergic Agents; Asthma; Histamine; Histamine Agents; Histamine H1 Antagonists; Humans; Rhiniti | 1954 |
Studies on histamine in allergic patients.
Topics: Asthma; Histamine; Humans | 1955 |
[The early results of the treatment of asthma in adults with a combination of histamine and gamma globulin].
Topics: Adult; Asthma; gamma-Globulins; Histamine; Humans | 1960 |
Blood histamine in bronchial asthma.
Topics: Asthma; Histamine; Humans | 1959 |
[Experiences with histamine-azoprotein in the treatment of asthma].
Topics: Asthma; Azo Compounds; Histamine; Humans | 1962 |
Conjugates of ovalbumin and monomethoxypolyethylene glycol abolish late allergic responses and decrease IL-4 and IL-5 mRNA expression in the rat.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Histamine; Interferon-gamma; Int | 2003 |
Effect of phosphodiesterase-5 inhibitor, sildenafil (Viagra), in animal models of airways disease.
Topics: Airway Resistance; Allergens; Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Flu | 2004 |
Prostaglandin E2 in the expired breath condensate of patients with asthma.
Topics: Adult; Asthma; Breath Tests; Bronchial Provocation Tests; Dinoprostone; Forced Expiratory Volume; Hi | 2003 |
Parental allergic status influences the risk of developing allergic sensitization and an asthmatic-like phenotype in canine offspring.
Topics: Administration, Inhalation; Airway Resistance; Allergens; Ambrosia; Animals; Antibody Formation; Ast | 2003 |
Dust mite-induced asthma in cynomolgus monkeys.
Topics: Adenosine; Aerosols; Allergens; Animals; Asthma; Bronchial Provocation Tests; Cytokines; Disease Mod | 2004 |
Early and late bronchoconstrictions, airway hyper-reactivity, leucocyte influx and lung histamine and nitric oxide after inhaled antigen: effects of dexamethasone and rolipram.
Topics: Administration, Inhalation; Animals; Antigens; Asthma; Bronchial Hyperreactivity; Bronchoalveolar La | 2004 |
Airway responsiveness to beta-adrenergic agonist (salbutamol) in asthma.
Topics: Adrenergic beta-Agonists; Adult; Aged; Albuterol; Asthma; Bronchi; Bronchial Hyperreactivity; Bronch | 2003 |
Childhood factors that predict asthma in young adulthood.
Topics: Adolescent; Adult; Asthma; Child; Female; Histamine; Humans; Male; Prognosis; Respiratory Hypersensi | 2004 |
Intravascular catheterization studies of bronchial asthma. I. Histamine levels in arterial and mixed venous blood of asthmatic patients before and during induced attacks.
Topics: Arteries; Asthma; Catheterization; Histamine; Humans | 1950 |
[Application of histamine-azoprotein in internal medicine].
Topics: Asthma; Histamine; Humans; Internal Medicine | 1950 |
[Histaminase and rapid histamine destruction in asthma].
Topics: Amine Oxidase (Copper-Containing); Asthma; Histamine; Humans | 1950 |
Bronchial obstruction induced by allergens, histamine and acetyl-beta-methylcholinechloride.
Topics: Acetylcholine; Airway Obstruction; Allergens; Asthma; Bronchi; Bronchial Diseases; Histamine; Humans | 1951 |
[Effect of human serum from normal and asthmatic subjects on the biological activity of histamine].
Topics: Asthma; Histamine; Humans; Serum | 1951 |
[Histamine fixation by normal human serum. Lack of fixation by serum of asthmatic].
Topics: Asthma; Histamine; Histological Techniques; Humans; Serum | 1951 |
Contribution to the study of the reticulo endothelial origin of dust cells or alveolar macrophagi. VI. Some histochemical aspects in the lungs of normal guinea pigs, and others submitted to acetylcholine, histamine, or anaphylactic shock, and so-called ex
Topics: Acetylcholine; Anaphylaxis; Animals; Asthma; Dust; Guinea Pigs; Histamine; Humans; Lung | 1952 |
[Experimental studies on variations induced by ACTH in asthma produced by histamine and acetylcholine].
Topics: Acetylcholine; Adrenocorticotropic Hormone; Asthma; Histamine | 1952 |
Heme oxygenase attenuates allergen-induced airway inflammation and hyperreactivity in guinea pigs.
Topics: Allergens; Animals; Asthma; Bronchi; Bronchial Hyperreactivity; Bronchoconstriction; Enzyme Inhibito | 2004 |
Relationship between exhaled carbon monoxide and airway hyperresponsiveness in asthmatic patients.
Topics: Adult; Asthma; Breath Tests; Bronchial Hyperreactivity; Bronchial Provocation Tests; Carbon Monoxide | 2004 |
Arthropod-derived histamine-binding protein prevents murine allergic asthma.
Topics: Animals; Antigens; Arthropods; Asthma; Carrier Proteins; Eosinophils; Histamine; Interleukin-4; Inte | 2004 |
Parenteral and aerosol administration of antihistaminic agents in the treatment of severe bronchial asthma.
Topics: Aerosols; Asthma; Histamine; Humans | 1949 |
Histamine and the antihistaminic drugs.
Topics: Allergens; Anaphylaxis; Animals; Anti-Allergic Agents; Asthma; Guinea Pigs; Histamine; Humans; Hyper | 1950 |
The effect of dihydroergocornine on the pulmonary response to methacholine and histamine in subjects with bronchial asthma.
Topics: Asthma; Choline; Dihydroergocornine; Ergot Alkaloids; Histamine; Humans; Methacholine Chloride | 1950 |
ACTH therapy in bronchial asthma; histamine and methacholine tolerance in the acute experiment and during prolonged treatment.
Topics: Adrenocorticotropic Hormone; Asthma; Choline; Drug Tolerance; Histamine; Humans; Immune Tolerance; M | 1950 |
Increased releasability of skin mast cells after exercise in patients with exercise-induced asthma.
Topics: Adolescent; Adult; Analgesics, Opioid; Asthma; Exercise; Histamine; Humans; Male; Mast Cells; Morphi | 2004 |
Childhood factors associated with asthma remission after 30 year follow up.
Topics: Adolescent; Adult; Asthma; Child; Child, Preschool; Cohort Studies; Disease-Free Survival; Follow-Up | 2004 |
Urinary inflammatory mediators and inhalation of hypertonic saline in children.
Topics: Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstriction; Case-Control St | 2005 |
[The content of biogenic amines in the lymphocytes in bronchial asthma].
Topics: Adult; Asthma; Biogenic Amines; Fluorescence; Histamine; Humans; Lymphocytes; Middle Aged; Serotonin | 2004 |
[Design, synthesis and antiasthmatic activities of NO-donating seratrodast derivatives].
Topics: Acetylcholine; Animals; Anti-Asthmatic Agents; Asthma; Benzoquinones; Guanidines; Guinea Pigs; Hepta | 2004 |
Bimodal skin reactivity to histamine in atopic children in Singapore: influence of specific sensitizations.
Topics: Adolescent; Age Factors; Air Conditioning; Asian People; Asthma; Child; Child, Preschool; Dermatitis | 2004 |
No association of histamine- N-methyltransferase polymorphism with asthma or bronchial hyperresponsiveness in two German pediatric populations.
Topics: Adolescent; Asthma; Bronchial Hyperreactivity; Child; Child, Preschool; Cohort Studies; Follow-Up St | 2005 |
Determinants of airway responsiveness to histamine in children.
Topics: Age Distribution; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Child; Cohort Stud | 2005 |
Histamine and indirect bronchoprovocation with adenosine monophosphate in asthma.
Topics: Adenosine Monophosphate; Asthma; Breath Tests; Bronchodilator Agents; Cysteine; Histamine; Humans; L | 2005 |
In vivo PAF-induced airway eosinophil accumulation reduces bronchial responsiveness to inhaled histamine.
Topics: Administration, Inhalation; Animals; Asthma; Bronchi; Bronchial Hyperreactivity; Bronchoalveolar Lav | 2005 |
Early- and late-phase bronchoconstriction, airway hyper-reactivity and cell influx into the lungs, after 5'-adenosine monophosphate inhalation: comparison with ovalbumin.
Topics: Adenosine Monophosphate; Administration, Inhalation; Animals; Asthma; Bronchi; Bronchoconstriction; | 2005 |
Hypertonicity of the challenge solution may increase the diagnostic accuracy of histamine challenge.
Topics: Adult; Asthma; Bronchial Provocation Tests; Bronchoconstrictor Agents; Bronchodilator Agents; Case-C | 2005 |
Mechanisms of relaxant action of luteolin in isolated guinea pig trachea.
Topics: Animals; Asthma; Bronchodilator Agents; Carbachol; Dose-Response Relationship, Drug; Guinea Pigs; Hi | 2005 |
The contribution of mast cells to the late-phase of allergic asthma in rats.
Topics: Animals; Asthma; Blotting, Northern; Bronchoalveolar Lavage Fluid; Eosinophils; Histamine; Hypersens | 2005 |
Liriopis tuber inhibit OVA-induced airway inflammation and bronchial hyperresponsiveness in murine model of asthma.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Cytokines; Disease Models, Animal; Eosinophils; Histamin | 2005 |
A novel A1 adenosine receptor antagonist, L-97-1 [3-[2-(4-aminophenyl)-ethyl]-8-benzyl-7-{2-ethyl-(2-hydroxy-ethyl)-amino]-ethyl}-1-propyl-3,7-dihydro-purine-2,6-dione], reduces allergic responses to house dust mite in an allergic rabbit model of asthma.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Anti-Asthmatic Agents; Asthma; Bronchial Hype | 2005 |
Separation of bronchoconstriction from increased ventilatory drive in a nonhuman primate model of chronic allergic asthma.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstriction; Histam | 2005 |
[Resistance to antibiotics and histamine production at the bacteria, isolated from the stomatopharynx of the children with bronchial asthma].
Topics: Adolescent; Asthma; Candida; Child; Child, Preschool; Drug Resistance, Bacterial; Female; Gram-Negat | 2002 |
Outcome in adulthood of asymptomatic airway hyperresponsiveness to histamine and exercise-induced bronchospasm in childhood.
Topics: Adolescent; Asthma; Asthma, Exercise-Induced; Bronchial Hyperreactivity; Child; Denmark; Exercise Te | 2005 |
Inflammatory and bronchospastic factors in asthma exacerbations caused by upper respiratory tract infections.
Topics: Acute Disease; Asthma; Bronchial Hyperreactivity; Eosinophil Cationic Protein; Female; Glucocorticoi | 2005 |
TNF-alpha induces the late-phase airway hyperresponsiveness and airway inflammation through cytosolic phospholipase A(2) activation.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; | 2005 |
Recognition of asthma in adolescents and young adults: which objective measure is best?
Topics: Adolescent; Adrenergic beta-Agonists; Adult; Albuterol; Anti-Asthmatic Agents; Antigens; Asthma; Bro | 2005 |
Airway inflammation and cough sensitivity in cough-variant asthma.
Topics: Adult; Asthma; Biomarkers; Bronchial Provocation Tests; Capsaicin; Cell Count; Diagnosis, Differenti | 2005 |
Chronic mucus hypersecretion: a marker of asthma in young adults?
Topics: Adult; Asthma; Bronchial Provocation Tests; Chi-Square Distribution; Chronic Disease; Cross-Sectiona | 2005 |
Role of histamine in airway remodeling of asthmatic guinea pig.
Topics: Airway Remodeling; Animals; Asthma; Guinea Pigs; Histamine; Histamine Antagonists; Male; Ovalbumin; | 2005 |
Met-enkephalin effects on histamine-induced bronchoconstriction in guinea pigs.
Topics: Animals; Asthma; Bronchoconstriction; Dose-Response Relationship, Drug; Enkephalin, Methionine; Fema | 2005 |
Differences in the time course of proximal and distal airway response to inhaled histamine studied by synchrotron radiation CT.
Topics: Administration, Inhalation; Airway Obstruction; Animals; Asthma; Biomechanical Phenomena; Bronchi; B | 2006 |
Lesions in the suprachiasmatic nuclei suppress inflammatory mediators in sensitized rats.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Circadian Rhythm; Eosinophils; Histamine; Hypersensit | 2006 |
THE ACTION OF HISTAMINE ON THE RESPIRATORY TRACT IN NORMAL AND ASTHMATIC SUBJECTS.
Topics: Asthma; Histamine; Histamine Agents; Humans; Respiratory System | 1946 |
THE EFFECT OF ANTIHISTAMINE SUBSTANCES AND OTHER DRUGS ON HISTAMINE BRONCHOCONSTRICTION IN ASTHMATIC SUBJECTS.
Topics: Anaphylaxis; Asthma; Bronchoconstriction; Histamine; Histamine Antagonists; Hypersensitivity | 1946 |
COMPARATIVE ACTION OF ACETYL-BETA-METHYL CHOLINE AND HISTAMINE ON THE RESPIRATORY TRACT IN NORMALS, PATIENTS WITH HAY FEVER, AND SUBJECTS WITH BRONCHIAL ASTHMA.
Topics: Asthma; Choline; Histamine; Histamine Agents; Humans; Influenza, Human; Respiratory System; Rhinitis | 1947 |
The role of antihistamines in asthma management.
Topics: Asthma; Cetirizine; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Humans; Leukotriene | 2006 |
Passive sensitization increases histamine-stimulated calcium signaling and NF-kappaB transcription activity in bronchial epithelial cells.
Topics: Animals; Asthma; Bronchi; Calcium Signaling; Dose-Response Relationship, Drug; Epithelial Cells; Gui | 2006 |
Perception of dyspnea during exacerbation and histamine-related bronchoconstriction in patients with asthma.
Topics: Adult; Aged; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Dyspnea; Female; Histamine; H | 2006 |
Airway hyperresponsiveness induced by repetitive intraperitoneal injection of lipopolysacharide and the involvement of inflammation and nitric oxide in guinea pigs.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Calcium; Disease Models, Animal; Gene Expression Regu | 2006 |
Adenosine A1 receptor antagonist versus montelukast on airway reactivity and inflammation.
Topics: Acetates; Adenosine A1 Receptor Antagonists; Animals; Anti-Asthmatic Agents; Asthma; Bronchial Hyper | 2006 |
[Experimental studies on antitussive, expectorant and antiasthmatic effects of extract from Citrus grandis var. tomentosa].
Topics: Acetylcholine; Ammonia; Animals; Anti-Asthmatic Agents; Antitussive Agents; Asthma; Citric Acid; Cit | 2006 |
Differentiation between the sensory and affective aspects of histamine-induced bronchoconstriction in asthma.
Topics: Adolescent; Adult; Affect; Aged; Anxiety; Asthma; Attitude to Health; Bronchial Provocation Tests; B | 2007 |
Effects of the phosphodiestrase-4 inhibitor rolipram on lung resistance and inflammatory reaction in experimental asthma.
Topics: Animals; Anti-Inflammatory Agents; Asthma; Bronchoalveolar Lavage Fluid; Dexamethasone; Guinea Pigs; | 2006 |
Optimisation of the sensitisation conditions for an ovalbumin challenge model of asthma.
Topics: Allergens; Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Eosinophils; Gu | 2007 |
Validated safety predictions of airway responses to house dust mite in asthma.
Topics: Adult; Animals; Antigens, Dermatophagoides; Asthma; Bronchial Provocation Tests; Bronchoconstrictor | 2007 |
In vitro and in vivo evaluation of the anti-asthmatic activities of fractions from Pheretima.
Topics: Animals; Anti-Asthmatic Agents; Antitussive Agents; Asthma; Cough; Disease Models, Animal; Dose-Resp | 2007 |
Area under the maximum expiratory flow-volume curve--a sensitive parameter in the evaluation of airway patency.
Topics: Administration, Inhalation; Adolescent; Adult; Airway Resistance; Area Under Curve; Asthma; Bronchia | 2008 |
Fritillaria cirrhosa, Anemarrhena asphodeloides, Lee-Mo-Tang and cyclosporine a inhibit ovalbumin-induced eosinophil accumulation and Th2-mediated bronchial hyperresponsiveness in a murine model of asthma.
Topics: Anemarrhena; Animals; Anti-Asthmatic Agents; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lava | 2007 |
A dual antagonist for chemokine CCR3 receptor and histamine H1 receptor.
Topics: Animals; Anti-Allergic Agents; Anti-Inflammatory Agents; Asthma; Calcium Signaling; Capillary Permea | 2007 |
Comparison of gel contraction mediated by airway smooth muscle cells from patients with and without asthma.
Topics: Adult; Aged; Asthma; Blotting, Western; Bronchoconstriction; Cells, Cultured; Collagen; Female; Gels | 2007 |
[Bronchial reactivity to histamine].
Topics: Adolescent; Adult; Asthma; Bronchial Hyperreactivity; Child; Forced Expiratory Volume; Histamine; Hi | 1965 |
Mast cell regulation of airway smooth muscle function in asthma.
Topics: Asthma; Bronchi; Chemokine CCL5; Granulocyte-Macrophage Colony-Stimulating Factor; Histamine; Humans | 2007 |
Histamine and tryptase modulate asthmatic airway smooth muscle GM-CSF and RANTES release.
Topics: Adolescent; Adult; Aged; Asthma; Bronchi; Cells, Cultured; Chemokine CCL5; Chlorpheniramine; Dinopro | 2007 |
Short-term variability of airway caliber-a marker of asthma?
Topics: Adolescent; Adult; Aged; Airway Resistance; Asthma; Australia; Bronchial Hyperreactivity; Bronchial | 2007 |
The use of oscillometry as a measure of airway responsiveness in asthmatic children after histamine and methacholine bronchoprovocation with dosimeter-MedicAid and DeVilbiss nebulizers.
Topics: Adolescent; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Child; Female; Histamine | 2007 |
Histamine 4 receptor activation induces recruitment of FoxP3+ T cells and inhibits allergic asthma in a murine model.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; CD4 Antigens; Cell Movement; Cytokines; Disease Model | 2007 |
Effects of acetaldehyde on human airway constriction and inflammation.
Topics: Acetaldehyde; Administration, Oral; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; A | 2007 |
[Study of cellularity in bronchoalveolar fluid and bronchial reactivity to histamine in a model of asthma in guinea pig].
Topics: Allergens; Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Disease Models, | 2006 |
In vivo adenosine A(2B) receptor desensitization in guinea-pig airway smooth muscle: implications for asthma.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Asthma; Base Sequence; Bronchodilator Agents; | 2007 |
Activation of protease-activated receptor-2 reduces airways inflammation in experimental allergic asthma.
Topics: Allergens; Animals; Asthma; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Female; Histamine; In | 2007 |
Airways are more reactive to histamine than to methacholine in patients with mild airway hyperresponsiveness, regardless of atopy.
Topics: Adult; Asthma; Bronchi; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstrictor A | 2007 |
Effects of cyproheptadine and cetirizine on eosinophilic airway inflammation in cats with experimentally induced asthma.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Cat Diseases; Cats; Cetirizine; Cross-Over Studies; C | 2007 |
A comparative study of the action of various sympathomimetic amine aerosols in counteracting the dyspnea and bronchospasm induced by histamine and by acetyl-beta-methylcholine.
Topics: Adrenal Glands; Aerosols; Asthma; Bronchial Spasm; Choline; Dyspnea; Histamine; Histamine Agents; Me | 1949 |
Histamine and bronchial asthma.
Topics: Asthma; Blood; Histamine; Humans | 1949 |
Antihistamines in bronchial asthma.
Topics: Anti-Allergic Agents; Asthma; Histamine; Histamine Antagonists; Humans | 1949 |
Patterns of intrathoracic gas volume and airway resistance in children with asthma.
Topics: Airway Resistance; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Bronchoconstrictor Agen | 2007 |
How accurately should we estimate the anatomical source of exhaled nitric oxide?
Topics: Algorithms; Animals; Asthma; Diffusion; Histamine; Humans; Lung; Models, Anatomic; Nitric Oxide; Pul | 2008 |
Progress in allergy signal research on mast cells: the role of histamine in goblet cell hyperplasia in allergic airway inflammation - a study using the Hdc knockout mouse.
Topics: Animals; Asthma; Chloride Channels; Cytokines; Female; Goblet Cells; Histamine; Histidine Decarboxyl | 2008 |
MAP kinases mediate interleukin-13 effects on calcium signaling in human airway smooth muscle cells.
Topics: Asthma; Bronchoconstrictor Agents; Calcium Signaling; Cells, Cultured; Extracellular Signal-Regulate | 2008 |
Response to inhaled histamine in bronchial asthma and in byssinosis.
Topics: Asthma; Gossypium; Histamine; Humans; Hypersensitivity, Immediate; Pneumoconiosis | 1967 |
[Histamine in bronchial asthma in children].
Topics: Adolescent; Asthma; Child; Female; Histamine; Humans; Male | 1967 |
Utilization of changes in pulmonary resistance for the evaluation of bronchodilator drugs.
Topics: Aerosols; Animals; Asthma; Bronchodilator Agents; Dogs; Female; Histamine; Isoproterenol; Male; Pres | 1967 |
Role of autonomic nervous system and the cough reflex in the increased responsiveness of airways in patients with obstructive airway disease.
Topics: Adolescent; Adult; Aerosols; Asthma; Atropine; Autonomic Nervous System; Bronchitis; Carbon; Cough; | 1967 |
[Utilization of the latex-histamine reaction in the study of the allergic system in the child. Comment on 500 observations].
Topics: Adolescent; Agglutination Tests; Asthma; Bronchitis; Child; Child, Preschool; Dyspnea; Female; Hista | 1967 |
[Exposure to allergens, atopization and hypersensitivity to acetylcholine (Histamine)].
Topics: Acetylcholine; Asthma; Dermatitis, Atopic; Desensitization, Immunologic; Histamine; Humans; Hypersen | 1967 |
[Histamine in blood and urine during the corticoid therapy of bronchial asthma in childhood].
Topics: Adolescent; Asthma; Child; Child, Preschool; Female; Histamine; Humans; Male; Prednisone | 1967 |
Inhibitory effect of histamine-gamma globulin conjugate on IgE-mediated reactivity of human basophils.
Topics: Asthma; Basophils; Cells, Cultured; Dust; gamma-Globulins; Histamine; Histamine Release; Humans; Imm | 1984 |
Leukotriene E4-induced airway hyperresponsiveness of guinea pig tracheal smooth muscle to histamine and evidence for three separate sulfidopeptide leukotriene receptors.
Topics: Airway Resistance; Animals; Asthma; Guinea Pigs; Histamine; Leukotriene E4; Muscle Contraction; Musc | 1984 |
Mechanical and biochemical alterations in guinea-pig tracheae caused by sensitisation.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Airway Resistance; Animals; Asthma; Bronchi; Cyclic AMP; Dihydr | 1984 |
Dysregulation of mediator release in relation to bronchial asthma and bronchial hyperresponsiveness.
Topics: Asthma; Bronchial Diseases; Calcimycin; Calcium; Child; Child, Preschool; Deuterium; Deuterium Oxide | 1984 |
Occupational asthma without bronchial hyperresponsiveness.
Topics: Adult; Asthma; Bronchi; Bronchial Provocation Tests; Histamine; Humans; Male; Methacholine Chloride; | 1984 |
In vitro responses of human asthmatic airway and pulmonary vascular smooth muscle.
Topics: Allergens; Asthma; Bronchi; Capsaicin; Histamine; Humans; In Vitro Techniques; Leukotriene B4; Metha | 1984 |
Impaired in vitro beta-adrenergic granulocyte response in chronic obstructive pulmonary disease.
Topics: Adrenergic beta-Agonists; Adult; Aged; Asthma; Bronchodilator Agents; Glucuronidase; Granulocytes; H | 1980 |
Parainfluenza 3 infection blocks the ability of a beta adrenergic receptor agonist to inhibit antigen-induced contraction of guinea pig isolated airway smooth muscle.
Topics: Adrenergic beta-Agonists; Animals; Asthma; Benzyl Alcohols; Benzyl Compounds; Bronchi; Carbachol; Fe | 1981 |
The effects of histamine, antihistamines, isoproterenol and theophylline on the Fc and complement receptor functions of polymorphonuclear leukocytes in asthmatic children.
Topics: Adolescent; Asthma; Child; Child, Preschool; Cimetidine; Diphenhydramine; Histamine; Histamine H1 An | 1981 |
Mode of action of bronchodilating drugs on histamine-induced bronchoconstriction in asthmatic children.
Topics: Adolescent; Adrenergic beta-Agonists; Airway Resistance; Asthma; Bronchi; Bronchodilator Agents; Chi | 1981 |
[Protective effect of adrenergic alpha blockaders on posthistamine bronchial spasm].
Topics: Adrenergic alpha-Antagonists; Adult; Albuterol; Asthma; Bronchial Provocation Tests; Bronchial Spasm | 1981 |
Histamine, asthma, and nasal polyps.
Topics: Asthma; Histamine; Humans; Immunoglobulin E; Mast Cells; Nasal Polyps | 1982 |
Reduction of bronchial hyperreactivity during prolonged allergen avoidance.
Topics: Adult; Allergens; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Dust; Female; Histamine; Hos | 1982 |
Comparison between airways response to an alpha-adrenoceptor agonist and histamine in asthmatic and non-asthmatic subjects.
Topics: Adrenergic alpha-Agonists; Adult; Asthma; Forced Expiratory Volume; Histamine; Humans; Lung; Male; M | 1982 |
[Studies of an experimental model of asthma in monkeys. The effect of H1 and H2 histamine antagonists on bronchoconstriction induced by histamine and methacholine aerosol challenge].
Topics: Aerosols; Animals; Asthma; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Macaca; Ma | 1982 |
Functional depression of H2 histamine receptors in sheep with experimental allergic asthma.
Topics: Animals; Asthma; Chlorpheniramine; Female; Histamine; Histamine H1 Antagonists; Histamine H2 Antagon | 1983 |
Inflammatory mediators of asthma.
Topics: Asthma; Histamine; Humans; Leukotriene B4; Mast Cells; Prostaglandins; SRS-A | 1983 |
Airway hyperreactivity. Clinical treatment with drugs.
Topics: Acetylcholine; Adrenal Cortex Hormones; Adrenergic beta-Agonists; Asthma; Bronchial Provocation Test | 1983 |
[Tartrazine-induced asthma].
Topics: Asthma; Autacoids; Azo Compounds; Histamine; Humans; Male; Middle Aged; Neutrophils; Tartrazine | 1983 |
Beta-adrenoceptor agonist responses in the skin and lungs of asthmatic subjects.
Topics: Adrenergic beta-Agonists; Adult; Albuterol; Asthma; Endothelium; Forced Expiratory Volume; Histamine | 1984 |
Adrenergic receptors of normal and asthmatic airways.
Topics: Adrenergic alpha-Agonists; Albuterol; Asthma; Bronchial Spasm; Catecholamines; Dose-Response Relatio | 1984 |
Effect of alpha-adrenergic blockade on exercise-induced asthma and conditioned cold air.
Topics: Adrenergic alpha-Antagonists; Adult; Air Conditioning; Airway Resistance; Antigens; Asthma; Asthma, | 1984 |
Ethylenediamine-induced asthma.
Topics: Adult; Asthma; Ethylenediamines; Histamine; Histamine Release; Humans; Male; Occupational Diseases; | 1980 |
The effects of Haemophilus influenzae vaccination on anaphylactic mediator release and isoprenaline-induced inhibition of mediator release.
Topics: Anaphylaxis; Animals; Arachidonic Acids; Asthma; Autacoids; Bradykinin; Bronchial Spasm; Disease Mod | 1980 |
Anaphylactoid reaction to 50% solution of dextrose.
Topics: Aged; Anaphylaxis; Asthma; Child; Diabetes Complications; Diabetes Mellitus; Female; Glucose; Histam | 1980 |
Antigen-induced bronchial anaphylaxis in actively sensitized guinea-pigs: effect of long-term treatment with sodium cromoglycate and aminophylline.
Topics: Aminophylline; Anaphylaxis; Animals; Antibody Formation; Antigens; Asthma; Atropine; Bronchi; Cromol | 1981 |
Aging and serum immunoglobulin E levels, immediate skin tests, RAST.
Topics: Adolescent; Adult; Aging; Asthma; Child; Epitopes; Female; Histamine; Humans; Immunoglobulin E; Male | 1981 |
Histamine content of sputum from patients with asthma and chronic bronchitis.
Topics: Albuterol; Animals; Asthma; Bronchitis; Carcinoma, Bronchogenic; Chronic Disease; Guinea Pigs; Hista | 1982 |
The role of basophils in asthma. I. Sodium cromoglycate on histamine release and content.
Topics: Antibodies, Anti-Idiotypic; Asthma; Basophils; Cromolyn Sodium; Dose-Response Relationship, Immunolo | 1982 |
[A comparative pathophysiological study of bronchial asthma provoked by inhalation of histamine or acetylcholine with special reference to dynamics of histamine (author's transl)].
Topics: Acetylcholine; Adolescent; Adult; Aged; Asthma; Bronchial Provocation Tests; Female; Histamine; Hist | 1982 |
Comparison of effects of investigational compounds upon allergic phenomena in rodents in vivo and in human basophils in vitro.
Topics: Acetylcholine; Animals; Asthma; Basophils; Bronchi; Bronchodilator Agents; Guinea Pigs; Histamine; H | 1982 |
The role of histamine and noradrenaline in allergic and exercise induced asthma of childhood, and the effect of theophylline treatment.
Topics: Adolescent; Airway Resistance; Asthma; Asthma, Exercise-Induced; Child; Epinephrine; Female; Histami | 1982 |
Release of histamine from leucocytes and its determinants in vitro in relation to bronchial responsiveness to inhaled histamine and exercise in vivo.
Topics: Asthma; Asthma, Exercise-Induced; Bronchial Provocation Tests; Calcimycin; Child; Deuterium; Deuteri | 1982 |
Measurement of plasma histamine in asthma.
Topics: Acute Disease; Asthma; Asthma, Exercise-Induced; Forced Expiratory Volume; Histamine; Histamine Rele | 1983 |
Effect of influenza A virus on leukocyte histamine release.
Topics: Asthma; Basophils; Calcimycin; Histamine; Histamine Release; In Vitro Techniques; Influenza A virus; | 1983 |
Invited contribution: the study and practice of allergy in the USSR. Developmental aspects of pediatric allergy.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Antigens, Bacterial; Asthma; B-Lymphocytes; Catecholamin | 1983 |
Do human mast cells possess functional beta adrenoceptors in vivo?
Topics: Adult; Albuterol; Asthma; Female; Histamine; Histamine Release; Humans; Male; Mast Cells; Propranolo | 1983 |
Histamine level in the blood and in the lung tissue during anaphylactic reaction in guinea-pigs treated with hydrocortisone and sodium cromoglycate.
Topics: Anaphylaxis; Animals; Asthma; Cromolyn Sodium; Guinea Pigs; Histamine; Histamine Release; Hydrocorti | 1982 |
Exercise and isocapnic hyperventilation-induced bronchoconstriction in asthma: relevance of circulating basophils to measurements of plasma histamine.
Topics: Adult; Airway Resistance; Asthma; Asthma, Exercise-Induced; Basophils; Body Temperature Regulation; | 1984 |
Mediators in exercise-induced asthma.
Topics: Asthma; Asthma, Exercise-Induced; Basophils; Chemotactic Factors; Cromolyn Sodium; Female; Histamine | 1984 |
[External respiratory functions during treatment of chronic pneumonia complicated by bronchial asthma].
Topics: Adolescent; Adult; Aged; Asthma; Chronic Disease; Drug Combinations; Drug Therapy, Combination; Fema | 1984 |
Mast cells in bronchoalveolar lumen of patients with bronchial asthma.
Topics: Adult; Aged; Asthma; Bronchi; Cell Count; Histamine; Histamine Release; Humans; Mast Cells; Middle A | 1984 |
Physiological and immunological effects of chronic antigen exposure in immunized guinea pigs.
Topics: Animals; Asthma; Dose-Response Relationship, Immunologic; Guinea Pigs; Histamine; Histamine Release; | 1984 |
Altered leukocyte response in relation to the basic abnormality in children with asthma and bronchial hyperresponsiveness.
Topics: Asthma; Bronchi; Bronchial Provocation Tests; Calcimycin; Child; Deuterium; Deuterium Oxide; Female; | 1984 |
Effect of continuous positive airway pressure on respiratory mechanics and pattern of breathing in induced asthma.
Topics: Abdominal Muscles; Adult; Asthma; Bronchial Provocation Tests; Diaphragm; Functional Residual Capaci | 1982 |
Comparative effects of SCH 1000 and fenoterol after histamine-induced bronchoconstriction in asymptomatic asthmatics.
Topics: Adult; Asthma; Atropine Derivatives; Bronchi; Ethanolamines; Female; Fenoterol; Histamine; Humans; I | 1984 |
Correction of an in vitro immunoregulatory defect in atopic subjects by the immunostimulating drug fanetizole mesylate (CP-48,810).
Topics: Adjuvants, Immunologic; Adolescent; Adult; Asthma; Cells, Cultured; Child; Concanavalin A; Dermatiti | 1984 |
The shape of the dose-response curve to histamine in asthmatic and normal subjects.
Topics: Adult; Asthma; Bronchial Provocation Tests; Dose-Response Relationship, Drug; Female; Forced Expirat | 1984 |
Nocturnal asthma and changes in circulating epinephrine, histamine, and cortisol.
Topics: Adult; Asthma; Circadian Rhythm; Cyclic AMP; Epinephrine; Histamine; Humans; Hydrocortisone; Male; M | 1980 |
Characterization of adenylate cyclase activity in asthmatic neutrophil sonicates.
Topics: Adenylyl Cyclases; Adult; Aged; Asthma; Cyclic AMP; Dihydroalprenolol; Female; Histamine; Humans; Is | 1980 |
Effect of Bordetella pertussis vaccination in mice and the isolated tracheal response to isoprenaline.
Topics: Animals; Asthma; Bordetella pertussis; Carbachol; Histamine; Injections, Intraperitoneal; Isoprotere | 1980 |
Partial beta-adrenergic receptor blockade in experimental bronchial asthma.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Asthma; Cyclic AMP; Disease Models, Animal; Guinea Pig | 1980 |
[Histamine, cAMP and cGMP in the blood and plasma of patients with allergic bronchial asthma].
Topics: Adult; Asthma; Cyclic AMP; Female; Histamine; Humans; Male; Middle Aged; Respiratory Hypersensitivit | 1981 |
Pulmonary function and histaminemia after polymyxin B inhalation.
Topics: Adolescent; Adult; Aerosols; Airway Obstruction; Asthma; Female; Forced Expiratory Volume; Histamine | 1981 |
The inhibitory effect of isoproterenol and dibutyryl cyclic-AMP on the immediate skin reaction.
Topics: Asthma; Bucladesine; Dust; Histamine; Humans; Hypersensitivity, Immediate; Isoproterenol; p-Methoxy- | 1982 |
[Effect of polymyxin B inhalation test on blood histamine levels in bronchial asthma].
Topics: Asthma; Bronchial Provocation Tests; Histamine; Humans; Polymyxin B; Polymyxins | 1981 |
Mast cells and basophils: effector cells of inflammatory disorders in the lung.
Topics: Anaphylaxis; Arachidonic Acid; Arachidonic Acids; Asthma; Basophils; Cyclic AMP; Histamine; Humans; | 1981 |
Patholphysiology of asthmatic bronchoconstriction.
Topics: Asthma; Bronchi; Cyclic AMP; Histamine; Humans; Muscle Tonus; Muscle, Smooth; Receptors, Adrenergic, | 1982 |
Pharmacological abnormality in bronchial asthma and the role of respiratory pathogens.
Topics: Alprostadil; Asthma; Bronchi; Cyclic AMP; Histamine; Humans; Isoproterenol; Leukocytes; Muscle, Smoo | 1982 |
Effects of anti-asthmatic drugs on airway resistance and plasma level of cyclic AMP in guinea pig.
Topics: Airway Resistance; Animals; Asthma; Bronchodilator Agents; Cyclic AMP; Female; Guinea Pigs; Histamin | 1982 |
[A study on the control of blood levels of histamine by intravenous administration of steroids and synthetic ACTH in patients with bronchial asthma (author's transl)].
Topics: Adrenocorticotropic Hormone; Asthma; Dexamethasone; Female; Histamine; Hormones; Humans; Hydrocortis | 1982 |
Effects of chronic histamine and ovalbumin aerosols on pulmonary beta adrenergic receptors in sensitized guinea pigs.
Topics: Aerosols; Animals; Asthma; Guinea Pigs; Histamine; Lung; Male; Ovalbumin; Receptors, Adrenergic; Rec | 1982 |
The role of the adrenergic system in allergy and bronchial hyperreactivity.
Topics: Adolescent; Adult; Allergens; Asthma; Bronchial Provocation Tests; Cyclic AMP; Female; Histamine; Hu | 1982 |
Non-specific bronchial hyper-reactivity in workers exposed to toluene di-isocyanate, diphenyl methane di-isocyanate and colophony.
Topics: Asthma; Bronchi; Cyanates; Electronics; Environmental Exposure; Histamine; Humans; Isocyanates; Occu | 1982 |
Allergen challenge of lung tissue from asthmatics elicits bronchial contraction that correlates with the release of leukotrienes C4, D4, and E4.
Topics: Allergens; Arachidonic Acid; Arachidonic Acids; Asthma; Bronchial Spasm; Histamine; Humans; Leukotri | 1983 |
Specific allergen induces contraction of bronchi and formation of leukotrienes C4, D4, and E4 in human asthmatic lung.
Topics: Allergens; Asthma; Bronchi; Calcimycin; Histamine; Humans; In Vitro Techniques; Leukotriene E4; Lung | 1983 |
Interactions between beta-adrenergic activity and prostaglandin synthesis in control of airways bronchoconstrictor responsiveness.
Topics: Adult; Airway Resistance; Albuterol; Asthma; Bronchi; Female; Histamine; Humans; Indomethacin; Male; | 1983 |
Mast cells and asthma. The role of mast cell mediators in the pathogenesis of allergic asthma.
Topics: Airway Obstruction; Asthma; Bradykinin; Capillary Permeability; Histamine; Humans; Leukotriene E4; M | 1983 |
[The hyperreactive bronchial system. Physiopathology and therapeutic possibilities].
Topics: Adrenal Cortex Hormones; Allergens; Asthma; Bronchi; Epithelium; Granulocytes; Histamine; Humans; Le | 1983 |
Comparison of beta 2-adrenoceptor stimulation in bronchial and skeletal muscle in experimental and clinical studies.
Topics: Albuterol; Animals; Asthma; Bronchi; Cats; Guinea Pigs; Histamine; Humans; Muscle, Smooth; Muscles; | 1984 |
New thoughts about the mechanisms of action of corticosteroids and theophylline in asthma.
Topics: Adrenal Cortex Hormones; Airway Resistance; Asthma; Bronchial Provocation Tests; Cyclic AMP; Histami | 1984 |
[Effect of beta-adrenergic mimetics and histamine on the capacity of T-lymphocytes from asthmatic patients and healthy persons to form E-rosettes].
Topics: Acetylcholine; Asthma; Bronchodilator Agents; Colchicine; Erythrocytes; Histamine; Humans; Leukocyte | 1984 |
Time course of the bronchoconstriction induced by inhaled histamine and methacholine.
Topics: Adolescent; Adult; Aerosols; Asthma; Bronchial Provocation Tests; Female; Forced Expiratory Volume; | 1983 |
Role of mediators in allergic and nonallergic asthma in dogs with hyperreactive airways.
Topics: Airway Resistance; Animals; Asthma; Bronchial Provocation Tests; Chromones; Citrates; Citric Acid; D | 1983 |
Mechanism of antigen-induced late asthmatic reactions.
Topics: Animals; Asthma; Bronchi; Bronchial Provocation Tests; Chemotactic Factors; Forced Expiratory Volume | 1983 |
Methods for assessing bronchial reactivity.
Topics: Allergens; Asthma; Bronchi; Bronchial Provocation Tests; Dinoprost; Gases; Histamine; Humans; Methac | 1983 |
Comparison of the tussive effects of histamine and methacholine in humans.
