Compounds > hexestrol
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hexestrol and Breast Cancer

hexestrol has been researched along with Breast Cancer in 35 studies

Research Excerpts

ExcerptRelevanceReference
"Twenty five cases of advanced postmenopausal breast cancer patients were treated with bisbromoacetyl hexestrol 3 CR and 5 PR were achieved."7.67Treatment of postmenopausal breast cancer with bisbromoacetyl hexestrol. ( He, G; Zhao, T, 1988)
"Twenty five cases of advanced postmenopausal breast cancer patients were treated with bisbromoacetyl hexestrol 3 CR and 5 PR were achieved."3.67Treatment of postmenopausal breast cancer with bisbromoacetyl hexestrol. ( He, G; Zhao, T, 1988)
"Seventy patients with breast cancer (stage IIIb--IV) were randomized by an "envelope" method into 2 groups, each including 35 persons."2.64[Combined drug treatment of far-advanced forms of breast cancer]. ( Borisov, AI, 1978)
"Studies performed in MCF-7 human breast cancer cells, which contain endogenous ER, yielded similar bioactivity profiles for the E-4-E bivalent inhibitory ligands, showing them to be effective estrogen antagonists, when using either induction of progesterone receptor or (ERE)2-TATA-CAT transcriptional activation as the endpoint."1.29Bivalent ligands as probes of estrogen receptor action. ( Bergmann, KE; Carlson, KE; Katzenellenbogen, BS; Katzenellenbogen, JA; Wooge, CH, 1994)
"In T47D breast cancer cells, the NBD-progestin showed receptor-mediated uptake and nuclear localization."1.28Receptor binding of NBD-labeled fluorescent estrogens and progestins in whole cells and cell-free preparations. ( Carlson, KE; Coppey, M; Katzenellenbogen, JA; Magdelenat, H, 1989)
"Estrogen receptors (ER) in breast cancer patients were determined histologically with estradiol-BSA-FITC and biochemically both by sucrose density gradient and dextran coated charcoal methods."1.27[Histochemical and biochemical assays of estrogen receptors in breast cancer and significance of endocrine therapy]. ( Tominaga, T, 1983)

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-199033 (94.29)18.7374
1990's2 (5.71)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
DaSilva, JN1
van Lier, JE1
Zablocki, JA1
Katzenellenbogen, JA5
Carlson, KE3
Norman, MJ1
Katzenellenbogen, BS2
Goswami, R1
Harsy, SG1
Heiman, DF2
von Angerer, E2
Egginger, G1
Kranzfelder, G3
Bernhauer, H1
Schönenberger, H2
Senderoff, SG1
Neeley, RJ1
FOLCA, PJ1
GLASCOCK, RF1
IRVINE, WT1
VARGAS, L1
LUCCHINI, A1
ARRAZTOA, J1
DIETRICH, LS1
SPITALIER, JM1
ROUX, G1
DESGEORGE, Y1
FARCY, A1
MANNES, P1
MOENS, J1
LAGOVA, ND2
SAMOJLOV, VI1
BOURDIN, JS1
SARACINO, RT1
LILLE, I1
GABAY, F1
BELOVA, MG1
VALUJEVA, IM1
DYMARSKII, LIu1
DILMAN, VM1
BOGNIBOE, EA1
KURALASOV, AK1
Krohn, KA1
Castagnetta, L1
D'Agostino, C1
Lo Casto, M1
Traina, A1
Leake, RE1
Hartmann, RW3
Bogden, AE1
Tominaga, T1
Bergmann, KE1
Wooge, CH1
El'tsina, NV1
Borisov, AI1
Kubista, E1
Grünberger, W1
Wolf, G1
Coppey, M1
Magdelenat, H1
Zhao, T1
He, G1
Sinchai, T1
Sanchakova, AV1
Alferova, MS1
McGuire, WL1
Monfardini, S1
Cunsolo, A1
Bonadonna, G1
Di Pietro, S1
Olinia, AIa1
Bankl, H1
Geyer, G1
Jesserer, H1
Keibl, E1
Kucsko, L1
Kotzaurek, R1
Studer, H1
Dolder, M1

