hexobarbital has been researched along with Palsy in 40 studies
Hexobarbital: A barbiturate that is effective as a hypnotic and sedative.
hexobarbital : A member of the class of barbiturates taht is barbituric acid substituted at N-1 by methyl and at C-5 by methyl and cyclohex-1-enyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Effects of furazolidone (FZ) on the sleeping time induced with hexobarbital (HEX) and paralysis time induced by zoxazolamine (ZOX) were investigated by measuring the length of time required to recover from righting reflex loss in rats after oral administration of FZ at doses of 50, 100, 200 and 400 mg/kg/day for 4 successive days." | 3.69 | Effects of furazolidone on duration of righting reflex loss induced with hexobarbital and zoxazolamine in the rat. ( Sasaki, N, 1994) |
| "In male rats bearing carrageenan-induced paw edema twenty-four hours after treatment with carrageenan the duration of hexobarbital hypnosis was prolonged and the rate of hepatic hexobarbital metabolism was inhibited." | 3.68 | Modulation of zoxazolamine metabolism in carrageenan-induced inflammation in rats. ( Ishikawa, M; Sasaki, K; Yakayanagi, Y, 1990) |
| "Using hexobarbital sleeping and zoxazolamine paralysis time as indices of in vivo hepatic drug metabolism, the effects of endotoxin on drug action appear to be time- and dose-dependent and the lipid A moiety of endotoxin appears to be responsible for its inhibitory effects." | 3.67 | Effects of lipid A content, hydrocortisone and polymyxin B on endotoxin-induced decreases in in vivo drug metabolism. ( Abernathy, CO; Utili, R; Zimmerman, HJ, 1987) |
| " dose (5 mg/kg) of a light lanthanon, praseodymium, prolonged the duration of hexobarbital-induced sleep and zoxazolamine-induced paralysis, as well as it modified pharmacokinetic parameters of hexobarbital and zoxazolamine, in rats." | 3.67 | Effect of praseodymium chloride on liver microsomal enzymes of rats. ( Araujo Filho, AP; Galvão, JF; Oga, S; Yasaka, WJ, 1986) |
| " Pretreatment with piperine prolonged hexobarbital sleeping time and zoxazolamine paralysis time in mice at half the dose of SKF-525A." | 3.67 | Biochemical basis of enhanced drug bioavailability by piperine: evidence that piperine is a potent inhibitor of drug metabolism. ( Atal, CK; Dubey, RK; Singh, J, 1985) |
| " Both agents also prolonged hexobarbital sleeping time and zoxazolamine paralysis time in mice." | 3.66 | Protective effect of diethyldithiocarbamate and carbon disulfide against liver injury induced by various hepatotoxic agents. ( Masuda, Y; Nakayama, N, 1982) |
| "A single 8-h exposure to trans-1,2-dichloroethylene (t-DCE) or cis-1,2-dichloroethylene (c-DCE) at 200 ppm (hygienic standard in workplaces) resulted in a significant increase in the hexobarbital sleeping time, the zoxazolamine paralysis time, and the metabolic formation of 4-aminoantipyrine from aminopyrine in adult female Wistar rats." | 3.66 | Inhibition of mixed function oxidases in rat liver by trans- and cis-1,2-dichloroethylene. ( Freundt, KJ; Macholz, J, 1978) |
| "Zoxazolamine paralysis, hexobarbital anesthesia and digitoxin convulsions were diminished in rats by 3 days of pretreatment with pregnenolone-16alpha-carbonitrile (PCN)." | 3.65 | Studies on drug metabolism and liver ultrastructure after conjoint treatment with pregnenolone-16alpha-carbonitrile and dl-ethionine. ( Garg, BD; Kourounakis, P; Kovacs, K; Szabo, S; Tuchweber, B, 1977) |
| "Sixteen strains of mice were compared with respect to their hexobarbitone sleeping time and their zoxazolamine paralysis time." | 3.65 | A survey of the response of different strains of mice to substances metabolised by microsomal oxidation; hexobarbitone, zoxazolamine and warfarin. ( Lush, IE, 1976) |
