Page last updated: 2024-10-18

histamine and Allergic Conjunctivitis

histamine has been researched along with Allergic Conjunctivitis in 80 studies

Research Excerpts

ExcerptRelevanceReference
"The objective of this review was to assess the effects of topical antihistamines and mast cell stabilisers, alone or in combination, for use in treating seasonal and perennial allergic conjunctivitis."8.91Topical antihistamines and mast cell stabilisers for treating seasonal and perennial allergic conjunctivitis. ( Azuara-Blanco, A; Castillo, M; Mustafa, MS; Mustafa, MZ; Scott, NW, 2015)
"The aim of the current study was to investigate whether olopatadine and naphazoline hydrochloride reduce allergic conjunctivitis in mice through alterations in inflammation, NGF and VEGF."7.83Treatment with olopatadine and naphazoline hydrochloride reduces allergic conjunctivitis in mice through alterations in inflammation, NGF and VEGF. ( He, H; Quan, L, 2016)
" The aim of this study was to evaluate the effects of TQ on ovalbumin (OVA)-induced allergic conjunctivitis (AC) in Balb/c."7.77Ameliorative effect of thymoquinone on ovalbumin-induced allergic conjunctivitis in Balb/c mice. ( Asim, MB; Hayat, K; Li, M; Nawaz, M; Sun, N; Zhang, L, 2011)
"To elucidate the ocular pharmacological properties of bepotastine besilate, a selective histamine H(1) receptor antagonist, when compared with other histamine H(1) receptor antagonists, using guinea pig allergic conjunctivitis models and in vitro models of eosinophil recruitment and mast cell membrane stabilization."7.76Bepotastine besilate, a highly selective histamine H(1) receptor antagonist, suppresses vascular hyperpermeability and eosinophil recruitment in in vitro and in vivo experimental allergic conjunctivitis models. ( Atsumi, I; Fujii, A; Iemura, M; Kida, T; Sakai, O; Sakaki, H; Wada, T, 2010)
"Six allergic conjunctivitis patients (12 eyes) and 4 healthy volunteers (8 eyes) were investigated in terms of the effect of cooling sheets on eye itching and tear histamine concentration, before and 5 min after cooling the eyelids with cooling sheets."7.76Relation between cooling sheet effect and tear histamine concenration in allergic conjunctivitis. ( Hirakawa, N; Yano, H; Yanoshita, R; Yoshii, M, 2010)
"We investigated the character of histamine H(1) receptor and H(4) receptor in allergic conjunctivitis."7.75Role of histamine H(4) receptor in allergic conjunctivitis in mice. ( Kagawa, Y; Kamei, C; Kurata, Y; Nakano, Y; Ono, R; Takahashi, Y, 2009)
"To clarify the role of histamine H1 receptors in allergic conjunctivitis, changes in vascular permeability of the conjunctiva were measured in histamine H1 receptor deficient mice."7.70Vascular permeability in allergic conjunctivitis in mice lacking histamine H1 receptors. ( Izushi, K; Kamei, C; Nakahara, H; Sugimoto, Y; Watanabe, T, 2000)
"The role of substance P in experimental allergic conjunctivitis induced by egg albumin was investigated with guinea pigs."7.69Role of substance P in experimental allergic conjunctivitis in guinea pigs. ( Fujiwara, R; Izushi, K; Kamei, C; Ohishi, H; Sugimoto, Y; Takada, M; Yamaji, M, 1997)
" At the same dose histamine skin reactions and at slightly higher doses passive cutaneous anaphylactic reactions are inhibited."7.68Levocabastine: pharmacological profile of a highly effective inhibitor of allergic reactions. ( Awouters, F; Jansen, T; Janssen, PA; Megens, AA; Niemegeers, CJ, 1992)
"The effect of the ophthalmic solution of tranilast, an anti-allergic agent, on allergic conjunctivitis was studied in passively sensitized guinea pigs."7.68[Effect of tranilast ophthalmic solution on allergic conjunctivitis in guinea pigs]. ( Isaji, M; Itoh, F; Kojima, M; Komatsu, Y; Miyata, H; Momose, Y; Shibazaki, T; Suzawa, H; Taya, F, 1993)
" Dose-response curves demonstrated that 0."6.67Allergic conjunctivitis: a survey of new antihistamines. ( Abelson, MB; Berdy, GJ; George, MA; Giovanoni, RL; Smith, LM, 1991)
"The effects of histamine in allergic conjunctivitis are mediated by H1-receptor activation on blood vessels and nociceptive nerves."6.41Role of histamine in allergic conjunctivitis. ( Leonardi, A, 2000)
"Ten patients with cedar pollen-allergic conjunctivitis and 10 patients with postsurgical conjunctivitis were enrolled in this study."5.29Measurement of interleukin-4 and histamine in superficial cells of conjunctiva in patients with allergic conjunctivitis. ( Fujishima, H; Saito, I; Shinozaki, N; Takeuchi, T; Tsubota, K, 1996)
"The objective of this review was to assess the effects of topical antihistamines and mast cell stabilisers, alone or in combination, for use in treating seasonal and perennial allergic conjunctivitis."4.91Topical antihistamines and mast cell stabilisers for treating seasonal and perennial allergic conjunctivitis. ( Azuara-Blanco, A; Castillo, M; Mustafa, MS; Mustafa, MZ; Scott, NW, 2015)
"In the elderly, H1-antihistamine therapy is commonly prescribed for treatment of rhinitis, conjunctivitis, pruritus, eczema, urticaria, and for prophylaxis of anaphylactoid reactions."4.81H1-antihistamines in the elderly. ( Kaliner, MA, 2002)
" In this study, we developed epinastine hydrochloride-releasing daily soft contact lenses for treatment of allergic conjunctivitis and examined their in vitro and in vivo performance."3.91In vitro and in vivo performance of epinastine hydrochloride-releasing contact lenses. ( Arai, R; Fukushima, A; Hino, S; Ishida, W; Kishimoto, T; Matsunaga, T; Minami, T; Nakajima, I; Yamagami, S, 2019)
