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hexobarbital and Carbon Tetrachloride Poisoning

hexobarbital has been researched along with Carbon Tetrachloride Poisoning in 43 studies

Hexobarbital: A barbiturate that is effective as a hypnotic and sedative.
hexobarbital : A member of the class of barbiturates taht is barbituric acid substituted at N-1 by methyl and at C-5 by methyl and cyclohex-1-enyl groups.

Carbon Tetrachloride Poisoning: Poisoning that results from ingestion, injection, inhalation, or skin absorption of CARBON TETRACHLORIDE.

Research Excerpts

ExcerptRelevanceReference
" The beta receptor blocking propranolol prevented functional lesion, moderated fatty degeneration and liver cell necrosis in chronic carbon tetrachloride injury."3.66Estrogens as disposing factors in experimental liver injury. ( Gomba, S; Kulcsár, A; Kulscár-Gergely, J, 1978)
"When thioacetamide was given for a prolonged period, the ascorbic acid content in the urine increased at the beginning; later one, at the end of three weeks, it was slightly inferior to the control value."1.26[The excretion of hippuric acid and ascorbic acid in the urine of liver-damaged rats (author's transl]. ( Bien, E; Kündiger, R; Müller, R; Skorka, G, 1979)

Research

Studies (43)

TimeframeStudies, this research(%)All Research%
pre-199040 (93.02)18.7374
1990's2 (4.65)18.2507
2000's0 (0.00)29.6817
2010's1 (2.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sharma, N1
Shukla, S1
Schade, R1
Rex, H1
Kästner, D1
Sprang, C1
Jacob, V1
Chang, IM1
Ryu, JC1
Park, YC1
Yun, HS1
Yang, KH1
Bien, E3
Skorka, G2
Kündiger, R2
Müller, R2
Ugazio, G6
Danni, O1
Milillo, P1
Burdino, E3
Congiu, AM1
Bosia, S1
Cornaglia, E1
Anand, KK1
Singh, B1
Saxena, AK1
Chandan, BK1
Gupta, VN1
Bhardwaj, V1
Benakis, A1
Corthay, J1
Medilanski, P1
Dormard, Y1
Lévy, JC1
Suriyachan, D1
Thithapandha, A1
Schmidt, P1
Wolff, DL1
Burck, D1
Wilhelm, M1
Kulcsár, A6
Kulcsár-Gergely, J4
Udvardy, M1
Dolci, ED1
Brabec, MJ1
Kulscár-Gergely, J1
Gomba, S1
Gans, JH1
Schröder, S1
Kuhlmey, B1
Kiss, A1
Torrielli, MV3
Gergely, J1
Brenner, G1
Trautmann, H1
Heni, N2
Remmer, H1
Tuchweber, B1
Werringloer, J1
Kourounakis, P1
Gabriel, L2
Janiak, B1
Kessler, B1
Kunz, W1
Schnieders, B1
Mancini, RE1
Kocsis, JJ1
Koch, RR1
Recknagel, RO1
Reiner, O1
Uehleke, H1
Wei, E1
Wong, LC1
Hine, CH1
Vorne, M2
Lange, P1
Jung, F1
Varga, F1
Fischer, E1
Srinivasan, S2
Balwani, JH2
Lal, H1
Puri, SK1
Fuller, GC1
Klinger, W2
Stenger, RJ1
Johnson, EA1
Dingell, JV1
Heimberg, M1

Other Studies

43 other studies available for hexobarbital and Carbon Tetrachloride Poisoning

ArticleYear
Hepatoprotective potential of aqueous extract of Butea monosperma against CCl(4) induced damage in rats.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2011, Volume: 63, Issue:7-8

    Topics: Adenosine Triphosphatases; Animals; Blood Chemical Analysis; Butea; Carbon Tetrachloride; Carbon Tet

2011
[Quantitative changes of rat's alpha 2 macroglobulin concentration by influence of carbon tetrachloride (author's transl)].
    Die Pharmazie, 1980, Volume: 35, Issue:2

