hexobarbital has been researched along with Body Weight in 104 studies
Hexobarbital: A barbiturate that is effective as a hypnotic and sedative.
hexobarbital : A member of the class of barbiturates taht is barbituric acid substituted at N-1 by methyl and at C-5 by methyl and cyclohex-1-enyl groups.
Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Effects of furazolidone (FZ) on the sleeping time induced with hexobarbital (HEX) and paralysis time induced by zoxazolamine (ZOX) were investigated by measuring the length of time required to recover from righting reflex loss in rats after oral administration of FZ at doses of 50, 100, 200 and 400 mg/kg/day for 4 successive days." | 3.69 | Effects of furazolidone on duration of righting reflex loss induced with hexobarbital and zoxazolamine in the rat. ( Sasaki, N, 1994) |
| "Effects of multiple oral administration of enprostil ((+/-)-11 alpha,15 alpha-dihydroxy-9-oxo-16-phenoxy-17,18,19,20-tetranorprosta- 4,5,13(t)-trienoic acid methyl ester, TA 84135) (20 micrograms/kg/d) and its solvent propylene carbonate (PC, 100 microliters/kg/d) on body weight gain, liver weight, hepatic drug metabolizing enzyme system and hexobarbital sleeping time were investigated in male rats during a 14-day period." | 3.67 | Metabolic fate of the new anti-ulcer drug enprostil in animals. 4th communication: effect on hepatic drug metabolizing enzyme system in rats. ( Kohno, M; Nakahara, M; Otsuka, M; Takaiti, O; Yamada, Y, 1989) |
| " Chronic administration of selenium in the drinking water (1 or 2 ppm selenium) for 12 weeks, resulted in no alteration in any of the parameters measured." | 1.28 | Inhibition of hepatic mixed-function oxidase enzymes in mice by acute and chronic treatment with selenium. ( Ishikawa, M; Koiwai, K; Ozaki, M; Sasaki, K; Sasaki, M; Takayanagi, Y, 1992) |
| "Hexobarbital is a drug widely used to study the capacity of the liver to metabolize drugs." | 1.28 | Pharmacokinetics of hexobarbital in young and old rats. ( Boonstra-Nieveld, IH; van Bezooijen, CF, 1989) |
| " The acute oral LD50 of naphthalene was 533 and 710 mg/kg in male and female mice, respectively." | 1.27 | Naphthalene toxicity in CD-1 mice: general toxicology and immunotoxicology. ( Anderson, AC; Barnes, DW; Borzelleca, JF; Condie, LW; Duke, SS; Hayes, JR; Holsapple, MP; Shopp, GM; White, KL, 1984) |
| " The ip LD50 of CPA was found to be 13 +/- 0." | 1.27 | Toxicity and neuropharmacology of cyclopiazonic acid. ( Cole, RJ; Dorner, JW; Nishie, K, 1985) |
| "Chlordiazepoxide HCl, a widely used tranquilizer, was evaluated for pre- and postnatal effects in rats by dosing orally on days 1--21 of gestation." | 1.26 | Effects of chlordiazepoxide on the pre- and postnatal development of rats. ( Buttar, HS, 1980) |
| " However, chronic administration of lead to weanling rats caused no significant changes in hepatic cytochrome P-450 levels or in the microsomal oxidative enzymes over a 12-wk period." | 1.26 | Lead intoxication: effects on cytochrome P-450-mediated hepatic oxidations. ( Alvares, AP; Anderson, KE; Fischbein, A; Kappas, A; Sassa, S, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 97 (93.27) | 18.7374 |