Topics: Adult; Aged; Asthma; Bronchial Spasm; Chronic Disease; Cough; Female; Histamine; Humans; Male; Metap | 1983 |
Decreased sensitivity and response of isolated tracheal muscle to methacholine and histamine without changing the activity of pulmonary muscarinic receptors in the egg albumin-sensitized guinea pig.
Topics: Animals; Asthma; Guinea Pigs; Histamine; Immunization; Lung; Methacholine Chloride; Methacholine Com | 1983 |
Comparison of airway reactivity induced by histamine, methacholine, and isocapnic hyperventilation in normal and asthmatic subjects.
Topics: Adult; Asthma; Bronchi; Bronchial Provocation Tests; Cold Temperature; Female; Forced Expiratory Vol | 1983 |
Effect of prior bronchoconstriction on the airway response to histamine in normal subjects.
Topics: Adult; Aerosols; Airway Resistance; Asthma; Bronchi; Bronchial Provocation Tests; Dose-Response Rela | 1984 |
Comparison of responsiveness to methacholine, histamine, and exercise in subgroups of asthmatic children.
Topics: Adolescent; Airway Resistance; Asthma; Bronchial Provocation Tests; Child; Female; Forced Expiratory | 1984 |
Methodological aspects of assessment of non-specific bronchial hyperreactivity.
Topics: Adult; Aged; Airway Resistance; Asthma; Bronchial Provocation Tests; Dose-Response Relationship, Dru | 1984 |
Inhalation challenge testing for asthma. Role of bronchial provocation tests in clinical practice.
Topics: Aerosols; Air; Asthma; Asthma, Exercise-Induced; Bronchial Provocation Tests; Cold Temperature; Forc | 1984 |
Cold air as a bronchial provocation technique. Reproducibility and comparison with histamine and methacholine inhalation.
Topics: Adolescent; Adult; Asthma; Bronchial Provocation Tests; Cold Temperature; Female; Histamine; Humans; | 1984 |
The relationship between bronchial hyperresponsiveness to methacholine and airway smooth muscle structure and reactivity.
Topics: Adult; Aged; Asthma; Bronchi; Carbachol; Female; Forced Expiratory Volume; Histamine; Humans; In Vit | 1984 |
Calcium channel blocking agents in bronchial hyperreactivity.
Topics: Airway Resistance; Asthma; Asthma, Exercise-Induced; Bronchial Provocation Tests; Bronchial Spasm; C | 1984 |
Studies on immunologic and inflammatory factors in the saliva and gingiva in patients with asthma.
Topics: Adult; Asthma; Child; Female; Gingiva; Gingival Crevicular Fluid; Gingivitis; Histamine; Humans; Hyp | 1984 |
Neutrophil chemotactic factor and exercise-induced asthma.
Topics: Asthma; Asthma, Exercise-Induced; Bronchial Provocation Tests; Chemotactic Factors; Cromolyn Sodium; | 1983 |
[Comparative evaluation of the effectiveness of sodium cromoglycate and ketotifen in bronchial asthma and their effect on blood histamine and polymyxin-induced bronchial spasm].
Topics: Asthma; Bronchial Spasm; Cromolyn Sodium; Female; Histamine; Humans; Ketotifen; Male; Polymyxin B | 1983 |
Sodium cromoglycate in histamine and methacholine reactivity in asthma.
Topics: Adolescent; Adult; Asthma; Bronchial Provocation Tests; Cromolyn Sodium; Histamine; Humans; Methacho | 1984 |
Effect of antihistamines and antiallergic drugs on responses to allergen and histamine provocation tests in asthma.
Topics: Adult; Allergens; Asthma; Bronchi; Bronchial Provocation Tests; Clemastine; Cromolyn Sodium; Double- | 1984 |
[Exercise-induced pathophysiological changes in asthmatic children. VII. Late asthmatic response in exercise-induced asthma: changes in chemical mediators and effects of the use of a mask and drugs].
Topics: Adolescent; Albuterol; Asthma; Asthma, Exercise-Induced; Chemotactic Factors; Child; Cromolyn Sodium | 1984 |
Allergies, mediators and asthma.
Topics: Airway Resistance; Arachidonic Acid; Arachidonic Acids; Asthma; Cromolyn Sodium; Histamine; Humans; | 1984 |
Effect of inhaled H1 and H2 receptor antagonist in normal and asthmatic subjects.
Topics: Adolescent; Adult; Airway Resistance; Asthma; Cimetidine; Clemastine; Female; Forced Expiratory Volu | 1980 |
Free histamine in nasal polyp fluid.
Topics: Aspirin; Asthma; Drug Hypersensitivity; Extracellular Space; Histamine; Humans; Hypersensitivity; Na | 1984 |
Histamine inhalation tests: inhalation of aerosol via a facemask versus a valve box with mouthpiece.
Topics: Adult; Aerosols; Asthma; Bronchial Provocation Tests; Histamine; Humans; Masks | 1984 |
The determination of blood histamine in asthmatic patients with a simple and sensitive method.
Topics: Adult; Asthma; Chromatography, High Pressure Liquid; Female; Fluorometry; Histamine; Humans; Male; M | 1984 |
Cardiac output and blood pressure in asthmatic children before and during induced asthma.
Topics: Adolescent; Albuterol; Asthma; Asthma, Exercise-Induced; Blood Pressure; Bronchi; Cardiac Output; Ch | 1984 |
Lung epithelial permeability: relation to nonspecific airway responsiveness.
Topics: Adult; Aerosols; Asthma; Capillary Permeability; Cell Membrane Permeability; Epithelium; Female; For | 1984 |
Occupational asthma in snow crab-processing workers.
Topics: Asthma; Brachyura; Bronchi; Bronchial Provocation Tests; Canada; Fish Products; Food-Processing Indu | 1984 |
Effects of calcium channel blockade on histamine induced bronchoconstriction in mild asthma.
Topics: Adult; Airway Resistance; Asthma; Bronchial Provocation Tests; Dose-Response Relationship, Drug; Dou | 1984 |
The action of prazosin and propylene glycol on methoxamine-induced bronchoconstriction in asthmatic subjects.
Topics: Adult; Aged; Asthma; Female; Forced Expiratory Volume; Histamine; Humans; Male; Methoxamine; Middle | 1984 |
Dopamine effect on bronchomotor tone in vivo.
Topics: Adult; Airway Resistance; Asthma; Bronchi; Bronchial Provocation Tests; Dopamine; Female; Forced Exp | 1984 |
Upper respiratory tract infections and airway reactivity in normal and asthmatic subjects.
Topics: Adult; Asthma; Bronchi; Bronchial Provocation Tests; Female; Forced Expiratory Volume; Histamine; Hu | 1984 |
The relationship of inhaled sulfur dioxide reactivity to ingested metabisulfite sensitivity in patients with asthma.
Topics: Adolescent; Adult; Aged; Asthma; Bronchi; Bronchial Provocation Tests; Dose-Response Relationship, D | 1984 |
A technique for monitoring respiratory responses in guinea pigs.
Topics: Animals; Animals, Laboratory; Asthma; Disease Models, Animal; Female; Guinea Pigs; Histamine; Microc | 1984 |
Histamine reactivity during the refractory period after exercise induced asthma.
Topics: Adult; Asthma; Asthma, Exercise-Induced; Bronchial Provocation Tests; Forced Expiratory Volume; Hist | 1984 |
Histamine phosphate has a cumulative effect when inhaled at five minute intervals.
Topics: Adult; Aerosols; Asthma; Bronchi; Bronchial Provocation Tests; Dose-Response Relationship, Drug; Dru | 1984 |
[Relationship between changes in plasma histamine levels and the location of the predominant site of exercise-induced asthma].
Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Female; Histamine; Humans; Male; Middle Aged; R | 1984 |
[Studies on exercise-induced bronchial lability (EIBL) in adult asthmatic patients].
Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Catecholamines; Female; Histamine; Humans; Male | 1984 |
[Clinical application of transcutaneous oxygen pressure determination in histamine inhalation test].
Topics: Adolescent; Asthma; Bronchial Provocation Tests; Child; Child, Preschool; Histamine; Humans; Monitor | 1984 |
Recurrent nocturnal asthma after bronchoprovocation with Western Red Cedar sawdust: association with acute increase in non-allergic bronchial responsiveness.
Topics: Adult; Asthma; Bronchial Provocation Tests; Circadian Rhythm; Dust; Histamine; Humans; Male; Middle | 1984 |
[Prostaglandin F2 alpha content of the blood of bronchial asthma patients].
Topics: Acetylcholine; Allergens; Asthma; Dinoprost; Histamine; Humans; Neuraminic Acids; Prostaglandins F | 1983 |
Adenosine antagonism as an alternative mechanism of action of methylxanthines in asthma.
Topics: Adenosine; Adenosine Monophosphate; Airway Resistance; Asthma; Bronchi; Dose-Response Relationship, | 1983 |
Studies on the mechanisms of exercise-induced asthma.
Topics: Adult; Asthma; Asthma, Exercise-Induced; Clemastine; Forced Expiratory Volume; Histamine; Humans; Ma | 1983 |
Hyperreactivity of airways smooth muscle produced in vitro by leukotrienes.
Topics: Acetylcholine; Animals; Asthma; Calcium; Female; Guinea Pigs; Histamine; In Vitro Techniques; Muscle | 1983 |
The response of the airways to nasal stimulation in asthmatics with rhinitis.
Topics: Airway Resistance; Asthma; Histamine; Humans; Nasal Mucosa; Respiratory Function Tests; Rhinitis, Al | 1983 |
Histamine receptors in the bronchi.
Topics: Animals; Asthma; Bronchi; Cimetidine; Histamine; Humans; Receptors, Histamine; Receptors, Histamine | 1983 |
Effect of anticholinergic drugs on the bronchial response to histamine.
Topics: Asthma; Bronchi; Histamine; Humans; Parasympathetic Nervous System; Parasympatholytics; Respiratory | 1983 |
The effect of alpha adrenergic blockade on non-specific airways reactivity and exercise induced asthma.
Topics: Airway Resistance; Asthma; Asthma, Exercise-Induced; Bronchial Provocation Tests; Histamine; Humans; | 1983 |
Effect of airway infections on bronchial reactivity.
Topics: Asthma; Bronchi; Histamine; Humans; Respiratory Tract Infections; Smoking; Virus Diseases | 1983 |
Bronchial hyperreactivity in rhinitis.
Topics: Asthma; Bronchi; Cough; Histamine; Humans; Reference Values; Respiratory Hypersensitivity; Rhinitis | 1983 |
Bronchial challenges with ultrasonic mist, histamine and carbachol: a comparison in 87 asthmatic subjects.
Topics: Adult; Aerosols; Asthma; Bronchial Provocation Tests; Carbachol; Female; Histamine; Humans; Male; Ul | 1983 |
Diurnal variation in exercise-induced asthma.
Topics: Adult; Asthma; Asthma, Exercise-Induced; Circadian Rhythm; Histamine; Humans; Middle Aged; Peak Expi | 1983 |
Some procedures used to assess clinical airway hyperreactivity.
Topics: Asthma; Bronchi; Bronchial Provocation Tests; Histamine; Humans; Methacholine Compounds; Muscle, Smo | 1983 |
Hyper-reactivity--its relationship to histamine receptors.
Topics: Animals; Asthma; Bronchi; Histamine; Humans; Muscle, Smooth; Receptors, Histamine; Respiratory Hyper | 1983 |
Gingival IgE and histamine concentrations in patients with asthma and in patients with periodontitis.
Topics: Adult; Asthma; Chronic Disease; Female; Gingiva; Histamine; Humans; Immunoglobulin E; Male; Middle A | 1984 |
The sympathetic and parasympathetic system in bronchial hyperreactivity. A synthesis.
Topics: Adenine Nucleotides; Asthma; Calcium; Cold Temperature; Desensitization, Immunologic; Dust; Gases; H | 1984 |
The bronchoconstrictor effect of inhaled prostaglandin D2 in normal and asthmatic men.
Topics: Adult; Airway Resistance; Asthma; Bronchi; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug | 1984 |
Modulation of the bronchomotor effects of chemical mediators by prostaglandin F2 alpha in asthmatic subjects.
Topics: Adolescent; Adult; Aerosols; Asthma; Bronchi; Bronchial Provocation Tests; Bronchial Spasm; Dinopros | 1984 |
Rapidly-adapting receptor activity and intratracheal pressure in guinea pigs. II. Action of aspirin and salicylic acid in antagonizing mediators of allergic asthma.
Topics: Animals; Aspirin; Asthma; Bradykinin; Dinoprost; Guinea Pigs; Histamine; Mechanoreceptors; Muscle, S | 1984 |
What is the use of a respiratory function test?
Topics: Adolescent; Aged; Asthma; Bronchial Provocation Tests; Female; Histamine; Humans; Male; Middle Aged; | 1984 |
Desensitization to experimental asthma with 48/80.
Topics: Aerosols; Animals; Asthma; Drug Tolerance; Female; Guinea Pigs; Histamine; Mast Cells; p-Methoxy-N-m | 1984 |
[Effect of histamine on the rosette-forming capacity of peripheral blood T-lymphocytes in patients with pollen-induced bronchial asthma].
Topics: Adult; Asthma; Histamine; Humans; Middle Aged; Pollen; Receptors, Histamine; Rosette Formation; T-Ly | 1983 |
[Clinico-pathogenetic variants of bronchial asthma].
Topics: Adolescent; Adult; Aged; alpha 1-Antitrypsin; Asthma; Dyspnea; Female; Histamine; Humans; Male; Midd | 1983 |
[Effect of histamine on lymphocyte E-rosette formation in patients with a deficiency in the thymus-dependent immunity system].
Topics: Adult; Asthma; Histamine; Humans; Immunologic Deficiency Syndromes; Rhinitis, Allergic, Perennial; R | 1983 |
Changes in free histamine in peripheral circulation following cockroach-antigen challenge in asthmatics.
Topics: Adolescent; Adult; Antigens; Asthma; Bronchial Provocation Tests; Cockroaches; Histamine; Humans; Mi | 1984 |
Histamine dose-response curves in asthma: reproducibility and sensitivity of different indices to assess response.
Topics: Adult; Airway Resistance; Asthma; Bronchi; Bronchial Provocation Tests; Dose-Response Relationship, | 1983 |
Measurement of responsiveness to inhaled histamine using FEV1: comparison of PC20 and threshold.
Topics: Adult; Asthma; Bronchi; Bronchial Provocation Tests; Dose-Response Relationship, Drug; Female; Force | 1983 |
Measurement of responsiveness to inhaled histamine: comparison of FEV1 and SGaw.
Topics: Adult; Airway Resistance; Asthma; Bronchial Provocation Tests; Female; Forced Expiratory Volume; His | 1983 |
[Histamine sensitivity of polymorphonuclear leukocytes of patients with bronchial asthma].
Topics: Adolescent; Adult; Age Factors; Asthma; Child; Child, Preschool; Female; Glucuronidase; Histamine; H | 1983 |
Bronchial responsiveness in children.
Topics: Asthma; Bronchi; Bronchial Provocation Tests; Child; Circadian Rhythm; Exercise Test; Histamine; Hum | 1983 |
Histamine bronchial challenge: effect on regional ventilation and aerosol deposition.
Topics: Adult; Aerosols; Asthma; Bronchial Provocation Tests; Female; Forced Expiratory Volume; Histamine; H | 1983 |
[Plasma histamine levels in allergic diseases. 2. Evaluation of asthmatic attacks and severities].
Topics: Adolescent; Adult; Aged; Asthma; Histamine; Humans; Middle Aged | 1983 |
[Evaluation of the reactivity of the bronchial system in preschool-age children using the histamine provocation test].
Topics: Asthma; Bronchi; Bronchial Provocation Tests; Child, Preschool; Female; Histamine; Humans; Male; Pea | 1983 |
[Effect of biogenic rhythms on plasma histamine level and airway resistance in patients with allergic bronchial asthma].
Topics: Adult; Airway Resistance; Asthma; Circadian Rhythm; Female; Histamine; Humans; Male; Middle Aged; Re | 1983 |
[Cause of bronchial hypersensitivity to histamine and carbachol].
Topics: Airway Resistance; Asthma; Bronchial Provocation Tests; Carbachol; Histamine; Humans | 1983 |
Plasma histamine in asthmatic and control subjects following exercise: influence of circulating basophils and different assay techniques.
Topics: Adult; Asthma; Asthma, Exercise-Induced; Basophils; Forced Expiratory Volume; Histamine; Humans; Hyp | 1983 |
Effect of aerosol fenoterol on the severity of bronchial hyperreactivity in patients with asthma.
Topics: Adult; Aerosols; Asthma; Bronchi; Bronchial Provocation Tests; Dose-Response Relationship, Drug; Eth | 1983 |
[Model for limiting respiratory outflow following a histamine test and physical exercise in asthmatics].
Topics: Adult; Asthma; Female; Histamine; Humans; Male; Physical Exertion; Pulmonary Ventilation | 1983 |
Ascaris-induced bronchoconstriction in primates experimentally infected with Ascaris suum ova.
Topics: Airway Resistance; Albuterol; Allergens; Animals; Ascariasis; Ascaris; Asthma; Atropine; Benzopyrans | 1983 |
Variation with time in bronchial responsiveness to histamine and to specific allergen provocation.
Topics: Allergens; Asthma; Bronchi; Bronchial Provocation Tests; Child; Histamine; Humans; Skin Tests; Time | 1983 |
[Use of histamine inhalation in the treatment of bronchial asthma in children].
Topics: Adolescent; Aerosols; Asthma; Child; Child, Preschool; Histamine; Humans; Respiratory Therapy | 1983 |
[Bronchial hyperreactivity to histamine in young persons re-examined after 4 years].
Topics: Adult; Asthma; Bronchi; Bronchial Provocation Tests; Histamine; Humans; Seasons; Time Factors | 1983 |
[Effect of lidocaine on histamine-induced bronchial spasm].
Topics: Adult; Aged; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Female; Histamine; Histamine Anta | 1983 |
Acute airway changes induced by coughing.
Topics: Airway Resistance; Asthma; Bronchi; Bronchial Provocation Tests; Cough; Histamine; Humans; Respirato | 1984 |
Adenosine-induced bronchoconstriction in asthma. Antagonism by inhaled theophylline.
Topics: Adenosine; Adult; Airway Resistance; Asthma; Bronchial Provocation Tests; Dose-Response Relationship | 1984 |
Neutrophil chemotactic activity and histamine in atopic and nonatopic subjects after exercise-induced asthma.
Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Chemotaxis, Leukocyte; Chromatography, Gel; Fem | 1984 |
Monitoring of maximum expiratory peak flow rates and histamine inhalation tests in the investigation of occupational asthma.
Topics: Asthma; Bronchial Provocation Tests; Histamine; Humans; Male; Middle Aged; Occupational Diseases; Pe | 1984 |
Relationship between bronchial response to respiratory heat exchange and nonspecific airways reactivity in asthmatic patients.
Topics: Adolescent; Adult; Aerosols; Asthma; Bronchi; Bronchial Spasm; Cold Temperature; Female; Forced Expi | 1984 |
[Influence of circulating catecholamines on bronchial sensitivity in vivo].
Topics: Adult; Asthma; Bronchi; Bronchial Provocation Tests; Dose-Response Relationship, Drug; Epinephrine; | 1984 |
Bronchoalveolar lavage. Its safety in subjects with mild asthma.
Topics: Adult; Aminophylline; Asthma; Bronchi; Bronchial Provocation Tests; Bronchoscopy; Evaluation Studies | 1984 |
Cold air challenge of airway hyperreactivity in children: practical application and theoretical aspects.
Topics: Adolescent; Air; Asthma; Bronchi; Bronchial Provocation Tests; Child; Cold Temperature; Female; Hist | 1984 |
The histamine inhalation provocation test and its reproducibility.
Topics: Adolescent; Adult; Asthma; Bronchial Provocation Tests; Female; Forced Expiratory Volume; Histamine; | 1984 |
A comparison of in vivo and in vitro human airway reactivity to histamine.
Topics: Aged; Asthma; Bronchi; Bronchial Provocation Tests; Carbachol; Cimetidine; Dose-Response Relationshi | 1984 |
Immunologic studies in allergen-induced late-phase asthmatic reactions.
Topics: Adolescent; Adult; Allergens; Asthma; Bronchial Provocation Tests; Chemotaxis; Child; Chromatography | 1984 |
[Asthma: the "3 R's" disease (reactivity, reversibility and rhythmicity)].
Topics: Adult; Airway Obstruction; Asthma; Bronchi; Bronchial Provocation Tests; Circadian Rhythm; Female; H | 1984 |
Relationship between atopy and bronchial responsiveness to histamine in a random population.
Topics: Adult; Aerosols; Asthma; Bronchi; Female; Histamine; Humans; Hypersensitivity, Immediate; Male | 1984 |
[Slow reacting substance from human peripheral polymorphonuclear leukocytes by incubation with fresh autologous serum and zymosan. Part 2. SRS release from PMN of bronchial asthmatic patients and regulation by histamine].
Topics: Adolescent; Adult; Asthma; Child; Child, Preschool; Histamine; Humans; Immune Sera; Neutrophils; Rec | 1984 |
[Characterization of slow reacting substance of anaphylaxis in asthmatic sputum].
Topics: Adult; Animals; Arylsulfatases; Asthma; Chromones; Diphenhydramine; Female; Guinea Pigs; Histamine; | 1984 |
Histamine, neutrophil chemotactic factor and circulating basophil levels following exercise in asthmatic and control subjects.
Topics: Adult; Asthma; Asthma, Exercise-Induced; Basophils; Chemotactic Factors; Forced Expiratory Volume; H | 1982 |
Pharmacology of disodium cromoglycate.
Topics: Asthma; Bronchial Spasm; Cromolyn Sodium; Histamine; Humans; Physical Exertion; Reflex; Sulfur Dioxi | 1980 |
Evidence for lipoxygenase pathway involvement in allergic tracheal contraction.
Topics: Animals; Arachidonic Acids; Aspirin; Asthma; Constriction, Pathologic; Guinea Pigs; Histamine; Hyper | 1980 |
[Histamine of peripheral basophils in children with bronchial asthma].
Topics: Adolescent; Asthma; Basophils; Child; Child, Preschool; Cromolyn Sodium; Female; Histamine; Humans; | 1981 |
The bronchial challenge test: a new direction in asthmatic management.
Topics: Asthma; Bronchial Provocation Tests; Histamine; Humans; Methacholine Compounds | 1983 |
Tolerance to sulfur dioxide-induced bronchoconstriction in subjects with asthma.
Topics: Adult; Airway Resistance; Asthma; Bronchi; Bronchial Provocation Tests; Drug Tolerance; Female; Hist | 1983 |
[Recurring croup. New clinical, pathophysiological and etiological aspects].
Topics: Adolescent; Asthma; Bronchial Provocation Tests; Child; Croup; Female; Histamine; Humans; Immunoglob | 1983 |
Potentiation by acetylsalicylic acid of skin weal response to compound 48/80 in ASA-sensitive asthmatics.
Topics: Adult; Aspirin; Asthma; Drug Synergism; Histamine; Humans; Injections, Intradermal; p-Methoxy-N-meth | 1983 |
Unimodal distribution of bronchial responsiveness to inhaled histamine in a random human population.
Topics: Adult; Asthma; Bronchi; Bronchial Provocation Tests; Female; Forced Expiratory Volume; Histamine; Hu | 1983 |
The role of mast cells in asthma.
Topics: Animals; Asthma; Bronchi; Histamine; Histocytochemistry; Humans; Lung; Mast Cells; Rats | 1983 |
Comparison of airway responsiveness to exercise and histamine inhalation in asthmatics.
Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Female; Forced Expiratory Volume; Histamine; Hu | 1983 |
Slope of the dose-response curve: usefulness in assessing bronchial responses to inhaled histamine.
Topics: Adult; Asthma; Bronchi; Bronchial Provocation Tests; Dose-Response Relationship, Drug; Female; Force | 1983 |
Characteristics of airway tone during exercise in patients with asthma.
Topics: Adolescent; Adult; Airway Resistance; Asthma; Bronchi; Female; Functional Residual Capacity; Histami | 1983 |
[The effect of hyposensitization in bronchial asthma of childhood with regard to the histamine reactivity of the bronchial tract].
Topics: Adult; Asthma; Bronchial Provocation Tests; Child; Desensitization, Immunologic; Histamine; Humans; | 1983 |
Histamine inhalation challenge in children: a comparison of two methods.
Topics: Adolescent; Asthma; Bronchial Provocation Tests; Child; Forced Expiratory Volume; Histamine; Humans | 1983 |
Reproducibility of histamine challenge tests in asthmatic children.
Topics: Adolescent; Asthma; Bronchial Provocation Tests; Child; Female; Histamine; Humans; Male; Peak Expira | 1983 |
Short-term and long-term variation in bronchial response to histamine in asthmatic patients.
Topics: Adult; Asthma; Bronchi; Bronchial Provocation Tests; Female; Forced Expiratory Volume; Histamine; Hu | 1983 |
Bronchial responsiveness to histamine: relationship to diurnal variation of peak flow rate, improvement after bronchodilator, and airway calibre.
Topics: Adult; Aged; Albuterol; Asthma; Bronchi; Circadian Rhythm; Female; Forced Expiratory Volume; Histami | 1982 |
Bronchial reactivity following uncomplicated influenza A infection in healthy subjects and in asthmatic patients.
Topics: Adolescent; Adult; Asthma; Bronchi; Female; Histamine; Humans; Influenza A virus; Influenza, Human; | 1980 |
Clinical implications of bronchial hyperreactivity.
Topics: Allergens; Animals; Asthma; Bronchi; Bronchial Provocation Tests; Diagnosis, Differential; Dogs; His | 1980 |
Arterial oxygen changes in asthmatics following histamine.
Topics: Asthma; Histamine; Humans; Oxygen | 1980 |
Bronchial exercise and oral challenge procedures.
Topics: Adult; Aspirin; Asthma; Asthma, Exercise-Induced; Bronchial Provocation Tests; Child; Drug Hypersens | 1981 |
Studies of immunologic and inflammatory factors in saliva in patients with asthma and in patients with periodontitis.
Topics: Adult; Aminopeptidases; Asthma; Calcium; Female; Histamine; Humans; Immunoglobulin E; Male; Middle A | 1981 |
Measurement of airway hyperresponsiveness in man.
Topics: Airway Resistance; Asthma; Bronchial Provocation Tests; Carbachol; Dose-Response Relationship, Drug; | 1982 |
Bronchial responsiveness to histamine or methacholine in asthma: measurement and clinical significance.
Topics: Asthma; Bronchi; Bronchial Provocation Tests; Histamine; Humans; Methacholine Compounds; Peak Expira | 1982 |
Occupational asthma due to soft soldering fluxes containing colophony (rosin, pine resin).
Topics: Allergens; Asthma; Bronchial Provocation Tests; Electronics; Follow-Up Studies; Histamine; Humans; O | 1982 |
Asthma caused by occupational exposure to vanadium compounds.
Topics: Adult; Asthma; Bronchial Provocation Tests; Histamine; Humans; Immunoglobulin E; Male; Middle Aged; | 1982 |
[Histamine and serotonin levels in exercise induced bronchospasm in asthmatics (author's transl)].
Topics: Adolescent; Adult; Asthma; Bronchial Spasm; Female; Histamine; Humans; Male; Physical Exertion; Sero | 1980 |
The multiple facets of histamine research.
Topics: Animals; Asthma; Histamine; Histamine Antagonists; History, 20th Century; Humans; Muscle, Smooth; Pe | 1981 |
Evaluation and expression of bronchial provocation tests.
Topics: Adolescent; Adult; Aged; Antigens; Asthma; Bronchial Provocation Tests; Dose-Response Relationship, | 1981 |
Airway responsiveness to histamine and methacholine: relationship to minimum treatment to control symptoms of asthma.
Topics: Adolescent; Adult; Aged; Albuterol; Asthma; Bronchi; Bronchial Provocation Tests; Female; Forced Exp | 1981 |
Effect of aerosol and oral fenoterol on histamine and methacholine challenge in asthmatic subjects.
Topics: Administration, Oral; Adult; Aerosols; Asthma; Bronchi; Bronchial Provocation Tests; Dose-Response R | 1981 |
A novel double-isotope technique for the enzymatic assay of plasma histamine: application to estimation of mast cell activation assessed by antigen challenge in asthmatics.
Topics: Adult; Antigens; Asthma; Carbon Radioisotopes; Female; Forced Expiratory Volume; Histamine; Humans; | 1982 |
[Bronchial provocation tests by inhalation of non-allergenic agents].
Topics: Aerosols; Asthma; Bronchial Provocation Tests; Dose-Response Relationship, Drug; Histamine; Humans; | 1982 |
Bronchial hyperreactivity. Ghent, 8 November 1980. Introduction.
Topics: Asthma; Bronchi; Histamine; History, 20th Century; Humans; Male; Pilocarpine; Respiratory Hypersensi | 1982 |
Acquired persistent increase in nonspecific bronchial, reactivity associated with isocyanate exposure.
Topics: Adult; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Cyanates; Forced Expiratory Volume; His | 1982 |
Asthma without airway hyperreactivity: fact or artifact?
Topics: Acetylcholine; Asthma; Bronchi; Bronchial Provocation Tests; Forced Expiratory Volume; Histamine; Hu | 1982 |
Bronchial asthma without increased airway reactivity.
Topics: Acetylcholine; Adult; Aerosols; Asthma; Bronchi; Bronchial Provocation Tests; Female; Forced Expirat | 1982 |
Ascaris-induced allergic asthma in the conscious dog: a model for the pharmacologic modulation of immediate type hypersensitivity.
Topics: Animals; Antigens; Ascaris; Asthma; Bronchial Spasm; Disease Models, Animal; Dogs; Female; Histamine | 1982 |
Plasma histamine and catecholamines in stable asthmatic subjects.
Topics: Adult; Asthma; Bronchitis; Chronic Disease; Epinephrine; Female; Forced Expiratory Volume; Histamine | 1982 |
Nonspecific bronchial responsiveness.
Topics: Asthma; Bronchial Provocation Tests; Forced Expiratory Volume; Histamine; Humans; Methacholine Compo | 1982 |
A comparison of histamine, methacholine, and exercise airway reactivity in normal and asthmatic subjects.
Topics: Adult; Airway Resistance; Asthma; Bronchial Provocation Tests; Female; Forced Expiratory Volume; His | 1982 |
[Nasal mucosal hypersensitivity to histamine and acetylcholine in pediatric asthma and nasal allergy (author's transl)].
Topics: Acetylcholine; Adolescent; Asthma; Child; Child, Preschool; Histamine; Humans; Hypersensitivity; Nas | 1982 |
Site of action of inhaled histamine in asymptomatic asthmatic patients.
Topics: Adult; Airway Obstruction; Airway Resistance; Asthma; Bronchial Provocation Tests; Female; Functiona | 1982 |
Allergen-induced increase in bronchial responsiveness to histamine: relationship to the late asthmatic response and change in airway caliber.
Topics: Adolescent; Adult; Airway Resistance; Allergens; Asthma; Bronchi; Bronchial Provocation Tests; Femal | 1982 |
Airway response to salbutamol: effect of regular salbutamol inhalations in normal, atopic, and asthmatic subjects.
Topics: Adolescent; Adult; Airway Resistance; Albuterol; Asthma; Bronchi; Bronchial Provocation Tests; Dose- | 1982 |
Long-term stability of bronchial responsiveness to histamine.
Topics: Adult; Albuterol; Asthma; Beclomethasone; Bronchi; Bronchial Provocation Tests; Female; Forced Expir | 1982 |
Occupational asthma in electronics workers caused by colophony fumes: follow-up of affected workers.
Topics: Adult; Asthma; Bronchial Provocation Tests; Electronics; Female; Follow-Up Studies; Histamine; Human | 1982 |
Correlation of bronchial responsiveness to diluent and to histamine.
Topics: Asthma; Bronchial Provocation Tests; Forced Expiratory Volume; Histamine; Humans; Sodium Chloride | 1982 |
The effect of beclomethasone diproprionate on bronchial hyperreactivity.
Topics: Adolescent; Adult; Aerosols; Aged; Asthma; Beclomethasone; Female; Forced Expiratory Volume; Histami | 1982 |
Bronchial hyperreactivity associated with tracheal gangliosides.
Topics: Animals; Asthma; Bronchial Spasm; Carbohydrate Sequence; Disease Models, Animal; Gangliosides; Glyco | 1982 |
Standardization of inhalation provocation tests. Dose vs concentration of histamine.
Topics: Asthma; Bronchial Provocation Tests; Dose-Response Relationship, Drug; Forced Expiratory Volume; His | 1982 |
Calcium antagonists in experimental asthma.
Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Bronchial Provocation Tests; Calcium Channel Bl | 1982 |
[Pharmacological testing in assessing bronchial function].
Topics: Acetylcholine; Albuterol; Asthma; Bronchi; Bronchial Provocation Tests; Bronchodilator Agents; Child | 1982 |
The perception of breathlessness in asthma.
Topics: Adolescent; Adult; Aged; Airway Obstruction; Asthma; Bronchial Provocation Tests; Female; Forced Exp | 1982 |
Histamine dose-response relationships in normal and asthmatic subjects. The importance of starting airway caliber.
Topics: Adult; Airway Resistance; Albuterol; Asthma; Atropine; Bronchial Provocation Tests; Chlorpheniramine | 1982 |
[Mediators in asthmatic children].
Topics: Airway Obstruction; Airway Resistance; Asthma; Child; Child, Preschool; Histamine; Humans; Infant; I | 1982 |
[Response curve to histamine in the diagnosis and treatment of bronchial asthma].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Asthma; Bronchial Provocation Tests; Bronchodilato | 1982 |
Measurement and clinical significance of bronchial responsiveness to histamine.
Topics: Adolescent; Adult; Asthma; Bronchial Provocation Tests; Female; Forced Expiratory Flow Rates; Histam | 1982 |
[Standard for allergen bronchial provocation tests in asthma and hypersensitivity pneumonitis].
Topics: Acetylcholine; Alveolitis, Extrinsic Allergic; Asthma; Bronchial Provocation Tests; Histamine; Human | 1982 |
Bronchial responsiveness to histamine and allergen in patients with asthma, rhinitis, cough.
Topics: Asthma; Bronchi; Bronchial Provocation Tests; Bronchial Spasm; Cough; Histamine; Humans; Immunoglobu | 1980 |
Repeated histamine inhalation tests in asthmatic patients.
Topics: Adult; Asthma; Bronchial Provocation Tests; Female; Forced Expiratory Volume; Histamine; Humans; Imm | 1981 |
[Venous blood histamine level during aspirin-induced bronchial spasm].
Topics: Adult; Aged; Aspirin; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Female; Forearm; Histami | 1980 |
Exercise-induced asthma and blood histamine.
Topics: Animals; Asthma; Asthma, Exercise-Induced; Histamine; Humans | 1981 |
[Experimental surgical therapy of bronchial asthma. The effect of denervation in dogs (author's transl)].
Topics: Animals; Asthma; Bronchial Provocation Tests; Denervation; Dogs; Histamine; Lung | 1981 |
Bronchodilator activity of a PGE2 analog in animals and in man.
Topics: Acetylcholine; Acute Disease; Animals; Asthma; Biological Assay; Bronchi; Bronchial Spasm; Bronchiti | 1981 |
[Importance of determining histamine and the histaminopexic index in bronchial asthma during imuran therapy].
Topics: Adult; Asthma; Azathioprine; Female; Histamine; Humans; Immunosuppressive Agents; Male; Middle Aged; | 1981 |
Histaminemia after aspirin challenge in aspirin-sensitive asthmatics.
Topics: Adult; Aged; Aspirin; Asthma; Bronchi; Drug Hypersensitivity; Female; Forced Expiratory Volume; Hist | 1981 |
Airway responsiveness to histamine as a test for overall severity of asthma in children.
Topics: Adolescent; Airway Obstruction; Asthma; Bronchospirometry; Child; Female; Forced Expiratory Volume; | 1981 |
[Bronchial reactivity to histamine 5 years after the 1st examination].
Topics: Adult; Asthma; Bronchi; Bronchial Provocation Tests; Follow-Up Studies; Histamine; Humans; Time Fact | 1980 |
[Seasonal variations in the degree of bronchial hypersensitivity in inhaled histamine].
Topics: Adult; Asthma; Bronchi; Bronchial Provocation Tests; Histamine; Humans; Seasons | 1980 |
[Immunological and biochemical indices in children with bronchial asthma in barochambers].
Topics: Adolescent; Asthma; Atmosphere Exposure Chambers; Atmospheric Pressure; Child; Child, Preschool; Com | 1980 |
Arterial plasma histamine after exercise in normal individuals an in patients with exercise-induced asthma.
Topics: Adult; Aging; Arteries; Asthma; Asthma, Exercise-Induced; Forced Expiratory Volume; Histamine; Human | 1981 |
Venous plasma histamine in exercise- and hyperventilation-induced asthma in man.
Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Histamine; Humans; Hyperventilation; Male; Peak | 1981 |
H2 receptor blockade and bronchial hyperreactivity to histamine in asthma.
Topics: Adult; Asthma; Bronchi; Bronchial Provocation Tests; Cimetidine; Double-Blind Method; Female; Guanid | 1981 |
Bronchial reactivity in cystic fibrosis with normal pulmonary function.
Topics: Adolescent; Asthma; Bronchi; Bronchial Provocation Tests; Child; Cystic Fibrosis; Histamine; Humans; | 1981 |
[Blood histamine levels in bronchial asthma].
Topics: Adolescent; Adult; Asthma; Female; Histamine; Humans; Male; Middle Aged | 1981 |
[Principles of diagnosis of bronchial asthma].
Topics: Acetylcholine; Asthma; Bronchi; Bronchial Provocation Tests; Chronic Disease; Diagnosis, Differentia | 1981 |
The effect of verapamil on histamine and methacholine-induced bronchoconstriction.
Topics: Adolescent; Adult; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Female; Forced Expiratory V | 1981 |
Reassessment of electrophysiological and contractile characteristics of sensitized airway smooth muscle.
Topics: Action Potentials; Allergens; Animals; Asthma; Guinea Pigs; Histamine; In Vitro Techniques; Isoprote | 1981 |
Histamine dose-response curves in asthma: relevance of the distinction between PC20 and reactivity in characterising clinical state.
Topics: Adolescent; Adult; Asthma; Bronchi; Bronchial Provocation Tests; Dose-Response Relationship, Drug; F | 1981 |
Modulation of histamine-induced bronchoconstriction with inhaled, oral, and intravenous clemastine in normal and asthmatic subjects.
Topics: Administration, Oral; Adult; Aerosols; Asthma; Bronchial Spasm; Clemastine; Dose-Response Relationsh | 1981 |
[Post-hyperventilation bronchial spasm and bronchial reactivity to inhaled histamine in atopic bronchial asthma].
Topics: Adolescent; Adult; Asthma; Bronchi; Bronchial Provocation Tests; Bronchial Spasm; Female; Histamine; | 1981 |
[Practical value of the study of bronchial reactivity in the diagnosis of bronchial asthma and asthma susceptibility in conscripts].
Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Bronchi; Bronchial Provocation Tests; Disease S | 1981 |
[Skin vascular and bronchoreceptor reactivity study of bronchial asthma].
Topics: Acetylcholine; Asthma; Bronchi; Epinephrine; Histamine; Humans; Receptors, Adrenergic; Skin | 1981 |
Inter-relation of immediate and late asthmatic reactions in childhood.
Topics: Allergens; Animals; Asthma; Bronchial Provocation Tests; Child; Dose-Response Relationship, Immunolo | 1981 |
[Biochemical interactions in bronchial asthma].
Topics: Asthma; Bronchial Spasm; Histamine; Humans; Prostaglandins | 1981 |
Respiratory tract reactions to western red cedar.
