hexamethylene bisacetamide has been researched along with Leukemia, Erythroblastic, Acute in 206 studies
N,N'-diacetyl-1,6-diaminohexane: chemical name obtained from Acta Biol Hung 1990;41(1-3):199-208
Leukemia, Erythroblastic, Acute: A myeloproliferative disorder characterized by neoplastic proliferation of erythroblastic and myeloblastic elements with atypical erythroblasts and myeloblasts in the peripheral blood.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The JOK-1 hairy cell leukemia derived cell line has been propagated as a subcutaneous tumor in nude mice." | 5.27 | Effect of dimethylsulfoxide and hexamethylene bisacetamide on the JOK-1 hairy cell leukemia derived cell line propagated in the nude mouse. ( Barth, RF; Hooper, WC; Houchens, DP; Nines, R, 1987) |
| "With virus-transformed murine erythroleukemia cells as a model, HMBA was shown to cause these cells to arrest in G1 phase and express globin genes." | 2.39 | Inducing differentiation of transformed cells with hybrid polar compounds: a cell cycle-dependent process. ( Kiyokawa, H; Marks, PA; Richon, VM; Rifkind, RA, 1994) |
| "With virus-transformed murine erythroleukemia cells as a model, HMBA was shown to cause these cells to arrest in G1 phase and express globin genes." | 2.39 | Induced differentiation, the cell cycle, and the treatment of cancer. ( Marks, PA; Richon, VM; Rifkind, RA, 1996) |
| "Friend murine erythroleukemia cell lines derive from erythroblasts transformed with the Friend complex where the spleen-focus forming virus integrated in the vicinity of the Sfpi-1 locus." | 1.35 | PU.1 is dispensable to block erythroid differentiation in Friend erythroleukemia cells. ( Fernández-Nestosa, MJ; Hernández, P; Krimer, DB; Schvartzman, JB, 2008) |
| "Murine erythroleukemia (MEL) cells are transformed erythroid precursors that are arrested in an immature and proliferating state." | 1.34 | Proteomic analysis of erythroid differentiation induced by hexamethylene bisacetamide in murine erythroleukemia cells. ( Cmejla, R; Cmejlova, J; Man, P; Myslivcova, D; Petrak, J; Vyoral, D, 2007) |
| "Murine erythroleukemia (MEL) cells are widely used to study erythroid differentiation thanks to their ability to terminally differentiate in vitro in response to chemical induction." | 1.33 | Microarray profiling of genes differentially expressed during erythroid differentiation of murine erythroleukemia cells. ( Cho, YS; Heo, HS; Kim, CG; Kim, JH; Kim, SH; Lee, YJ, 2005) |
| "Murine erythroleukemia (MEL) cells undergo erythroid differentiation in vitro when treated with hexamethylene bisacetamide (HMBA)." | 1.32 | Differential expression of Ran GTPase during HMBA-induced differentiation in murine erythroleukemia cells. ( del Mazo, J; García-Sacristán, A; Hernández, P; Krimer, DB; López-Fernández, LA; Párraga, M; Schvartzman, JB; Vanegas, N, 2003) |
| "Human erythroleukemia cell K562, murine erythroleukemia cell (MEL) and its sub-line MEL DS19 were used as target cells to select a cell line which is the most sensitive to HMBA, then analyzed the activity of inducing differentiation of two new designed HMBA derivatives: HMBPA [hexamethylenebi (3-pyridin) amide] and Co-HDTA (ethylenediaminetetra acetic acid cobalt) using cell biology, cytochemical and molecular biology techniques." | 1.31 | New designed HMBA agents as inducers of erythroleukemia cell differentiation. ( Wang, H; Zhang, J; Zhang, S; Zhou, J, 2002) |
| "Two variants of Friend erythroleukemia cells were treated with hexamethylene bisacetamide (HMBA) to induce differentiation: 1) MEL, which exhibit the normal phenotype and are susceptible to differentiation; and 2) the resistant R1 cells." | 1.31 | Structural characterization of erythroid and megakaryocytic differentiation in Friend erythroleukemia cells. ( Heller, A; Hyman, T; Malik, Z; Rothmann, C; Salzberg, S, 2001) |
| "Friend murine erythroleukemia (MEL) cells are transformed erythroid precursors that are held in an immature and proliferating state but can be induced to differentiate in vivo by treatment with a variety of chemical agents such as N, N-hexamethylene bisacetamide (HMBA)." | 1.31 | A Myb dependent pathway maintains Friend murine erythroleukemia cells in an immature and proliferating state. ( Bender, TP; Chen, J; Kremer, CS, 2002) |
| "Irreversible damage to Friend's erythroleukemia cells was caused by induction of endogenous heme biosynthesis with the differentiating agent N,N'-hexamethylene bisacetamide followed by a 30-min exposure to 0." | 1.30 | Severe energy impairment consequent to inactivation of mitochondrial ATP synthase as an early event in cell death: a mechanism for the selective sensitivity to H2O2 of differentiating erythroleukemia cells. ( Comelli, M; Londero, D; Mavelli, I, 1998) |
| "We show here that murine erythroleukemia (MEL) cells, following induction with hexamethylene bisacetamide, accumulate high mobility group (HMG)1 protein onto the external surface of the cell in a membrane-associated form detectable by immunostaining with a specific anti-HMG1 protein antibody." | 1.30 | Secretion and binding of HMG1 protein to the external surface of the membrane are required for murine erythroleukemia cell differentiation. ( Melloni, E; Passalacqua, M; Patrone, M; Pontremoli, S; Sparatore, B; Zicca, A, 1997) |
| "Murine erythroleukemia cells developed for resistance to SAHA are cross-resistant to trichostatin A, a known deacetylase inhibitor and differentiation inducer, but are not cross-resistant to HMBA." | 1.30 | A class of hybrid polar inducers of transformed cell differentiation inhibits histone deacetylases. ( Breslow, R; Emiliani, S; Marks, PA; Richon, VM; Rifkind, RA; Verdin, E; Webb, Y, 1998) |
| "Mouse erythroleukemia (MEL) cell erythroid differentiation induced by dimethyl sulfoxide or hexamethylene bisacetamide (HMBA) is accompanied by the production of hemoglobin, terminal cell division and decreases in lactate production and fructose 2,6-bisphosphate levels." | 1.30 | Dephosphorylation of Vav is associated with the induction of mouse erythroleukemia cell differentiation: effects of orthovanadate and levamisole. ( Scher, BM; Scher, W; Waxman, S; Wei, XJ, 1998) |
| "Differentiation of murine erythroleukemia cells induced by hexamethylene bisacetamide (HMBA) is associated with accumulation of underphosphorylated retinoblastoma protein (pRB) and an increase in retinoblastoma (RB) gene expression." | 1.29 | Suppression of cyclin-dependent kinase 4 during induced differentiation of erythroleukemia cells. ( Kiyokawa, H; Marks, PA; Richon, VM; Rifkind, RA, 1994) |
| "Friend murine erythroleukemia cells (MELCs) have been reevaluated in terms of their nature and potential pathways of differentiation." | 1.29 | Identification and conditions for selective expression of megakaryocytic markers in Friend erythroleukemia cells. ( Burstein, SA; Caporale, R; Mocali, A; Paoletti, F; Vannucchi, AM, 1995) |
| "Murine erythroleukemia cells (MELC) have served as a model for examining the regulation of erythroid differentiation." | 1.29 | Calcium influx in induced differentiation of murine erythroleukemia cells. ( Gillo, B; Ma, YS; Marks, AR, 1993) |
| "Calpain has been identified as the intracellular proteinase that catalyzes the selective down-regulation of protein kinase C (PKC) isoforms, occurring in the early stages of commitment to terminal erythroid differentiation of murine erythroleukemia (MEL) cells induced by hexamethylenebisacetamide." | 1.29 | Modulation of the intracellular Ca(2+)-dependent proteolytic system is critically correlated with the kinetics of differentiation of murine erythroleukemia cells. ( Melloni, E; Passalacqua, M; Patrone, M; Pessino, A; Pontremoli, S; Sparatore, B, 1994) |
| " Daunomycin proved to be more toxic to differentiated Friend cells than to their undifferentiated counterparts." | 1.29 | Enhancement of daunomycin toxicity by the differentiation inducer hexamethylene bisacetamide in erythroleukemia cells. ( Marcocci, L; Mavelli, I; Mondovì, B; Pedersen, JZ; Pietrangeli, P; Steinkühler, C, 1994) |
| "G1 arrest of murine erythroleukemia cells induced by aphidicolin or deferoxamine is not associated with accumulation of under-phosphorylated retinoblastoma protein, suppression of cyclin A protein, or commitment of cells to terminal differentiation." | 1.29 | Hexamethylenebisacetamide-induced erythroleukemia cell differentiation involves modulation of events required for cell cycle progression through G1. ( Kiyokawa, H; Marks, PA; Richon, VM; Rifkind, RA; Venta-Perez, G, 1993) |
| "Murine erythroleukemia cells rendered deficient in cAMP-dependent protein kinase (A-kinase) activity by gene transfection are severely impaired in hexamethylene bisacetamide (HMBA)-induced differentiation (Pilz, R." | 1.29 | Impaired erythroid-specific gene expression in cAMP-dependent protein kinase-deficient murine erythroleukemia cells. ( Pilz, RB, 1993) |
