histamine has been researched along with Allergic Conjunctivitis in 80 studies
Excerpt | Relevance | Reference |
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"The objective of this review was to assess the effects of topical antihistamines and mast cell stabilisers, alone or in combination, for use in treating seasonal and perennial allergic conjunctivitis." | 8.91 | Topical antihistamines and mast cell stabilisers for treating seasonal and perennial allergic conjunctivitis. ( Azuara-Blanco, A; Castillo, M; Mustafa, MS; Mustafa, MZ; Scott, NW, 2015) |
"The aim of the current study was to investigate whether olopatadine and naphazoline hydrochloride reduce allergic conjunctivitis in mice through alterations in inflammation, NGF and VEGF." | 7.83 | Treatment with olopatadine and naphazoline hydrochloride reduces allergic conjunctivitis in mice through alterations in inflammation, NGF and VEGF. ( He, H; Quan, L, 2016) |
" The aim of this study was to evaluate the effects of TQ on ovalbumin (OVA)-induced allergic conjunctivitis (AC) in Balb/c." | 7.77 | Ameliorative effect of thymoquinone on ovalbumin-induced allergic conjunctivitis in Balb/c mice. ( Asim, MB; Hayat, K; Li, M; Nawaz, M; Sun, N; Zhang, L, 2011) |
"To elucidate the ocular pharmacological properties of bepotastine besilate, a selective histamine H(1) receptor antagonist, when compared with other histamine H(1) receptor antagonists, using guinea pig allergic conjunctivitis models and in vitro models of eosinophil recruitment and mast cell membrane stabilization." | 7.76 | Bepotastine besilate, a highly selective histamine H(1) receptor antagonist, suppresses vascular hyperpermeability and eosinophil recruitment in in vitro and in vivo experimental allergic conjunctivitis models. ( Atsumi, I; Fujii, A; Iemura, M; Kida, T; Sakai, O; Sakaki, H; Wada, T, 2010) |
"Six allergic conjunctivitis patients (12 eyes) and 4 healthy volunteers (8 eyes) were investigated in terms of the effect of cooling sheets on eye itching and tear histamine concentration, before and 5 min after cooling the eyelids with cooling sheets." | 7.76 | Relation between cooling sheet effect and tear histamine concenration in allergic conjunctivitis. ( Hirakawa, N; Yano, H; Yanoshita, R; Yoshii, M, 2010) |
"We investigated the character of histamine H(1) receptor and H(4) receptor in allergic conjunctivitis." | 7.75 | Role of histamine H(4) receptor in allergic conjunctivitis in mice. ( Kagawa, Y; Kamei, C; Kurata, Y; Nakano, Y; Ono, R; Takahashi, Y, 2009) |
"To clarify the role of histamine H1 receptors in allergic conjunctivitis, changes in vascular permeability of the conjunctiva were measured in histamine H1 receptor deficient mice." | 7.70 | Vascular permeability in allergic conjunctivitis in mice lacking histamine H1 receptors. ( Izushi, K; Kamei, C; Nakahara, H; Sugimoto, Y; Watanabe, T, 2000) |
"The role of substance P in experimental allergic conjunctivitis induced by egg albumin was investigated with guinea pigs." | 7.69 | Role of substance P in experimental allergic conjunctivitis in guinea pigs. ( Fujiwara, R; Izushi, K; Kamei, C; Ohishi, H; Sugimoto, Y; Takada, M; Yamaji, M, 1997) |
" At the same dose histamine skin reactions and at slightly higher doses passive cutaneous anaphylactic reactions are inhibited." | 7.68 | Levocabastine: pharmacological profile of a highly effective inhibitor of allergic reactions. ( Awouters, F; Jansen, T; Janssen, PA; Megens, AA; Niemegeers, CJ, 1992) |
"The effect of the ophthalmic solution of tranilast, an anti-allergic agent, on allergic conjunctivitis was studied in passively sensitized guinea pigs." | 7.68 | [Effect of tranilast ophthalmic solution on allergic conjunctivitis in guinea pigs]. ( Isaji, M; Itoh, F; Kojima, M; Komatsu, Y; Miyata, H; Momose, Y; Shibazaki, T; Suzawa, H; Taya, F, 1993) |
" Dose-response curves demonstrated that 0." | 6.67 | Allergic conjunctivitis: a survey of new antihistamines. ( Abelson, MB; Berdy, GJ; George, MA; Giovanoni, RL; Smith, LM, 1991) |
"The effects of histamine in allergic conjunctivitis are mediated by H1-receptor activation on blood vessels and nociceptive nerves." | 6.41 | Role of histamine in allergic conjunctivitis. ( Leonardi, A, 2000) |
"Ten patients with cedar pollen-allergic conjunctivitis and 10 patients with postsurgical conjunctivitis were enrolled in this study." | 5.29 | Measurement of interleukin-4 and histamine in superficial cells of conjunctiva in patients with allergic conjunctivitis. ( Fujishima, H; Saito, I; Shinozaki, N; Takeuchi, T; Tsubota, K, 1996) |
"The objective of this review was to assess the effects of topical antihistamines and mast cell stabilisers, alone or in combination, for use in treating seasonal and perennial allergic conjunctivitis." | 4.91 | Topical antihistamines and mast cell stabilisers for treating seasonal and perennial allergic conjunctivitis. ( Azuara-Blanco, A; Castillo, M; Mustafa, MS; Mustafa, MZ; Scott, NW, 2015) |