"The aim of the current study was to investigate whether olopatadine and naphazoline hydrochloride reduce allergic conjunctivitis in mice through alterations in inflammation, NGF and VEGF."3.83Treatment with olopatadine and naphazoline hydrochloride reduces allergic conjunctivitis in mice through alterations in inflammation, NGF and VEGF. ( He, H; Quan, L, 2016)
" They were able to inhibit the release of histamine and TNF-α from sensitized mast cells, proving their potential application in preventing and treating allergic conjunctivitis."3.83Biomimetic contact lenses eluting olopatadine for allergic conjunctivitis. ( Alvarez-Lorenzo, C; Concheiro, A; González-Chomón, C; Silva, M, 2016)
" As resolvin (Rv) D1 is produced in the cornea, pro-resolution mediators could be effective in regulating inflammatory responses to histamine in allergic conjunctivitis."3.79Resolvin D1 and aspirin-triggered resolvin D1 regulate histamine-stimulated conjunctival goblet cell secretion. ( Carozza, RB; Chiang, N; Dartt, DA; Hodges, RR; Jiao, J; Li, D; Serhan, CN; Shatos, MA, 2013)
" The aim of this study was to evaluate the effects of TQ on ovalbumin (OVA)-induced allergic conjunctivitis (AC) in Balb/c."3.77Ameliorative effect of thymoquinone on ovalbumin-induced allergic conjunctivitis in Balb/c mice. ( Asim, MB; Hayat, K; Li, M; Nawaz, M; Sun, N; Zhang, L, 2011)
"Conjunctival oedema is commonly observed in patients with allergic conjunctivitis and can be induced by histamine."3.76Evaluation of histamine-induced conjunctival oedema in guinea pigs by means of image analysis. ( Fukushima, A; Kayasuga, A; Mibu, H; Shii, D; Sumi, T; Tada, K; Takahashi, A, 2010)
"Six allergic conjunctivitis patients (12 eyes) and 4 healthy volunteers (8 eyes) were investigated in terms of the effect of cooling sheets on eye itching and tear histamine concentration, before and 5 min after cooling the eyelids with cooling sheets."3.76Relation between cooling sheet effect and tear histamine concenration in allergic conjunctivitis. ( Hirakawa, N; Yano, H; Yanoshita, R; Yoshii, M, 2010)
"To elucidate the ocular pharmacological properties of bepotastine besilate, a selective histamine H(1) receptor antagonist, when compared with other histamine H(1) receptor antagonists, using guinea pig allergic conjunctivitis models and in vitro models of eosinophil recruitment and mast cell membrane stabilization."3.76Bepotastine besilate, a highly selective histamine H(1) receptor antagonist, suppresses vascular hyperpermeability and eosinophil recruitment in in vitro and in vivo experimental allergic conjunctivitis models. ( Atsumi, I; Fujii, A; Iemura, M; Kida, T; Sakai, O; Sakaki, H; Wada, T, 2010)
"We investigated the character of histamine H(1) receptor and H(4) receptor in allergic conjunctivitis."3.75Role of histamine H(4) receptor in allergic conjunctivitis in mice. ( Kagawa, Y; Kamei, C; Kurata, Y; Nakano, Y; Ono, R; Takahashi, Y, 2009)
" The levels of IL-4 and histamine in the specimens and mean IL-4 tear level were significantly increased in patients with allergic conjunctivitis."3.71Respiratory syncytial virus may be a pathogen in allergic conjunctivitis. ( Fujishima, H, 2002)
"To clarify the role of histamine H1 receptors in allergic conjunctivitis, changes in vascular permeability of the conjunctiva were measured in histamine H1 receptor deficient mice."3.70Vascular permeability in allergic conjunctivitis in mice lacking histamine H1 receptors. ( Izushi, K; Kamei, C; Nakahara, H; Sugimoto, Y; Watanabe, T, 2000)
"The classic clinical symptoms of allergic conjunctivitis (type I allergy)--itching and lacrimation--are the effect of histamine."3.70[Histamine in tears in allergic rhinoconjunctivitis]. ( Lautenschläger, C; Lübbe, D; Pönicke, K; Struck, HG; Wicht, A, 1998)
"The role of substance P in experimental allergic conjunctivitis induced by egg albumin was investigated with guinea pigs."3.69Role of substance P in experimental allergic conjunctivitis in guinea pigs. ( Fujiwara, R; Izushi, K; Kamei, C; Ohishi, H; Sugimoto, Y; Takada, M; Yamaji, M, 1997)
"The effect of the ophthalmic solution of tranilast, an anti-allergic agent, on allergic conjunctivitis was studied in passively sensitized guinea pigs."3.68[Effect of tranilast ophthalmic solution on allergic conjunctivitis in guinea pigs]. ( Isaji, M; Itoh, F; Kojima, M; Komatsu, Y; Miyata, H; Momose, Y; Shibazaki, T; Suzawa, H; Taya, F, 1993)
" At the same dose histamine skin reactions and at slightly higher doses passive cutaneous anaphylactic reactions are inhibited."3.68Levocabastine: pharmacological profile of a highly effective inhibitor of allergic reactions. ( Awouters, F; Jansen, T; Janssen, PA; Megens, AA; Niemegeers, CJ, 1992)
"Allergic conjunctivitis is highly prevalent and affects up to one third of the general population."2.82Neuropathic pain and itch: mechanisms in allergic conjunctivitis. ( Chisolm, S; Kalangara, JP; Kuruvilla, ME; Vanijcharoenkarn, K, 2022)
"Tear histamine levels were significantly lower after challenge in the eyes pretreated with olopatadine compared with placebo (mean [SD], 7 [8] vs 22 [12] nmol/L; P = 0."2.71Double-masked, randomized, placebo-controlled clinical study of the mast cell-stabilizing effects of treatment with olopatadine in the conjunctival allergen challenge model in humans. ( Abelson, MB; Leonardi, A, 2003)
"Nedocromil sodium treatment reduced tear concentrations of histamine (by 77%) and PGD(2) (by 70%) at 30 minutes after challenge (both P <."2.70Nedocromil sodium and levocabastine reduce the symptoms of conjunctival allergen challenge by different mechanisms. ( Ahluwalia, P; Anderson, DF; Church, MK; McGill, JI; Wilson, SJ, 2001)