| " A single oral 24-hr pretreatment with CVP (15 mg/kg) increased the oral LD50 of its next dosage to threefold." | 1.28 | Metabolic induction of the hepatic cytochrome P450 system by chlorfenvinphos in rats. ( Ikeda, T; Shirasu, Y; Tsuda, S, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 36 (90.00) | 18.7374 |
| 1990's | 3 (7.50) | 18.2507 |
| 2000's | 1 (2.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| PERRET, W | 1 |
| VON REDWITZ, E | 1 |
| Singh, B | 1 |
| Chandan, BK | 1 |
| Sharma, N | 1 |
| Bhardwaj, V | 1 |
| Satti, NK | 1 |
| Gupta, VN | 1 |
| Gupta, BD | 1 |
| Suri, KA | 1 |
| Suri, OP | 1 |
| Calley, DJ | 1 |
| Guess, WL | 1 |
| Autian, J | 1 |
| Cram, RL | 1 |
| Fouts, JR | 1 |
| Masuda, Y | 1 |
| Nakayama, N | 1 |
| Graham, JA | 1 |
| Menzel, DB | 1 |
| Miller, FJ | 1 |
| Illing, JW | 1 |
| Gardner, DE | 1 |
| Abernathy, CO | 3 |
| Zimmerman, HJ | 2 |
| Utili, R | 2 |
| Sasaki, N | 1 |
| Freundt, KJ | 1 |
| Macholz, J | 1 |
| Yasaka, WJ | 2 |
| Sasame, HA | 1 |
| Saul, W | 1 |
| Maling, HM | 1 |
| Gillette, JR | 1 |
| Unseld, A | 1 |
| de Matteis, F | 1 |
| Garg, BD | 2 |
| Kourounakis, P | 1 |
| Tuchweber, B | 3 |
| Szabo, S | 2 |
| Kovacs, K | 3 |
| Mathur, PP | 1 |
| Smyth, RD | 1 |
| Witmer, CM | 1 |
| Carr, GS | 1 |
| Reavey-Cantwell, NH | 1 |
| Wiebel, FJ | 1 |
| Waters, HL | 1 |
| Elliot, S | 1 |
| Gelboin, HV | 1 |
| Lush, IE | 1 |
| Ikeda, T | 1 |
| Tsuda, S | 1 |
| Shirasu, Y | 1 |
| Ishikawa, M | 1 |
| Sasaki, K | 2 |
| Yakayanagi, Y | 1 |
| Oga, S | 1 |
| Galvão, JF | 1 |
| Araujo Filho, AP | 1 |
| Atal, CK | 1 |
| Dubey, RK | 1 |
| Singh, J | 1 |
| Buchel, L | 1 |
| Absil, J | 1 |
| Murawsky, M | 1 |
| Kato, R | 3 |
| Takanaka, A | 3 |
| Coper, H | 1 |
| von Herrath, D | 1 |
| Veit, J | 1 |
| Grosse, W | 1 |
| Wade, AE | 1 |
| Stonard, MD | 1 |
| Nenov, PZ | 1 |
| Lazar, G | 1 |
| Murphy, JP | 1 |
| Van Stee, EW | 1 |
| Back, KC | 1 |
| Radzialowski, FM | 1 |
| Oppermann, JA | 1 |
| Khandekar, JD | 1 |
| Dardachti, D | 1 |
| Brodeur, J | 1 |
| Marchand, C | 1 |
| Stull, RE | 1 |
| Ferguson, NM | 1 |
| Ferguson, GG | 1 |
| Prabhu, VG | 1 |
| Oester, YT | 1 |
| Philpot, RM | 1 |
| Guthrie, FE | 1 |
| Hodgson, E | 1 |
| Onoda, K | 1 |
| Fujii, K | 1 |
| Jaffe, H | 1 |
| Bishop, Y | 1 |
| Arnold, E | 1 |
| Mackintosh, D | 1 |
| Epstein, SS | 1 |
| Lemberger, L | 1 |
| Sernatinger, E | 1 |
| Kuntzman, R | 1 |
| Gerber, N | 1 |
| Arnold, K | 1 |
| Dewhurst, F | 1 |
| Kitchen, DA | 1 |
40 other studies available for hexobarbital and Palsy
| Article | Year |
|---|---|
[Evipan and curare paralysis as special form of narcosis paralysis].
Topics: Barbital; Curare; Hexobarbital; Paralysis; Stupor | 1951 |
[Evipan and curare paralysis as a special form of anesthetic paralysis].
Topics: Anesthesia; Anesthetics; Brachial Plexus; Curare; Hexobarbital; Humans; Paralysis | 1951 |
Isolation, structure elucidation and in vivo hepatoprotective potential of trans-tetracos-15-enoic acid from Indigofera tinctoria Linn.
Topics: Acetaminophen; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Fatty Acids, M | 2006 |
Hepatotoxicity of a series of organotin esters.
Topics: Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Ataxia; Behavior, Animal; Blepharoptosis | 1967 |
The influence of DDT and gamma-chlordane on the metabolism of hexobarbital and zoxazolamine in 2 mouse strains.
Topics: Animals; Chlordan; DDT; Hexobarbital; Male; Mice; Paralysis; Sleep; Zoxazolamine | 1967 |
Protective effect of diethyldithiocarbamate and carbon disulfide against liver injury induced by various hepatotoxic agents.