| "The human erythroleukemia cell line K562 can be induced to differentiate along the erythroid and megakaryocytic lineages." | 1.29 | Induced myeloid differentiation of K562 cells with downregulation of erythroid and megakaryocytic transcription factors: a novel experimental model for hemopoietic lineage restriction. ( Begley, CG; DeLuca, E; Green, AR; Rockman, S, 1993) |
| "In murine erythroleukemia (MEL) cells the length of the latent period before the onset of hexamethylenebisacetamide induced terminal erythroid differentiation is inversely correlated to the intracellular level of delta-PKC." | 1.29 | Role of delta-PKC on the differentiation process of murine erythroleukemia cells. ( Melloni, E; Passalacqua, M; Patrone, M; Pessino, A; Pontremoli, S; Sparatore, B, 1993) |
| "Differentiation of murine erythroleukemia (MEL) cells induced by hexamethylene bisacetamide (HMBA) and DMSO was inhibited by several structurally unrelated nitric oxide (NO)-releasing agents and two membrane-permeable cGMP analogues." | 1.29 | Nitric oxide-releasing agents and cGMP analogues inhibit murine erythroleukemia cell differentiation and suppress erythroid-specific gene expression: correlation with decreased DNA binding of NF-E2 and altered c-myb mRNA expression. ( Boss, GR; Pascual, FE; Pilz, RB; Suhasini, M, 1995) |
| "Hexamethylene bisacetamide (HMBA) is a most effective compound as an inducer of MELC differentiation." | 1.28 | Induced differentiation of murine erythroleukemia cells (MELC) by polar compounds: marked increased sensitivity of vincristine resistant MELC. ( Jackson, J; Marks, PA; Michaeli, J; Richon, VM; Rifkind, RA, 1989) |
| "The induction of murine erythroleukemia cells (MELC) to terminal differentiation by hexamethylene bisacetamide (HMBA) is accompanied by changes in the levels of c-myb and c-myc mRNA, and in p53 protein levels." | 1.28 | Modulation of the c-myb, c-myc and p53 mRNA and protein levels during induced murine erythroleukemia cell differentiation. ( Marks, PA; Ramsay, RG; Richon, VM; Rifkind, RA, 1989) |
| "Vincristine-resistant murine erythroleukemia cells also are shown to have marked increased sensitivity to these hybrid polar/apolar compounds." | 1.28 | Polar/apolar chemical inducers of differentiation of transformed cells: strategies to improve therapeutic potential. ( Breslow, R; Marks, PA; Ngo, L; Rifkind, RA; Singh, R, 1989) |
| "Murine Friend-derived erythroleukemia cells (MEL) are generally believed to be unipotential progenitors inducible to terminal erythroid differentiation." | 1.28 | Constitutive expression of a megakaryocytic functional property by murine erythroleukemia (Friend) cells: the incorporation of serotonin. ( Bacci, P; Ferrini, PR; Grossi, A; Paoletti, F; Rafanelli, D; Vannucchi, AM, 1992) |
| "coli (Ecogpt) into mouse erythroleukemia (MEL) cells by protoplast fusion." | 1.28 | Inhibition of expression of a mouse alpha-globin gene by plasmids that include antisense oligonucleotides. ( Gachelin, G; Gao, H; Hou, DX; Kitabayashi, I; Nishikura, K; Tang, X; Yokoyama, K, 1992) |
| "Following treatment of mouse erythroleukemia (MEL) cells with dimethyl sulfoxide and other typical erythroid inducing agents, the profile of cellular phosphotyrosine-containing proteins was drastically altered." | 1.28 | Alteration of phosphotyrosine-containing proteins at the early stage of erythroid differentiation of mouse erythroleukemia (MEL) cells. ( Kume, T; Oishi, M; Watanabe, T, 1992) |
| "Friend erythroleukemia cells treated with hexamethylene bisacetamide differentiate in a similar manner, while agents such as hemin apparently induce differentiation without limiting cell proliferation." | 1.28 | Proliferation is required for induction of terminal differentiation of Friend erythroleukemia cells. ( Hill, SM; Jeter, JR; Spriggs, LL, 1992) |
| "The induction of murine erythroleukemia cells (MELC; DS19/Sc9) to terminal differentiation by hexamethylenebisacetamide (HMBA) is characterized by a latent period of 10-12 hr before onset of commitment to terminal-cell division and increased transcription of globin genes." | 1.28 | Characteristics of erythroleukemia cells selected for vincristine resistance that have accelerated inducer-mediated differentiation. ( Kiyokawa, H; Leng, L; Marks, PA; Ngo, L; Richon, VM; Rifkind, RA; Weich, N, 1991) |
| "Nuclear matrix isolated from murine erythroleukemia cells (Friend cells) has been phosphorylated with gamma 32P-ATP and purified protein kinase C in order to identify specific nuclear substrates for the enzyme." | 1.28 | In vitro phosphorylation of lamin B by protein kinase C in friend erythroleukemia. Effect of chemically induced differentiation. ( Bertagnolo, V; Billi, AM; Capitani, S; Manzoli, FA; Matteucci, A; Previati, M, 1991) |
| "Hexamethylene bisacetamide (HMBA) is a potent inducer of differentiation of murine erythroleukemia cells (MELC)." | 1.28 | Conversion of differentiation inducer resistance to differentiation inducer sensitivity in erythroleukemia cells. ( Chen, ZX; Lebedev, YB; Marks, PA; Michaeli, J; Richon, VM; Rifkind, RA, 1990) |
| "In mouse erythroleukemia cells (MELCs), this effect is detected within 1 hr of exposure of the cells to inducer before the endogenous mouse globin genes are induced." | 1.28 | Induction by HMBA and DMSO of genes introduced into mouse erythroleukemia and other cell lines by transient transfection. ( Campbell, PL; Jones, RW; Kulozik, AE; Woodham, JP, 1990) |
| "Murine erythroleukemia cells contain a single type of calpain classified, on the basis of its calcium requirement, as a type I proteinase." | 1.28 | Murine erythroleukemia cell differentiation: possible involvement of a calcium dependent neutral proteinase. ( Passalacqua, M; Patrone, M; Salamino, F; Sparatore, B; Viotti, PL, 1990) |
| "We find that induction of mouse erythroleukemia cell differentiation with either dimethylsulfoxide (DMSO) or hexamethylene bisacetamide (HMBA) leads to increased expression of Rb mRNA." | 1.28 | Increased retinoblastoma gene expression is associated with late stages of differentiation in many different cell types. ( Cole, MD; Coppola, JA; Lewis, BA, 1990) |
| "Induction of differentiation in murine erythroleukemia cells (MELCs) involves a protein kinase C (PKC)-mediated step." | 1.28 | Introduction of the beta isozyme of protein kinase C accelerates induced differentiation of murine erythroleukemia cells. ( Grossi, F; Marks, PA; Melloni, E; Patrone, M; Pontremoli, S; Rifkind, RA; Sparatore, B, 1990) |
| "Murine erythroleukemia cells (MELC) are transformed cells that can be induced to differentiate by a variety of agents, such as hexamethylenebisacetamide (HMBA) and dimethyl sulfoxide." | 1.27 | Inducer-mediated commitment of murine erythroleukemia cells to terminal cell division: the expression of commitment. ( Kaneda, T; Marks, PA; Murate, T; Rifkind, RA, 1984) |
| "When mouse erythroleukemia (MEL) cells were induced to differentiate by growth in the presence of dimethyl sulfoxide, hexamethylene bisacetamide (HMBA), or hemin, the apparent activity of DNA ligase extractable from inducer-treated cells decreased 70 to 80% when compared to untreated cells." | 1.27 | A possible effect of heme on the fate of DNA ligase activity extracted from differentiating mouse erythroleukemia cells. ( Scher, BM; Scher, W; Waxman, S, 1988) |
| "The state of DNA methylation in mouse erythroleukemia (MEL) cells has been analyzed in relation to commitment to differentiation in response to treatment with hexamethylenebisacetamide (HMBA)." | 1.27 | Relationship between transient DNA hypomethylation and erythroid differentiation of murine erythroleukemia cells. ( Agostini, S; Cantoni, GL; Gomi, T; Kafri, T; Levine, A; Razin, A, 1988) |
| "The proerythroblastoid Friend erythroleukemia cell (FELC) line, clone TR 19-9, was treated with 4 mM hexamethylene bisacetamide (HMBA) over a 6-day period." | 1.27 | Two-dimensional gel electrophoretic analysis of cytoplasmic proteins from Friend erythroleukemia cells chemically induced to undergo terminal erythroid differentiation. ( Mann, RC; Mansfield, BK; Selkirk, JK, 1988) |
| "Finally, in murine erythroleukemia cells an RNA-dependent RNA polymerase activity is detected by using poly(A) ." | 1.27 | Cytoplasmic synthesis of globin RNA in differentiated murine erythroleukemia cells: possible involvement of RNA-dependent RNA polymerase. ( Volloch, V, 1986) |
| "5, 11, and 22 mW/cm2 with a normalized specific absorption rate of 3." | 1.27 | Differentiation of murine erythroleukemic cells during exposure to microwave radiation. ( Brown, RF; Marshall, SV, 1986) |
| "The integrated proviral DNA in Friend erythroleukemia cells was examined by Southern hybridization with a cloned Friend virus (F-MuLV) probe at days 1 and 4 following inducer treatment, as well as on day 6 at which time the cells had remained for 48 h in inducer free medium." | 1.27 | Induction of differentiation in Friend erythroleukemia cells with dimethyl sulfoxide, hexamethylene bisacetamide and sodium butyrate is not accompanied by changes in proviral DNA or its expression. ( Brown, E; Friend, C; Zajac-Kaye, M, 1986) |