Topics: Adult; Asthma; Bronchial Provocation Tests; Dust; Histamine; Humans; Male; Maximal Expiratory Flow R | 1981 |
Effects of ketamine and halothane on normal and asthmatic smooth muscle of the airway in guinea pigs.
Topics: Anaphylaxis; Animals; Asthma; Dose-Response Relationship, Drug; Drug Interactions; Guinea Pigs; Halo | 1980 |
Evaluation of role played by mediators of immediate hypersensitivity in exercise-induced asthma.
Topics: Adult; Airway Resistance; Antigens; Asthma; Asthma, Exercise-Induced; Chemotactic Factors; Cold Temp | 1980 |
Histamine pharmacology in airway smooth muscle from a canine model of asthma.
Topics: Airway Resistance; Anaphylaxis; Animals; Asthma; Dogs; Histamine; In Vitro Techniques; Methylhistami | 1980 |
[Histaminemia in exercise-induced bronchial spasm in patients with bronchial asthma].
Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Exercise Test; Female; Histamine; Humans; Male | 1980 |
Metabolism of 14C-histamine given intrabronchially to asthmatic patients.
Topics: Adult; Asthma; Bronchi; Female; Histamine; Humans; Injections; Injections, Intravenous; Male; Middle | 1980 |
Respiratory allergy to ragweed: correlation of bronchial responses to allergen with bronchial responses to histamine and circulating immunoglobulin E.
Topics: Adult; Allergens; Anthropometry; Asthma; Dose-Response Relationship, Immunologic; Female; Histamine; | 1980 |
Histamine and nocturnal wheezing.
Topics: Asthma; Histamine; Humans | 1980 |
2-decarboxy-2-hydroxymethyl prostaglandin E1 (TR4161), a prostaglandin bronchodilator of low tracheobronchial irritancy.
Topics: Administration, Oral; Aerosols; Alprostadil; Anesthesia; Animals; Asthma; Bronchi; Bronchodilator Ag | 1980 |
[Value of determination of catecholamines, acetylcholine and histamine in the blood serum in nonspecific lung diseases].
Topics: Acetylcholine; Adolescent; Adult; Asthma; Bronchitis; Catecholamines; Chronic Disease; Histamine; Hu | 1980 |
Multiple exercise and histamine challenge in asthmatic patients.
Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Bronchial Provocation Tests; Child; Female; For | 1980 |
[Skin-vascular reactivity study, histamine level in the blood and the serum histaminopexic activity in bronchial asthma].
Topics: Adult; Asthma; Blood Proteins; Epinephrine; Female; Histamine; Humans; Male; Middle Aged; Protein Bi | 1980 |
PGF2 alpha challenge test in asthma and chronic bronchitis.
Topics: Asthma; Bronchial Provocation Tests; Bronchitis; Chronic Disease; Forced Expiratory Volume; Histamin | 1980 |
Alteration of electrophysiological properties of airway smooth muscle from sensitized guinea-pigs.
Topics: Action Potentials; Albumins; Allergens; Animals; Asthma; Guinea Pigs; Histamine; Immunization; Isopr | 1980 |
[Exercise-induced bronchospasm versus the histamine and polymyxin B provocation test in asthma and chronic obstructive bronchitis].
Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Bronchial Provocation Tests; Bronchial Spasm; B | 1980 |
Pulmonary function testing and bronchoprovocation--a simplified office procedure.
Topics: Asthma; Bronchial Spasm; Forced Expiratory Volume; Histamine; Maximal Midexpiratory Flow Rate; Metha | 1980 |
[Bronchial receptor sensitivity to acetylcholine and histamine in bronchial asthma in children].
Topics: Acetylcholine; Asthma; Bronchi; Bronchitis; Child; Histamine; Humans; Pneumonia; Receptors, Drug; Re | 1980 |
Effects of long-term inhaled salbutamol therapy on the provocation of asthma by histamine.
Topics: Adult; Albuterol; Asthma; Bronchial Provocation Tests; Drug Tolerance; Female; Forced Expiratory Vol | 1980 |
Upper and lower airway hyperreactivity in recurrent croup.
Topics: Adolescent; Asthma; Bronchial Provocation Tests; Child; Croup; Female; Histamine; Humans; Laryngitis | 1980 |
Effect of an H1 blocker, chlorpheniramine, on inhalation tests with histamine and allergen in allergic asthma.
Topics: Adult; Allergens; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Chlorpheniramine; Female; Hi | 1980 |
Tonic inspiratory muscle activity as a cause of hyperinflation in histamine-induced asthma.
Topics: Adult; Asthma; Electromyography; Histamine; Humans; Male; Muscles; Respiration | 1980 |
Magnitude and site of airway response to exercise in asthmatics in relation to arterial histamine levels.
Topics: Adult; Airway Obstruction; Airway Resistance; Asthma; Asthma, Exercise-Induced; Bronchospirometry; F | 1980 |
Lung function in young adults who had asthma in childhood.
Topics: Adolescent; Adult; Age Factors; Asthma; Bronchial Provocation Tests; Child; Forced Expiratory Flow R | 1980 |
Comparison of bronchial reactivity to histamine and methacholine in asthmatics.
Topics: Adult; Asthma; Bronchi; Dose-Response Relationship, Drug; Female; Forced Expiratory Volume; Histamin | 1980 |
Airway response to inhaled histamine in asymptomatic long-term marijuana smokers.
Topics: Administration, Intranasal; Adult; Airway Resistance; Asthma; Bronchospirometry; Cannabis; Dose-Resp | 1981 |
Is airway hyperactivity in asthma due to histamine H2-receptor deficiency?
Topics: Animals; Asthma; Bronchi; Cats; Histamine; Humans; Leukocytes; Macaca mulatta; Models, Biological; M | 1980 |
Neural mechanisms in asthma.
Topics: Animals; Asthma; Autonomic Nervous System; Bronchi; Bronchial Spasm; Gagging; Histamine; Humans; Mus | 1981 |
A sensitive and specific radiometric method for the measurement of plasma histamine in normal individuals.
Topics: Adolescent; Adult; Animals; Asthma; Carbon Radioisotopes; Chromatography, Thin Layer; Female; Guinea | 1980 |
Response of human isolated bronchial and lung parenchymal strips to SRS-A and other mediators of asthmatic bronchospasm.
Topics: Acetylcholine; Airway Resistance; Asthma; Bronchi; Bronchial Spasm; Histamine; Humans; In Vitro Tech | 1980 |
Differential effects of histamine on T helper type 2 (TH2) lymphocytes.
Topics: Adolescent; Adult; Asthma; Chloride Channels; Histamine; Humans; In Vitro Techniques; Interleukin-4; | 1995 |
Perception of dyspnoea during acute changes in lung function in patients with either asthma or COPD.
Topics: Aged; Airway Resistance; Asthma; Bronchial Provocation Tests; Dyspnea; Female; Forced Expiratory Vol | 1995 |
Constitutive expression of endothelin in bronchial epithelial cells of patients with symptomatic and asymptomatic asthma and modulation by histamine and interleukin-1.
Topics: Adolescent; Adult; Albuterol; Asthma; Bronchi; Bronchodilator Agents; Bronchoscopy; Cells, Cultured; | 1995 |
Diurnal variation of urinary leukotriene E4 and histamine excretion rates in normal subjects and patients with mild-to-moderate asthma.
Topics: Adult; Asthma; Chromatography, High Pressure Liquid; Circadian Rhythm; Creatinine; Enzyme-Linked Imm | 1995 |
The effect of exercise on basophil histamine release in patients with bronchial asthma.
Topics: Adolescent; Adult; Asthma; Basophils; Exercise; Female; Forced Expiratory Volume; Histamine; Histami | 1994 |
Influence of the menstrual cycle on skin-prick test reactions to histamine, morphine and allergen.
Topics: Adult; Allergens; Asthma; Conjunctivitis, Allergic; Drug Hypersensitivity; Estrogens; Female; Histam | 1995 |
Chronic respiratory symptoms, bronchial responsiveness and dietary sodium and potassium: a population-based study.
Topics: Adolescent; Adult; Age Factors; Aged; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests | 1995 |
Codeine-induced bronchoconstriction and putative bronchial opiate receptors in asthmatic subjects.
Topics: Adolescent; Adult; Asthma; Bronchi; Bronchoconstriction; Bronchoconstrictor Agents; Codeine; Histami | 1994 |
Effects of an antibody to interleukin-5 in a monkey model of asthma.
Topics: Animals; Antibodies, Monoclonal; Ascaris suum; Asthma; Bronchial Hyperreactivity; Bronchoalveolar La | 1995 |
Bronchial hyperreactivity in patients with endobronchial tuberculosis.
Topics: Adolescent; Adult; Aged; Asthma; Bronchial Diseases; Bronchial Hyperreactivity; Bronchial Provocatio | 1995 |
Effects of aerosol administration of a thromboxane receptor antagonist (S-1452) on experimental asthma in guinea pigs.
Topics: Aerosols; Animals; Asthma; Bridged Bicyclo Compounds; Bronchoconstriction; Dose-Response Relationshi | 1994 |
An exercise challenge for epidemiological studies of childhood asthma: validity and repeatability.
Topics: Asthma; Asthma, Exercise-Induced; Bronchial Hyperreactivity; Bronchial Provocation Tests; Child; Epi | 1995 |
Interleukin-11 in respiratory inflammation.
Topics: Animals; Asthma; Bronchial Provocation Tests; Cells, Cultured; Histamine; In Vitro Techniques; Infla | 1995 |
Are asthma-like symptoms due to bronchial or extrathoracic airway dysfunction?
Topics: Adult; Airway Obstruction; Asthma; Bronchial Diseases; Bronchial Hyperreactivity; Bronchial Provocat | 1995 |
Bronchial responsiveness to inhaled histamine in both adults with intrinsic and extrinsic asthma: the importance of prechallenge forced expiratory volume in 1 second.
Topics: Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Chi-Square Distribution; Conf | 1993 |
Plasma and urinary histamine in allergen-induced early and late phase asthmatic responses.
Topics: Adult; Allergens; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Female; Forced Expirator | 1993 |
Characteristics of wheeze during histamine-induced airways obstruction in children with asthma.
Topics: Adolescent; Airway Obstruction; Asthma; Bronchial Provocation Tests; Child; Diagnosis, Computer-Assi | 1995 |
Lung function, airway responsiveness, and respiratory symptoms before and after bronchiolitis.
Topics: Asthma; Breast Feeding; Bronchiolitis; Cohort Studies; Cough; Family; Female; Fetal Blood; Functiona | 1995 |
Antiasthmatic effects of a leukotriene biosynthesis inhibitor (MK-0591) in allergic dogs.
Topics: 5-Lipoxygenase-Activating Proteins; Airway Resistance; Allergens; Animals; Asthma; Bronchoalveolar L | 1995 |
Allergen-induced late asthmatic reactions are associated with elevation of exhaled nitric oxide.
Topics: Adult; Allergens; Asthma; Breath Tests; Bronchial Hyperreactivity; Bronchial Provocation Tests; Forc | 1995 |
A comparison of breathlessness during spontaneous asthma and histamine-induced bronchoconstriction.
Topics: Adolescent; Adult; Aged; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Dyspnea; Female; | 1995 |
Dysfunction of muscarinic M2 receptors after the early allergic reaction: possible contribution to bronchial hyperresponsiveness in allergic guinea-pigs.
Topics: Administration, Inhalation; Allergens; Animals; Asthma; Benzodiazepinones; Bronchial Hyperreactivity | 1995 |
Interleukin-2 and soluble interleukin-2 receptor in bronchoalveolar lavage fluid from patients with bronchial asthma.
Topics: Adult; Asthma; Bronchoalveolar Lavage Fluid; Case-Control Studies; Eosinophils; Female; Forced Expir | 1994 |
Phosphodiesterase inhibitors reduce bronchial hyperreactivity and airway inflammation in unrestrained guinea pigs.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Administration, Inhalation; Analysis of Variance; Animals; Asth | 1995 |
Analysis of tidal expiratory flow pattern in the assessment of histamine-induced bronchoconstriction.
Topics: Adult; Aged; Airway Obstruction; Asthma; Bronchial Provocation Tests; Female; Forced Expiratory Volu | 1995 |
Sympathoadrenal responses to bronchoconstriction in asthma: an invasive and kinetic study of plasma catecholamines.
Topics: Adult; Asthma; Bronchoconstriction; Catecholamines; Epinephrine; Female; Histamine; Humans; Kinetics | 1995 |
Frequency distribution of breath sounds as an indicator of bronchoconstriction during histamine challenge test in asthmatic children.
Topics: Adolescent; Analysis of Variance; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Child; E | 1994 |
Does bronchial hyperresponsiveness precede or follow airway obstruction in asthma or COPD?
Topics: Adult; Analysis of Variance; Asthma; Bronchial Hyperreactivity; Disease Progression; Female; Forced | 1994 |
Pulmonary rehabilitation at moderate altitude: a 1-year follow-up.
Topics: Adult; Altitude; Asthma; Bronchial Provocation Tests; Exercise; Exercise Test; Exercise Tolerance; F | 1994 |
Extrathoracic and intrathoracic airway responsiveness in sinusitis.
Topics: Analysis of Variance; Anti-Bacterial Agents; Anti-Inflammatory Agents; Asthma; Bronchial Hyperreacti | 1995 |
Protein content in bronchoalveolar lavage fluid of patients with asthma and control subjects.
Topics: Adolescent; Adult; Aged; Asthma; Bronchoalveolar Lavage Fluid; Female; Histamine; Humans; Male; Midd | 1995 |
[Comparative analysis of PD25-V50 and PD20-FEV1 as a judgement of bronchial provocation test].
Topics: Adult; Asthma; Bronchial Provocation Tests; Female; Forced Expiratory Volume; Histamine; Humans; Mal | 1994 |
Eosinophil accumulation and activation in antigen-induced late asthmatic response in guinea pigs.
Topics: Airway Resistance; Animals; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoa | 1995 |
[Comparative study of 2 diagnostic tests of aspecific bronchial hyperreactivity].
Topics: Adolescent; Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Child; Exercise T | 1994 |
Five-year changes in airflow obstruction and airway responsiveness in mild to moderate asthma.
Topics: Administration, Inhalation; Adrenal Cortex Hormones; Adult; Aged; Asthma; Female; Forced Expiratory | 1994 |
Properties of T lymphocytes from the airways of patients with asthma. Cytokine production and modulation by histamine.
Topics: Asthma; Bronchi; Cells, Cultured; Clone Cells; Cytokines; Histamine; Humans; T-Lymphocytes | 1995 |
Release of mast-cell-derived mediators after endobronchial adenosine challenge in asthma.
Topics: Adenosine Monophosphate; Adult; Albumins; Asthma; Bronchial Provocation Tests; Bronchoalveolar Lavag | 1995 |
Contribution of a cholinergic reflex mechanism to allergen-induced bronchial hyperreactivity in permanently instrumented, unrestrained guinea-pigs.
Topics: Allergens; Animals; Asthma; Bronchial Hyperreactivity; Bronchoconstriction; Guinea Pigs; Histamine; | 1995 |
Asthma trends.
Topics: Asthma; Bronchial Hyperreactivity; Dose-Response Relationship, Drug; Forced Expiratory Volume; Hista | 1995 |
The effect of TYB-2285 on dual phase bronchoconstriction and airway hypersensitivity in guinea-pigs actively sensitized with ovalbumin.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Calcimycin; Dose-Response Relationship, Drug; Guinea | 1994 |
Phenotypic and functional modulation of normal human alveolar macrophages by histamine.
Topics: Adult; Aged; Asthma; Bronchoalveolar Lavage Fluid; Cells, Cultured; Cycloheximide; Dose-Response Rel | 1994 |
Accumulation of basophils and their chemotactic activity in the airways during natural airway narrowing in asthmatic individuals.
Topics: Adult; Aged; Asthma; Basophils; Bronchi; Bronchoalveolar Lavage Fluid; Bronchodilator Agents; Chemot | 1994 |
Clinical features of adult-relapse asthma in comparison with those of child-onset asthma and adult-onset asthma.
Topics: Administration, Inhalation; Adolescent; Adult; Age of Onset; Asthma; Bronchial Diseases; Female; His | 1994 |
Eosinophil cationic protein (ECP), histamine and tryptase in peripheral blood before and during inhalation challenge with toluene diisocyanate (TDI) in sensitized subjects.
Topics: Administration, Inhalation; Adult; Asthma; Blood Proteins; Chymases; Eosinophil Granule Proteins; Fe | 1994 |
Serum eosinophil cationic protein (ECP) in chronic asthma. Relationship to spirometry, flow-volume curves, PC20, and exacerbations.
Topics: Adult; Asthma; Biomarkers; Blood Proteins; Bronchial Provocation Tests; Chronic Disease; Double-Blin | 1994 |
Effective allergen avoidance at high altitude reduces allergen-induced bronchial hyperresponsiveness.
Topics: Allergens; Altitude; Analysis of Variance; Animals; Asthma; Bronchial Hyperreactivity; Bronchial Pro | 1994 |
Relationships among allergen-induced early and late phase airway obstructions, bronchial hyperreactivity, and inflammation in conscious, unrestrained guinea pigs.
Topics: Airway Obstruction; Allergens; Animals; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tes | 1994 |
Changes in regional ventilation during histamine bronchial challenge in stable asthma.
Topics: Adult; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Female; Forced Expiratory Volume; F | 1994 |
Does refining the histamine bronchoprovocation test improve our ability to diagnose asthma?
Topics: Adolescent; Adult; Asthma; Bronchial Provocation Tests; Histamine; Humans; Middle Aged | 1994 |
Physiologic factors affecting the discriminant ability of provocation doses to histamine.
Topics: Asthma; Discriminant Analysis; Dose-Response Relationship, Drug; Forced Expiratory Volume; Histamine | 1994 |
[A rapid dosimetric method for histamine challenge in asthma diagnosis].
Topics: Adult; Aged; Asthma; Female; Histamine; Humans; Immunologic Tests; Male; Middle Aged; Reproducibilit | 1993 |
Histamine induced changes in breathing pattern may precede bronchoconstriction in selected patients with bronchial asthma.
Topics: Adult; Asthma; Bronchial Provocation Tests; Female; Forced Expiratory Volume; Histamine; Humans; Lun | 1994 |
Serum concentration of soluble interleukin 2 receptors in asthma. Correlation with disease activity.
Topics: Acute Disease; Adrenal Cortex Hormones; Adrenergic beta-Agonists; Adult; Asthma; Biomarkers; Bronchi | 1993 |
Activation by histamine of bronchial epithelial cells from nonasthmatic subjects.
Topics: Adult; Alkaline Phosphatase; Asthma; Bronchi; Cell Adhesion Molecules; Cells, Cultured; Cycloheximid | 1993 |
Markers of eosinophilic inflammation in allergic diseases.
Topics: Asthma; Blood Proteins; Bronchial Provocation Tests; Eosinophil Granule Proteins; Eosinophils; Hista | 1993 |
Airway responsiveness to leukotriene C4 (LTC4), leukotriene E4 (LTE4) and histamine in aspirin-sensitive asthmatic subjects.
Topics: Adolescent; Adult; Aspirin; Asthma; Female; Forced Expiratory Volume; Histamine; Humans; Leukotriene | 1993 |
Relationship of plasma epinephrine and circulating eosinophils to nocturnal asthma.
Topics: Adult; Airway Obstruction; Analysis of Variance; Asthma; Bronchial Provocation Tests; Circadian Rhyt | 1994 |
An exercise challenge protocol for epidemiological studies of asthma in children: comparison with histamine challenge.
Topics: Asthma; Asthma, Exercise-Induced; Bronchial Hyperreactivity; Child; Epidemiologic Methods; Histamine | 1994 |
Follow-up of asthma from childhood to adulthood: influence of potential childhood risk factors on the outcome of pulmonary function and bronchial responsiveness in adulthood.
Topics: Asthma; Bronchi; Bronchial Provocation Tests; Child; Cross-Sectional Studies; Female; Follow-Up Stud | 1994 |
In vivo bronchodilator action of a novel K+ channel opener, KC 399, in the guinea pig.
Topics: Administration, Inhalation; Albuterol; Anesthesia; Animals; Antigens; Asthma; Benzopyrans; Bronchoco | 1994 |
Inflammatory effects of ozone in the upper airways of subjects with asthma.
Topics: Adolescent; Adult; Asthma; Female; Histamine; Humans; Inflammation; Interleukin-8; Leukocyte Count; | 1994 |
Usefulness of repeated measurements of bronchial hyperresponsiveness for the diagnosis of occupational asthma.
Topics: Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Female; Histamine; Humans; Ma | 1994 |
Bronchial responsiveness in children and adolescents: a comparison between previously asthmatic, currently asthmatic, and normal subjects.
Topics: Adolescent; Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Child; Female; Fo | 1994 |
Flow limitation during tidal expiration in symptom-free infants and the subsequent development of asthma.
Topics: Asthma; Bronchial Hyperreactivity; Female; Follow-Up Studies; Functional Residual Capacity; Histamin | 1994 |
Perception scoring of induced bronchoconstriction as an index of awareness of asthma symptoms.
Topics: Adolescent; Adult; Aged; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchocons | 1994 |
Effect of magnitude of airway responsiveness and therapy with inhaled corticosteroid on histamine tachyphylaxis in asthma.
Topics: Administration, Inhalation; Administration, Topical; Adult; Anti-Inflammatory Agents; Asthma; Beclom | 1994 |
Selective type IV phosphodiesterase inhibitors as antiasthmatic agents. The syntheses and biological activities of 3-(cyclopentyloxy)-4-methoxybenzamides and analogues.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Aorta; Asthma; Benzamides; Bronchial Spasm; Eosinophil | 1994 |
Cough variant asthma: a case study with antigen, histamine and methacholine inhalation challenge tests.
Topics: Asthma; Bronchial Provocation Tests; Child; Cough; Dust; Female; Histamine; Humans; Methacholine Chl | 1994 |
Stretch-induced myogenic responses of airways after histamine and carbachol.
Topics: Animals; Asthma; Bronchoconstriction; Carbachol; Histamine; In Vitro Techniques; Male; Muscle, Smoot | 1994 |
Role of histamine in allergen-induced asthmatic reactions, bronchial hyperreactivity and inflammation in unrestrained guinea pigs.
Topics: Allergens; Animals; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchitis; Bron | 1994 |
Spontaneous improvement in bronchial responsiveness and its limit during preadolescence and early adolescence in children with controlled asthma.
Topics: Adolescent; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Child; Dose-Response Rel | 1993 |
Ventilatory pattern during bronchial histamine challenge in asthmatics.
Topics: Adolescent; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Female; Forced Expiratory Volu | 1993 |
Effect of a bronchial provocation test with house-dust mite on blood eosinophilia, eosinophil cationic protein, soluble interleukin-2 receptor, and interleukin-6 in asthmatic children.
Topics: Adolescent; Allergens; Animals; Asthma; Blood Proteins; Bronchial Provocation Tests; Child; Dust; Eo | 1993 |
Plasma histamine and bronchial reactivity in allergic asthma.
Topics: Adolescent; Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Female; Histamine | 1993 |
Risk factors for the persistence of respiratory symptoms in childhood asthma.
Topics: Adult; Asthma; Bronchial Provocation Tests; Child; Cohort Studies; Cough; Female; Follow-Up Studies; | 1993 |
Changes in frequency spectra of breath sounds during histamine challenge test in adult asthmatics and healthy control subjects.
Topics: Adolescent; Adult; Albuterol; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Female; Forc | 1994 |
Effect of induced bronchoconstriction on nasal airflow resistance in patients with asthma.
Topics: Adult; Airway Resistance; Asthma; Bronchoconstriction; Female; Forced Expiratory Volume; Histamine; | 1994 |
Interactive effect of inhaled bradykinin with histamine and PGD2 in bronchial asthma.
Topics: Adult; Aerosols; Aged; Asthma; Bradykinin; Bronchial Hyperreactivity; Dose-Response Relationship, Dr | 1993 |
Heterogeneous effects of histamine on proliferation of lung- and blood-derived T-cell clones from healthy and asthmatic persons.
Topics: Asthma; Blood; Cell Division; Clone Cells; Histamine; Interleukin-2; Lung; Reference Values; T-Lymph | 1993 |
A rapid dosimetric method with controlled tidal breathing for histamine challenge. Repeatability and distribution of bronchial reactivity in a clinical material.
Topics: Adult; Aerosols; Aged; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Chronic Disease; Co | 1993 |
Influence of airway inflammatory changes on airway hyperresponsiveness in asthmatics.
Topics: Adult; Albuterol; Asthma; Beclomethasone; Bronchial Hyperreactivity; Bronchial Provocation Tests; Br | 1993 |
Respiratory resistance and transcutaneous PO2 during histamine provocation in children with bronchial asthma.
Topics: Adolescent; Airway Resistance; Asthma; Blood Gas Monitoring, Transcutaneous; Bronchial Hyperreactivi | 1993 |
Time course of plasma histamine and tryptase following food challenges in children with suspected food allergy.
Topics: Adolescent; Antigens; Asthma; Child; Child, Preschool; Chymases; Female; Food; Food Hypersensitivity | 1993 |
Bronchial epithelial cells of patients with asthma release chemoattractant factors for T lymphocytes.
Topics: Adult; Asthma; Bronchi; Cells, Cultured; Chemotactic Factors; Chemotaxis, Leukocyte; Epithelium; Fem | 1993 |
No increase in plasma histamine during PAF-induced airway obstruction in allergic asthmatics.
Topics: Adult; Airway Resistance; Allergens; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Force | 1993 |
Does baseline airway caliber affect measurements of airway responsiveness to histamine.
Topics: Adult; Asthma; Bronchi; Bronchial Hyperreactivity; Bronchoconstriction; Female; Forced Expiratory Vo | 1993 |
Reduced voluntary drive to breathe in asthmatic subjects.
Topics: Adult; Asthma; Diaphragm; Electric Stimulation; Fatigue; Forced Expiratory Volume; Histamine; Humans | 1993 |
[The histamine-free diet].
Topics: Adolescent; Adult; Amine Oxidase (Copper-Containing); Asthma; Child; Child, Preschool; Dermatitis, A | 1993 |
cAMP-specific phosphodiesterase inhibitor, rolipram, reduces eosinophil infiltration evoked by leukotrienes or by histamine in guinea pig conjunctiva.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Asthma; Conjunctiva; Conjunctivitis; Eosinophilia; Eos | 1993 |
Increased cholinergic antagonism underlies impaired beta-adrenergic response in ovalbumin-sensitized guinea pigs.
Topics: Animals; Asthma; Carbachol; Dinoprostone; Female; Guinea Pigs; Histamine; Immunization; In Vitro Tec | 1993 |
The decrease in severity of asthma in children of parents who smoke since the parents have been exposing them to less cigarette smoke.
Topics: Adolescent; Adult; Analysis of Variance; Asthma; Breath Tests; British Columbia; Bronchial Provocati | 1993 |
Histamine metabolism in nasal polyps.
Topics: Amine Oxidase (Copper-Containing); Aspirin; Asthma; Bronchial Provocation Tests; Histamine; Histamin | 1993 |
Bronchial hyperresponsiveness changes after 5 months of regular procaterol inhalation therapy in asthmatic children.
Topics: Administration, Inhalation; Adolescent; Aerosols; Asthma; Bronchial Hyperreactivity; Bronchial Provo | 1993 |
Bronchial hypersensitivity in asthmatics in long-term symptom-free state.
Topics: Adolescent; Adult; Aged; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Female; His | 1993 |
Bronchial hyperresponsiveness in patients recovering from acute severe asthma.
Topics: Acute Disease; Adolescent; Adult; Aged; Asthma; Bronchi; Bronchial Hyperreactivity; Bronchial Provoc | 1993 |
Airway mucosal inflammation even in patients with newly diagnosed asthma.
Topics: Adult; Asthma; Biopsy; Bronchi; Bronchial Provocation Tests; Bronchitis; Bronchoscopy; Dose-Response | 1993 |
Comparative effects of tetrandrine and berbamine on guineapig airway microvascular leakage induced by platelet-activating factor and other allergic mediators.
Topics: Alkaloids; Animals; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Benzylisoquinolines; Bradykinin | 1993 |
Comparison of the squeeze technique and transcutaneous oxygen tension for measuring the response to bronchial challenge in normal and wheezy infants.
Topics: Asthma; Blood Gas Monitoring, Transcutaneous; Bronchial Provocation Tests; Bronchoconstriction; Fema | 1993 |
Leukotrienes and histamine mediate IgE-dependent contractions of human bronchi: pharmacological evidence obtained with tissues from asthmatic and non-asthmatic subjects.
Topics: Adult; Aged; Asthma; Bronchi; Cyclooxygenase Inhibitors; Female; Histamine; Histamine Antagonists; H | 1993 |
Cellular and biochemical analysis of induced sputum from asthmatic and from healthy subjects.
Topics: Adult; Aged; Albumins; Asthma; Blood Proteins; Cell Count; Chymases; Eosinophil Granule Proteins; Fe | 1993 |
Respiratory symptoms questionnaire for asthma epidemiology: validity and reproducibility.
Topics: Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Female; Histamine; Humans; Ma | 1993 |
[Effect of estradiol on the course of ovalbumin sensitization in guinea pigs].
Topics: Animals; Asthma; Estradiol; Female; Guinea Pigs; Histamine; In Vitro Techniques; Isoproterenol; Lung | 1993 |
Comparison of the effects on bronchial hyperresponsiveness of antiallergic agents and beclomethasone dipropionate in long-term bronchial asthma. A retrospective study.
Topics: Adolescent; Adult; Aged; Asthma; Beclomethasone; Bronchial Hyperreactivity; Bronchial Provocation Te | 1993 |
Assessment of bronchodilator response in children with asthma. Dutch CNSLD Study Group.
Topics: Adolescent; Albuterol; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Child; Forced | 1993 |
Relationship between airway eosinophilia and airway hyperresponsiveness in a late asthmatic model of guinea pigs.
Topics: Animals; Antibodies; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar | 1996 |
House dust mite allergens. A major risk factor for childhood asthma in Australia.
Topics: Administration, Inhalation; Age Factors; Allergens; Animals; Asthma; Australia; Bronchial Hyperreact | 1996 |
Detection of excessive bronchoconstriction in asthma.
Topics: Adult; Aged; Aged, 80 and over; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bron | 1996 |
Peripheral eosinophil counts as a marker of disease activity in intrinsic and extrinsic asthma.
Topics: Adolescent; Adult; Asthma; Child; Child, Preschool; Circadian Rhythm; Eosinophils; Female; Histamine | 1995 |
Investigation of the mechanism of alcohol-induced bronchial asthma.
Topics: Acetaldehyde; Adult; Aged; Albumins; Alcohol Drinking; Asthma; Enzyme-Linked Immunosorbent Assay; Fe | 1996 |
Airway hyper- or hyporeactivity to inhaled spasmogens 24 h after ovalbumin challenge of sensitized guinea-pigs.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine; Administration, Inhal | 1995 |
Evidence for linkage of total serum IgE and bronchial hyperresponsiveness to chromosome 5q: a major regulatory locus important in asthma.
Topics: Adolescent; Adult; Aged; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Child; Chro | 1995 |
Peroxynitrite induces airway hyperresponsiveness in guinea pigs in vitro and in vivo.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstriction; Bronch | 1996 |
Influence of breathing pattern on transcutaneous oxygen and carbon dioxide tension during histamine provocation in children with bronchial asthma.
Topics: Administration, Inhalation; Adolescent; Asthma; Blood Gas Monitoring, Transcutaneous; Bronchial Prov | 1996 |
Regulation of IL-4 and IL-5 secretion by histamine and PGE2.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adolescent; Adult; Asthma; Cells, Cultured; Clone | 1995 |
Increase in non-specific bronchial hyperresponsiveness as an early marker of bronchial response to occupational agents during specific inhalation challenges.
Topics: Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Female; Forced Expiratory Vol | 1996 |
Effects of selective phosphodiesterase inhibitors on platelet-activating factor- and antigen-induced airway hyperreactivity, eosinophil accumulation, and microvascular leakage in guinea pigs.
Topics: Animals; Asthma; Dose-Response Relationship, Drug; Eosinophils; Guinea Pigs; Histamine; Male; Phosph | 1996 |
Immediate and delayed effects of nitrogen dioxide exposure at an ambient level on bronchial responsiveness to histamine in subjects with asthma.
Topics: Adult; Asthma; Blood Proteins; Bronchial Hyperreactivity; Bronchial Provocation Tests; Chymases; Eos | 1996 |
Effects of theophylline and rolipram on antigen-induced airway responses in neonatally immunized rabbits.
Topics: Airway Resistance; Alternaria; Animals; Anti-Inflammatory Agents; Antigens, Fungal; Asthma; Bronchia | 1996 |
[Classification for bronchial asthma from the viewpoint of autonomic nerve function and airway hyperreactivity].
Topics: Asthma; Autonomic Nervous System; Bronchial Hyperreactivity; Dopamine beta-Hydroxylase; Histamine; H | 1995 |
[The effect of bronchial allergen provocation on spontaneous production of histamine releasing factor (HRF) by mononuclear cells in patients with bronchial asthma].
Topics: Adult; Asthma; Biomarkers, Tumor; Bronchial Provocation Tests; Cells, Cultured; Female; Histamine; H | 1996 |
Reactivity to IgE-dependent histamine-releasing activity in asthma or rhinitis.
Topics: Adolescent; Adult; Aged; Allergens; Asthma; Basophils; Biomarkers, Tumor; Bronchial Hyperreactivity; | 1996 |
Relationship between the acid-induced cough response and airway responsiveness and obstruction in children with asthma.
Topics: Acetates; Albuterol; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchodilator | 1996 |
Plasma histamine in patients with tropical disorders and acute asthma who exhibit eosinophilia.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Asthma; Eosinophilia; Female; Histamine; Humans; Male | 1996 |
Assessment of food chemical intolerance in adult asthmatic subjects.
Topics: Administration, Oral; Adult; Asthma; Bronchi; Cross-Over Studies; Diet; Double-Blind Method; Female; | 1996 |
Metaproterenol responsiveness after methacholine- and histamine-induced bronchoconstriction.
Topics: Adrenergic beta-Agonists; Analysis of Variance; Anthropometry; Asthma; Bronchial Provocation Tests; | 1996 |
Disinfectant use as a risk factor for atopic sensitization and symptoms consistent with asthma: an epidemiological study.
Topics: Adult; Agricultural Workers' Diseases; Allergens; Animals; Asthma; Bronchial Hyperreactivity; Bronch | 1996 |
Allergen-induced changes in airway responsiveness are related to baseline airway responsiveness.
Topics: Adolescent; Adult; Allergens; Animals; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Test | 1996 |
Effect of TYB-2285 on antigen-induced airway responses in sheep.
Topics: Animals; Asthma; Bronchi; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchoconstricto | 1996 |
On adjusting measurements of airway responsiveness for lung size and airway caliber.
Topics: Adult; Age Factors; Airway Resistance; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Test | 1996 |
CV6209 inhibits airway wall thickening and airway hyperresponsiveness to histamine induced by intravenous administration of platelet-activating factor in guinea pigs.
Topics: Airway Resistance; Animals; Asthma; Bronchi; Guinea Pigs; Histamine; Histamine Antagonists; Lung; Ma | 1996 |
Allergic bronchial asthma: eosinophil chemotaxis and antihistaminic drug modulation.
Topics: Adolescent; Adult; Asthma; Chemotaxis; Cimetidine; Complement C5a; Diphenhydramine; Eosinophils; Fem | 1996 |
Serum IgE levels, atopy, and asthma in young adults: results from a longitudinal cohort study.
Topics: Adolescent; Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Child; Histamine; | 1996 |
Risk factors for development of asthma in children and adolescents: findings from a longitudinal population study.
Topics: Adolescent; Animals; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Child; Denmark; | 1996 |
Bronchial aspirin challenge causes specific eicosanoid response in aspirin-sensitive asthmatics.
Topics: Adult; Arachidonate 5-Lipoxygenase; Aspirin; Asthma; Blood Proteins; Bronchi; Bronchoalveolar Lavage | 1996 |
Differences in nonspecific bronchial responsiveness between patients with asthma and patients with rhinitis are not explained by type and degree of inhalant allergy.
Topics: Adolescent; Adult; Allergens; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Female | 1997 |
Dysfunctional muscarinic M2 autoreceptors in vagally induced bronchoconstriction of conscious guinea pigs after the early allergic reaction.
Topics: Allergens; Animals; Asthma; Bronchial Hyperreactivity; Bronchoconstriction; Electric Stimulation; Fe | 1996 |
Effect of maturation on allergen-induced airflow obstruction and airway plasma exudation in sensitized guinea pigs.
Topics: Age Factors; Airway Obstruction; Airway Resistance; Allergens; Animals; Asthma; Exudates and Transud | 1997 |
Role of endogenous nitric oxide in airway microvascular leakage induced by inflammatory mediators.
Topics: Aminoquinolines; Animals; Arginine; Asthma; Capillary Permeability; Coloring Agents; Dipeptides; Enz | 1997 |
Mast cell tryptase potentiates histamine-induced contraction in human sensitized bronchus.
Topics: Acetylcholine; Adolescent; Adult; Aged; Asthma; Bronchi; Bronchial Provocation Tests; Bronchoconstri | 1997 |
Anti-allergic effect of an aqueous extract of wu-hu-tang.
Topics: Anaphylatoxins; Animals; Asthma; Cell Degranulation; Disease Models, Animal; Dose-Response Relations | 1997 |
Histamine H2 receptor-mediated airway goblet cell secretion and its modulation by histamine-degrading enzymes.
Topics: Amine Oxidase (Copper-Containing); Animals; Asthma; Cimetidine; Dimaprit; Dose-Response Relationship | 1997 |
Reevaluation of the relationship between within-day bronchial variability and bronchial responsiveness in asthmatic children.
Topics: Allergens; Analysis of Variance; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Chi | 1997 |
Increased levels of protein kinase C in lymphocytes in asthma: possible mechanism of regulation.
Topics: Adolescent; Adult; Aged; Asthma; Carbachol; Cell Fractionation; Cell Membrane; Cromolyn Sodium; Cyto | 1997 |
Assessment of chest wall kinematics by using optical reflectance movement analysis (ORMA) system in asthma.
Topics: Adult; Asthma; Constriction, Pathologic; Evaluation Studies as Topic; Histamine; Humans; Kinetics; R | 1996 |
Voice reactions to histamine inhalation in asthma.
Topics: Administration, Inhalation; Adolescent; Adult; Aged; Asthma; Female; Histamine; Humans; Male; Middle | 1997 |
Blood markers of early and late airway responses to allergen in asthmatic subjects. Relationship with functional findings.
Topics: Adolescent; Adult; Allergens; Asthma; Biomarkers; Blood Proteins; Bronchial Provocation Tests; Chemo | 1997 |
Correlation between bronchoalveolar lavage (BAL) fluid cell lysate histamine content and BAL fluid eosinophil count in atopic and nonatopic asthmatics.
Topics: Adult; Asthma; Bronchoalveolar Lavage Fluid; Cell Count; Eosinophils; Forced Expiratory Volume; Hist | 1997 |
Histamine and tryptase in bronchoalveolar lavage fluid samples from asthmatic children.
Topics: Asthma; Bronchoalveolar Lavage Fluid; Child; Chymases; Histamine; Humans; Mast Cells; Serine Endopep | 1997 |
Adult patients may outgrow their asthma: a 25-year follow-up study.
Topics: Adolescent; Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Cohort Studies; F | 1997 |
Bronchial hyperresponsiveness and cytokines in virus-induced asthma exacerbations.
Topics: Asthma; Bronchial Hyperreactivity; Common Cold; Cytokines; Histamine; Humans; Rhinovirus | 1997 |
The immediate and late allergic response to segmental bronchopulmonary provocation in asthma.
Topics: Adult; Allergens; Animals; Asthma; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Bronch | 1997 |
Enhanced expression of neutral endopeptidase (NEP) in airway epithelium in biopsies from steroid- versus nonsteroid-treated patients with atopic asthma.
