himastatin has been researched along with Leukemia-P388* in 1 studies
1 other study(ies) available for himastatin and Leukemia-P388
Article | Year |
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Himastatin, a new antitumor antibiotic from Streptomyces hygroscopicus. I. Taxonomy of producing organism, fermentation and biological activity.
Strain C39108-P210-51 (ATCC 53653), an actinomycete isolated from a soil sample collected in India, was found to produce a new antitumor antibiotic, designated himastatin. Taxonomic studies on its morphological, cultural and physiological characteristics identified this producing strain as Streptomyces hygroscopicus C39108-P210-51. Himastatin shows antimicrobial activity against Gram-positive bacteria but it is inactive against Gram-negative bacteria. Himastatin prolongs the life span of mice inoculated with P388 leukemia and B16 melanoma cells. Topics: Animals; Antibiotics, Antineoplastic; Fermentation; Gram-Positive Bacteria; Leukemia P388; Melanoma, Experimental; Mice; Peptides, Cyclic; Soil Microbiology; Streptomyces | 1990 |