| "The JOK-1 hairy cell leukemia derived cell line has been propagated as a subcutaneous tumor in nude mice." | 1.27 | Effect of dimethylsulfoxide and hexamethylene bisacetamide on the JOK-1 hairy cell leukemia derived cell line propagated in the nude mouse. ( Barth, RF; Hooper, WC; Houchens, DP; Nines, R, 1987) |
| "Murine erythroleukemia cells (MELC) are virus-transformed erythroid precursors that appear to be blocked at an erythroid precursor stage comparable to the erythroid colony-forming unit (CFU-e)." | 1.27 | Erythroleukemia cells: variants inducible for hemoglobin synthesis without commitment to terminal cell division. ( Banks, J; Chen, Z; Marks, PA; Rifkind, RA, 1983) |
| "Friend erythroleukemia cells were induced to differentiate by dimethyl sulfoxide (DMSO) and hexamethylene-bis-acetamide (HBMA) in order to investigate whether their lipid characteristics, common to other systems of transformed cells, revert to a normal differentiation pattern." | 1.27 | Lipid changes associated with erythroid differentiation of Friend erythroleukemia cells. ( Arcangeli, A; Fallani, A; Ruggieri, S, 1987) |
| "During differentiation of murine erythroleukemia cells, adult beta-globin gene chromatin acquires site-specific, DNase I hypersensitivity and an increased sensitivity in the globin gene region toward micrococcal nuclease (MNase) digestion." | 1.27 | Sequential alterations in globin gene chromatin structure during erythroleukemia cell differentiation. ( Smith, RD; Yu, J, 1985) |
| "Friend erythroleukemia cells were induced to differentiate in a chemically defined medium in which bovine serum albumin was substituted for fetal calf serum." | 1.26 | Comparative study of two groups of inducers of Friend erythroleukemia cell differentiation in a chemically defined medium. ( Gazitt, Y, 1981) |
| "Friend erythroleukemia cells were induced to differentiate by hexamethylene bisacetamide, dimethyl sulfoxide, and dimethylformamide." | 1.26 | Inhibition of induced L-ornithine decarboxylase stimulation and erythrodifferentiation in Friend erythroleukemia cells by 2',5'-isoadenylate trimer core. ( Gazitt, Y, 1981) |
| "Murine erythroleukemia cells are induced to erythrodifferentiate by polar compounds such as dimethyl sulfoxide and hexamethylene bisacetamide as well as by fatty acids such as butyric acid and propionic acid." | 1.26 | Differential effects of chemical inducers on expression of beta globin genes in murine erythroleukemia cells. ( Bank, A; Marks, PA; Nudel, U; Rifkind, RA; Salmon, JE; Terada, M, 1977) |
| "Friend virus-transformed murine erythroleukemia cells express the program of erythropoietic differentiation under the influence of the previously described, potent inducing agent, hexamethylene bisacetamide." | 1.26 | Effect of hexamethylene bisacetamide on the commitment to differentiation of murine erythroleukemia cells. ( Fibach, E; Marks, PA; Reuben, RC; Rifkind, RA, 1977) |
| "Murine erythroleukemia cells (MELC) are induced to express erythroid differentiation when cultured with hexamethylene bisacetamide (HMBA)." | 1.26 | Stability of alpha and beta globin messenger RNA during induced differentiation of mouse erythroleukemia cells. ( Gambari, R; Marks, PA; Rifkind, RA, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 97 (47.09) | 18.7374 |
| 1990's | 90 (43.69) | 18.2507 |
| 2000's | 18 (8.74) | 29.6817 |
| 2010's | 1 (0.49) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chatzopoulou, M | 1 |
| Bonovolias, ID | 1 |
| Nicolaou, I | 1 |
| Demopoulos, VJ | 1 |
| Vizirianakis, IS | 1 |
| Tsiftsoglou, AS | 1 |
| Vanegas, N | 1 |
| García-Sacristán, A | 2 |
| López-Fernández, LA | 1 |
| Párraga, M | 1 |
| del Mazo, J | 1 |
| Hernández, P | 3 |
| Schvartzman, JB | 3 |
| Krimer, DB | 3 |
| Wang, H | 1 |
| Zhang, S | 1 |
| Zhou, J | 1 |
| Zhang, J | 1 |
| Sarg, B | 1 |
| Helliger, W | 2 |
| Talasz, H | 1 |
| Koutzamani, E | 1 |
| Lindner, HH | 1 |
| Bodalina, UM | 2 |
| Hammond, KD | 9 |
| Gilbert, DA | 4 |
| Fernández-Nestosa, MJ | 2 |
| Turano, M | 1 |
| Napolitano, G | 1 |
| Dulac, C | 1 |
| Majello, B | 1 |
| Bensaude, O | 1 |
| Lania, L | 1 |
| Heo, HS | 1 |
| Kim, JH | 1 |
| Lee, YJ | 1 |
| Kim, SH | 1 |
| Cho, YS | 1 |
| Kim, CG | 2 |
| Rajagopalan, V | 1 |
| Blankenship, J | 1 |
| Thomas, DW | 1 |
| Chen, J | 2 |
| Kremer, CS | 2 |
| Bender, TP | 3 |
| Petrak, J | 1 |
| Myslivcova, D | 1 |
| Man, P | 1 |
| Cmejlova, J | 1 |
| Cmejla, R | 1 |
| Vyoral, D | 1 |
| Gazitt, Y | 3 |
| Friend, C | 3 |
| Bertolini, L | 1 |
| Tsuei, D | 1 |
| Holland, JG | 1 |
| Osborne, HB | 9 |
| Bakke, AC | 1 |
| Yu, J | 2 |
| Murate, T | 3 |
| Kaneda, T | 2 |
| Rifkind, RA | 46 |
| Marks, PA | 45 |
| Tolberg, ME | 1 |
| Smith, SS | 1 |
| Ley, TJ | 1 |
| Chiang, YL | 1 |
| Haidaris, D | 1 |
| Anagnou, NP | 2 |
| Wilson, VL | 1 |
| Anderson, WF | 3 |
| Bin, X | 1 |
| DiLiberto, M | 1 |
| Sheffery, M | 7 |
| Ngai, J | 1 |
| Capetanaki, YG | 1 |
| Lazarides, E | 1 |
| Profous-Juchelka, HR | 1 |
| Reuben, RC | 4 |
| Chen, Z | 2 |
| Banks, J | 3 |
| Gambari, R | 4 |
| Corin, RE | 2 |
| Haspel, HC | 2 |
| Sonenberg, M | 2 |
| Chabanas, A | 3 |
| Grove, GW | 1 |
| Zweidler, A | 1 |
| Carpinelli, G | 1 |
| Podo, F | 1 |
| Di Vito, M | 1 |
| Proietti, E | 1 |
| Gessani, S | 1 |
| Belardelli, F | 1 |
| Epner, E | 1 |
| Chen, ZX | 3 |
| Giri, JG | 1 |
| Morioka, K | 1 |
| Tanaka, K | 2 |
| Ono, T | 1 |
| Hugues, B | 1 |
| Diacumakos, EG | 1 |
| Killos, L | 1 |
| Lee, L | 1 |
| Yamasaki, H | 2 |
| Drevon, C | 1 |
| Martel, N | 1 |
| Kume, T | 3 |
| Tsuneizumi, K | 2 |
| Watanabe, T | 6 |
| Thomas, ML | 1 |
| Oishi, M | 5 |
| Aroor, AR | 1 |
| Singh, LP | 1 |
| Wahba, AJ | 1 |
| Coccia, EM | 1 |
| Stellacci, E | 1 |
| Orsatti, R | 1 |
| Testa, U | 1 |
| Battistini, A | 1 |
| Delcros, JG | 1 |
| Schwartz, B | 1 |
| Clément, S | 1 |
| Basu, HS | 1 |
| Marton, LJ | 1 |
| Feuerstein, BG | 1 |
| Fuchs, O | 2 |
| Paoletti, F | 3 |
| Vannucchi, AM | 2 |
| Mocali, A | 2 |
| Caporale, R | 1 |
| Burstein, SA | 1 |
| Gillo, B | 1 |
| Ma, YS | 1 |
| Marks, AR | 2 |
| Zhuo, S | 2 |
| Fan, S | 2 |
| Huang, S | 1 |
| Kaufman, S | 3 |
| Ma, Y | 1 |
| Kobrinsky, E | 1 |
| Sparatore, B | 10 |
| Pessino, A | 5 |
| Patrone, M | 11 |
| Passalacqua, M | 9 |
| Melloni, E | 12 |
| Pontremoli, S | 12 |
| Comelli, M | 2 |
| Lippe, G | 1 |
| Mavelli, I | 3 |
| Kiyokawa, H | 5 |
| Richon, VM | 13 |
| Pietrangeli, P | 1 |
| Steinkühler, C | 1 |
| Marcocci, L | 1 |
| Pedersen, JZ | 1 |
| Mondovì, B | 1 |
| Andreani, A | 1 |
| Rambaldi, M | 1 |
| Locatelli, A | 1 |
| Andreani, F | 1 |
| Lollini, PL | 1 |
| Nanni, P | 1 |
| Bossa, R | 1 |
| Galatulas, I | 1 |
| Palitti, F | 1 |
| Carotti, D | 2 |
| Busiello, V | 1 |
| Bendicenti, A | 1 |
| Strom, R | 1 |
| Di Girolamo, M | 1 |
| Venta-Perez, G | 2 |
| Pilz, RB | 3 |
| Yamashita, K | 1 |
| Ohashi, H | 1 |
| Kagami, Y | 1 |
| Tsushita, K | 1 |
| Kinoshita, T | 1 |
| Hotta, T | 1 |
| Saito, H | 1 |
| Yoshida, S | 1 |
| Mori, KJ | 1 |
| Green, AR | 1 |
| Rockman, S | 1 |
| DeLuca, E | 1 |
| Begley, CG | 1 |
| Cogliati, T | 1 |
| Dunn, BK | 1 |
| Bar-Ner, M | 1 |
| Cultraro, CM | 1 |
| Segal, S | 2 |
| Cuddihy, AE | 1 |
| Brents, LA | 1 |
| Aziz, N | 1 |
| Kuehl, WM | 1 |
| Arcangeli, A | 5 |
| Carlà, M | 2 |
| Del Bene, MR | 1 |
| Becchetti, A | 1 |
| Wanke, E | 1 |
| Olivotto, M | 3 |
| Picard, V | 1 |
| Renaudie, F | 1 |
| Porcher, C | 1 |
| Hentze, MW | 1 |
| Grandchamp, B | 1 |
| Beaumont, C | 1 |
| Webb, Y | 2 |
| Merger, R | 1 |
| Sheppard, T | 1 |
| Jursic, B | 2 |
| Ngo, L | 5 |
| Civoli, F | 1 |
| Breslow, R | 4 |
| Dai, W | 1 |
| Pan, HQ | 1 |
| Ouyang, B | 1 |
| Greenberg, JM | 1 |
| Means, RT | 1 |
| Li, B | 1 |
| Cardie, J | 1 |
| Patterson, KK | 1 |
| Beckman, BS | 4 |
| Klotz, DM | 1 |
| Mallia, CM | 2 |
| Jeter, JR | 3 |
| Salzberg, S | 2 |
| Heller, A | 2 |
| Zou, JP | 1 |
| Collart, FR | 1 |
| Huberman, E | 1 |
| Ferreira, GM | 1 |
| Wölfle, H | 1 |
| Zicca, A | 1 |
| Suhasini, M | 1 |
| Boss, GR | 2 |
| Pascual, FE | 1 |
| Zaker, F | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| IGHID 11424 - A Pilot Trial of the Effect of Vorinostat and AGS-004 on Persistent HIV-1 Infection (The VOR VAX Study)[NCT02707900] | Phase 1 | 6 participants (Actual) | Interventional | 2016-03-31 | Terminated (stopped due to Manufacturing of the AGS-004 HIV vaccine by Argos could no longer be provided.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
14 reviews available for hexamethylene bisacetamide and Leukemia, Erythroblastic, Acute
| Article | Year |
|---|---|
Commitment to terminal differentiation and the cell cycle.
Topics: Acetamides; Animals; Butyrates; Cell Cycle; Cell Differentiation; Cell Division; Dexamethasone; Dime | 1982 |
In vitro studies on the mechanism of tumor promoter-mediated inhibition of cell differentiation.