Topics: Adrenergic beta-Agonists; Adult; Anti-Asthmatic Agents; Asthma; Beclomethasone; Bronchi; Budesonide; | 1997 |
Airway endothelin levels in asthma: influence of endobronchial allergen challenge and maintenance corticosteroid therapy.
Topics: Adrenal Cortex Hormones; Adult; Allergens; Asthma; Bronchi; Bronchial Provocation Tests; Bronchoalve | 1997 |
Perception of airway narrowing in a general population sample.
Topics: Adult; Allergens; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Female; Forced Exp | 1997 |
Wheezing bronchitis reinvestigated at the age of 10 years.
Topics: Asthma; Bronchitis; Follow-Up Studies; Histamine; Humans; Hypersensitivity, Immediate; Infant; Respi | 1997 |
Occupational asthma caused by triglycidyl isocyanurate (TGIC).
Topics: Adult; Asthma; Bronchial Provocation Tests; Eczema; Eosinophilia; Histamine; Humans; Immunoglobulin | 1997 |
The use of serum eosinophil cationic protein (ECP) in the management of steroid therapy in chronic asthma.
Topics: Administration, Inhalation; Adrenal Cortex Hormones; Adult; Asthma; Biomarkers; Blood Proteins; Bron | 1997 |
Peak flow variation in childhood asthma: relationship to symptoms, atopy, airways obstruction and hyperresponsiveness. Dutch CNSLD Study Group.
Topics: Adolescent; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Child; Female; Forced Ex | 1997 |
Immunotherapy for asthma.
Topics: Asthma; Child; Clinical Trials as Topic; Desensitization, Immunologic; Histamine; Humans; Placebos | 1997 |
The effect of R 15.7/HO, an anti-CD18 antibody, on the late airway response and airway hyperresponsiveness in an allergic rabbit model.
Topics: Alternaria; Animals; Antibodies, Monoclonal; Asthma; Bronchoalveolar Lavage; CD18 Antigens; Disease | 1997 |
Eosinophil cationic protein in induced sputum as a marker of inflammation in asthmatic children.
Topics: Anti-Asthmatic Agents; Asthma; Biomarkers; Blood Proteins; Bronchial Provocation Tests; Bronchodilat | 1997 |
Do sputum eosinophils and ECP relate to the severity of asthma?
Topics: Adolescent; Adult; Aged; Asthma; Blood Cell Count; Blood Proteins; Cell Count; Eosinophil Granule Pr | 1997 |
Predictors of early- and late-phase reactions to bronchial allergen challenge.
Topics: Administration, Inhalation; Adolescent; Adult; Antigens, Dermatophagoides; Asthma; Blood Proteins; B | 1997 |
Comparison of four different measures of bronchial responsiveness in asthmatic children.
Topics: Adolescent; Asthma; Asthma, Exercise-Induced; Bronchial Hyperreactivity; Bronchial Provocation Tests | 1997 |
Direct assessment of small airways reactivity in human subjects.
Topics: Adult; Airway Resistance; Asthma; Bronchi; Bronchial Provocation Tests; Bronchodilator Agents; Bronc | 1998 |
Airway response to formaldehyde inhalation in asthmatic subjects with suspected respiratory formaldehyde sensitization.
Topics: Administration, Inhalation; Adult; Air Pollutants, Occupational; Allergens; Antibodies; Asthma; Bloo | 1998 |
Time course study for airway inflammation and responsiveness by repeated provocation of aeroantigen in guinea pigs.
Topics: Airway Obstruction; Airway Resistance; Animals; Antigens; Asthma; Bridged Bicyclo Compounds; Bronchi | 1997 |
The combined influence of immunotherapy and mite allergen reduction on bronchial hyperresponsiveness in mite-sensitive asthmatic children.
Topics: Adolescent; Animals; Asthma; Bedding and Linens; Bronchial Hyperreactivity; Bronchial Provocation Te | 1998 |
Platelet activating factor revisited.
Topics: Asthma; Basophils; Granulocyte-Macrophage Colony-Stimulating Factor; Histamine; Humans; Leukotrienes | 1997 |
Exhaled nitric oxide correlates with airway hyperresponsiveness in steroid-naive patients with mild asthma.
Topics: Adrenergic beta-Agonists; Adult; Airway Obstruction; Anti-Asthmatic Agents; Anti-Inflammatory Agents | 1998 |
Is tyrosine kinase activation involved in basophil histamine release in asthma due to western red cedar?
Topics: Allergens; Antibodies, Anti-Idiotypic; Asthma; Basophils; Cinnamates; Environmental Exposure; Enzyme | 1998 |
Longitudinal determinants of bronchial responsiveness to inhaled histamine.
Topics: Administration, Inhalation; Adolescent; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tes | 1998 |
Histamine affects interleukin-4, interleukin-5, and interferon-gamma production by human T cell clones from the airways and blood.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Albuterol; Asthma; Bronchoalveolar Lavage Fluid; Clone | 1998 |
Correlation between alcohol-induced asthma and acetaldehyde dehydrogenase-2 genotype.
Topics: Acetaldehyde; Adult; Aged; Aldehyde Oxidoreductases; Allergens; Asthma; Ethanol; Female; Genotype; H | 1998 |
CD11b and L-selectin expression on eosinophils and neutrophils in blood and induced sputum of patients with asthma compared with normal subjects.
Topics: Adult; Asthma; Eosinophils; Female; Flow Cytometry; Fluorescent Antibody Technique; Forced Expirator | 1998 |
Inhaled procaterol inhibits histamine-induced airflow obstruction and microvascular leakage in guinea-pig airways with allergic inflammation.
Topics: Administration, Inhalation; Adrenergic beta-Agonists; Airway Resistance; Animals; Asthma; Bronchi; C | 1998 |
Identification of IL-16 as the lymphocyte chemotactic activity in the bronchoalveolar lavage fluid of histamine-challenged asthmatic patients.
Topics: Adult; Asthma; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Chemokine CCL3; Chemokine | 1998 |
Different roles of histamine and leukotriene C4 in the airways between patients with atopic and nonatopic asthma.
Topics: Adult; Aging; Asthma; Blood Cells; Bronchi; Bronchoalveolar Lavage Fluid; Calcimycin; Female; Histam | 1998 |
Amplitude variation in static-charge-sensitive bed signal increased in obstructive airways disease.
Topics: Administration, Inhalation; Adult; Asthma; Ballistocardiography; Bronchoconstriction; Female; Forced | 1998 |
Dual action of iNOS-derived nitric oxide in allergen-induced airway hyperreactivity in conscious, unrestrained guinea pigs.
Topics: Acute Disease; Adjuvants, Immunologic; Allergens; Animals; Asthma; Bronchial Hyperreactivity; Bronch | 1998 |
Linkage of chromosome 5q and 11q gene markers to asthma-associated quantitative traits in Australian children.
Topics: Adolescent; Adult; Animals; Asthma; Australia; Bronchial Provocation Tests; Bronchoconstrictor Agent | 1998 |
Prevalence of occupational asthma among automobile and furniture painters in the center of Eskisehir (Turkey): the effects of atopy and smoking habits on occupational asthma.
Topics: Adolescent; Adult; Aged; Asthma; Bronchial Provocation Tests; Histamine; Humans; Hypersensitivity, I | 1998 |
Involvement of tachykinin NK1 receptor in the development of allergen-induced airway hyperreactivity and airway inflammation in conscious, unrestrained guinea pigs.
Topics: Allergens; Animals; Asthma; Bronchi; Bronchial Hyperreactivity; Bronchial Provocation Tests; Broncho | 1999 |
Exhaled nitric oxide measurements in a population sample of young adults.
Topics: Adult; Asthma; Breath Tests; Bronchial Hyperreactivity; Bronchial Provocation Tests; Child; Dose-Res | 1999 |
The late asthmatic response is associated with baseline allergen-specific proliferative responsiveness of peripheral T lymphocytes in vitro and serum interleukin-5.
Topics: Adolescent; Adult; Allergens; Animals; Antigens, Dermatophagoides; Asthma; Bronchial Provocation Tes | 1999 |
Exhaled nitric oxide; relationship to clinicophysiological markers of asthma severity.
Topics: Adolescent; Adult; Asthma; Biomarkers; Breath Tests; Bronchial Hyperreactivity; Female; Forced Expir | 1998 |
Inflammatory mediators in bronchoalveolar lavage samples from children with and without asthma.
Topics: Adolescent; Asthma; Bronchoalveolar Lavage Fluid; Child; Child, Preschool; Chymases; Eosinophils; Fe | 1999 |
Cough as the ambiguous indicator of airway obstruction in asthma.
Topics: Adolescent; Airway Obstruction; Asthma; Bronchial Provocation Tests; Child; Cough; Dyspnea; Exercise | 1999 |
Inhibitory effects of azelastine hydrochloride in alcohol-induced asthma.
Topics: Acetaldehyde; Adult; Aged; Asthma; Bronchoconstrictor Agents; Bronchodilator Agents; Ethanol; Female | 1999 |
Bronchial allergen challenge in subjects with low levels of allergic sensitization to indoor allergens.
Topics: Adult; Animals; Antigens, Dermatophagoides; Asthma; Bronchial Provocation Tests; Cats; Female; Glyco | 1999 |
Allergen-induced accumulation of eosinophils and lymphocytes in skin chambers is associated with increased levels of interleukin-4 and sVCAM-1.
Topics: Adult; Allergens; alpha-Macroglobulins; Asthma; Blister; Eosinophils; Female; Flow Cytometry; Histam | 1999 |
Measuring breathlessness during histamine challenge: a simple standardized procedure in asthmatic patients.
Topics: Adult; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Dyspnea; Female; Forced Expiratory | 1999 |
Pretreatment intravenous lidocaine for intubation of the asthmatic patient: more data are needed.
Topics: Anesthetics, Local; Asthma; Bronchoconstriction; Histamine; Humans; Intubation, Intratracheal; Lidoc | 1999 |
Histamine provocation in young, awake children with bronchial asthma, using a fall in oxygenation as the only indicator of a bronchial reaction.
Topics: Age Factors; Asthma; Blood Gas Monitoring, Transcutaneous; Carbon Dioxide; Child; Child, Preschool; | 1999 |
Human isolated airway contraction: interaction between air pollutants and passive sensitization.
Topics: Acrolein; Adult; Air Pollutants; Airway Resistance; Asthma; Bronchi; Bronchial Hyperreactivity; Bron | 1999 |
Role of tachykinin NK2-receptor activation in the allergen-induced late asthmatic reaction, airway hyperreactivity and airway inflammatory cell influx in conscious, unrestrained guinea-pigs.
Topics: Allergens; Animals; Asthma; Benzamides; Bronchial Hyperreactivity; Bronchoconstriction; Female; Guin | 1999 |
CD69 surface expression on human lung eosinophils after segmental allergen provocation.
Topics: Adult; Allergens; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Asthma; Bronchial Provocati | 1999 |
Effects of a new antiallergic agent, VUF-K-8788, on experimental asthmatic reactions in guinea pigs.
Topics: Airway Resistance; Anaphylaxis; Animals; Anti-Allergic Agents; Anti-Asthmatic Agents; Antigens; Asth | 1999 |
Both inhaled histamine and hypertonic saline increase airway reactivity in non-sensitised rabbits.
Topics: Aerosols; Animals; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstricti | 1999 |
Agreement between spirometry and tracheal auscultation in assessing bronchial responsiveness in asthmatic children.
Topics: Adolescent; Asthma; Auscultation; Child; Dose-Response Relationship, Drug; Female; Forced Expiratory | 1999 |
Chest wall hyperinflation during acute bronchoconstriction in asthma.
Topics: Abdominal Muscles; Adult; Airway Resistance; Asthma; Bronchoconstriction; Forced Expiratory Volume; | 1999 |
Prevention of severe premenstrual asthma attacks by leukotriene receptor antagonist.
Topics: Adolescent; Adult; Anti-Asthmatic Agents; Asthma; Chromones; Cytokines; Female; Histamine; Humans; L | 1999 |
Experimental rhinovirus 16 infection causes variable airway obstruction in subjects with atopic asthma.
Topics: Adolescent; Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Common Cold; Fema | 1999 |
Passive sensitization of human airways increases responsiveness to leukotriene C4.
Topics: Adult; Aged; Allergens; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Carbachol; Dose-Re | 1999 |
Correlation between respiratory function and airway inflammation in asthma.
Topics: Adult; Asthma; Eosinophils; Female; Histamine; Humans; Inflammation; Male; Respiration; Respiratory | 1999 |
Cut-off points defining normal and asthmatic bronchial reactivity to exercise and inhalation challenges in children and young adults.
Topics: Administration, Inhalation; Adolescent; Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocat | 1999 |
Expression of interleukin-16 by human epithelial cells. Inhibition by dexamethasone.
Topics: Adult; Aged; Asthma; Bronchi; Bronchiectasis; Bronchiolitis; Cell Line; Cycloheximide; Dactinomycin; | 1999 |
Perception of bronchoconstriction in asthma patients measured during histamine challenge test.
Topics: Adult; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Bronchoconstrictor Agents; Female; | 1999 |
Does this dog have asthma?
Topics: Alprostadil; Anesthesia, Inhalation; Animals; Asthma; Bronchial Spasm; Bronchodilator Agents; Dogs; | 1999 |
Bronchoprotective effects of atrial natriuretic peptide against propranolol-induced bronchoconstriction after allergic reaction in guinea pigs.
Topics: Allergens; Animals; Asthma; Atrial Natriuretic Factor; Bronchoconstriction; Bronchodilator Agents; D | 2000 |
The effect of dopamine on the rapidly adapting receptors in the dog lung.
Topics: Adrenergic beta-Agonists; Airway Resistance; Animals; Asthma; Chemoreceptor Cells; Disease Models, A | 2000 |
[Membrane-receptor disorders in adrenergic and histaminergic systems under peroxide exposure in bronchial asthma patients].
Topics: Adrenergic Agonists; Adrenergic beta-Antagonists; Asthma; Cimetidine; Diphenhydramine; Epinephrine; | 2000 |
Comparative study of platelet histamine and serotonin with their corresponding plasma oxidases in asthmatics with normals.
Topics: Adult; Amine Oxidase (Copper-Containing); Asthma; Blood Platelets; Female; Histamine; Humans; India; | 1999 |
Expression of CD35 (CR1) and CD11b (CR3) on circulating neutrophils and eosinophils from allergic asthmatic children.
Topics: Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Cells, Cultured; Child; Eosinophils; | 1993 |
Importance of house dust mite and Alternaria allergens in childhood asthma: an epidemiological study in two climatic regions of Australia.
Topics: Allergens; Alternaria; Animals; Antigens, Dermatophagoides; Antigens, Fungal; Asthma; Australia; Bro | 1993 |
[Biochemical markers of inflammation and bronchial obstruction].
Topics: Asthma; Biomarkers; Bronchitis; Bronchoalveolar Lavage Fluid; Histamine; Humans; Lung Diseases, Obst | 2000 |
Histamine N-methyltransferase pharmacogenetics: association of a common functional polymorphism with asthma.
Topics: Adult; Aged; Alleles; Asthma; Black People; Female; Gene Frequency; Genetic Predisposition to Diseas | 2000 |
Longitudinal changes in bronchial responsiveness associated with swine confinement dust exposure.
Topics: Adult; Agricultural Workers' Diseases; Animal Husbandry; Animals; Asthma; Bronchial Hyperreactivity; | 2000 |
Determination of histamine, 1-methylhistamine and N-methylhistamine by capillary electrophoresis with micelles.
Topics: Adult; Asthma; Electrophoresis, Capillary; Female; Food; Histamine; Humans; Male; Methylhistamines; | 2000 |
Chronic cough.
Topics: Asthma; Bronchial Diseases; Cough; Diagnosis, Differential; Eosinophilia; Histamine; Humans; Predict | 1999 |
Effects of inhaled low molecular weight heparin on airway allergic inflammation in aerosol-ovalbumin-sensitized guinea pigs.
Topics: Administration, Inhalation; Aerosols; Animals; Anti-Allergic Agents; Asthma; Blood Proteins; Broncho | 2000 |
Bronchial sensitivity to histamine in former asthmatics: redevelopment of symptoms during a year of followup.
Topics: Adolescent; Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Female; Follow-Up | 2000 |
Prednisolone hastens recovery from histamine-induced bronchospasm in asthmatics.
Topics: Administration, Oral; Adult; Asthma; Bronchial Spasm; Female; Forced Expiratory Volume; Glucocortico | 2000 |
Atopy influences exhaled nitric oxide levels in adult asthmatics.
Topics: Administration, Inhalation; Adult; Allergens; Analysis of Variance; Asthma; Bronchial Hyperreactivit | 2000 |
Magnesium levels in plasma and erythrocytes before and after histamine challenge.
Topics: Adult; Analysis of Variance; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Erythro | 2000 |
Allergic asthma induced in rhesus monkeys by house dust mite (Dermatophagoides farinae).
Topics: Animals; Antigens, Dermatophagoides; Asthma; Bronchi; Bronchial Provocation Tests; Bronchoalveolar L | 2001 |
Predictive markers of asthma exacerbation during stepwise dose reduction of inhaled corticosteroids.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Asthma; Breath Tests; Bronchial Hyperreactivity; B | 2001 |
Predictive markers of asthma exacerbation during stepwise dose reduction of inhaled corticosteroids.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Asthma; Breath Tests; Bronchial Hyperreactivity; B | 2001 |
Predictive markers of asthma exacerbation during stepwise dose reduction of inhaled corticosteroids.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Asthma; Breath Tests; Bronchial Hyperreactivity; B | 2001 |
Predictive markers of asthma exacerbation during stepwise dose reduction of inhaled corticosteroids.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Asthma; Breath Tests; Bronchial Hyperreactivity; B | 2001 |
Role of chemical mediators in airway hyperresponsiveness in an asthmatic model.
Topics: Airway Resistance; Animals; Asthma; Bronchial Hyperreactivity; Disease Models, Animal; Dose-Response | 2001 |
Chronic cough in children: bronchoalveolar lavage findings.
Topics: Asthma; Blood Proteins; Bronchoalveolar Lavage Fluid; Child; Child, Preschool; Chronic Disease; Coug | 2000 |
Histamine challenges discriminate between symptomatic and asymptomatic children. MAS-Study Group. Multicentre Allergy Study.
Topics: Allergens; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Child; Cohort Studies; Di | 2001 |
Eosinophils and airway hyper-responsiveness.
Topics: Antibodies, Monoclonal; Asthma; Bronchial Provocation Tests; Eosinophilia; Histamine; Humans; Interl | 2001 |
Calcium sensors as new therapeutic targets for airway hyperresponsiveness and asthma.
Topics: Acetylcholine; Animals; Asthma; Bradykinin; Calcium; Calcium Channels; Carrier Proteins; Epithelium; | 2001 |
Role of nitric oxide and superoxide in allergen-induced airway hyperreactivity after the late asthmatic reaction in guinea-pigs.
Topics: Allergens; Animals; Asthma; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Guinea Pigs; Hista | 2001 |
Nerve growth factor increases airway responses and decreases levels of exhaled nitric oxide during histamine challenge in an in vivo guinea-pig model.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Bronchoconstriction; Guinea Pigs; Histamine; Injections, | 2001 |
Late phase responses after nasal challenges with allergen and histamine in asthmatic children with perennial nasal allergy.
Topics: Adolescent; Allergens; Asthma; Child; Female; Histamine; Humans; Male; Nasal Provocation Tests; Repr | 2001 |
Bronchodilatory and anti-inflammatory properties of inhaled selective phosphodiesterase inhibitors in a guinea pig model of allergic asthma.
Topics: Administration, Inhalation; Allergens; Animals; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Bro | 2001 |
Enhanced expression of mucin genes in a guinea pig model of allergic asthma.
Topics: Amino Acid Sequence; Animals; Antineoplastic Agents; Asthma; Base Sequence; Bronchial Hyperreactivit | 2001 |
The relationship between interleukin-8 and airway hyperresponsiveness in guinea pigs.
Topics: Animals; Asthma; Bronchi; Bronchial Hyperreactivity; Guinea Pigs; Histamine; Interleukin-8; Lung; Ma | 1999 |
Relationship between intracellular calcium and airway reactivity in guinea pigs.
Topics: Administration, Inhalation; Animals; Asthma; Calcium; Calcium-Transporting ATPases; Disease Models, | 2001 |
Complement factors C3a and C5a are increased in bronchoalveolar lavage fluid after segmental allergen provocation in subjects with asthma.
Topics: Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; | 2001 |
Perception of bronchoconstriction in elderly asthmatics.
Topics: Adult; Age of Onset; Aged; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Case-Control St | 2001 |
[The changes of protein kinase C activity in peripheral blood lymphocytes in asthmatic patients].
Topics: Adult; Asthma; Cells, Cultured; Female; Histamine; Humans; Leukocytes, Mononuclear; Lung; Lymphocyte | 1999 |
[The role of dexamethasone on airway wall remodeling].
Topics: Administration, Inhalation; Animals; Anti-Inflammatory Agents; Asthma; Cells, Cultured; Dexamethason | 2001 |
Virus-induced asthma attacks.
Topics: Adult; Asthma; Bronchodilator Agents; Cholinergic Antagonists; Coronavirus Infections; Female; Gluco | 2002 |
Effects of cyclosporin A by aerosol on airway hyperresponsiveness and inflammation in guinea pigs.
Topics: Acetylcholine; Aerosols; Animals; Anti-Asthmatic Agents; Asthma; Bronchoalveolar Lavage; Cyclosporin | 2002 |
Inhibition of beta-estradiol on trachea smooth muscle contraction in vitro and in vivo.
Topics: Acetylcholine; Animals; Asthma; Estradiol; Guinea Pigs; Histamine; In Vitro Techniques; Male; Muscle | 2002 |
N-Acetyltransferase genotypes as modifiers of diisocyanate exposure-associated asthma risk.
Topics: Acetylation; Adult; Arylamine N-Acetyltransferase; Asthma; Case-Control Studies; DNA; Female; Geneti | 2002 |
Histamine and serotonin stimulate eotaxin production by a human lung fibroblast cell line.
Topics: Asthma; Cell Line; Chemokine CCL11; Chemokines, CC; Chemotaxis, Leukocyte; Fibroblasts; Gene Express | 2002 |
Further studies on the mechanism of human histamine-induced asthma: the effect of an aerosolized H1 receptor antagonist (diphenhydramine).
Topics: Asthma; Bronchi; Bronchial Spasm; Diphenhydramine; Histamine; Histamine H1 Antagonists; Humans | 1977 |
Neurohumoral interactions in airways.
Topics: Airway Resistance; Animals; Asthma; Cyclic AMP; Cyclic GMP; Dogs; Histamine; In Vitro Techniques; Lu | 1977 |
Action of atropine on histamine-induced bronchoconstriction in asthmatic children. A pharmacocapnographic study.
Topics: Adolescent; Aerosols; Airway Resistance; Asthma; Atropine; Bronchi; Carbon Dioxide; Child; Child, Pr | 1977 |
Bronchial reactivity in asthma to inhaled histamine during treatment with ketotifen.
Topics: Adult; Asthma; Bronchi; Female; Histamine; Histamine H1 Antagonists; Humans; Male; Middle Aged; Pipe | 1979 |
Granulocyte response in vitro to isoproterenol, histamine, and prostaglandin E1, during treatment with beta-adrenergic aerosols in asthma.
Topics: Adolescent; Adrenergic beta-Agonists; Adult; Aerosols; Albuterol; Asthma; Cyclic AMP; Glucuronidase; | 1979 |
Preventive effect of ketotifen, a new antiallergic agent, on histamine-induced bronchoconstriction in asthmatics.
Topics: Adolescent; Adult; Asthma; Constriction, Pathologic; Female; Forced Expiratory Volume; Histamine; Hi | 1979 |
[Effect of a histamine aerosol in 20 subjects with histamine hyperreactivity. Application to a study of the protective properties of pipoxizine].
Topics: Aerosols; Airway Resistance; Aminoacridines; Asthma; Forced Expiratory Volume; Histamine; Histamine | 1978 |
Histamine release during antigen inhalation in experimental asthma in dogs.
Topics: Aerosols; Airway Resistance; Animals; Antigens; Ascaris; Asthma; Blood Pressure; Cattle; Dogs; Heart | 1975 |
[Use of immunosorbents for determining antibodies to histaglobulin].
Topics: Antibodies; Asthma; Bronchitis; Child; Drug Combinations; Eczema; gamma-Globulins; Histamine; Humans | 1975 |
[Bronchial reactivity in asthma. Immunopharmacological data].
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aged; alpha 1-Antitrypsin Deficiency; Antibod | 1977 |
[Clinical experiences with histamine-azoprotein and serotonine-azo-protein in the therapy of allergic diseases (author's transl)].
Topics: Asthma; Azo Compounds; Dermatitis; Dermatitis, Atopic; Dermatitis, Contact; gamma-Globulins; Haptens | 1977 |
[Release of histamine from leukocytes. A comparison between allergic and intrinsic asthma and normal persons (author's transl)].
Topics: Adult; Asthma; Female; Histamine; Histamine Release; Humans; Leukocytes; Male; Middle Aged | 1978 |
Histamine release in exercise-induced asthma.
Topics: Asthma; Histamine; Histamine Release; Humans; Physical Exertion | 1978 |
[Theoretical bases for possible clinical use of histamine in the light of new concepts in regard to H2 receptor and cyclic AMP system].
Topics: Animals; Asthma; Child, Preschool; Cyclic AMP; Drug Combinations; gamma-Globulins; Histamine; Histam | 1978 |
[Histamine levels in blood of patients with allergic bronchial asthma (author's transl)].
Topics: Adult; Asthma; Bronchi; Bronchitis; Chronic Disease; Female; Histamine; Histamine Release; Humans; M | 1979 |
Changes in histamine and cyclic nucleotide levels after bronchoprovocation in patients with extrinsic asthma.
Topics: 1-Methyl-3-isobutylxanthine; Adolescent; Adult; Allergens; Asthma; Bronchial Spasm; Cyclic AMP; Cycl | 1978 |
Mediator release during allergen-induced bronchoconstriction in asthmatic subjects.
Topics: Allergens; Animals; Asthma; Bronchi; Cats; Complement Activation; Complement C3; Complement C4; Comp | 1979 |
Mediators of immediate-type hypersensitivity in sputum from patients with chronic bronchitis and asthma.
Topics: Adult; Aged; Asthma; Bronchitis; Chronic Disease; Eosinophilia; Histamine; Humans; Hypersensitivity, | 1977 |
Comparisons of the effects of fenoterol on PCA and histamine skin test in rats.
Topics: Aminophylline; Animals; Asthma; Cromolyn Sodium; Diphenhydramine; Ethanolamines; Fenoterol; Forced E | 1978 |
[Relationship of blood histamine and histaminase activity in chronic nonspecific lung diseases].
Topics: Adult; Aged; Amine Oxidase (Copper-Containing); Asthma; Bronchial Spasm; Chronic Disease; Enzyme Act | 1978 |
Airway responses to histamine and methocholine in Ascaris suum-allergic rhesus monkeys.
Topics: Aerosols; Animals; Antigens; Ascaris; Asthma; Bronchial Spasm; Functional Residual Capacity; Haplorh | 1978 |
Blood histamine levels after exercise testing.
Topics: Asthma; Asthma, Exercise-Induced; Basophils; Blood Cell Count; Cromolyn Sodium; Forced Expiratory Vo | 1979 |
Protective effect of drugs on histamine-induced asthma.
Topics: Albuterol; Ascorbic Acid; Asthma; Atropine; Choline; Cromolyn Sodium; Female; Histamine; Humans; Ipr | 1977 |
[Exercise-induced-asthma (author's transl)].
Topics: Adolescent; Airway Resistance; Asthma; Bronchi; Hexoprenaline; Histamine; Humans; Ipratropium; Muscl | 1977 |
Use of a new simple device, the airflometer, in detecting changes in airways obstuction.
Topics: Adolescent; Adult; Aged; Airway Obstruction; Asthma; Evaluation Studies as Topic; Female; Histamine; | 1977 |
Bronchial hyperreactivity to histamine and methacholine in asthmatic children after inhalation of SCH 1000 and chlorpheniramine maleate.
Topics: Adolescent; Aerosols; Asthma; Atropine Derivatives; Child; Chlorpheniramine; Dose-Response Relations | 1978 |
Effect of Sch1000 in allergen-induced asthma.
Topics: Administration, Intranasal; Allergens; Asthma; Atropine Derivatives; Bronchi; Constriction, Patholog | 1978 |
The effects of ipratropium bromide on the histamine inhalation challenge in asthmatic and bronchitic patients.
Topics: Asthma; Atropine Derivatives; Bronchitis; Drug Evaluation; Histamine; Humans; Ipratropium; Peak Expi | 1979 |
Metabolism, production, and release of hormones and mediators in the lung.
Topics: Adenine Nucleotides; Angiotensin II; Animals; Asthma; Bradykinin; Chemotaxis; Histamine; Hormones; H | 1975 |
Pharmacodynamic study of the capillaries of normal and allergic (atopic) subjects.
Topics: Adolescent; Adult; Animals; Asthma; Capillary Resistance; Catecholamines; Child; Cyclic AMP; Dermati | 1975 |
[Cyclic AMP and asthma].
Topics: Acetylcholine; Antigen-Antibody Reactions; Asthma; Bradykinin; Bronchial Spasm; Cyclic AMP; Histamin | 1975 |
Correlation between increased bronchial responsiveness to histamine and diminished plasma cyclic adenosine monophosphate response after epinephrine in asthmatic children. Diminished plasma cyclic adenosine monophosphate response after epinephrine in moder
Topics: Adolescent; Asthma; Child; Cyclic AMP; Epinephrine; Female; Histamine; Humans; Male; Receptors, Adre | 1977 |
Decreased H2 histamine response of granulocytes of asthmatic patients.
Topics: Adult; Asthma; Bronchitis; Chlorpheniramine; Cyclic AMP; Dose-Response Relationship, Drug; Female; G | 1977 |
The in vitro effect of toluene diisocyanate on lymphocyte cyclic adenosine monophosphate production by isoproterenol, prostaglandin, and histamine: a possible mode of action.
Topics: Asthma; Cyanates; Cyclic AMP; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Drug Interaction | 1977 |
Changes of airway smooth muscle in experimental asthma.
Topics: Animals; Asthma; Carbachol; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Male; Muscle C | 1978 |
Mediators and the mechanism of their release.
Topics: Animals; Asthma; Basophils; Blood Platelets; Chemotaxis, Leukocyte; Cyclic AMP; Eosinophils; Histami | 1978 |
[Comparison of natural attacks of asthma and attacks induced by exercise and inhalation of histamine or sulpyrin, with special reference to changes in vasoactive substances (author's transl)].
Topics: Aminopyrine; Asthma; Asthma, Exercise-Induced; Cyclic AMP; Cyclic GMP; Dipyrone; Dopamine beta-Hydro | 1978 |
Toluene di-isocyanate-induced asthma. I. Reactions to TDI, MDI, HDI and histamine.
Topics: Asthma; Benzhydryl Compounds; Cyanates; Hexamethonium Compounds; Histamine; Humans; Male; Toluene 2, | 1979 |
Toluene di-isocyanate-induced asthma. II. Inhalation challenge tests and bronchial reactivity studies.
Topics: Adult; Asthma; Cyanates; Exercise Test; Histamine; Humans; Middle Aged; Respiratory Function Tests; | 1979 |
In vitro studies on the mechanism of respiratory virus-induced asthma.
Topics: Asthma; Histamine; Humans; In Vitro Techniques; Influenza A virus; Influenza Vaccines; Influenza, Hu | 1979 |
Autonomic mechanisms in asthma and other allergic diseases.
Topics: Antigen-Antibody Reactions; Asthma; Child; Histamine; Humans; Hypersensitivity; Hypersensitivity, De | 1979 |
Effect of cromolyn sodium and of daily exposure to compound 48/80 on experimental asthma.
Topics: Aerosols; Animals; Asthma; Bronchi; Cromolyn Sodium; Female; Guinea Pigs; Histamine; Histamine H1 An | 1975 |
Bronchial asthma: the possible role of the chemical mediators of immediate hypersensitivity in the pathogenesis of subacute chronic disease.
Topics: Acetylcholine; Adrenergic beta-Agonists; Anaphylaxis; Asthma; Autacoids; Blood Coagulation Factors; | 1975 |
Comparative analysis of bronchial provocation tests with histamine inhalation an physical exericse in the detection and differentiation of particular diseases with bronchospasm.
Topics: Asthma; Bronchial Spasm; Bronchitis; Chronic Disease; Histamine; Humans; Lung Volume Measurements; P | 1978 |
Bronchial reactivity in Western red cedar induced asthma.
Topics: Asthma; Bronchial Provocation Tests; Forced Expiratory Volume; Histamine; Humans; Male; Middle Aged; | 1979 |
New bronchodilators. Synthesis and bronchodilating activity of some 3-(alkoxymethyl)-alpha-(N-substituted aminomethyl)-4-hydroxybenzyl alcohols.
Topics: Airway Resistance; Animals; Asthma; Benzyl Alcohols; Benzyl Compounds; Bronchodilator Agents; Chemic | 1979 |
Bronchial responsiveness to inhaled histamine and exercise.
Topics: Administration, Intranasal; Adolescent; Adult; Asthma; Bronchi; Child; Exercise Test; Female; Forced | 1979 |
Medical outcome in asthmatic patients: effects of airways hyperreactivity and symptom-focused anxiety.
Topics: Adolescent; Adult; Anxiety; Asthma; Attitude to Health; Female; Histamine; Humans; Male; Methacholin | 1979 |
[Incidence of asthma, chronic bronchitis and bronchial hyperreactivity to histamine in medical students in łódź].
Topics: Adult; Asthma; Bronchitis; Female; Histamine; Humans; Hypersensitivity, Immediate; Male; Poland; Stu | 1979 |
[Contents of biologically active substances (histamine and serotonin) in patients with bronchial asthma].
Topics: Adolescent; Adult; Asthma; Histamine; Humans; Middle Aged; Serotonin | 1979 |
Comparison of sodium nitroprusside and isoprenaline aerosols in histamine-induced bronchial asthma of the guinea pig.
Topics: Aerosols; Animals; Asthma; Ferricyanides; Guinea Pigs; Histamine; In Vitro Techniques; Isoproterenol | 1979 |
The effect of different pharmacological agents on respiratory reflexes in normal and asthmatic subjects.
Topics: Adolescent; Adult; Aerosols; Asthma; Bupivacaine; Cough; Histamine; Humans; Methacholine Compounds; | 1979 |
Histamines, basophils and eosinophils in severe asthma.
Topics: Acute Disease; Adolescent; Adrenal Cortex Hormones; Adult; Aged; Arteries; Asthma; Basophils; Blood | 1979 |
[Evaluation of the effectiveness of desensitization in bronchial asthma caused by house dust mites or grass pollen in the light of clinical results and the histamine and polymyxin inhalation test].
Topics: Adolescent; Adult; Aerosols; Allergens; Asthma; Desensitization, Immunologic; Dust; Evaluation Studi | 1979 |
[Evaluation of the relationship between vasomotor or allergic rhinitis, bronchial hyperreactivity and pulmonary ventilation].
Topics: Allergens; Asthma; Bronchi; Histamine; Humans; Hypersensitivity, Immediate; Polymyxin B; Respiration | 1979 |
Perennial atopic rhinitis as an early stage of bronchial asthma.
Topics: Adolescent; Adult; Age Factors; Allergens; Asthma; Asthma, Exercise-Induced; Female; Histamine; Huma | 1979 |
Methacholine and histamine inhalation challenges in asthma: relationships to age of onset, length of illness, and pulmonary functions.
Topics: Adolescent; Adult; Age Factors; Aged; Asthma; Bronchi; Bronchial Provocation Tests; Female; Histamin | 1979 |
Influence of small atmospheric ions on the airways in patients with bronchial asthma.
Topics: Adolescent; Adult; Air Ionization; Airway Obstruction; Asthma; Female; Forced Expiratory Volume; His | 1979 |
Isocyanate-induced asthma in an automobile spray painter.
Topics: Adult; Aerosols; Allergens; Asthma; Automobiles; Bronchi; Bronchial Provocation Tests; Cyanates; For | 1979 |
[Prostaglandins and lung function. II. Bronchial reactivity to PGF 2-alpha and histamine in bronchial asthma].
Topics: Adolescent; Adult; Aged; Asthma; Bronchi; Bronchial Provocation Tests; Female; Histamine; Humans; Ma | 1979 |
Determinants of allergen-induced asthma: dose of allergen, circulating IgE antibody concentration, and bronchial responsiveness to inhaled histamine.
Topics: Adolescent; Adult; Allergens; Asthma; Bronchi; Bronchial Provocation Tests; Female; Histamine; Human | 1979 |
Effect of ozone on bronchial reactivity in atopic and nonatopic subjects.
Topics: Adult; Aerosols; Airway Resistance; Asthma; Atropine; Bronchial Provocation Tests; Female; Histamine | 1979 |
The emerging role of bronchoprovocation.
Topics: Airway Resistance; Asthma; Bronchial Provocation Tests; Forced Expiratory Volume; Histamine; Humans; | 1979 |
Methacholine inhalation challenge studies.
Topics: Adult; Asthma; Bronchial Provocation Tests; Child; Female; Forced Expiratory Volume; Histamine; Huma | 1979 |
More implications of reactivity characteristics to methacholine and histamine in asthmatic patients.
Topics: Adolescent; Adult; Asthma; Bronchial Provocation Tests; Dose-Response Relationship, Immunologic; His | 1979 |
Physiologic effects of inhaled histamine in asthma: reversible changes in pulmonary mechanics and total lung capacity.
Topics: Airway Resistance; Asthma; Atropine; Bronchial Provocation Tests; Forced Expiratory Volume; Function | 1979 |
Indications for inhalation challenge. Study Group on Indications, Bronchoprovocation Committee, American Academy of Allergy.
Topics: Antigens; Asthma; Bronchial Provocation Tests; Carbachol; Histamine; Humans; Methacholine Compounds | 1979 |
Relationship between airways response to allergens and nonspecific bronchial reactivity.
Topics: Adolescent; Adult; Aged; Allergens; Asthma; Bronchial Provocation Tests; Female; Histamine; Humans; | 1979 |
[Reaction to control solutions in intradermal tests].
Topics: Adult; Aged; Asthma; Coca; False Positive Reactions; Histamine; Humans; Intradermal Tests; Middle Ag | 1979 |
[Bronchial reactivity to non-specific stimuli: exercise and histamine in patients with atopic and non-atopic asthma].
Topics: Adolescent; Adult; Asthma; Bronchial Provocation Tests; Female; Histamine; Humans; Hypersensitivity, | 1979 |
Experimental investigation on the pathogenesis of tartrazine-induced asthma.
Topics: Animals; Asthma; Azo Compounds; Bronchodilator Agents; Dose-Response Relationship, Drug; Drug Synerg | 1979 |
[Effect of hydrocortisone on the blood histamine level during attack of bronchial asthma].
Topics: Adult; Asthma; Female; Histamine; Hormones; Humans; Hydrocortisone; Male; Middle Aged | 1979 |
[Total blood serum IgE level and bronchial reactivity to non-specific exercise and histamine tests in allergic and non-allergic respiratory diseases].
Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Bronchi; Bronchial Provocation Tests; Child; Fe | 1979 |
Calcium hypersensitivity in airways smooth muscle. Isometric tension responses following anaphylaxis.
Topics: Anaphylaxis; Animals; Asthma; Calcium; Guinea Pigs; Histamine; Male; Muscle Tonus; Muscle, Smooth; T | 1979 |
Bronchial hyperreactivity in allergic and non-allergic rhinitis compared to allergic and non-allergic asthma.
Topics: Asthma; Bronchial Provocation Tests; Dust; Histamine; Humans; Mites; Pollen; Rhinitis; Rhinitis, All | 1979 |
Studies on histamine metabolism in intrinsic bronchial asthma.
Topics: Acute Disease; Adolescent; Adrenal Cortex Hormones; Adult; Aged; Asthma; Female; Histamine; Humans; | 1979 |
Effects of experimental rhinovirus 16 infection on airways and leukocyte function in normal subjects.