Topics: Animals; Carbon Disulfide; Chemical and Drug Induced Liver Injury; Ditiocarb; Hexobarbital; Male; Mi | 1982 |
Effect of ozone on drug-induced sleeping time in mice pretreated with mixed-function oxidase inducers and inhibitors.
Topics: Animals; Drug Interactions; Enzyme Induction; Female; Hexobarbital; Mice; Mice, Inbred C57BL; Mice, | 1982 |
Effects of endotoxin-tolerance on in vivo drug metabolism in mice.
Topics: Animals; Drug Interactions; Drug Tolerance; Endotoxins; Hexobarbital; Male; Mice; Mice, Inbred BALB | 1980 |
Effects of furazolidone on duration of righting reflex loss induced with hexobarbital and zoxazolamine in the rat.
Topics: Administration, Oral; Animals; Body Weight; Cytochrome P-450 Enzyme System; Dose-Response Relationsh | 1994 |
Inhibition of mixed function oxidases in rat liver by trans- and cis-1,2-dichloroethylene.
Topics: Animals; Dichloroethylenes; Female; Hexobarbital; Hydrocarbons, Chlorinated; In Vitro Techniques; Ki | 1978 |
Mechanisms in the potentiation and inhibition of pharmacological actions of hexobarbital and zoxazolamine by glycofurol.
Topics: Animals; Behavior, Animal; Brain; Drug Interactions; Furans; Hexobarbital; In Vitro Techniques; Kine | 1978 |
Destruction of endogenous and exogenous haem by 2-allyl-2-isopropylacetamide: role of the liver cytochrome P-450 which is inducible by phenobarbitone.
Topics: Acetamides; Allylisopropylacetamide; Aminolevulinic Acid; Animals; Cytochrome P-450 Enzyme System; E | 1978 |
Studies on drug metabolism and liver ultrastructure after conjoint treatment with pregnenolone-16alpha-carbonitrile and dl-ethionine.
Topics: Animals; Digitoxin; Drug Interactions; Ethionine; Female; Hexobarbital; In Vitro Techniques; Liver; | 1977 |
Temporal pattern and reversal of impaired hepatic mono-oxygenases by phenobarbital in rats with developing and established adjuvant disease.
Topics: Animals; Arthritis; Arthritis, Experimental; Cytochromes; Hexobarbital; Male; Microsomes, Liver; Oxy | 1977 |
Effect of 7 8-benzoflavone on the duration of zoxazolamine paralysis and hexobarbital hypnosis in rats.
Topics: Animals; Depression, Chemical; Flavonoids; Hexobarbital; Male; Methylcholanthrene; Paralysis; Phenob | 1976 |
A survey of the response of different strains of mice to substances metabolised by microsomal oxidation; hexobarbitone, zoxazolamine and warfarin.
Topics: Animals; Female; Hexobarbital; Male; Mice; Mice, Inbred Strains; Microsomes, Liver; Paralysis; Sex F | 1976 |
Metabolic induction of the hepatic cytochrome P450 system by chlorfenvinphos in rats.
Topics: Animals; Chlorfenvinphos; Cytochrome P-450 Enzyme System; Cytochromes b5; Enzyme Induction; Hexobarb | 1991 |
Modulation of zoxazolamine metabolism in carrageenan-induced inflammation in rats.
Topics: Animals; Carrageenan; Edema; Female; Foot; Hexobarbital; Male; Paralysis; Rats; Rats, Inbred Strains | 1990 |
Effects of lipid A content, hydrocortisone and polymyxin B on endotoxin-induced decreases in in vivo drug metabolism.
Topics: Animals; Endotoxins; Escherichia coli; Female; Hexobarbital; Hydrocortisone; Lipid A; Liver; Mice; M | 1987 |
Effect of praseodymium chloride on liver microsomal enzymes of rats.
Topics: Animals; Cytochrome b Group; Cytochrome P-450 Enzyme System; Cytochromes b5; Drug Synergism; Half-Li | 1986 |
Biochemical basis of enhanced drug bioavailability by piperine: evidence that piperine is a potent inhibitor of drug metabolism.
Topics: Alkaloids; Animals; Aryl Hydrocarbon Hydroxylases; Benzodioxoles; Biological Availability; Dose-Resp | 1985 |
[Half-life of hexobarbital and zoxazolamine in rodents. 2-In the rat].
Topics: Animals; Brain Chemistry; Female; Half-Life; Hexobarbital; Injections, Intravenous; Male; Paralysis; | 1974 |
Effect of starvation on the in vivo metabolism and effect of drugs in female and male rats.