Topics: Acetamides; Animals; Butyrates; Cell Adhesion; Cell Differentiation; Cell Division; Cell Line; Cell | 1982 |
Inducing differentiation of transformed cells with hybrid polar compounds: a cell cycle-dependent process.
Topics: Acetamides; Animals; Antineoplastic Agents; Cell Cycle; Cell Differentiation; Cell Line, Transformed | 1994 |
Cell cycle regulatory proteins are targets for induced differentiation of transformed cells: Molecular and clinical studies employing hybrid polar compounds.
Topics: Acetamides; Animals; Cell Cycle Proteins; Cell Differentiation; Cell Line, Transformed; Humans; Leuk | 1996 |
Induced differentiation, the cell cycle, and the treatment of cancer.
Topics: Acetamides; Antineoplastic Agents; Carrier Proteins; Cell Cycle; Cell Cycle Proteins; Cell Division; | 1996 |
Role of differentiation induction in tumor suppression.
Topics: Acetamides; Animals; Antineoplastic Agents; Cell Differentiation; Drug Evaluation; Drug Resistance; | 1990 |
Approaches to more effective induction of cytodifferentiation of transformed cells and potential for cancer treatment.
Topics: Acetamides; Animals; Cell Differentiation; Humans; Leukemia, Erythroblastic, Acute; Neoplasms; Oncog | 1990 |
Induced differentiation of erythroleukemia cells by hexamethylene bisacetamide: a model for cytodifferentiation of transformed cells.
Topics: Acetamides; Animals; Cell Differentiation; Cell Line, Transformed; Drug Evaluation; Gene Expression | 1989 |
Hexamethylene bisacetamide-induced differentiation of transformed cells: molecular and cellular effects and therapeutic application.
Topics: Acetamides; Animals; Cell Differentiation; Leukemia, Erythroblastic, Acute; Mice; Phenotype; Tumor C | 1988 |
DNA hypomethylation and differentiation of Friend erythroleukemia cells.
Topics: 5-Methylcytosine; Acetamides; Cell Differentiation; Cell Line; Cytosine; DNA, Neoplasm; Friend murin | 1988 |
Induced erythroleukemia differentiation: cellular and molecular aspects.
Topics: Acetamides; Animals; Calcium; Cell Differentiation; Diglycerides; Gene Expression Regulation; Globin | 1987 |
Induction of transformed cells to terminal differentiation.
Topics: Acetamides; Animals; Cell Differentiation; Cell Transformation, Neoplastic; Cell Transformation, Vir | 1987 |
Hexamethylene bisacetamide: a polar-planar compound entering clinical trials as a differentiating agent.
Topics: Acetamides; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Differentiation; Cell Line | 1986 |
Modulation of gene expression during terminal cell differentiation.
Topics: Acetamides; Cell Differentiation; Cell Division; Cell Line; Chromatin; DNA; DNA Replication; Erythro | 1985 |
192 other studies available for hexamethylene bisacetamide and Leukemia, Erythroblastic, Acute
| Article | Year |
|---|---|
Bis-pyrrolyl-tetrazolyl derivatives as hybrid polar compounds: A case of lipophilic functional bioisosterism with bis-acetamides.
Topics: Acetamides; Animals; Antineoplastic Agents; Cell Cycle; Cell Differentiation; Cell Proliferation; Gl | 2012 |
Differential expression of Ran GTPase during HMBA-induced differentiation in murine erythroleukemia cells.
Topics: Acetamides; Animals; Antineoplastic Agents; Blotting, Northern; Cell Cycle; Cell Death; Cell Differe | 2003 |
New designed HMBA agents as inducers of erythroleukemia cell differentiation.
Topics: Acetamides; Animals; Antineoplastic Agents; Cell Differentiation; Cell Division; Globins; Humans; K5 | 2002 |
Histone H4 hyperacetylation precludes histone H4 lysine 20 trimethylation.
Topics: Acetamides; Acetylation; Amino Acid Sequence; Animals; Antineoplastic Agents; Blotting, Western; But | 2004 |
Temporal changes in the expression of protein phosphatase 1 and protein phosphatase 2A in proliferating and differentiating murine erythroleukaemia cells.
Topics: Acetamides; Animals; Blotting, Western; Cell Differentiation; Cell Proliferation; Gene Expression Re | 2005 |
Protein kinase clk/STY is differentially regulated during erythroleukemia cell differentiation: a bias toward the skipped splice variant characterizes postcommitment stages.
Topics: Acetamides; Alternative Splicing; Animals; Cell Differentiation; Cell Line, Tumor; Exons; Gene Expre | 2005 |
Increased HEXIM1 expression during erythroleukemia and neuroblastoma cell differentiation.
Topics: Acetamides; Animals; Cell Differentiation; Cell Line, Tumor; Dimethyl Sulfoxide; Gene Expression Reg | 2006 |
Microarray profiling of genes differentially expressed during erythroid differentiation of murine erythroleukemia cells.
Topics: Acetamides; Animals; Cell Differentiation; Cluster Analysis; Expressed Sequence Tags; Gene Expressio | 2005 |
1,6-Diaminohexane contributes to the hexamethylene bisacetamide-induced erythroid differentiation pathway by stimulating Ca2+ release from inositol 1,4,5-trisphosphate-sensitive stores and promoting Ca2+ influx.
Topics: Acetamides; Acetylation; Animals; Boron Compounds; Calcium; Cell Differentiation; Cell Line, Tumor; | 2006 |
The carbonic anhydrase I locus contains a c-Myb target promoter and modulates differentiation of murine erythroleukemia cells.
Topics: Acetamides; Animals; Antineoplastic Agents; Base Sequence; Carbonic Anhydrase I; Cell Differentiatio | 2006 |
Temporal variation in the expression of the p53 protein in proliferating and differentiating murine erythroleukaemia cells.
Topics: Acetamides; Animals; Antineoplastic Agents; Cell Differentiation; Cell Line, Tumor; Cell Proliferati | 2007 |
Proteomic analysis of erythroid differentiation induced by hexamethylene bisacetamide in murine erythroleukemia cells.
Topics: Acetamides; Animals; Cell Differentiation; Cell Line, Tumor; Electrophoresis, Gel, Two-Dimensional; | 2007 |
PU.1 is dispensable to block erythroid differentiation in Friend erythroleukemia cells.
Topics: Acetamides; Animals; Azacitidine; Cell Differentiation; Decitabine; Drug Resistance; Erythroid Cells | 2008 |
Polyamine biosynthesis enzymes in the induction and inhibition of differentiation in Friend erythroleukemia cells.
Topics: Acetamides; Animals; Butyrates; Carboxy-Lyases; Cell Differentiation; Dexamethasone; Diamines; Dimet | 1980 |
Variations in the response of cloned murine friend erythroleukemia cells to different inducers.
Topics: Acetamides; Animals; Butyrates; Cell Division; Cell Line; Clone Cells; Diamines; Dimethyl Sulfoxide; | 1981 |
Effect of dexamethasone on hexamethylene bisacetamide-induced Friend cell erythrodifferentiation.
Topics: Acetamides; Animals; Cell Differentiation; Cell Division; Cell Line; Dexamethasone; Diamines; Dose-R | 1982 |
Inducer-mediated commitment of murine erythroleukemia cells to terminal cell division: the expression of commitment.
Topics: Acetamides; Animals; Cell Differentiation; Cell Division; Cell Line; Cycloheximide; Dexamethasone; G | 1984 |
Methylation of a middle repetitive DNA sequence class during differentiation in Friend erythroleukemia cells.
Topics: Acetamides; Animals; Base Sequence; Cell Differentiation; Cell Line; Deoxyribonuclease HpaII; DNA; D | 1984 |
DNA methylation and regulation of the human beta-globin-like genes in mouse erythroleukemia cells containing human chromosome 11.
Topics: Acetamides; Animals; Azacitidine; Cell Line; Chromosomes, Human, 6-12 and X; DNA; Gene Expression Re | 1984 |
Releasing effect of thymidine on G1 phase arrest of erythroleukemia cells caused by FUDR and HMBA.
Topics: Acetamides; Animals; Butyrates; Butyric Acid; Cell Differentiation; Cell Division; Clone Cells; Dact | 1984 |
Murine erythroleukemia cell differentiation: DNase I hypersensitivity and DNA methylation near the globin genes.
Topics: Acetamides; Animals; Base Sequence; Cell Differentiation; Cell Line; Chromatin; Deoxyribonuclease I; | 1982 |
Gene expression in murine erythroleukemia cells. Transcriptional control and chromatin structure of the alpha 1-globin gene.
Topics: Acetamides; Animals; Cell Line; Chromatin; Deoxyribonuclease I; DNA; Endodeoxyribonucleases; Endonuc | 1984 |
Differentiation of murine erythroleukemia cells results in the rapid repression of vimentin gene expression.
Topics: Acetamides; Actins; Animals; Cell Differentiation; Chickens; Cytoskeleton; Dimethyl Sulfoxide; Fluor | 1984 |
Transcriptional and post-transcriptional regulation of globin gene accumulation in murine erythroleukemia cells.
Topics: Acetamides; Animals; Butyrates; Cell Line; Gene Expression Regulation; Globins; Hemin; Leukemia, Ery | 1983 |
Erythroleukemia cells: variants inducible for hemoglobin synthesis without commitment to terminal cell division.
Topics: Acetamides; Animals; Butyrates; Cell Differentiation; Cell Division; Cells, Cultured; Dimethyl Sulfo | 1983 |
Desferrioxamine-mediated inhibition of heme and hemoglobin synthesis in murine erythroleukemia cells: expression of globin genes and commitment to erythroid differentiation.
Topics: Acetamides; Animals; Cell Differentiation; Cell Division; Cells, Cultured; Deferoxamine; Erythropoie | 1983 |
Transport of the folate compound methotrexate decreases during differentiation of murine erythroleukemia cells.
Topics: Acetamides; Animals; Biological Transport, Active; Cell Differentiation; Cell Line; Dimethyl Sulfoxi | 1984 |
Kinetics of histone H10 accumulation and commitment to differentiation in murine erythroleukemia cells.
Topics: Acetamides; Animals; Cell Cycle; Cell Differentiation; Cell Line; Electrophoresis, Polyacrylamide Ge | 1984 |
Regulation of nucleosomal core histone variant levels in differentiating murine erythroleukemia cells.
Topics: Acetamides; Animals; Cell Differentiation; Cell Line; Cytarabine; Dimethyl Sulfoxide; DNA Replicatio | 1984 |
Modulations of glycerophosphorylcholine and phosphorylcholine in Friend erythroleukemia cells upon in vitro-induced erythroid differentiation: a 31P NMR study.
