hexamethylene bisacetamide has been researched along with Leukopenia in 2 studies
N,N'-diacetyl-1,6-diaminohexane: chemical name obtained from Acta Biol Hung 1990;41(1-3):199-208
Leukopenia: A decrease in the number of LEUKOCYTES in a blood sample below the normal range (LEUKOCYTE COUNT less than 4000).
| Excerpt | Relevance | Reference |
|---|---|---|
| "The efficacy of hexamethylene bisacetamide (HMBA), a potent polar-planar solvent which is capable of differentiating leukemias and solid tumors in vitro at clinically achievable concentrations, was studied in 16 patients with severe myelodysplastic syndromes (MDS)." | 3.68 | Hexamethylene bisacetamide in myelodysplastic syndrome: effect of five-day exposure to maximal therapeutic concentrations. ( Auerbach, M; Conley, BA; Donehower, RC; Jones, RJ; Rowinsky, EK; Spivak, JL, 1992) |
| "Hexamethylene bisacetamide was administered as a 5% (w/v) solution via a nasogastric or gastrostomy tube every 4 h for 5 days, followed in 21 days by a 5-day continuous i." | 2.67 | Phase I bioavailability and pharmacokinetic study of hexamethylene bisacetamide (NSC 95580) administered via nasogastric tube. ( Chun, HG; Kelley, JA; Leyland-Jones, B; Lombardo, FA; Roth, JS; Ward, FT; Weiss, RB, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rowinsky, EK | 1 |
| Conley, BA | 1 |
| Jones, RJ | 1 |
| Spivak, JL | 1 |
| Auerbach, M | 1 |
| Donehower, RC | 1 |
| Ward, FT | 1 |
| Kelley, JA | 1 |
| Roth, JS | 1 |
| Lombardo, FA | 1 |
| Weiss, RB | 1 |
| Leyland-Jones, B | 1 |
| Chun, HG | 1 |
1 trial available for hexamethylene bisacetamide and Leukopenia
| Article | Year |
|---|---|
Phase I bioavailability and pharmacokinetic study of hexamethylene bisacetamide (NSC 95580) administered via nasogastric tube.
Topics: Acetamides; Adult; Aged; Biological Availability; Confusion; Drug Evaluation; Female; Gastrointestin | 1991 |
1 other study available for hexamethylene bisacetamide and Leukopenia
| Article | Year |
|---|---|
Hexamethylene bisacetamide in myelodysplastic syndrome: effect of five-day exposure to maximal therapeutic concentrations.
Topics: Acetamides; Adult; Aged; Algorithms; Cell Division; Depression, Chemical; Drug Administration Schedu | 1992 |