Page last updated: 2024-10-28

hexamethylene bisacetamide and Melanoma

hexamethylene bisacetamide has been researched along with Melanoma in 5 studies

N,N'-diacetyl-1,6-diaminohexane: chemical name obtained from Acta Biol Hung 1990;41(1-3):199-208

Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (80.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Vijayasaradhi, S1
Doskoch, PM1
Wolchok, J1
Houghton, AN1
Sturm, RA1
O'Sullivan, BJ1
Thomson, JA1
Jamshidi, N1
Pedley, J1
Parsons, PG1
Edward, M1
Godden, JL1
Alexander, CL1
MacKie, RM1
Fang, D2
Setaluri, V2
Hallman, J1
Sangha, N1
Kute, TE1
Hammarback, JA1
White, WL1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Phase I Study of gp75 DNA Vaccine in Patients With AJCC Stage III and IV Melanoma[NCT00034554]Phase 131 participants (Actual)Interventional2002-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

5 other studies available for hexamethylene bisacetamide and Melanoma

ArticleYear
Melanocyte differentiation marker gp75, the brown locus protein, can be regulated independently of tyrosinase and pigmentation.
    The Journal of investigative dermatology, 1995, Volume: 105, Issue:1

    Topics: Acetamides; Dendrites; Down-Regulation; Humans; Melanoma; Membrane Glycoproteins; Monophenol Monooxy

1995
Expression studies of pigmentation and POU-domain genes in human melanoma cells.
    Pigment cell research, 1994, Volume: 7, Issue:4

    Topics: Acetamides; Base Sequence; Binding Sites; Dimethyl Sulfoxide; DNA; DNA-Binding Proteins; Gene Expres

1994
Effect of retinoic acid on melanoma cell-derived factor stimulation of fibroblast glycosaminoglycan synthesis.
    Melanoma research, 1997, Volume: 7, Issue:3

    Topics: Acetamides; Adult; Antineoplastic Agents; Butyrates; Butyric Acid; Cell Count; Cell Differentiation;

1997
Role of microphthalmia transcription factor in regulation of melanocyte differentiation marker TRP-1.
    Biochemical and biophysical research communications, 1999, Mar-24, Volume: 256, Issue:3

    Topics: Acetamides; Blotting, Western; Cell Nucleus; Cell Size; Cholera Toxin; Cycloheximide; Dactinomycin;

1999
Expression of microtubule-associated protein 2 in benign and malignant melanocytes: implications for differentiation and progression of cutaneous melanoma.
    The American journal of pathology, 2001, Volume: 158, Issue:6

    Topics: Acetamides; Biomarkers; Cell Differentiation; Cell Line; Cyclic AMP; Disease Progression; Gene Expre

2001