Page last updated: 2024-10-17

hippuric acid and Kidney Failure, Chronic

hippuric acid has been researched along with Kidney Failure, Chronic in 22 studies

hippuric acid: RN given refers to parent cpd; structure in Merck Index, 9th ed, #4591
N-benzoylglycine : An N-acylglycine in which the acyl group is specified as benzoyl.

Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.

Research Excerpts

ExcerptRelevanceReference
" The uptake of liposomes by direct incubation in vitro showed an obvious dose-response relationship for p-cresyl sulfate (PCS) and indoxyl sulfate (IS) but not for hippuric acid (HA)."1.51Increasing the removal of protein-bound uremic toxins by liposome-supported hemodialysis. ( Ding, F; Li, Y; Liu, T; Ma, S; Shi, Y; Tian, H; Wang, W; Wang, Y; Zhu, Q, 2019)
"In 8 subjects with chronic renal failure treated conservatively the renal hippurate clearance (CHip), polyfructosan (CPF) and creatinine (Ccr) clearance was assessed."1.29[Renal clearance of hippurate in persons with chronic renal insufficiency]. ( Dzúrik, R; Nádvorníková, H; Schück, O; Skibová, J; Spustová, V; Teplan, V, 1994)
"In haemodialysed patients with chronic renal failure, the plasma levels of HA and FA are elevated in comparison with normal controls and hospital patients without kidney diseases: HA, 11."1.28Hippuric acid and 3-carboxy-4-methyl-5-propyl-2-furanpropionic acid in serum and urine. Analytical approaches and clinical relevance in kidney diseases. ( Bubeck, JI; Liebich, HM; Pickert, A; Scheiter, A; Wahl, G, 1990)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19904 (18.18)18.7374
1990's6 (27.27)18.2507
2000's3 (13.64)29.6817
2010's8 (36.36)24.3611
2020's1 (4.55)2.80

Authors

AuthorsStudies
Deguchi, T1
Ohtsuki, S1
Otagiri, M1
Takanaga, H1
Asaba, H1
Mori, S1
Terasaki, T1
Stanimirova, I1
Banasik, M1
Ząbek, A1
Dawiskiba, T1
Kościelska-Kasprzak, K1
Wojtowicz, W1
Krajewska, M1
Janczak, D1
Młynarz, P1
Shafi, T2
Sirich, TL2
Meyer, TW3
Hostetter, TH3
Plummer, NS2
Hwang, S2
Melamed, ML2
Banerjee, T2
Coresh, J2
Powe, NR2
Shi, Y1
Wang, Y1
Ma, S1
Liu, T1
Tian, H1
Zhu, Q1
Wang, W1
Li, Y1
Ding, F1
Lin, YT1
Wu, PH1
Lee, HH1
Mubanga, M1
Chen, CS1
Kuo, MC1
Chiu, YW1
Kuo, PL1
Hwang, SJ1
Tsujimoto, M1
Nagano, Y1
Hosoda, S1
Shiraishi, A1
Miyoshi, A1
Hiraoka, S1
Furukubo, T1
Izumi, S1
Yamakawa, T1
Minegaki, T1
Nishiguchi, K1
Funk, BA1
Parekh, RS1
Kikuchi, K2
Itoh, Y2
Tateoka, R2
Ezawa, A2
Murakami, K2
Niwa, T3
Nishio, T1
Takamura, N1
Nishii, R1
Tokunaga, J1
Yoshimoto, M1
Kawai, K1
Liebich, HM4
Pickert, A3
Tetschner, B2
Mitch, WE1
Brusilow, S1
Schück, O1
Spustová, V3
Dzúrik, R3
Teplan, V1
Nádvorníková, H1
Skibová, J1
Lim, CF1
Bernard, BF1
de Jong, M1
Docter, R1
Krenning, EP1
Hennemann, G1
Krivosíková, Z1
Gazdíková, K1
Krämer, BK1
Hohmann, C1
Müller, GA1
Hablitzel, M1
Risler, T2
Gajdos, M1
Opatrný, K1
Stefíková, K1
Bubeck, JI1
Wahl, G1
Scheiter, A1
Schoots, AC1
De Vries, PM1
Thiemann, R1
Hazejager, WA1
Visser, SL1
Oe, PL1
Fischer, U1
Rapp, K1
Eggstein, M1