Reviews

3 reviews available for hexestrol and Breast Cancer

ArticleYear
The search for a gamma-emitting estrogenic ligand.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1980, Volume: 21, Issue:6

    Topics: Animals; Breast Neoplasms; Bromine; Female; Fluorine; Hexestrol; Humans; Iodine Radioisotopes; Male;

1980
[Estrogen receptors in human and animal mammary gland tumors].
    Voprosy onkologii, 1975, Volume: 21, Issue:5

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenalectomy; Animals; Biological Transport, Active; Breast Neopl

1975
A new approach for selecting patients with metastatic breast cancer for hypophysectomy.
    Clinical neurosurgery, 1974, Volume: 21

    Topics: Age Factors; Androgens; Animals; Benz(a)Anthracenes; Binding Sites; Breast; Breast Neoplasms; Castra

1974

Trials

2 trials available for hexestrol and Breast Cancer

ArticleYear
[Combined drug treatment of far-advanced forms of breast cancer].
    Voprosy onkologii, 1978, Volume: 24, Issue:12

    Topics: Antineoplastic Agents; Breast Neoplasms; Castration; Clinical Trials as Topic; Cyclophosphamide; Dru

1978
[The effect of hexestrol on the breast in climacteric women (author's transl)].
    Wiener medizinische Wochenschrift (1946), 1979, Jan-15, Volume: 129, Issue:1

    Topics: Adult; Blood Coagulation; Breast; Breast Neoplasms; Climacteric; Female; Hematologic Tests; Hexestro

1979

Other Studies

30 other studies available for hexestrol and Breast Cancer

ArticleYear
Synthesis and structure-affinity of a series of 7 alpha-undecylestradiol derivatives: a potential vector for therapy and imaging of estrogen-receptor-positive cancers.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:1

    Topics: Animals; Binding, Competitive; Breast Neoplasms; Cattle; Chemical Phenomena; Chemistry; Estradiol; F

1990
Estrogenic affinity labels: synthesis, irreversible receptor binding, and bioactivity of aziridine-substituted hexestrol derivatives.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:5

    Topics: Affinity Labels; Animals; Aziridines; Azirines; Binding, Competitive; Breast Neoplasms; Cell Divisio

1987
Estrogen receptor based imaging agents. 2. Synthesis and receptor binding affinity of side-chain halogenated hexestrol derivatives.
    Journal of medicinal chemistry, 1980, Volume: 23, Issue:9

    Topics: Animals; Breast Neoplasms; Female; Hexestrol; In Vitro Techniques; Radionuclide Imaging; Receptors,

1980
N,N'-Dialkyl-1,2-bis(hydroxyphenyl)ethylenediamines and N,N-dialkyl-4,5-bis(4-hydroxyphenyl)imidazolidines: syntheses and evaluation of their mammary tumor inhibiting activity.
    Journal of medicinal chemistry, 1982, Volume: 25, Issue:7

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Division; C

1982
Estrogen receptor based imaging agents. 1. Synthesis and receptor binding affinity of some aromatic and D-ring halogenated estrogens.
    Journal of medicinal chemistry, 1980, Volume: 23, Issue:9

    Topics: Animals; Breast Neoplasms; Estradiol Congeners; Estrogens, Non-Steroidal; Female; In Vitro Technique

1980
Studies with tritium-labelled hexoestrol in advanced breast cancer. Comparison of tissue accumulation of hexoestrol with response to bilateral adrenalectomy and oophorectomy.
    Lancet (London, England), 1961, Oct-07, Volume: 2, Issue:7206

    Topics: Adrenalectomy; Breast; Breast Neoplasms; Castration; Estrogens; Female; Hexestrol; Humans; Ovariecto

1961
[Regression of metastases from breast cancer induced by hexestrol].
    Revista medica de Chile, 1962, Volume: 90

