Page last updated: 2024-10-28

hexobarbital and Alloxan Diabetes

hexobarbital has been researched along with Alloxan Diabetes in 9 studies

Hexobarbital: A barbiturate that is effective as a hypnotic and sedative.
hexobarbital : A member of the class of barbiturates taht is barbituric acid substituted at N-1 by methyl and at C-5 by methyl and cyclohex-1-enyl groups.

Research Excerpts

ExcerptRelevanceReference
"ICRF-187, (+)-1,2-bis(3,5-dioxopiperazine-1-yl)propane, has been shown to protect against alloxan diabetes (el-Hage et al."3.67Mechanism of the protective activity of ICRF-187 against alloxan-induced diabetes in mice. ( Crouch, RK; el-Hage, A; Ferrans, VJ; Herman, EH; Yang, GC, 1986)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19909 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
DIXON, RL1
HART, LG1
ROGERS, LA1
FOUTS, JR1
el-Hage, A1
Herman, EH1
Yang, GC1
Crouch, RK1
Ferrans, VJ1
Chakravarthy, BK1
Patel, RB1
Gandhi, TP1
Patel, A1
Gilbert, RN1
Kato, R5
Gillette, JR1
Weiner, M1
Buterbaugh, GG1
Blake, DA1
Takanaka, A3
Onoda, K3

Other Studies

9 other studies available for hexobarbital and Alloxan Diabetes

ArticleYear
THE METABOLISM OF DRUGS BY LIVER MICROSOMES FROM ALLOXAN-DIABETIC RATS: LONG TERM DIABETES.
    The Journal of pharmacology and experimental therapeutics, 1963, Volume: 142

    Topics: Alloxan; Aminopyrine; Aniline Compounds; Animals; Codeine; Diabetes Mellitus, Experimental; Hexobarb

1963
Mechanism of the protective activity of ICRF-187 against alloxan-induced diabetes in mice.
    Research communications in chemical pathology and pharmacology, 1986, Volume: 52, Issue:3

    Topics: Alloxan; Animals; Blood Glucose; Chelating Agents; Cimetidine; Diabetes Mellitus, Experimental; Dime

1986
Variation of drug responses in diabetic rats under environmental stress.
    Indian journal of experimental biology, 1987, Volume: 25, Issue:9

    Topics: Animals; Cold Temperature; Dexamethasone; Diabetes Mellitus, Experimental; Female; Hexobarbital; Hot

1987
Sex differences in the effects of abnormal physiological states on the metabolism of drugs by rat liver microsomes.
    The Journal of pharmacology and experimental therapeutics, 1965, Volume: 150, Issue:2

    Topics: Adrenalectomy; Adrenocorticotropic Hormone; Aminopyrine; Aniline Compounds; Animals; Castration; Dia

1965
Inhibition of hepatic drug metabolism by cyclic 3',5'-adenosine monophosphate.
    Research communications in chemical pathology and pharmacology, 1972, Volume: 3, Issue:2

    Topics: Aniline Compounds; Animals; Bucladesine; Cyclic AMP; Diabetes Mellitus, Experimental; Glucagon; Hexo

1972
Effect of adrenalectomy or alloxan diabetes on the substrate interaction with cytochrome P-450 in the oxidation of drugs by liver microsomes.
    Biochemical pharmacology, 1971, Volume: 20, Issue:2

    Topics: Adrenal Glands; Adrenalectomy; Aminopyrine; Aniline Compounds; Animals; Cytochromes; Diabetes Mellit

1971
Substrate interaction with P-450 in the hydroxylation of drugs under abnormal physiological states.
    Advances in cytopharmacology, 1971, Volume: 1

    Topics: Adrenal Glands; Adrenalectomy; Aminopyrine; Androgens; Aniline Compounds; Animals; Biotransformation

1971
Species difference in drug metabolism by liver microsomes in alloxan diabetic or fasted animals. I. The activity of drug-metabolizing enzymes and electron transport system.
    Japanese journal of pharmacology, 1970, Volume: 20, Issue:4

    Topics: Aminopyrine; Aniline Compounds; Animals; Cytochromes; Diabetes Mellitus, Experimental; Electron Tran

1970
Species difference in drug metabolism by liver microsomes in alloxan diabetic or fasted animals. II. The substrate interaction with cytochrome P-450 in drug oxidation.
    Japanese journal of pharmacology, 1970, Volume: 20, Issue:4

    Topics: Aniline Compounds; Animals; Cytochromes; Diabetes Mellitus, Experimental; Fasting; Female; Hexobarbi

1970