"In the elderly, H1-antihistamine therapy is commonly prescribed for treatment of rhinitis, conjunctivitis, pruritus, eczema, urticaria, and for prophylaxis of anaphylactoid reactions." | 4.81 | H1-antihistamines in the elderly. ( Kaliner, MA, 2002) |
" In this study, we developed epinastine hydrochloride-releasing daily soft contact lenses for treatment of allergic conjunctivitis and examined their in vitro and in vivo performance." | 3.91 | In vitro and in vivo performance of epinastine hydrochloride-releasing contact lenses. ( Arai, R; Fukushima, A; Hino, S; Ishida, W; Kishimoto, T; Matsunaga, T; Minami, T; Nakajima, I; Yamagami, S, 2019) |
"The aim of the current study was to investigate whether olopatadine and naphazoline hydrochloride reduce allergic conjunctivitis in mice through alterations in inflammation, NGF and VEGF." | 3.83 | Treatment with olopatadine and naphazoline hydrochloride reduces allergic conjunctivitis in mice through alterations in inflammation, NGF and VEGF. ( He, H; Quan, L, 2016) |
" They were able to inhibit the release of histamine and TNF-α from sensitized mast cells, proving their potential application in preventing and treating allergic conjunctivitis." | 3.83 | Biomimetic contact lenses eluting olopatadine for allergic conjunctivitis. ( Alvarez-Lorenzo, C; Concheiro, A; González-Chomón, C; Silva, M, 2016) |
" As resolvin (Rv) D1 is produced in the cornea, pro-resolution mediators could be effective in regulating inflammatory responses to histamine in allergic conjunctivitis." | 3.79 | Resolvin D1 and aspirin-triggered resolvin D1 regulate histamine-stimulated conjunctival goblet cell secretion. ( Carozza, RB; Chiang, N; Dartt, DA; Hodges, RR; Jiao, J; Li, D; Serhan, CN; Shatos, MA, 2013) |
" The aim of this study was to evaluate the effects of TQ on ovalbumin (OVA)-induced allergic conjunctivitis (AC) in Balb/c." | 3.77 | Ameliorative effect of thymoquinone on ovalbumin-induced allergic conjunctivitis in Balb/c mice. ( Asim, MB; Hayat, K; Li, M; Nawaz, M; Sun, N; Zhang, L, 2011) |
"Conjunctival oedema is commonly observed in patients with allergic conjunctivitis and can be induced by histamine." | 3.76 | Evaluation of histamine-induced conjunctival oedema in guinea pigs by means of image analysis. ( Fukushima, A; Kayasuga, A; Mibu, H; Shii, D; Sumi, T; Tada, K; Takahashi, A, 2010) |
"Six allergic conjunctivitis patients (12 eyes) and 4 healthy volunteers (8 eyes) were investigated in terms of the effect of cooling sheets on eye itching and tear histamine concentration, before and 5 min after cooling the eyelids with cooling sheets." | 3.76 | Relation between cooling sheet effect and tear histamine concenration in allergic conjunctivitis. ( Hirakawa, N; Yano, H; Yanoshita, R; Yoshii, M, 2010) |
"To elucidate the ocular pharmacological properties of bepotastine besilate, a selective histamine H(1) receptor antagonist, when compared with other histamine H(1) receptor antagonists, using guinea pig allergic conjunctivitis models and in vitro models of eosinophil recruitment and mast cell membrane stabilization." | 3.76 | Bepotastine besilate, a highly selective histamine H(1) receptor antagonist, suppresses vascular hyperpermeability and eosinophil recruitment in in vitro and in vivo experimental allergic conjunctivitis models. ( Atsumi, I; Fujii, A; Iemura, M; Kida, T; Sakai, O; Sakaki, H; Wada, T, 2010) |
"We investigated the character of histamine H(1) receptor and H(4) receptor in allergic conjunctivitis." | 3.75 | Role of histamine H(4) receptor in allergic conjunctivitis in mice. ( Kagawa, Y; Kamei, C; Kurata, Y; Nakano, Y; Ono, R; Takahashi, Y, 2009) |
" The levels of IL-4 and histamine in the specimens and mean IL-4 tear level were significantly increased in patients with allergic conjunctivitis." | 3.71 | Respiratory syncytial virus may be a pathogen in allergic conjunctivitis. ( Fujishima, H, 2002) |
"To clarify the role of histamine H1 receptors in allergic conjunctivitis, changes in vascular permeability of the conjunctiva were measured in histamine H1 receptor deficient mice." | 3.70 | Vascular permeability in allergic conjunctivitis in mice lacking histamine H1 receptors. ( Izushi, K; Kamei, C; Nakahara, H; Sugimoto, Y; Watanabe, T, 2000) |
"The classic clinical symptoms of allergic conjunctivitis (type I allergy)--itching and lacrimation--are the effect of histamine." | 3.70 | [Histamine in tears in allergic rhinoconjunctivitis]. ( Lautenschläger, C; Lübbe, D; Pönicke, K; Struck, HG; Wicht, A, 1998) |
"The role of substance P in experimental allergic conjunctivitis induced by egg albumin was investigated with guinea pigs." | 3.69 | Role of substance P in experimental allergic conjunctivitis in guinea pigs. ( Fujiwara, R; Izushi, K; Kamei, C; Ohishi, H; Sugimoto, Y; Takada, M; Yamaji, M, 1997) |