"Levocabastine eye-drops were well-tolerated and no adverse reactions to the study drug were reported."2.67Rapid onset of action of levocabastine eye-drops in histamine-induced conjunctivitis. ( Feinberg, G; Stokes, TC, 1993)
" Dose-response curves demonstrated that 0."2.67Allergic conjunctivitis: a survey of new antihistamines. ( Abelson, MB; Berdy, GJ; George, MA; Giovanoni, RL; Smith, LM, 1991)
" Moreover, the threshold concentration of histamine diphosphate, extrapolated from each individual dose-response curve, was significantly (p less than 0."2.67Conjunctival hyperresponsiveness to ocular histamine challenge in patients with vernal conjunctivitis. ( Allansmith, MR; Bonini, S; Bucci, MG; Centofanti, M; Schiavone, M, 1992)
"Ocular allergy is a disorder affecting increasing numbers of individuals worldwide."2.46The role of histamine in ocular allergy. ( Fukuda, K; Manzouri, B; Morohoshi, K; Ohbayashi, M; Ono, SJ, 2010)
"Histamine is a key mediator of the allergic immediate reaction."2.43[Oral second generation antihistamines in allergic rhinitis]. ( Riechelmann, H, 2005)
"The effects of histamine in allergic conjunctivitis are mediated by H1-receptor activation on blood vessels and nociceptive nerves."2.41Role of histamine in allergic conjunctivitis. ( Leonardi, A, 2000)
"Allergic conjunctivitis is the most common cause leading to ocular redness (OR)."1.72Therapeutic efficacy of topical blockade of substance P in experimental allergic red eye. ( Blanco, T; Chen, Y; Dana, R; Ge, H; Liu, L; Pang, K; Wang, S; Xia, Y, 2022)
"Twenty children with allergic conjunctivitis (17 SAC, and 3 PAC) and sixteen healthy children were included in this study."1.37[Allergic mediators in tear from children with seasonal and perennial allergic conjunctivitis]. ( Acera, A; González, N; Martínez, R; Soria, J; Suárez, T, 2011)
"After the onset of allergic conjunctivitis, both eyes were treated with topical olopatadine."1.37Pre-seasonal treatment with topical olopatadine suppresses the clinical symptoms of seasonal allergic conjunctivitis. ( Miyazawa, A; Nakazawa, T; Otani, T; Shimura, M; Yasuda, K, 2011)
"The histamine level was also reduced by EPPF or RA administration in the serum of OVA-sensitized mice."1.37Effect of Perilla frutescens var. acuta Kudo and rosmarinic acid on allergic inflammatory reactions. ( Ahn, HJ; Kim, HM; Oh, HA; Park, CS; Park, YS, 2011)
"In a Japanese cedar pollen-induced allergic conjunctivitis model in guinea pigs, symptoms were aggravated by repeated pollen challenges."1.35Effects of multiple dexamethasone treatments on aggravation of allergic conjunctivitis associated with mast cell hyperplasia. ( Fujii, M; Kohno, S; Mizutani, N; Nabe, T; Nagata, T, 2008)
"We report a new experimental allergic conjunctivitis with Japanese cedar pollen as antigen in guinea pigs, and the immunological characteristics of this model were also elucidated."1.31Experimental allergic conjunctivitis in guinea pigs induced by Japanese cedar pollen. ( Izushi, K; Kamei, C; Nakahara, H; Sugimoto, Y; Takada, M; Yamada, T, 2000)
"Tear histamine was measured in 10 allergic patients after allergen challenge."1.31Tear and serum soluble leukocyte activation markers in conjunctival allergic diseases. ( Borghesan, F; Depaoli, M; Faggian, D; Leonardi, A; Plebani, M; Secchi, AG, 2000)
" Comparisons of relative potency 30 min post dosing between emedastine and other anti-histamines demonstrated that emedastine is equipotent to ketotifen, and 7, 7, 10, 10, 100, 357, 3333, and 5813 times more potent than brompheniramine, chlorpheniramine, clemastine, pyrilamine, levocabastine, pheniramine, diphenhydramine, and antazoline, respectively."1.29Preclinical efficacy of emedastine, a potent, selective histamine H1 antagonist for topical ocular use. ( Parnell, DW; Spellman, JM; Stephens, DJ; Yanni, JM, 1994)
"Ten patients with cedar pollen-allergic conjunctivitis and 10 patients with postsurgical conjunctivitis were enrolled in this study."1.29Measurement of interleukin-4 and histamine in superficial cells of conjunctiva in patients with allergic conjunctivitis. ( Fujishima, H; Saito, I; Shinozaki, N; Takeuchi, T; Tsubota, K, 1996)
"Histamine release was not stimulated by AL-4943A at concentrations as high as 10 mM."1.29The in vitro and in vivo ocular pharmacology of olopatadine (AL-4943A), an effective anti-allergic/antihistaminic agent. ( Brady, MT; Gamache, DA; Graff, G; Lang, LS; Miller, ST; Parnell, D; Spellman, JM; Stephens, DJ; Weimer, LK; Yanni, JM, 1996)
"Histamine was measured by enzyme-linked immunosorbent assay in acid samples treated with perchloric to deactivate histaminase and in untreated samples."1.29Histaminase activity in patients with vernal keratoconjunctivitis. ( Abelson, MB; Fregona, IA; George, MA; Leonardi, AA; Secchi, AG; Smith, LM, 1995)
"Levocabastine is a potent competitor against histamine for conjunctival H1 receptors and should prove a useful, possibly long-acting drug for the reversal of inflammatory conjunctivitis and inhibition of its recurrence."1.27Application of histamine-induced conjunctivitis to the assessment of a topical antihistamine, levocabastine. ( Feinberg, G; Stokes, TC, 1987)
"Levocabastine (0."1.27Levocabastine. Evaluation in the histamine and compound 48/80 models of ocular allergy in humans. ( Abelson, MB; Smith, LM, 1988)
"Indomethacin failed to inhibit either challenge."1.27The role of leukotriene D4 as a mediator of allergic conjunctivitis in the guinea-pig. ( Ford-Hutchinson, AW; Garceau, D, 1987)