Reviews

1 review available for hippuric acid and Kidney Failure, Chronic

ArticleYear
Organic acids and the uremic syndrome: protein metabolite hypothesis in the progression of chronic renal failure.
    Seminars in nephrology, 1996, Volume: 16, Issue:3

    Topics: Animals; Furans; Hippurates; Humans; Indoles; Kidney Failure, Chronic; Propionates; Protein Binding;

1996

Trials

3 trials available for hippuric acid and Kidney Failure, Chronic

ArticleYear
Results of the HEMO Study suggest that p-cresol sulfate and indoxyl sulfate are not associated with cardiovascular outcomes.
    Kidney international, 2017, Volume: 92, Issue:6

    Topics: Adult; Aged; Cardiovascular Diseases; Cresols; Female; Glutamine; Hippurates; Humans; Indican; Kidne

2017
Influences of haemodialysis on the binding sites of human serum albumin: possibility of an efficacious administration plan using binding inhibition.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2008, Volume: 23, Issue:7

    Topics: Adult; Aged; Barbiturates; Binding Sites; Carbon Radioisotopes; Diazepam; Diuretics; Fatty Acids, No

2008
In vivo clearance and elimination of nine marker substances during hemofiltration with different membranes.
    The International journal of artificial organs, 1992, Volume: 15, Issue:7

    Topics: Aged; beta 2-Microglobulin; Creatinine; Dialysis Solutions; Hemofiltration; Hippurates; Humans; Kidn

1992

Other Studies

18 other studies available for hippuric acid and Kidney Failure, Chronic

ArticleYear
Major role of organic anion transporter 3 in the transport of indoxyl sulfate in the kidney.
    Kidney international, 2002, Volume: 61, Issue:5

    Topics: Animals; Anions; Biological Transport; Dose-Response Relationship, Drug; Female; Furans; Indican; Ki

2002
Serum metabolomics approach to monitor the changes in metabolite profiles following renal transplantation.
    Scientific reports, 2020, 10-14, Volume: 10, Issue:1

    Topics: Alanine; Biomarkers; Health Status; Hippurates; Humans; Kidney Failure, Chronic; Kidney Transplantat

2020
Increasing the removal of protein-bound uremic toxins by liposome-supported hemodialysis.
    Artificial organs, 2019, Volume: 43, Issue:5

    Topics: Animals; Cresols; Dialysis Solutions; Equipment Design; Hippurates; Indican; Kidney Failure, Chronic

2019
Indole-3 acetic acid increased risk of impaired cognitive function in patients receiving hemodialysis.
    Neurotoxicology, 2019, Volume: 73

    Topics: Aged; Biomarkers; Blood-Brain Barrier; Brain; Capillary Permeability; Cognition; Cognitive Dysfuncti

2019
Effects of decreased vitamin D and accumulated uremic toxin on human CYP3A4 activity in patients with end-stage renal disease.
    Toxins, 2013, Aug-19, Volume: 5, Issue:8

    Topics: Cell Line, Tumor; Cytochrome P-450 CYP3A; Erythromycin; Furans; Hippurates; Humans; Indican; Indolea

2013
Prominent accumulation in hemodialysis patients of solutes normally cleared by tubular secretion.
    Journal of the American Society of Nephrology : JASN, 2014, Volume: 25, Issue:3

    Topics: Aged; Aged, 80 and over; Biomarkers; Case-Control Studies; Cresols; Female; Glutamine; Hippurates; H