    Topics: Breast; Breast Neoplasms; Hexestrol; Humans; Stilbenes

1962
AUGMENTATION OF 6-AMINONICOTINAMIDE ANTAGONISM OF TUMOR GROWTH BY COMPOUNDS WITH ESTROGENIC ACTIVITY.
    Cancer research, 1964, Volume: 24

    Topics: 6-Aminonicotinamide; Adenocarcinoma; Animals; Antineoplastic Agents; Breast Neoplasms; Cortisone; Di

1964
[CYCLIC ESTROGEN THERAPY OF BREAST CANCER IN OLDER WOMEN].
    Marseille medical, 1963, Volume: 100

    Topics: Antineoplastic Agents; Breast Neoplasms; Estrogens; Geriatrics; Hexestrol; Humans; Neoplasms; Surgic

1963
[HORMONAL AND CHEMICAL TREATMENT OF BREAST CANCER METASTASES].
    Le Poumon et le coeur, 1964, Volume: 20

    Topics: Antineoplastic Agents; Breast Neoplasms; Castration; Diethylstilbestrol; Estrogens; Ethinyl Estradio

1964
MECHANISM OF ANTITUMOUR ACTION OF OESTROGENS ON MAMMARY CANCER.
    Acta - Unio Internationalis Contra Cancrum, 1964, Volume: 20

    Topics: Animals; Breast Neoplasms; Estrogens; Follicle Stimulating Hormone; Hexestrol; Humans; Hyperplasia;

1964
[STUDY OF VARIATIONS IN THE COMPLEMENT LEVEL IN THE COURSE OF CANCER CHEMOTHERAPY].
    Acta - Unio Internationalis Contra Cancrum, 1964, Volume: 20

    Topics: Animals; Breast Neoplasms; Bronchial Neoplasms; Complement System Proteins; Cyclophosphamide; Dexame

1964
INFLUENCE OF BOTH HORMONAL AND ALKYLATING DRUGS ON FOLLICLE-STIMULATION FUNCTION OF THE PITUITARY.
    Acta - Unio Internationalis Contra Cancrum, 1964, Volume: 20

    Topics: Breast Neoplasms; Dysgerminoma; Female; Follicle Stimulating Hormone; Hexestrol; Humans; Melphalan;

1964
[SUCCESSFUL TREATMENT OF SEVERE HYPERCALCEMIA IN A PATIENT WITH MULTIPLE BONE METASTASES FROM CANCER OF THE MAMMARY GLANDS].
    Klinicheskaia meditsina, 1964, Volume: 42

    Topics: Bone Neoplasms; Breast Neoplasms; Citrates; Cortisone; Drug Therapy; Hexestrol; Humans; Hypercalcemi

1964
[ON THE MECHANISM OF THE ANTINEOPLASTIC ACTION OF THIO-TEPA IN COMBINATION WITH ESTROGENS IN MAMMARY GLAND CANCER IN RATS].
    Biulleten' eksperimental'noi biologii i meditsiny, 1964, Volume: 57

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Estrogens; Follicle Stimulating Hormone; Hexestrol

1964
[ON CAUSES OF THE DEVELOPMENT OF RECURRENCE OF MAMMARY CANCER UNDER CONDITIONS OF HORMONE THERAPY].
    Biulleten' eksperimental'noi biologii i meditsiny, 1964, Volume: 57

    Topics: Animals; Breast Neoplasms; Follicle Stimulating Hormone; Hexestrol; Humans; Mammary Neoplasms, Anima

1964
Breast cancer: a comparison of response to endocrine therapy and oestrogen excretion patterns including unusual metabolites.
    British journal of cancer, 1981, Volume: 44, Issue:5

    Topics: Aged; Breast Neoplasms; Diethylstilbestrol; Estriol; Estrogens; Female; Hexestrol; Humans; Middle Ag

1981
3,4-bis(3'-hydroxyphenyl)hexane--a new mammary tumor-inhibiting compound.
    Journal of cancer research and clinical oncology, 1982, Volume: 103, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Breast Neoplasms; Castration; Cell