Topics: Acetamides; Animals; Cell Differentiation; Choline; Clone Cells; Dimethyl Sulfoxide; Erythrocytes; G | 1984 |
Comparative study of two groups of inducers of Friend erythroleukemia cell differentiation in a chemically defined medium.
Topics: Acetamides; Animals; Cell Differentiation; Cell Line; Dactinomycin; Diamines; Dimethyl Sulfoxide; Er | 1981 |
DNA polymerase activities during induced differentiation in murine erythroleukemia cells.
Topics: Acetamides; Animals; Cell Cycle; Cell Differentiation; Cell Division; Cell Separation; Cells, Cultur | 1981 |
Inhibition of induced L-ornithine decarboxylase stimulation and erythrodifferentiation in Friend erythroleukemia cells by 2',5'-isoadenylate trimer core.
Topics: Acetamides; Adenosine; Animals; Carboxy-Lyases; Cell Differentiation; Cell Line; Diamines; Dimethyl | 1981 |
Comparison of nuclear proteins of differentiation-induced and uninduced Friend erythroleukemia cells.
Topics: Acetamides; Animals; Cell Differentiation; Cell Nucleus; Chromosomal Proteins, Non-Histone; Diamines | 1981 |
Comparison of dexamethasone binding and resistance to inhibition of induced differentiation in subclones of murine erythroleukemia cells.
Topics: Acetamides; Animals; Cell Differentiation; Clone Cells; Dexamethasone; Diamines; Drug Resistance; Le | 1981 |
Dexamethasone inhibits a heme-independent event necessary for terminal differentiation of murine erythroleukemia cells.
Topics: Acetamides; Animals; Cell Differentiation; Cells, Cultured; Dexamethasone; Diamines; Gene Expression | 1981 |
Inducer-mediated commitment of murine erythroleukemia cells to differentiation: a multistep process.
Topics: Acetamides; Animals; Cell Differentiation; Cell Division; Cell Line; Chromatin; Dexamethasone; Diami | 1982 |
Induction of mouse erythroleukemia cells by microinjection of inducing compound.
Topics: Acetamides; Animals; Cell Line; Cytological Techniques; Diamines; Erythropoiesis; Hemoglobins; Leuke | 1981 |
Induction of specific protein tyrosine phosphatase transcripts during differentiation of mouse erythroleukemia cells.
Topics: Acetamides; Animals; Blotting, Northern; Cell Differentiation; Cell Line; DNA Probes; Enzyme Inducti | 1994 |
Hexamethylene bisacetamide-induced differentiation of Friend virus-transformed murine erythroleukemia cells is associated with parallel changes in casein kinase II and guanine nucleotide exchange factor activities.
Topics: Acetamides; Animals; Antineoplastic Agents; Casein Kinase II; Cell Differentiation; Cell Division; C | 1995 |
Regulation of ferritin H-chain expression in differentiating Friend leukemia cells.
Topics: Acetamides; Animals; Cell Differentiation; Deferoxamine; Dimethyl Sulfoxide; Erythroid Precursor Cel | 1995 |
Spermine induces haemoglobin synthesis in murine erythroleukaemia cells.
Topics: Acetamides; Animals; Cell Cycle; Cell Division; Cell Size; Erythropoiesis; Globins; Hemoglobins; Leu | 1995 |
Iron-responsive element-binding protein mRNA levels during erythroid differentiation of murine erythroleukemia cells.
Topics: Acetamides; Animals; Butyrates; Butyric Acid; Cell Differentiation; Dimethyl Sulfoxide; Enzyme Induc | 1995 |
Identification and conditions for selective expression of megakaryocytic markers in Friend erythroleukemia cells.
Topics: Acetamides; Acetylcholinesterase; Animals; Biomarkers; Cell Differentiation; Fetal Blood; Flow Cytom | 1995 |
Calcium influx in induced differentiation of murine erythroleukemia cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1993 |
Study of the role of retinoblastoma protein in terminal differentiation of murine erythroleukemia cells.
Topics: Acetamides; Animals; Antineoplastic Agents; Cell Cycle; Cell Differentiation; Cell Line; Cell Line, | 1995 |
Cloning and expression of a novel truncated calcium channel from non-excitable cells.
Topics: Acetamides; Alternative Splicing; Amino Acid Sequence; Animals; Base Sequence; Blotting, Western; Ca | 1995 |
Changes in calcium influx affect the differentiation of murine erythroleukaemia cells.
Topics: Acetamides; Animals; Calcium; Calpain; Cell Differentiation; Cell Membrane; Cell Membrane Permeabili | 1995 |
Modulation of the intracellular Ca(2+)-dependent proteolytic system is critically correlated with the kinetics of differentiation of murine erythroleukemia cells.
Topics: Acetamides; Antibodies; Antineoplastic Agents; Calcium; Calcium-Binding Proteins; Calpain; Cell Diff | 1994 |
Differentiation potentiates oxidant injury to mitochondria by hydrogen peroxide in Friend's erythroleukemia cells.
Topics: Acetamides; Animals; Antioxidants; Atractyloside; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone | 1994 |
Suppression of cyclin-dependent kinase 4 during induced differentiation of erythroleukemia cells.
Topics: Acetamides; Amino Acid Sequence; Animals; Base Sequence; Carrier Proteins; CDC2-CDC28 Kinases; Cell | 1994 |
Enhancement of daunomycin toxicity by the differentiation inducer hexamethylene bisacetamide in erythroleukemia cells.
Topics: Acetamides; Animals; Catalase; Cell Differentiation; Cell Line; Cell-Free System; Daunorubicin; Drug | 1994 |
Potential antitumor agents. 23.(1) Cytotoxic and differentiating activity of compounds related to hexamethylenebisacetamide.
Topics: Acetamides; Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Cell Differentiation; Cell Sur | 1993 |
Protein kinase C isoforms in murine erythroleukemia cells and their involvement in the differentiation process.
Topics: Acetamides; Animals; Cell Differentiation; Chromatography, DEAE-Cellulose; Immunoblotting; Isoenzyme | 1994 |
DNA hypomethylation and differentiation in Friend leukemia cell variants.
Topics: Acetamides; Animals; Cell Differentiation; Clone Cells; Cytosine; DNA; Friend murine leukemia virus; | 1993 |
Hexamethylenebisacetamide-induced erythroleukemia cell differentiation involves modulation of events required for cell cycle progression through G1.
Topics: Acetamides; Animals; Aphidicolin; Cell Differentiation; Cyclins; Deferoxamine; G1 Phase; Leukemia, E | 1993 |
Impaired erythroid-specific gene expression in cAMP-dependent protein kinase-deficient murine erythroleukemia cells.
Topics: 5-Aminolevulinate Synthetase; Acetamides; Aminolevulinic Acid; Animals; Blotting, Northern; Cell Dif | 1993 |
Erythroid potentiating activity of tissue inhibitor of metalloproteinases on the differentiation of erythropoietin-responsive mouse erythroleukemia cell line, ELM-I-1-3, is closely related to its cell growth potentiating activity.
Topics: Acetamides; Animals; Antibodies; Cell Differentiation; Cell Division; DNA, Neoplasm; Erythroid Precu | 1993 |
Induced myeloid differentiation of K562 cells with downregulation of erythroid and megakaryocytic transcription factors: a novel experimental model for hemopoietic lineage restriction.
Topics: Acetamides; Animals; Antigens, Surface; Cell Cycle; Cell Differentiation; Cell Division; Erythrocyte | 1993 |
Transfected wild-type and mutant max regulate cell growth and differentiation of murine erythroleukemia cells.
Topics: Acetamides; Animals; Base Sequence; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Bas | 1993 |
Only the DNA binding and transactivation domains of c-Myb are required to block terminal differentiation of murine erythroleukemia cells.
Topics: Acetamides; Animals; Base Sequence; Cell Differentiation; Cell Nucleus; DNA-Binding Proteins; Friend | 1993 |
Role of delta-PKC on the differentiation process of murine erythroleukemia cells.
Topics: Acetamides; Animals; Base Sequence; Cell Differentiation; Isoenzymes; Leukemia, Erythroblastic, Acut | 1993 |
Polar/apolar compounds induce leukemia cell differentiation by modulating cell-surface potential.
Topics: Acetamides; Animals; Antineoplastic Agents; Cell Differentiation; Cell Membrane; Chlorides; Dimethyl | 1993 |
Antisense oligodeoxynucleotide inhibition of delta protein kinase C expression accelerates induced differentiation of murine erythroleukaemia cells.
Topics: Acetamides; Animals; Antigen-Antibody Complex; Antineoplastic Agents; Base Sequence; Cell Differenti | 1995 |
Effects of depletion of intracellular tetrahydrobiopterin in murine erythroleukemia cells.
Topics: Acetamides; Alcohol Oxidoreductases; Animals; Biopterins; Cell Differentiation; Cell Division; Enzym | 1996 |
Overexpression of the ferritin H subunit in cultured erythroid cells changes the intracellular iron distribution.
Topics: Acetamides; Aminolevulinic Acid; Animals; Base Sequence; Cell Compartmentation; Cell Differentiation | 1996 |
Second generation hybrid polar compounds are potent inducers of transformed cell differentiation.
Topics: Acetamides; Animals; Antineoplastic Agents; Cell Cycle; Cell Differentiation; Leukemia, Erythroblast | 1996 |
Expression of receptor protein tyrosine kinase tif is regulated during leukemia cell differentiation.
Topics: Acetamides; Base Sequence; Cell Differentiation; Down-Regulation; Gene Expression Regulation, Enzymo | 1996 |
Dexniguldipine hydrochloride, a protein-kinase-C-specific inhibitor, affects the cell cycle, differentiation, P-glycoprotein levels, and nuclear protein phosphorylation in Friend erythroleukemia cells.
Topics: Acetamides; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; | 1996 |
Changes in E2F DNA-binding activity during induced erythroid differentiation.
Topics: Acetamides; Animals; Antineoplastic Agents; Base Sequence; Carrier Proteins; Cell Cycle; Cell Cycle | 1996 |
Interferon-independent activation of (2'-5') oligoadenylate synthetase in Friend erythroleukemia cell variants exposed to HMBA.
Topics: 2',5'-Oligoadenylate Synthetase; Acetamides; Animals; Antineoplastic Agents; Cell Differentiation; e | 1996 |
Extracellular high-mobility group 1 protein is essential for murine erythroleukaemia cell differentiation.
