hexamethylene bisacetamide has been researched along with Leukocytopenia in 2 studies
N,N'-diacetyl-1,6-diaminohexane: chemical name obtained from Acta Biol Hung 1990;41(1-3):199-208
Excerpt | Relevance | Reference |
---|---|---|
"The efficacy of hexamethylene bisacetamide (HMBA), a potent polar-planar solvent which is capable of differentiating leukemias and solid tumors in vitro at clinically achievable concentrations, was studied in 16 patients with severe myelodysplastic syndromes (MDS)." | 3.68 | Hexamethylene bisacetamide in myelodysplastic syndrome: effect of five-day exposure to maximal therapeutic concentrations. ( Auerbach, M; Conley, BA; Donehower, RC; Jones, RJ; Rowinsky, EK; Spivak, JL, 1992) |
"Hexamethylene bisacetamide was administered as a 5% (w/v) solution via a nasogastric or gastrostomy tube every 4 h for 5 days, followed in 21 days by a 5-day continuous i." | 2.67 | Phase I bioavailability and pharmacokinetic study of hexamethylene bisacetamide (NSC 95580) administered via nasogastric tube. ( Chun, HG; Kelley, JA; Leyland-Jones, B; Lombardo, FA; Roth, JS; Ward, FT; Weiss, RB, 1991) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 2 (100.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Rowinsky, EK | 1 |
Conley, BA | 1 |
Jones, RJ | 1 |
Spivak, JL | 1 |
Auerbach, M | 1 |
Donehower, RC | 1 |
Ward, FT | 1 |
Kelley, JA | 1 |
Roth, JS | 1 |
Lombardo, FA | 1 |
Weiss, RB | 1 |
Leyland-Jones, B | 1 |
Chun, HG | 1 |
1 trial available for hexamethylene bisacetamide and Leukocytopenia
Article | Year |
---|---|
Phase I bioavailability and pharmacokinetic study of hexamethylene bisacetamide (NSC 95580) administered via nasogastric tube.
Topics: Acetamides; Adult; Aged; Biological Availability; Confusion; Drug Evaluation; Female; Gastrointestin | 1991 |
1 other study available for hexamethylene bisacetamide and Leukocytopenia
Article | Year |
---|---|
Hexamethylene bisacetamide in myelodysplastic syndrome: effect of five-day exposure to maximal therapeutic concentrations.
Topics: Acetamides; Adult; Aged; Algorithms; Cell Division; Depression, Chemical; Drug Administration Schedu | 1992 |