"The effect of the ophthalmic solution of tranilast, an anti-allergic agent, on allergic conjunctivitis was studied in passively sensitized guinea pigs." | 3.68 | [Effect of tranilast ophthalmic solution on allergic conjunctivitis in guinea pigs]. ( Isaji, M; Itoh, F; Kojima, M; Komatsu, Y; Miyata, H; Momose, Y; Shibazaki, T; Suzawa, H; Taya, F, 1993) |
" At the same dose histamine skin reactions and at slightly higher doses passive cutaneous anaphylactic reactions are inhibited." | 3.68 | Levocabastine: pharmacological profile of a highly effective inhibitor of allergic reactions. ( Awouters, F; Jansen, T; Janssen, PA; Megens, AA; Niemegeers, CJ, 1992) |
"Allergic conjunctivitis is highly prevalent and affects up to one third of the general population." | 2.82 | Neuropathic pain and itch: mechanisms in allergic conjunctivitis. ( Chisolm, S; Kalangara, JP; Kuruvilla, ME; Vanijcharoenkarn, K, 2022) |
"Tear histamine levels were significantly lower after challenge in the eyes pretreated with olopatadine compared with placebo (mean [SD], 7 [8] vs 22 [12] nmol/L; P = 0." | 2.71 | Double-masked, randomized, placebo-controlled clinical study of the mast cell-stabilizing effects of treatment with olopatadine in the conjunctival allergen challenge model in humans. ( Abelson, MB; Leonardi, A, 2003) |
"Nedocromil sodium treatment reduced tear concentrations of histamine (by 77%) and PGD(2) (by 70%) at 30 minutes after challenge (both P <." | 2.70 | Nedocromil sodium and levocabastine reduce the symptoms of conjunctival allergen challenge by different mechanisms. ( Ahluwalia, P; Anderson, DF; Church, MK; McGill, JI; Wilson, SJ, 2001) |
"Levocabastine eye-drops were well-tolerated and no adverse reactions to the study drug were reported." | 2.67 | Rapid onset of action of levocabastine eye-drops in histamine-induced conjunctivitis. ( Feinberg, G; Stokes, TC, 1993) |
" Dose-response curves demonstrated that 0." | 2.67 | Allergic conjunctivitis: a survey of new antihistamines. ( Abelson, MB; Berdy, GJ; George, MA; Giovanoni, RL; Smith, LM, 1991) |
" Moreover, the threshold concentration of histamine diphosphate, extrapolated from each individual dose-response curve, was significantly (p less than 0." | 2.67 | Conjunctival hyperresponsiveness to ocular histamine challenge in patients with vernal conjunctivitis. ( Allansmith, MR; Bonini, S; Bucci, MG; Centofanti, M; Schiavone, M, 1992) |
"Ocular allergy is a disorder affecting increasing numbers of individuals worldwide." | 2.46 | The role of histamine in ocular allergy. ( Fukuda, K; Manzouri, B; Morohoshi, K; Ohbayashi, M; Ono, SJ, 2010) |
"Histamine is a key mediator of the allergic immediate reaction." | 2.43 | [Oral second generation antihistamines in allergic rhinitis]. ( Riechelmann, H, 2005) |
"The effects of histamine in allergic conjunctivitis are mediated by H1-receptor activation on blood vessels and nociceptive nerves." | 2.41 | Role of histamine in allergic conjunctivitis. ( Leonardi, A, 2000) |
"Allergic conjunctivitis is the most common cause leading to ocular redness (OR)." | 1.72 | Therapeutic efficacy of topical blockade of substance P in experimental allergic red eye. ( Blanco, T; Chen, Y; Dana, R; Ge, H; Liu, L; Pang, K; Wang, S; Xia, Y, 2022) |
"Twenty children with allergic conjunctivitis (17 SAC, and 3 PAC) and sixteen healthy children were included in this study." | 1.37 | [Allergic mediators in tear from children with seasonal and perennial allergic conjunctivitis]. ( Acera, A; González, N; Martínez, R; Soria, J; Suárez, T, 2011) |
"After the onset of allergic conjunctivitis, both eyes were treated with topical olopatadine." | 1.37 | Pre-seasonal treatment with topical olopatadine suppresses the clinical symptoms of seasonal allergic conjunctivitis. ( Miyazawa, A; Nakazawa, T; Otani, T; Shimura, M; Yasuda, K, 2011) |
"The histamine level was also reduced by EPPF or RA administration in the serum of OVA-sensitized mice." | 1.37 | Effect of Perilla frutescens var. acuta Kudo and rosmarinic acid on allergic inflammatory reactions. ( Ahn, HJ; Kim, HM; Oh, HA; Park, CS; Park, YS, 2011) |
"In a Japanese cedar pollen-induced allergic conjunctivitis model in guinea pigs, symptoms were aggravated by repeated pollen challenges." | 1.35 | Effects of multiple dexamethasone treatments on aggravation of allergic conjunctivitis associated with mast cell hyperplasia. ( Fujii, M; Kohno, S; Mizutani, N; Nabe, T; Nagata, T, 2008) |
"We report a new experimental allergic conjunctivitis with Japanese cedar pollen as antigen in guinea pigs, and the immunological characteristics of this model were also elucidated." | 1.31 | Experimental allergic conjunctivitis in guinea pigs induced by Japanese cedar pollen. ( Izushi, K; Kamei, C; Nakahara, H; Sugimoto, Y; Takada, M; Yamada, T, 2000) |