Research

Studies (80)

TimeframeStudies, this research(%)All Research%
pre-19907 (8.75)18.7374
1990's23 (28.75)18.2507
2000's20 (25.00)29.6817
2010's26 (32.50)24.3611
2020's4 (5.00)2.80

Authors

AuthorsStudies
Sharif, NA3
Kalangara, JP1
Vanijcharoenkarn, K1
Chisolm, S1
Kuruvilla, ME1
Wang, S1
Liu, L1
Blanco, T1
Ge, H1
Xia, Y1
Pang, K1
Chen, Y1
Dana, R1
Bao, J1
Zhang, P1
Wu, B1
Wang, J1
Li, S1
Li, A1
Jie, Y1
Heidinger, A1
Rabensteiner, DF1
Rabensteiner, J1
Kieslinger, P1
Horwath-Winter, J1
Stabentheiner, E1
Riedl, R1
Wedrich, A1
Schmut, O1
Mello-Bosnic, C1
Gimenes, AD1
Oliani, SM1
Gil, CD1
García-Posadas, L1
Hodges, RR3
Diebold, Y1
Dartt, DA3
Minami, T1
Ishida, W1
Kishimoto, T1
Nakajima, I1
Hino, S1
Arai, R1
Matsunaga, T1
Fukushima, A2
Yamagami, S1
Li, D2
Jiao, J1
Carozza, RB1
Shatos, MA1
Chiang, N1
Serhan, CN1
Nabe, T2
Kijitani, Y1
Kitagawa, Y1
Sakano, E1
Ueno, T1
Fujii, M2
Nakao, S1
Sakai, M1
Takai, S1
Pozharitskaya, ON1
Shikov, AN1
Makarova, MN1
Ivanova, SA1
Kosman, VM1
Makarov, VG1
Bazgier, V1
Berka, K1
Otyepka, M1
Ulrichová, J1
Su, W1
Wan, Q1
Huang, J1
Han, L1
Chen, X1
Chen, G1
Olsen, N1
Zheng, SG1
Liang, D1
Castillo, M1
Scott, NW1
Mustafa, MZ1
Mustafa, MS1
Azuara-Blanco, A1
Huang, CC1
Kim, YS1
Olson, WP1
Li, F1
Guo, C1
Luo, W1
Huang, AJW1
Liu, Q1
Li, T1
Zhao, C1
Quan, L1
He, H1
González-Chomón, C1
Silva, M1
Concheiro, A1
Alvarez-Lorenzo, C1
Tagawa, Y1
Namba, K1
Nakazono, Y1
Iwata, D1
Ishida, S1
Nakano, Y1
Takahashi, Y1
Ono, R1
Kurata, Y1
Kagawa, Y1
Kamei, C7
Lambiase, A1
Micera, A1
Bonini, S3
Kida, T1
Fujii, A1
Sakai, O1
Iemura, M1
Atsumi, I1
Wada, T1
Sakaki, H1
Hirakawa, N1
Yanoshita, R1
Yoshii, M1
Yano, H1
Takahashi, A1
Sumi, T1
Tada, K1
Mibu, H1
Shii, D1
Kayasuga, A1
Oh, HA1
Park, CS1
Ahn, HJ1
Park, YS1
Kim, HM1
Shimura, M1
Yasuda, K1
Miyazawa, A1
Otani, T1
Nakazawa, T1
Hayat, K1
Asim, MB1
Nawaz, M1
Li, M1
Zhang, L1
Sun, N1
Ohbayashi, M1
Manzouri, B1
Morohoshi, K1
Fukuda, K1
Ono, SJ1
Martínez, R1
Acera, A1
Soria, J1
González, N1
Suárez, T1
Hayashi, D1
Hayashi, C1
Shatos, M1
Andoh, T1
Sakai, K1
Urashima, M1
Kitazawa, K1
Honma, A1
Kuraishi, Y1
Callebaut, I1
Vandewalle, E1
Hox, V1
Bobic, S1
Jorissen, M1
Stalmans, I1
De Vries, A1
Scadding, G1
Hellings, PW1
Wade, L1
Bielory, L1
Rudner, S1
Howarth, P1
Kaliner, MA1
Leonardi, A5
Abelson, MB4
Hashimoto, T1
Igarashi, A1
Hoshina, F1
Yamada, M1
Toyoda, Y1
Notsu, Y1
Kohno, S2
LINNEN, HJ1
Minami, K1
Takano, H1
Osakabe, N1
Sanbongi, C1
Yanagisawa, R1
Inoue, K1
Yasuda, A1
Natsume, M1
Baba, S1
Ichiishi, E1
Yoshikawa, T1
Simons, FE1
Riechelmann, H1
Kirmaz, C1
Yuksel, H1
Mete, N1
Bayrak, P1
Baytur, YB1
Nagata, T1
Mizutani, N1
Sugimoto, Y4
Nakamura, S1
Zhong, C1
Kalogeromitros, D1
Katsarou, A1
Armenaka, M1
Rigopoulos, D1
Zapanti, M1
Stratigos, I1
Itoh, F1
Komatsu, Y1
Taya, F1
Isaji, M1
Kojima, M1
Momose, Y1
Suzawa, H1
Miyata, H1
Shibazaki, T1
Yanni, JM4
Stephens, DJ2
Parnell, DW1
Spellman, JM3
Fukagawa, K1
Saito, H1
Azuma, N1
Tsubota, K2
Iikura, Y1
Oguchi, Y1
Ciprandi, G1
Buscaglia, S1
Pesce, GP1
Bagnasco, M1
Canonica, GW1
Aichane, A1
Campbell, AM1
Chanal, I1
Richard, MC1
Arnaud, B1
Michel, FB1
Bousquet, J1
Fujishima, H2
Saito, I1
Takeuchi, T1
Shinozaki, N1
Miller, ST1
Weimer, LK2
Graff, G1
Parnell, D1
Lang, LS1
Brady, MT1
Gamache, DA2
Xu, SX2
Meijer, F1
Tak, C1
van Haeringen, NJ1
Kijlstra, A1
Leonardi, AA1
Smith, LM3
Fregona, IA3
George, MA2
Secchi, AG4
Yamaji, M1
Takada, M2
Fujiwara, R1
Ohishi, H1
Izushi, K4
Struck, HG1
Wicht, A1
Pönicke, K1
Lautenschläger, C1
Lübbe, D1
Radice, M1
Plebani, M2
Abatangelo, G1
Borghesan, F1
Faggian, D1
Depaoli, M1
Stokes, TC2
Feinberg, G2
Tiligada, E1
Aslanis, D1
Delitheos, A1
Varonos, D1
Yamada, T1
Nakahara, H2
Watanabe, T1
Anderson, DF2
Ahluwalia, P1
Wilson, SJ1
McGill, JI1
Church, MK1
Revel, L1
Colombo, S1
Ferrari, F1
Folco, G1
Rovati, LC1
Makovec, F1
Awouters, F1
Niemegeers, CJ1
Jansen, T1
Megens, AA1
Janssen, PA1
Berdy, GJ1
Giovanoni, RL1
Tasaka, K1
Schiavone, M1
Centofanti, M1
Allansmith, MR1
Bucci, MG1
Gismondi, M1
Daniotti, E1
Carniel, G1
Friedlaender, MH1
Dreborg, S1
Agrell, B1
Foucard, T1
Kjellman, NI1
Koivikko, A1
Nilsson, S1
Garceau, D1
Ford-Hutchinson, AW1
Sakuma, Y1
Mita, H1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Double-blind,Placebo-controlled, Randomized, Crossover Trial of Mint Tea High in Rosmarinic Acid in Adults With Nasal Polyposis[NCT00465543]Phase 222 participants (Actual)Interventional2007-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

