hinokinin has been researched along with Pain* in 2 studies
2 other study(ies) available for hinokinin and Pain
| Article | Year |
|---|---|
Antinociceptive Effect of Hinokinin and Kaurenoic Acid Isolated from
Topics: 4-Butyrolactone; Analgesics; Animals; Aristolochia; Benzodioxoles; Chromatography, High Pressure Liquid; Diterpenes; Lignans; Magnetic Resonance Spectroscopy; Male; Mice; Pain; Pain Measurement; Plant Extracts | 2020 |
Analgesic activity of affinin, an alkamide from Heliopsis longipes (Compositae).
Heliopsis longipes (Compositae) is a Mexican plant used as analgesic in pain toothache. A solution of 10mug/ml of dichloromethane extract from this plant showed analgesic activity determined by means of GABA release in mice brain slices. Through a bioassay-directed separation, fractions G-1, G-2, G-4 and G-6 at the same concentration were active. Affinin was the unique and common active compound, and evoke the GABA release 0.5min after administration at 1x10(-4)M concentration. Inactive compound were undeca-2E-en-8,10-dyinoic acid isobutylamide, hinokinin, 2'-hydroxyhinokinin, 3beta-sn-glyceroyl-(1''-palmitoxy)urs-12-ene, 13(18)-ursen-3beta-ol, 13(18)-ursen-3beta-acetate, beta-sitosterol and stigmasterol. The analgesic activity of Heliopsis longipes could be associated to affinin. Topics: 4-Butyrolactone; Alkenes; Amides; Analgesics; Animals; Asteraceae; Benzodioxoles; Brain; Dioxoles; Female; gamma-Aminobutyric Acid; In Vitro Techniques; Lignans; Medicine, Traditional; Methylene Chloride; Mexico; Mice; Pain; Plant Extracts; Plants, Medicinal; Polyunsaturated Alkamides | 2007 |