hexamethylene bisacetamide has been researched along with Experimental Leukemia in 55 studies
N,N'-diacetyl-1,6-diaminohexane: chemical name obtained from Acta Biol Hung 1990;41(1-3):199-208
Excerpt | Relevance | Reference |
---|---|---|
"Friend murine erythroleukemia cell lines derive from erythroblasts transformed with the Friend complex where the spleen-focus forming virus integrated in the vicinity of the Sfpi-1 locus." | 1.35 | PU.1 is dispensable to block erythroid differentiation in Friend erythroleukemia cells. ( Fernández-Nestosa, MJ; Hernández, P; Krimer, DB; Schvartzman, JB, 2008) |
"Murine erythroleukemia cells rendered deficient in cAMP-dependent protein kinase (A-kinase) activity by gene transfection are severely impaired in hexamethylene bisacetamide (HMBA)-induced differentiation (Pilz, R." | 1.29 | Impaired erythroid-specific gene expression in cAMP-dependent protein kinase-deficient murine erythroleukemia cells. ( Pilz, RB, 1993) |
"Following treatment of mouse erythroleukemia (MEL) cells with dimethyl sulfoxide and other typical erythroid inducing agents, the profile of cellular phosphotyrosine-containing proteins was drastically altered." | 1.28 | Alteration of phosphotyrosine-containing proteins at the early stage of erythroid differentiation of mouse erythroleukemia (MEL) cells. ( Kume, T; Oishi, M; Watanabe, T, 1992) |
"The induction of murine erythroleukemia cells (MELC; DS19/Sc9) to terminal differentiation by hexamethylenebisacetamide (HMBA) is characterized by a latent period of 10-12 hr before onset of commitment to terminal-cell division and increased transcription of globin genes." | 1.28 | Characteristics of erythroleukemia cells selected for vincristine resistance that have accelerated inducer-mediated differentiation. ( Kiyokawa, H; Leng, L; Marks, PA; Ngo, L; Richon, VM; Rifkind, RA; Weich, N, 1991) |
"Hexamethylene bisacetamide (HMBA) is a potent inducer of differentiation of murine erythroleukemia cells (MELC)." | 1.28 | Conversion of differentiation inducer resistance to differentiation inducer sensitivity in erythroleukemia cells. ( Chen, ZX; Lebedev, YB; Marks, PA; Michaeli, J; Richon, VM; Rifkind, RA, 1990) |
"Induction of differentiation in murine erythroleukemia cells (MELCs) involves a protein kinase C (PKC)-mediated step." | 1.28 | Introduction of the beta isozyme of protein kinase C accelerates induced differentiation of murine erythroleukemia cells. ( Grossi, F; Marks, PA; Melloni, E; Patrone, M; Pontremoli, S; Rifkind, RA; Sparatore, B, 1990) |
" Despite such a down regulation of phorbol ester receptors, these cells respond to PMA with a dose-response similar to that of their parent cells, which have the normal number of phorbol ester receptors." | 1.27 | Continuous suppression of globin gene expression and differentiation of Friend erythroleukemia cells by phorbol 12-myristate 13-acetate (PMA) despite the loss of PMA binding sites by down regulation. ( Fusco, A; Martel, N; Ostertag, W; Yamasaki, H, 1984) |