12 reviews available for histamine and Allergic Conjunctivitis

ArticleYear
PAF-induced inflammatory and immuno-allergic ophthalmic diseases and their mitigation with PAF receptor antagonists: Cell and nuclear effects.
    BioFactors (Oxford, England), 2022, Volume: 48, Issue:6

    Topics: Conjunctivitis, Allergic; Eye Diseases; Histamine; Humans; Inflammation; Platelet Activating Factor

2022
Neuropathic pain and itch: mechanisms in allergic conjunctivitis.
    Current opinion in allergy and clinical immunology, 2022, 10-01, Volume: 22, Issue:5

    Topics: Conjunctiva; Conjunctivitis, Allergic; Histamine; Humans; Inflammation; Neuralgia; Pruritus

2022
Topical antihistamines and mast cell stabilisers for treating seasonal and perennial allergic conjunctivitis.
    The Cochrane database of systematic reviews, 2015, Jun-01, Issue:6

    Topics: Anti-Allergic Agents; Conjunctivitis, Allergic; Histamine; Histamine Antagonists; Humans; Mast Cells

2015
Multiple action agents and the eye: do they really stabilize mast cells?
    Current opinion in allergy and clinical immunology, 2009, Volume: 9, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acid; Conjunctivitis, Allergic; Cytokines; Dibenzazep

2009
The role of histamine in ocular allergy.
    Advances in experimental medicine and biology, 2010, Volume: 709

    Topics: Animals; Conjunctiva; Conjunctivitis, Allergic; Eye; Histamine; Histamine Antagonists; Humans; Hyper

2010
Ophthalmic antihistamines and H1-H4 receptors.
    Current opinion in allergy and clinical immunology, 2012, Volume: 12, Issue:5

    Topics: Animals; Anti-Allergic Agents; Binding, Competitive; Conjunctivitis, Allergic; Histamine; Histamine

2012
Antihistamines in rhinoconjunctivitis.
    Clinical allergy and immunology, 2002, Volume: 17

    Topics: Animals; Conjunctivitis, Allergic; Histamine; Histamine H1 Antagonists; Humans; Receptors, Histamine

2002
H1-antihistamines in the elderly.
    Clinical allergy and immunology, 2002, Volume: 17

    Topics: Aged; Anaphylaxis; Conjunctivitis, Allergic; Histamine; Histamine H1 Antagonists; Humans; Hypersensi

2002
Advances in H1-antihistamines.
    The New England journal of medicine, 2004, Nov-18, Volume: 351, Issue:21

    Topics: Central Nervous System; Conjunctivitis, Allergic; Heart; Histamine; Histamine H1 Antagonists; Humans

2004
[Oral second generation antihistamines in allergic rhinitis].
    Laryngo- rhino- otologie, 2005, Volume: 84, Issue:1

    Topics: Administration, Oral; Adult; Anti-Allergic Agents; Cetirizine; Child; Conjunctivitis, Allergic; Cont

2005
Role of histamine in allergic conjunctivitis.
    Acta ophthalmologica Scandinavica. Supplement, 2000, Issue:230

    Topics: Conjunctivitis, Allergic; Cytokines; Fibroblasts; Histamine; Histamine H1 Antagonists; Humans; Mast

2000
Management of seasonal allergic conjunctivitis (SAC): current therapeutic strategies.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2001, Volume: 31, Issue:6

    Topics: Administration, Topical; Anti-Inflammatory Agents; Conjunctivitis, Allergic; Forecasting; Histamine;

2001

Trials

9 trials available for histamine and Allergic Conjunctivitis

ArticleYear
Evaluating the efficacy of epinastine ophthalmic solution using a conjunctivitis allergen challenge model in patients with birch pollen allergic conjunctivitis.
    Allergology international : official journal of the Japanese Society of Allergology, 2017, Volume: 66, Issue:2

    Topics: Adult; Allergens; Anti-Allergic Agents; Betula; Biomarkers; Conjunctivitis, Allergic; Dibenzazepines

2017
Nasal corticosteroid treatment reduces substance P levels in tear fluid in allergic rhinoconjunctivitis.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2012, Volume: 109, Issue:2

    Topics: Administration, Intranasal; Adrenal Cortex Hormones; Adult; Androstadienes; Antigens, Plant; Conjunc

2012
Double-masked, randomized, placebo-controlled clinical study of the mast cell-stabilizing effects of treatment with olopatadine in the conjunctival allergen challenge model in humans.
    Clinical therapeutics, 2003, Volume: 25, Issue:10

    Topics: Administration, Topical; Adult; Allergens; Conjunctivitis, Allergic; Dibenzoxepins; Double-Blind Met

2003
Extract of Perilla frutescens enriched for rosmarinic acid, a polyphenolic phytochemical, inhibits seasonal allergic rhinoconjunctivitis in humans.
    Experimental biology and medicine (Maywood, N.J.), 2004, Volume: 229, Issue:3

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Chemokine CCL11; Chemokines, CC; Cinnamates; Conjunc

2004
Rapid onset of action of levocabastine eye-drops in histamine-induced conjunctivitis.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1993, Volume: 23, Issue:9

    Topics: Adult; Animals; Chick Embryo; Conjunctivitis, Allergic; Double-Blind Method; Female; Histamine; Hist

1993
Nedocromil sodium and levocabastine reduce the symptoms of conjunctival allergen challenge by different mechanisms.
    The Journal of allergy and clinical immunology, 2001, Volume: 108, Issue:3

    Topics: Adult; Anti-Allergic Agents; Conjunctiva; Conjunctivitis, Allergic; E-Selectin; Female; Histamine; H

2001
Allergic conjunctivitis: a survey of new antihistamines.
    Journal of ocular pharmacology, 1991,Winter, Volume: 7, Issue:4

    Topics: Animals; Conjunctiva; Conjunctivitis, Allergic; Dose-Response Relationship, Drug; Double-Blind Metho