| 1990's | 7 (6.73) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| QUEVAUVILLER, A | 1 |
| LAROCHE, MJ | 1 |
| COTTART, A | 1 |
| SACQUET, E | 1 |
| CHARLIER, E | 1 |
| Lee, NH | 1 |
| Hospado, MA | 1 |
| Manthei, RW | 1 |
| Schade, R | 1 |
| Rex, H | 1 |
| Kästner, D | 1 |
| Sprang, C | 1 |
| Jacob, V | 1 |
| Bolander, HG | 2 |
| Shopp, GM | 2 |
| White, KL | 2 |
| Holsapple, MP | 1 |
| Barnes, DW | 2 |
| Duke, SS | 1 |
| Anderson, AC | 1 |
| Condie, LW | 1 |
| Hayes, JR | 1 |
| Borzelleca, JF | 1 |
| Chang, YF | 1 |
| Hernandez, MF | 1 |
| Myslinski, NR | 1 |
| Nordberg, A | 1 |
| Wahlström, G | 2 |
| Kaneto, H | 1 |
| Kosaka, N | 1 |
| Takasu, M | 1 |
| Mino, T | 1 |
| Nikiforov, B | 1 |
| Tabacova, S | 1 |
| Sachan, DS | 2 |
| Buttar, HS | 2 |
| Bien, E | 2 |
| Skorka, G | 1 |
| Buntrock, P | 1 |
| Ugazio, G | 2 |
| Bosia, S | 1 |
| Cornaglia, E | 1 |
| Sasaki, N | 1 |
| Rommelspacher, H | 1 |
| Kauffmann, H | 1 |
| Cohnitz, CH | 1 |
| Coper, H | 2 |
| Benakis, A | 1 |
| Corthay, J | 1 |
| Medilanski, P | 1 |
| Holl, JE | 1 |
| Resurreccion, AV | 1 |
| Park, LE | 1 |
| Caster, WO | 5 |
| Nera, EA | 1 |
| Downie, RH | 1 |
| Schröder, S | 1 |
| Kuhlmey, B | 1 |
| O'Malley, K | 1 |
| Stevenson, IH | 2 |
| West, M | 1 |
| Cooper, DY | 1 |
| Schleyer, H | 1 |
| Thomas, JH | 1 |
| Vars, HM | 1 |
| Rosenthal, O | 1 |
| Kulcsár-Gergely, J | 1 |
| Kulcsár, A | 1 |
| Kiss, A | 1 |
| Pirola, RC | 1 |
| Lieber, CS | 1 |
| Gut, I | 1 |
| Becker, BA | 3 |
| Alvares, AP | 1 |
| Fischbein, A | 1 |
| Sassa, S | 1 |
| Anderson, KE | 1 |
| Kappas, A | 1 |
| Carlson, GP | 2 |
| Tardiff, RG | 1 |
| Ishikawa, M | 1 |
| Sasaki, M | 1 |
| Koiwai, K | 1 |
| Ozaki, M | 1 |
| Takayanagi, Y | 1 |
| Sasaki, K | 1 |
| Agrawal, AK | 1 |
| Pampori, NA | 1 |
| Shapiro, BH | 2 |
| Bosio, A | 1 |
| Nebbia, C | 1 |
| Soffietti, MG | 1 |
| Ahmad, N | 1 |
| Kartha, R | 1 |
| Miller-Podraza, H | 1 |
| Rakowska, M | 1 |
| Skarzyńska, E | 1 |
| Yamada, Y | 1 |
| Nakahara, M | 1 |
| Kohno, M | 1 |
| Otsuka, M | 1 |
| Takaiti, O | 1 |
| Gooderham, NJ | 1 |
| Mannering, GJ | 1 |
| Boonstra-Nieveld, IH | 1 |
| van Bezooijen, CF | 1 |
| Dobreva, V | 1 |
| Kaloianova, F | 1 |
| Niedermeyer, TM | 1 |
| Lovell, DP | 1 |
| Su, PK | 1 |
| Kourtopoulos, H | 1 |
| Kapeghian, JC | 1 |
| Jones, AB | 1 |
| Waters, IW | 1 |
| Nishie, K | 1 |
| Cole, RJ | 1 |
| Dorner, JW | 1 |
| Sanders, VM | 1 |
| Munson, AE | 1 |
| Poland, A | 1 |
| Goldstein, J | 1 |
| Hickman, P | 2 |
| Burse, VW | 1 |
| Emrich, D | 1 |
| Burmeister, G | 1 |
| Zimmermann, HD | 1 |
| Beckmann, R | 1 |
| Springfield, AC | 1 |
| DeFeo, JJ | 1 |
| Lison, H | 1 |
| Schlede, E | 1 |
| Borowski, R | 1 |
| Kato, R | 5 |
| Takanaka, A | 5 |
| Wilson, JT | 2 |
| Frohman, LA | 1 |
| Verschuuren, HG | 2 |
| Kroes, R | 2 |
| den Tonkelaar, EM | 2 |
| Oshima, T | 1 |
| Takahashi, A | 1 |
| Onoda, K | 2 |
| Peters, MA | 1 |
| Fouts, JR | 2 |
| Grosse, W | 1 |
| Wade, AE | 6 |
| Vorne, M | 3 |
| Arvela, P | 1 |
| Stitzel, RE | 2 |
| Wu, B | 2 |
| Rating, D | 1 |
| Broermann, I | 1 |
| Honecker, H | 1 |
| Kluwe, S | 1 |
| Lawrence, WH | 1 |
| Malik, M | 1 |
| Turner, JE | 1 |
| Autian, J | 2 |
| Sofia, RD | 1 |
| Szabo, S | 1 |
| Kovacs, K | 1 |
| Garg, BD | 1 |
