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hexobarbital and Innate Inflammatory Response

hexobarbital has been researched along with Innate Inflammatory Response in 10 studies

Hexobarbital: A barbiturate that is effective as a hypnotic and sedative.
hexobarbital : A member of the class of barbiturates taht is barbituric acid substituted at N-1 by methyl and at C-5 by methyl and cyclohex-1-enyl groups.

Research Excerpts

ExcerptRelevanceReference
"Treatment of male rats with phenobarbital markedly stimulated, the activity of the hepatic microsomal monooxygenase system while in rats bearing carrageenan-induced inflammation the activity of this system was lowered."7.68The effect of phenobarbital on the impairment of drug metabolism by carrageenan-induced inflammation in male rat. ( Ishikawa, M; Sasaki, K; Takayanagi, Y, 1990)
"Treatment of male rats with phenobarbital markedly stimulated, the activity of the hepatic microsomal monooxygenase system while in rats bearing carrageenan-induced inflammation the activity of this system was lowered."3.68The effect of phenobarbital on the impairment of drug metabolism by carrageenan-induced inflammation in male rat. ( Ishikawa, M; Sasaki, K; Takayanagi, Y, 1990)
"Hexobarbital hypnosis was significantly prolonged by carrageenan treatment in intact and testectomized animals as compared to their respective controls."1.28Inhibition of hepatic drug biotransformation by carrageenan-induced inflammation in the rat: effect of sex hormone alterations. ( Ishikawa, M; Ozaki, M; Sasaki, K; Takayanagi, Y, 1992)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19906 (60.00)18.7374
1990's3 (30.00)18.2507
2000's0 (0.00)29.6817
2010's1 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Saunders, MJ1
Edwards, BS1
Zhu, J1
Sklar, LA1
Graves, SW1
Ishikawa, M4
Sasaki, K8
Ozaki, M3
Takayanagi, Y4
Watanabe, K1
Whitehouse, MW3
Beck, FJ1
Baumgartner, WA1
Beck, FW1
Lorber, A1
Pearson, CM1
Prabhu, VG1
Rise, NL1
Oester, YT1
Jahn, U1
Adrian, RW1

Other Studies

10 other studies available for hexobarbital and Innate Inflammatory Response

ArticleYear
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
    Current protocols in cytometry, 2010, Volume: Chapter 13

    Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr

2010
Inhibition of hepatic drug biotransformation by carrageenan-induced inflammation in the rat: effect of sex hormone alterations.
    Journal of pharmacobio-dynamics, 1992, Volume: 15, Issue:8

    Topics: Aminopyrine; Animals; Biotransformation; Carrageenan; Cytochrome P-450 Enzyme System; Estradiol; Eth

1992
Hepatic drug metabolizing activity in rats with carrageenan-induced inflammation.
    Journal of pharmacobio-dynamics, 1991, Volume: 14, Issue:3

    Topics: Animals; Carrageenan; Cytochrome P-450 Enzyme System; Cytochromes b5; Female; Hexobarbital; Inflamma

1991
The effect of phenobarbital on the impairment of drug metabolism by carrageenan-induced inflammation in male rat.
    Research communications in chemical pathology and pharmacology, 1990, Volume: 69, Issue:3

    Topics: Animals; Carrageenan; Cytochrome P-450 Enzyme System; Hexobarbital; Inflammation; Male; Microsomes,

1990
Sex-related alteration of drug action in carrageenan-induced inflammation in the rat.
    Research communications in chemical pathology and pharmacology, 1989, Volume: 65, Issue:2

    Topics: Animals; Carrageenan; Female; Hexobarbital; Inflammation; Male; Mixed Function Oxygenases; Rats; Rat

1989
Abnormal drug metabolism in rats after an inflammatory insult.
    Agents and actions, 1973, Volume: 3, Issue:5

    Topics: Adjuvants, Immunologic; Aminopyrine; Animals; Carrageenan; Corynebacterium; Cyclophosphamide; Hexoba

1973
Impaired drug metabolism in rats associated with acute inflammation: a possible assay for anti-injury agents.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1974, Volume: 145, Issue:1

    Topics: Aminopyrine; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Azathioprine; Biological Assa

1974
Adjuvant disease in rats: biochemical criteria for distinguishing several phases of inflammation and arthritis.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1974, Volume: 145, Issue:2

    Topics: Adjuvants, Immunologic; Albuminuria; Animals; Arthritis; Blood Proteins; Ear, External; Foot; Hexoba

1974
The effect of experimental local inflammation on the action of barbiturates in rat.
    Archives internationales de pharmacodynamie et de therapie, 1972, Volume: 195, Issue:2

    Topics: Animals; Barbiturates; Carbon Tetrachloride; Carrageenan; Charcoal; Chlordan; Enzyme Induction; Goss

1972
[Pharmacological and toxicological testing of new anti-inflammatory agent azapropazon=3-dimethylamine-7-methyl-1,2-(n-propylmalonyl)-1,2-dihydro-1,2,4-benzotriazine].
    Arzneimittel-Forschung, 1969, Volume: 19, Issue:1

    Topics: Abnormalities, Drug-Induced; Analgesics; Anesthetics, Local; Animals; Anti-Inflammatory Agents; Bloo

1969