histamine has been researched along with Allergy, Milk in 16 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| " Local anaphylactic reaction was evaluated by assaying histamine in faecal samples." | 3.73 | Peanut- and cow's milk-specific IgE, Th2 cells and local anaphylactic reaction are induced in Balb/c mice orally sensitized with cholera toxin. ( Adel-Patient, K; Ah-Leung, S; Bernard, H; Créminon, C; Wal, JM, 2005) |
| " Intragastric challenge with CM at week 6 elicited systemic anaphylaxis accompanied by vascular leakage, significantly increased plasma histamine, and increased intestinal permeability to casein." | 3.70 | A murine model of IgE-mediated cow's milk hypersensitivity. ( Huang, CK; Kleiner, GI; Li, XM; Sampson, HA; Schofield, BH, 1999) |
| "Systemic anaphylaxis is a severe hypersensitive allergic reaction resulting from degranulation of mast cells or basophils after cross-linking of surface high-affinity IgE receptors (Fcε-RI) with allergen-specific IgE and allergens." | 1.62 | Bovine β-lactoglobulin-induced passive systemic anaphylaxis model using humanized NOG hIL-3/hGM-CSF transgenic mice. ( Ito, M; Ito, R; Katano, I; Otsuka, I; Simons, PJ; Suemizu, H; Takahashi, T, 2021) |
| "In this work, we used a food allergy model in BALB/c mice to study the cross-reactivity between cow's milk protein (CMP) and soy proteins (SP)." | 1.38 | In vivo evidence of cross-reactivity between cow's milk and soybean proteins in a mouse model of food allergy. ( Candreva, A; Curciarello, R; Docena, GH; Fossati, CA; Petruccelli, S; Rey, MA; Smaldini, P, 2012) |
| "Cow's milk allergy is quite common in the first years of human life." | 1.33 | The balance between caseins and whey proteins in cow's milk determines its allergenicity. ( Lara-Villoslada, F; Olivares, M; Xaus, J, 2005) |
| " In some individual dose-response curves, the scores obtained by HRM were shifted to higher allergen and anti-IgE concentrations." | 1.29 | Comparison of fiberglass-based histamine assay with a conventional automated fluorometric histamine assay, case history, skin prick test, and specific serum IgE in patients with milk and egg allergic reactions. ( Kleine-Tebbe, J; Kunkel, G; Nolte, H; Roedsgaard, D; Skov, PS; Wahn, U; Werfel, S, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (18.75) | 18.2507 |
| 2000's | 6 (37.50) | 29.6817 |
| 2010's | 4 (25.00) | 24.3611 |
| 2020's | 3 (18.75) | 2.80 |
| Authors | Studies |
|---|---|
| Ito, R | 1 |
| Katano, I | 1 |
| Otsuka, I | 1 |
| Takahashi, T | 1 |
| Suemizu, H | 1 |
| Ito, M | 1 |
| Simons, PJ | 1 |
| Germundson, DL | 1 |
| Vendsel, LP | 1 |
| Nagamoto-Combs, K | 1 |
| Duan, C | 1 |
| Ma, L | 1 |
| Cai, L | 1 |
| Li, X | 1 |
| Ma, F | 1 |
| Chen, J | 1 |
| Huo, G | 1 |
| Li, D | 1 |
| Frischmeyer-Guerrerio, PA | 2 |
| Masilamani, M | 1 |
| Gu, W | 1 |
| Brittain, E | 1 |
| Wood, R | 1 |
| Kim, J | 1 |
| Nadeau, K | 1 |
| Jarvinen, KM | 1 |
| Grishin, A | 1 |
| Lindblad, R | 1 |
| Sampson, HA | 2 |
| Morisawa, Y | 1 |
| Kitamura, A | 1 |
| Ujihara, T | 1 |
| Zushi, N | 1 |
| Kuzume, K | 1 |
| Shimanouchi, Y | 1 |
| Tamura, S | 1 |
| Wakiguchi, H | 1 |
| Saito, H | 1 |
| Matsumoto, K | 1 |
| Keet, CA | 1 |
| Thyagarajan, A | 1 |
| Schroeder, JT | 1 |
| Hamilton, RG | 1 |
| Boden, S | 1 |
| Steele, P | 1 |
| Driggers, S | 1 |
| Burks, AW | 1 |
| Wood, RA | 1 |
| Smaldini, P | 1 |
| Curciarello, R | 1 |
| Candreva, A | 1 |
| Rey, MA | 1 |
| Fossati, CA | 1 |
| Petruccelli, S | 1 |
| Docena, GH | 1 |
| Bailón, E | 1 |
| Cueto-Sola, M | 1 |
| Utrilla, P | 1 |
| Rodríguez-Ruiz, J | 1 |
| Garrido-Mesa, N | 1 |
| Zarzuelo, A | 1 |
| Xaus, J | 3 |
| Gálvez, J | 1 |
| Comalada, M | 1 |
| Osterballe, M | 1 |
| Andersen, KE | 1 |
| Bindslev-Jensen, C | 1 |
| Lara-Villoslada, F | 2 |
| Olivares, M | 2 |
| Jiménez, J | 1 |
| Boza, J | 1 |
| Adel-Patient, K | 1 |
| Bernard, H | 1 |
| Ah-Leung, S | 1 |
| Créminon, C | 1 |
| Wal, JM | 1 |
| Kitagawa, S | 1 |
| Zhang, S | 1 |
| Harari, Y | 1 |
| Castro, GA | 1 |
| Kleine-Tebbe, J | 1 |
| Werfel, S | 1 |
| Roedsgaard, D | 1 |
| Nolte, H | 1 |
| Skov, PS | 1 |
| Wahn, U | 1 |
| Kunkel, G | 1 |
| Li, XM | 1 |
| Schofield, BH | 1 |
| Huang, CK | 1 |
| Kleiner, GI | 1 |
| Poonyachoti, S | 1 |
| Brown, DR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase II Study of Baked Milk Oral Immunotherapy for the Treatment of Cow's Milk Allergy[NCT03462030] | Phase 2 | 41 participants (Actual) | Interventional | 2018-03-15 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Adverse events will be recorded per CTCAE version 4.0. Events per dose on baked milk oral immunotherapy will be compared to adverse events per dose on placebo. Data will be collected over the first year of treatment. Analysis of cumulative adverse reactions per dose of oral immunotherapy or placebo will be performed at the end of year 1. (NCT03462030)
Timeframe: 1 year
| Intervention | Participants (Count of Participants) |
|---|---|
| Baked Milk Immunotherapy | 15 |
| Placebo | 11 |
The investigators will perform baked milk challenges to 4044 mg of baked milk protein and calculate the proportion of subjects who tolerate 4 grams of baked milk protein after one year of baked milk oral immunotherapy. This measure reports the number of participants that were able to tolerate 4 grams of baked milk protein. (NCT03462030)
Timeframe: 1 year
| Intervention | Participants (Count of Participants) |
|---|---|
| Baked Milk Immunotherapy | 11 |
| Placebo | 0 |
3 trials available for histamine and Allergy, Milk
| Article | Year |
|---|---|
Mechanistic correlates of clinical responses to omalizumab in the setting of oral immunotherapy for milk allergy.
