Page last updated: 2024-10-17

hippuric acid and Aging

hippuric acid has been researched along with Aging in 7 studies

hippuric acid: RN given refers to parent cpd; structure in Merck Index, 9th ed, #4591
N-benzoylglycine : An N-acylglycine in which the acyl group is specified as benzoyl.

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research Excerpts

ExcerptRelevanceReference
"Hippuric acid (HA) is a metabolite resulting from the hepatic glycine conjugation of benzoic acid (BA) or from the gut bacterial metabolism of phenylalanine."7.01Disentangling the Complexity of Nutrition, Frailty and Gut Microbial Pathways during Aging: A Focus on Hippuric Acid. ( Guerra, A; Maggi, S; Meschi, T; Nouvenne, A; Ticinesi, A, 2023)
"The association between hippurate excretion and antioxidant biomarkers along with the relationship between phenylacetylglycine excretion and oxidant biomarkers suggests that the long-term consumption of a Med + CoQ diet could be beneficial for healthy aging and a promising challenge in the prevention of processes related to chronic oxidative stress, such as cardiovascular and neurodegenerative disease."5.20Effects of the Mediterranean diet supplemented with coenzyme q10 on metabolomic profiles in elderly men and women. ( Brennan, L; Camargo, A; Delgado-Casado, N; Delgado-Lista, J; Garcia-Rios, A; González-Guardia, L; López-Miranda, J; Marin, C; Perez-Jimenez, F; Perez-Martinez, P; Roche, HM; Yubero-Serrano, EM, 2015)
"Hippuric acid (HA) is a metabolite resulting from the hepatic glycine conjugation of benzoic acid (BA) or from the gut bacterial metabolism of phenylalanine."3.01Disentangling the Complexity of Nutrition, Frailty and Gut Microbial Pathways during Aging: A Focus on Hippuric Acid. ( Guerra, A; Maggi, S; Meschi, T; Nouvenne, A; Ticinesi, A, 2023)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19902 (28.57)18.7374
1990's3 (42.86)18.2507
2000's0 (0.00)29.6817
2010's1 (14.29)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Ticinesi, A1
Guerra, A1
Nouvenne, A1
Meschi, T1
Maggi, S1
González-Guardia, L1
Yubero-Serrano, EM1
Delgado-Lista, J1
Perez-Martinez, P1
Garcia-Rios, A1
Marin, C1
Camargo, A1
Delgado-Casado, N1
Roche, HM1
Perez-Jimenez, F1
Brennan, L1
López-Miranda, J1
STERN, K1
HINDS, EG1
ASKONAS, BA1
BRANDT, IK1
Temellini, A1
Mogavero, S2
Giulianotti, PC1
Pietrabissa, A1
Mosca, F1
Pacifici, GM2
Giuliani, L1
Rane, A1
Bell, JD1
Sadler, PJ1
Morris, VC1
Levander, OA1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Impact of Infant Feeding on Newborn Metabolomic Profile[NCT01606683]30 participants (Actual)Interventional2012-04-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for hippuric acid and Aging

ArticleYear
Disentangling the Complexity of Nutrition, Frailty and Gut Microbial Pathways during Aging: A Focus on Hippuric Acid.
    Nutrients, 2023, Feb-24, Volume: 15, Issue:5

    Topics: Aged; Aging; Biomarkers; Child; Frailty; Gastrointestinal Microbiome; Humans

2023

Trials

1 trial available for hippuric acid and Aging

ArticleYear
Effects of the Mediterranean diet supplemented with coenzyme q10 on metabolomic profiles in elderly men and women.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 2015, Volume: 70, Issue:1

    Topics: Aged; Aging; Antioxidants; beta Carotene; Biomarkers; Cross-Over Studies; Diet, Mediterranean; Dieta

2015

Other Studies

5 other studies available for hippuric acid and Aging

ArticleYear
Ageing and detoxication; studies in hippuric acid synthesis during psychoses of the involutional and old age group.
    The American journal of psychiatry, 1945, Volume: 102

    Topics: Aging; Alzheimer Disease; Hippurates; Humans; Liver; Liver Function Tests; Mental Disorders; Psychot

1945
THE DEVELOPMENT OF THE HIPPURIC ACID-SYNTHESIZING SYSTEM IN THE RAT.
    Developmental biology, 1964, Volume: 10

    Topics: 4-Aminobenzoic Acid; Adrenalectomy; Aging; Animals; Animals, Newborn; Female; Fetus; Glycine; Hippur

1964
Conjugation of benzoic acid with glycine in human liver and kidney: a study on the interindividual variability.
    Xenobiotica; the fate of foreign compounds in biological systems, 1993, Volume: 23, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Aging; Benzoates; Benzoic Acid; Female; Glycine; Hippurates; Humans;

1993
Conjugation of benzoic acid with glycine in the human fetal and adult liver and kidney.
    Developmental pharmacology and therapeutics, 1991, Volume: 17, Issue:1-2

    Topics: Acyltransferases; Adult; Aged; Aging; Benzoates; Benzoic Acid; Culture Techniques; Female; Fetus; Gl

1991
Effect of aging and diet on proton NMR spectra of rat urine.
    Magnetic resonance in medicine, 1991, Volume: 17, Issue:2

    Topics: Aging; Animals; Caseins; Citrates; Citric Acid; Creatinine; Diet; Glycoproteins; Hippurates; Hydroge

1991