| Tuchweber, B | 1 |
| Lazar, G | 1 |
| Wu, BC | 1 |
| Holbrook, CM | 1 |
| Miranda, CL | 1 |
| Webb, RE | 1 |
| Saito, FU | 1 |
| Kocsis, JJ | 1 |
| Snyder, R | 1 |
| Funcke, AB | 1 |
| Timmerman, H | 1 |
| Goldstein, JA | 1 |
| Kimbrough, RD | 1 |
| Gringmuth-Dallmer, H | 1 |
| Buzello, W | 1 |
| Scholler, KL | 1 |
| Schöppe, B | 1 |
| Hadley, WM | 1 |
| Miya, TS | 2 |
| Bousquet, WF | 2 |
| Siami, G | 1 |
| Schulert, AR | 1 |
| Neal, RA | 1 |
| Smith, PB | 1 |
| Vassanelli, P | 1 |
| Chiesara, E | 1 |
| Hatfield, GK | 1 |
| Prabhu, VG | 1 |
| Oester, YT | 1 |
| Alavaikko, M | 1 |
| Furner, RL | 1 |
| Gram, TE | 1 |
| Mikhaĭlei, GA | 1 |
| Volynskaia, SL | 2 |
| Ivanov, NI | 1 |
| Sloniikaia, NN | 1 |
| Hässler, A | 1 |
| Bräunlich, H | 2 |
| Ankermann, H | 1 |
| Greene, FE | 2 |
| Meadows, JS | 2 |
| Eling, TE | 1 |
| Harbison, RD | 2 |
| Kaschnitz, R | 1 |
| Quaife, ML | 1 |
| Friedman, L | 1 |
| Dairman, W | 1 |
| Balazs, T | 1 |
| Gerald, MC | 1 |
| Feller, DR | 1 |
| Clark, R | 1 |
| Lynes, TE | 1 |
| Price, WA | 1 |
| Smith, DH | 1 |
| Woodward, JK | 1 |
| Marvel, JP | 1 |
| Vernier, VG | 1 |
| Wagstaff, DJ | 1 |
| Short, CR | 1 |
| Merte, K | 1 |
| Leuschner, F | 1 |
| Leuschner, A | 1 |
| Dumova, AM | 1 |
| Kravchuk, TD | 1 |
| Pearl, W | 1 |
| Kupfer, D | 1 |
| Fujii, K | 1 |
| Jaffe, H | 1 |
| Epstein, SS | 1 |
| Turnbull, MJ | 1 |
| Hahn, G | 1 |
| Lehmann, HD | 1 |
| Kürten, M | 1 |
| Uebel, H | 1 |
| Vogel, G | 1 |
| Kalser, SC | 1 |
| Kunig, R | 1 |
| Calley, D | 1 |
| Guess, WL | 1 |
| Jondorf, WR | 1 |
| Simon, DC | 1 |
| Avnimelech, M | 1 |
104 other studies available for hexobarbital and Body Weight
| Article | Year |
|---|---|
[ANESTHETIC ACTIVITY AND COMPARATIVE METABOLISM OF HEXOBARBITAL IN THE GERM-FREE AND CONVENTIONAL MOUSE].
Topics: Anesthesia; Anesthetics; Animals; Body Weight; Germ-Free Life; Hexobarbital; Liver; Metabolism; Mice | 1964 |
Influence of age and dietary stress on hexobarbital activity in mice.
Topics: Aging; Animals; Body Weight; Diet; Dietary Carbohydrates; Dietary Proteins; Hexobarbital; In Vitro T | 1967 |
[Quantitative changes of rat's alpha 2 macroglobulin concentration by influence of carbon tetrachloride (author's transl)].
Topics: Alanine Transaminase; alpha-Macroglobulins; Aminopyrine; Animals; Body Weight; Carbon Tetrachloride | 1980 |
Age-related changes in CNS-sensitivity to hexobarbital and thiopental in the rat.
Topics: Aging; Anesthesia; Animals; Body Weight; Brain; Brain Chemistry; Electroencephalography; Hexobarbita | 1984 |
Naphthalene toxicity in CD-1 mice: general toxicology and immunotoxicology.
Topics: Animals; Antibody Formation; Blood Coagulation; Body Weight; Enzymes; Female; Hexobarbital; Immunity | 1984 |
Enhancement of hexobarbital-induced sleep by lysine and its metabolites.
Topics: Age Factors; Animals; Body Weight; Drug Synergism; Hexobarbital; Lysine; Male; Pipecolic Acids; Pipe | 1981 |
Tolerance, physical dependence and changes in muscarinic receptor binding sites after chronic ethanol treatment in the rat.
Topics: Alcoholism; Animals; Atropine; Binding Sites; Body Weight; Drug Tolerance; Hexobarbital; Humans; Mal | 1982 |
[Studies on the physical dependence liability to guanabenz].