Topics: Amides; Anesthesia; Animals; Barbiturates; Body Weight; Carisoprodol; Diphosphates; Female; Hexobarb | 1967 |
On the mechanism of the sleep-prolonging effect of antimetabolites of nicotinamide.
Topics: Anesthesia; Animals; Antimetabolites; Brain; Central Nervous System; Glucosephosphate Dehydrogenase; | 1968 |
The effect of thiamine consumption on liver microsomal drug-metabolizing pathways.
Topics: Aminopyrine; Aniline Compounds; Animals; Body Weight; Cytochromes; Diet; Esterases; Female; Glucosep | 1971 |
Effect of hexachlorobenzene on hepatic microsomal enzymes in the rat.
Topics: Aging; Alcohol Oxidoreductases; Animals; Chlorobenzenes; Cytochrome P-450 Enzyme System; Diet; Enzym | 1974 |
Effect of hypophysectomy and cyproterone acetate on the liver ultrastructure as well as on hexobarbital anesthesia and zoxazolamine paralysis in rats.
Topics: Androgen Antagonists; Animals; Body Weight; Cyproterone; Enzyme Induction; Female; Hexobarbital; Hyp | 1973 |
Effect of dibromotetrafluoroethane inhalation on hepatic drug metabolism in mice.
Topics: Animals; Chlorofluorocarbons, Methane; Drug Interactions; Hexobarbital; Hydrocarbons, Halogenated; L | 1973 |
Effect of phencyclidine on hepatic drug metabolism in the rat.
Topics: Aminopyrine; Animals; Anisoles; Dealkylation; Hexobarbital; Hydroxylation; Liver; Male; Nitro Compou | 1974 |
Hepatic fine structural changes and microsomal hypofunction in Walker tumor-bearing rats.
Topics: Adenocarcinoma; Animals; Benz(a)Anthracenes; Carcinoma 256, Walker; Endoplasmic Reticulum; Female; H | 1972 |
Effect of splenectomy on the activity of drug-metabolizing enzymes in the liver of rats.
Topics: Animals; Anisoles; Biological Assay; Carbon Isotopes; Cytochromes; Enzyme Induction; Female; Hexobar | 1971 |
Selected pharmacological studies of an alkaloidal extract of Banisteriopsis quitensis.
Topics: Alkaloids; Animals; Ataxia; Blood Pressure; Drug Interactions; Electrocardiography; Hallucinogens; H | 1971 |
Neuromuscular functions of mature mice following neonatal monosodium glutamate.
Topics: Animals; Animals, Newborn; Body Weight; Crowding; Dextroamphetamine; Female; Food Additives; Glutama | 1971 |
Inductive effects of 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane(DDT), phenobarbital, and benzpyrene on microsomal cytochrome B450, ethyl isocyanide spectra, and metabolism in vivo of zoxazolamine and hexobarbital in the mouse.
Topics: Animals; Benzopyrenes; Cyanides; Cytochrome P-450 Enzyme System; DDT; Enzyme Induction; Hexobarbital | 1971 |
Metabolism of drugs in old rats. II. Metabolism in vivo and effect of drugs in old rats.
Topics: Aging; Anesthesia; Animals; Carisoprodol; Female; Hexobarbital; Injections, Intraperitoneal; Insecti | 1968 |
Studies on age difference in mice for the activity of drug-metabolizing enzymes of liver microsomes.
Topics: Aging; Aminopyrine; Anesthesia; Aniline Compounds; Animals; Body Weight; Cytochromes; Electron Trans | 1970 |
Structure-activity relations for methylenedioxyphenyl and related compounds on hepatic microsomal enzyme function, as measured by prolongation of hexobarbital narcosis and zoxazolamine paralysis in mice.
Topics: Chemical Phenomena; Chemistry; Dioxoles; Drug Synergism; Hexobarbital; Insecticides; Microsomes, Liv | 1970 |
Effect of desmethylimipramine, iprindole and DL-erythro-alpha-(3,4-dichlorophenyl)-beta-(t-butyl amino) propanol HC1 on the metabolism of amphetamine.
Topics: 1-Propanol; Amines; Amino Alcohols; Amphetamine; Animals; Antidepressive Agents; Brain; Butylamines; | 1970 |
Studies on the metabolism of diphenylhydantoin in mice.
Topics: Animals; Cycloheximide; Cytochromes; Hexobarbital; Hydroxyzine; Kinetics; Liver; Male; Mice; Microso | 1969 |
The effect of benzo[a]pyrene derivatives upon drug metabolising enzyme activities.
Topics: Animals; Benzopyrenes; Chemical Phenomena; Chemistry; Enzyme Induction; Hexobarbital; Liver; Mice; P | 1969 |