Topics: Adult; Antibody-Dependent Cell Cytotoxicity; Asthma; Common Cold; Female; Histamine; Humans; Isoprot | 1978 |
[Analysis of asthma reactions caused by histamine or serotonin in the guinea pig (author's transl)].
Topics: Animals; Asthma; Blood Pressure; Guinea Pigs; Heart Rate; Histamine; Respiration; Serotonin; Time Fa | 1978 |
Allergen-induced increase in non-allergic bronchial reactivity.
Topics: Allergens; Asthma; Forced Expiratory Volume; Histamine; Humans; Methacholine Compounds; Time Factors | 1977 |
Bronchial reactivity in cystic fibrosis.
Topics: Adolescent; Adult; Aerosols; Airway Resistance; Asthma; Bronchi; Child; Cystic Fibrosis; Female; For | 1978 |
Distribution of pulmonary responsiveness to aerosol histamine in dogs.
Topics: Aerosols; Airway Resistance; Animals; Asthma; Dogs; Dose-Response Relationship, Drug; Drug Hypersens | 1978 |
Comparative study of histamine and exercise challenges in asthmatic children.
Topics: Adolescent; Adult; Asthma; Bronchial Spasm; Child; Female; Forced Expiratory Flow Rates; Forced Expi | 1978 |
Histamine in nasal secretions.
Topics: Adolescent; Adult; Asthma; Female; Histamine; Humans; Male; Mucus; Nasal Mucosa; Rhinitis, Allergic, | 1978 |
[Bronchial reactivity to exercise and histamine in patients with seasonal rhinitis].
Topics: Adult; Asthma; Diagnosis, Differential; Histamine; Humans; Middle Aged; Physical Exertion; Rhinitis, | 1978 |
[Incidence of bronchial hyperreactivity and tendency for developing bronchial asthma in patients with non-allergic rhinitis].
Topics: Adult; Asthma; Bronchi; Female; Histamine; Humans; Male; Middle Aged; Rhinitis, Allergic, Seasonal | 1978 |
Bronchial responsiveness to inhaled histamine and isoprenaline in patients with airway obstruction.
Topics: Adult; Airway Obstruction; Airway Resistance; Asthma; Bronchi; Bronchitis; Chronic Disease; Histamin | 1978 |
Bronchoconstrictive suggestion in asthma: a role for airways hyperreactivity and emotions.
Topics: Adolescent; Adult; Airway Resistance; Asthma; Emotions; Female; Histamine; Humans; Male; Methacholin | 1978 |
Asthma, allergy and bronchial hyper-reactivity to histamine in patients with bronchiectasis.
Topics: Adolescent; Adult; Aged; Asthma; Bronchi; Bronchiectasis; Female; Histamine; Humans; Male; Middle Ag | 1978 |
Gas exchange during acute experimental canine asthma.
Topics: Acute Disease; Allergens; Animals; Ascaris; Asthma; Dogs; Histamine; Methacholine Compounds; Ventila | 1978 |
Bronchial hyperreactivity in cystic fibrosis and asthma.
Topics: Adolescent; Adult; Asthma; Bronchi; Child; Cystic Fibrosis; Dose-Response Relationship, Drug; Female | 1978 |
Histamine and acetaminophen--a reader's "untoward" reaction.
Topics: Acetaminophen; Aspirin; Asthma; Histamine; Humans | 1978 |
Reproducibility and comparison of responses to inhaled histamine and methacholine.
Topics: Adult; Aerosols; Asthma; Bronchi; Dose-Response Relationship, Drug; Forced Expiratory Volume; Histam | 1978 |
The relation between magnesium, blood histamine level and eosinophilia in the acute stage of the allergic reactions in humans.
Topics: Acute Disease; Asthma; Eosinophils; Erythrocytes; Histamine; Humans; Hypersensitivity, Immediate; Le | 1978 |
Blood histamine level and histamine content in the lung tissue in immediate immunological reactions in human and experimental animals.
Topics: Animals; Asthma; Female; Guinea Pigs; Histamine; Humans; Hypersensitivity, Immediate; Lung; Male | 1978 |
Importance of respiratory allergy in provoking reversible bronchial obstruction.
Topics: Aerosols; Allergens; Asthma; Bronchial Spasm; Histamine; Humans; Skin Tests | 1978 |
The effect of cholinergic and anticholinergic agents on the primate model of allergic asthma.
Topics: Airway Resistance; Animals; Antigens; Asthma; Atropine; Carbachol; Disease Models, Animal; Female; H | 1976 |
Effect of histamine and methacholine on nasal airway resistance in atopic and nonatopic subjects. Comparison with bronchial challenge and skin test responses.
Topics: Airway Resistance; Asthma; Bronchi; Dose-Response Relationship, Drug; Histamine; Humans; Hypersensit | 1977 |
[Blood histamine levels in various clinical states in asthma].
Topics: Acute Disease; Asthma; Histamine; Humans; Remission, Spontaneous | 1977 |
Effects of intravenous histamine on pulmonary mechanics in nonasthmatic and asthmatic subjects.
Topics: Adult; Asthma; Female; Histamine; Humans; Lung Compliance; Male; Pulmonary Ventilation; Residual Vol | 1977 |
Changes in arterial oxygen saturation in patients with hyperreactive airways during a histamine inhalation test.
Topics: Adult; Aged; Asthma; Bronchial Spasm; Female; Histamine; Humans; Hypoxia; Male; Middle Aged; Oxygen; | 1977 |
[Evaluation of bronchial reactivity in children after subglottic laryngitis].
Topics: Adolescent; Asthma; Bronchi; Child; Child, Preschool; Female; Histamine; Humans; Laryngitis; Male; S | 1977 |
[Specific features of histamine metabolism and the adrenal cortex function in different types of bronchial asthma].
Topics: Adolescent; Adrenal Cortex; Adrenal Glands; Adult; Aged; Asthma; Female; Histamine; Humans; Male; Mi | 1977 |
The effect of metiamide in in vitro and in vivo canine models of type I hypersensitivity reactions.
Topics: Airway Resistance; Animals; Ascaris; Asthma; Dogs; Histamine; Hypersensitivity, Immediate; In Vitro | 1977 |
[Change in serotonin and histamine content of blood in chronic nonspecific lung diseases].
Topics: Asthma; Chronic Disease; Histamine; Humans; Lung Diseases; Serotonin | 1977 |
Changes in airway mast cells and histamine caused by antigen aerosol in allergic dogs.
Topics: Aerosols; Airway Resistance; Animals; Antigens; Ascaris; Asthma; Bronchi; Dogs; Histamine; Mast Cell | 1977 |
Eosinophil chemotaxis to an ECF-A tetrapeptide and histamine: the response in various disease states.
Topics: Arthritis, Rheumatoid; Asthma; Chemotaxis, Leukocyte; Dose-Response Relationship, Drug; Eosinophilia | 1977 |
Bronchial reactivity to inhaled histamine: a method and clinical survey.
Topics: Adult; Aerosols; Asthma; Bronchi; Cough; Dose-Response Relationship, Drug; Female; Forced Expiratory | 1977 |
Bronchial reactivity: interaction between vagal stimulation and inhaled histamine.
Topics: Aerosols; Airway Resistance; Animals; Asthma; Bronchi; Dogs; Dose-Response Relationship, Drug; Elect | 1977 |
Opposite changes in blood histamine and force expiratory volume during bronchial inhalation challenge.
Topics: Adolescent; Adult; Antigens; Asthma; Dust; Female; Forced Expiratory Volume; Histamine; Humans; Male | 1977 |
The relationship of plasma histamine to the activity of bronchial asthma.
Topics: Adolescent; Adult; Aged; Asthma; Female; Histamine; Humans; Male; Middle Aged; Rhinitis, Allergic, S | 1977 |
[Experimental investigation on the pathogenesis of aspirin-induced asthma--the effects of aspirin on the contraction of guinea-pig tracheal tissues with various bronchoconstrictors (author's transl)].
Topics: Acetylcholine; Animals; Aspirin; Asthma; Bradykinin; Dose-Response Relationship, Drug; Drug Synergis | 1977 |
Inhibition of histamin-induced airway constriction negative results with oxtriphylline and ascorbic acid.
Topics: Ascorbic Acid; Asthma; Constriction, Pathologic; Histamine; Theophylline | 1977 |
Bronchial reactivity to prostaglandins F2alpha, E2, and histamine in different types of asthma.
Topics: Adult; Aerosols; Aged; Aspirin; Asthma; Bronchi; Dose-Response Relationship, Drug; Female; Histamine | 1977 |
Factors in allergen-induced asthma: relevance of the intensity of the airways allergic reaction and non-specific bronchial reactivity.
Topics: Adolescent; Adult; Aerosols; Asthma; Bronchial Spasm; Environment, Controlled; Environmental Exposur | 1976 |
The effect of cholinergic agents on a canine model of allergic asthma.
Topics: Administration, Intranasal; Airway Resistance; Animals; Antigens; Ascaris; Asthma; Atropine; Chloris | 1976 |
The relationship between bronchial histamine reactivity and atopic status.
Topics: Asthma; Bronchi; Histamine; Humans; Hypersensitivity, Immediate; Immunoglobulin E; Skin Tests | 1976 |
Bronchoconstriction reflex in bronchial asthma.
Topics: Acetylcholine; Adult; Airway Resistance; Asthma; Bronchial Spasm; Histamine; Humans; Reflex | 1976 |
[Speleotherapy in Bystrá and Gombasek Caves. Changes in some biochemical indices in patients with bronchial asthma and in controls (author's transl)].
Topics: Asthma; Climate; Geological Phenomena; Geology; Histamine; Humans; Physical Therapy Modalities; Sero | 1976 |
Oral aspirin challenges in asthmatic patients: a study of plasma histamine.
Topics: Administration, Oral; Adult; Aged; Aspirin; Asthma; Drug Hypersensitivity; Female; Forced Expiratory | 1976 |
[Usefulness of exercise-induced bronchospasm as compared with histamine inhalation test in the detection and differential diagnosis of asthma and some forms of chronic bronchitis].
Topics: Asthma; Bronchi; Bronchial Spasm; Bronchitis; Chronic Disease; Diagnosis, Differential; Histamine; H | 1976 |
[Occupational bronchial asthma and pathochemical methods of its evaluation].
Topics: Asthma; Fibrinogen; Fibrinolysis; Heparin; Histamine; Humans; Neuraminic Acids; Occupational Disease | 1976 |
[Diagnostic bronchomotoric test].
Topics: Airway Obstruction; Asthma; Bronchial Diseases; Histamine; Humans; Respiratory Insufficiency; Ventil | 1976 |
The mechanism of rapid, shallow breathing after inhaling histamine aerosol in exercising dogs.
Topics: Aerosols; Airway Resistance; Animals; Asthma; Atropine; Blood Gas Analysis; Dogs; Dose-Response Rela | 1976 |
Plasma histamine changes during provoked bronchospasm in asthmatic patients.
Topics: Administration, Intranasal; Adult; Antigens; Asthma; Basophils; Bronchial Spasm; Eosinophils; Female | 1976 |
[Possibilities of evaluating the allergic terrain in childhood. Importance of the serum histamine binding capacity].
Topics: Asthma; Child; Child, Preschool; Female; Histamine; Humans; Hypersensitivity; Latex Fixation Tests; | 1976 |
Histamine levels in plasma, blood, and urine in severe asthma, and the effect of corticosteroid treatment.
Topics: Adult; Aged; Asthma; Female; Histamine; Humans; Hydrocortisone; Male; Middle Aged | 1976 |
Bronchial histamine reactivity: its relationship to the reactivity of the bronchi to allergens.
Topics: Administration, Intranasal; Allergens; Arthrodermataceae; Asthma; Bronchi; Dose-Response Relationshi | 1976 |
[Mucus transport in asthma].
Topics: Acetylcholine; Animals; Antigens; Ascaris; Asthma; Biological Transport; Dogs; Histamine; Lung Compl | 1976 |
Protective effect of allopurinol on bronchiolar constriction induced by histamine.
Topics: Adenine Nucleotides; Allopurinol; Animals; Asthma; Bronchodilator Agents; Guinea Pigs; Histamine; Lu | 1976 |
[Pathogenesis of bronchial asthma].
Topics: Asthma; Histamine; Humans; Immunoglobulin E; Mast Cells; T-Lymphocytes | 1976 |
Mechanical properties of the lungs and experimental asthma in conscious allergic dogs.
Topics: Airway Resistance; Allergens; Animals; Ascaris; Asthma; Bronchi; Constriction; Disease Models, Anima | 1975 |
The unreliability of the maximal midexpiratory flow as an index of acute airway changes.
Topics: Adolescent; Adult; Airway Obstruction; Airway Resistance; Asthma; Dilatation; Female; Histamine; Hum | 1975 |
[Histamine inhalation test in chronic disease syndromes accompanied by bronchial spasm].
Topics: Adolescent; Adult; Asthma; Bronchial Diseases; Bronchial Spasm; Bronchitis; Chronic Disease; Diagnos | 1975 |
Potentiating effect of D-2-O on the ascaris-induced, reagin-mediated model of asthma in the Rhesus monkey studied with a double aerosolized antigen challenge technique.
Topics: Aerosols; Animals; Antibodies; Antigens; Ascaris; Asthma; Deuterium; Drug Synergism; Histamine; Immu | 1975 |
Effects of inhaled prostaglandins E1, E2, and F2alpha on the airway resistance of healthy and asthmatic man.
Topics: Adolescent; Adult; Aerosols; Airway Resistance; Asthma; Histamine; Humans; Isoproterenol; Male; Midd | 1975 |
[Serotonin, histamine and acetylcholine in bronchial asthma (author's transl)].
Topics: Acetylcholine; Adolescent; Adult; Asthma; Bronchial Spasm; Female; Histamine; Humans; Male; Serotoni | 1975 |
Nitrogen and bolus closing volumes: differences after histamine-induced bronchoconstriction.
Topics: Adult; Aerosols; Airway Resistance; Asthma; Bronchi; Constriction; Female; Fluorides; Functional Res | 1975 |
Arterial and muscle oxygen tension in experimental models of asthma. Experimental models of asthma.
Topics: Animals; Antibody Formation; Ascaris; Asthma; Catheterization; Choline; Disease Models, Animal; Dogs | 1975 |
[Blood histamine levels in allergology: effect of specific desensitization and of animal immunization].
Topics: Adolescent; Adult; Aged; Animals; Asthma; Desensitization, Immunologic; Histamine; Humans; Hypersens | 1975 |
[Allergentesting in children with asthma bronchiale (author's transl)].
Topics: Adolescent; Allergens; Animals; Asthma; Bronchi; Child; Child, Preschool; Dust; Feathers; Hair; Hist | 1975 |
Letter: Experimental asthma in conscious allergic dogs.
Topics: Airway Resistance; Animals; Antigens; Asthma; Atropine; Disease Models, Animal; Dogs; Histamine; Iso | 1975 |
A comparison of methacholine and histamine inhalations in asthmatics.
Topics: Administration, Intranasal; Adolescent; Adrenal Cortex Hormones; Adult; Aged; Asthma; Dose-Response | 1975 |
The influence of procaine and isoprenaline on the lung deflation reflex during the histamine-induced bronchial asthma attack.
Topics: Aerosols; Airway Resistance; Animals; Asthma; Guinea Pigs; Heart; Histamine; Injections; Injections, | 1975 |
Reflex control of airways smooth muscle.
Topics: Air Pollutants; Airway Resistance; Animals; Asthma; Cats; Histamine; Humans; Muscle Contraction; Mus | 1975 |
Mechanisms of bronchial hyperreactivity in normal subjects after upper respiratory tract infection.
Topics: Aerosols; Airway Resistance; Asthma; Atropine; Bronchi; Bronchial Diseases; Citrates; Histamine; Hum | 1976 |
Cytomorphological variations and blood histamine in bronchial asthma.
Topics: Acute Disease; Adolescent; Adult; Asthma; Basophils; Child; Eosinophils; Female; Histamine; Humans; | 1976 |
[Action of pharmacodynamic substances on bronchial motility in relation to their administration route].
Topics: Acetylcholine; Aerosols; Animals; Asthma; Bradykinin; Bronchi; Bronchodilator Agents; Cats; Dogs; Hi | 1976 |
[CARD in children; a 5 years longitudinal study].
Topics: Adolescent; Air Pollution; Asthma; Child; Cough; Female; Forced Expiratory Flow Rates; Histamine; Hu | 1976 |
RP 58802B, a long-acting beta 2-adrenoceptor agonist: assessment of antiasthma activity in the guinea-pig in vivo.
Topics: Administration, Inhalation; Administration, Oral; Adrenergic beta-Agonists; Albuterol; Anesthesia; A | 1992 |
CR 2039, a new bis-(1H-tetrazol-5-yl)phenylbenzamide derivative with potential for the topical treatment of asthma.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Administration, Inhalation; Anaphylaxis; Animals; Asthma; Benza | 1992 |
[Influence of histaglobin therapy on skin tests and clinical symptoms in patients with atopic bronchial asthma].
Topics: Adult; Aged; Asthma; Drug Combinations; Female; gamma-Globulins; Histamine; Humans; Male; Middle Age | 1992 |
[Bivalent cations of the bronchial contents in the pathogenesis and clinical picture of bronchial asthma].
Topics: Adolescent; Adult; Asthma; Breath Tests; Bronchi; Bronchial Hyperreactivity; Bronchial Provocation T | 1992 |
Adenosine-induced bronchoconstriction in an allergic rabbit model: antagonism by theophylline aerosol.
Topics: Adenosine; Aerosols; Anesthesia; Animals; Asthma; Bronchial Hyperreactivity; Histamine; Pollen; Rabb | 1992 |
Modification of allergen-induced airway obstruction and bronchial hyperresponsiveness in the allergic rabbit by theophylline aerosol.
Topics: Aerosols; Airway Obstruction; Airway Resistance; Allergens; Animals; Asthma; Bronchial Hyperreactivi | 1992 |
[Effect of loratadine (LO), a selective H1 antagonist, on histamine-induced bronchoconstriction].
Topics: Adult; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Female; Histamine; Humans; Loratadi | 1992 |
[Effect of cetirizine, selective H1 antagonist of histamine on skin and bronchial reactivity and cellular histamine release in allergic diseases].
Topics: Asthma; Bronchial Provocation Tests; Cetirizine; Chronic Disease; Histamine; Humans; Neutrophils; Rh | 1992 |
[The effect of muscarinic receptor blockers on non-specific bronchial reactivity in patients with bronchial asthma].
Topics: Adult; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Choline; Female; Histamine; Humans; Ipr | 1992 |
Bronchoalveolar cell count and its relationship to bronchial hyperreactivity after antigen challenge in asthmatics.
Topics: Adolescent; Adult; Antigens, Bacterial; Asthma; Bronchial Provocation Tests; Bronchoalveolar Lavage | 1992 |
Urinary excretion of leukotriene E4 and 11-dehydro-thromboxane B2 in response to bronchial provocations with allergen, aspirin, leukotriene D4, and histamine in asthmatics.
Topics: Adult; Allergens; Aspirin; Asthma; Bronchial Provocation Tests; Female; Histamine; Humans; Leukotrie | 1992 |
Urinary leukotriene E4 in bronchial asthma.
Topics: Adult; Aspirin; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Drug Hypersensitivit | 1992 |
Circulating histamine and eosinophil cationic protein levels in nocturnal asthma.
Topics: Adolescent; Adult; Asthma; Blood Proteins; Circadian Rhythm; Eosinophils; Female; Histamine; Humans; | 1992 |
Enhanced production of oxygen radicals in nocturnal asthma.
Topics: Adult; Asthma; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Bronchoscopy; Circadian Rh | 1992 |
Induction by aerosol allergen of sustained and nonspecific IgE-mediated airway hyperreactivity in the guinea pig.
Topics: Acetylcholine; Aerosols; Allergens; Animals; Asthma; Bronchial Hyperreactivity; Diphenhydramine; Gui | 1992 |
Mediator concentrations in bronchoalveolar lavage fluid of patients with mild asymptomatic bronchial asthma.
Topics: Administration, Inhalation; Adolescent; Adult; Asthma; Autacoids; Bronchoalveolar Lavage Fluid; Cell | 1992 |
Stimulation of cyclic AMP production in human alveolar macrophages induced by inflammatory mediators and beta-sympathicomimetics.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adult; Aged; Albuterol; Asthma; Cyclic AMP; Dinoproston | 1992 |
Effect of NZ-107, a newly synthesized pyridazinone derivative, on antigen-induced contraction of human bronchial strips and histamine release from human lung fragments or leukocytes.
Topics: Aminopyridines; Asthma; Bronchi; Bronchoconstriction; Cromolyn Sodium; Histamine; Histamine Release; | 1992 |
The effect of inhaled allergen on circulating basophils in atopic asthma.
Topics: Adult; Allergens; Asthma; Basophils; Blood Cells; Forced Expiratory Volume; Histamine; Histamine Rel | 1992 |
[The role of serotonin, histamine and the kallikrein-kinin system in the pathogenesis of asphyxic attacks in bronchial asthma].
Topics: Asphyxia; Asthma; Histamine; Humans; Hydroxyindoleacetic Acid; Kallikrein-Kinin System; Kallikreins; | 1992 |
[Bronchial hyperreactivity in patients with asthma].
Topics: Acetylcholine; Asthma; Bronchi; Bronchial Hyperreactivity; Bronchial Provocation Tests; Cytokines; E | 1992 |
Relation of dose-response slope to respiratory symptoms and lung function in a population study of adults living in Busselton, Western Australia.
Topics: Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Dose-Response Relationship, D | 1992 |
Inhaled steroids modify bronchial responses to hyperosmolar saline.
Topics: Administration, Inhalation; Adolescent; Adult; Asthma; Beclomethasone; Bronchi; Bronchial Provocatio | 1992 |
Induction of transient airway hyperresponsiveness by exposure to 4 ppm nitrogen dioxide in guinea pigs.
Topics: Administration, Inhalation; Air Pollutants; Airway Resistance; Animals; Asthma; Bronchial Hyperreact | 1992 |
[Peripheral airway obstruction and treatment].
Topics: Administration, Inhalation; Airway Obstruction; Animals; Asthma; Asthma, Exercise-Induced; Beclometh | 1992 |
[The role of bronchial responsiveness to leukotrienes in antigen-induced immediate and late asthmatic response].
Topics: Adolescent; Adult; Animals; Antigens; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests | 1992 |
Bradykinin and other inflammatory mediators in BAL-fluid from patients with active pulmonary inflammation.
Topics: Asthma; Bradykinin; Bronchoalveolar Lavage Fluid; Histamine; Humans; Inflammation; Lung Diseases; Pe | 1992 |
Inspiratory muscle strength and endurance during hyperinflation and histamine induced bronchoconstriction.
Topics: Adult; Asthma; Bronchoconstriction; Exercise Test; Fatigue; Female; Forced Expiratory Volume; Functi | 1992 |
Atopy and bronchial responsiveness in random population sample of 527 children and adolescents.
Topics: Adolescent; Allergens; Asthma; Birth Weight; Bronchi; Bronchial Provocation Tests; Child; Exercise; | 1992 |
Histamine-induced bronchoconstriction in conscious guinea pigs measured by strain-gauge transduction. A new method.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstriction; Female | 1992 |
Development of increased airway responsiveness in two nurses performing methacholine and histamine challenge tests.
Topics: Adult; Aerosols; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Female; Histamine; | 1992 |
Histamine challenge in young children using computerized lung sounds analysis.
Topics: Adolescent; Asthma; Auscultation; Bronchial Provocation Tests; Child; Child, Preschool; Female; Four | 1992 |
Toward a definition of asthma for epidemiology.
Topics: Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Child; Follow-Up Studies; Forced Exp | 1992 |
Development of lung function in relation to increased degree of bronchial responsiveness.
Topics: Adolescent; Airway Resistance; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Child | 1992 |
Underdiagnosis of asthma in young adults presenting for USAF basic training.
Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Bronchial Provocation Tests; Diagnostic Errors; | 1992 |
Bronchial responsiveness to exercise in a random sample of 494 children and adolescents from Copenhagen.
Topics: Adolescent; Asthma; Bronchi; Child; Exercise; Forced Expiratory Volume; Histamine; Humans | 1992 |
Mortality and decline in lung function in 213 adults with bronchial asthma: a ten-year follow up.
Topics: Adolescent; Adult; Asthma; Bronchial Provocation Tests; Female; Follow-Up Studies; Forced Expiratory | 1992 |
Characteristics and diagnoses of cockroach-sensitive bronchial asthma.
Topics: Adolescent; Adult; Aged; Allergens; Animals; Asthma; Cockroaches; Female; Histamine; Humans; Immunog | 1992 |
Longitudinal study of bronchial hyperreactivity in preschool children with bronchial asthma.
Topics: Administration, Inhalation; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Child; C | 1992 |
Characteristics of peripheral blood eosinophils in patients with nocturnal asthma.
Topics: Adult; Asthma; Bronchial Provocation Tests; Cell Survival; Circadian Rhythm; Eosinophils; Female; Hi | 1992 |
[Bronchial hyperresponsiveness to histamine induced by intravenous administration of prostaglandin D2 (PGD2) in guinea pigs].
Topics: Airway Resistance; Animals; Asthma; Bridged Bicyclo Compounds; Bronchial Hyperreactivity; Edema; Fat | 1992 |
[Urinary N-methylhistamine excretion. Following exogenous histamine administration and allergy/exercise-induced bronchoconstriction].
Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Bronchial Provocation Tests; Child; Child, Pres | 1992 |
Bronchial allergen challenge: dose versus concentration.
Topics: Adolescent; Adult; Allergens; Asthma; Bronchi; Bronchial Provocation Tests; Dose-Response Relationsh | 1992 |
Increased plasma tumour necrosis factor-alpha concentration in atopic dermatitis.
Topics: Adolescent; Asthma; Child; Child, Preschool; Dermatitis, Atopic; Female; Histamine; Humans; Infant; | 1992 |
Occupational asthma: validity of monitoring of peak expiratory flow rates and non-allergic bronchial responsiveness as compared to specific inhalation challenge.
Topics: Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Female; Histamine; Humans; Ma | 1992 |
Relation between the bronchial obstructive response to inhaled lipopolysaccharide and bronchial responsiveness to histamine.
Topics: Administration, Inhalation; Adult; Aged; Asthma; Bronchi; Bronchoconstriction; Female; Forced Expira | 1992 |
Effects of NZ-107 on bronchoconstriction in guinea pigs.
Topics: Albuterol; Animals; Asthma; Bronchoconstriction; Cromolyn Sodium; Disease Models, Animal; Guinea Pig | 1992 |
[Bronchial hyperresponsiveness to histamine induced by intravenous administration of leukotriene C4 (LTC4) and LTD4 in guinea pigs].
Topics: Airway Resistance; Animals; Asthma; Bronchi; Bronchial Hyperreactivity; Chromones; Guinea Pigs; Hist | 1992 |
Assessment of bronchodilatation after spontaneous recovery from a histamine challenge in asthmatic children.
Topics: Adolescent; Albuterol; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Child; Female; Forc | 1992 |
Platelet-activating factor (PAF) plays an important role in the immediate asthmatic response in guinea-pig by augmenting the response to histamine.
Topics: Anaphylaxis; Animals; Asthma; Bronchi; Guinea Pigs; Histamine; Male; Ovalbumin; Platelet Activating | 1992 |
Effect of erythromycin on bronchial hyperresponsiveness in patients with bronchial asthma.
Topics: Adult; Aged; Asthma; Bronchi; Chemotaxis, Leukocyte; Erythromycin; Female; Histamine; Humans; In Vit | 1991 |
[The changes in cell population and chemical mediators in BALF following local allergen challenge].
Topics: Adolescent; Adult; Allergens; Asthma; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Eos | 1991 |
Characteristics of two lines of guinea pigs (BHS and BHR) differing in bronchial sensitivity to acetylcholine and histamine exposure.
Topics: Acetylcholine; Airway Resistance; Animals; Antibody Formation; Asthma; Disease Models, Animal; Femal | 1991 |
Interaction of thromboxane A2 and leukotrienes in guinea pig airways in vivo.
Topics: Administration, Inhalation; Animals; Asthma; Bridged Bicyclo Compounds; Bronchoconstriction; Dose-Re | 1991 |
Possible roles of the peripheral vagal nerve in histamine-induced bronchoconstriction in guinea-pigs.
Topics: Animals; Asthma; Atropine; Bronchoconstriction; Female; Ganglionic Blockers; Guinea Pigs; Hexamethon | 1991 |
Airway levels of mast cell-derived mediators in exercise-induced asthma.
Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Autacoids; Bronchoalveolar Lavage Fluid; Cell C | 1990 |
Altered production of histamine-releasing factor (HRF) activity and responsiveness to HRF after immunotherapy in children with asthma.
Topics: Asthma; Biomarkers, Tumor; Child; Granulocytes; Histamine; Histamine Release; Humans; Immunotherapy; | 1990 |
Substance p-induced cutaneous and bronchial reactions in children with bronchial asthma.
Topics: Adolescent; Adult; Asthma; Bronchial Provocation Tests; Child; Child, Preschool; Erythema; Female; F | 1991 |
Effect of antiallergic agents and bronchial hypersensitivity in short-term bronchial asthma.
Topics: Adult; Aged; Asthma; Bronchial Provocation Tests; Cromolyn Sodium; Female; Forced Expiratory Volume; | 1991 |
[Chemical mediators and anti-mediator drugs].
Topics: Asthma; Chemotactic Factors, Eosinophil; Cromolyn Sodium; Cytokines; Depression, Chemical; Histamine | 1991 |
Tryptase and histamine release during aspirin-induced respiratory reactions.
Topics: Administration, Oral; Adult; Aspirin; Asthma; Forced Expiratory Volume; Histamine; Histamine Release | 1991 |
Neutrophil chemotactic activity of PAF, histamine and neuromediators in bronchial asthma.
Topics: Adolescent; Adult; Asthma; Chemotaxis, Leukocyte; Histamine; Humans; Middle Aged; Neuropeptides; Neu | 1991 |
Release of mediators from human gastric mucosa and blood in adverse reactions to benzoate.
Topics: 6-Ketoprostaglandin F1 alpha; Adolescent; Adult; Aged; Asthma; Benzoates; Benzoic Acid; Dermatitis, | 1991 |
Effect of passive smoking on asthmatic children who have and who have not had atopic dermatitis.
Topics: Adolescent; Asthma; Bronchial Provocation Tests; Child; Dermatitis, Atopic; Forced Expiratory Volume | 1992 |
Sensitivity and specificity of histamine PC20 determination in a random selection of young college students.
Topics: Adult; Asthma; Bronchial Provocation Tests; Female; Forced Expiratory Volume; Histamine; Humans; Mal | 1992 |
Airway hyperresponsiveness and the clinical diagnosis of asthma: histamine or history?
Topics: Asthma; Bronchi; Bronchial Provocation Tests; Histamine; Humans | 1992 |
Elevated bronchoalveolar lavage histamine in allergic asthmatics associated with increased airway obstruction.
Topics: Asthma; Bronchoalveolar Lavage Fluid; Histamine; Humans; Pulmonary Ventilation | 1992 |
[Changes in respiratory resistance and dynamic compliance induced by histamine in the guinea pig].
Topics: Airway Resistance; Animals; Asthma; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Inject | 1991 |
Sensitivity and specificity of the histamine challenge test for the diagnosis of asthma in an unselected sample of children and adolescents.
Topics: Adolescent; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Child; Evaluation Studie | 1991 |
Circadian rhythm in airway responsiveness and airway tone in patients with mild asthma.
Topics: Adolescent; Adult; Aged; Asthma; Circadian Rhythm; Female; Forced Expiratory Volume; Histamine; Huma | 1991 |
Bronchial reactivity in patients undergoing long-term haemodialysis for chronic renal failure.
Topics: Adult; Asthma; Bronchial Hyperreactivity; Female; Histamine; Humans; Kidney Failure, Chronic; Male; | 1991 |
T lymphocytes bearing histamine receptors in patients with digestive neoplasm.
Topics: Adolescent; Adult; Aged; Asthma; Digestive System Neoplasms; Female; Histamine; Humans; Immunity, Ce | 1991 |
The interaction of acetylcholine and histamine on human bronchial smooth muscle contraction.
Topics: Acetylcholine; Asthma; Atropine; Bronchi; Dose-Response Relationship, Drug; Drug Interactions; Epith | 1991 |
Verapamil in the prophylaxis of bronchial asthma. Is the bronchoprotective effect related to the plasma level?
Topics: Administration, Inhalation; Administration, Oral; Adolescent; Adult; Asthma; Female; Histamine; Huma | 1991 |
[Bronchial hyperresponsiveness to histamine induced by intravenous administration of thromboxane A2 (TXA2) in guinea-pigs].
Topics: Airway Resistance; Animals; Asthma; Bridged Bicyclo Compounds; Bronchial Hyperreactivity; Fatty Acid | 1991 |
A stable isotope dilution mass spectrometric assay for the major urinary metabolite of PGD2.
Topics: Asthma; Bronchoalveolar Lavage Fluid; Histamine; Humans; Hydroxyprostaglandin Dehydrogenases; Hyperc | 1991 |
[Histamine inhalation test in patients with specific bronchial hyperreactivity].
Topics: Administration, Inhalation; Adolescent; Adult; Allergens; Animals; Antigens, Dermatophagoides; Asthm | 1991 |
Plasma histamine, epinephrine, cortisol, and leukocyte beta-adrenergic receptors in nocturnal asthma.
Topics: Asthma; Binding, Competitive; Cell Separation; Chromatography, High Pressure Liquid; Circadian Rhyth | 1991 |
Hyperreactivity and 45Ca movements in sensitized guinea-pig tracheal muscle.
Topics: Animals; Asthma; Calcium Radioisotopes; Guinea Pigs; Histamine; Immunization; Male; Muscle Contracti | 1991 |
Robust trend analysis in predicting histamine provocation concentration.
Topics: Algorithms; Asthma; Bronchial Provocation Tests; Forced Expiratory Volume; Histamine; Humans; Least- | 1991 |
Repeatability of histamine bronchial challenge and comparability with methacholine bronchial challenge in a population of Australian schoolchildren.
Topics: Asthma; Bronchial Provocation Tests; Bronchoconstriction; Dose-Response Relationship, Drug; Evaluati | 1991 |
Effect of cyclosporin-A treatment on endotoxin-induced airway hyperreactivity in vivo and in vitro in guinea-pigs.
Topics: Animals; Asthma; Cyclosporins; Dose-Response Relationship, Drug; Endotoxins; Guinea Pigs; Histamine; | 1991 |
[Bronchial hyperresponsiveness to histamine following antigen challenges in actively sensitized guinea pigs].
Topics: Airway Resistance; Animals; Asthma; Disease Models, Animal; Guinea Pigs; Histamine; Lung Compliance; | 1991 |
Priority of peak circadian variation of bronchial responsiveness to the trough of circadian variation of bronchial caliber in asthmatic children.
Topics: Asthma; Bronchi; Bronchial Provocation Tests; Child; Circadian Rhythm; Female; Forced Expiratory Vol | 1991 |
Relation of dose-response slope to respiratory symptoms in a population of Australian schoolchildren.
Topics: Asthma; Bronchial Provocation Tests; Child; Dose-Response Relationship, Drug; Forced Expiratory Volu | 1991 |
Muscarinic-receptor functioning in tracheas from normal and ovalbumin-sensitive guinea pigs.
Topics: Aerosols; Animals; Asthma; Bethanidine; Electric Stimulation; Female; Gallamine Triethiodide; Guinea | 1991 |
Inflammatory mediators and cellular infiltration of the lungs in a guinea pig model of the late asthmatic reaction.
Topics: Albumins; Animals; Asthma; Bronchoalveolar Lavage Fluid; Cell Count; Glucuronidase; Guinea Pigs; His | 1991 |
Spontaneous changes in bronchial responsiveness in children and adolescents: an 18-month follow-up.
Topics: Adolescent; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Child; Exercise Test; Fe | 1991 |
[Experiences with Cockcroft's modified inhalation provocation test with histamine using the Pari provocation test I].
Topics: Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Dose-Response Relationship, Drug; Hi | 1991 |
Citric acid cough threshold and airway responsiveness in asthmatic patients and smokers with chronic airflow obstruction.
Topics: Adult; Asthma; Bronchoconstriction; Citrates; Citric Acid; Cough; Female; Forced Expiratory Volume; | 1991 |
Comparison of airway responsiveness to prostaglandin D2 and histamine, methacholine or exercise in healthy and asthmatic subjects.
Topics: Adult; Airway Resistance; Asthma; Female; Forced Expiratory Volume; Histamine; Humans; Male; Methach | 1991 |
IgE-mediated inhalant allergy against human corticotropin-releasing hormone.
Topics: Adult; Asthma; Basophils; Blotting, Western; Bronchial Provocation Tests; Corticotropin-Releasing Ho | 1991 |
[Difference of tolerances to isoprenaline between tracheal and vascular smooth muscles and cardiac conduction system in guinea pigs].
Topics: Animals; Asthma; Blood Pressure; Drug Tolerance; Female; Guinea Pigs; Heart Rate; Histamine; Isoprot | 1990 |
Inhibitory effect of HSR-6071, a new anti-allergic agent, on experimental asthma in rats and guinea-pigs.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Aminopyridines; Animals; Asthma; Azoles; Bronchi; Cromolyn Sodi | 1990 |
Allergen-induced asthmatic responses. Relationship between increases in airway responsiveness and increases in circulating eosinophils, basophils, and their progenitors.
Topics: Allergens; Asthma; Basophils; Blood Cell Count; Colony-Forming Units Assay; Eosinophils; Histamine; | 1991 |
Abnormalities in airway smooth muscle in fatal asthma. A comparison between trachea and bronchus.
Topics: Acetylcholine; Adult; Asthma; Bronchi; Bronchoconstriction; Electric Stimulation; Female; Histamine; | 1991 |
Bronchoalveolar lavage fluid mediator levels 5 minutes after allergen challenge in atopic subjects with asthma: relationship to the development of late asthmatic responses.
Topics: Adolescent; Adult; Allergens; Asthma; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; For | 1991 |
Erythromycin reduces the severity of bronchial hyperresponsiveness in asthma.
Topics: Adult; Aged; Asthma; Bronchi; Bronchial Provocation Tests; Bronchitis; Erythromycin; Female; Forced | 1991 |
Analysis of expiratory pattern for monitoring bronchial obstruction in school-age children.
Topics: Adolescent; Airway Resistance; Asthma; Bronchial Provocation Tests; Child; Child, Preschool; Female; | 1991 |
Lung function and bronchial reactivity in asthmatics during exposure to volatile organic compounds.
Topics: Adult; Air Pollutants; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Female; Forced Expi | 1991 |
The influence of a family history of asthma and parental smoking on airway responsiveness in early infancy.
Topics: Asthma; Bronchial Provocation Tests; Bronchoconstriction; Female; Fetus; Forced Expiratory Flow Rate | 1991 |
Relationship of airway hyperresponsiveness to respiratory symptoms and diurnal peak flow variation in patients with obstructive lung disease. The Dutch CNSLD Study Group.
Topics: Adult; Asthma; Bronchial Provocation Tests; Bronchitis; Bronchoconstriction; Bronchodilator Agents; | 1991 |
Repeated provocation tests in asthmatic children for testing tachyphylaxis to histamine.
Topics: Adolescent; Asthma; Bronchi; Bronchial Provocation Tests; Child; Dose-Response Relationship, Drug; F | 1991 |
Acute effect of passive smoking on lung function and airway responsiveness in asthmatic children.
Topics: Adolescent; Airway Resistance; Asthma; Bronchial Provocation Tests; Child; Cotinine; Eye; Female; Fo | 1991 |
Refractoriness for ultrasonically nebulized distilled water and histamine after histamine challenge.