Topics: Analgesics; Animals; Antihypertensive Agents; Barbital; Body Weight; Drug Synergism; Guanabenz; Guan | 1982 |
Activity of some mixed function oxidases in prenatally carbon disulphide (CS2) treated rats.
Topics: Animals; Body Weight; Carbon Disulfide; Female; Hexobarbital; Liver; Mixed Function Oxygenases; Orga | 1980 |
Modulation of drug metabolism by food restriction in male rats.
Topics: Animals; Body Weight; Cytochrome P-450 Enzyme System; Food Deprivation; Guanosine Diphosphate; Hexob | 1982 |
Effects of chlordiazepoxide on the pre- and postnatal development of rats.
Topics: Animals; Animals, Newborn; Body Weight; Chlordiazepoxide; Female; Fetus; Hexobarbital; Male; Pregnan | 1980 |
[Hepatotoxicological studies of pyrazolone derivatives on rats. Part 2: The study of propyphenazone and phenazone (author's transl)].
Topics: Aminopyrine N-Demethylase; Animals; Antipyrine; Body Weight; Chemical and Drug Induced Liver Injury; | 1981 |
Experimental model of cirrhosis in rabbits exposed to carbon tetrachloride by inhalation.
Topics: Administration, Inhalation; Animals; Body Weight; Carbon Tetrachloride Poisoning; Hexobarbital; Live | 1995 |
Effects of furazolidone on duration of righting reflex loss induced with hexobarbital and zoxazolamine in the rat.
Topics: Administration, Oral; Animals; Body Weight; Cytochrome P-450 Enzyme System; Dose-Response Relationsh | 1994 |
Pharmacological properties of tetrahydronorharmane (tryptoline).
Topics: Analgesics; Animals; Apomorphine; Body Temperature; Body Weight; Brain; Carbolines; Drinking; Drug I | 1977 |
Effect of feeding irradiated fish on the drug-metabolizing liver enzymes in rats.
Topics: Animals; Body Weight; Cytochrome P-450 Enzyme System; Eating; Fishes; Food Preservation; Hexobarbita | 1977 |
Barbiturate and amphetamine activity in rats fed a magnesium-deficient diet.
Topics: Animals; Body Weight; Dextroamphetamine; Diet; Hexobarbital; Hypnotics and Sedatives; Lethal Dose 50 | 1978 |
Serum enzyme activities and hepatic triglyceride levels in acute and subacute acetaminophen-treated rats.
Topics: Acetaminophen; Alanine Transaminase; Animals; Aspartate Aminotransferases; Body Weight; Hexobarbital | 1976 |
[Enzyme activities in the blood serum of rats with chronic liver damage. 1. Effect of carbon tetrachloride].
Topics: Animals; Body Weight; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chroni | 1976 |
The effect of fenfluramine on disposition and rate of antipyrine elimination.
Topics: Adolescent; Adult; Animals; Antipyrine; Body Height; Body Weight; Female; Fenfluramine; Half-Life; H | 1975 |
Comparison of the induction course, biophysical chemical interactions and photochemical action spectra of phenobarbital and 3-methylcholanthrene induce hepatic microsomal P-450.
Topics: Aniline Compounds; Animals; Biotransformation; Body Weight; Carbon Monoxide; Codeine; Cytochrome P-4 | 1975 |
The role of sex differences in the effect of anabolics on the liver.
Topics: Anabolic Agents; Anesthesia; Animals; Body Weight; Carbon Tetrachloride Poisoning; Chemical and Drug | 1975 |
Energy wastage in rats given drugs that induce microsomal enzymes.
Topics: Aminopyrine; Animals; Barbiturates; Body Weight; Energy Metabolism; Enzyme Induction; Ethanol; Femal | 1975 |
Diphenylhydantoin effects on hexobarbital and aniline biotransformation in male rats: differences between in vitro and in vivo observations.
Topics: Aniline Compounds; Animals; Biotransformation; Body Weight; Hexobarbital; In Vitro Techniques; Liver | 1975 |
Lead intoxication: effects on cytochrome P-450-mediated hepatic oxidations.
Topics: Adult; Aniline Hydroxylase; Animals; Antipyrine; Body Weight; Cytochrome P-450 Enzyme System; Ethylm | 1976 |
Effect of chlorinated benzenes on the metabolism of foreign organic compounds.
Topics: Animals; Body Weight; Chemical and Drug Induced Liver Injury; Chlorobenzenes; Hexachlorobenzene; Hex | 1976 |
Inhibition of hepatic mixed-function oxidase enzymes in mice by acute and chronic treatment with selenium.
Topics: 7-Alkoxycoumarin O-Dealkylase; Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Body Weight; | 1992 |
Sex- and dose-dependent effects of neonatally administered aspartate on the ultradian patterns of circulating growth hormone regulating hexobarbital metabolism and action.