1991
Conjunctival hyperresponsiveness to ocular histamine challenge in patients with vernal conjunctivitis.
    The Journal of allergy and clinical immunology, 1992, Volume: 89, Issue:1 Pt 1

    Topics: Adolescent; Adult; Child; Child, Preschool; Conjunctiva; Conjunctivitis, Allergic; Dose-Response Rel

1992
A double-blind, multicenter immunotherapy trial in children, using a purified and standardized Cladosporium herbarum preparation. I. Clinical results.
    Allergy, 1986, Volume: 41, Issue:2

    Topics: Adolescent; Asthma; Bronchial Provocation Tests; Child; Child, Preschool; Cladosporium; Clinical Tri

1986

Other Studies

59 other studies available for histamine and Allergic Conjunctivitis

ArticleYear
Therapeutic efficacy of topical blockade of substance P in experimental allergic red eye.
    The ocular surface, 2022, Volume: 26

    Topics: Animals; Conjunctiva; Conjunctivitis, Allergic; Eosinophils; Guinea Pigs; Histamine; Substance P

2022
Gp130 Promotes Inflammation via the STAT3/JAK2 Pathway in Allergic Conjunctivitis.
    Investigative ophthalmology & visual science, 2023, 04-03, Volume: 64, Issue:4

    Topics: Animals; Conjunctivitis, Allergic; Cytokine Receptor gp130; Histamine; Inflammation; Janus Kinase 2;

2023
Decreased viability and proliferation of CHANG conjunctival epithelial cells after contact with ultraviolet light-irradiated pollen.
    Cutaneous and ocular toxicology, 2018, Volume: 37, Issue:3

    Topics: Allergens; Alnus; Cell Line; Cell Proliferation; Cell Survival; Conjunctiva; Conjunctivitis, Allergi

2018
Treatment with galectin-1 eye drops regulates mast cell degranulation and attenuates the severity of conjunctivitis.
    European journal of pharmacology, 2018, Aug-15, Volume: 833

    Topics: Animals; Anti-Allergic Agents; Anti-Inflammatory Agents; Cell Degranulation; Cell Movement; Conjunct

2018
Context-Dependent Regulation of Conjunctival Goblet Cell Function by Allergic Mediators.
    Scientific reports, 2018, 08-15, Volume: 8, Issue:1

    Topics: Animals; Cell Proliferation; Conjunctiva; Conjunctival Diseases; Conjunctivitis, Allergic; Cytokines

2018
In vitro and in vivo performance of epinastine hydrochloride-releasing contact lenses.
    PloS one, 2019, Volume: 14, Issue:1

    Topics: Animals; Conjunctivitis, Allergic; Contact Lenses, Hydrophilic; Delayed-Action Preparations; Dibenza

2019
Resolvin D1 and aspirin-triggered resolvin D1 regulate histamine-stimulated conjunctival goblet cell secretion.
    Mucosal immunology, 2013, Volume: 6, Issue:6

    Topics: Animals; Aspirin; Bodily Secretions; Calcium Signaling; Cells, Cultured; Conjunctivitis, Allergic; D

2013
Involvement of chymase in allergic conjunctivitis of guinea pigs.
    Experimental eye research, 2013, Volume: 113

    Topics: Allergens; Animals; Chymases; Conjunctivitis, Allergic; Disease Models, Animal; Enzyme Inhibitors; G

2013
Antiallergic effects of pigments isolated from green sea urchin (Strongylocentrotus droebachiensis) shells.
    Planta medica, 2013, Volume: 79, Issue:18

    Topics: Animal Shells; Animals; Anti-Allergic Agents; Conjunctivitis, Allergic; Dibenzoxepins; Disease Model

2013
Culture medium from TNF-α-stimulated mesenchymal stem cells attenuates allergic conjunctivitis through multiple antiallergic mechanisms.
    The Journal of allergy and clinical immunology, 2015, Volume: 136, Issue:2

    Topics: Ambrosia; Animals; B-Lymphocytes; Bone Marrow Cells; Capillary Permeability; Cell Differentiation; C

2015
A histamine-independent itch pathway is required for allergic ocular itch.
    The Journal of allergy and clinical immunology, 2016, Volume: 137, Issue:4

    Topics: Animals; Biomarkers; Conjunctivitis, Allergic; Histamine; Mice; Mice, Knockout; Pruritus; Transient

2016
[A preliminary study on the role of substance P in histamine-nasal-spray-induced allergic conjunctivitis in guinea pigs].
    Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery, 2015, Volume: 50, Issue:10

    Topics: Animals; Conjunctiva; Conjunctivitis, Allergic; Eosinophils; Guinea Pigs; Histamine; Male; Mast Cell

2015
Treatment with olopatadine and naphazoline hydrochloride reduces allergic conjunctivitis in mice through alterations in inflammation, NGF and VEGF.
    Molecular medicine reports, 2016, Volume: 13, Issue:4

    Topics: Animals; Blotting, Western; Conjunctivitis, Allergic; Cytokines; Disease Models, Animal; Drug Therap

2016
Biomimetic contact lenses eluting olopatadine for allergic conjunctivitis.
    Acta biomaterialia, 2016, 09-01, Volume: 41

    Topics: Amino Acids; Animals; Biomimetic Materials; Cell Line; Cell Survival; Chickens; Conjunctivitis, Alle

2016
Role of histamine H(4) receptor in allergic conjunctivitis in mice.
    European journal of pharmacology, 2009, Apr-17, Volume: 608, Issue:1-3

    Topics: Animals; Conjunctivitis, Allergic; Histamine; Histamine Agonists; Male; Mice; Mice, Inbred ICR; Mole

2009
Bepotastine besilate, a highly selective histamine H(1) receptor antagonist, suppresses vascular hyperpermeability and eosinophil recruitment in in vitro and in vivo experimental allergic conjunctivitis models.
    Experimental eye research, 2010, Volume: 91, Issue:1

    Topics: Animals; Capillary Permeability; Cells, Cultured; Chemotaxis, Leukocyte; Conjunctiva; Conjunctivitis

2010
Relation between cooling sheet effect and tear histamine concenration in allergic conjunctivitis.
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2010, Volume: 130, Issue:7

    Topics: Conjunctivitis, Allergic; Cryotherapy; Enzyme-Linked Immunosorbent Assay; Histamine; Histamine H1 An

2010
Evaluation of histamine-induced conjunctival oedema in guinea pigs by means of image analysis.
    The British journal of ophthalmology, 2010, Volume: 94, Issue:12

