Page last updated: 2024-10-28

hexoprenaline and Labor, Premature

hexoprenaline has been researched along with Labor, Premature in 34 studies

Hexoprenaline: Stimulant of adrenergic beta 2 receptors. It is used as a bronchodilator, antiasthmatic agent, and tocolytic agent.

Research Excerpts

ExcerptRelevanceReference
"Sixty white women with preterm labor between 24 and 34 weeks' gestation were treated for 48 hours with intravenous hexoprenaline."2.71Arg16 homozygosity of the beta2-adrenergic receptor improves the outcome after beta2-agonist tocolysis for preterm labor. ( Antonarakis, SE; Blouin, JL; Landau, R; Morales, MA; Smiley, RM, 2005)
"Preterm birth is a major contributor to perinatal mortality and morbidity worldwide."2.50Betamimetics for inhibiting preterm labour. ( Dowswell, T; Neilson, JP; West, HM, 2014)
"Hexoprenaline is a selective beta 2-mimetic drug used in tocology for the prevention of premature labor and immature birth."1.27[Hexoprenaline--a new tocolytic for treatment of premature labor]. ( Heilmann, L; Siekmann, U, 1985)
"3 microgram/min = dosage for massive tocolysis) the uterine activity decreased on average by 73."1.26[Intrauterine pressure and fetal and maternal heart rate on administration of the betamimetic agent, hexoprenaline during labour (author's transl)]. ( Bernaschek, G; Hondros, K; Schaller, A, 1981)
" The dosage varied according to the obstetrical situation and the resultant indication for tocolysis."1.26[Hexoprenalin as a tocolytic drug (author's transl)]. ( Reinold, E, 1979)
" The dosage varied according to the obstetrical situation and the resultant indication for tocolysis."1.26[Hexoprenalin as a tocolytic drug (author's transl)]. ( Reinold, E, 1979)

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-199019 (55.88)18.7374
1990's7 (20.59)18.2507
2000's4 (11.76)29.6817
2010's4 (11.76)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hösli, I1
Sperschneider, C1
Drack, G1
Zimmermann, R1
Surbek, D1
Irion, O1
Neilson, JP2
West, HM1
Dowswell, T1
Lazarov, N1
Lazarov, L1
Lazarov, S1
Mayer, M1
Minichmayr, A1
Klement, F1
Hroncek, K1
Wertaschnigg, D1
Arzt, W1
Wiesinger-Eidenberger, G1
Lechner, E1
Hrubý, K1
Anotayanonth, S1
Subhedar, NV1
Garner, P1
Harigopal, S1
Zhong, XY1
Holzgreve, W1
Hoesli, I1
Hahn, S1
Landau, R1
Morales, MA1
Antonarakis, SE1
Blouin, JL1
Smiley, RM1
Rush, RW1
Siekmann, U2
Heilmann, L2
Brodde, OE1
Gummerus, M2
Frederiksen, MC1
Toig, RM1
Depp, R1
Conradt, A1
Weidinger, H1
Bodenstein, J1
Lechner, W2
Dienstl, F1
Poewe, W1
Daxenbichler, G1
Haukkamaa, M1
Staudach, A2
Bernaschek, G1
Hondros, K1
Schaller, A1
Frigo, P1
Eppel, W2
Frank, A1
Ulm, M1
Golaszewski, T1
Gruber, W1
Strizhakov, AN1
Medvedev, MV1
Kovaleva, LG1
Strizhova, NV1
Hamdan, S1
Tuminova, SN1
Komarova, EE1
Spitzer, D1
Zajc, M1
Heiss, O1
Steiner, H1
Woytoń, J1
Zimmer, M1
Fuchs, T1
Hurwitz, MB1
Reinold, E2
Lipshitz, J1
Haus, M1
Baillie, P1
Vavra, N1
Sevelda, P1
Fitz, R1
Fuchs, AR1
Fuchs, F1
Husslein, P1
van Iddekinge, B1
Gobetz, L1
Seaward, PG1
Hofmeyr, GJ1
Francioli, M1
De Meuron, A1
Mursch, G1
Trittenwein, G1
Rosegger, H1
Beitzke, A1
Lichtenegger, W1
Rosanelli, K1
Zeichen, HL1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparing Fetal Cerebral Blood Flow Between Magnesium Sulfate & Calcium Channel Blockers in Patients With Preterm Labor; a Randomized Controlled Trial.[NCT02591004]Phase 2/Phase 3130 participants (Actual)Interventional2015-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for hexoprenaline and Labor, Premature

ArticleYear
Tocolysis for preterm labor: expert opinion.
    Archives of gynecology and obstetrics, 2014, Volume: 289, Issue:4

    Topics: Anti-Bacterial Agents; Bed Rest; Calcium Channel Blockers; Cervical Length Measurement; Contraindica

2014
Betamimetics for inhibiting preterm labour.
    The Cochrane database of systematic reviews, 2014, Feb-05, Issue:2

    Topics: Adrenergic beta-Agonists; Female; Fenoterol; Hexoprenaline; Humans; Obstetric Labor, Premature; Preg