Topics: Animals; Animals, Newborn; Aspartic Acid; Body Weight; Dose-Response Relationship, Drug; Female; Hex | 1991 |
Age- and sex-related effects on hepatic drug metabolism in rats chronically exposed to dietary atrazine.
Topics: Age Factors; Aminopyrine; Aniline Compounds; Animals; Atrazine; Body Weight; Enzyme Induction; Femal | 1991 |
Effects of nitrogen compounds with hexobarbital induced sleep in Swiss albino mice.
Topics: Animals; Body Weight; Female; Hexobarbital; Mice; Mixed Function Oxygenases; Nitrogen; Sleep | 1991 |
Lack of major effects of ethanol, chlorpromazine, hexobarbital and haloperidol on brain gangliosides.
Topics: Animals; Body Weight; Brain; Chlorpromazine; Ethanol; Gangliosides; Haloperidol; Hexobarbital; Male; | 1990 |
Metabolic fate of the new anti-ulcer drug enprostil in animals. 4th communication: effect on hepatic drug metabolizing enzyme system in rats.
Topics: Animals; Anti-Ulcer Agents; Body Weight; Enprostil; Hexobarbital; Liver; Male; Microsomes, Liver; Mi | 1989 |
Depression of the hepatic cytochrome P-450 monooxygenase system by treatment of mice with the antineoplastic agent 5-azacytidine.
Topics: Animals; Azacitidine; Body Weight; Cytochrome b Group; Cytochrome P-450 Enzyme System; Cytochromes b | 1985 |
Pharmacokinetics of hexobarbital in young and old rats.
Topics: Age Factors; Animals; Body Weight; Chromatography, High Pressure Liquid; Hexobarbital; Liver; Male; | 1989 |
[Changes in the hexobarbital sleep and serum cholinesterase activity of rats treated with carbaryl].
Topics: Animals; Body Weight; Carbaryl; Cholinesterases; Hexobarbital; Liver; Male; Organ Size; Rats; Sleep; | 1988 |
Selective androgen insensitivity of hepatic drug-metabolizing enzymes in senescent mice.
Topics: Aging; Animals; Body Weight; Female; Hexobarbital; Liver; Male; Mice; Mice, Inbred ICR; Microsomes, | 1988 |
Variation in pentobarbitone sleeping time in mice. 2. Variables affecting test results.
Topics: Age Factors; Animals; Body Weight; Dose-Response Relationship, Drug; Fasting; Female; Hexobarbital; | 1986 |
Effects of levels of feed restriction on in vivo and in vitro alterations in drug metabolism and associated enzymes.
Topics: Animals; Body Weight; Diet; DNA; Hexobarbital; In Vitro Techniques; Liver; Male; Mixed Function Oxyg | 1986 |
Effects of castration and testosterone treatment on the hexobarbital sensitivity in male rats.
Topics: Animals; Body Weight; Castration; Dose-Response Relationship, Drug; Electroencephalography; Hexobarb | 1985 |
Effects of ammonia on selected hepatic microsomal enzyme activity in mice.
Topics: Aminopyrine N-Demethylase; Ammonia; Aniline Hydroxylase; Animals; Body Weight; Hexobarbital; Male; M | 1985 |
Toxicity and neuropharmacology of cyclopiazonic acid.
Topics: Animals; Body Weight; Chlorpromazine; Electrocardiography; Electroencephalography; Heart Rate; Hexob | 1985 |
Toxicology of trans-1,2-dichloroethylene in the mouse.
Topics: Animals; Blood Cell Count; Blood Urea Nitrogen; Body Weight; Drinking; Enzymes; Ethylene Dichlorides | 1985 |
A reciprocal relationship between the induction of -aminolevulinic acid synthetase and drug metabolism produced by m-dichlorobenzene.
Topics: Acyltransferases; Animals; Benzene Derivatives; Body Weight; Chemical and Drug Induced Liver Injury; | 1971 |
The effect of iodine deficiency and suppression of TSH secretion on radioiodine labelled thyroxine and triiodothyronine in the thyroid of rats.
Topics: Animals; Body Weight; Deficiency Diseases; Diet; Electrocardiography; Hexobarbital; Injections, Subc | 1971 |
Liver enlargement and modification of hepatic microsomal drug metabolism in rats by pyrethrum.
Topics: Aminopyrine; Animals; Anisoles; Body Weight; Chrysanthemum cinerariifolium; Colorimetry; Cytochrome | 1973 |
[Differentiation of functional disturbances of the central nervous system evoked by 6-aminonicotinamide, an antimetabolite of nicotinamide].
Topics: Animals; Antimetabolites; Blood Glucose; Body Temperature; Body Weight; Extrapyramidal Tracts; Femal | 1970 |
Decreased effect of phenobarbital treatment on microsomal drug metabolizing enzyme activity during gestation.