    Topics: Animals; Coloring Agents; Conjunctiva; Conjunctivitis, Allergic; Evans Blue; Guinea Pigs; Histamine;

2010
Effect of Perilla frutescens var. acuta Kudo and rosmarinic acid on allergic inflammatory reactions.
    Experimental biology and medicine (Maywood, N.J.), 2011, Volume: 236, Issue:1

    Topics: Animals; Blotting, Western; Cell Line; Cinnamates; Conjunctivitis, Allergic; Cyclooxygenase 2; Cytok

2011
Pre-seasonal treatment with topical olopatadine suppresses the clinical symptoms of seasonal allergic conjunctivitis.
    American journal of ophthalmology, 2011, Volume: 151, Issue:4

    Topics: Administration, Topical; Adult; Conjunctivitis, Allergic; Dibenzoxepins; Female; Histamine; Histamin

2011
Ameliorative effect of thymoquinone on ovalbumin-induced allergic conjunctivitis in Balb/c mice.
    Current eye research, 2011, Volume: 36, Issue:7

    Topics: Animals; Benzoquinones; Chromatography, High Pressure Liquid; Conjunctivitis, Allergic; Cytokines; D

2011
[Allergic mediators in tear from children with seasonal and perennial allergic conjunctivitis].
    Archivos de la Sociedad Espanola de Oftalmologia, 2011, Volume: 86, Issue:6

    Topics: Adolescent; Biomarkers; Child; Child, Preschool; Chitinases; Conjunctivitis, Allergic; E-Selectin; E

2011
Role of histamine and its receptor subtypes in stimulation of conjunctival goblet cell secretion.
    Investigative ophthalmology & visual science, 2012, May-17, Volume: 53, Issue:6

    Topics: Animals; Blotting, Western; Cells, Cultured; Cimetidine; Conjunctiva; Conjunctivitis, Allergic; Dose

2012
Involvement of leukotriene B4 in itching in a mouse model of ocular allergy.
    Experimental eye research, 2012, Volume: 98

    Topics: Allergens; Ambrosia; Animals; Conjunctivitis, Allergic; Disease Models, Animal; Glucocorticoids; His

2012
Effects of nonsteroidal anti-inflammatory drugs on experimental allergic conjunctivitis in Guinea pigs.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2003, Volume: 19, Issue:6

    Topics: Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antigens; Benzophenones;

2003
[The role of histamine in the etiology of allergic conjunctivitis].
    Klinische Monatsblatter fur Augenheilkunde und fur augenarztliche Fortbildung, 1951, Volume: 119, Issue:5

    Topics: Anti-Allergic Agents; Conjunctivitis; Conjunctivitis, Allergic; Histamine; Histamine Agents; Histami

1951
A chronic model for evaluating the itching associated with allergic conjunctivitis in rats.
    International immunopharmacology, 2004, Volume: 4, Issue:1

    Topics: Animals; Anti-Allergic Agents; Antigens; Chronic Disease; Conjunctivitis, Allergic; Disease Models,

2004
Is the menstrual cycle affecting the skin prick test reactivity?
    Asian Pacific journal of allergy and immunology, 2004, Volume: 22, Issue:4

    Topics: Adult; Allergens; Conjunctivitis, Allergic; Estradiol; Female; Follicle Stimulating Hormone; Histami

2004
Effects of multiple dexamethasone treatments on aggravation of allergic conjunctivitis associated with mast cell hyperplasia.
    Biological & pharmaceutical bulletin, 2008, Volume: 31, Issue:3

    Topics: Allergens; Animals; Antigens, Plant; Cell Count; Conjunctivitis, Allergic; Cryptomeria; Dexamethason

2008
Effect of (Z)-11-[3-(dimethylamino) propylidene]-6,11-dihydrodibenz[b,e]oxepin-2-acetic acid hydrochloride on experimental allergic conjunctivitis and rhinitis in rats and guinea pigs.
    Arzneimittel-Forschung, 1995, Volume: 45, Issue:9

    Topics: Administration, Oral; Administration, Topical; Allergens; Animals; Anti-Allergic Agents; Ascaris; Co

1995
Influence of the menstrual cycle on skin-prick test reactions to histamine, morphine and allergen.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1995, Volume: 25, Issue:5

    Topics: Adult; Allergens; Asthma; Conjunctivitis, Allergic; Drug Hypersensitivity; Estrogens; Female; Histam

1995
[Effect of tranilast ophthalmic solution on allergic conjunctivitis in guinea pigs].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1993, Volume: 101, Issue:1

    Topics: Animals; Conjunctiva; Conjunctivitis, Allergic; Cromolyn Sodium; Diphenhydramine; Fluorescein; Fluor

1993
Preclinical efficacy of emedastine, a potent, selective histamine H1 antagonist for topical ocular use.
    Journal of ocular pharmacology, 1994,Winter, Volume: 10, Issue:4

    Topics: Administration, Topical; Anaphylaxis; Animals; Benzimidazoles; Capillary Permeability; Conjunctiva;

1994
Histamine and tryptase levels in allergic conjunctivitis and vernal keratoconjunctivitis.
    Cornea, 1994, Volume: 13, Issue:4

    Topics: Child; Chymases; Conjunctiva; Conjunctivitis, Allergic; Epithelium; Female; Histamine; Humans; Male;

1994
Ocular challenge and hyperresponsiveness to histamine in patients with allergic conjunctivitis.
    The Journal of allergy and clinical immunology, 1993, Volume: 91, Issue:6

    Topics: Adolescent; Adult; Allergens; Cell Adhesion Molecules; Conjunctivitis, Allergic; Eye; Female; Histam

1993
Precision of conjunctival provocation tests in right and left eyes.
    The Journal of allergy and clinical immunology, 1993, Volume: 92, Issue:1 Pt 1

    Topics: Adult; Allergens; Conjunctiva; Conjunctivitis, Allergic; Dose-Response Relationship, Immunologic; Hi

1993
Measurement of interleukin-4 and histamine in superficial cells of conjunctiva in patients with allergic conjunctivitis.
    Current eye research, 1996, Volume: 15, Issue:2

    Topics: Adolescent; Adult; Aged; Allergens; Child; Conjunctiva; Conjunctivitis; Conjunctivitis, Allergic; En

1996
The in vitro and in vivo ocular pharmacology of olopatadine (AL-4943A), an effective anti-allergic/antihistaminic agent.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 1996,Winter, Volume: 12, Issue:4