1982
[Histochemical and biochemical assays of estrogen receptors in breast cancer and significance of endocrine therapy].
    Gan no rinsho. Japan journal of cancer clinics, 1983, Volume: 29, Issue:6

    Topics: Antineoplastic Agents; Breast Neoplasms; Female; Hexestrol; Histocytochemistry; Humans; Medroxyproge

1983
Screening procedure for the development of mammary tumour-inhibiting anti-oestrogens.
    Cancer treatment reviews, 1984, Volume: 11 Suppl A

    Topics: Animals; Breast Neoplasms; Cattle; Chickens; Drug Evaluation, Preclinical; Estrogen Antagonists; Fem

1984
Bivalent ligands as probes of estrogen receptor action.
    The Journal of steroid biochemistry and molecular biology, 1994, Volume: 49, Issue:2-3

    Topics: Animals; Binding Sites; Binding, Competitive; Breast Neoplasms; CHO Cells; Cricetinae; Estradiol; He

1994
Receptor binding of NBD-labeled fluorescent estrogens and progestins in whole cells and cell-free preparations.
    Journal of steroid biochemistry, 1989, Volume: 32, Issue:3

    Topics: Affinity Labels; Binding, Competitive; Breast Neoplasms; Cell Line; Cell Nucleus; Cytoplasm; Estradi

1989
Treatment of postmenopausal breast cancer with bisbromoacetyl hexestrol.
    Tumori, 1988, Dec-31, Volume: 74, Issue:6

    Topics: Aged; Antineoplastic Agents; Breast Neoplasms; Female; Hexestrol; Humans; Menopause; Middle Aged

1988
Anti-proliferative effects of 1,2-diphenylethane oestrogens and anti-oestrogens on human breast cancer cells.
    Journal of cancer research and clinical oncology, 1985, Volume: 110, Issue:1

    Topics: Breast Neoplasms; Cell Division; Cell Line; Dose-Response Relationship, Drug; Estrogen Antagonists;

1985
[Combined and complex treatment of diffuse-infiltrative forms of breast cancer].
    Voprosy onkologii, 1972, Volume: 18, Issue:4

    Topics: Adenocarcinoma, Bronchiolo-Alveolar; Adenocarcinoma, Mucinous; Adenocarcinoma, Scirrhous; Adult; Age

1972
[Late results of breast cancer treatment].
    Voprosy onkologii, 1973, Volume: 19, Issue:10

    Topics: Adenocarcinoma; Adenocarcinoma, Scirrhous; Adult; Breast Neoplasms; Carcinoma; Carcinoma, Intraducta

1973
[Use of hexoestrol in the therapy of advanced breast carcinoma].
    Minerva medica, 1970, May-05, Volume: 61, Issue:36

    Topics: Age Factors; Antineoplastic Agents; Breast Neoplasms; Carcinoma; Diethylstilbestrol; Female; Hexestr

1970
[Excretion of hormones in patients with cancer of the breast after hormone loading with synestrol and cortisone].
    Klinika i lechenie zlokachestvennykh novoobrazovanii, 1968, Volume: 11

    Topics: Breast Neoplasms; Cortisone; Estrogens; Female; Glucocorticoids; Hexestrol; Humans; Pregnanediol

1968
[Hypercalcemic crisis and hypocalcemic tetany during treatment with sex hormones in a case of breast carcinoma with metastasis in the skeleton and parathyroid glands].
    Wiener klinische Wochenschrift, 1966, Oct-14, Volume: 78, Issue:41

    Topics: Blood Chemical Analysis; Blood Sedimentation; Bone Marrow Examination; Bone Neoplasms; Breast Neopla

1966
[Therapy of the metastasizing mammary carcinoma].
    Schweizerische medizinische Wochenschrift, 1966, Feb-26, Volume: 96, Issue:8

    Topics: Adult; Breast Neoplasms; Diethylstilbestrol; Estradiol; Estrogens; Female; Hexestrol; Humans; Hypoph

1966