"Tear histamine was measured in 10 allergic patients after allergen challenge." | 1.31 | Tear and serum soluble leukocyte activation markers in conjunctival allergic diseases. ( Borghesan, F; Depaoli, M; Faggian, D; Leonardi, A; Plebani, M; Secchi, AG, 2000) |
" Comparisons of relative potency 30 min post dosing between emedastine and other anti-histamines demonstrated that emedastine is equipotent to ketotifen, and 7, 7, 10, 10, 100, 357, 3333, and 5813 times more potent than brompheniramine, chlorpheniramine, clemastine, pyrilamine, levocabastine, pheniramine, diphenhydramine, and antazoline, respectively." | 1.29 | Preclinical efficacy of emedastine, a potent, selective histamine H1 antagonist for topical ocular use. ( Parnell, DW; Spellman, JM; Stephens, DJ; Yanni, JM, 1994) |
"Ten patients with cedar pollen-allergic conjunctivitis and 10 patients with postsurgical conjunctivitis were enrolled in this study." | 1.29 | Measurement of interleukin-4 and histamine in superficial cells of conjunctiva in patients with allergic conjunctivitis. ( Fujishima, H; Saito, I; Shinozaki, N; Takeuchi, T; Tsubota, K, 1996) |
"Histamine release was not stimulated by AL-4943A at concentrations as high as 10 mM." | 1.29 | The in vitro and in vivo ocular pharmacology of olopatadine (AL-4943A), an effective anti-allergic/antihistaminic agent. ( Brady, MT; Gamache, DA; Graff, G; Lang, LS; Miller, ST; Parnell, D; Spellman, JM; Stephens, DJ; Weimer, LK; Yanni, JM, 1996) |
"Histamine was measured by enzyme-linked immunosorbent assay in acid samples treated with perchloric to deactivate histaminase and in untreated samples." | 1.29 | Histaminase activity in patients with vernal keratoconjunctivitis. ( Abelson, MB; Fregona, IA; George, MA; Leonardi, AA; Secchi, AG; Smith, LM, 1995) |
"Levocabastine is a potent competitor against histamine for conjunctival H1 receptors and should prove a useful, possibly long-acting drug for the reversal of inflammatory conjunctivitis and inhibition of its recurrence." | 1.27 | Application of histamine-induced conjunctivitis to the assessment of a topical antihistamine, levocabastine. ( Feinberg, G; Stokes, TC, 1987) |
"Levocabastine (0." | 1.27 | Levocabastine. Evaluation in the histamine and compound 48/80 models of ocular allergy in humans. ( Abelson, MB; Smith, LM, 1988) |
"Indomethacin failed to inhibit either challenge." | 1.27 | The role of leukotriene D4 as a mediator of allergic conjunctivitis in the guinea-pig. ( Ford-Hutchinson, AW; Garceau, D, 1987) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 7 (8.75) | 18.7374 |
1990's | 23 (28.75) | 18.2507 |
2000's | 20 (25.00) | 29.6817 |
2010's | 26 (32.50) | 24.3611 |
2020's | 4 (5.00) | 2.80 |
Authors | Studies |
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Sharif, NA | 3 |
Kalangara, JP | 1 |
Vanijcharoenkarn, K | 1 |
Chisolm, S | 1 |
Kuruvilla, ME | 1 |
Wang, S | 1 |
Liu, L | 1 |
Blanco, T | 1 |
Ge, H | 1 |
Xia, Y | 1 |
Pang, K | 1 |
Chen, Y | 1 |
Dana, R | 1 |
Bao, J | 1 |
Zhang, P | 1 |
Wu, B | 1 |
Wang, J | 1 |
Li, S | 1 |
Li, A | 1 |
Jie, Y | 1 |
Heidinger, A | 1 |
Rabensteiner, DF | 1 |
Rabensteiner, J | 1 |
Kieslinger, P | 1 |
Horwath-Winter, J | 1 |
Stabentheiner, E | 1 |
Riedl, R | 1 |
Wedrich, A | 1 |
Schmut, O | 1 |
Mello-Bosnic, C | 1 |
Gimenes, AD | 1 |
Oliani, SM | 1 |
Gil, CD | 1 |
García-Posadas, L | 1 |
Hodges, RR | 3 |
Diebold, Y | 1 |
Dartt, DA | 3 |
Minami, T | 1 |
Ishida, W | 1 |
Kishimoto, T | 1 |
Nakajima, I | 1 |
Hino, S | 1 |
Arai, R | 1 |
Matsunaga, T | 1 |
Fukushima, A | 2 |
Yamagami, S | 1 |
Li, D | 2 |
Jiao, J | 1 |
Carozza, RB | 1 |
Shatos, MA | 1 |
Chiang, N | 1 |
Serhan, CN | 1 |
Nabe, T | 2 |
Kijitani, Y | 1 |
Kitagawa, Y | 1 |
Sakano, E | 1 |
Ueno, T | 1 |
Fujii, M | 2 |
Nakao, S | 1 |
Sakai, M | 1 |
Takai, S | 1 |
Pozharitskaya, ON | 1 |
Shikov, AN | 1 |
Makarova, MN | 1 |
Ivanova, SA | 1 |
Kosman, VM | 1 |
Makarov, VG | 1 |
Bazgier, V | 1 |
Berka, K | 1 |
Otyepka, M | 1 |
Ulrichová, J | 1 |
Su, W | 1 |
Wan, Q | 1 |
Huang, J | 1 |
Han, L | 1 |
Chen, X | 1 |
Chen, G | 1 |
Olsen, N | 1 |
Zheng, SG | 1 |
Liang, D | 1 |
Castillo, M | 1 |
Scott, NW | 1 |
Mustafa, MZ | 1 |
Mustafa, MS | 1 |
Azuara-Blanco, A | 1 |
Huang, CC | 1 |
Kim, YS | 1 |
Olson, WP | 1 |
Li, F | 1 |
Guo, C | 1 |
Luo, W | 1 |
Huang, AJW | 1 |
Liu, Q | 1 |
Li, T | 1 |
Zhao, C | 1 |
Quan, L | 1 |
He, H | 1 |
González-Chomón, C | 1 |
Silva, M | 1 |
Concheiro, A | 1 |
Alvarez-Lorenzo, C | 1 |
Tagawa, Y | 1 |
Namba, K | 1 |
Nakazono, Y | 1 |
Iwata, D | 1 |
Ishida, S | 1 |
Nakano, Y | 1 |
Takahashi, Y | 1 |
Ono, R | 1 |
Kurata, Y | 1 |
Kagawa, Y | 1 |
Kamei, C | 7 |
Lambiase, A | 1 |
Micera, A | 1 |
Bonini, S | 3 |
Kida, T | 1 |
Fujii, A | 1 |
Sakai, O | 1 |
Iemura, M | 1 |
Atsumi, I | 1 |
Wada, T | 1 |
Sakaki, H | 1 |
Hirakawa, N | 1 |
Yanoshita, R | 1 |