    Topics: Alanine Transaminase; alpha-Macroglobulins; Aminopyrine; Animals; Body Weight; Carbon Tetrachloride

1980
Protective activities of aucubin against carbon tetrachloride-induced liver damage in mice.
    Drug and chemical toxicology, 1983, Volume: 6, Issue:5

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride Poisoning; Chemical

1983
The excretion of ascorbic acid and hippuric acid in the urine of rats with liver injury.
    Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement, 1980, Volume: 4

    Topics: Aminopyrine; Animals; Ascorbic Acid; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver

1980
Mechanism of protection against carbon tetrachloride toxicity. I. Prevention of lethal effects by partial surgical hepatectomy.
    Drug and chemical toxicology, 1982, Volume: 5, Issue:2

    Topics: Aminopyrine N-Demethylase; Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Hepatectom

1982
Experimental model of cirrhosis in rabbits exposed to carbon tetrachloride by inhalation.
    Research communications in molecular pathology and pharmacology, 1995, Volume: 88, Issue:1

    Topics: Administration, Inhalation; Animals; Body Weight; Carbon Tetrachloride Poisoning; Hexobarbital; Live

1995
3,4,5-Trihydroxy benzoic acid (gallic acid), the hepatoprotective principle in the fruits of Terminalia belerica-bioassay guided activity.
    Pharmacological research, 1997, Volume: 36, Issue:4

    Topics: Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Female; Gallic Acid

1997
[Liver extract effect on liver microsomal system and on an experimental model of intoxication].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1977, Volume: 171, Issue:2

    Topics: Animals; Carbon Tetrachloride Poisoning; Enzyme Induction; Hexobarbital; Liver Extracts; Male; Micro

1977
Modification of carbon tetrachloride hepatotoxicity by chemicals.
    Toxicology and applied pharmacology, 1977, Volume: 41, Issue:2

    Topics: Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injur

1977
[Sensitivity of female Wistar rats to carbon tetrachloride, determined by the LD50, and the hexobarbital sleeping time after a single oral dose].
    Zeitschrift fur Versuchstierkunde, 1979, Volume: 21, Issue:3

    Topics: Animals; Carbon Tetrachloride Poisoning; Female; Hexobarbital; Lethal Dose 50; Rats; Seasons; Sleep;

1979
[The excretion of hippuric acid and ascorbic acid in the urine of liver-damaged rats (author's transl].
    Die Pharmazie, 1979, Volume: 34, Issue:11

    Topics: Aminopyrine; Animals; Ascorbic Acid; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver

1979
Sex differences and sex hormones in experimental liver injury.
    Arzneimittel-Forschung, 1979, Volume: 29, Issue:6

    Topics: Animals; Biotransformation; Carbon Tetrachloride Poisoning; Castration; Chemical and Drug Induced Li

1979
Antagonism by chloramphenicol of carbon tetrachloride hepatotoxicity. Examination of microsomal cytochrome P-450 and lipid peroxidation.
    Experimental and molecular pathology, 1978, Volume: 28, Issue:1

    Topics: Animals; Carbon Tetrachloride Poisoning; Chloramphenicol; Cytochrome P-450 Enzyme System; Cytochrome

1978
Estrogens as disposing factors in experimental liver injury.
    Experimentelle Pathologie, 1978, Volume: 16, Issue:1-6

    Topics: Animals; Biotransformation; Carbon Tetrachloride Poisoning; Drug Interactions; Estrogens; Female; He

1978
Diethylnitrosamine-induced changes in mouse liver morphology and function.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1976, Volume: 153, Issue:1

    Topics: Animals; Carbon Tetrachloride Poisoning; Diethylnitrosamine; Hexobarbital; Liver; Liver Neoplasms; M

1976
[Enzyme activities in the blood serum of rats with chronic liver damage. 1. Effect of carbon tetrachloride].
    Die Pharmazie, 1976, Volume: 31, Issue:10