Topics: Acetamides; Animals; Antineoplastic Agents; Calcimycin; Cell Differentiation; High Mobility Group Pr | 1996 |
High frequency oscillations in the activity of phosphotyrosine phosphatase in murine erythroleukaemic cells: action of insulin and hexamethylene bisacetamide.
Topics: Acetamides; Activity Cycles; Animals; Cell Differentiation; Insulin; Kinetics; Leukemia, Erythroblas | 1996 |
Secretion and binding of HMG1 protein to the external surface of the membrane are required for murine erythroleukemia cell differentiation.
Topics: Acetamides; Animals; Antibodies, Monoclonal; Cell Differentiation; Cell Membrane; Endoplasmic Reticu | 1997 |
Nitric oxide-releasing agents and cGMP analogues inhibit murine erythroleukemia cell differentiation and suppress erythroid-specific gene expression: correlation with decreased DNA binding of NF-E2 and altered c-myb mRNA expression.
Topics: 5-Aminolevulinate Synthetase; Acetamides; Animals; Base Sequence; Cell Differentiation; Cell Line; C | 1995 |
Oncogenic RAS genes impair erythroid differentiation of erythroleukaemia cells.
Topics: Acetamides; Animals; Antineoplastic Agents; Cell Cycle; Cell Differentiation; Cell Division; Genes, | 1997 |
Effects of intracellular chelatable iron and oxidative stress on transcription of classical cellular glutathione peroxidase gene in murine erythroleukemia cells.
Topics: Acetamides; Animals; Erythroid Precursor Cells; Gene Expression Regulation, Enzymologic; Gene Expres | 1997 |
Differentiation inducers modulate cytokine signaling pathways in a murine erythroleukemia cell line.
Topics: Acetamides; Animals; Antineoplastic Agents; Cattle; Cell Differentiation; Cytokines; DNA-Binding Pro | 1998 |
A class of hybrid polar inducers of transformed cell differentiation inhibits histone deacetylases.
Topics: Acetamides; Animals; Carcinoma; Cell Differentiation; Cell Line, Transformed; Cell Transformation, N | 1998 |
Dephosphorylation of Vav is associated with the induction of mouse erythroleukemia cell differentiation: effects of orthovanadate and levamisole.
Topics: Acetamides; Adjuvants, Immunologic; Animals; Antineoplastic Agents; Cell Differentiation; Leukemia, | 1998 |
Severe energy impairment consequent to inactivation of mitochondrial ATP synthase as an early event in cell death: a mechanism for the selective sensitivity to H2O2 of differentiating erythroleukemia cells.
Topics: Acetamides; Animals; ATP Synthetase Complexes; Cell Death; Cell Differentiation; Cell Division; Ener | 1998 |
Regulation of human globin gene expression in mouse erythroleukemia x human fibroblast hybrid cells.
Topics: Acetamides; Animals; Antineoplastic Agents; Chelating Agents; Deoxyribonucleases; DNA, Complementary | 1982 |
cAMP-dependent phosphorylation and hexamethylene-bis-acetamide induced dephosphorylation of p19 in murine erythroleukemia cells.
Topics: Acetamides; Animals; Antibodies; Antineoplastic Agents; Calcium-Calmodulin-Dependent Protein Kinases | 1998 |
Protein kinase calpha is an effector of hexamethylene bisacetamide-induced differentiation of Friend erythroleukemia cells.
Topics: Acetamides; Animals; Cell Differentiation; Friend murine leukemia virus; Globins; Humans; Isoenzymes | 1999 |
Bcl-XL induction during terminal differentiation of friend erythroleukaemia cells correlates with delay of apoptosis and loss of proliferative capacity but not with haemoglobinization.
Topics: Acetamides; Animals; Apoptosis; bcl-X Protein; Cell Cycle; Cell Differentiation; Cell Division; Cell | 1999 |
Notch-1 inhibits apoptosis in murine erythroleukemia cells and is necessary for differentiation induced by hybrid polar compounds.
Topics: Acetamides; Animals; Apoptosis; Cell Differentiation; Cell Division; Clone Cells; Down-Regulation; H | 1999 |
Transcription factor CP2 is crucial in hemoglobin synthesis during erythroid terminal differentiation in vitro.
Topics: Acetamides; Animals; Antisense Elements (Genetics); Cell Differentiation; DNA-Binding Proteins; Eryt | 1999 |
Rhythmic patterns in the expression of the ras oncogene in proliferating and differentiating erythroleukaemia cells.
Topics: Acetamides; Animals; Antineoplastic Agents; Blotting, Northern; Blotting, Western; Cell Differentiat | 2000 |
Protein kinase c in erythroleukaemia cells: temporal variations in the expression of the alpha, epsilon and zeta isoforms.
Topics: Acetamides; Animals; Blotting, Western; Cell Differentiation; Electrophoresis, Polyacrylamide Gel; I | 2000 |
Manipulating the onset of cell cycle withdrawal in differentiated erythroid cells with cyclin-dependent kinases and inhibitors.
Topics: Acetamides; Animals; CDC2-CDC28 Kinases; Cell Cycle; Cell Differentiation; Cell Division; Cyclin-Dep | 2000 |
A transient dephosphorylation of JAK1 and JAK2 characterises the early-phase response of murine erythroleukemia cells to the differentiation inducer hexamethylenebisacetamide.
Topics: Acetamides; Animals; Cell Differentiation; Janus Kinase 1; Janus Kinase 2; Leukemia, Erythroblastic, | 2000 |
Structural characterization of erythroid and megakaryocytic differentiation in Friend erythroleukemia cells.
Topics: Acetamides; Animals; bcl-2-Associated X Protein; Cell Differentiation; Cyclin-Dependent Kinase 4; Cy | 2001 |
A Myb dependent pathway maintains Friend murine erythroleukemia cells in an immature and proliferating state.
Topics: Acetamides; Animals; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Basic-Leucine Zipp | 2002 |
Effect of hexamethylene bisacetamide on the commitment to differentiation of murine erythroleukemia cells.
Topics: Acetamides; Animals; Cell Differentiation; Cell Division; Clone Cells; Dimethyl Sulfoxide; DNA, Neop | 1977 |
Differential effects of chemical inducers on expression of beta globin genes in murine erythroleukemia cells.
Topics: Acetamides; Butyrates; Cell Differentiation; Cell Line; Cell-Free System; Dimethyl Sulfoxide; Genes; | 1977 |
Synthesis of globin mRNA in relation to the cell cycle during induced murine erythroleukemia differentiation.
Topics: Acetamides; Animals; Cell Cycle; Cell Differentiation; Cells, Cultured; Diamines; Dimethyl Sulfoxide | 1978 |
Stability of alpha and beta globin messenger RNA during induced differentiation of mouse erythroleukemia cells.
Topics: Acetamides; Animals; Cell Differentiation; Clone Cells; Diamines; Drug Stability; Globins; Hybridiza | 1979 |
Studies on the mechanism of action of hexamethylene bisacetamide, a potent inducer of erythroleukemic differentiation.
Topics: Acetamides; Animals; Cell Differentiation; Cell Line; Diamines; Erythrocytes; Leukemia, Erythroblast | 1979 |
Inhibition of expression of a mouse alpha-globin gene by plasmids that include antisense oligonucleotides.
Topics: Acetamides; Animals; Base Sequence; Cell Differentiation; DNA, Recombinant; Gene Expression Regulati | 1992 |
Synergistic induction of erythroid differentiation of mouse erythroleukemia (MEL) cells by inhibitors of topoisomerases and protein tyrosine kinases.
Topics: Acetamides; Amsacrine; Animals; Blotting, Western; Camptothecin; Cell Differentiation; Cinnamates; D | 1992 |
Changes in pyridine and adenine nucleotide levels in Friend erythroleukaemia cells during growth and differentiation.
Topics: Acetamides; Adenine Nucleotides; Adenosine Triphosphate; Animals; Cell Differentiation; Cell Divisio | 1992 |
Alteration of phosphotyrosine-containing proteins at the early stage of erythroid differentiation of mouse erythroleukemia (MEL) cells.
Topics: Acetamides; Animals; Antineoplastic Agents; Butyrates; Butyric Acid; Cell Differentiation; Cell Line | 1992 |
Changes in p34cdc2 kinase activity and cyclin A during induced differentiation of murine erythroleukemia cells.
Topics: Acetamides; Animals; Base Sequence; CDC2 Protein Kinase; Cell Cycle; Cell Differentiation; Cyclins; | 1992 |
Expression and phosphorylation of the retinoblastoma protein during induced differentiation of murine erythroleukemia cells.
Topics: Acetamides; Animals; Cell Differentiation; Cell Division; Dexamethasone; Erythroid Precursor Cells; | 1992 |
A rise and fall in 1,2-diacylglycerol content signal hexamethylene bisacetamide-induced erythropoiesis.
Topics: Acetamides; Animals; Diglycerides; Drug Resistance; Erythropoiesis; Genetic Variation; Kinetics; Leu | 1992 |
Proliferation is required for induction of terminal differentiation of Friend erythroleukemia cells.
Topics: Acetamides; Animals; Aphidicolin; Cell Differentiation; Cell Division; DNA Replication; Friend murin | 1992 |
Alteration in proportions of histone H1 variants during the differentiation of murine erythroleukaemic cells.
Topics: Acetamides; Animals; Antineoplastic Agents; Butyrates; Butyric Acid; Cell Differentiation; Cell Divi | 1992 |
Constitutive expression of a megakaryocytic functional property by murine erythroleukemia (Friend) cells: the incorporation of serotonin.
Topics: Acetamides; Animals; Biological Transport, Active; Clomipramine; Cytoplasm; Erythroid Precursor Cell | 1992 |
Nuclear protein kinase C activity is decreased in Friend erythroleukemia cells induced to differentiate.
Topics: Acetamides; Alkaloids; Cell Division; Cell Nucleus; Cell Transformation, Viral; Dimethyl Sulfoxide; | 1992 |
Seric factors influence cell cycle modifications during commitment of murine erythroleukemia cells to differentiation.
Topics: Acetamides; Animals; Biomarkers, Tumor; Blood Proteins; Blotting, Northern; Butyrates; Cell Cycle; C | 1992 |
Chemically induced murine erythroleukemia cell differentiation is severely impaired when cAMP-dependent protein kinase activity is repressed by transfected genes.
Topics: Acetamides; Animals; Blotting, Northern; Blotting, Western; Cell Differentiation; Enzyme Repression; | 1992 |
Protein kinases associated with proliferation and differentiation in murine erythroleukaemic cells.