Yoshii, M | 1 |
Yano, H | 1 |
Takahashi, A | 1 |
Sumi, T | 1 |
Tada, K | 1 |
Mibu, H | 1 |
Shii, D | 1 |
Kayasuga, A | 1 |
Oh, HA | 1 |
Park, CS | 1 |
Ahn, HJ | 1 |
Park, YS | 1 |
Kim, HM | 1 |
Shimura, M | 1 |
Yasuda, K | 1 |
Miyazawa, A | 1 |
Otani, T | 1 |
Nakazawa, T | 1 |
Hayat, K | 1 |
Asim, MB | 1 |
Nawaz, M | 1 |
Li, M | 1 |
Zhang, L | 1 |
Sun, N | 1 |
Ohbayashi, M | 1 |
Manzouri, B | 1 |
Morohoshi, K | 1 |
Fukuda, K | 1 |
Ono, SJ | 1 |
Martínez, R | 1 |
Acera, A | 1 |
Soria, J | 1 |
González, N | 1 |
Suárez, T | 1 |
Hayashi, D | 1 |
Hayashi, C | 1 |
Shatos, M | 1 |
Andoh, T | 1 |
Sakai, K | 1 |
Urashima, M | 1 |
Kitazawa, K | 1 |
Honma, A | 1 |
Kuraishi, Y | 1 |
Callebaut, I | 1 |
Vandewalle, E | 1 |
Hox, V | 1 |
Bobic, S | 1 |
Jorissen, M | 1 |
Stalmans, I | 1 |
De Vries, A | 1 |
Scadding, G | 1 |
Hellings, PW | 1 |
Wade, L | 1 |
Bielory, L | 1 |
Rudner, S | 1 |
Howarth, P | 1 |
Kaliner, MA | 1 |
Leonardi, A | 5 |
Abelson, MB | 4 |
Hashimoto, T | 1 |
Igarashi, A | 1 |
Hoshina, F | 1 |
Yamada, M | 1 |
Toyoda, Y | 1 |
Notsu, Y | 1 |
Kohno, S | 2 |
LINNEN, HJ | 1 |
Minami, K | 1 |
Takano, H | 1 |
Osakabe, N | 1 |
Sanbongi, C | 1 |
Yanagisawa, R | 1 |
Inoue, K | 1 |
Yasuda, A | 1 |
Natsume, M | 1 |
Baba, S | 1 |
Ichiishi, E | 1 |
Yoshikawa, T | 1 |
Simons, FE | 1 |
Riechelmann, H | 1 |
Kirmaz, C | 1 |
Yuksel, H | 1 |
Mete, N | 1 |
Bayrak, P | 1 |
Baytur, YB | 1 |
Nagata, T | 1 |
Mizutani, N | 1 |
Sugimoto, Y | 4 |
Nakamura, S | 1 |
Zhong, C | 1 |
Kalogeromitros, D | 1 |
Katsarou, A | 1 |
Armenaka, M | 1 |
Rigopoulos, D | 1 |
Zapanti, M | 1 |
Stratigos, I | 1 |
Itoh, F | 1 |
Komatsu, Y | 1 |
Taya, F | 1 |
Isaji, M | 1 |
Kojima, M | 1 |
Momose, Y | 1 |
Suzawa, H | 1 |
Miyata, H | 1 |
Shibazaki, T | 1 |
Yanni, JM | 4 |
Stephens, DJ | 2 |
Parnell, DW | 1 |
Spellman, JM | 3 |
Fukagawa, K | 1 |
Saito, H | 1 |
Azuma, N | 1 |
Tsubota, K | 2 |
Iikura, Y | 1 |
Oguchi, Y | 1 |
Ciprandi, G | 1 |
Buscaglia, S | 1 |
Pesce, GP | 1 |
Bagnasco, M | 1 |
Canonica, GW | 1 |
Aichane, A | 1 |
Campbell, AM | 1 |
Chanal, I | 1 |
Richard, MC | 1 |
Arnaud, B | 1 |
Michel, FB | 1 |
Bousquet, J | 1 |
Fujishima, H | 2 |
Saito, I | 1 |
Takeuchi, T | 1 |
Shinozaki, N | 1 |
Miller, ST | 1 |
Weimer, LK | 2 |
Graff, G | 1 |
Parnell, D | 1 |
Lang, LS | 1 |
Brady, MT | 1 |
Gamache, DA | 2 |
Xu, SX | 2 |
Meijer, F | 1 |
Tak, C | 1 |
van Haeringen, NJ | 1 |
Kijlstra, A | 1 |
Leonardi, AA | 1 |
Smith, LM | 3 |
Fregona, IA | 3 |
George, MA | 2 |
Secchi, AG | 4 |
Yamaji, M | 1 |
Takada, M | 2 |
Fujiwara, R | 1 |
Ohishi, H | 1 |
Izushi, K | 4 |
Struck, HG | 1 |
Wicht, A | 1 |
Pönicke, K | 1 |
Lautenschläger, C | 1 |
Lübbe, D | 1 |
Radice, M | 1 |
Plebani, M | 2 |
Abatangelo, G | 1 |
Borghesan, F | 1 |
Faggian, D | 1 |
Depaoli, M | 1 |
Stokes, TC | 2 |
Feinberg, G | 2 |
Tiligada, E | 1 |
Aslanis, D | 1 |
Delitheos, A | 1 |
Varonos, D | 1 |
Yamada, T | 1 |
Nakahara, H | 2 |
Watanabe, T | 1 |
Anderson, DF | 2 |
Ahluwalia, P | 1 |
Wilson, SJ | 1 |
McGill, JI | 1 |
Church, MK | 1 |
Revel, L | 1 |
Colombo, S | 1 |
Ferrari, F | 1 |
Folco, G | 1 |
Rovati, LC | 1 |
Makovec, F | 1 |
Awouters, F | 1 |
Niemegeers, CJ | 1 |
Jansen, T | 1 |
Megens, AA | 1 |
Janssen, PA | 1 |
Berdy, GJ | 1 |
Giovanoni, RL | 1 |
Tasaka, K | 1 |
Schiavone, M | 1 |
Centofanti, M | 1 |
Allansmith, MR | 1 |
Bucci, MG | 1 |
Gismondi, M | 1 |
Daniotti, E | 1 |
Carniel, G | 1 |
Friedlaender, MH | 1 |
Dreborg, S | 1 |
Agrell, B | 1 |
Foucard, T | 1 |
Kjellman, NI | 1 |
Koivikko, A | 1 |
Nilsson, S | 1 |
Garceau, D | 1 |
Ford-Hutchinson, AW | 1 |
Sakuma, Y | 1 |
Mita, H | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
A Double-blind,Placebo-controlled, Randomized, Crossover Trial of Mint Tea High in Rosmarinic Acid in Adults With Nasal Polyposis[NCT00465543] | Phase 2 | 22 participants (Actual) | Interventional | 2007-05-31 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
12 reviews available for histamine and Allergic Conjunctivitis
Article | Year |
---|---|
PAF-induced inflammatory and immuno-allergic ophthalmic diseases and their mitigation with PAF receptor antagonists: Cell and nuclear effects.
Topics: Conjunctivitis, Allergic; Eye Diseases; Histamine; Humans; Inflammation; Platelet Activating Factor | 2022 |
Neuropathic pain and itch: mechanisms in allergic conjunctivitis.
Topics: Conjunctiva; Conjunctivitis, Allergic; Histamine; Humans; Inflammation; Neuralgia; Pruritus | 2022 |
Topical antihistamines and mast cell stabilisers for treating seasonal and perennial allergic conjunctivitis.
Topics: Anti-Allergic Agents; Conjunctivitis, Allergic; Histamine; Histamine Antagonists; Humans; Mast Cells | 2015 |
Multiple action agents and the eye: do they really stabilize mast cells?
Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acid; Conjunctivitis, Allergic; Cytokines; Dibenzazep | 2009 |
The role of histamine in ocular allergy.
