Compounds > hexobarbital
Page last updated: 2024-10-28

hexobarbital and Drug Withdrawal Symptoms

hexobarbital has been researched along with Drug Withdrawal Symptoms in 13 studies

Hexobarbital: A barbiturate that is effective as a hypnotic and sedative.
hexobarbital : A member of the class of barbiturates taht is barbituric acid substituted at N-1 by methyl and at C-5 by methyl and cyclohex-1-enyl groups.

Research Excerpts

ExcerptRelevanceReference
"The barbital treatment induced a clear tolerance to the hexobarbital, which still could be detected on day 28 of abstinence."1.26The effects of atropine on the tolerance and the convulsions seen after withdrawal from forced barbital drinking in the rat. ( Wahlström, G, 1978)
" The average weekly dosage was around 215 mg/kg in groups 1, 3 and 5."1.26Studies on acute tolerance to ethanol in the abstinence period after long-term barbital treatment in the rat. ( Wahlström, G, 1979)
"The effect of electrically induced convulsions was tested on the tolerance to hexobarbital after chronic barbital treatment in male rats."1.26The interaction between electrically induced convulsions and tolerance in the abstinence period after chronic barbital treatments in the rat. ( Wahlström, G, 1976)
"Mice were given several atropine injections at a high dosage level."1.25Sensitivity changes to morphine and other drugs induced by cholinergic blockade. ( Contreras, E; Quijada, L; Tamayo, L, 1975)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-199011 (84.62)18.7374
1990's2 (15.38)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kaneto, H1
Kosaka, N1
Takasu, M1
Mino, T1
Wahlström, G9
Korkmaz, S2
Carlsson, S1
Contreras, E1
Tamayo, L1
Quijada, L1
Stevenson, IH2
Turnbull, MJ2

Other Studies

13 other studies available for hexobarbital and Drug Withdrawal Symptoms

ArticleYear
[Studies on the physical dependence liability to guanabenz].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1982, Volume: 80, Issue:5

    Topics: Analgesics; Animals; Antihypertensive Agents; Barbital; Body Weight; Drug Synergism; Guanabenz; Guan

1982
Atropine in the abstinence after chronic barbital treatment in the rat.
    Pharmacology, biochemistry, and behavior, 1980, Volume: 13 Suppl 1

    Topics: Animals; Atropine; Barbital; Barbiturates; Dose-Response Relationship, Drug; Drug Tolerance; Hexobar

1980
Maturation-related changes in tolerance development to hexobarbital after short term treatment with diazepam in the rat.
    Brain research, 1993, Jan-15, Volume: 600, Issue:2

    Topics: Aging; Animals; Diazepam; Drug Tolerance; Electroencephalography; Hexobarbital; Male; Rats; Rats, Sp

1993
Physical dependence after benzodiazepine treatments in rats: Comparison of short and long treatments with diazepam and lorazepam.
    Journal of studies on alcohol, 1999, Volume: 60, Issue:4

    Topics: Animals; Anti-Anxiety Agents; Arousal; Brain; Diazepam; Dose-Response Relationship, Drug; Drug Admin

1999
The effects of atropine on the tolerance and the convulsions seen after withdrawal from forced barbital drinking in the rat.
    Psychopharmacology, 1978, Oct-31, Volume: 59, Issue:2

    Topics: Animals; Atropine; Barbital; Barbiturates; Drug Tolerance; Electroencephalography; Hexobarbital; Hum

1978
Studies on acute tolerance to ethanol in the abstinence period after long-term barbital treatment in the rat.
    Acta pharmacologica et toxicologica, 1979, Volume: 45, Issue:2

    Topics: Animals; Barbital; Barbiturates; Brain; Drug Tolerance; Ethanol; Hexobarbital; Humans; Male; Rats; S

1979
The interaction between electrically induced convulsions and tolerance in the abstinence period after chronic barbital treatments in the rat.
    Psychopharmacology, 1976, Aug-17, Volume: 48, Issue:3

    Topics: Animals; Barbital; Barbiturates; Drug Tolerance; Electroshock; Hexobarbital; Humans; Male; Rats; Sei

1976
The interaction between spontaneous convulsions and tolerance to hexobarbital in the abstinence after chronic barbital treatments in the rat.
    Life sciences, 1976, Dec-15, Volume: 19, Issue:12

    Topics: Animals; Barbital; Barbiturates; Drug Tolerance; Hexobarbital; Humans; Male; Rats; Seizures; Substan

1976
Sensitivity changes to morphine and other drugs induced by cholinergic blockade.
    Archives internationales de pharmacodynamie et de therapie, 1975, Volume: 214, Issue:2

    Topics: Amphetamine; Analgesics; Animals; Arecoline; Atropine; Drug Tolerance; Female; Hexobarbital; Humans;

1975
Withdrawal in the rat after long-term forced oral barbital administration.
    Acta pharmacologica et toxicologica, 1974, Volume: 35, Issue:2

    Topics: Administration, Oral; Animals; Body Weight; Depression, Chemical; Drinking Behavior; Drug Tolerance;

1974
Changes in a hexobarbital anaesthesia threshold in rats induced by repeated long-term treatment with barbital or ethanol.
    Psychopharmacologia, 1971, Volume: 19, Issue:4

    Topics: Anesthesia; Animals; Barbiturates; Drug Synergism; Drug Tolerance; Electroencephalography; Ethanol;

1971
Hexobarbitone response in barbitone-dependent and withdrawn rats.
    British journal of pharmacology, 1968, Volume: 34, Issue:1

    Topics: Anesthesia; Animals; Brain Chemistry; Drug Hypersensitivity; Drug Tolerance; Female; Hexobarbital; H

1968
Hepatic drug-metabolising enzyme activity and duration of hexobarbitone anaesthesia in barbitone-dependent and withdrawn rats.
    Biochemical pharmacology, 1968, Volume: 17, Issue:11

    Topics: Anesthesia; Animals; Barbiturates; Body Weight; Drug Tolerance; Female; Hexobarbital; Humans; Liver;

1968