hippuristanol has been researched along with Lung-Neoplasms* in 1 studies
1 other study(ies) available for hippuristanol and Lung-Neoplasms
| Article | Year |
|---|---|
Synthesis of a new cytotoxic cephalostatin/ritterazine analogue from hecogenin and 22-epi-hippuristanol.
A new cephalostatin/ritterazine analogue was prepared from the commercially available hecogenin acetate and the natural cytotoxic steroid 22-epi-hippuristanol. The method involved the reductive dimerization of enaminoketones (condensation of alpha-aminoketones) and condensation between an enaminoketone and an alpha-hydroxyketone. The new analogue showed higher cytotoxic activity than the cytotoxic 22-epi-hippuristanol against MDA-MB-231, A-549 and HT-29 cultured tumor cell lines. Topics: Antineoplastic Agents; Breast Neoplasms; Carcinoma; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Cytotoxins; Female; Humans; Inhibitory Concentration 50; Lung Neoplasms; Phenazines; Sapogenins; Spiro Compounds; Steroids; Sterols | 2010 |