hexobarbital has been researched along with Uremia in 3 studies
Hexobarbital: A barbiturate that is effective as a hypnotic and sedative.
hexobarbital : A member of the class of barbiturates taht is barbituric acid substituted at N-1 by methyl and at C-5 by methyl and cyclohex-1-enyl groups.
Uremia: A clinical syndrome associated with the retention of renal waste products or uremic toxins in the blood. It is usually the result of RENAL INSUFFICIENCY. Most uremic toxins are end products of protein or nitrogen CATABOLISM, such as UREA or CREATININE. Severe uremia can lead to multiple organ dysfunctions with a constellation of symptoms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Urea pretreatment slows hexobarbital metabolsim and prolongs hexobarbital sleep times." | 1.26 | Effects of urea on hexobarbital and antipyrine disposition in rats. ( Bachmann, K; Valentovic, M, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Valentovic, M | 1 |
| Bachmann, K | 1 |
| Leber, HW | 1 |
| Uviss, T | 1 |
| Prenter, A | 1 |
| Terner, UK | 1 |
| Wiebe, LI | 1 |
| Noujaim, AA | 1 |
| Dssetor, JB | 1 |
| Sanders, EJ | 1 |
3 other studies available for hexobarbital and Uremia
| Article | Year |
|---|---|
Effects of urea on hexobarbital and antipyrine disposition in rats.
Topics: Animals; Antipyrine; Blood Urea Nitrogen; Cytochrome P-450 Enzyme System; Drug Interactions; Female; | 1980 |
Influence of the plasticiser di-2-ethylhexyl-phthalate on drug metabolising enzymes in the liver of uraemic rats.
Topics: Animals; Diethylhexyl Phthalate; Dose-Response Relationship, Drug; Esterases; Hexobarbital; Liver; M | 1979 |
The effects of acute and chronic uremia in rats on their hepatic microsomal enzyme activity.
Topics: Acute Disease; Adrenal Cortex Hormones; Alcohol Oxidoreductases; Aminopyrine N-Demethylase; Animals; | 1978 |