2014
Free Levels of Selected Organic Solutes and Cardiovascular Morbidity and Mortality in Hemodialysis Patients: Results from the Retained Organic Solutes and Clinical Outcomes (ROSCO) Investigators.
    PloS one, 2015, Volume: 10, Issue:5

    Topics: Adult; Aged; Biomarkers; Cardiovascular Diseases; Cause of Death; Cresols; Female; Glutamine; Hippur

2015
Metabolomic analysis of uremic toxins by liquid chromatography/electrospray ionization-tandem mass spectrometry.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2010, Jun-15, Volume: 878, Issue:20

    Topics: Animals; Chromatography, Liquid; Cresols; Disease Models, Animal; Hippurates; Humans; Indican; Kidne

2010
Metabolomic search for uremic toxins as indicators of the effect of an oral sorbent AST-120 by liquid chromatography/tandem mass spectrometry.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2010, Nov-01, Volume: 878, Issue:29

    Topics: Adsorption; Animals; Carbon; Chromatography, Liquid; Hippurates; Indican; Kidney Failure, Chronic; M

2010
Gas chromatographic and gas chromatographic-mass spectrometric analysis of organic acids in plasma of patients with chronic renal failure.
    Journal of chromatography, 1984, Apr-27, Volume: 289

    Topics: Adolescent; Adult; Aged; Carboxylic Acids; Chromatography, Gas; Female; Furans; Gas Chromatography-M

1984
Benzoate-induced changes in glycine and urea metabolism in patients with chronic renal failure.
    The Journal of pharmacology and experimental therapeutics, 1982, Volume: 222, Issue:3

    Topics: Benzoates; Benzoic Acid; Female; Glomerular Filtration Rate; Glycine; Hippurates; Humans; Kidney Fai

1982
[Renal clearance of hippurate in persons with chronic renal insufficiency].
    Vnitrni lekarstvi, 1994, Volume: 40, Issue:7

    Topics: Adult; Creatinine; Female; Fructans; Glomerular Filtration Rate; Hippurates; Humans; Kidney; Kidney

1994
A furan fatty acid and indoxyl sulfate are the putative inhibitors of thyroxine hepatocyte transport in uremia.
    The Journal of clinical endocrinology and metabolism, 1993, Volume: 76, Issue:2

    Topics: Adsorption; Animals; Biological Transport; Cells, Cultured; Furans; Hippurates; Humans; Indican; Iod

1993
Hippurate participates in the correction of metabolic acidosis.
    Kidney international. Supplement, 2001, Volume: 78

    Topics: Acid-Base Equilibrium; Acidosis; Ammonia; Animals; Glutaminase; Hippurates; Humans; Kidney; Kidney F

2001
Serum hippurate and its excretion in conservatively treated and dialysed patients with chronic renal failure.
    Physiological research, 1991, Volume: 40, Issue:6

    Topics: Hippurates; Humans; Kidney Failure, Chronic; Osmolar Concentration; Reference Values; Renal Dialysis

1991
Hippuric acid and 3-carboxy-4-methyl-5-propyl-2-furanpropionic acid in serum and urine. Analytical approaches and clinical relevance in kidney diseases.
    Journal of chromatography, 1990, Feb-02, Volume: 500

    Topics: Chromatography, Gas; Chromatography, High Pressure Liquid; Furans; Hemofiltration; Hippurates; Human

1990
Biochemical and neurophysiological parameters in hemodialyzed patients with chronic renal failure.
    Clinica chimica acta; international journal of clinical chemistry, 1989, Oct-31, Volume: 185, Issue:1

    Topics: Calcium; Chromatography, High Pressure Liquid; Hemoglobins; Hippurates; Humans; Kidney Failure, Chro

1989
Gas chromatographic determination of hippuric acid and a furancarboxylic acid in plasma of patients with kidney diseases.
    Journal of chromatography, 1987, Jul-24, Volume: 399

    Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Creatinine; Female; Furans; Hippurates; Humans; Ki

1987