hexestrol has been researched along with Fatty Liver in 5 studies
Fatty Liver: Lipid infiltration of the hepatic parenchymal cells resulting in a yellow-colored liver. The abnormal lipid accumulation is usually in the form of TRIGLYCERIDES, either as a single large droplet or multiple small droplets. Fatty liver is caused by an imbalance in the metabolism of FATTY ACIDS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Drugs rarely cause steatohepatitis, but amiodarone, perhexiline, and DH, have unequivocally been found to independently induce the histologic picture of alcoholic liver disease or NASH." | 2.42 | Drug-induced steatohepatitis. ( Sanyal, AJ; Stravitz, RT, 2003) |
| "In conclusion, steatohepatitis-inducing drugs increase cell calcium and activate tissue transglutaminase, which cross-links CK8 to form a molecular scaffold, from which MDB might secondarily arise." | 1.35 | Steatohepatitis-inducing drugs trigger cytokeratin cross-links in hepatocytes. Possible contribution to Mallory-Denk body formation. ( Berson, A; Descatoire, V; Pessayre, D; Robin, MA, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Robin, MA | 2 |
| Descatoire, V | 1 |
| Pessayre, D | 2 |
| Berson, A | 2 |
| Stravitz, RT | 1 |
| Sanyal, AJ | 1 |
| De Beco, V | 1 |
| Lettéron, P | 1 |
| Moreau, C | 1 |
| El Kahwaji, J | 1 |
| Verthier, N | 1 |
| Feldmann, G | 1 |
| Fromenty, B | 1 |
| Zimmerman, HJ | 1 |
| Kubo, M | 1 |
| Hostetler, KY | 1 |
2 reviews available for hexestrol and Fatty Liver
| Article | Year |
|---|---|
Drug-induced steatohepatitis.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Antineoplastic Agents, Hormonal; Calcium Channel Blocke | 2003 |
Drug-induced chronic hepatic disease.
Topics: Carcinoma, Hepatocellular; Chemical and Drug Induced Liver Injury; Chronic Disease; Fatty Liver; Hem | 1979 |
3 other studies available for hexestrol and Fatty Liver
| Article | Year |
|---|---|
Steatohepatitis-inducing drugs trigger cytokeratin cross-links in hepatocytes. Possible contribution to Mallory-Denk body formation.
Topics: Amiodarone; Animals; Calcium; Fatty Liver; GTP-Binding Proteins; Hepatocytes; Hexestrol; Inclusion B | 2008 |
Steatohepatitis-inducing drugs cause mitochondrial dysfunction and lipid peroxidation in rat hepatocytes.
Topics: Animals; Cells, Cultured; Chemical and Drug Induced Liver Injury; Fatty Liver; Hexestrol; Humans; Li | 1998 |
Metabolic basis of diethylaminoethoxyhexestrol-induced phospholipid fatty liver.
Topics: Animals; Fatty Liver; Hexestrol; Lysosomes; Male; Phospholipases; Phospholipases A; Phospholipases A | 1987 |