Topics: Acetamides; Animals; Cell Differentiation; Cell Division; Cyclic AMP; Cyclic GMP; Cytosol; Electroph | 1991 |
Inositol lipids in Friend erythroleukemia cells: evidence for changes in nuclear metabolism after differentiation.
Topics: Acetamides; Cell Differentiation; Cell Line; Cell Nucleus; Friend murine leukemia virus; Inositol Ph | 1991 |
Characteristics of erythroleukemia cells selected for vincristine resistance that have accelerated inducer-mediated differentiation.
Topics: Acetamides; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; | 1991 |
Reduction in lactate accumulation correlates with differentiation-induced terminal cell division of leukemia cells.
Topics: Acetamides; Animals; Carbon Dioxide; Cell Differentiation; Cell Division; Cell Transformation, Neopl | 1991 |
Enhanced intracellular activation of carboplatin in hemoglobin-synthesizing versus undifferentiated erythroleukemic cells.
Topics: Acetamides; Animals; Carboplatin; Cell Differentiation; Cell Survival; Cisplatin; DNA, Neoplasm; Hem | 1992 |
[Expression of protooncogenes c-myb and c-myc during the hexamethylene bisacetamide (HMBA)-induced commitment to terminal differentiation of murine erythroleukemia cells].
Topics: Acetamides; Animals; Cell Division; Drug Resistance; Gene Expression Regulation, Neoplastic; Genes, | 1991 |
Differentiation of murine erythroleukemia cells by hexamethylenebisacetamide involves secretion and binding to membranes of a differentiation enhancing factor.
Topics: Acetamides; Animals; Cell Differentiation; Cell Line; Cell Membrane; Cell Nucleus; Chromatography, I | 1991 |
In vitro phosphorylation of lamin B by protein kinase C in friend erythroleukemia. Effect of chemically induced differentiation.
Topics: Acetamides; Animals; Calcium; Cell Differentiation; Cell Nucleus; Egtazic Acid; Immunoelectrophoresi | 1991 |
Conversion of differentiation inducer resistance to differentiation inducer sensitivity in erythroleukemia cells.
Topics: Acetamides; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Differentiation; | 1990 |
Induction of in vitro differentiation of mouse erythroleukemia cells by genistein, an inhibitor of tyrosine protein kinases.
Topics: Acetamides; Animals; Benzidines; Cell Differentiation; Dexamethasone; Dimethyl Sulfoxide; Genistein; | 1991 |
Cell cycle-related accumulation of H1(0) mRNA: induction in murine erythroleukemia cells.
Topics: Acetamides; Animals; Cell Cycle; Cell Line; Clone Cells; DNA Probes; Hematinics; Histones; Kinetics; | 1991 |
Potent cytodifferentiating agents related to hexamethylenebisacetamide.
Topics: Acetamides; Cell Differentiation; Drug Synergism; Erythropoiesis; Humans; Hydroxamic Acids; In Vitro | 1991 |
Electrophoretic separation of protein kinases: altered mobility with different crosslinking agents in the presence of certain detergents.
Topics: Acetamides; Acrylamides; Animals; Cross-Linking Reagents; Cyclic AMP; Detergents; Electrophoresis, P | 1990 |
Nuclear inositol lipids in Friend erythroleukemia cells. Changes related to differentiation induced by hexamethylenebisacetamide.
Topics: Acetamides; Cell Differentiation; Cell Line; Cell Nucleus; Friend murine leukemia virus; Inositol; L | 1990 |
Induction by HMBA and DMSO of genes introduced into mouse erythroleukemia and other cell lines by transient transfection.
Topics: Acetamides; Animals; Base Sequence; Cell Line; Dimethyl Sulfoxide; Gene Expression Regulation; Globi | 1990 |
Murine erythroleukemia cell differentiation: possible involvement of a calcium dependent neutral proteinase.
Topics: Acetamides; Animals; Calcium; Calpain; Cell Differentiation; Enzyme Activation; Hemoglobins; Kinetic | 1990 |
Increased retinoblastoma gene expression is associated with late stages of differentiation in many different cell types.
Topics: Acetamides; Animals; B-Lymphocytes; Cell Differentiation; Dimethyl Sulfoxide; Embryo, Mammalian; Gen | 1990 |
Alterations in electrophoretic mobility, diaphorase activity, and terminal differentiation induced in murine erythroleukemia lines by differentiating agents.
Topics: Acetamides; Animals; Cell Differentiation; Dihydrolipoamide Dehydrogenase; Dimethyl Sulfoxide; Elect | 1990 |
Dielectrophoretic characterisation of Friend murine erythroleukaemic cells as a measure of induced differentiation.
Topics: Acetamides; Animals; Cell Differentiation; Cell Line; Cell Membrane; Electric Conductivity; Electrop | 1990 |
Synergistic action of activin A and hexamethylene bisacetamide in differentiation of murine erythroleukemia cells.
Topics: Acetamides; Activins; Animals; Cell Count; Cell Differentiation; Dexamethasone; Dose-Response Relati | 1990 |
Introduction of the beta isozyme of protein kinase C accelerates induced differentiation of murine erythroleukemia cells.
Topics: Acetamides; Animals; Brain; Cell Differentiation; Cell Line; Drug Resistance; Isoenzymes; Kinetics; | 1990 |
Combination cytotoxic-differentiation therapy of mouse erythroleukemia cells with 5-fluorouracil and hexamethylene bisacetamide.
Topics: Acetamides; Animals; Cell Count; Cell Differentiation; Cell Division; Dexamethasone; Dimethyl Sulfox | 1990 |
Relationship between globin mRNA accumulation and commitment to terminal cell differentiation in inducer sensitive and resistant erythroleukemia variants.
Topics: Acetamides; Animals; Cell Differentiation; Cell Division; Dimethyl Sulfoxide; Drug Resistance; Genet | 1990 |
Butyrate induces expression of transfected human fetal and endogenous mouse embryonic globin genes in GM 979 erythroleukemia cells.
Topics: Acetamides; Animals; Blotting, Southern; Butyrates; Butyric Acid; Dimethyl Sulfoxide; Gene Expressio | 1990 |
Commitment to differentiation of murine erythroleukemia cells involves a modulated plasma membrane depolarization through Ca2+-activated K+ channels.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Acetamides; Animals; Calcimycin; Calcium | 1987 |
Detection of 5-methylcytosine removal from DNA of Friend erythroleukemia cells following exposure to several differentiating agents.
Topics: 5-Methylcytosine; Acetamides; Animals; Cell Differentiation; Cytosine; Dimethyl Sulfoxide; DNA; Frie | 1989 |
Hemin and cyclic AMP stimulate message-dependent translation in lysates from Friend erythroleukemia cells.
Topics: Acetamides; Animals; Cell Line, Transformed; Cell-Free System; Cyclic AMP; Friend murine leukemia vi | 1989 |
Cancer reversal: regulation of phosphotyrosine phosphatase.
Topics: Acetamides; Animals; Cell Differentiation; Cell Transformation, Neoplastic; Dexamethasone; Leukemia, | 1989 |
Beta globin gene transcripts originating in the promoter region during early hexamethylene bisacetamide and dimethylsulfoxide induction of Friend erythroleukemia cells.
Topics: Acetamides; Cell Line; Dimethyl Sulfoxide; Friend murine leukemia virus; Gene Expression Regulation; | 1989 |
Inhibition of cellular iron uptake by haem in mouse erythroleukaemia cells.
Topics: Acetamides; Aminolevulinic Acid; Animals; Cell Differentiation; Cells, Cultured; Glycine; Heme; Hemi | 1989 |
Induced differentiation of murine erythroleukemia cells (MELC) by polar compounds: marked increased sensitivity of vincristine resistant MELC.
Topics: Acetamides; Animals; Antineoplastic Agents; Cell Differentiation; Cell Division; Drug Resistance; Er | 1989 |
Rapid induction of human alpha, beta and gamma globin genes in transiently transfected mouse erythroleukemia cells.
Topics: Acetamides; Animals; Cell Differentiation; Dexamethasone; Electricity; Gene Expression Regulation; G | 1989 |
Modulation of the c-myb, c-myc and p53 mRNA and protein levels during induced murine erythroleukemia cell differentiation.
Topics: Acetamides; Animals; Cell Differentiation; Dexamethasone; Leukemia, Erythroblastic, Acute; Mice; Neo | 1989 |
Affinity isolation of transcriptionally active murine erythroleukemia cell DNA using a cleavable biotinylated nucleotide analog.
Topics: Acetamides; Animals; Bacterial Proteins; Biotin; Cell Differentiation; Chromatography, Affinity; Deo | 1989 |
Tetrahydrobiopterin, the cofactor for aromatic amino acid hydroxylases, is synthesized by and regulates proliferation of erythroid cells.
Topics: Acetamides; Animals; Biopterins; Cell Differentiation; Cell Division; Cell Line; DNA Replication; GT | 1989 |
Polar/apolar chemical inducers of differentiation of transformed cells: strategies to improve therapeutic potential.
Topics: Acetamides; Animals; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Leukemia, Ery | 1989 |
Different 3'-end processing produces two independently regulated mRNAs from a single H1 histone gene.
Topics: Acetamides; Amino Acid Sequence; Animals; Base Sequence; Cell Cycle; Cell Line; DNA, Neoplasm; Gene | 1989 |
Differential expression of protein kinase C isozymes and erythroleukemia cell differentiation.
Topics: Acetamides; Animals; Calcium; Cell Differentiation; Drug Resistance; Genetic Variation; Isoenzymes; | 1989 |
Regulation of murine alpha-, beta major-, and beta minor-globin gene expression.
Topics: Acetamides; Acetyltransferases; Animals; Chloramphenicol O-Acetyltransferase; DNA; DNA, Recombinant; | 1988 |
Regulation of ornithine decarboxylase in murine erythroleukemic cells by N,N'-diacetyl-1,6-hexanediamine and N-acetyl-1,6-hexanediamine.
Topics: Acetamides; Animals; Gene Expression Regulation; Genes; Kinetics; Leukemia, Erythroblastic, Acute; M | 1989 |
Interaction of urokinase with specific receptors abolishes the time of commitment to terminal differentiation of murine erythroleukaemia (Friend) cells.
Topics: Acetamides; Animals; Cell Differentiation; Cell Line; Friend murine leukemia virus; Leukemia, Erythr | 1987 |
Relationship between ornithine decarboxylase activity and hexamethylene bisacetamide-induced differentiation of murine erythroleukemia cells.