Topics: Animals; Conjunctiva; Conjunctivitis, Allergic; Eye; Histamine; Histamine Antagonists; Humans; Hyper | 2010 |
Ophthalmic antihistamines and H1-H4 receptors.
Topics: Animals; Anti-Allergic Agents; Binding, Competitive; Conjunctivitis, Allergic; Histamine; Histamine | 2012 |
Antihistamines in rhinoconjunctivitis.
Topics: Animals; Conjunctivitis, Allergic; Histamine; Histamine H1 Antagonists; Humans; Receptors, Histamine | 2002 |
H1-antihistamines in the elderly.
Topics: Aged; Anaphylaxis; Conjunctivitis, Allergic; Histamine; Histamine H1 Antagonists; Humans; Hypersensi | 2002 |
Advances in H1-antihistamines.
Topics: Central Nervous System; Conjunctivitis, Allergic; Heart; Histamine; Histamine H1 Antagonists; Humans | 2004 |
[Oral second generation antihistamines in allergic rhinitis].
Topics: Administration, Oral; Adult; Anti-Allergic Agents; Cetirizine; Child; Conjunctivitis, Allergic; Cont | 2005 |
Role of histamine in allergic conjunctivitis.
Topics: Conjunctivitis, Allergic; Cytokines; Fibroblasts; Histamine; Histamine H1 Antagonists; Humans; Mast | 2000 |
Management of seasonal allergic conjunctivitis (SAC): current therapeutic strategies.
Topics: Administration, Topical; Anti-Inflammatory Agents; Conjunctivitis, Allergic; Forecasting; Histamine; | 2001 |
9 trials available for histamine and Allergic Conjunctivitis
Article | Year |
---|---|
Evaluating the efficacy of epinastine ophthalmic solution using a conjunctivitis allergen challenge model in patients with birch pollen allergic conjunctivitis.
Topics: Adult; Allergens; Anti-Allergic Agents; Betula; Biomarkers; Conjunctivitis, Allergic; Dibenzazepines | 2017 |
Nasal corticosteroid treatment reduces substance P levels in tear fluid in allergic rhinoconjunctivitis.
Topics: Administration, Intranasal; Adrenal Cortex Hormones; Adult; Androstadienes; Antigens, Plant; Conjunc | 2012 |
Double-masked, randomized, placebo-controlled clinical study of the mast cell-stabilizing effects of treatment with olopatadine in the conjunctival allergen challenge model in humans.
Topics: Administration, Topical; Adult; Allergens; Conjunctivitis, Allergic; Dibenzoxepins; Double-Blind Met | 2003 |
Extract of Perilla frutescens enriched for rosmarinic acid, a polyphenolic phytochemical, inhibits seasonal allergic rhinoconjunctivitis in humans.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Chemokine CCL11; Chemokines, CC; Cinnamates; Conjunc | 2004 |
Rapid onset of action of levocabastine eye-drops in histamine-induced conjunctivitis.
Topics: Adult; Animals; Chick Embryo; Conjunctivitis, Allergic; Double-Blind Method; Female; Histamine; Hist | 1993 |
Nedocromil sodium and levocabastine reduce the symptoms of conjunctival allergen challenge by different mechanisms.
Topics: Adult; Anti-Allergic Agents; Conjunctiva; Conjunctivitis, Allergic; E-Selectin; Female; Histamine; H | 2001 |
Allergic conjunctivitis: a survey of new antihistamines.
Topics: Animals; Conjunctiva; Conjunctivitis, Allergic; Dose-Response Relationship, Drug; Double-Blind Metho | 1991 |
Conjunctival hyperresponsiveness to ocular histamine challenge in patients with vernal conjunctivitis.
Topics: Adolescent; Adult; Child; Child, Preschool; Conjunctiva; Conjunctivitis, Allergic; Dose-Response Rel | 1992 |
A double-blind, multicenter immunotherapy trial in children, using a purified and standardized Cladosporium herbarum preparation. I. Clinical results.
Topics: Adolescent; Asthma; Bronchial Provocation Tests; Child; Child, Preschool; Cladosporium; Clinical Tri | 1986 |
59 other studies available for histamine and Allergic Conjunctivitis
Article | Year |
---|---|
Therapeutic efficacy of topical blockade of substance P in experimental allergic red eye.
Topics: Animals; Conjunctiva; Conjunctivitis, Allergic; Eosinophils; Guinea Pigs; Histamine; Substance P | 2022 |
Gp130 Promotes Inflammation via the STAT3/JAK2 Pathway in Allergic Conjunctivitis.
Topics: Animals; Conjunctivitis, Allergic; Cytokine Receptor gp130; Histamine; Inflammation; Janus Kinase 2; | 2023 |
Decreased viability and proliferation of CHANG conjunctival epithelial cells after contact with ultraviolet light-irradiated pollen.
Topics: Allergens; Alnus; Cell Line; Cell Proliferation; Cell Survival; Conjunctiva; Conjunctivitis, Allergi | 2018 |
Treatment with galectin-1 eye drops regulates mast cell degranulation and attenuates the severity of conjunctivitis.
Topics: Animals; Anti-Allergic Agents; Anti-Inflammatory Agents; Cell Degranulation; Cell Movement; Conjunct | 2018 |
Context-Dependent Regulation of Conjunctival Goblet Cell Function by Allergic Mediators.
Topics: Animals; Cell Proliferation; Conjunctiva; Conjunctival Diseases; Conjunctivitis, Allergic; Cytokines | 2018 |
In vitro and in vivo performance of epinastine hydrochloride-releasing contact lenses.
Topics: Animals; Conjunctivitis, Allergic; Contact Lenses, Hydrophilic; Delayed-Action Preparations; Dibenza | 2019 |
Resolvin D1 and aspirin-triggered resolvin D1 regulate histamine-stimulated conjunctival goblet cell secretion.
Topics: Animals; Aspirin; Bodily Secretions; Calcium Signaling; Cells, Cultured; Conjunctivitis, Allergic; D | 2013 |
Involvement of chymase in allergic conjunctivitis of guinea pigs.
Topics: Allergens; Animals; Chymases; Conjunctivitis, Allergic; Disease Models, Animal; Enzyme Inhibitors; G | 2013 |
Antiallergic effects of pigments isolated from green sea urchin (Strongylocentrotus droebachiensis) shells.
