hispidin and Prostatic-Neoplasms

hispidin has been researched along with Prostatic-Neoplasms* in 1 studies

Other Studies

1 other study(ies) available for hispidin and Prostatic-Neoplasms

Article	Year
Phenolic compounds with NF-κB inhibitory effects from the fungus Phellinus baumii. Bioorganic & medicinal chemistry letters, 2011, Jun-01, Volume: 21, Issue:11 Chemical investigation of the fungus Phellinus baumii has resulted in characterization of five previously undescribed hispidin derivatives, phellibaumins A-E (1-5), as well as two pairs of new non-equivalent epimeric benzyl dihydroflavones, methylphelligrin A (9), epi-methylphelligrin A (10), methylphelligrin B (11), and epi-methylphelligrin B (12), together with five known compounds, interfungin B (6), phelligridin H (7), phelligridimer A (8), phelligrin A (13), and epi-phelligrin A (14). Phellibaumin A (1) was a novel hispidin derivative with a unique 3,4-dihydroxybenzofuran unit. These compounds exhibited NF-κB inhibitory activity with IC(50) values of 52.96 μM (1), 41.40 μM (2), 52.92 μM (5), 36.44 μM (9 and 10), and 22.46 μM (11 and 12), respectively. Topics: Basidiomycota; Cell Line, Tumor; Chromatography, High Pressure Liquid; Circular Dichroism; Enzyme Activation; Enzyme Inhibitors; Humans; Magnetic Resonance Spectroscopy; Male; Models, Molecular; Molecular Structure; NF-kappa B; Phenols; Prostatic Neoplasms; Pyrones	2011

Article

Year

Phenolic compounds with NF-κB inhibitory effects from the fungus Phellinus baumii.

Bioorganic & medicinal chemistry letters, 2011, Jun-01, Volume: 21, Issue:11

Chemical investigation of the fungus Phellinus baumii has resulted in characterization of five previously undescribed hispidin derivatives, phellibaumins A-E (1-5), as well as two pairs of new non-equivalent epimeric benzyl dihydroflavones, methylphelligrin A (9), epi-methylphelligrin A (10), methylphelligrin B (11), and epi-methylphelligrin B (12), together with five known compounds, interfungin B (6), phelligridin H (7), phelligridimer A (8), phelligrin A (13), and epi-phelligrin A (14). Phellibaumin A (1) was a novel hispidin derivative with a unique 3,4-dihydroxybenzofuran unit. These compounds exhibited NF-κB inhibitory activity with IC(50) values of 52.96 μM (1), 41.40 μM (2), 52.92 μM (5), 36.44 μM (9 and 10), and 22.46 μM (11 and 12), respectively.

Topics: Basidiomycota; Cell Line, Tumor; Chromatography, High Pressure Liquid; Circular Dichroism; Enzyme Activation; Enzyme Inhibitors; Humans; Magnetic Resonance Spectroscopy; Male; Models, Molecular; Molecular Structure; NF-kappa B; Phenols; Prostatic Neoplasms; Pyrones

2011