Topics: Acetamides; Animals; Cell Differentiation; Cell Line; Clone Cells; Dexamethasone; Eflornithine; Eryt | 1986 |
Effect of aphidicolin on Friend erythroleukemia cell maturation.
Topics: Acetamides; Animals; Aphidicolin; Cell Differentiation; Cell Division; Diterpenes; DNA Polymerase II | 1987 |
Effect of alpha-difluoromethylornithine on DNA methylation in murine erythroleukaemic cells. Relationship to stimulation of induced differentiation.
Topics: Acetamides; Animals; Cell Differentiation; Cells, Cultured; DNA; Eflornithine; Leukemia, Erythroblas | 1987 |
Modulation of murine erythroleukemic cell differentiation by inhibitors of polyamine biosynthesis.
Topics: Acetamides; Animals; Cell Differentiation; Cell Division; Cell Line; Depression, Chemical; Eflornith | 1987 |
PolyADP ribosylation and Friend erythroleukemic-cell differentiation: action of poly(ADP-ribose) polymerase inhibitors.
Topics: Acetamides; Animals; Benzamides; Cell Differentiation; Cell Division; Cell Line; Dimethyl Sulfoxide; | 1987 |
Vincristine-resistant erythroleukemia cell line has marked increased sensitivity to hexamethylenebisacetamide-induced differentiation.
Topics: Acetamides; Animals; Cell Differentiation; Cell Division; Dexamethasone; Drug Resistance; Erythropoi | 1988 |
A possible effect of heme on the fate of DNA ligase activity extracted from differentiating mouse erythroleukemia cells.
Topics: Acetamides; Adenosine Triphosphate; Animals; Cell Differentiation; Dimethyl Sulfoxide; DNA Ligases; | 1988 |
Changes in CuZn-superoxide dismutase during induced differentiation of murine erythroleukemia cells.
Topics: Acetamides; Animals; Cell Differentiation; Hemoglobins; Leukemia, Erythroblastic, Acute; Mice; Super | 1988 |
Relationship between transient DNA hypomethylation and erythroid differentiation of murine erythroleukemia cells.
Topics: Acetamides; Animals; Cell Differentiation; Cell Line; Cycloheximide; DNA, Neoplasm; Isomerism; Kinet | 1988 |
Characteristics of ether-linked glycerophospholipids in Friend erythroleukaemia cells differentiated by dimethyl sulphoxide or hexamethylenebisacetamide and in non-inducible clones treated with the inducers.
Topics: Acetamides; Animals; Cell Differentiation; Cell Line; Clone Cells; Dimethyl Sulfoxide; Friend murine | 1988 |
The effect of a transfected c-myc proto-oncogene on cellular differentiation.
Topics: Acetamides; Animals; Cell Differentiation; Cell Line; Humans; Leukemia, Erythroblastic, Acute; Mice; | 1988 |
Intracellular factors involved in erythroid differentiation of mouse erythroleukaemia cells.
Topics: Acetamides; Animals; Cell Fusion; Cell Transformation, Neoplastic; Dimethyl Sulfoxide; Erythrocytes; | 1988 |
Relationship between methylation of middle-repetitive DNA sequences in inducer-sensitive and resistant clones of Friend erythroleukemia cells and synthesis of poly(A)+ RNA containing homologous repetitive sequences.
Topics: Acetamides; Animals; Cell Differentiation; Cell Line; DNA, Neoplasm; Friend murine leukemia virus; G | 1988 |
Two-dimensional gel electrophoretic analysis of cytoplasmic proteins from Friend erythroleukemia cells chemically induced to undergo terminal erythroid differentiation.
Topics: Acetamides; Cell Differentiation; Cytoplasm; Electrophoresis; Friend murine leukemia virus; Leukemia | 1988 |
Early events in murine erythroleukemia cells induced to differentiate. Accumulation and gene expression of the transformation-associated cellular protein p53.
Topics: Acetamides; Animals; Cell Differentiation; Cell Line; Cycloheximide; Dactinomycin; Flow Cytometry; H | 1988 |
Antagonistic effect of butyrate on hexamethylene bisacetamide induced differentiation of murine erythroleukemia cells.
Topics: Acetamides; Animals; Butyrates; Butyric Acid; Cell Cycle; Cell Differentiation; Dose-Response Relati | 1986 |
Cytoplasmic synthesis of globin RNA in differentiated murine erythroleukemia cells: possible involvement of RNA-dependent RNA polymerase.
Topics: Acetamides; Animals; Cell Differentiation; Cell Line; Cytoplasm; Dactinomycin; Gene Expression Regul | 1986 |
Replacement of 5-methylcytosine by cytosine: a possible mechanism for transient DNA demethylation during differentiation.
Topics: 5-Methylcytosine; Acetamides; Animals; Base Sequence; Cell Differentiation; Cytosine; Dealkylation; | 1986 |
Effects of ornithine decarboxylase inhibition on c-myc expression during murine erythroleukemia cell proliferation and differentiation.
Topics: Acetamides; Animals; Cell Differentiation; Cell Division; Cell Line; Dimethyl Sulfoxide; Gene Expres | 1986 |
1-Oleoyl 2-acetyl glycerol inhibits differentiation of TPA-sensitive but not of TPA-resistant Friend cells.
Topics: Acetamides; Animals; Cell Adhesion; Cell Differentiation; Diglycerides; Dose-Response Relationship, | 1986 |
Uptake of fluorescent fatty acids by erythroleukemia cells. Effect of differentiation.
Topics: Acetamides; Animals; Cell Differentiation; Cell Line; Cell Separation; Dimethyl Sulfoxide; Erythrobl | 1986 |
Changes in gene expression associated with induced differentiation of erythroleukemia: protooncogenes, globin genes, and cell division.
Topics: Acetamides; Animals; Cell Differentiation; Cell Division; Cells, Cultured; Cycloheximide; Globins; L | 1986 |
Differentiation of murine erythroleukemic cells during exposure to microwave radiation.
Topics: Acetamides; Animals; Cell Differentiation; Cell Line; Friend murine leukemia virus; In Vitro Techniq | 1986 |
Induction of differentiation in Friend erythroleukemia cells with dimethyl sulfoxide, hexamethylene bisacetamide and sodium butyrate is not accompanied by changes in proviral DNA or its expression.
Topics: Acetamides; Animals; Butyrates; Butyric Acid; Cell Differentiation; Cell Line; Dimethyl Sulfoxide; D | 1986 |
Catabolites produced by the deacetylation of hexamethylenebisacetamide play a key role in murine erythroleukaemic-cell differentiation.
Topics: Acetamides; Animals; Cell Differentiation; Cells, Cultured; Kinetics; Leukemia, Erythroblastic, Acut | 1986 |
Protein kinase C activity and hexamethylenebisacetamide-induced erythroleukemia cell differentiation.
Topics: Acetamides; Animals; Calcium; Cell Differentiation; Cells, Cultured; Hemoglobins; Leukemia, Erythrob | 1987 |
Effect of dimethylsulfoxide and hexamethylene bisacetamide on the JOK-1 hairy cell leukemia derived cell line propagated in the nude mouse.
Topics: Acetamides; Animals; Cell Differentiation; Cell Line; Dimethyl Sulfoxide; Female; Leukemia, Erythrob | 1987 |
Lipid changes associated with erythroid differentiation of Friend erythroleukemia cells.
Topics: Acetamides; Animals; Cell Differentiation; Cell Line; Cholesterol; Dimethyl Sulfoxide; Fatty Acids, | 1987 |
Idiotype mimicry by a differentiation antigen on Friend erythroleukemia cells.
Topics: Acetamides; Animals; Antigens, Neoplasm; Antigens, Surface; Cell Differentiation; Cell Division; Cel | 1987 |
Glucocorticoid receptors in murine erythroleukaemic cells.
Topics: Acetamides; Animals; Binding, Competitive; Cell Differentiation; Cell Line; Dexamethasone; Friend mu | 1987 |
Precommitted erythroid cells enriched in cultures of suboptimally induced Friend erythroleukemia cells.
Topics: Acetamides; Animals; Cell Differentiation; Cell Line; Dimethyl Sulfoxide; Heme; Kinetics; Leukemia, | 1987 |
Inhibition by bryostatin 1 of the phorbol ester-induced blockage of differentiation in hexamethylene bisacetamide-treated Friend erythroleukemia cells.
Topics: Acetamides; Animals; Antineoplastic Agents; Bryostatins; Carcinogens; Cell Differentiation; Cell Lin | 1987 |
Contributions of transcriptional and post-transcriptional mechanisms to the regulation of c-myc expression in mouse erythroleukemia cells.
Topics: Acetamides; Animals; Cell Differentiation; Cell Line; Dactinomycin; Gene Expression Regulation; Kine | 1987 |
Changes in gene expression during hexamethylene bisacetamide induced erythroleukemia differentiation.
Topics: Acetamides; Animals; Cell Differentiation; Cell Line; Gene Expression Regulation; Genes; Globins; Ki | 1987 |
Analysis of the growth kinetics of murine erythroleukaemia cells following commitment to terminal differentiation.
Topics: Acetamides; Animals; Cell Cycle; Cell Differentiation; Leukemia, Erythroblastic, Acute; Mice; Time F | 1987 |
Transfection of mouse erythroleukemia cells with myc sequences changes the rate of induced commitment to differentiate.
Topics: Acetamides; Animals; Cell Differentiation; Cell Line; Cloning, Molecular; Gene Expression Regulation | 1986 |
Sequential alterations in globin gene chromatin structure during erythroleukemia cell differentiation.
Topics: Acetamides; Animals; Cell Differentiation; Cell Line; Chromatin; Deoxyribonuclease I; Globins; Imida | 1985 |
Gene expression during terminal differentiation: dexamethasone suppression of inducer-mediated alpha 1- and beta maj-globin gene expression.
Topics: Acetamides; Animals; Cell Differentiation; Cell Division; Cell Line; Chromatin; Dexamethasone; Gene | 1985 |
Amiloride in differentiation and commitment of Friend erythroleukemia cells.
Topics: Acetamides; Amiloride; Animals; Benzidines; Cell Differentiation; Cell Division; Cell Line; Dimethyl | 1985 |
The proportions of hemoglobin types induced in mouse erythroleukemia cells vary with the inducer or combination of inducers, the inducer concentration and the time of induction.
Topics: Acetamides; Animals; Cell Differentiation; Cell Line; Dimethyl Sulfoxide; Drug Synergism; Erythropoi | 1985 |