Topics: Animal Shells; Animals; Anti-Allergic Agents; Conjunctivitis, Allergic; Dibenzoxepins; Disease Model | 2013 |
Culture medium from TNF-α-stimulated mesenchymal stem cells attenuates allergic conjunctivitis through multiple antiallergic mechanisms.
Topics: Ambrosia; Animals; B-Lymphocytes; Bone Marrow Cells; Capillary Permeability; Cell Differentiation; C | 2015 |
A histamine-independent itch pathway is required for allergic ocular itch.
Topics: Animals; Biomarkers; Conjunctivitis, Allergic; Histamine; Mice; Mice, Knockout; Pruritus; Transient | 2016 |
[A preliminary study on the role of substance P in histamine-nasal-spray-induced allergic conjunctivitis in guinea pigs].
Topics: Animals; Conjunctiva; Conjunctivitis, Allergic; Eosinophils; Guinea Pigs; Histamine; Male; Mast Cell | 2015 |
Treatment with olopatadine and naphazoline hydrochloride reduces allergic conjunctivitis in mice through alterations in inflammation, NGF and VEGF.
Topics: Animals; Blotting, Western; Conjunctivitis, Allergic; Cytokines; Disease Models, Animal; Drug Therap | 2016 |
Biomimetic contact lenses eluting olopatadine for allergic conjunctivitis.
Topics: Amino Acids; Animals; Biomimetic Materials; Cell Line; Cell Survival; Chickens; Conjunctivitis, Alle | 2016 |
Role of histamine H(4) receptor in allergic conjunctivitis in mice.
Topics: Animals; Conjunctivitis, Allergic; Histamine; Histamine Agonists; Male; Mice; Mice, Inbred ICR; Mole | 2009 |
Bepotastine besilate, a highly selective histamine H(1) receptor antagonist, suppresses vascular hyperpermeability and eosinophil recruitment in in vitro and in vivo experimental allergic conjunctivitis models.
Topics: Animals; Capillary Permeability; Cells, Cultured; Chemotaxis, Leukocyte; Conjunctiva; Conjunctivitis | 2010 |
Relation between cooling sheet effect and tear histamine concenration in allergic conjunctivitis.
Topics: Conjunctivitis, Allergic; Cryotherapy; Enzyme-Linked Immunosorbent Assay; Histamine; Histamine H1 An | 2010 |
Evaluation of histamine-induced conjunctival oedema in guinea pigs by means of image analysis.
Topics: Animals; Coloring Agents; Conjunctiva; Conjunctivitis, Allergic; Evans Blue; Guinea Pigs; Histamine; | 2010 |
Effect of Perilla frutescens var. acuta Kudo and rosmarinic acid on allergic inflammatory reactions.
Topics: Animals; Blotting, Western; Cell Line; Cinnamates; Conjunctivitis, Allergic; Cyclooxygenase 2; Cytok | 2011 |
Pre-seasonal treatment with topical olopatadine suppresses the clinical symptoms of seasonal allergic conjunctivitis.
Topics: Administration, Topical; Adult; Conjunctivitis, Allergic; Dibenzoxepins; Female; Histamine; Histamin | 2011 |
Ameliorative effect of thymoquinone on ovalbumin-induced allergic conjunctivitis in Balb/c mice.
Topics: Animals; Benzoquinones; Chromatography, High Pressure Liquid; Conjunctivitis, Allergic; Cytokines; D | 2011 |
[Allergic mediators in tear from children with seasonal and perennial allergic conjunctivitis].
Topics: Adolescent; Biomarkers; Child; Child, Preschool; Chitinases; Conjunctivitis, Allergic; E-Selectin; E | 2011 |
Role of histamine and its receptor subtypes in stimulation of conjunctival goblet cell secretion.
Topics: Animals; Blotting, Western; Cells, Cultured; Cimetidine; Conjunctiva; Conjunctivitis, Allergic; Dose | 2012 |
Involvement of leukotriene B4 in itching in a mouse model of ocular allergy.
Topics: Allergens; Ambrosia; Animals; Conjunctivitis, Allergic; Disease Models, Animal; Glucocorticoids; His | 2012 |
Effects of nonsteroidal anti-inflammatory drugs on experimental allergic conjunctivitis in Guinea pigs.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antigens; Benzophenones; | 2003 |
[The role of histamine in the etiology of allergic conjunctivitis].
Topics: Anti-Allergic Agents; Conjunctivitis; Conjunctivitis, Allergic; Histamine; Histamine Agents; Histami | 1951 |
A chronic model for evaluating the itching associated with allergic conjunctivitis in rats.
Topics: Animals; Anti-Allergic Agents; Antigens; Chronic Disease; Conjunctivitis, Allergic; Disease Models, | 2004 |
Is the menstrual cycle affecting the skin prick test reactivity?
Topics: Adult; Allergens; Conjunctivitis, Allergic; Estradiol; Female; Follicle Stimulating Hormone; Histami | 2004 |
Effects of multiple dexamethasone treatments on aggravation of allergic conjunctivitis associated with mast cell hyperplasia.
Topics: Allergens; Animals; Antigens, Plant; Cell Count; Conjunctivitis, Allergic; Cryptomeria; Dexamethason | 2008 |
Effect of (Z)-11-[3-(dimethylamino) propylidene]-6,11-dihydrodibenz[b,e]oxepin-2-acetic acid hydrochloride on experimental allergic conjunctivitis and rhinitis in rats and guinea pigs.
Topics: Administration, Oral; Administration, Topical; Allergens; Animals; Anti-Allergic Agents; Ascaris; Co | 1995 |
Influence of the menstrual cycle on skin-prick test reactions to histamine, morphine and allergen.
Topics: Adult; Allergens; Asthma; Conjunctivitis, Allergic; Drug Hypersensitivity; Estrogens; Female; Histam | 1995 |
[Effect of tranilast ophthalmic solution on allergic conjunctivitis in guinea pigs].
Topics: Animals; Conjunctiva; Conjunctivitis, Allergic; Cromolyn Sodium; Diphenhydramine; Fluorescein; Fluor | 1993 |
Preclinical efficacy of emedastine, a potent, selective histamine H1 antagonist for topical ocular use.