Topics: Adult; Asthma; Bronchi; Bronchial Provocation Tests; Female; Histamine; Humans; Male; Middle Aged; N | 1991 |
Histamine hyperresponsiveness of the extrathoracic airway in patients with asthmatic symptoms.
Topics: Asthma; Bronchial Provocation Tests; Female; Fiber Optic Technology; Histamine; Humans; Laryngoscopy | 1991 |
Selective breeding of two lines of guinea pigs differing in bronchial sensitivity to acetylcholine and histamine exposure.
Topics: Acetylcholine; Animals; Asthma; Breeding; Bronchi; Bronchial Provocation Tests; Female; Guinea Pigs; | 1991 |
Characteristics of bronchial hyperresponsiveness in chronic obstructive pulmonary disease and in asthma.
Topics: Asthma; Bronchi; Bronchial Provocation Tests; Dose-Response Relationship, Drug; Female; Forced Expir | 1991 |
Is it useful to distinguish between asthma and chronic obstructive pulmonary disease in respiratory epidemiology.
Topics: Asthma; Epidemiologic Methods; Forced Expiratory Volume; Histamine; Humans; Lung Diseases, Obstructi | 1991 |
Airway responsiveness in childhood as a predictor of the outcome of asthma in adulthood.
Topics: Adolescent; Airway Obstruction; Asthma; Child; Forced Expiratory Volume; Histamine; Humans; Predicti | 1991 |
Measurement of PC20 histamine with the use of two different nebulizers and measurement of FEV1 and PEF.
Topics: Adolescent; Adult; Asthma; Bronchial Provocation Tests; Forced Expiratory Volume; Histamine; Humans; | 1991 |
Effect of cold air on the bronchial response to inhaled histamine in patients with asthma.
Topics: Adult; Air; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Cold Temperature; Female; Hist | 1991 |
Immediate and late inflammatory responses to ragweed antigen challenge of the peripheral airways in allergic asthmatics. Cellular, mediator, and permeability changes.
Topics: Adult; Albumins; Antigens; Asthma; Bronchi; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Cell | 1991 |
Elevated bronchoalveolar lavage fluid histamine levels in allergic asthmatics are associated with increased airway obstruction.
Topics: Adolescent; Adult; Asthma; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Bronchoscopy; Female; | 1991 |
Nocturnal airflow obstruction, histamine, and the autonomic central nervous system in children with allergic asthma.
Topics: Adolescent; Airway Obstruction; Arrhythmia, Sinus; Asthma; Autonomic Nervous System; Child; Circadia | 1991 |
Epithelium-derived inhibitory factor in human bronchus.
Topics: Animals; Asthma; Biological Factors; Bronchi; Carbachol; Histamine; Humans; In Vitro Techniques; Ind | 1990 |
Bronchoconstriction of the asthmatic airway by inhaled and ingested propranolol.
Topics: Administration, Inhalation; Administration, Oral; Adolescent; Adult; Aged; Asthma; Bronchial Provoca | 1990 |
Anaphylactic challenge causes eosinophil accumulation in bronchoalveolar lavage fluid of guinea pigs. Modulation by betamethasone, phenidone, indomethacin, WEB 2086, and a novel antiallergy agent, SCH 37224.
Topics: Albumins; Anaphylaxis; Animals; Asthma; Azepines; Betamethasone; Bronchoalveolar Lavage Fluid; Cell | 1990 |
Effect of inhaled preservatives on asthmatic subjects. II. Benzalkonium chloride.
Topics: Adult; Asthma; Benzalkonium Compounds; Bronchial Provocation Tests; Cromolyn Sodium; Dose-Response R | 1990 |
Effects of histamine on alpha adrenergic receptor expression on the lymphocytes of normal and asthmatic subjects.
Topics: Asthma; Dihydroalprenolol; Dihydroergotoxine; Dose-Response Relationship, Drug; Histamine; Humans; M | 1990 |
Asthmatic airways have a disproportionate hyperresponsiveness to LTE4, as compared with normal airways, but not to LTC4, LTD4, methacholine, and histamine.
Topics: Adult; Airway Resistance; Asthma; Bronchoconstriction; Dose-Response Relationship, Drug; Female; His | 1990 |
Elevated levels of leukotriene C4 in bronchoalveolar lavage fluid from atopic asthmatics after endobronchial allergen challenge.
Topics: Adult; Allergens; Asthma; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Female; Histami | 1990 |
Airway hyperresponsiveness. Relevance of random population data to clinical usefulness.
Topics: Adult; Asthma; Bronchi; Bronchial Provocation Tests; Child; Histamine; Humans; Methacholine Chloride | 1990 |
The interrelationship among bronchial hyperresponsiveness, the diagnosis of asthma, and asthma symptoms.
Topics: Asthma; Bronchi; Child; Forced Expiratory Volume; Histamine; Humans; Random Allocation; Sensitivity | 1990 |
Enhanced reactive oxygen species metabolism of airspace cells and airway inflammation follow antigen challenge in human asthma.
Topics: Adult; Antigens; Asthma; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Eosinophils; Fem | 1990 |
It is children with atopic dermatitis who develop asthma more frequently if the mother smokes.
Topics: Adolescent; Asthma; Bronchial Provocation Tests; Child; Child, Preschool; Dermatitis, Atopic; Female | 1990 |
Bronchial responsiveness to histamine in infants and older children.
Topics: Adolescent; Asthma; Bronchi; Child; Child, Preschool; Forced Expiratory Flow Rates; Forced Expirator | 1990 |
Immunoglobulins and allergy mediators in bronchial asthma.
Topics: Adult; Asthma; Blood Coagulation; Histamine; Humans; Immunoglobulins; Random Allocation; Respiratory | 1990 |
The relationship between bronchial immunopathology and hyperresponsiveness in asthma.
Topics: Adolescent; Adult; Asthma; Bronchi; Bronchial Provocation Tests; Bronchial Spasm; Female; Forced Exp | 1990 |
[Airway smooth muscle responsiveness].
Topics: Acetylcholinesterase; Asthma; Autonomic Nervous System; Bronchi; Dinoprostone; Eosinophils; Histamin | 1990 |
The effect of fresh orange juice on bronchial hyperreactivity in asthmatic subjects.
Topics: Adolescent; Adult; Asthma; Beverages; Bronchial Provocation Tests; Bronchoconstriction; Citrus; Fema | 1990 |
Relationship between the airway response to inhaled sulfur dioxide, isocapnic hyperventilation, and histamine in asthmatic subjects.
Topics: Administration, Inhalation; Adolescent; Adult; Airway Resistance; Asthma; Bronchoconstriction; Femal | 1990 |
Exposure-response relationships in asthma caused by tetrachlorophthalic anhydride.
Topics: Adult; Air Pollutants, Occupational; Asthma; Bronchial Provocation Tests; Dose-Response Relationship | 1990 |
Abnormalities in airway smooth muscle in fatal asthma.
Topics: Acetylcholine; Adult; Asthma; Cholinergic Fibers; Electric Stimulation; Female; Histamine; Humans; I | 1990 |
The effect of inhaled 15-(s)-hydroxyeicosatetraenoic acid (15-HETE) on airway calibre and non-specific responsiveness in normal and asthmatic human subjects.
Topics: Administration, Inhalation; Adult; Asthma; Bronchi; Bronchial Provocation Tests; Female; Forced Expi | 1990 |
Responses of equine trachealis and lung parenchyma to methacholine, histamine, serotonin, prostanoids, and leukotrienes in vitro.
Topics: Animals; Asthma; Atropine; Disease Models, Animal; Histamine; Horses; In Vitro Techniques; Indometha | 1990 |
The relationship between conductance and functional residual capacity during drug-induced bronchoconstriction.
Topics: Acetylcholine; Adolescent; Adult; Airway Resistance; Asthma; Bronchi; Bronchial Provocation Tests; F | 1990 |
[Detection of bronchial hyperreactivity using the 1-step histamine test].
Topics: Airway Resistance; Asthma; Bronchial Provocation Tests; Histamine; Humans; Lung Diseases, Obstructiv | 1990 |
Diagnostic value of a glass fibre-based histamine analysis for allergy testing in children.
Topics: Asthma; Bronchial Provocation Tests; Child; Glass; Histamine; Humans; Immunologic Tests; Radioallerg | 1990 |
Does the outcome of the tidal breathing and dosimeter methods of assessing bronchial responsiveness in children with asthma depend on age?
Topics: Adolescent; Age Factors; Asthma; Bronchi; Bronchial Provocation Tests; Child; Child, Preschool; Fema | 1990 |
Variation of breath sound and airway caliber induced by histamine challenge.
Topics: Adult; Asthma; Female; Forced Expiratory Flow Rates; Forced Expiratory Volume; Histamine; Humans; Ma | 1990 |
[Experimental studies on treating anti-anaphylactic asthma with a qingfei bushen decoction].
Topics: Acetylcholine; Animals; Asthma; Drugs, Chinese Herbal; Female; Guinea Pigs; Histamine; Male; Passive | 1990 |
[Plasma and urinary histamine assay and the clinical significance].
Topics: Anaphylaxis; Asthma; Chromatography, High Pressure Liquid; Female; Gas Chromatography-Mass Spectrome | 1990 |
Antigen challenge induces pulmonary airway eosinophil accumulation and airway hyperreactivity in sensitized guinea-pigs: the effect of anti-asthma drugs.
Topics: Animals; Asthma; Blood Platelets; Bronchoalveolar Lavage Fluid; Dinoprost; Eosinophils; Guinea Pigs; | 1990 |
[Anamnesis, inhalation histamine test and 2 stress tests in the diagnosis of exercise-induced asthma].
Topics: Adolescent; Adult; Airway Resistance; Asthma; Asthma, Exercise-Induced; Bronchial Provocation Tests; | 1990 |
[Effect of histamine on bronchial hyperreactivity in sarcoidosis and other lung diseases].
Topics: Acetylcholine; Asthma; Bronchial Provocation Tests; Carbachol; Histamine; Humans; Lung Diseases; Res | 1990 |
[Patients with sarcoidosis frequently have bronchial hyperreactivity].
Topics: Adult; Asthma; Bronchial Provocation Tests; Female; Histamine; Humans; Lung Diseases; Male; Prospect | 1990 |
Evidence for elevated levels of histamine, prostaglandin D2, and other bronchoconstricting prostaglandins in the airways of subjects with mild asthma.
Topics: Adult; Asthma; Bronchoalveolar Lavage Fluid; Female; Gas Chromatography-Mass Spectrometry; Histamine | 1990 |
Increased leukocyte phospholipase A2 activity and plasma lysophosphatidylcholine levels in asthma and rhinitis and their relationship to airway sensitivity to histamine.
Topics: Adult; Asthma; Bronchial Provocation Tests; Female; Histamine; Humans; Leukocytes; Lysophosphatidylc | 1990 |
Lack of tachyphylaxis to histamine in both moderate and mild asthmatic subjects.
Topics: Asthma; Bronchi; Forced Expiratory Volume; Histamine; Humans; Tachyphylaxis | 1990 |
Products of neutrophils and eosinophils increase the responsiveness of human isolated bronchial tissue.
Topics: Asthma; Bronchi; Bronchial Spasm; Electric Stimulation; Eosinophils; Histamine; Humans; In Vitro Tec | 1990 |
Histamine bronchoprovocation tests in subjects with gastro-oesophageal reflux disease.
Topics: Adult; Asthma; Bronchial Provocation Tests; Forced Expiratory Flow Rates; Forced Expiratory Volume; | 1990 |
Ozone increases susceptibility to antigen inhalation in allergic dogs.
Topics: Acetylcholine; Aerosols; Airway Resistance; Animals; Antigens, Helminth; Ascaris; Asthma; Dogs; Fema | 1990 |
Skin reactivity to codeine and histamine during prolonged corticosteroid therapy.
Topics: Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Asthma; Codeine; Female; Histamine; Humans; | 1990 |
Tachyphylaxis to inhaled histamine in asthma: its significance and relationship to basal airway responsiveness.
Topics: Adolescent; Adult; Airway Resistance; Asthma; Bronchial Provocation Tests; Female; Histamine; Humans | 1990 |
The requirement for platelets in allergen-induced late asthmatic airway obstruction. Eosinophil infiltration and heightened airway responsiveness in allergic rabbits.
Topics: Allergens; Animals; Asthma; Blood Platelets; Bronchi; Bronchial Provocation Tests; Eosinophils; Guin | 1990 |
Inhibition of histamine release from basophil leucocytes of asthmatic patients treated with corticosteroids.
Topics: Adrenal Cortex Hormones; Asthma; Basophils; Bronchial Provocation Tests; Histamine; Histamine Releas | 1985 |
Bronchoalveolar mast cells in extrinsic asthma: a mechanism for the initiation of antigen specific bronchoconstriction.
Topics: Adult; Antibodies, Anti-Idiotypic; Asthma; Bronchoscopy; Cell Count; Constriction, Pathologic; Epito | 1985 |
[Cellular and humoral bases of allergic reactions].
Topics: Anaphylaxis; Antibody Formation; Asthma; Basophils; Biogenic Amines; Capillary Permeability; Complem | 1985 |
[Symposium II bronchoconstriction--pathophysiology and treatment--4. Sensitization and chemical mediator release].
Topics: Asthma; Basophils; Histamine; Histamine Release; Humans; Immunoglobulin E; Mast Cells | 1985 |
Bronchial hyper-reactivity in atopic patients during H2-receptor blocker treatment.
Topics: Asthma; Bronchi; Bronchial Provocation Tests; Cimetidine; Histamine; Histamine H2 Antagonists; Hista | 1986 |
Histamine-dependent allergy blood test. Clinical evaluation.
Topics: Allergens; Asthma; Histamine; Histamine Release; Humans; Hypersensitivity; Rhinitis, Allergic, Seaso | 1986 |
Changes of histaminopexy in patients with bronchial asthma and chronic urticaria after histaglobin administration.
Topics: Adult; Aged; Asthma; Blood Proteins; Drug Combinations; Female; gamma-Globulins; Histamine; Histamin | 1986 |
Histamine levels in bronchoalveolar lavage from patients with asthma, sarcoidosis, and idiopathic pulmonary fibrosis.
Topics: Adult; Asthma; Histamine; Histamine Release; Humans; Immunoglobulin G; Lung; Peptidyl-Dipeptidase A; | 1987 |
A new glass microfibre-based histamine analysis for allergy testing in children. Results compared with conventional leukocyte histamine release assay, skin prick test, bronchial provocation test and RAST.
Topics: Asthma; Bronchial Provocation Tests; Child; Female; Histamine; Histamine Release; Humans; Immunologi | 1987 |
Effects of mast cell stabilizers on a new bronchial asthma model using compound 48/80 in dogs.
Topics: Airway Resistance; Animals; Asthma; Blood Pressure; Chlorpheniramine; Cromolyn Sodium; Cyclohexaneca | 1987 |
Inhibition of antigen-induced contraction of guinea pig isolated tracheal muscle with 2-n-butyl-3-dimethylamino-5,6-methylenedioxy indene (MDI-A), indane (MDI-B) and 8-(diethylamino)octyl-3,4,5-trimethoxy benzoate hydrochloride (TMB-8).
Topics: Animals; Antigens; Asthma; Calcium Channel Blockers; Female; Gallic Acid; Guinea Pigs; Histamine; Hi | 1987 |
Effect of OKY-046, a new thromboxane A2 synthetase inhibitor, on experimental asthma in guinea pigs.
Topics: Acrylates; Animals; Asthma; Female; Guinea Pigs; Histamine; Histamine Release; Indomethacin; Lung; M | 1987 |
Eosinophils and mast cells in bronchoalveolar lavage in subjects with mild asthma. Relationship to bronchial hyperreactivity.
Topics: Adult; Asthma; Bronchi; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Cell Count; Eosin | 1988 |
Properties of human basophils isolated by fluorescence-activated cell sorting.
Topics: Antigens, Differentiation, B-Lymphocyte; Asthma; Basophils; Calcimycin; Calcium; Cell Separation; Fl | 1988 |
Effect of AA-861, a selective 5-lipoxygenase inhibitor, on models of allergy in several species.
Topics: Animals; Asthma; Benzoquinones; Calcimycin; Chromatography, High Pressure Liquid; Female; Guinea Pig | 1988 |
[Clinical study on asthma treated with transilast].
Topics: Adolescent; Adult; Animals; Asthma; Child; Female; Guinea Pigs; Histamine; Humans; Male; Middle Aged | 1988 |
Spontaneous histamine release and histamine content in normal subjects and subjects with asthma.
Topics: Adolescent; Adult; Asthma; Basophils; Calcium; Child; Histamine; Histamine Release; Humans; Magnesiu | 1989 |
Chronological relationships between mediator release and changes in airway dynamics during an ascaris response in sensitive cynomolgus monkeys.
Topics: Animals; Antigens, Helminth; Ascaris; Asthma; Dinoprost; Histamine; Histamine Release; Hydroxyeicosa | 1989 |
Effect of 8-hexyloxy-3-(1H-tetrazol-5-yl)-2H-chromen-2-one [KP-136] on experimental asthma: a comparison with disodium cromoglycate.
Topics: Animals; Antigens; Asthma; Capillary Permeability; Chromones; Cromolyn Sodium; Guinea Pigs; Histamin | 1989 |
[The changes in plasma histamine levels after a sulpyrin inhalation test in asthmatic patients].
Topics: Adult; Aminopyrine; Aspirin; Asthma; Bronchial Provocation Tests; Dipyrone; Female; Histamine; Hista | 1989 |
[Improvement of airway hyperreactivity in bronchial asthma patients with short disease duration treated with anti-allergic agents].
Topics: Adult; Asthma; Bronchi; Cromolyn Sodium; Drug Therapy, Combination; Female; Histamine; Humans; Ketot | 1989 |
The effect of smooth muscle relaxants working through different transduction mechanisms on the phorbol dibutyrate-induced contraction of the guinea-pig lung parenchymal strip: possible relevance for asthma.
Topics: Animals; Asthma; Enzyme Activation; Guinea Pigs; Histamine; In Vitro Techniques; Ion Channels; Lung; | 1989 |
[Asthmatic responses in allergic asthma, especially late asthmatic response].
Topics: Allergens; Animals; Asthma; Cromolyn Sodium; Histamine; Hydrocortisone; Hypersensitivity, Delayed; P | 1989 |
The effect of passive sensitisation of human bronchial smooth muscle on in vitro sensitivity to histamine.
Topics: Adult; Allergens; Asthma; Bronchi; Histamine; Humans; Hypersensitivity, Immediate; Immunization, Pas | 1989 |
Effect of a thromboxane receptor antagonist on PGD2- and allergen-induced bronchoconstriction.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adolescent; Adult; Animals; Asth | 1989 |
Appearance of allergen-induced increases in airway responsiveness only after repeated allergen inhalations in two subjects.
Topics: Adolescent; Adult; Allergens; Asthma; Bronchial Provocation Tests; Female; Forced Expiratory Volume; | 1989 |
The effect of histamine challenge on platelet count and platelet activation.
Topics: Adolescent; Adult; Asthma; beta-Thromboglobulin; Bronchial Spasm; Female; Histamine; Humans; Male; M | 1989 |
Rhinovirus upper respiratory infection increases airway hyperreactivity and late asthmatic reactions.
Topics: Adult; Asthma; Bronchial Provocation Tests; Cyclic AMP; Female; Histamine; Humans; Isoproterenol; Ma | 1989 |
Use of segmental airway lavage to obtain relevant mediators from the lungs of asthmatic and control subjects.
Topics: Adolescent; Adult; Asthma; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Bronchoscopes; | 1989 |
Bronchial hyperreactivity induced by parainfluenza 3 is partly prevented by atropine.
Topics: Animals; Asthma; Atropine; Bronchi; Guinea Pigs; Histamine; Male; Parainfluenza Virus 3, Human; Para | 1989 |
Leukocytes and mediators in bronchoalveolar lavage during allergen-induced late-phase asthmatic reactions.
Topics: Adolescent; Adult; Allergens; Asthma; Blood Proteins; Bronchial Provocation Tests; Bronchoalveolar L | 1989 |
Non-specific bronchial airway hyperreactivity and the diagnosis of asthma.
Topics: Adult; Asthma; Bronchial Provocation Tests; Forced Expiratory Volume; Histamine; Humans; Methacholin | 1989 |
Airway responsiveness to histamine and leukotriene E4 in subjects with aspirin-induced asthma.
Topics: Adult; Aspirin; Asthma; Bronchial Provocation Tests; Female; Histamine; Humans; Leukotriene B4; Male | 1989 |
[Role of plasma histamine and neutrophil chemotactic factor in exercise-induced asthma].
Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Chemotactic Factors; Female; Histamine; Histami | 1989 |
Azelastine inhibits agonist-induced electromechanical activity in canine tracheal muscle.
Topics: Acetylcholine; Animals; Asthma; Bronchodilator Agents; Dogs; Histamine; Histamine H1 Antagonists; Is | 1989 |
[Comparative evaluation of the effectiveness of different methods of prophylactic treatment for children with bronchial asthma].
Topics: Adjuvants, Immunologic; Adolescent; Asthma; Beclomethasone; Child; Child, Preschool; Cromolyn Sodium | 1985 |
Anti-asthmatic activity of newly synthesized calcium antagonists: 2-n-butyl-1 (N-methyl-n-[2-(N',N'-dimethylamino)ethyl]amino) -5,6-methylenedioxy-indene and -indane.
Topics: Animals; Asthma; Calcium; Calcium Channel Blockers; Female; Guinea Pigs; Histamine; In Vitro Techniq | 1989 |
[Application of HPLC to measurement of plasma histamine in bronchial asthma].
Topics: Adult; Aged; Asthma; Chromatography, High Pressure Liquid; Female; Histamine; Humans; Male; Middle A | 1989 |
[Biochemical changes in the airways after antigen inhalation challenge in asthma].
Topics: Animals; Arachidonic Acids; Asthma; Bronchial Provocation Tests; Guinea Pigs; Histamine; Humans; Mus | 1989 |
Circadian change in bronchial responsiveness and airflow obstruction in asthmatic children.
Topics: Adolescent; Airway Resistance; Asthma; Bronchi; Bronchial Provocation Tests; Child; Circadian Rhythm | 1989 |
Prevalence of asthma, atopy, and bronchial hyperreactivity in bronchiectasis: a controlled study.
Topics: Adult; Asthma; Bronchial Provocation Tests; Bronchiectasis; Female; Histamine; Humans; Hypersensitiv | 1989 |
The repeatability and validity of respiratory resistance measured by the forced oscillation technique.
Topics: Adult; Airway Resistance; Asthma; Bronchial Provocation Tests; Female; Forced Expiratory Volume; His | 1989 |
A comparison of airway responsiveness in smokers with chronic bronchitis and in asthmatic subjects.
Topics: Adult; Asthma; Bronchial Provocation Tests; Bronchitis; Chronic Disease; Female; Forced Expiratory V | 1989 |
A muscarinic agonist inhibits reflex bronchoconstriction in normal but not in asthmatic subjects.
Topics: Adult; Airway Resistance; Asthma; Bronchi; Female; Histamine; Humans; Male; Pilocarpine; Receptors, | 1989 |
Airways responsiveness determined by consecutive histamine challenges in asymptomatic asthmatics.
Topics: Adult; Aerosols; Asthma; Bronchi; Bronchial Provocation Tests; Forced Expiratory Volume; Histamine; | 1989 |
Clinical significance of airway responsiveness in children of low birthweight.
Topics: Administration, Inhalation; Asthma; Bronchial Provocation Tests; Child; Cohort Studies; Follow-Up St | 1989 |
The influence of the calcium channel antagonist verapamil on histamine release from target cells.
Topics: Asthma; Basophils; Calcium Channel Blockers; Histamine; Humans; Verapamil | 1989 |
The effect of immunotherapy on the in vitro productions of histamine, prostaglandin E2 and leukotriene C4 in asthmatic children.
Topics: Animals; Asthma; Child; Dinoprostone; Female; Histamine; Humans; Immunotherapy; Male; Mites; SRS-A | 1989 |
[The relationship between bronchial hypersensitivity and the prognosis of bronchial asthma].
Topics: Acetylcholine; Adolescent; Asthma; Asthma, Exercise-Induced; Bronchi; Bronchial Provocation Tests; C | 1989 |
Flexible fiberoptic bronchoscopy does not alter airway responsiveness.
Topics: Adult; Asthma; Atropine; Bronchi; Bronchial Provocation Tests; Bronchoscopy; Fiber Optic Technology; | 1989 |
Effect of bronchial challenge on breathing patterns and arterial oxygenation in stable asthma.
Topics: Adolescent; Adult; Asthma; Bronchial Provocation Tests; Forced Expiratory Volume; Histamine; Humans; | 1989 |
Significant changes in nonspecific bronchial responsiveness after isolated immediate bronchospecific reactions caused by isocyanates but not after a late reaction caused by plicatic acid.
Topics: Adult; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Cyanates; Forced Expiratory Volume; His | 1989 |
Spectrum of prostanoid release after bronchoalveolar allergen challenge in atopic asthmatics and in control groups. An alteration in the ratio of bronchoconstrictive to bronchoprotective mediators.
Topics: Adolescent; Adult; Allergens; Asthma; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; His | 1989 |
What symptoms predict the bronchial response to histamine? Evaluation in a community survey of the bronchial symptoms questionnaire (1984) of the International Union Against Tuberculosis and Lung Disease.
Topics: Adult; Age Factors; Asthma; Bronchial Provocation Tests; Data Interpretation, Statistical; England; | 1989 |
The distribution of bronchial responsiveness to histamine in symptomatic and in asymptomatic subjects. A population-based analysis of various indices of responsiveness.
Topics: Adolescent; Adult; Asthma; Bronchial Provocation Tests; Female; Forced Expiratory Volume; Histamine; | 1989 |
[Correlation of "nonspecific" hyper-reactivity of the airways with central and peripheral disorders of lung function].
Topics: Airway Resistance; Asthma; Bronchi; Bronchial Provocation Tests; Flour; Histamine; Humans; Lung Volu | 1989 |
Response localization of the pharmacological agents histamine and salbutamol along the respiratory system by forced oscillations in asthmatic subjects.
Topics: Adult; Airway Resistance; Albuterol; Asthma; Bronchial Provocation Tests; Female; Forced Expiratory | 1989 |
Airway responses to hypertonic saline, exercise and histamine challenges in bronchial asthma.
Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Exercise; Forced Expiratory Volume; Histamine; | 1989 |
Role of platelet activating factor in the endotoxin induced tracheal hyperreactivity to histamine in the guinea pig.
Topics: Animals; Asthma; Endotoxins; Guinea Pigs; Histamine; Male; Platelet Activating Factor; Trachea | 1989 |
Histamine determination in the blood during the immediate asthmatic response (IAR).
Topics: Asthma; Histamine; Humans | 1989 |
Seasonal variability of exercise-induced asthma especially outdoors. Effect of birch pollen allergy.
Topics: Adult; Asthma; Asthma, Exercise-Induced; Cold Temperature; Exercise Test; Forced Expiratory Volume; | 1989 |
[Comparison of the effect of 2 methods of histamine administration on the bronchomotor response in asthmatics].
Topics: Adult; Aerosols; Asthma; Bronchial Provocation Tests; Female; Histamine; Humans; Male; Nebulizers an | 1989 |
[The effect of exercise on the content of biogenic amines and acetylcholine of the blood in bronchial asthma patients].
Topics: Acetylcholine; Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Biogenic Amines; Catecholamines; | 1989 |
[Mast-cell mechanism of the pathogenesis of bronchial asthma and peroxidation of membrane lipids].
Topics: Adult; Animals; Asthma; Bronchitis; Cell Membrane; Histamine; Humans; Infections; Lipid Peroxidation | 1989 |
Bronchial reactivities in guinea pigs to acetylcholine or histamine exposure.
Topics: Acetylcholine; Age Factors; Animals; Asthma; Bronchi; Bronchial Provocation Tests; Disease Models, A | 1989 |
Development of chronic airway hyperresponsiveness in ragweed-sensitized dogs.
Topics: Airway Resistance; Animals; Animals, Newborn; Asthma; Bronchoalveolar Lavage Fluid; Chronic Disease; | 1989 |
Expression of results of histamine challenge.
Topics: Adolescent; Analysis of Variance; Asthma; Bronchial Provocation Tests; Child; Forced Expiratory Volu | 1989 |
Comparison of the effects of cimetidine and ranitidine in histamine provocation tests in atopic asthma.
Topics: Asthma; Bronchi; Bronchial Provocation Tests; Cimetidine; Histamine; Humans; Ranitidine; Receptors, | 1989 |
Changes of allergen-specific antibodies, circulating immune complexes and restoration of polymorphonuclear leukocyte function after hyposensitization.
Topics: Adolescent; Allergens; Antigen-Antibody Complex; Asthma; Child; Child, Preschool; Desensitization, I | 1989 |
Bronchial provocation testing.
Topics: Allergens; Asthma; Bronchial Provocation Tests; Dose-Response Relationship, Immunologic; Histamine; | 1989 |
Levomepromazine (Nozinan) reduces nonspecific bronchial hyperreactivity in asthmatics.
Topics: Adult; Antazoline; Asthma; Bronchi; Bronchial Provocation Tests; Forced Expiratory Volume; Histamine | 1989 |
Inhibition by histamine of platelet-activating-factor-induced neutrophil chemotaxis in bronchial asthma.
Topics: Asthma; Chemotaxis, Leukocyte; Histamine; Humans; In Vitro Techniques; Neutrophils; Platelet Activat | 1989 |
Human isolated bronchial muscle preparations from asthmatic patients: effects of indomethacin and contractile agonists.
Topics: Acetylcholine; Asthma; Bronchi; Dinoprost; Dinoprostone; Histamine; Humans; In Vitro Techniques; Ind | 1989 |
Ether does not antagonize bronchoconstriction caused by acetylcholine, histamine, or phenylephrine.
Topics: Acetylcholine; Animals; Asthma; Bronchi; Constriction, Pathologic; Ether; Ethyl Ethers; Histamine; I | 1989 |
Localization of the site of the bronchoconstrictor effects of leukotriene C4 compared with that of histamine in asthmatic subjects.
Topics: Administration, Inhalation; Adult; Aerosols; Asthma; Bronchi; Constriction; Female; Histamine; Human | 1989 |
Clinical significance of nonspecific bronchial hyperresponsiveness in asthma.
Topics: Adolescent; Adult; Airway Resistance; Asthma; Bronchi; Bronchial Provocation Tests; Bronchial Spasm; | 1989 |
Passive smoking by asthmatics: its greater effect on boys than on girls and on older than on younger children.
Topics: Adolescent; Age Factors; Asthma; Bronchial Provocation Tests; Child; Child, Preschool; Female; Force | 1989 |
[Biologically active substance levels in exhaled air from patients with pre-asthma and bronchial asthma].
Topics: Acetylcholine; Adolescent; Adult; Asthma; Breath Tests; Bronchi; Bronchial Spasm; Histamine; Humans; | 1989 |
Prevalence and predictors of bronchial hyperresponsiveness in children aged 7-16 years.
Topics: Adolescent; Asthma; Bronchi; Child; Cross-Sectional Studies; Denmark; Female; Histamine; Humans; Imm | 1989 |
A prospective study of bronchial hyperresponsiveness and respiratory symptoms in a population of Australian schoolchildren.
Topics: Adolescent; Age Factors; Asthma; Australia; Child; Cross-Sectional Studies; Dose-Response Relationsh | 1989 |
Pulmonary gas exchange during histamine-induced bronchoconstriction in asthmatic subjects.
Topics: Adult; Asthma; Bronchial Provocation Tests; Female; Forced Expiratory Volume; Histamine; Humans; Mal | 1989 |
Childhood asthma following hospitalization with acute viral bronchiolitis in infancy.
Topics: Acute Disease; Asthma; Bronchial Provocation Tests; Bronchiolitis, Viral; Child; Child, Hospitalized | 1989 |
Bronchial hyperresponsiveness in asthmatic children. Correlation with macrophages and eosinophils in broncholavage fluid.
Topics: Asthma; Bronchi; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Bronchoscopy; Cell Count | 1989 |
Esophageal acid perfusion, airway function, and symptoms in asthmatic patients with marked bronchial hyperreactivity.
Topics: Aged; Asthma; Bronchi; Bronchial Provocation Tests; Bronchial Spasm; Circadian Rhythm; Esophagus; Fe | 1989 |
Depression of polymorphonuclear chemotaxis and T-lymphocyte proliferation following histamine inhalation in man.
Topics: Adult; Asthma; Bronchial Provocation Tests; Cell Division; Chemotaxis, Leukocyte; Depression, Chemic | 1989 |
The prevalence of the early and late asthmatic reaction after exercise in patients with intrinsic and extrinsic asthma.
Topics: Adolescent; Adult; Aged; Asthma; Asthma, Exercise-Induced; Child; Female; Forced Expiratory Volume; | 1989 |
Prognosis of asthma from childhood to adulthood.
Topics: Adolescent; Aging; Asthma; Child; Female; Forced Expiratory Volume; Histamine; Humans; Longitudinal | 1989 |
Bronchial hyperreactivity in patients who cough after receiving angiotensin converting enzyme inhibitors.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Asthma; Bronchi; Bronchial Provocation Tests; | 1988 |
Comparative contractile responses to sulfidopeptide leukotrienes in normal and asthmatic human subjects.
Topics: Airway Obstruction; Asthma; Bronchi; Bronchial Provocation Tests; Forced Expiratory Volume; Histamin | 1988 |
Humoral and cellular components in inflammation: hyper-reactivity and decreased feed-back inhibition of asthmatic neutrophils.
Topics: Asthma; Histamine; Humans; Neutrophils; Respiratory Hypersensitivity; Superoxides | 1988 |
The relative responsiveness to inhaled leukotriene E4, methacholine and histamine in normal and asthmatic subjects.
Topics: Administration, Inhalation; Adolescent; Adult; Asthma; Bronchi; Female; Histamine; Humans; Leukotrie | 1988 |
Relationship between bronchial airway responsiveness and clinical severity of asthma.
Topics: Adult; Airway Resistance; Asthma; Bronchi; Bronchial Provocation Tests; Bronchodilator Agents; Cold | 1988 |
Astemizole and other H1-antihistaminic drug treatment of asthma.
Topics: Astemizole; Asthma; Benzimidazoles; Bronchial Provocation Tests; Bronchial Spasm; Histamine; Histami | 1985 |
Nocturnal asthma and timing of treatment.
Topics: Adrenergic beta-Antagonists; Airway Resistance; Aminophylline; Asthma; Bronchi; Circadian Rhythm; De | 1985 |
In vitro responsiveness of human asthmatic bronchus to carbachol, histamine, beta-adrenoceptor agonists and theophylline.
Topics: Adolescent; Adrenergic beta-Agonists; Adult; Aged; Airway Resistance; Asthma; Bronchi; Carbachol; Ch | 1986 |
Clinical pharmacodynamics of antihistamines.
Topics: Animals; Asthma; Brain; Bronchial Provocation Tests; Cetirizine; Drug Evaluation; Electroencephalogr | 1987 |
Effect of oral terfenadine on the bronchoconstrictor response to inhaled histamine and adenosine 5'-monophosphate in non-atopic asthma.
Topics: Adenosine Monophosphate; Administration, Inhalation; Administration, Oral; Adult; Aged; Asthma; Benz | 1987 |
Pharmacodynamic aspects of chlorpheniramine-induced bronchodilatation.
Topics: Acetylcholine; Adult; Asthma; Bronchi; Bronchodilator Agents; Chlorpheniramine; Histamine; Histamine | 1988 |
Effect of terfenadine on the response to exercise and cold air in asthma.
Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Benzhydryl Compounds; Cold Temperature; Forced | 1988 |
Azelastine inhibits bronchial hyperreactivity to acetylcholine in guinea pigs.
Topics: Acetylcholine; Animals; Antigens; Asthma; Bronchi; Guinea Pigs; Histamine; Histamine H1 Antagonists; | 1988 |
Effect of inhaled leukotriene C4 on cardiopulmonary function.
Topics: Administration, Inhalation; Adult; Aged; Airway Resistance; Asthma; Female; Forced Expiratory Flow R | 1989 |
Falls in peripheral eosinophil counts parallel the late asthmatic response.
Topics: Adult; Allergens; Asthma; Bronchial Provocation Tests; Circadian Rhythm; Eosinophils; Female; Forced | 1989 |
Interaction of inhaled LTC4 with histamine and PGD2 on airway caliber in asthma.
Topics: Administration, Inhalation; Adult; Asthma; Bronchial Provocation Tests; Drug Interactions; Female; F | 1989 |
Expression of complement receptors type 1 (CR1) and type 3 (CR3) on circulating granulocytes in experimentally provoked asthma.
Topics: Adolescent; Adult; Antigens; Asthma; Asthma, Exercise-Induced; Female; Granulocytes; Histamine; Huma | 1989 |
The reproducibility and agreement of three indices of airway responsiveness to histamine in asthmatic children.
Topics: Adolescent; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Child; Dose-Response Relationship, | 1989 |
Refractory period following bronchoconstriction provoked by histamine in asthmatic subjects.
Topics: Adult; Airway Resistance; Asthma; Bronchi; Bronchial Provocation Tests; Female; Forced Expiratory Vo | 1989 |
Total respiratory resistance and reactance as a measurement of response to bronchial challenge with histamine.
Topics: Adolescent; Adult; Airway Resistance; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Female; | 1989 |
Platelet activation in allergic asthma.
Topics: Adenosine Triphosphate; Asthma; beta-Thromboglobulin; Blood Platelets; Collagen; Dust; Histamine; Hu | 1985 |
Effects of inhaled 9 alpha, 11 beta-prostaglandin F2 on airway function in man.
Topics: Adult; Airway Resistance; Asthma; Dinoprost; Forced Expiratory Volume; Histamine; Humans; Male; Maxi | 1987 |
Propranolol inhalation challenge in relation to histamine response in children with asthma.
Topics: Adolescent; Airway Resistance; Asthma; Bronchial Provocation Tests; Child; Female; Forced Expiratory | 1988 |
The relationship between bronchial responsiveness to methacholine and bronchial responsiveness to histamine in asthmatic subjects.
Topics: Adult; Asthma; Bronchi; Female; Histamine; Humans; Male; Methacholine Compounds; Middle Aged | 1988 |
Adenosine-induced bronchoconstriction in asthma: role of mast cell-mediator release.
Topics: Adenosine; Adult; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Chemotactic Factors; Cromoly | 1985 |
Reduced adenylate cyclase responsiveness to histamine in lymphocyte membranes of allergic asthmatic patients after allergen challenge.
Topics: Adenylyl Cyclases; Adult; Asthma; Bronchial Provocation Tests; Cell Membrane; Cyclic AMP; Female; Hi | 1985 |
[Polymyxin B sulfate-induced non-specific bronchial provocation in bronchial asthma and chronic bronchitis].
Topics: Adult; Asthma; Bronchial Provocation Tests; Bronchitis; Chronic Disease; Histamine; Humans; Male; Po | 1985 |
Adenosine-induced bronchoconstriction in asthma. Role of parasympathetic stimulation and adrenergic inhibition.
Topics: Adenosine; Adult; Asthma; Bronchi; Bronchial Provocation Tests; Constriction, Pathologic; Female; Hi | 1985 |
[Acquisition of beta-adrenergic blockade by repeated induction of airway anaphylaxis: changes in beta-adrenergic receptor levels in lung homogenates and beta-adrenergic response in tracheal muscles in guinea pigs with experimental asthma].
Topics: Animals; Asthma; Epinephrine; Guinea Pigs; Histamine; Isoproterenol; Lung; Male; Norepinephrine; Rec | 1985 |
Exacerbations of asthma in adults during experimental rhinovirus infection.
Topics: Adult; Asthma; Bronchi; Bronchoscopy; Common Cold; Female; Histamine; Humans; Lung; Male; Respirator | 1985 |
[Mechanism of action of euphylline in atopic bronchial asthma in children].
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Aminophylline; Asthma; Bronchial Spasm; Child; Cyclic AMP; Cycl | 1985 |
The mast cell and theophylline in asthma.