2014
Betamimetics for inhibiting preterm labour.
    The Cochrane database of systematic reviews, 2004, Oct-18, Issue:4

    Topics: Adrenergic beta-Agonists; Female; Fenoterol; Hexoprenaline; Humans; Obstetric Labor, Premature; Preg

2004

Trials

3 trials available for hexoprenaline and Labor, Premature

ArticleYear
Arg16 homozygosity of the beta2-adrenergic receptor improves the outcome after beta2-agonist tocolysis for preterm labor.
    Clinical pharmacology and therapeutics, 2005, Volume: 78, Issue:6

    Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Adult; Alleles; Amino Acid Substituti

2005
[Tocolysis with hexoprenalin and salbutamol in a clinical comparison].
    Geburtshilfe und Frauenheilkunde, 1983, Volume: 43, Issue:3

    Topics: Albuterol; Birth Weight; Female; Hexoprenaline; Humans; Infant, Newborn; Obstetric Labor, Premature;

1983
[The use of Gynipral (hexoprenaline) in suppression of uterus contractions].
    Ginekologia polska, 1999, Volume: 70, Issue:12

    Topics: Administration, Oral; Female; Hexoprenaline; Humans; Injections, Intravenous; Obstetric Labor, Prema

1999

Other Studies

28 other studies available for hexoprenaline and Labor, Premature

ArticleYear
[Effective tocolysis without β-agonists].
    Akusherstvo i ginekologiia, 2014, Volume: 53 Suppl 2

    Topics: Adrenergic beta-2 Receptor Agonists; Calcium Channel Blockers; Female; Hexoprenaline; Humans; Magnes

2014
Tocolysis with the β-2-sympathomimetic hexoprenaline increases occurrence of infantile haemangioma in preterm infants.
    Archives of disease in childhood. Fetal and neonatal edition, 2013, Volume: 98, Issue:2

    Topics: Adrenergic beta-2 Receptor Agonists; Female; Glucocorticoids; Hemangioma; Hexoprenaline; Humans; Inf

2013
[Comparison of the cost of treatment of premature labor with atosiban or beta-sympathomimetics from the perspective of the health care payer--a pharmacoeconomic model].
    Ceska gynekologie, 2004, Volume: 69, Issue:2

    Topics: Czech Republic; Drug Costs; Female; Fenoterol; Health Care Costs; Hexoprenaline; Humans; Insurance,

2004
Circulatory corticotropin-releasing hormone mRNA concentrations are increased in women with preterm delivery but not in those who respond to tocolytic treatment.
    Clinical chemistry, 2005, Volume: 51, Issue:3

    Topics: Corticotropin-Releasing Hormone; Female; Fetus; Gestational Age; Hexoprenaline; Humans; Obstetric La

2005
The management of preterm labour with intact membranes.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1980, Oct-25, Volume: 58, Issue:17

    Topics: Adrenergic beta-Agonists; Calcium; Ethanol; Extraembryonic Membranes; Female; Fenoterol; Hexoprenali

1980
[Maternal and fetal hemodynamics under simultaneous beta stimulation and beta1 blockade in a tocolysis model. Considerations on status of the neonatal beta receptor and transplacental passage of metoprolol].
    Arzneimittel-Forschung, 1984, Volume: 34, Issue:9

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Cyclic AMP; Female; Fetal Blood; Fetus

1984
Atrial fibrillation during hexoprenaline therapy for premature labor.
    American journal of obstetrics and gynecology, 1983, Jan-01, Volume: 145, Issue:1

    Topics: Adult; Atrial Fibrillation; Female; Hexoprenaline; Humans; Infant, Newborn; Infusions, Parenteral; O

1983
[Tocolysis in emergency cerclage (own technical procedure, prognosis) (author's transl)].
    Geburtshilfe und Frauenheilkunde, 1982, Volume: 42, Issue:4

    Topics: Adult; Amnion; Chorion; Emergencies; Ethanolamines; Female; Fenoterol; Hexoprenaline; Humans; Obstet

1982
[Myoglobin increase during tocolysis (author's transl)].
    Wiener klinische Wochenschrift, 1980, Jul-04, Volume: 92, Issue:14

    Topics: Adult; Female; Heart Rate; Hexoprenaline; Humans; Myoglobin; Obstetric Labor, Premature; Phenethylam

1980
Decrease of serum oestriol during intravenous hexoprenaline or salbutamol treatment.
    British journal of obstetrics and gynaecology, 1982, Volume: 89, Issue:11

    Topics: Adult; Albuterol; Estriol; Female; Fetal Monitoring; Hexoprenaline; Humans; Infusions, Parenteral; O

1982
[Tocolysis in imminent premature delivery: limits of indication--assessment of success--sources of error (author's transl)].
    Zeitschrift fur Geburtshilfe und Perinatologie, 1981, Volume: 185, Issue:2

    Topics: Adult; Female; Fetal Organ Maturity; Gestational Age; Hexoprenaline; Humans; Infant, Newborn; Lung;

1981
[Intrauterine pressure and fetal and maternal heart rate on administration of the betamimetic agent, hexoprenaline during labour (author's transl)].
    Wiener klinische Wochenschrift, 1981, Sep-18, Volume: 93, Issue:17

