Page last updated: 2024-10-18

histamine and Amyotrophic Lateral Sclerosis

histamine has been researched along with Amyotrophic Lateral Sclerosis in 9 studies

Amyotrophic Lateral Sclerosis: A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94)

Research Excerpts

ExcerptRelevanceReference
"Histamine is an immune modulator, neuroprotective, and remyelinating agent, beneficially acting on skeletal muscles and promoting anti-inflammatory features in amyotrophic lateral sclerosis (ALS) microglia."9.01Histaminergic transmission slows progression of amyotrophic lateral sclerosis. ( Amadio, S; Apolloni, S; Cavallaro, S; Fabbrizio, P; Ferri, A; Latagliata, EC; Madaro, L; Morello, G; Proietti, D; Puglisi-Allegra, S; Salvatori, I; Spampinato, AG; Volonté, C, 2019)
"Histamine is an immune modulator, neuroprotective, and remyelinating agent, beneficially acting on skeletal muscles and promoting anti-inflammatory features in amyotrophic lateral sclerosis (ALS) microglia."5.01Histaminergic transmission slows progression of amyotrophic lateral sclerosis. ( Amadio, S; Apolloni, S; Cavallaro, S; Fabbrizio, P; Ferri, A; Latagliata, EC; Madaro, L; Morello, G; Proietti, D; Puglisi-Allegra, S; Salvatori, I; Spampinato, AG; Volonté, C, 2019)
"Hydrogen-rich water has a significant protective effect on OGD/R-causing HT22 cell injury, and the mechanism may be related to the inhibition of autophagy."4.40Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19. ( , 2023)
"Histamine was provided to primary microglia and NSC-34 motor neurons expressing the SOD1-G93A mutation."1.51Histamine Is an Inducer of the Heat Shock Response in SOD1-G93A Models of ALS. ( Amadio, S; Ammassari-Teule, M; Apolloni, S; Caputi, F; Fabbrizio, P; Pignataro, A; Volonté, C, 2019)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19901 (11.11)18.7374
1990's1 (11.11)18.2507
2000's0 (0.00)29.6817
2010's4 (44.44)24.3611
2020's3 (33.33)2.80

Authors

AuthorsStudies
Iida, T1
Yanai, K1
Yoshikawa, T1
Volonté, C5
Morello, G2
Spampinato, AG2
Amadio, S3
Apolloni, S5
D'Agata, V1
Cavallaro, S2
Fabbrizio, P2
Latagliata, EC1
Salvatori, I1
Proietti, D1
Ferri, A1
Madaro, L1
Puglisi-Allegra, S1
Sabatelli, M1
Caputi, F1
Pignataro, A1
Ammassari-Teule, M1
Parisi, C1
Nakamura, S1
Ohnishi, K1
Nishimura, M1
Suenaga, T1
Akiguchi, I1
Kimura, J1
Kimura, T1
Mawatari, S1
Takagi, A1
Rowland, LP1

Reviews

6 reviews available for histamine and Amyotrophic Lateral Sclerosis

ArticleYear
Histamine and Microglia.
    Current topics in behavioral neurosciences, 2022, Volume: 59

    Topics: Amyotrophic Lateral Sclerosis; Animals; Brain; Cytokines; Histamine; Humans; Microglia

2022
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Omics-based exploration and functional validation of neurotrophic factors and histamine as therapeutic targets in ALS.
    Ageing research reviews, 2020, Volume: 62

    Topics: Amyotrophic Lateral Sclerosis; Biomarkers; Histamine; Humans; Nerve Growth Factors; Prognosis

2020
Histaminergic transmission slows progression of amyotrophic lateral sclerosis.
    Journal of cachexia, sarcopenia and muscle, 2019, Volume: 10, Issue:4

    Topics: Amyotrophic Lateral Sclerosis; Animals; Disease Models, Animal; Disease Progression; Gene Expression

2019
Histamine beyond its effects on allergy: Potential therapeutic benefits for the treatment of Amyotrophic Lateral Sclerosis (ALS).
    Pharmacology & therapeutics, 2019, Volume: 202

    Topics: Amyotrophic Lateral Sclerosis; Animals; Histamine; Humans; Hypersensitivity; Immunologic Factors; Mo

2019
New kid on the block: does histamine get along with inflammation in amyotrophic lateral sclerosis?
    CNS & neurological disorders drug targets, 2015, Volume: 14, Issue:5

    Topics: Amyotrophic Lateral Sclerosis; Animals; Anti-Inflammatory Agents; Cytokines; Histamine; Humans; Infl

2015

Trials

1 trial available for histamine and Amyotrophic Lateral Sclerosis

ArticleYear
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023

Other Studies

3 other studies available for histamine and Amyotrophic Lateral Sclerosis

ArticleYear
Histamine Is an Inducer of the Heat Shock Response in SOD1-G93A Models of ALS.
    International journal of molecular sciences, 2019, Aug-03, Volume: 20, Issue:15

    Topics: Amyotrophic Lateral Sclerosis; Animals; Astrocytes; Cell Death; Dendritic Spines; Disease Models, An

2019
Large neurons in the tuberomammillary nucleus in patients with Parkinson's disease and multiple system atrophy.
    Neurology, 1996, Volume: 46, Issue:6

    Topics: Aged; Aged, 80 and over; Amyotrophic Lateral Sclerosis; Brain Chemistry; Cell Size; Female; Histamin

1996
Adenyl cyclase in normal and pathologic human muscle.
    Archives of neurology, 1974, Volume: 30, Issue:1

    Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Adenylyl Cyclases; Amyotrophic Lateral Sclerosis;

1974