Topics: Adenosine Triphosphate; Asthma; Chemotactic Factors; Chondroitin Sulfates; Cyclic AMP; Heparin; Hist | 1985 |
[Studies on changes in histamine levels in the blood of infants and children. Part 7. The time studies of histamine, lipoxygenase metabolites, thromboxe B2 and cyclic AMP release from human platelets and leucocytes on treadmill exercise in asthmatic child
Topics: Adolescent; Age Factors; Asthma; Asthma, Exercise-Induced; Blood Platelets; Child; Cyclic AMP; Exerc | 1985 |
Influence of the epithelium on responsiveness of guinea-pig isolated trachea to contractile and relaxant agonists.
Topics: Acetylcholine; Animals; Asthma; Autoradiography; Carbachol; Cimetidine; Colforsin; Dose-Response Rel | 1986 |
[Disorders of cholinergic regulation in patients with bronchial asthma].
Topics: Acid Phosphatase; Acute Disease; Adult; Aged; Asthma; Cholinesterases; Cyclic GMP; Female; Histamine | 1986 |
Airway responses to inhaled ouabain in subjects with and without asthma.
Topics: Adult; Aerosols; Asthma; Bronchi; Bronchial Provocation Tests; Female; Histamine; Humans; Male; Maxi | 1986 |
Specific immunological modulation of lymphocyte adenylate cyclase in asthmatic patients after allergenic bronchial provocation.
Topics: Adenylyl Cyclases; Adolescent; Adult; Allergens; Asthma; Bronchial Provocation Tests; Female; Guanyl | 1986 |
Bronchoconstrictor effects of leukotriene E4 in normal and asthmatic subjects.
Topics: Aerosols; Asthma; Bronchial Spasm; Dose-Response Relationship, Drug; Female; Forced Expiratory Volum | 1987 |
[Chemical mediators in exercise-induced asthma].
Topics: Adolescent; Asthma; Asthma, Exercise-Induced; Body Temperature Regulation; Body Water; Child; Female | 1987 |
Regulation of the beta-receptor-adenylate cyclase system in lymphocytes of allergic patients with asthma: possible role for protein kinase C in allergen-induced nonspecific refractoriness of adenylate cyclase.
Topics: Adenylyl Cyclases; ADP-Ribosylation Factors; Adult; Asthma; Bronchial Provocation Tests; Carrier Pro | 1987 |
Provocation dose and discriminant analysis in histamine bronchoprovocation. Are the current predictive data satisfactory?
Topics: Adolescent; Adult; Asthma; Bronchial Provocation Tests; Diagnostic Errors; Forced Expiratory Volume; | 1988 |
Evaluation of bronchial responsiveness by pharmacological challenges in asthma. Inhaled propranolol in comparison with histamine and methacholine.
Topics: Adolescent; Adult; Asthma; Bronchi; Bronchial Provocation Tests; Child; Histamine; Humans; Male; Met | 1988 |
[Bronchial hyperresponsiveness in aspirin induced asthma].
Topics: Adult; Aged; Aspirin; Asthma; Bronchial Provocation Tests; Dinoprost; Female; Histamine; Humans; Mal | 1988 |
Response to inhaled histamine and 24 hour sodium excretion.
Topics: Adolescent; Adult; Asthma; Bronchial Provocation Tests; Cross-Sectional Studies; England; Histamine; | 1986 |
Alternative modes of action of sodium cromoglycate.
Topics: Animals; Antigens; Ascaris; Asthma; Bronchi; Cromolyn Sodium; Dogs; Histamine; Humans; Mast Cells | 1986 |
Enhanced IgE-dependent basophil histamine release and airway reactivity in asthma.
Topics: Adult; Antibodies, Anti-Idiotypic; Asthma; Basophils; Bronchi; Bronchial Provocation Tests; Calcimyc | 1986 |
[Protective effect of nifedipine on histamine-induced bronchial spasm in patients responding and not responding to Intal treatment].
Topics: Adult; Asthma; Bronchial Spasm; Cromolyn Sodium; Female; Histamine; Humans; Male; Nifedipine | 1986 |
The function and properties of human lung mast cells.
Topics: Animals; Asthma; Bronchi; Cromolyn Sodium; Cytological Techniques; Histamine; Humans; Immunization, | 1986 |
Histamine binding proteins identified in healthy subjects and asthmatic patients.
Topics: Adult; Asthma; Blood Proteins; Carrier Proteins; Chromatography, Affinity; Female; Histamine; Humans | 1986 |
[Blood basophil histamine and immunoglobulin levels in children with bronchial asthma treated with Pollinex].
Topics: Adolescent; Allergens; Antigens, Plant; Asthma; Basophils; Child; Desensitization, Immunologic; Drug | 1987 |
Effect of dietary salt on bronchial reactivity to histamine in asthma.
Topics: Adolescent; Adult; Asthma; Bronchi; Bronchial Provocation Tests; Female; Forced Expiratory Volume; H | 1988 |
Lipoxygenase metabolites as mediators of platelet activating factor-induced increased airways responsiveness to histamine in the guinea-pig.
Topics: Animals; Asthma; Guinea Pigs; Histamine; In Vitro Techniques; Leukotriene Antagonists; Leukotrienes; | 1988 |
Effect of dietary salt on bronchial reactivity to histamine in asthma.
Topics: Asthma; Bronchi; Histamine; Humans; Sodium, Dietary | 1988 |
Chemical mediator in exercise-induced asthma and exercise-induced late asthmatic responses.
Topics: Adolescent; Asthma; Asthma, Exercise-Induced; Chemotaxis, Leukocyte; Child; Female; Forced Expirator | 1987 |
A role for inflammatory mediators in airway hyper-responsiveness.
Topics: Animals; Asthma; Bronchi; Bronchial Spasm; Carbachol; Dinoprost; Histamine; Muscle, Smooth; Prostagl | 1988 |
Passive smoking and the seasonal difference of severity of asthma in children.
Topics: Adolescent; Asthma; Bronchial Provocation Tests; Child; Female; Forced Expiratory Volume; Histamine; | 1988 |
Acute exposure to sawdust does not alter airway calibre and responsiveness to histamine in asthmatic subjects.
Topics: Adult; Aged; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Environmental Pollutants; Female; | 1988 |
Eosinophilic leucocytes and arylsulfatase activity in bronchoalveolar lavage fluid of patients with bronchial asthma.
Topics: Adult; Arylsulfatases; Asthma; Dimercaprol; Eosinophils; Histamine; Humans; Hypersensitivity; Immuno | 1988 |
[Bronchial hypersensitivity in infants and toddlers].
Topics: Asthma; Bronchial Provocation Tests; Child, Preschool; Dermatitis, Atopic; Female; Histamine; Humans | 1988 |
The use of sequential doses of inhaled histamine in the measurement of bronchial responsiveness: cumulative effect and distortion produced by shortening the test protocol.
Topics: Administration, Inhalation; Adolescent; Adult; Aged; Asthma; Bronchial Provocation Tests; Dose-Respo | 1988 |
Plasma elevations of histamine and a prostaglandin metabolite in acute asthma.
Topics: Acute Disease; Adolescent; Asthma; Child; Child, Preschool; Dinoprost; Histamine; Hospitalization; H | 1988 |
A comparison of mediator and catecholamine release between exercise- and hypertonic saline-induced asthma.
Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Catecholamines; Chemotaxis, Leukocyte; Female; | 1988 |
Histamine bronchoconstriction reduces airway responsiveness in asthmatic subjects.
Topics: Acetylcholine; Adolescent; Adult; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Female; Hist | 1988 |
Exercise refractoriness after histamine inhalation in asthmatic subjects.
Topics: Administration, Inhalation; Asthma; Bronchial Spasm; Exercise; Forced Expiratory Volume; Histamine; | 1988 |
Reflex decrease of histamine-induced bronchoconstriction after laryngeal stimulation in asthmatic patients.
Topics: Administration, Inhalation; Adult; Asthma; Autonomic Nervous System; Bronchi; Epinephrine; Female; H | 1988 |
[Distilled water inhalation challenge in asthmatic children].
Topics: Acetates; Acetic Acid; Administration, Inhalation; Adolescent; Asthma; Bronchi; Bronchial Provocatio | 1988 |
[The changes in bronchial hypersensitivity in preschool children with bronchial asthma].
Topics: Asthma; Bronchi; Bronchial Provocation Tests; Child; Child, Preschool; Female; Histamine; Humans; Ma | 1988 |
Relevance of histamine to the anaesthetist.
Topics: Anesthesia; Asthma; Cardiovascular Diseases; Central Nervous System Diseases; Histamine; Humans; Str | 1988 |
Dose-related effect of inhaled magnesium sulfate on histamine bronchial challenge in asthmatics.
Topics: Adolescent; Adult; Asthma; Bronchial Provocation Tests; Child; Dose-Response Relationship, Drug; Fem | 1988 |
Changes in neural drive (EMGd) and neuromuscular coupling during histamine-induced bronchoconstriction in patients with asthma.
Topics: Adult; Asthma; Bronchi; Diaphragm; Electromyography; Female; Forced Expiratory Volume; Histamine; Hu | 1988 |
[Humoral and cellular components in bronchoalveolar lavage fluid of atopic asthmatics].
Topics: Antibody Formation; Arylsulfatases; Asthma; Bronchoalveolar Lavage Fluid; Eosinophils; Female; Hista | 1988 |
Usefulness and safety of pharmacologic bronchoprovocation challenge in evaluating patients with normal spirometric tests who are suspected of having asthma.
Topics: Asthma; Bronchial Provocation Tests; Bronchial Spasm; Histamine; Humans; Methacholine Chloride; Meth | 1988 |
Analysis of bronchomotor tone in anesthetized guinea pigs by impedance plethysmography: a simple method for the evaluation of bronchodilator action.
Topics: Anesthesia; Animals; Asthma; Blood Pressure; Bronchi; Bronchodilator Agents; Dogs; Fenoterol; Guinea | 1988 |
Inhalation methods for the study of airway responsiveness.
Topics: Airway Obstruction; Allergens; Asthma; Bronchial Provocation Tests; Cold Temperature; Histamine; Hum | 1987 |
In vitro responses of airways from an asthmatic patient.
Topics: Adult; Asthma; Bronchi; Electric Stimulation; Histamine; Humans; In Vitro Techniques; Male; Methacho | 1987 |
Prevalence and characteristics of late asthmatic responses to exercise.
Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Bronchial Provocation Tests; Chemotaxis, Leukoc | 1987 |
Plasma histamine after methacholine, allergen, and aspirin challenges.
Topics: Adult; Antigens; Aspirin; Asthma; Female; Histamine; Humans; Hypersensitivity, Immediate; Lignans; M | 1987 |
Circulating concentrations of histamine, neutrophil chemotactic activity, and catecholamines during the refractory period in exercise-induced asthma.
Topics: Adult; Asthma; Asthma, Exercise-Induced; Catecholamines; Chemotactic Factors; Chemotaxis, Leukocyte; | 1988 |
Natural killer cell activity in specific and non-specific bronchial challenge.
Topics: Adult; Antigens; Asthma; Bronchial Provocation Tests; Female; Histamine; Humans; Killer Cells, Natur | 1988 |
Airway hyperreactivity in tropical pulmonary eosinophilia.
Topics: Adolescent; Adult; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Female; Histamine; Humans; | 1988 |
Airway responsiveness to histamine in patients refractory to repeated exercise.
Topics: Adult; Asthma; Asthma, Exercise-Induced; Bronchial Provocation Tests; Exercise Test; Female; Forced | 1988 |
Bronchoconstriction due to exercise combined with cold air inhalation does not generally influence bronchial responsiveness to inhaled histamine in asthmatic subjects.
Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Bronchi; Bronchial Provocation Tests; Cold Temp | 1988 |
Seasonal variation in bronchial reactivity in a community population.
Topics: Adolescent; Adult; Aged; Asthma; Bronchi; Female; Histamine; Humans; Hypersensitivity, Immediate; Ma | 1988 |
Regional differences in the mechanical properties of rabbit airway smooth muscle.
Topics: Acetylcholine; Animals; Asthma; Bronchi; Histamine; In Vitro Techniques; Indomethacin; Male; Muscle | 1988 |
Kinetics of the recovery from bronchial obstruction due to hyperventilation of cold air in asthmatic subjects.
Topics: Adult; Airway Resistance; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Cold Temperature; Fe | 1988 |
[The blood histamine level of patients with bronchial asthma and their skin vascular reaction to histamine].
Topics: Adolescent; Adult; Aged; Asthma; Dose-Response Relationship, Drug; Female; Histamine; Humans; Iontop | 1988 |
Airway responsiveness in low birthweight children and their mothers.
Topics: Asthma; Bronchi; Bronchial Provocation Tests; Female; Histamine; Humans; Infant, Low Birth Weight; I | 1988 |
[Testing bronchial reactivity with histamine].
Topics: Aerosols; Asthma; Bronchial Provocation Tests; Histamine; Humans; Respiratory Hypersensitivity | 1987 |
[Investigations of seasonal variation of bronchial hypersensitivity in asthmatic children].
Topics: Acetylcholine; Asthma; Asthma, Exercise-Induced; Bronchial Provocation Tests; Child; Female; Histami | 1987 |
[Bronchial responsiveness to inhaled leukotriene D4 in bronchial asthma. Part. 1. Comparison of the bronchial responsiveness of asthmatic patients to leukotriene D4, acetylcholine and histamine].
Topics: Acetylcholine; Administration, Inhalation; Adolescent; Adult; Aged; Asthma; Bronchi; Female; Histami | 1987 |
Bronchial responsiveness to histamine after repeated exercise-induced bronchospasm.
Topics: Adult; Airway Resistance; Asthma; Asthma, Exercise-Induced; Bronchi; Bronchial Provocation Tests; Br | 1987 |
The effect of cigarette withdrawal on asthmatics who smoke.
Topics: Adult; Airway Resistance; Asthma; Bronchi; Female; Histamine; Humans; Male; Middle Aged; Smoking; Su | 1987 |
Influence of asthmatic and rhinitic symptomatology duration on bronchial responsiveness to histamine.
Topics: Adolescent; Adult; Asthma; Bronchi; Child; Histamine; Humans; Middle Aged; Rhinitis; Time Factors | 1987 |
Reproducibility of histamine inhalation in asthmatics.
Topics: Adult; Aerosols; Asthma; Bronchial Provocation Tests; Drug Administration Schedule; Forced Expirator | 1986 |
Histamine challenge in asthmatics at 07.00-12.00-17.00 and 22.00 h.
Topics: Adult; Aerosols; Asthma; Bronchial Provocation Tests; Drug Administration Schedule; Forced Expirator | 1986 |
Regional V/Q changes in asthmatics after histamine inhalation.
Topics: Adult; Asthma; Bronchial Provocation Tests; Histamine; Humans; Lung; Peak Expiratory Flow Rate; Radi | 1986 |
The role of microvascular permeability in the pathogenesis of asthma.
Topics: Animals; Asthma; Bronchi; Capillary Permeability; Exudates and Transudates; Histamine; Humans; Infla | 1986 |
9 alpha,11 beta-prostaglandin F2, a novel metabolite of prostaglandin D2 is a potent contractile agonist of human and guinea pig airways.
Topics: Adult; Airway Resistance; Animals; Asthma; Bronchi; Dinoprost; Forced Expiratory Volume; Guinea Pigs | 1987 |
[The bronchial provocation test with histamine in the diagnosis and evaluation of the severity of asthma].
Topics: Adolescent; Adult; Asthma; Bronchial Provocation Tests; Histamine; Humans | 1986 |
Bronchial histamine challenge in the diagnosis of asthma. The predictive value of changes in airway resistance determined by the interrupter method.
Topics: Adolescent; Adult; Aged; Airway Resistance; Asthma; Bronchial Provocation Tests; Cross-Sectional Stu | 1986 |
Descriptive epidemiology of bronchial reactivity in an adult population: results from a community study.
Topics: Adult; Airway Resistance; Asthma; Bronchi; Bronchial Provocation Tests; Cross-Sectional Studies; Eng | 1987 |
Estimation and repeatability of the response to inhaled histamine in a community survey.
Topics: Adolescent; Adult; Airway Resistance; Asthma; Bronchi; Bronchial Provocation Tests; Cross-Sectional | 1987 |
Bronchial hyperresponsiveness in two populations of Australian schoolchildren. I. Relation to respiratory symptoms and diagnosed asthma.
Topics: Asthma; Australia; Bronchial Provocation Tests; Child; Cross-Sectional Studies; Female; Forced Expir | 1987 |
Prostaglandin D2 potentiates airway responsiveness to histamine and methacholine.
Topics: Adult; Airway Resistance; Asthma; Bradykinin; Bronchi; Bronchial Provocation Tests; Dose-Response Re | 1986 |
Epidemiological research in asthma: the need for a broad perspective.
Topics: Africa; Age Factors; Asia; Asthma; Cross-Sectional Studies; England; Epidemiologic Methods; Europe; | 1986 |
Comparison of drug responses in vivo and in vitro in airways of dogs with and without airway hyperresponsiveness.
Topics: Aerosols; Airway Resistance; Animals; Asthma; Bronchial Provocation Tests; Disease Models, Animal; D | 1986 |
Airway responses to methacholine and histamine in basenji greyhounds and other purebred dogs.
Topics: Aerosols; Airway Resistance; Animal Husbandry; Animals; Asthma; Bronchial Provocation Tests; Dogs; F | 1986 |
[Bronchial hyperreactivity. Methods of detection with pharmacologic substances].
Topics: Acetylcholine; Airway Obstruction; Asthma; Bronchial Provocation Tests; Carbachol; Histamine; Humans | 1986 |
Maximal airway narrowing in humans in vivo. Histamine compared with methacholine.
Topics: Adolescent; Adult; Asthma; Bronchi; Bronchial Provocation Tests; Diagnosis, Differential; Dose-Respo | 1986 |
[Bronchial hypersensitivity in infants with bronchial asthma].
Topics: Asthma; Bronchial Provocation Tests; Female; Histamine; Humans; Infant; Male; Pentetic Acid; Technet | 1986 |
Airway effects of purine nucleosides and nucleotides and release with bronchial provocation in asthma.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Asthma; Bronchi; Bronchial Provocation Te | 1986 |
Bradykinin-induced bronchoconstriction in humans. Mode of action.
Topics: Administration, Inhalation; Aged; Asthma; Bradykinin; Bronchi; Bronchial Provocation Tests; Capsaici | 1987 |
Bronchoprovocation test in the normal and in asthmatics.
Topics: Adult; Asthma; Bronchial Provocation Tests; Female; Histamine; Humans; Male; Methacholine Chloride; | 1986 |
Elevated bronchoalveolar lavage fluid histamine levels in allergic asthmatics are associated with methacholine bronchial hyperresponsiveness.
Topics: Adolescent; Adult; Asthma; Bronchial Provocation Tests; Forced Expiratory Volume; Histamine; Humans; | 1987 |
Airway responsiveness to histamine or methacholine: advances in measurement and interpretation.
Topics: Asthma; Bronchial Provocation Tests; Dose-Response Relationship, Drug; Histamine; Humans; Lung Disea | 1986 |
Acid anhydrides and asthma.
Topics: Anhydrides; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Haptens; Histamine; Humans; Hypers | 1987 |
[Sensitivity and specificity of the occlusion pressure method in measuring airway resistance compared to whole body plethysmography, studies within the scope of inhalative provocation tests].
Topics: Airway Resistance; Allergens; Asthma; Bronchial Provocation Tests; Child; Histamine; Humans; Plethys | 1987 |
[Nonspecific bronchial hyperreactivity in patients with hay fever and pollen-induced asthma].
Topics: Asthma; Bronchi; Bronchial Provocation Tests; Female; Histamine; Humans; Male; Pollen; Rhinitis, All | 1986 |
[Study of bronchial hyperreactivity in asthma by the curve response to eucapnia hyperventilation with cold and dry air].
Topics: Adolescent; Adult; Asthma; Bronchial Provocation Tests; Cold Temperature; Female; Forced Expiratory | 1986 |
Histamine as a modulator of airways hyperreactivity. Papers of a symposium of the Canadian Federation of Biological Societies. Guelph, Ontario, Canada, June 17, 1986.
Topics: Asthma; Histamine; Humans; Respiratory System | 1987 |
Recovery of FEV1 after histamine challenge in asthmatic children.
Topics: Adolescent; Asthma; Bronchial Provocation Tests; Child; Female; Forced Expiratory Volume; Histamine; | 1987 |
Unchanged bronchial reactivity after killed influenza virus vaccine in adult asthmatics.
Topics: Adult; Airway Resistance; Asthma; Bronchial Provocation Tests; Female; Histamine; Humans; Influenza | 1987 |
[Airway response in adult asthmatics].
Topics: Adolescent; Adult; Airway Obstruction; Asthma; Asthma, Exercise-Induced; Bronchial Provocation Tests | 1987 |
Effect of inhaled histamine on occlusion pressure and breathing pattern in asthmatic patients.
Topics: Administration, Inhalation; Adult; Asthma; Bronchial Provocation Tests; Female; Histamine; Humans; P | 1987 |
Airway responses in vitro following C5a des Arg-induced hyper-responsiveness in vivo in rabbits.
Topics: Airway Resistance; Animals; Asthma; Carbachol; Complement C5; Complement C5a, des-Arginine; Female; | 1987 |
Histamine challenge test in children using forced oscillation to measure total respiratory resistance.
Topics: Adolescent; Airway Resistance; Asthma; Bronchial Provocation Tests; Child; Female; Forced Expiratory | 1987 |
Changes in bronchial responsiveness to histamine at intervals after allergen challenge.
Topics: Adolescent; Adult; Asthma; Bronchi; Bronchial Provocation Tests; Female; Forced Expiratory Volume; H | 1987 |
[Bronchial reactivity. Method for nonspecific bronchial provocation].
Topics: Asthma; Bronchial Provocation Tests; Histamine; Humans; Occupational Diseases; Spirometry | 1986 |
[Reproducibility of the histamine and acetylcholine inhalation provocation test].
Topics: Acetylcholine; Adolescent; Adult; Asthma; Bronchial Provocation Tests; Female; Forced Expiratory Vol | 1987 |
Inspiratory impedance during histamine-induced bronchoconstriction in patients with bronchial asthma.
Topics: Adult; Airway Resistance; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Female; Fenoterol; H | 1987 |
[Histamine-dependent reactions in occupational allergic bronchial asthma of chemical etiology].
Topics: Air Pollutants, Occupational; Asthma; Formaldehyde; Histamine; Humans; Metallurgy; Metals; Occupatio | 1987 |
Direct evidence of a role for mast cells in the pathogenesis of antigen-induced bronchoconstriction.
Topics: Adult; Antigens; Asthma; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Histamine; Human | 1987 |
[Bronchial asthma and airway hypersensitivity--4) Relation between airway hypersensitivity and chemical mediators].
Topics: Asthma; Basophils; Histamine; Humans; Immunoglobulin E; Mast Cells; SRS-A | 1987 |
[Bronchial asthma and airway hypersensitivity--5) Test methods of airway hypersensitivity--reality and evaluation of bronchial provocation tests].
Topics: Acetylcholine; Asthma; Bronchial Provocation Tests; Evaluation Studies as Topic; Histamine; Humans; | 1987 |
Study of mediators of anaphylaxis in nasal wash fluids after aspirin and sodium metabisulfite nasal provocation in intolerant rhinitic patients.
Topics: Aspirin; Asthma; Drug Hypersensitivity; Histamine; Humans; Nasal Mucosa; Nasal Provocation Tests; Rh | 1987 |
Tachyphylaxis to inhaled histamine in asthmatic subjects.
Topics: Acetylcholine; Administration, Inhalation; Adolescent; Adult; Asthma; Bronchial Provocation Tests; F | 1987 |
Positive allergy prick tests associated with bronchial histamine responsiveness in an unselected population.
Topics: Adult; Asthma; Bronchi; Bronchial Diseases; Child; Female; Histamine; Humans; Immunoglobulin E; Male | 1986 |
[Bronchial provocation testing].
Topics: Acetylcholine; Asthma; Bronchial Provocation Tests; Histamine; Humans; Monitoring, Physiologic; Refe | 1986 |
Histamine challenge testing: comparison of three methods.
Topics: Adolescent; Adult; Aerosols; Asthma; Bronchial Provocation Tests; Forced Expiratory Volume; Histamin | 1986 |
Effect of an inhaled bronchodilator on histamine-induced cough in asthmatic subjects.
Topics: Adult; Aerosols; Asthma; Bronchial Provocation Tests; Cough; Female; Histamine; Humans; Isoprotereno | 1986 |
Discrimination between urticaria-prone and other allergic patients by intradermal skin testing with codeine.
Topics: Adult; Asthma; Codeine; Female; Histamine; Humans; Hypersensitivity; Male; Mast Cells; Middle Aged; | 1986 |
Comparison of cutaneous and bronchial reactivity to leukotriene D4 in humans.
Topics: Asthma; Bronchial Provocation Tests; Dermatitis, Atopic; Histamine; Humans; Male; Pulmonary Ventilat | 1986 |
Intracutaneous and skin prick testing with serotonin and histamine.
Topics: Adolescent; Adult; Asthma; Female; Histamine; Humans; Injections, Intradermal; Male; Middle Aged; Rh | 1986 |
[The effect of histamine and theophylline and the formation of E rosettes].
Topics: Asthma; Histamine; Humans; Melanoma; Rhinitis, Allergic, Seasonal; Rosette Formation; Theophylline | 1986 |
Effects of pulmonary inhalation of water and histamine aerosols on nasal airflow resistance in man.
Topics: Adolescent; Adult; Aerosols; Aged; Airway Resistance; Asthma; Bronchial Provocation Tests; Forced Ex | 1986 |
[A case of mite sensitive asthma without methacholine and histamine hyperresponsiveness].
Topics: Asthma; Bronchial Provocation Tests; Child; Histamine; Humans; Male; Methacholine Compounds; Mites | 1986 |
Pathophysiological condition of the nose of asthmatic children with subclinical nasal allergy.
Topics: Adolescent; Asthma; Basophils; Child; Child, Preschool; Eosinophils; Female; Histamine; Humans; Male | 1986 |
Mode of action of halothane on histamine-induced airway constriction in dogs with reactive airways.
Topics: Aerosols; Airway Resistance; Anesthesia, Inhalation; Animals; Asthma; Atropine; Bronchi; Dogs; Dose- | 1986 |
The effect of inhaled clonidine in patients with asthma.
Topics: Administration, Intranasal; Adolescent; Adult; Asthma; Clonidine; Eosinophils; Female; Forced Expira | 1986 |
Effect of whooping cough in infancy on subsequent lung function and bronchial reactivity.
Topics: Asthma; Bronchi; Bronchial Provocation Tests; Child; Female; Follow-Up Studies; Forced Expiratory Vo | 1986 |
[Reactivity of the smooth muscle of the respiratory tract in cats to histamine and acetylcholine administration in vitro after repeated administration of croton oil aerosol].
Topics: Acetylcholine; Aerosols; Animals; Asthma; Cats; Croton Oil; Female; Histamine; In Vitro Techniques; | 1986 |
Occupational asthma in sawmills of eastern Canada and United States.
Topics: Adult; Asthma; Bronchi; Canada; Forced Expiratory Volume; Histamine; Humans; Maximal Expiratory Flow | 1986 |
[Effect of ranitidine on the histamine-induced bronchial spasm in patients with bronchial asthma].
Topics: Adult; Asthma; Bronchi; Bronchial Provocation Tests; Bronchial Spasm; Female; Histamine; Humans; Mal | 1986 |
The relationship between acetylcholine- and histamine-induced constriction of large airways in normal subjects and subjects with asthma: a possible role for postreceptor mechanisms.
Topics: Acetylcholine; Asthma; Atropine; Bronchi; Dose-Response Relationship, Drug; Histamine; Humans; Recep | 1986 |
Effects of histamine and reproterol inhalation on mouth occlusion pressure in patients with bronchial asthma.
Topics: Adult; Asthma; Autonomic Nervous System; Bronchial Provocation Tests; Bronchodilator Agents; Drug Co | 1986 |
Exposure to a sensitizing occupational agent can cause a long-lasting increase in bronchial responsiveness to histamine in the absence of significant changes in airway caliber.
Topics: Airway Resistance; Asthma; Bronchi; Forced Expiratory Volume; Histamine; Humans; Male; Middle Aged; | 1986 |
Effect of sleep deprivation on overnight bronchoconstriction in nocturnal asthma.
Topics: Adult; Airway Resistance; Asthma; Circadian Rhythm; Electroencephalography; Female; Histamine; Human | 1986 |
Bronchial reactivity increases soon after the immediate response in dual-responding asthmatic subjects.
Topics: Adult; Airway Resistance; Allergens; Asthma; Bronchial Provocation Tests; Drug Interactions; Female; | 1987 |
A rapid challenge protocol for determination of non-specific bronchial responsiveness.
Topics: Adolescent; Adult; Aerosols; Asthma; Bronchial Provocation Tests; Bronchiectasis; Female; Histamine; | 1986 |
Prediction of airway responsiveness to allergen from skin sensitivity to allergen and airway responsiveness to histamine.
Topics: Allergens; Asthma; Bronchi; Bronchial Provocation Tests; Dose-Response Relationship, Immunologic; Hi | 1987 |
Prediction of airway responsiveness to allergen from skin sensitivity to allergen and airway responsiveness to histamine.
Topics: Allergens; Asthma; Bronchi; Bronchial Provocation Tests; Dose-Response Relationship, Immunologic; Hi | 1987 |
Prediction of airway responsiveness to allergen from skin sensitivity to allergen and airway responsiveness to histamine.
Topics: Allergens; Asthma; Bronchi; Bronchial Provocation Tests; Dose-Response Relationship, Immunologic; Hi | 1987 |
Prediction of airway responsiveness to allergen from skin sensitivity to allergen and airway responsiveness to histamine.
Topics: Allergens; Asthma; Bronchi; Bronchial Provocation Tests; Dose-Response Relationship, Immunologic; Hi | 1987 |
Prediction of airway responsiveness to allergen from skin sensitivity to allergen and airway responsiveness to histamine.
Topics: Allergens; Asthma; Bronchi; Bronchial Provocation Tests; Dose-Response Relationship, Immunologic; Hi | 1987 |
Prediction of airway responsiveness to allergen from skin sensitivity to allergen and airway responsiveness to histamine.
Topics: Allergens; Asthma; Bronchi; Bronchial Provocation Tests; Dose-Response Relationship, Immunologic; Hi | 1987 |
Prediction of airway responsiveness to allergen from skin sensitivity to allergen and airway responsiveness to histamine.
Topics: Allergens; Asthma; Bronchi; Bronchial Provocation Tests; Dose-Response Relationship, Immunologic; Hi | 1987 |
Prediction of airway responsiveness to allergen from skin sensitivity to allergen and airway responsiveness to histamine.
Topics: Allergens; Asthma; Bronchi; Bronchial Provocation Tests; Dose-Response Relationship, Immunologic; Hi | 1987 |
Prediction of airway responsiveness to allergen from skin sensitivity to allergen and airway responsiveness to histamine.
Topics: Allergens; Asthma; Bronchi; Bronchial Provocation Tests; Dose-Response Relationship, Immunologic; Hi | 1987 |
[Studies of the correlation between airway hyperreactivity and severity of disease in asthmatic children].
Topics: Acetylcholine; Adolescent; Asthma; Asthma, Exercise-Induced; Bronchial Provocation Tests; Child; Fem | 1986 |
Changes in flow-volume curve configuration with bronchoconstriction and bronchodilation.
Topics: Adult; Asthma; Bronchial Provocation Tests; Histamine; Humans; Isoproterenol; Lung; Peak Expiratory | 1986 |
[The nonadrenergic noncholinergic system in the regulation of bronchial tonus].
Topics: Adult; Asthma; Bronchi; Bronchial Spasm; Histamine; Humans; In Vitro Techniques; Male; Middle Aged; | 1986 |
[Evaluation of the bronchial provocation test with histamine in asthmatic children].
Topics: Adolescent; Asthma; Bronchial Provocation Tests; Bronchodilator Agents; Child; Forced Expiratory Vol | 1986 |
The temporal relationship between increases in airway responsiveness to histamine and late asthmatic responses induced by occupational agents.
Topics: Adolescent; Adult; Allergens; Asthma; Bronchial Provocation Tests; Female; Forced Expiratory Volume; | 1987 |
Relations between clinical signs and lung function in bronchial asthma: how is acute bronchial obstruction reflected in dyspnoea and wheezing?
Topics: Adult; Allergens; Asthma; Bronchial Provocation Tests; Dyspnea; Female; Histamine; Humans; Male; Res | 1986 |
Studies of sympatho-adrenal reactivity and adrenoceptor function in bronchial asthma.
Topics: Adrenal Glands; Asthma; Asthma, Exercise-Induced; Bronchial Provocation Tests; Bronchial Spasm; Epin | 1985 |
Histamine log(dose)-response curves in asthmatics. A comparison between the Wiesbadener Doppelinhalator and the De Vilbiss Model 645 nebulizer.
Topics: Adolescent; Adult; Aerosols; Asthma; Bronchial Provocation Tests; Dose-Response Relationship, Drug; | 1985 |
[Sites of airway contractions induced by inhalation of histamine, prostaglandin F2 alpha and leukotriene D4 in asthmatics--investigation by a cross-over method].
Topics: Adult; Asthma; Dinoprost; Female; Forced Expiratory Flow Rates; Histamine; Humans; Male; Maximal Exp | 1985 |
[Slow-reacting substance of anaphylaxis in sputa of asthmatics].
Topics: Adult; Asthma; Female; Histamine; Humans; Male; Middle Aged; Sputum; SRS-A | 1985 |
Quantitative aspects of the T cell proliferation response to antigen P1 from D. pteronyssinus: suppression by added histamine and limited effects of basophil depletion.
Topics: Allergens; Asthma; Basophils; Cell Division; Cells, Cultured; Dermatitis, Atopic; Histamine; Humans; | 1985 |
Advances in the use of inhalation provocation tests in clinical evaluation.
Topics: Airway Obstruction; Asthma; Bronchial Provocation Tests; Forced Expiratory Volume; Histamine; Humans | 1985 |
Mediators, airway responsiveness, and asthma.
Topics: Airway Resistance; Asthma; Bronchial Provocation Tests; Dinoprost; Histamine; Humans; Inflammation; | 1985 |
Increased responsiveness to methacholine and histamine after challenge with ultrasonically nebulised water in asthmatic subjects.
Topics: Adult; Airway Resistance; Asthma; Bronchi; Bronchial Provocation Tests; Female; Forced Expiratory Vo | 1985 |
Airway responsiveness to inhaled antigen, histamine, and methacholine in inbred, ragweed-sensitized dogs.
Topics: Animals; Asthma; Bronchial Provocation Tests; Disease Models, Animal; Dogs; Female; Histamine; Immun | 1985 |
Upper airway response during bronchoprovocation and asthma attack.
Topics: Adult; Aged; Airway Resistance; Asthma; Bronchial Provocation Tests; Dose-Response Relationship, Dru | 1985 |
Histamine-induced asthma in children: effects on the ventilation-perfusion relationship.
Topics: Adolescent; Albuterol; Arteries; Asthma; Bronchial Provocation Tests; Carbon Dioxide; Cardiac Output | 1985 |
Actions of disodium cromoglycate (DSCG) on human skin responses to histamine, codeine and Paf-acether.
Topics: Adult; Asthma; Codeine; Cromolyn Sodium; Histamine; Humans; Mast Cells; Platelet Activating Factor; | 1985 |
Bronchial challenge with room temperature isocapnic hyperventilation. A comparison with histamine challenge.
Topics: Adolescent; Adult; Asthma; Bronchial Provocation Tests; Carbon Dioxide; Child; Dyspnea; Female; Forc | 1985 |
Mediators and asthma.
Topics: Adenosine; Asthma; Bradykinin; Bronchial Spasm; Chemotactic Factors; Chemotaxis, Leukocyte; Histamin | 1985 |
Increased bronchial responsiveness to exercise and histamine after allergen challenge in children with asthma.
Topics: Adolescent; Allergens; Asthma; Asthma, Exercise-Induced; Bronchi; Child; Forced Expiratory Volume; H | 1986 |
Effect of atropine on the hyperresponsiveness of ragweed-sensitized canine tracheal smooth muscle.
Topics: Animals; Asthma; Atropine; Bronchial Spasm; Disease Models, Animal; Dogs; Dose-Response Relationship | 1986 |
The immediate asthmatic response to allergen challenge.
Topics: Adolescent; Adult; Asthma; Body Temperature; Bronchi; Bronchial Provocation Tests; Histamine; Humans | 1986 |
Variability of airway responsiveness to histamine aerosol in normal subjects. Role of deposition.
Topics: Adult; Aerosols; Aged; Asthma; Bronchi; Dose-Response Relationship, Drug; Female; Histamine; Humans; | 1985 |
Passive cigarette smoking and patients with asthma.
Topics: Adult; Asthma; Bronchi; Female; Histamine; Humans; Lung Volume Measurements; Male; Tobacco Smoke Pol | 1985 |
Increased bronchial responsiveness caused by ingestion of ice.
Topics: Adolescent; Adult; Asthma; Bronchial Provocation Tests; Child; Female; Histamine; Humans; Ice; India | 1985 |
The effect of aspirin during aspirin "desensitisation" on compound 48/80 and histamine-induced skin responses in aspirin-sensitive asthmatics.
Topics: Adult; Aspirin; Asthma; Desensitization, Immunologic; Drug Hypersensitivity; Female; Histamine; Huma | 1985 |
Damage of the airway epithelium and bronchial reactivity in patients with asthma.
Topics: Adolescent; Adult; Asthma; Bronchi; Bronchial Provocation Tests; Epithelium; Female; Forced Expirato | 1985 |
Increases in airway reactivity to histamine and inflammatory cells in bronchoalveolar lavage after the late asthmatic response in an animal model.
Topics: Animals; Asthma; Bronchi; Bronchial Provocation Tests; Histamine; Pneumonia; Pulmonary Alveoli; Rabb | 1985 |
[Comparison of airway responsiveness to inhaled histamine with three methods in patients with bronchial asthma and chronic pulmonary emphysema].
Topics: Airway Resistance; Asthma; Bronchial Provocation Tests; Histamine; Humans; Pulmonary Emphysema | 1985 |
Histamine in late asthmatic reactions following house-dust mite inhalation.
Topics: Adolescent; Adult; Aged; Asthma; Bronchial Provocation Tests; Dust; Female; Histamine; Humans; Male; | 1985 |
Prevalence and nature of bronchial hyperresponsiveness in subjects with chronic obstructive pulmonary disease.
Topics: Adult; Aged; Asthma; Bronchi; Bronchial Provocation Tests; Female; Histamine; Humans; Lung Diseases, | 1985 |
Ventilation-perfusion relationships in symptomatic asthma. Response to oxygen and clemastine.
Topics: Adult; Asthma; Clemastine; Female; Histamine; Humans; Hypoxia; Male; Middle Aged; Oxygen Inhalation | 1985 |
Association between rise in antibodies and increase in airway sensitivity after intramuscular injection of killed influenza virus in asthmatic patients.
Topics: Adolescent; Adult; Antibodies, Viral; Asthma; Bronchial Provocation Tests; Female; Hemagglutinins, V | 1985 |
Occupational asthma due to formaldehyde.
Topics: Adult; Asthma; Bronchial Provocation Tests; Female; Formaldehyde; Histamine; Humans; Male; Middle Ag | 1985 |
How many spirograms for a histamine challenge?
Topics: Adult; Asthma; Bronchial Provocation Tests; Bronchospirometry; Dose-Response Relationship, Drug; For | 1985 |
[Comparison of the loading test and the histamine test in patients with bronchial asthma].
Topics: Adolescent; Adult; Asthma; Bronchial Provocation Tests; Exercise Test; Female; Histamine; Humans; Ma | 1985 |
[Formes frustes of bronchial asthma].