Topics: Administration, Oral; Adolescent; Adult; Allergens; Anti-Allergic Agents; Basophils; Caseins; Cell P | 2017 |
The safety and efficacy of sublingual and oral immunotherapy for milk allergy.
Topics: Administration, Oral; Administration, Sublingual; Adolescent; Basophils; Child; Desensitization, Imm | 2012 |
The diagnostic accuracy of the atopy patch test in diagnosing hypersensitivity to cow's milk and hen's egg in unselected children with and without atopic dermatitis.
Topics: Basophils; Child, Preschool; Dermatitis, Atopic; Egg Hypersensitivity; Histamine; Humans; Milk Hyper | 2004 |
13 other studies available for histamine and Allergy, Milk
| Article | Year |
|---|---|
Bovine β-lactoglobulin-induced passive systemic anaphylaxis model using humanized NOG hIL-3/hGM-CSF transgenic mice.
Topics: Anaphylaxis; Animals; Basophils; Cattle; Disease Models, Animal; Epinephrine; Granulocyte-Macrophage | 2021 |
Region-specific regulation of central histaminergic H3 receptor expression in a mouse model of cow's milk allergy.
Topics: Animals; Brain; Disease Models, Animal; Female; Gene Expression Regulation; Histamine; Intestine, Sm | 2020 |
Comparison of allergenicity among cow, goat, and horse milks using a murine model of atopy.
Topics: Administration, Oral; Allergens; Animals; Cattle; Cytokines; Disease Models, Animal; Female; Goats; | 2021 |
Effect of heat treatment and enzymatic digestion on the B cell epitopes of cow's milk proteins.
Topics: Adolescent; Allergens; Animals; Basophils; Caseins; Child; Child, Preschool; Epitopes, B-Lymphocyte; | 2009 |
In vivo evidence of cross-reactivity between cow's milk and soybean proteins in a mouse model of food allergy.
Topics: Animals; Cross Reactions; Cytokines; Disease Models, Animal; Food Hypersensitivity; Histamine; Immun | 2012 |
A shorter and more specific oral sensitization-based experimental model of food allergy in mice.
Topics: Administration, Oral; Animals; Cattle; Cholera Toxin; Diarrhea; Disease Models, Animal; Enzyme-Linke | 2012 |
Goat milk is less immunogenic than cow milk in a murine model of atopy.
Topics: Administration, Oral; Allergens; Animals; Cattle; Cell Division; Cells, Cultured; Cytokines; Diarrhe | 2004 |
Peanut- and cow's milk-specific IgE, Th2 cells and local anaphylactic reaction are induced in Balb/c mice orally sensitized with cholera toxin.
Topics: Anaphylaxis; Animals; Antibody Specificity; Arachis; Cholera Toxin; Cytokines; Feces; Female; Histam | 2005 |
The balance between caseins and whey proteins in cow's milk determines its allergenicity.
Topics: Animals; Caseins; Cattle; Female; Histamine; Immunoglobulin G; Lactoglobulins; Mice; Mice, Inbred BA | 2005 |
Relative allergenicity of cow's milk and cow's milk-based formulas in an animal model.
Topics: Allergens; Anaphylaxis; Animals; Bronchial Spasm; Calcium Channel Blockers; Cattle; Chloride Channel | 1995 |
Comparison of fiberglass-based histamine assay with a conventional automated fluorometric histamine assay, case history, skin prick test, and specific serum IgE in patients with milk and egg allergic reactions.
Topics: Adolescent; Adult; Basophils; Child; Child, Preschool; Dose-Response Relationship, Immunologic; Eggs | 1993 |
A murine model of IgE-mediated cow's milk hypersensitivity.
Topics: Adjuvants, Immunologic; Anaphylaxis; Animals; Capillary Permeability; Caseins; Cell Degranulation; C | 1999 |
delta-opioid receptors inhibit neurogenic intestinal secretion evoked by mast cell degranulation and type I hypersensitivity.
Topics: Animals; Biological Transport; Cell Degranulation; Enkephalin, D-Penicillamine (2,5)-; Female; Hista | 2001 |