Topics: Administration, Topical; Anaphylaxis; Animals; Benzimidazoles; Capillary Permeability; Conjunctiva; | 1994 |
Histamine and tryptase levels in allergic conjunctivitis and vernal keratoconjunctivitis.
Topics: Child; Chymases; Conjunctiva; Conjunctivitis, Allergic; Epithelium; Female; Histamine; Humans; Male; | 1994 |
Ocular challenge and hyperresponsiveness to histamine in patients with allergic conjunctivitis.
Topics: Adolescent; Adult; Allergens; Cell Adhesion Molecules; Conjunctivitis, Allergic; Eye; Female; Histam | 1993 |
Precision of conjunctival provocation tests in right and left eyes.
Topics: Adult; Allergens; Conjunctiva; Conjunctivitis, Allergic; Dose-Response Relationship, Immunologic; Hi | 1993 |
Measurement of interleukin-4 and histamine in superficial cells of conjunctiva in patients with allergic conjunctivitis.
Topics: Adolescent; Adult; Aged; Allergens; Child; Conjunctiva; Conjunctivitis; Conjunctivitis, Allergic; En | 1996 |
The in vitro and in vivo ocular pharmacology of olopatadine (AL-4943A), an effective anti-allergic/antihistaminic agent.
Topics: Administration, Topical; Anaphylaxis; Animals; Anti-Allergic Agents; Capillary Permeability; Conjunc | 1996 |
Olopatadine (AL-4943A): ligand binding and functional studies on a novel, long acting H1-selective histamine antagonist and anti-allergic agent for use in allergic conjunctivitis.
Topics: Anti-Allergic Agents; Binding, Competitive; Cell Line; Cells, Cultured; Conjunctiva; Conjunctivitis, | 1996 |
Interaction between nitric oxide and prostaglandin synthesis in the acute phase of allergic conjunctivitis.
Topics: Administration, Topical; Albumins; Animals; Antigens; Capillary Permeability; Conjunctival Diseases; | 1996 |
Histaminase activity in patients with vernal keratoconjunctivitis.
Topics: Adolescent; Adult; Amine Oxidase (Copper-Containing); Child; Child, Preschool; Conjunctivitis, Aller | 1995 |
Role of substance P in experimental allergic conjunctivitis in guinea pigs.
Topics: Animals; Capillary Permeability; Capsaicin; Conjunctiva; Conjunctivitis, Allergic; Dipeptides; Disea | 1997 |
[Histamine in tears in allergic rhinoconjunctivitis].
Topics: Adolescent; Adult; Conjunctivitis, Allergic; Desensitization, Immunologic; Female; Histamine; Humans | 1998 |
Inhibition of histamine-induced human conjunctival epithelial cell responses by ocular allergy drugs.
Topics: Cells, Cultured; Chromatography, Ion Exchange; Conjunctiva; Conjunctivitis, Allergic; Dose-Response | 1999 |
Histamine effects on conjunctival fibroblasts from patients with vernal conjunctivitis.
Topics: Cell Culture Techniques; Cell Division; Conjunctiva; Conjunctivitis, Allergic; Dose-Response Relatio | 1999 |
Tear and serum soluble leukocyte activation markers in conjunctival allergic diseases.
Topics: Adolescent; Adult; Biomarkers; Blood Proteins; Conjunctivitis, Allergic; Conjunctivitis, Bacterial; | 2000 |
Changes in histamine content following pharmacologically-induced mast cell degranulation in the rat conjunctiva.
Topics: Animals; Cell Degranulation; Conjunctiva; Conjunctivitis, Allergic; Cromolyn Sodium; Disease Models, | 2000 |
Experimental allergic conjunctivitis in guinea pigs induced by Japanese cedar pollen.
Topics: Animals; Anti-Allergic Agents; Capillary Permeability; Conjunctivitis, Allergic; Disease Models, Ani | 2000 |
Vascular permeability in allergic conjunctivitis in mice lacking histamine H1 receptors.
Topics: Animals; Capillary Permeability; Conjunctivitis, Allergic; Free Radical Scavengers; Histamine; Hista | 2000 |
Respiratory syncytial virus may be a pathogen in allergic conjunctivitis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Conjunctivitis, Allergic; Enzym | 2002 |
CR 2039, a new bis-(1H-tetrazol-5-yl)phenylbenzamide derivative with potential for the topical treatment of asthma.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Administration, Inhalation; Anaphylaxis; Animals; Asthma; Benza | 1992 |
Levocabastine: pharmacological profile of a highly effective inhibitor of allergic reactions.
Topics: Anaphylaxis; Animals; Ascaris; Conjunctivitis, Allergic; Dogs; Guinea Pigs; Histamine; Histamine H1 | 1992 |
Inhibitory effect of levocabastine on experimental allergic conjunctivitis in guinea pigs.
Topics: Aminopyridines; Animals; Antigens; Capillary Permeability; Conjunctivitis, Allergic; Cromolyn Sodium | 1991 |
Correlation between conjunctival provocation test (CPT) and systemic allergometric tests in allergic conjunctivitis.
Topics: Adolescent; Adult; Allergens; Child; Conjunctiva; Conjunctivitis, Allergic; Female; Histamine; Human | 1990 |
Conjunctival provocative tests: a model of human ocular allergy.
Topics: Adolescent; Adult; Allergens; Body Temperature; Conjunctivitis, Allergic; Female; Histamine; Humans; | 1989 |
Application of histamine-induced conjunctivitis to the assessment of a topical antihistamine, levocabastine.
Topics: Administration, Topical; Animals; Conjunctivitis, Allergic; Drug Evaluation, Preclinical; Guinea Pig | 1987 |
Levocabastine. Evaluation in the histamine and compound 48/80 models of ocular allergy in humans.
Topics: Conjunctivitis, Allergic; Histamine; Humans; p-Methoxy-N-methylphenethylamine; Piperidines | 1988 |
The role of leukotriene D4 as a mediator of allergic conjunctivitis in the guinea-pig.
Topics: Animals; Capillary Permeability; Conjunctivitis, Allergic; Guinea Pigs; Histamine; Indomethacin; Ket | 1987 |
[Lacrimal level of histamine in allergic conjunctival diseases].
Topics: Conjunctivitis, Allergic; Histamine; Humans; Tears | 1986 |