Topics: Animals; Benzopyrenes; Body Weight; Cytochrome P-450 Enzyme System; Dealkylation; Depression, Chemic | 1974 |
Effect of starvation on the in vivo metabolism and effect of drugs in female and male rats.
Topics: Amides; Anesthesia; Animals; Barbiturates; Body Weight; Carisoprodol; Diphosphates; Female; Hexobarb | 1967 |
Concomitant association between high plasma levels of growth hormone and low hepatic mixed-function oxidase activity in the young rat.
Topics: Age Factors; Aminopyrine; Aniline Compounds; Animals; Animals, Newborn; Body Weight; Cytochrome c Gr | 1974 |
Toxicity studies on tertrasul. II. Short-term comparative studies in 6 animal species.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Body Weight; Chickens; Diet; Female; Glucose-6- | 1973 |
Toxicity studies on tetrasul. 3. Short-term comparative studies in rats with tetrasul and structurally related acaricides.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Benzenesulfonates; Blood Cell Count; Body Weigh | 1973 |
Metabolism of drugs in old rats. I. Activities of NADPH-linked electron transport and drug-metabolizing enzyme systems in liver microsomes of old rats.
Topics: Aging; Aminobenzoates; Aminopyrine; Aniline Compounds; Animals; Azo Compounds; Benzoates; Body Weigh | 1968 |
Effect of vitamin C deficiency on the metabolism of drugs and NADPH-linked electron transport system in liver microsomes.
Topics: Aminopyrine; Aniline Compounds; Animals; Ascorbic Acid; Ascorbic Acid Deficiency; Body Weight; Diphe | 1969 |
Species differences in the alteration of drug-metabolizing activities of liver microsomes by thyroxine treatment.
Topics: Aminopyrine; Aniline Compounds; Animals; Body Weight; Electron Transport; Female; Heart; Hexobarbita | 1969 |
The inhibitory effect of aureomycin (chlortetracycline) pretreatment on some rat liver microsomal enzyme activities.
Topics: Albumins; Aminopyrine; Animals; Body Weight; Chlortetracycline; Cytochromes; Depression, Chemical; H | 1969 |
The effect of thiamine consumption on liver microsomal drug-metabolizing pathways.
Topics: Aminopyrine; Aniline Compounds; Animals; Body Weight; Cytochromes; Diet; Esterases; Female; Glucosep | 1971 |
Effect of carbon tetrachloride induced progressive liver damage on drug-metabolizing enzymes and cytochrome P-450 in rat liver.
Topics: Aniline Compounds; Animals; Body Weight; Carbon Tetrachloride; Cytochromes; Glucosephosphate Dehydro | 1971 |
Effects of reserpine pretreatment on microsomal enzyme activity.
Topics: Aniline Compounds; Animals; Body Weight; Guinea Pigs; Hexobarbital; Liver; Male; Microsomes, Liver; | 1974 |
Withdrawal in the rat after long-term forced oral barbital administration.
Topics: Administration, Oral; Animals; Body Weight; Depression, Chemical; Drinking Behavior; Drug Tolerance; | 1974 |
Relationship of dietary essential fatty acid consumption to hepatic drug hydroxylation.
Topics: Aniline Compounds; Animals; Arachidonic Acids; Body Weight; Cytochrome P-450 Enzyme System; Cytochro | 1972 |
Effect of subchronic treatment with (-) 8 -trans-tetrahydrocannabinol ( 8 -THC) on food intake, body temperature, hexobarbital sleeping time and hexobarbital elimination in rats.
Topics: Animals; Body Temperature; Body Weight; Brain; Cannabis; Dronabinol; Drug Interactions; Feeding Beha | 1972 |
Toxicity profile of epichlorohydrin.
Topics: Administration, Intranasal; Administration, Oral; Animals; Blood Pressure; Body Weight; Cell Line; C | 1972 |
Interactions of chronic and acute 1 -tetrahydrocannabinol pretreatment with zoxazolamine and barbiturates.
Topics: Animals; Barbiturates; Body Weight; Cannabis; Dronabinol; Drug Interactions; Drug Synergism; Hexobar | 1973 |
Effect of hypophysectomy and cyproterone acetate on the liver ultrastructure as well as on hexobarbital anesthesia and zoxazolamine paralysis in rats.
Topics: Androgen Antagonists; Animals; Body Weight; Cyproterone; Enzyme Induction; Female; Hexobarbital; Hyp | 1973 |
Effects of thiamin antagonists on drug hydroxylation and properties of cytochrome P-450 in the rat.
Topics: Aniline Compounds; Animals; Antimetabolites; Binding, Competitive; Body Weight; Cytochrome P-450 Enz | 1973 |
Effects of dietary protein quality on drug metabolism in the rat.