    Topics: Administration, Topical; Anaphylaxis; Animals; Anti-Allergic Agents; Capillary Permeability; Conjunc

1996
Olopatadine (AL-4943A): ligand binding and functional studies on a novel, long acting H1-selective histamine antagonist and anti-allergic agent for use in allergic conjunctivitis.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 1996,Winter, Volume: 12, Issue:4

    Topics: Anti-Allergic Agents; Binding, Competitive; Cell Line; Cells, Cultured; Conjunctiva; Conjunctivitis,

1996
Interaction between nitric oxide and prostaglandin synthesis in the acute phase of allergic conjunctivitis.
    Prostaglandins, 1996, Volume: 52, Issue:6

    Topics: Administration, Topical; Albumins; Animals; Antigens; Capillary Permeability; Conjunctival Diseases;

1996
Histaminase activity in patients with vernal keratoconjunctivitis.
    Ophthalmology, 1995, Volume: 102, Issue:12

    Topics: Adolescent; Adult; Amine Oxidase (Copper-Containing); Child; Child, Preschool; Conjunctivitis, Aller

1995
Role of substance P in experimental allergic conjunctivitis in guinea pigs.
    Methods and findings in experimental and clinical pharmacology, 1997, Volume: 19, Issue:9

    Topics: Animals; Capillary Permeability; Capsaicin; Conjunctiva; Conjunctivitis, Allergic; Dipeptides; Disea

1997
[Histamine in tears in allergic rhinoconjunctivitis].
    Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 1998, Volume: 95, Issue:4

    Topics: Adolescent; Adult; Conjunctivitis, Allergic; Desensitization, Immunologic; Female; Histamine; Humans

1998
Inhibition of histamine-induced human conjunctival epithelial cell responses by ocular allergy drugs.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1999, Volume: 117, Issue:5

    Topics: Cells, Cultured; Chromatography, Ion Exchange; Conjunctiva; Conjunctivitis, Allergic; Dose-Response

1999
Histamine effects on conjunctival fibroblasts from patients with vernal conjunctivitis.
    Experimental eye research, 1999, Volume: 68, Issue:6

    Topics: Cell Culture Techniques; Cell Division; Conjunctiva; Conjunctivitis, Allergic; Dose-Response Relatio

1999
Tear and serum soluble leukocyte activation markers in conjunctival allergic diseases.
    American journal of ophthalmology, 2000, Volume: 129, Issue:2

    Topics: Adolescent; Adult; Biomarkers; Blood Proteins; Conjunctivitis, Allergic; Conjunctivitis, Bacterial;

2000
Changes in histamine content following pharmacologically-induced mast cell degranulation in the rat conjunctiva.
    Pharmacological research, 2000, Volume: 41, Issue:6

    Topics: Animals; Cell Degranulation; Conjunctiva; Conjunctivitis, Allergic; Cromolyn Sodium; Disease Models,

2000
Experimental allergic conjunctivitis in guinea pigs induced by Japanese cedar pollen.
    Biological & pharmaceutical bulletin, 2000, Volume: 23, Issue:5

    Topics: Animals; Anti-Allergic Agents; Capillary Permeability; Conjunctivitis, Allergic; Disease Models, Ani

2000
Vascular permeability in allergic conjunctivitis in mice lacking histamine H1 receptors.
    European journal of pharmacology, 2000, Dec-15, Volume: 409, Issue:3

    Topics: Animals; Capillary Permeability; Conjunctivitis, Allergic; Free Radical Scavengers; Histamine; Hista

2000
Respiratory syncytial virus may be a pathogen in allergic conjunctivitis.
    Cornea, 2002, Volume: 21, Issue:2 Suppl 1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Conjunctivitis, Allergic; Enzym

2002
CR 2039, a new bis-(1H-tetrazol-5-yl)phenylbenzamide derivative with potential for the topical treatment of asthma.
    European journal of pharmacology, 1992, Dec-08, Volume: 229, Issue:1

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Administration, Inhalation; Anaphylaxis; Animals; Asthma; Benza

1992
Levocabastine: pharmacological profile of a highly effective inhibitor of allergic reactions.
    Agents and actions, 1992, Volume: 35, Issue:1-2

    Topics: Anaphylaxis; Animals; Ascaris; Conjunctivitis, Allergic; Dogs; Guinea Pigs; Histamine; Histamine H1

1992
Inhibitory effect of levocabastine on experimental allergic conjunctivitis in guinea pigs.
    Journal of pharmacobio-dynamics, 1991, Volume: 14, Issue:8

    Topics: Aminopyridines; Animals; Antigens; Capillary Permeability; Conjunctivitis, Allergic; Cromolyn Sodium

1991
Correlation between conjunctival provocation test (CPT) and systemic allergometric tests in allergic conjunctivitis.
    Eye (London, England), 1990, Volume: 4 ( Pt 5)

    Topics: Adolescent; Adult; Allergens; Child; Conjunctiva; Conjunctivitis, Allergic; Female; Histamine; Human

1990
Conjunctival provocative tests: a model of human ocular allergy.
    Transactions of the American Ophthalmological Society, 1989, Volume: 87

    Topics: Adolescent; Adult; Allergens; Body Temperature; Conjunctivitis, Allergic; Female; Histamine; Humans;

1989
Application of histamine-induced conjunctivitis to the assessment of a topical antihistamine, levocabastine.
    International archives of allergy and applied immunology, 1987, Volume: 82, Issue:3-4

    Topics: Administration, Topical; Animals; Conjunctivitis, Allergic; Drug Evaluation, Preclinical; Guinea Pig

1987
Levocabastine. Evaluation in the histamine and compound 48/80 models of ocular allergy in humans.
    Ophthalmology, 1988, Volume: 95, Issue:11

    Topics: Conjunctivitis, Allergic; Histamine; Humans; p-Methoxy-N-methylphenethylamine; Piperidines

1988
The role of leukotriene D4 as a mediator of allergic conjunctivitis in the guinea-pig.
    European journal of pharmacology, 1987, Feb-24, Volume: 134, Issue:3

    Topics: Animals; Capillary Permeability; Conjunctivitis, Allergic; Guinea Pigs; Histamine; Indomethacin; Ket

1987
[Lacrimal level of histamine in allergic conjunctival diseases].
    Arerugi = [Allergy], 1986, Volume: 35, Issue:12

    Topics: Conjunctivitis, Allergic; Histamine; Humans; Tears

1986