Topics: Adolescent; Adult; Aged; Asthma; Diagnosis, Differential; Eosinophils; Female; Histamine; Humans; Le | 1985 |
The predictive value of bronchial histamine challenge in the diagnosis of bronchial asthma.
Topics: Adolescent; Adult; Aged; Asthma; Female; Forced Expiratory Volume; Histamine; Humans; Male; Middle A | 1985 |
Bronchial hyperreactivity to histamine in aspirin sensitive asthmatics: relationship to aspirin threshold and effect of aspirin desensitisation.
Topics: Adult; Aspirin; Asthma; Bronchi; Bronchial Provocation Tests; Desensitization, Immunologic; Dose-Res | 1985 |
Effects of histamine on lung permeability in normal and asthmatic subjects.
Topics: Adult; Albuterol; Asthma; Histamine; Humans; Lung; Middle Aged; Mucous Membrane; Peak Expiratory Flo | 1985 |
Nasal challenge with serotonin and histamine in normal persons.
Topics: Adolescent; Adult; Asthma; Female; Histamine; Humans; Male; Middle Aged; Nasal Mucosa; Rhinitis; Ser | 1985 |
Diagnosis and immunotherapy of mould allergy. II. Reproducibility and relationship between skin sensitivity estimated by end-point titration and histamine equivalent reaction using skin prick test and intradermal test.
Topics: Adolescent; Adult; Allergens; Alternaria; Asthma; Cladosporium; Dose-Response Relationship, Immunolo | 1985 |
Reproducibility of skin sensitivity using a quantitative skin prick test.
Topics: Adult; Asthma; Dose-Response Relationship, Immunologic; Female; Histamine; Humans; Male; Skin Tests; | 1985 |
Kinetics of the recovery of airway response caused by inhaled histamine.
Topics: Adult; Aerosols; Airway Resistance; Asthma; Female; Forced Expiratory Volume; Gases; Histamine; Huma | 1985 |
Mast cell and histamine content of human bronchoalveolar lavage fluid.
Topics: Adult; Aged; Asthma; Bronchi; Carcinoma, Bronchogenic; Cell Count; Female; Histamine; Humans; Lung D | 1985 |
[Bronchial provocation with histamine in various respiratory diseases].
Topics: Adolescent; Adult; Aged; Asthma; Bronchial Provocation Tests; Bronchitis; Female; Histamine; Humans; | 1985 |
The effect of dipyridamole on histamine- and adenosine-induced bronchoconstriction in normal and asthmatic subjects.
Topics: Adenosine; Administration, Intranasal; Adult; Asthma; Bronchi; Dipyridamole; Female; Histamine; Huma | 1985 |
Circadian variation in airway function.
Topics: Acetylcholine; Asthma; Bronchi; Circadian Rhythm; Epinephrine; Forced Expiratory Volume; Histamine; | 1985 |
[Airway hyperresponsiveness caused by infection and inflammation].
Topics: Adult; Animals; Asthma; Bronchi; Dogs; Female; Histamine; Humans; Male; Respiratory Tract Infections | 1985 |
Bronchial histamine challenge. A combined interrupter-dosimeter method compared with a standard method.
Topics: Adolescent; Adult; Aged; Asthma; Bronchial Provocation Tests; Female; Forced Expiratory Volume; Hist | 1985 |
[Studies on exercise-induced asthma in adult asthmatic patients--relationship between the site of airway obstruction and changes in plasma histamine level].
Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Exercise Test; Female; Histamine; Humans; Male; | 1985 |
[Bronchial reactivity to inhaled histamine in asthma].
Topics: Adolescent; Adult; Aerosols; Asthma; Bronchial Provocation Tests; Female; Histamine; Humans; Male | 1985 |
Plasma histamine concentration during propranolol induced bronchoconstriction.
Topics: Adult; Airway Resistance; Asthma; Female; Histamine; Humans; Male; Peak Expiratory Flow Rate; Propra | 1985 |
[Bronchial hypersensitivity in preschool children with bronchial asthma measured by a new method].
Topics: Aerosols; Asthma; Bronchi; Bronchial Provocation Tests; Child; Child, Preschool; Female; Histamine; | 1985 |
[Leukocyte sensitivity in bronchial asthma in children. 1. Histamine liberation of leukocytes in bronchial asthma in children].
Topics: Allergens; Asthma; Child; Child, Preschool; Histamine; Histamine Release; Humans; Leukocytes | 1970 |
Analysis of sputum for presence of pharmacologically active substances in cases of bronchial asthma and other respiratory diseases.
Topics: Asthma; Chromatography; Histamine; Histamine Release; Humans; Respiratory Tract Diseases; Serotonin; | 1970 |
Direct recovery of histamine from cutaneous anaphylaxis in man.
Topics: Anaphylaxis; Animals; Antigens; Asthma; Guinea Pigs; Histamine; Histamine H1 Antagonists; Histamine | 1971 |
Use of practolol in asthmatics: a plea for caution.
Topics: Acetanilides; Acetylcholine; Amino Alcohols; Animals; Antigen-Antibody Reactions; Asthma; Bradykinin | 1971 |
Studies of histamine, serotonin and these pexic actions in asthmatic children.
Topics: Animals; Asthma; Child; Chromones; Cromolyn Sodium; gamma-Globulins; Guinea Pigs; Histamine; Humans; | 1970 |
[Allergic reactions and endocrine regulation].
Topics: Adrenal Cortex Hormones; Asthma; Endocrine System Diseases; Estrogens; Female; Histamine; Histamine | 1970 |
[Significance of mediator agents in asthma in animal experiments and clinical practice].
Topics: Animals; Antigen-Antibody Reactions; Asthma; Autacoids; Bradykinin; Bronchi; Cromolyn Sodium; Epinep | 1972 |
Cortisone withdrawal rebound phenomena and histamine.
Topics: Asthma; Histamine; Histamine Release; Humans; Ileum; Muscle Contraction; Prednisone; Substance Withd | 1971 |
[Changes in serum activity of trypsin in patients with bronchial asthma between attacks and during experimental anaphylactic shock].
Topics: Anaphylaxis; Animals; Aprotinin; Asthma; Guinea Pigs; Histamine; Histamine Release; Humans; Trypsin | 1971 |
Treatment of status asthmaticus.
Topics: Animals; Asthma; Dogs; Histamine; Histamine Release; Humans; Meperidine; Morphine | 1973 |
Exercise-induced bronchoconstriction and histamine release.
Topics: Adult; Airway Resistance; Antigen-Antibody Reactions; Asthma; Atropine; Bronchi; Constriction; Cromo | 1971 |
[Use of histaglobin in the treatment of bronchial asthma].
Topics: Adolescent; Asthma; Child; Drug Combinations; Female; gamma-Globulins; Histamine; Humans; Male | 1973 |
Further studies of concordant fluctuation in sensitivity of peripheral leucocytes to unrelated allergens and the meaning of nonspecific 'densensitization'.
Topics: Adolescent; Allergens; Antigen-Antibody Reactions; Asthma; Basophils; Child; Desensitization, Immuno | 1973 |
[The criterion of the histamino-agglutinating factor and etiological classification of asthma patients].
Topics: Agglutination Tests; Allergens; Asthma; Bronchial Spasm; Bronchitis; Diagnosis, Differential; Histam | 1973 |
Relationship between antigen induced histamine release and cyclic AMP level in human leukocytes.
Topics: Allergens; Animals; Antibodies, Anti-Idiotypic; Antigen-Antibody Reactions; Antigens; Asthma; Cells, | 1974 |
[Serotonin level in patients with bronchial asthma in connection with treatment by histaglobulin and corticosteroids].
Topics: Adolescent; Adult; Aged; Asthma; Female; gamma-Globulins; Glucocorticoids; Histamine; Humans; Male; | 1974 |
[Studies on the antiallergic and corticosecretory effects of 8-phenethyl-1-oxa-3,8-diaza-spiro(4,5)decan-2-one (fenspiride, JP 428)].
Topics: Anaphylaxis; Animals; Asthma; Dose-Response Relationship, Drug; Glucocorticoids; Guinea Pigs; Histam | 1972 |
Effect of chloroquine on histamine-induced bronchial asthma in the guinea-pig.
Topics: Animals; Asthma; Chloroquine; Female; Guinea Pigs; Histamine; Histamine H1 Antagonists; Lung; Male | 1974 |
Antihistaminic action of nicotinamide.
Topics: Aerosols; Anaphylaxis; Animals; Asthma; Bronchi; Guinea Pigs; Histamine; Histamine H1 Antagonists; I | 1974 |
Bronchoconstriction tests in epidemiology. Discussion.
Topics: Acetylcholine; Air Pollution; Animals; Asthma; Congresses as Topic; Dogs; Epidemiologic Methods; His | 1973 |
[Our experiences in the treatment of patients with pulmonary tuberculosis and asthma with Histaglobine].
Topics: Asthma; gamma-Globulins; Histamine; Humans; Tuberculosis, Pulmonary | 1966 |
[Histaglobin in the treatment of eczema and neurodermatitis in children].
Topics: Asthma; Child; Eczema; gamma-Globulins; Histamine; Humans; Neurodermatitis | 1966 |
[Bronchodilator effects of CO2 during an asthma attack accompanying respiratory alkalosis and disturbances in the distribution of respiratory irrigation].
Topics: Alkalosis; Asthma; Bronchi; Bronchodilator Agents; Carbon Dioxide; Histamine; Humans; Hyperventilati | 1967 |
[Studies of allergic reaction of the respiratory tract in animal experiments].
Topics: Allergens; Animals; Asthma; Guinea Pigs; Histamine; Histamine Release; Ovalbumin; Perfusion; Respira | 1966 |
[Experiences in the use of histaglobin in young children, suffering from bronchial asthma and asthmatic bronchitis].
Topics: Asthma; Bronchitis; Child; Child, Preschool; Female; gamma-Globulins; Histamine; Histamine H1 Antago | 1966 |
Asthmatic breathing in mice.
Topics: Animals; Asthma; Bradykinin; Histamine; Mice; Serotonin; Sympatholytics | 1968 |
Bronchial sensitivity to allergen with and without previous heparin administration.
Topics: Allergens; Amine Oxidase (Copper-Containing); Asthma; Blood Platelets; Complement Inactivator Protei | 1968 |
[Treatment of bronchial asthma in children with histaglobin and its effect on several aspects of histamine metabolism].
Topics: Asthma; Child, Preschool; gamma-Globulins; Histamine; Humans; Infant | 1968 |
[Clinical study on asthma in children].
Topics: Asthma; Blood Gas Analysis; Child; Child, Preschool; Eosinophils; Female; gamma-Globulins; Histamine | 1969 |
Studies on bronchial asthma, concerning histamine release reaction.
Topics: Asthma; Basophils; Dust; Eosinophils; Histamine; Histamine Release; Humans; Skin Tests | 1969 |
[Preliminary note on the clinical trial of a combination of histamine, human gamma globulin and serotonin for the radical desensitizing therapy of allergic diseases, with special reference to bronchial asthma, headaches and allergic dermatoses. I].
Topics: Adolescent; Adult; Aged; Asthma; Child; Dermatitis, Contact; Desensitization, Immunologic; Female; g | 1969 |
[Our experience in the treatment of asthmatic syndromes in children with intradermal histaglobin and gamma globulin].
Topics: Asthma; Bronchitis; Child; Child, Preschool; Female; gamma-Globulins; Histamine; Humans; Infant; Inj | 1970 |
[Effect of injections of histaglobin on serum antigammaglobulin levels in children with allergic diseases].
Topics: Asthma; Child; Child, Preschool; gamma-Globulins; Histamine; Humans; Infant | 1970 |
[Possibilities of a causative therapy of asthma in the child].
Topics: Adolescent; Asthma; Child; Child, Preschool; Drug Synergism; gamma-Globulins; Histamine; Humans | 1969 |
[Effect of glucocorticoid therapy on the indicators of biologically active substances in the blood of children with bronchial asthma].
Topics: Acetylcholine; Amine Oxidase (Copper-Containing); Asthma; Child; Cholinesterases; Heparin; Histamine | 1974 |
Bronchial reactivity to inhaled histamine in asthmatic patients, before and after administration of atropine, phentolamine or disodium cromoglycate.
Topics: Adult; Aerosols; Airway Obstruction; Airway Resistance; Asthma; Atropine; Bronchi; Cromolyn Sodium; | 1974 |
[Intal in the treatment of atopic extrinsic bronchial asthma. II. Effect of intal on histamine concentration and blastic index in peripheral blood].
Topics: Asthma; Cromolyn Sodium; Histamine; Humans; Hypersensitivity, Immediate; Lymphocyte Activation | 1974 |
[Mucopolysaccharides of lung tissue in experimental allergic conditions. 3. Isolation of acid mucopolysaccharides from papain digested lung tissue of guinea pigs].
Topics: Anaphylaxis; Animals; Asthma; Glycosaminoglycans; Guinea Pigs; Histamine; Lung; Papain | 1967 |
[Mucopolysaccharides of lung tissue in experimental allergic conditions. II. Chromatography on ecteol cellulose of glucosaminoglucanes from papain digested lung tissue of guinea pigs].
Topics: Anaphylaxis; Animals; Asthma; Chromatography; Glycoproteins; Glycosaminoglycans; Guinea Pigs; Hexosa | 1967 |
The antihistaminic effect of human eosinophils.
Topics: Anaphylaxis; Asthma; Dermatitis, Atopic; Dermatitis, Exfoliative; Eczema; Eosinophils; Exanthema; Fe | 1970 |
Histochemical evidence for a functional duality of mast cells in human lymph nods.
Topics: Arthritis, Rheumatoid; Asthma; Glycosaminoglycans; Histamine; Histocytochemistry; Humans; Lung Neopl | 1972 |
The role of the autonomic nervous system in the pathogenesis of allergy, with special reference of organ vagotonia.
Topics: Acetylcholine; Antibody Formation; Asthma; Bradykinin; Bronchi; Carotid Sinus; Histamine; Hypersensi | 1973 |
[Evidence of hypersensitivity of the bronchial muscaluture of asthmatics].
Topics: Asthma; Bronchi; Dust; Histamine; Humans; Hypersensitivity; Manometry; Methods; Respiratory Function | 1968 |
[Several indices of the state of neurohumoral regulation in bronchial asthma in children of preschool and early school age].
Topics: Acetylcholine; Amine Oxidase (Copper-Containing); Asthma; Child; Child, Preschool; Epinephrine; Hist | 1968 |
[On pathogenesis and treatment of allergic respiratory diseases in young children].
Topics: Acetylcholine; Adrenal Glands; Adrenocorticotropic Hormone; Allergens; Asthma; Blood Platelets; Bron | 1968 |
Intermittent corticotrophin treatment: ventilatory tests in asthmatic subjects.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aged; Asthma; Female; Histamine; Humans; Hydroco | 1969 |
[Experimental asthma in guinea pigs and autonomic mediators].
Topics: Animals; Asthma; Atropine; Autonomic Agents; Cyclic AMP; Disease Models, Animal; Guinea Pigs; Hexame | 1972 |
Cyclic AMP metabolism in asthma: studies with leukocytes and lymphocytes.
Topics: Asthma; Bicarbonates; Cell Separation; Culture Media; Cyclic AMP; Dose-Response Relationship, Drug; | 1974 |
Changes in total histamine content of white blood cells (WBC) in allergy patients.
Topics: Adrenocorticotropic Hormone; Adult; Asthma; Diet Therapy; Eosinophils; Female; Histamine; Humans; Le | 1973 |
Effects of glucocorticosteroids on the urinary excretion of cyclic AMP and electrolytes by asthmatic children.
Topics: 17-Hydroxycorticosteroids; Adolescent; Asthma; Child; Chlorides; Circadian Rhythm; Creatinine; Cycli | 1974 |
Pharmacological mediators in asthma.
Topics: Allergens; Animals; Antigen-Antibody Reactions; Asthma; Basophils; Bronchi; Cyclic AMP; Depression, | 1974 |
[Studies with experimental bronchospasm (histamine provocation test) for determination of the efficacy of an antihistaminic].
Topics: Adolescent; Adult; Asthma; Bronchial Spasm; Histamine; Histamine H1 Antagonists; Humans; Respiratory | 1966 |
[Studies on tetrahydroisoquinoline compounds. (3). Pharmacodynamics of 1-(3,4,5-trimethoxybenzyl)-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline HC1 (AQ-110)].
Topics: Animals; Asthma; Bronchi; Bronchodilator Agents; Ethanolamines; Gastrointestinal Motility; Guinea Pi | 1967 |
Coincident basophilic chronic myelogenous leukemia and pulmonary tuberculosis associated with extreme elevations of blood histamine levels and maturity onset asthma.
Topics: Aging; Alkaline Phosphatase; Asthma; Chromosome Aberrations; Chromosome Disorders; Histamine; Histam | 1968 |
Cardiopulmonary effects of antimalarial drugs. 1. 4-Aminoquinolines: chloroquine quinetholate.
Topics: Anaphylaxis; Animals; Arrhythmias, Cardiac; Asthma; Blood Pressure; Chloroform; Chloroquine; Dopamin | 1970 |
Autacoids in sputum in cases of bronchial asthma and other respiratory diseases.
Topics: Acetylcholine; Asthma; Bradykinin; Bronchitis; Eosinophilia; Histamine; Humans; Lung Abscess; Seroto | 1970 |
Release of kinins from site of wheal-and-flare allergic skin reactions.
Topics: Adult; Allergens; Angioedema; Antigen-Antibody Reactions; Asthma; Autacoids; Chromatography, Gel; Ch | 1970 |
Resistance to beta-adrenoceptor stimulants and death from bronchial asthma.
Topics: Adrenergic beta-Agonists; Aerosols; Animals; Asthma; Blood Pressure; Bronchodilator Agents; Dogs; Dr | 1971 |
[Influence of atropine and antihistaminics on the bronchial response to aerosols of pneumallergens in asthma].
Topics: Acetylcholine; Adult; Aerosols; Allergens; Asthma; Atropine; Bronchi; Bronchial Spasm; Histamine; Hi | 1970 |
[Mediator substances and their effect on the lung and respiration in lung diseases].
Topics: Acetylcholine; Anaphylaxis; Asthma; Autacoids; Bradykinin; Histamine; Humans; Lung Diseases; Muscle, | 1970 |
Resistance to -adrenoceptor stimulants (a possible explanation for the rise in ashtma deaths).
Topics: Adrenergic beta-Agonists; Amino Alcohols; Animals; Arteries; Asthma; Bronchial Spasm; Bronchodilator | 1971 |
Late asthmatic responses induced by ragweed pollen allergen.
Topics: Adolescent; Adult; Allergens; Asthma; Circadian Rhythm; Eosinophils; Histamine; Humans; Hypersensiti | 1974 |
[Pharmacodynamic signs of consolidated airway obstruction].
Topics: Acetylcholine; Aerosols; Airway Obstruction; Airway Resistance; Asthma; Bronchial Spasm; Bronchodila | 1974 |
Histamine and metacholine challenge in the testing of bronchial reactivity.
Topics: Adolescent; Adult; Aged; Asthma; Bronchi; Bronchitis; Female; Histamine; Humans; Hypersensitivity; M | 1974 |
Estimation of histamine threshold by means of measurement of the work of breathing.
Topics: Adolescent; Adult; Aerosols; Age Factors; Aged; Asthma; Bronchi; Bronchial Spasm; Bronchitis; Coca; | 1972 |
Blood histamine in pulmonary diseases.
Topics: Adult; Asthma; Byssinosis; Eosinophilia; Eosinophils; Female; Histamine; Humans; Leukocyte Count; Lu | 1972 |
[Characteristics of histamine metabolism in silicosis].
Topics: Animals; Asthma; Berylliosis; Bronchitis; Chronic Disease; Histamine; Humans; Male; Pneumoconiosis; | 1972 |
[Asthma sputum as a clinical-therapeutic, patho-physiological and immunological problem].
Topics: Airway Obstruction; Animals; Antigen-Antibody Complex; Asthma; Bacteria; Bradykinin; Expectorants; G | 1972 |
Provocation of bronchial obstruction in bronchial asthma by dilute histamine aerosols.
Topics: Aerosols; Asthma; Bronchi; Histamine; Humans; Lung; Methods; Respiration; Spirometry; Time Factors; | 1972 |
Cross tolerance to histamine by the chronic administration of histamine analogues.
Topics: Aerosols; Animals; Asthma; Blood Pressure; Body Weight; Cats; Desensitization, Immunologic; Dogs; Dr | 1972 |
[Histamine changes in asthmatic conditions].
Topics: Adult; Aged; Asthma; Bronchial Spasm; Female; Histamine; Humans; Male; Middle Aged | 1973 |
Discharge patterns of the lung stretch receptors and activation of deflation fibres in anaphylactic bronchial asthma.
Topics: Animals; Asthma; Electrophysiology; Guinea Pigs; Histamine; Mechanoreceptors; Respiration; Respirato | 1973 |
A prospective study on chronic respiratory disease in children. I. Aim and methods, results of the first year.
Topics: Age Factors; Air Pollution; Asthma; Bronchitis; Child; Cough; Dyspnea; Female; Histamine; Humans; Lu | 1973 |
[Changes in the elimination of histamine, noradrenaline, adrenaline and vanilmandelic acid during high-mountain climatic therapy at Strbske Pleso].
Topics: Altitude; Amines; Asthma; Balneology; Climate; Czechoslovakia; Epinephrine; Female; Health Resorts; | 1973 |
Spectrum of asthma in children. II. Allergic components.
Topics: Adolescent; Albumins; Asthma; Child; Dust; Eczema; Eosinophils; Female; Histamine; Humans; Immunoglo | 1973 |
[Lymphocyte transformation test and blood histamine level in bronchial asthma in exacerbations and remissions].
Topics: Adult; Asthma; Female; Histamine; Humans; Lymphocyte Activation; Male; Middle Aged; Remission, Spont | 1973 |
[Relationship between hemocoagulation and histamine metabolism in patients with bronchial asthma].
Topics: Asthma; Blood Coagulation; Heparin; Histamine; Humans | 1973 |
Maximal expiratory flow rates and airway resistance following histamine aerosols in asthmatics.
Topics: Adult; Aerosols; Airway Resistance; Asthma; Bronchi; Constriction; Female; Histamine; Humans; Male; | 1973 |
[Effects of histamine aerosols in asthmatic patients. Changes in maximum expiratory flow and airway resistance].
Topics: Aerosols; Airway Resistance; Asthma; Bronchial Spasm; Histamine; Humans; Plethysmography; Pulmonary | 1973 |
[Histamine reactivity of the bronchial tree in the normal child. Preliminary results].
Topics: Adolescent; Aerosols; Airway Resistance; Asthma; Child; Dose-Response Relationship, Drug; Drug Hyper | 1973 |
[Studies on the histamine levels in the blood and sputum of children in bronchial asthma (author's transl)].
Topics: Adolescent; Age Factors; Asthma; Child; Histamine; Humans; Sputum; Time Factors | 1973 |
[Change in the blood content of certain biologically active substances in specific hyposensitization of children with bronchial asthma].
Topics: Adolescent; Asthma; Child; Child, Preschool; Chronic Disease; Desensitization, Immunologic; Dust; He | 1973 |
Bronchial inhalation procedures in asthmatics.
Topics: Adolescent; Adult; Aged; Antigens; Asthma; Bronchi; Buffers; Chronic Disease; Dust; Histamine; Human | 1974 |
Acute airway obstruction in rhesus monkeys induced by pharmacologic and immunologic stimuli.
Topics: Aerosols; Airway Obstruction; Animals; Antigens; Ascaris; Asthma; Disease Models, Animal; Histamine; | 1974 |
Histamine metabolism in asthma.
Topics: Acetates; Asthma; Child; Child, Preschool; Chromatography, Gas; Diet Therapy; Fluorometry; Histamine | 1974 |
Diagnosis of multiple inhalant allergies in children by radioimmunoassay.
Topics: Adolescent; Adult; Allergens; Angioedema; Antibody Formation; Asthma; Child; Child, Preschool; Derma | 1974 |
[The histamine induced eosinophilotatic activity in patients with allergic bronchial asthma. In vivo studies in man with Rebuck's skin window technic].
Topics: Asthma; Eosinophils; Histamine; Humans; Hypersensitivity; Skin Window Technique | 1967 |
Occupational asthma following inhalation of moth particles.
Topics: Adult; Allergens; Asthma; Desensitization, Immunologic; Histamine; Humans; Immunodiffusion; Immunoel | 1967 |
[The histamine-diaminoxidase system in healthy children and in patients with bronchial asthma during the interparoxysmal period].
Topics: Amine Oxidase (Copper-Containing); Asthma; Child; Child, Preschool; Eosinophilia; Female; Growth; Hi | 1967 |
[Provocative tests in patients with asthma].
Topics: Acetylcholine; Allergens; Asthma; Histamine; Humans; Respiratory Hypersensitivity | 1972 |
[Clinical serology and immunology of respiratory hypersensitivity].
Topics: Antigen-Antibody Reactions; Asthma; Desensitization, Immunologic; Histamine; Humans; Hypersensitivit | 1972 |
[Pathophysiology of bronchial asthma].
Topics: Asthma; Bradykinin; Bronchi; Histamine; Humans; Hydrogen-Ion Concentration; Lung; Muscle, Smooth; Ra | 1972 |
Aerosols and aerosol propellants in asthma.
Topics: Aerosols; Animals; Asthma; Bradycardia; Bronchial Spasm; Cats; Dogs; Electrocardiography; Histamine; | 1971 |
Muramidase activity in blood serum of patients with allergic bronchial asthma.
Topics: Acetylcholine; Adult; Asthma; Epinephrine; Heparin; Histamine; Humans; Micrococcus; Middle Aged; Mur | 1971 |
Significance of histaminopexy in pulmonary tuberculosis.
Topics: Adolescent; Adult; Aged; Asthma; Blood Proteins; Female; Follow-Up Studies; Histamine; Humans; Male; | 1968 |
[Use of pharmacodynamic aerosols in industrial medicine diagnostics].
Topics: Acetylcholine; Aerosols; Airway Resistance; Allergens; Asthma; Bronchi; Bronchitis; Environmental Ex | 1971 |
A clinical study of an unusual case of asthma associated with urticaria pigmentosa.
Topics: Asthma; Blister; Child, Preschool; Chlorpheniramine; Codeine; Histamine; Humans; Male; Methysergide; | 1966 |
Nonspecificity of the bronchoconstricting effect of histamine and acetyl-beta-methylcholine in patients with obstructive airway disease.
Topics: Adolescent; Adult; Aged; Asthma; Bronchi; Bronchitis; Female; Histamine; Humans; Male; Methacholine | 1966 |
Clinical significance of bronchial sensitivity to acetylcholine and histamine in bronchial asthma.
Topics: Acetylcholine; Adolescent; Adult; Asthma; Female; Histamine; Humans; Hypersensitivity, Immediate; Ma | 1966 |
The metabolism of C14 in histamine in subjects with bronchial asthma.
Topics: Asthma; Carbon Isotopes; Chromatography, Paper; Histamine; Humans; Lung | 1966 |
New Orleans asthma. I. Characterization of individuals involved in epidemics.
Topics: Adolescent; Adult; Aged; Allergens; Asthma; Bronchi; Child; Disease Outbreaks; Female; Histamine; Hu | 1967 |
Bronchial hypersensitivity to mecholyl and histamine in asthma subjects.
Topics: Adolescent; Adult; Aged; Asthma; Bronchi; Drug Hypersensitivity; Female; Histamine; Humans; Male; Me | 1967 |
Concerning the nature of intolerance to aspirin.
Topics: Aminopyrine; Antipyrine; Aspirin; Asthma; Chemoreceptor Cells; Drug Hypersensitivity; Edema; Histami | 1967 |
Efficacy of a new bronchodilator, soterenol, on experimental locked-lung syndrome in dogs.
Topics: Anilides; Animals; Asthma; Bronchodilator Agents; Dogs; Female; Histamine; Hypercapnia; Isoprotereno | 1968 |
The binding of histamine by normal and allergic human serum.
Topics: Asthma; Carbon Isotopes; Chromatography; Drug Hypersensitivity; Electrophoresis; Histamine; Histamin | 1969 |
Circadian reactivity rhythm of human skin to house dust, penicillin, and histamine.
Topics: 17-Hydroxycorticosteroids; Adolescent; Adult; Allergens; Animals; Asthma; Circadian Rhythm; Computer | 1969 |
Histamine release from leukocytes with antigen E and whole ragweed extract.
Topics: Antigens; Asthma; Histamine; Humans; Leukocytes; Plant Extracts; Pollen; Rhinitis, Allergic, Seasona | 1970 |
The effect of agents used in the treatment of bronchial asthma on carbohydrate metabolism and histamine sensitivity after beta-adrenergic blockade.
Topics: Adenine Nucleotides; Adrenal Cortex Hormones; Adrenalectomy; Alloxan; Aminophylline; Animals; Antige | 1970 |
The role of atropine as a mediator blocker of induced bronchial obstruction.
Topics: Adolescent; Adult; Airway Resistance; Antigen-Antibody Reactions; Asthma; Atropine; Diphenhydramine; | 1970 |
Where is the allergic reaction in ragweed asthma?
Topics: Adult; Asthma; Histamine; Humans; Phytotherapy; Pollen; Spirometry | 1971 |
[Experimental study on the ciliary movement of the respiratory epithelium in bronchial asthma. I].
Topics: Acetylcholine; Allergens; Animals; Asthma; Bronchi; Cilia; Guinea Pigs; Histamine; In Vitro Techniqu | 1966 |
[Dynamics of various neuro-humoral indices in bronchial asthma in children].
Topics: Adolescent; Asthma; Child; Child, Preschool; Female; Heparin; Histamine; Humans; Male; Serotonin | 1969 |
IgE concentrations in children with atopic diseases. A clinical study.
Topics: Aerosols; Allergens; Asthma; Child; Desensitization, Immunologic; Eczema; Female; Histamine; Humans; | 1969 |
[Changes in the histaminopexic capacity of the blood serum of patients with bronchial asthma under the effect of treatment].
Topics: Asthma; Blood Proteins; Histamine; Humans; Prednisolone | 1969 |
[Counterindications of various drugs in bronchial asthma].
Topics: Asthma; Cholinesterase Inhibitors; Female; Histamine; Humans; Male; Middle Aged; Parasympathomimetic | 1969 |
Serotonin (5-hydroxytryptamine) inhalation in patients with chronic non-specific lung disease.
Topics: Adolescent; Adult; Aerosols; Asthma; Bronchial Spasm; Bronchitis; Chronic Disease; Creatinine; Femal | 1969 |
Value of inhalation tests in bronchial asthma.
Topics: Aerosols; Allergens; Antigen-Antibody Reactions; Asthma; Bronchi; Bronchial Diseases; Dust; Eosinoph | 1969 |
[Symposium on asthma. Pathophysiology of lung in asthmatic attack. From the veiwpoint of changes of regional pulmonary function of changes of regional pulmonary function and the absorptive function of the bronchial wall].
Topics: Animals; Asthma; Bronchi; Bronchography; Dogs; Histamine; Humans; Lung; Pulmonary Artery; Radionucli | 1969 |
The histamine binding power (histaminopexy) of serum from healthy and asthmatic children.
Topics: Adolescent; Animals; Asthma; Blood; Child; Child, Preschool; Guinea Pigs; Histamine; Humans; In Vitr | 1969 |
A trial of assessment of the role of thyroid hormone in allergic conditions in children.
Topics: Adolescent; Adrenal Cortex Hormones; Asthma; Child; Child, Preschool; Dermatitis, Atopic; Drug Antag | 1969 |
The distribution of histamine in the blood of healthy and asthmatic children.
Topics: Adolescent; Asthma; Basophils; Child; Child, Preschool; Eosinophils; Histamine; Humans; Leukocyte Co | 1970 |
Eosinophilic peritonitis in a child. Report of studies made ten years later.
Topics: Asthma; Child; Eosinophilia; Histamine; Humans; Male; Peritonitis; Serotonin | 1970 |
Resistance to breathing during exercise-induced asthma attacks.
Topics: Adolescent; Adult; Aerosols; Airway Resistance; Asthma; Atropine; Bronchial Spasm; Carbon Dioxide; F | 1970 |
The effect of intravenous histamine on specific airway conductance in patients with airway obstruction and in normal subjects.
Topics: Adolescent; Adult; Asthma; Bronchitis; Child; Diagnosis, Differential; Female; Histamine; Humans; Ma | 1970 |
Effects of corticosteroids on distribution of histamine in the blood of asthmatic children.
Topics: Adrenal Cortex Hormones; Asthma; Basophils; Child; Eosinophils; Histamine; Humans; Leukocyte Count; | 1970 |
5,5-diphenyl-2-(2'-piperidinoethyl)-1,3-dioxolane-4-one a new drug with potent spasmolytic activity.
Topics: Acetylcholine; Animals; Asthma; Atropine; Barium; Blood Pressure; Blood Vessels; Carbachol; Cats; Ch | 1970 |
[Several biochemical studies in patients with infectious-allergic forms of bronchial asthma].
Topics: Adolescent; Adult; Aged; Asthma; C-Reactive Protein; Female; Histamine; Humans; Infections; Male; Mi | 1970 |
[Unspecific sensitivity in asthma, rhinitis and atopic dermatitis].
Topics: Acetylcholine; Asthma; Bronchial Spasm; Cardiovascular System; Dermatitis, Atopic; Histamine; Humans | 1970 |
[The antiallergic activity of tritoqualine].
Topics: Anaphylaxis; Animals; Asthma; Barium; Benzofurans; Gastric Juice; Guinea Pigs; Heart; Histamine; Ile | 1970 |
A study of Prausnitz-Küstner reaction in leprosy.
Topics: Allergens; Asthma; Histamine; Humans; Immunoglobulin E; Leprosy; Skin; Skin Tests; Tubocurarine | 1971 |
[Basophile leukocytes and histamine in blood in childhood diseases caused by allergic reactions].
Topics: Asthma; Basophils; Biological Assay; Child; Child, Preschool; Drug Hypersensitivity; Eczema; Food Hy | 1967 |
[The latex-histamine test in bronchial asthma].
Topics: Asthma; Histamine; Humans; Latex; Microspheres; Respiratory Hypersensitivity | 1967 |
[Experimental studies on the ciliary motility of the brachial epithelium in bronchial asthma. 2].
Topics: Acetylcholine; Animals; Asthma; Bronchi; Cilia; Epithelium; Guinea Pigs; Histamine; In Vitro Techniq | 1967 |
Bronchial hypersensitivity to mecholyl and histamine in asthma subjects.
Topics: Adolescent; Adult; Aged; Antigen-Antibody Reactions; Asthma; Female; Histamine; Humans; Hypersensiti | 1967 |
Intolerance to aspirin. Clinical studies and consideration of its pathogenesis.
Topics: Adult; Age Factors; Allergens; Angioedema; Aspirin; Asthma; Chemical Phenomena; Chemistry; Drug Hype | 1968 |
Blood histamine in certain allergic states.
Topics: Ancylostomiasis; Ascariasis; Asthma; Blood Cell Count; Bronchial Diseases; Eosinophilia; Eosinophils | 1968 |
Comparison of the effects of some drugs on guinea pigs at high altitudes and at sea level.
Topics: Altitude; Animals; Asthma; Cyanides; Epinephrine; Ethanol; Female; Guinea Pigs; Histamine; Male; Pen | 1968 |
[Evaluation of the bronchomotor activity of 5-hydroxytryptamine (5HT) in normal and asthmatic subjects].
Topics: Adult; Aerosols; Antigen-Antibody Reactions; Asthma; Bronchi; Histamine; Humans; Lung; Manometry; Me | 1968 |
[Studies on respiratory sensitivity of asthmatic patients. 2. Correlation of respiratory sensitivity and clinical factors].
Topics: Acetylcholine; Age Factors; Asthma; Desensitization, Immunologic; Female; Histamine; Humans; Male; R | 1968 |
[Studies on histaminopexy and serotoninopexy in normal and asthmatic children].
Topics: Adolescent; Asthma; Child; Child, Preschool; Female; Globins; Histamine; Humans; Male; Serotonin; Ti | 1968 |
Biochemical studies in bronchial asthma in infancy and childhood.
Topics: Asthma; Blood Protein Electrophoresis; Child; Child, Preschool; Electrocardiography; Eosinophils; Fe | 1968 |
[Studies of chronic urti caria. Constitutional difference between atopic and psycho-somatic types].
Topics: Adult; Asthma; Body Constitution; Chronic Disease; Female; Histamine; Humans; Male; Middle Aged; p-M | 1968 |
[Sensitivity of pediatric bronchial asthma and allergic bronchitis (pre-bronchial asthma stage) to histamine].
Topics: Adolescent; Adult; Antigen-Antibody Reactions; Asthma; Bronchitis; Child; Child, Preschool; Female; | 1968 |
[Study on bronchial hypersensitivity in experimental animals. 2. Evaluation of the bronchial reaction to histamine and acetylcholine during sensitization, induction of allergic reaction and desensitization processes].
Topics: Acetylcholine; Allergens; Animals; Asthma; Bronchi; Desensitization, Immunologic; Female; Guinea Pig | 1969 |
[Studies on bronchial hypersensitivity in asthmatic patients. I. Evaluation of hypersensitivity threshold by inhalation of acetylcholine, histamine and serotonin].
Topics: Acetylcholine; Asthma; Bronchi; Histamine; Humans; Serotonin | 1965 |
Acetylcholine and histamine bronchial sensitivity among rhinitis patients.
Topics: Acetylcholine; Adolescent; Adult; Asthma; Bronchi; Female; Histamine; Humans; Male; Middle Aged; Rhi | 1965 |
Childhood status asthmaticus. Recent clinical and laboratory observations and their application in treatment.
Topics: Acid-Base Equilibrium; Adolescent; Adrenal Cortex Hormones; Asthma; Blood; Blood Chemical Analysis; | 1966 |
Bronchial response to beta-adrenergic blockade.
Topics: Adolescent; Adult; Asthma; Bronchi; Female; Histamine; Humans; Hypersensitivity; Injections, Intrave | 1966 |
The effect of carotid body removal on artificially induced bronchospasm simulating asthma. An experimental study.
Topics: Aerosols; Animals; Asthma; Bronchial Spasm; Carotid Body; Guinea Pigs; Histamine; Psychosomatic Medi | 1966 |
[Quantitative inhalation test with acetylcholine and histamine in bronchial asthma. (Respiratory tract reaction to acetylcholine and histamine with special emphasis on the relationship to asthmatic conditons)].
Topics: Acetylcholine; Adolescent; Adult; Aerosols; Aged; Asthma; Bronchi; Female; Histamine; Humans; Male; | 1966 |
[Pathological findings and histamine content in the resected lung of a patient with bronchial asthma].
Topics: Adult; Asthma; Histamine; Humans; Lung; Male; Pneumonectomy; Tuberculosis, Pulmonary | 1966 |
[Studies on bronchial hypersensitivity in experimental animals. 1. Fundamental study on the bronchial hypersensitivity to acetylcholine and histamine].
Topics: Acetylcholine; Aerosols; Animals; Asthma; Body Weight; Bronchi; Circadian Rhythm; Female; Guinea Pig | 1966 |
[Studies on the threshold of intracutaneous reaction for house dust antigen in asthma patients and on the Prausnitz-Kuestner reaction].
Topics: Adolescent; Adult; Antibodies; Asthma; Child; Desensitization, Immunologic; Dust; Female; Histamine; | 1966 |
Lung tissue resistance in normal and asthmatic subjects.
Topics: Adolescent; Adult; Asthma; Female; Histamine; Humans; Lung; Male; Middle Aged; Sputum; Viscosity | 1966 |
[Correlation between the number of basophilic granulocytes and histamine concentration in the blood of asthmatic patients].
Topics: Adult; Asthma; Basophils; Blood Cell Count; Histamine; Humans | 1966 |
[On measuring bronchial resistance with a body plethysmograph].
Topics: Adult; Aerosols; Allergens; Asthma; Female; Histamine; Humans; Isoproterenol; Lung Diseases; Male; O | 1966 |