    Topics: Animals; Body Weight; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chroni

1976
The role of sex differences in the effect of anabolics on the liver.
    Arzneimittel-Forschung, 1975, Volume: 25, Issue:3

    Topics: Anabolic Agents; Anesthesia; Animals; Body Weight; Carbon Tetrachloride Poisoning; Chemical and Drug

1975
Biochemical aspects of the protective action of propyl gallate on liver injury in rats poisoned with carbon tetrachloride.
    Toxicology and applied pharmacology, 1975, Volume: 34, Issue:1

    Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Body Temperature;

1975
[Neurohumoral regulation of liver function].
    Acta pharmaceutica Hungarica, 1974, Volume: 44, Issue:3

    Topics: Animals; Carbon Tetrachloride Poisoning; Catecholamines; Hexobarbital; Liver; Neurotransmitter Agent

1974
The influence of a ganglion-blocking agent on experimental liver injury.
    Toxicology, 1973, Volume: 1, Issue:2

    Topics: Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Enzyme Induction; F

1973
Sympathetic receptor functions in liver damage.
    Arzneimittel-Forschung, 1974, Volume: 24, Issue:11

    Topics: Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Depression, Chemica

1974
[Effect of xanthinol-nicotinate on detoxification processes in liver. Experimental studies on the model of hexobarbital-narcosis in rat].
    Arzneimittel-Forschung, 1969, Volume: 19, Issue:12

    Topics: Anesthesia, General; Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Dru

1969
[Influencing of microsomal enzymes by carbon tetrachloride with and without phenobarbital pretreatment].
    Experientia, 1971, Mar-15, Volume: 27, Issue:3

    Topics: Aniline Compounds; Animals; Carbon Tetrachloride Poisoning; Cytochromes; Furaldehyde; Glucose-6-Phos

1971
[Effect of carbon tetrachloride on endoplasmic enzymes in rat liver].
    Archiv fur Toxikologie, 1971, Volume: 28, Issue:1

    Topics: Aminopyrine; Aniline Compounds; Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Choli

1971
Effect of phenobarbital or pregnenolone-16alpha-carbonitrile (PCN) pretreatment on acute carbon tetrachloride hepatotoxicity in rats.
    Biochemical pharmacology, 1974, Feb-01, Volume: 23, Issue:3

    Topics: Animals; Carbon Tetrachloride Poisoning; Cattle; Chemical and Drug Induced Liver Injury; Cytochrome

1974
Interference of DPPD with hepatic drug metabolizing enzyme system.
    Pharmacological research communications, 1974, Volume: 6, Issue:2

    Topics: Alanine Transaminase; Aminopyrine N-Demethylase; Animals; Antioxidants; Carbon Tetrachloride Poisoni

1974
Time course of protection by N'N--diphenyl-p-phenylendiamine (DPPD) against carbon tetrachloride hepatotoxicy.
    Agents and actions, 1974, Volume: 4, Issue:5

    Topics: Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical

1974
[The effect of silymarine on contents and functions of some microsomal liver enzymes influenced by carbon tetrachloride or halothane].
    Arzneimittel-Forschung, 1973, Volume: 23, Issue:9

    Topics: Alcohols; Aniline Compounds; Animals; Binding, Competitive; Carbon Tetrachloride Poisoning; Chromato

1973
Dimethylsulfoxide increases the lethality of CCl4 in rats but decreases its hepatotoxicity.
    Toxicology and applied pharmacology, 1974, Volume: 27, Issue:1

    Topics: Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injur

1974
Mechanism of protection against carbon tetrachloride by prior carbon tetrachloride administration.
    Experimental and molecular pathology, 1972, Volume: 16, Issue:3

    Topics: Administration, Oral; Animals; Carbon Dioxide; Carbon Isotopes; Carbon Tetrachloride; Carbon Tetrach

