hexobarbital has been researched along with Jaundice in 4 studies
Hexobarbital: A barbiturate that is effective as a hypnotic and sedative.
hexobarbital : A member of the class of barbiturates taht is barbituric acid substituted at N-1 by methyl and at C-5 by methyl and cyclohex-1-enyl groups.
Jaundice: A clinical manifestation of HYPERBILIRUBINEMIA, characterized by the yellowish staining of the SKIN; MUCOUS MEMBRANE; and SCLERA. Clinical jaundice usually is a sign of LIVER dysfunction.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In experiment 1 no serial changes were seen in activities of hexobarbital hydroxylase or benzo(a)pyrene hydroxylase in hepatic microsomes isolated after 2, 4 or 7 days from homozygous jaundiced female Gunn rats exposed to continuous phototherapy or in matched Gunn rats maintained under dim light." | 7.67 | Effects of phototherapy on the activity of microsomal mixed-function monooxygenases and the pharmacokinetics of [14C] hexobarbital in jaundiced and heterozygous Gunn rats. ( Kapitulnik, J; Ostrow, JD; Tabata, M; Webster, CC; Zucker, GM, 1986) |
| " In experiment 1 no serial changes were seen in activities of hexobarbital hydroxylase or benzo(a)pyrene hydroxylase in hepatic microsomes isolated after 2, 4 or 7 days from homozygous jaundiced female Gunn rats exposed to continuous phototherapy or in matched Gunn rats maintained under dim light." | 3.67 | Effects of phototherapy on the activity of microsomal mixed-function monooxygenases and the pharmacokinetics of [14C] hexobarbital in jaundiced and heterozygous Gunn rats. ( Kapitulnik, J; Ostrow, JD; Tabata, M; Webster, CC; Zucker, GM, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| FOUTS, JR | 1 |
| Calley, DJ | 1 |
| Guess, WL | 1 |
| Autian, J | 1 |
| Tabata, M | 1 |
| Ostrow, JD | 1 |
| Webster, CC | 1 |
| Zucker, GM | 1 |
| Kapitulnik, J | 1 |
| Franken, FH | 1 |
| Hagelskamp, W | 1 |
4 other studies available for hexobarbital and Jaundice
| Article | Year |
|---|---|
FACTORS AFFECTING HEPATIC MICROSOMAL ENZYME SYSTEMS INVOLVED IN DRUG METABOLISM.
Topics: Alloxan; Aminopyrine; Carcinoma, Hepatocellular; Chlordan; Chlorpromazine; Codeine; Hexobarbital; Ja | 1963 |
Hepatotoxicity of a series of organotin esters.
Topics: Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Ataxia; Behavior, Animal; Blepharoptosis | 1967 |
Effects of phototherapy on the activity of microsomal mixed-function monooxygenases and the pharmacokinetics of [14C] hexobarbital in jaundiced and heterozygous Gunn rats.
Topics: Animals; Bilirubin; Carbon Radioisotopes; Female; Hematocrit; Heterozygote; Hexobarbital; Homozygote | 1986 |
[Barbiturates and liver].
Topics: Amobarbital; Animals; Barbiturates; Chemical and Drug Induced Liver Injury; Enzyme Activation; Fatty | 1970 |