Topics: Anesthesia; Aniline Compounds; Animals; Body Weight; Caseins; Cytochrome P-450 Enzyme System; Dealky | 1973 |
Effect of benzene on hepatic drug metabolism and ultrastructure.
Topics: Animals; Azo Compounds; Benzene; Benzene Derivatives; Benzoates; Body Weight; Carbon Radioisotopes; | 1973 |
Comparison of phenobarbital with orphenadrine hydrochloride and tofenacine hydrochloride for enzyme-inducing activity in young and adult rats.
Topics: Aging; Animals; Benzene Derivatives; Body Weight; Drug Tolerance; Enzyme Induction; Ethers; Ethylami | 1973 |
Effects of purified and technical piperonyl butoxide on drug-metabolizing enzymes and ultrastructure of rat liver.
Topics: Aniline Compounds; Animals; Appetite; Body Weight; Cytochrome P-450 Enzyme System; Diet; Endoplasmic | 1973 |
[Anesthesia for short-term gynecologic survey].
Topics: Adult; Age Factors; Aged; Anesthesia, General; Anesthesia, Inhalation; Body Weight; Female; Gynecolo | 1973 |
[Studies in mice on the effectiveness of various methods of enzyme induction with phenobarbital].
Topics: Administration, Oral; Animals; Body Weight; Dose-Response Relationship, Drug; Enzyme Induction; Fema | 1973 |
Cadmium inhibition of hepatic drug metabolism in the rat.
Topics: Acetates; Aminopyrine; Animals; Anisoles; Body Weight; Cadmium; Carbon Radioisotopes; Cytochrome P-4 | 1974 |
A possible role for the mixed function oxidase enzyme system in the requirement for selenium in the rat.
Topics: Aminopyrine; Animals; Body Weight; Castration; Deficiency Diseases; Estradiol; Female; Feminization; | 1972 |
Effects of ascorbic acid deficiency on kinetics of drug hydroxylation in male guinea pigs.
Topics: Aniline Compounds; Animals; Ascorbic Acid; Ascorbic Acid Deficiency; Body Weight; Cytochromes; Guine | 1972 |
Microsomal drug-metabolizing enzymes activity and induction in the rat liver after portacaval shunt.
Topics: Animals; Body Weight; Enzyme Induction; Hexobarbital; Male; Microsomes, Liver; Organ Size; Phenobarb | 1972 |
Ethanol tolerance and ethanol-drug interactions in the rat.
Topics: Animals; Barbiturates; Behavior, Animal; Body Weight; Depression, Chemical; Drug Interactions; Drug | 1972 |
Neuromuscular functions of mature mice following neonatal monosodium glutamate.
Topics: Animals; Animals, Newborn; Body Weight; Crowding; Dextroamphetamine; Female; Food Additives; Glutama | 1971 |
Effect of phenobarbital on the restoration of impaired drug metabolism in carbon tetrachloride-induced liver damage.
Topics: Animals; Body Weight; Carbon Tetrachloride Poisoning; Clinical Enzyme Tests; Cytochromes; Enzyme Act | 1971 |
Effect of carbon tetrachloride induced progressive liver damage on the metabolism of hexobarbital and bilirubin in vivo.
Topics: Animals; Bilirubin; Body Weight; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Hexob | 1971 |
Studies on age difference in mice for the activity of drug-metabolizing enzymes of liver microsomes.
Topics: Aging; Aminopyrine; Anesthesia; Aniline Compounds; Animals; Body Weight; Cytochromes; Electron Trans | 1970 |
Factors affecting the metabolism and response to hexobarbital.
Topics: Age Factors; Animals; Body Weight; Breeding; Female; Hexobarbital; Liver; Male; Methylcholanthrene; | 1969 |
[Toxicity of Levorin for laboratory animals in chronic experiments].
Topics: Anesthesia; Animals; Antifungal Agents; Bilirubin; Blood Proteins; Body Weight; Bronchopneumonia; Ca | 1969 |
[Significance of breeding conditions for duration of the hexobarbital effect and its individual variations in rats].
Topics: Age Factors; Animals; Body Weight; Breeding; Hexobarbital; Rats; Sex Factors; Starvation; Temperatur | 1969 |
Effect of thiamine and dietary linoleate levels on hepatic drug metabolism in the male rat.
Topics: Aniline Compounds; Animals; Biotransformation; Body Weight; Bridged-Ring Compounds; Depression, Chem | 1969 |
Diphenylhydantoin effect on neonatal and adult rat hepatic drug metabolism.
