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hexamethylene bisacetamide and Glioma

hexamethylene bisacetamide has been researched along with Glioma in 4 studies

N,N'-diacetyl-1,6-diaminohexane: chemical name obtained from Acta Biol Hung 1990;41(1-3):199-208

Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)

Research Excerpts

ExcerptRelevanceReference
"The modulation effects of hexamethylene bisacetamide (HMBA), a differentiation-inducing agent, on growth and differentiation of cells from human malignant glioma cell line SHG-44 were studied."7.69Modulation effects of hexamethylene bisacetamide on growth and differentiation of cultured human malignant glioma cells. ( Du, ZW; Huang, Q; Li, XN, 1996)
"Hexamethylene bisacetamide (HMBA)-induced growth inhibition and differentiation of the rat C6 glioma cell line were found to be accompanied by down-regulation of the constitutively expressed fra-1 gene."3.72Overexpression of the immediate early gene fra-1 inhibits proliferation, induces apoptosis, and reduces tumourigenicity of c6 glioma cells. ( Shaikh, SA; Shirsat, NV, 2003)
"The modulation effects of hexamethylene bisacetamide (HMBA), a differentiation-inducing agent, on growth and differentiation of cells from human malignant glioma cell line SHG-44 were studied."3.69Modulation effects of hexamethylene bisacetamide on growth and differentiation of cultured human malignant glioma cells. ( Du, ZW; Huang, Q; Li, XN, 1996)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's2 (50.00)29.6817
2010's0 (0.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Funck-Brentano, E1
Vizlin-Hodzic, D1
Nilsson, JA1
Nilsson, LM1
Shirsat, NV2
Shaikh, SA1
Li, XN1
Du, ZW1
Huang, Q1
Kayal, JJ1
Shaikh, S1
Mehta, A1

Other Studies

4 other studies available for hexamethylene bisacetamide and Glioma

ArticleYear
BET bromodomain inhibitor HMBA synergizes with MEK inhibition in treatment of malignant glioma.
    Epigenetics, 2021, Volume: 16, Issue:1

    Topics: Acetamides; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosi

2021
Overexpression of the immediate early gene fra-1 inhibits proliferation, induces apoptosis, and reduces tumourigenicity of c6 glioma cells.
    Experimental cell research, 2003, Nov-15, Volume: 291, Issue:1

    Topics: Acetamides; Animals; Antineoplastic Agents; Apoptosis; Astrocytoma; Brain Neoplasms; Bucladesine; Ce

2003
Modulation effects of hexamethylene bisacetamide on growth and differentiation of cultured human malignant glioma cells.
    Journal of neurosurgery, 1996, Volume: 84, Issue:5

    Topics: Acetamides; Adult; Antineoplastic Agents; Brain Neoplasms; Cell Differentiation; Cell Line; Dose-Res

1996
Growth inhibition and differentiation of C6 glioma cells on treatment with hmba.
    Cell biology international, 2001, Volume: 25, Issue:7

    Topics: Acetamides; Antineoplastic Agents; Brain Neoplasms; Cell Cycle; Cell Differentiation; Cell Division;

2001