    Topics: Blood Pressure; Female; Fetal Heart; Heart Rate; Hexoprenaline; Humans; Obstetric Labor, Premature;

1981
Management of supraventricular tachycardia during hexoprenaline therapy for preterm labour: benefit of cardioselective beta blockade?
    Gynecologic and obstetric investigation, 1995, Volume: 39, Issue:3

    Topics: Adult; Female; Hexoprenaline; Humans; Metoprolol; Obstetric Labor, Premature; Pregnancy; Tachycardia

1995
[Uterine-placental-fetal blood flow and fetal cardiac activity during the ginipral treatment of premature labor].
    Akusherstvo i ginekologiia, 1993, Issue:2

    Topics: Abortion, Threatened; Adult; Drug Evaluation; Female; Fetal Heart; Fetus; Hexoprenaline; Humans; Obs

1993
[The use of ginipral (hexoprenaline) in threatened premature labor, acute fetal hypoxia and uncoordinated labor activity].
    Akusherstvo i ginekologiia, 1993, Issue:2

    Topics: Acute Disease; Cardiovascular System; Drug Evaluation; Female; Fetal Hypoxia; Heart Rate, Fetal; Hex

1993
[Tocolysis with hexoprenaline in premature rupture of fetal membranes. Effectiveness and treatment costs].
    Gynakologisch-geburtshilfliche Rundschau, 1993, Volume: 33 Suppl 1

    Topics: Betamethasone; Cost-Benefit Analysis; Female; Fetal Membranes, Premature Rupture; Fetal Organ Maturi

1993
Quadruplets delivered by caesarean section.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1979, May-26, Volume: 55, Issue:22

    Topics: Adult; Cesarean Section; Female; Hexoprenaline; Humans; Obstetric Labor, Premature; Pregnancy; Pregn

1979
[Hexoprenalin as a tocolytic drug (author's transl)].
    Wiener klinische Wochenschrift, 1979, Dec-07, Volume: 91, Issue:23

    Topics: Chemical Phenomena; Chemistry; Female; Fetal Heart; Heart Rate; Hexoprenaline; Humans; Obstetric Lab

1979
[Hexoprenalin as a tocolytic drug (author's transl)].
    Wiener klinische Wochenschrift, 1979, Volume: 91, Issue:23

    Topics: Female; Fetal Heart; Heart Rate; Hexoprenaline; Humans; Infusions, Parenteral; Obstetric Labor, Prem

1979
Preventing premature delivery.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1977, Dec-31, Volume: 52, Issue:28

    Topics: Amniocentesis; Female; Hexoprenaline; Humans; Obstetric Labor, Premature; Phenethylamines; Pregnancy

1977
Reversal of active labour. A case report.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1978, Sep-16, Volume: 54, Issue:12

    Topics: Adult; Female; Hexoprenaline; Humans; Labor Stage, First; Labor, Obstetric; Obstetric Labor, Prematu

1978
[The significance of prostaglandin F2 alpha (PGFM)--and plasma oxytocin level in patients with premature labor].
    Geburtshilfe und Frauenheilkunde, 1992, Volume: 52, Issue:8

    Topics: Birth Weight; Dinoprost; Female; Gestational Age; Hexoprenaline; Humans; Infant, Newborn; Infusions,

1992
Pulmonary oedema after hexoprenaline administration in preterm labour. A report of 4 cases.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1991, May-18, Volume: 79, Issue:10

    Topics: Adult; Female; Hexoprenaline; Humans; Obstetric Labor, Premature; Pregnancy; Pulmonary Edema

1991
Introduction of hexoprenaline into the treatment of preterm labor.
    American journal of obstetrics and gynecology, 1989, Volume: 161, Issue:4

    Topics: Female; Hexoprenaline; Humans; In Vitro Techniques; Obstetric Labor, Premature; Phenethylamines; Pre

1989
[Hexoprenaline--a new tocolytic for treatment of premature labor].
    Arzneimittel-Forschung, 1985, Volume: 35, Issue:5

    Topics: Female; Fenoterol; Hemodynamics; Hexoprenaline; Humans; Obstetric Labor, Premature; Phenethylamines;

1985
[Usefulness of the addition of aspartate magnesium hydrochloride via intravenous route to beta mimetics in the treatment of threatened premature labor].
    Revue medicale de la Suisse romande, 1988, Volume: 108, Issue:4

    Topics: Adult; Aspartic Acid; Drug Evaluation; Drug Therapy, Combination; Female; Hexoprenaline; Humans; Mag

1988
[10 years of tocolysis at the Linz Gynecologic Clinic].
    Gynakologische Rundschau, 1988, Volume: 28, Issue:2

    Topics: Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Hexoprenaline; Humans; Infus

1988
[Heart function in infants and small children, whose mothers required tocolysis with hexoprenaline sulfate (Gynipral)].
    Wiener klinische Wochenschrift, 1986, Sep-26, Volume: 98, Issue:18

    Topics: Child, Preschool; Echocardiography; Electrocardiography; Female; Heart Rate; Hemodynamics; Hexoprena

1986