Topics: Age Factors; Aminopyrine; Aniline Compounds; Animals; Animals, Newborn; Benzoates; Benzopyrenes; Ben | 1970 |
Aryl 4-hydroxylase, cytochrome P-450 and microsomal lipids in essential fatty acid deficiency.
Topics: Aniline Compounds; Animals; Body Weight; Cytochromes; Deficiency Diseases; Fatty Acids, Essential; H | 1970 |
Effect of different levels of corn oil in the diet upon the rate of hexobarbital, heptachlor and aniline metabolism in the liver of the male white rat.
Topics: Aniline Compounds; Animals; Body Weight; Dietary Fats; Hexobarbital; Hydrocarbons, Halogenated; Inse | 1970 |
Failure of the vitamin E-deficient rat to show decreased liver codeine-O-demethylase activity.
Topics: Animals; Biotransformation; Body Weight; Codeine; Enzyme Induction; Hexobarbital; Liver; Male; Morph | 1970 |
Comparison of liver microsome enzyme systems and barbiturate sleep times in rats caged individually or communally.
Topics: Adrenal Glands; Aniline Compounds; Animals; Barbiturates; Body Weight; Crowding; Hexobarbital; In Vi | 1970 |
Evidence for spironolactone as a possible inducer of liver microsomal enzymes in mice.
Topics: Aniline Compounds; Animals; Body Weight; Enzyme Induction; Hexobarbital; Liver; Male; Metabolism; Mi | 1970 |
The pharmacology and toxicology of midaflur.
Topics: Analgesics; Animals; Appetite; Avoidance Learning; Benzimidazoles; Body Temperature; Body Weight; Ca | 1971 |
Induction of hepatic microsomal hydroxylating enzymes by technical piperonyl butoxide and some of its analogs.
Topics: Animals; Anisoles; Biotransformation; Body Weight; Cytochromes; Dioxoles; Enzyme Induction; Ethers, | 1971 |
[Age dependence of the narcotic effects of thiopental, Brevinarcon and hexobarbitol on rats].
Topics: Adipose Tissue; Age Factors; Anesthesia; Animals; Barbiturates; Body Weight; Female; Hexobarbital; M | 1967 |
[Comparative experimental animal studies with wines from hybrid and European vines].
Topics: Alcohols; Animals; Body Weight; Electroshock; Fatty Liver; Female; Hematopoiesis; Hexobarbital; Hybr | 1967 |
[Effect of tetracycline and morphocycline on some liver functions in animals].
Topics: Anesthesia; Animals; Anti-Bacterial Agents; Body Weight; Fats; Guinea Pigs; Hexobarbital; Liver; Mal | 1968 |
The effect of a pituitary mammotropic tumor on hepatic microsomal drug metabolism in the rat.
Topics: Adenocarcinoma; Adrenal Glands; Aminopyrine; Aniline Compounds; Animals; Benzoates; Benzopyrenes; Bo | 1968 |
Effect of 1-benzyl-2-thio-5,6-dihydrouracil on hepatic metabolic activity in the rat.
Topics: Animals; Body Weight; Carbon Isotopes; Cycloheximide; Depression, Chemical; Hexobarbital; Hydrocorti | 1968 |
Factors influencing the hexobarbital sleeping time and zoxazolamine paralysis time in mice.
Topics: Animal Nutritional Physiological Phenomena; Animals; Biological Assay; Body Weight; Female; Hexobarb | 1968 |
Hepatic drug-metabolising enzyme activity and duration of hexobarbitone anaesthesia in barbitone-dependent and withdrawn rats.
Topics: Anesthesia; Animals; Barbiturates; Body Weight; Drug Tolerance; Female; Hexobarbital; Humans; Liver; | 1968 |
[On the pharmacology and toxicology of silymarin, an antihepatotoxic active principle from Silybum marianum (L.) Gaertn].
Topics: Abnormalities, Drug-Induced; Amides; Animals; Body Weight; Carbon Tetrachloride; Dogs; Drug Synergis | 1968 |
Effect of varying periods of cold exposure on the action and metabolism of hexobarbital.
Topics: Adaptation, Physiological; Animals; Body Weight; Brain; Cold Temperature; Environmental Exposure; He | 1969 |
Barbiturate mortality in hypothyroid and hyperthyroid rats.
Topics: Amobarbital; Animals; Barbiturates; Basal Metabolism; Body Temperature; Body Weight; Hexobarbital; H | 1969 |
Toxicology of a series of phthalate esters.
Topics: Animals; Blood Cells; Blood Pressure; Body Weight; Brain; Chromatography, Thin Layer; Hexobarbital; | 1966 |
Further studies on the stimulation of L-(14C)-amino acid incorporation with cycloheximide.
Topics: Aminopyrine; Aniline Compounds; Animals; Antifungal Agents; Antipyrine; Body Weight; Carbon Isotopes | 1966 |