1972
[Binding of carbon tetrachloride to reduced microsomal cytochrome P-450 and to heme].
    Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1971, Volume: 352, Issue:8

    Topics: Animals; Binding Sites; Carbon Monoxide; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Cytoc

1971
Selective potentiation of carbon tetrachloride hepatotoxicity by ethanol.
    Archives internationales de pharmacodynamie et de therapie, 1971, Volume: 189, Issue:1

    Topics: Alanine Transaminase; Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Dr

1971
Effect of phenobarbital on the restoration of impaired drug metabolism in carbon tetrachloride-induced liver damage.
    Annales medicinae experimentalis et biologiae Fenniae, 1971, Volume: 49, Issue:3

    Topics: Animals; Body Weight; Carbon Tetrachloride Poisoning; Clinical Enzyme Tests; Cytochromes; Enzyme Act

1971
[Reduction of liver toxicity of carbon tetrachloride by diethyl thiocarbamate and 3-(O-tolyl)-4-(nitro)-syndnon].
    Acta biologica et medica Germanica, 1971, Volume: 27, Issue:2

    Topics: Anesthesia, Intravenous; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Carbon Tetrachl

1971
Effect of partial liver resection and phenobarbital on the restoration of impaired drug metabolism in carbon tetrachloride induced liver damage.
    Acta pharmacologica et toxicologica, 1971, Volume: 30, Issue:5

    Topics: Animals; Benzoates; Carbon Tetrachloride Poisoning; Cytochromes; Enzyme Induction; Hepatectomy; Hexo

1971
Hexobarbital sleeping time in male rats with hepatic injury.
    Acta physiologica Academiae Scientiarum Hungaricae, 1969, Volume: 36, Issue:4

    Topics: Acetates; Alcohols; Amides; Animals; Aspartate Aminotransferases; Benzene Derivatives; Biotransforma

1969
Effect of zinc sulphate on carbon tetrachloride hepatotoxicity.
    Acta pharmacologica et toxicologica, 1969, Volume: 27, Issue:6

    Topics: Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Hexobarbital; Injections, Intraperito

1969
Impairment of hepatic drug metabolism by carbon tetrachloride inhalation.
    Toxicology and applied pharmacology, 1970, Volume: 16, Issue:1

    Topics: Air; Animals; Carbon Tetrachloride Poisoning; Hexobarbital; In Vitro Techniques; Liver; Male; Organ

1970
[Toxicity, narcotic effect, blood level after awakening, elimination from the blood and biotransformation of hexobarbital in rats of different ages after induction with barbital and carbon tetrachloride poisoning].
    Archives internationales de pharmacodynamie et de therapie, 1970, Volume: 184, Issue:1

    Topics: Age Factors; Animals; Biotransformation; Carbon Tetrachloride Poisoning; Hexobarbital; Microsomes, L

1970
Further observations upon the effects of phenobarbital pretreatment on the hepatotoxicity of carbon tetrachloride.
    Experimental and molecular pathology, 1971, Volume: 14, Issue:2

    Topics: Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Endoplasmic Reticul

1971
The effects of aliphatic halogenated hydrocarbons on hepatic drug metabolism.
    Biochemical pharmacology, 1968, Volume: 17, Issue:7

    Topics: Aminopyrine; Animals; Antioxidants; Benzoates; Carbon Isotopes; Carbon Tetrachloride; Carbon Tetrach

1968
[Studies on the mechanism of enzyme induction. XII. Effect of liver damage by CCl-4].
    Acta biologica et medica Germanica, 1968, Volume: 20, Issue:1

    Topics: Animals; Ascorbic Acid; Barbiturates; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Live

1968
Effect of thyroxine on thioacetamide hepatotoxicity.
    Acta pharmacologica et toxicologica, 1968, Volume: 26, Issue:6

    Topics: Acetates; Amides; Animals; Carbon Tetrachloride Poisoning; Hexobarbital; Liver; Rats; Succinate Dehy

1968