higenamine has been researched along with Disease Models, Animal in 9 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 5 (55.56) | 2.80 |
| Authors | Studies |
|---|---|
| Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV | 1 |
| Athari, SS; Du, J; Mehrabi Nasab, E; Qian, L | 1 |
| Hu, Y; Jiang, Y; Shao, XX; Xiao, HY; Xu, Y | 1 |
| Li, H; Li, R; Liu, H; Wang, J; Wang, L; Wang, R; Wei, S; Wen, J; Zhang, L; Zhao, Y; Zou, W | 1 |
| Deng, T; Deng, X; Fu, Q; Gael, A; Hang, L; Lai, J; Li, Z; Liu, Y; Wei, Z; Yan, Q | 1 |
| Li, J; Li, M; Wang, Y; Wu, J; Zhang, Z | 1 |
| Chang, KC; Kim, DH; Lee, DH; Lee, JH; Moon, JC; Pyo, MK; Yun-Choi, HS | 1 |
| Chang, KC; Lee, DH; Park, KM; Pyo, MK; Yun-Choi, HS | 1 |
| Chang, KC; Lee, DH; Pyo, MK; Yun-Choi, HS | 1 |
9 other study(ies) available for higenamine and Disease Models, Animal
| Article | Year |
|---|---|
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection | 2020 |
Bronchodilatory effect of higenamine as antiallergic asthma treatment.
Topics: Animals; Anti-Allergic Agents; Asthma; Cytokines; Disease Models, Animal; Immunoglobulin E; Inflammation; Leukotriene B4; Leukotriene C4; Lung; Mice; Mice, Inbred BALB C; Mucoproteins; Respiratory Hypersensitivity | 2022 |
Higenamine improves DSS-induced ulcerative colitis in mice through the Galectin-3/TLR4/NF-κB pathway.
Topics: Animals; Colitis, Ulcerative; Colon; Dextran Sulfate; Disease Models, Animal; Galectin 3; Inflammation; Mice; Mice, Inbred C57BL; NF-kappa B; Toll-Like Receptor 4 | 2023 |
Therapeutic effects of higenamine combined with [6]-gingerol on chronic heart failure induced by doxorubicin via ameliorating mitochondrial function.
Topics: Aconitum; Alkaloids; Animals; Cardiotoxicity; Catechols; Chronic Disease; Disease Models, Animal; Doxorubicin; Energy Metabolism; Fatty Alcohols; Heart; Heart Failure; Male; Mitochondrial Diseases; Myocytes, Cardiac; Rats; Tetrahydroisoquinolines | 2020 |
Higenamine Improves Cardiac and Renal Fibrosis in Rats With Cardiorenal Syndrome via ASK1 Signaling Pathway.
Topics: Alkaloids; Animals; Cardio-Renal Syndrome; Cells, Cultured; Collagen; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Fibrosis; Kidney; Male; MAP Kinase Kinase Kinase 5; Myocytes, Cardiac; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Rats, Sprague-Dawley; Signal Transduction; Tetrahydroisoquinolines | 2020 |
Higenamine promotes M2 macrophage activation and reduces Hmgb1 production through HO-1 induction in a murine model of spinal cord injury.
Topics: Adoptive Transfer; Alkaloids; Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Heme Oxygenase-1; HMGB1 Protein; Macrophage Activation; Macrophages, Peritoneal; Male; Membrane Proteins; Mice, Inbred C57BL; Motor Activity; Spinal Cord Injuries; Tetrahydroisoquinolines; Time Factors | 2014 |
Enantioselective synthesis of (R)-(+)- and (S)-(-)-higenamine and their analogues with effects on platelet aggregation and experimental animal model of disseminated intravascular coagulation.
Topics: Alkaloids; Amides; Animals; Catalysis; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Disease Models, Animal; Disseminated Intravascular Coagulation; Drug Design; Epinephrine; Inhibitory Concentration 50; Models, Chemical; Platelet Aggregation; Rats; Stereoisomerism; Tetrahydroisoquinolines | 2008 |
Antithrombotic effects of YS-49 and YS-51--1-naphthylmethyl analogs of higenamine.
Topics: Alkaloids; Animals; Disease Models, Animal; Fibrinolytic Agents; Humans; Inhibitory Concentration 50; Isoquinolines; Mice; Mice, Inbred ICR; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Tetrahydroisoquinolines; Thrombosis; Treatment Outcome | 2001 |
The effects of higenamine on LPS-induced experimental disseminated intravascular coagulation (DIC) in rats.
Topics: Alkaloids; Animals; Aspartate Aminotransferases; Blood Urea Nitrogen; Disease Models, Animal; Disseminated Intravascular Coagulation; Dose-Response Relationship, Drug; Fibrin; Fibrinogen; Injections, Intravenous; Lipopolysaccharides; Male; Multiple Organ Failure; Partial Thromboplastin Time; Plant Roots; Platelet Count; Prothrombin Time; Ranunculaceae; Rats; Tetrahydroisoquinolines | 2002 |