"The state of DNA methylation in mouse erythroleukemia (MEL) cells has been analyzed in relation to commitment to differentiation in response to treatment with hexamethylenebisacetamide (HMBA)." | 1.27 | Relationship between transient DNA hypomethylation and erythroid differentiation of murine erythroleukemia cells. ( Agostini, S; Cantoni, GL; Gomi, T; Kafri, T; Levine, A; Razin, A, 1988) |
"Friend erythroleukemia cells were induced to differentiate by dimethyl sulfoxide (DMSO) and hexamethylene-bis-acetamide (HBMA) in order to investigate whether their lipid characteristics, common to other systems of transformed cells, revert to a normal differentiation pattern." | 1.27 | Lipid changes associated with erythroid differentiation of Friend erythroleukemia cells. ( Arcangeli, A; Fallani, A; Ruggieri, S, 1987) |
"Friend virus-transformed murine erythroleukemia cells express the program of erythropoietic differentiation under the influence of the previously described, potent inducing agent, hexamethylene bisacetamide." | 1.26 | Effect of hexamethylene bisacetamide on the commitment to differentiation of murine erythroleukemia cells. ( Fibach, E; Marks, PA; Reuben, RC; Rifkind, RA, 1977) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 41 (74.55) | 18.7374 |
1990's | 13 (23.64) | 18.2507 |
2000's | 1 (1.82) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Fernández-Nestosa, MJ | 1 |
Hernández, P | 1 |
Schvartzman, JB | 1 |
Krimer, DB | 1 |
Gazitt, Y | 1 |
Friend, C | 1 |
Sheffery, M | 3 |
Rifkind, RA | 13 |
Marks, PA | 13 |
Flickinger, RA | 1 |
Richman, R | 1 |
Schmitt, H | 1 |
Guyaux, M | 1 |
Pochet, R | 1 |
Kram, R | 1 |
Mechti, N | 1 |
Affabris, E | 1 |
Romeo, G | 1 |
Lebleu, B | 1 |
Rossi, GB | 1 |
Yamasaki, H | 4 |
Martel, N | 2 |
Fusco, A | 1 |
Ostertag, W | 1 |
Shen, DW | 1 |
Real, FX | 1 |
DeLeo, AB | 1 |
Old, LJ | 1 |
Billard, C | 2 |
Billard, M | 1 |
Mishal, Z | 2 |
Gambari, R | 5 |
Giri, JG | 1 |
Reuben, RC | 2 |
Morioka, K | 3 |
Tanaka, K | 3 |
Ono, T | 3 |
Osborne, HB | 1 |
Suthanthiran, M | 1 |
Rubin, AL | 1 |
Novogrodsky, A | 1 |
Stenzel, KH | 1 |
Di Girolamo, A | 1 |
Di Girolamo, M | 1 |
Lacatena, RM | 1 |
Nasi, S | 1 |
Chen, ZX | 2 |
Banks, J | 1 |
Zwingelstein, G | 1 |
Tapiero, H | 3 |
Portoukalian, J | 1 |
Fourcade, A | 3 |
Farace, M | 1 |
Fantoni, A | 1 |
Asami, Y | 1 |
Saheki, S | 1 |
Harada-Saheki, K | 1 |
Tanaka, T | 1 |
Wirth, PJ | 1 |
Reinhold, CE | 1 |
Thorgeirsson, SS | 1 |
Fibach, E | 3 |
Saint-Vincent, L | 1 |
Kume, T | 2 |
Tsuneizumi, K | 1 |
Watanabe, T | 2 |
Thomas, ML | 1 |
Oishi, M | 2 |
Hayashi, M | 1 |
Pilz, RB | 1 |
Arcangeli, A | 3 |
Carlà, M | 1 |
Del Bene, MR | 1 |
Becchetti, A | 1 |
Wanke, E | 1 |
Olivotto, M | 1 |
Constantinou, AI | 1 |
Vaughan, AT | 1 |
Kamath, N | 1 |
Nudel, U | 1 |
Weinstein, IB | 1 |
Mencherini, F | 1 |
Khochbin, S | 2 |
Chabanas, A | 1 |
Lawrence, JJ | 2 |
Richon, VM | 2 |
Weich, N | 1 |
Leng, L | 1 |
Kiyokawa, H | 1 |
Ngo, L | 1 |
Tonetti, M | 1 |
Gasparini, A | 1 |
Giovine, M | 1 |
Benatti, U | 1 |
De Flora, A | 1 |
Sala, A | 1 |
Benedetto, A | 1 |
Elia, G | 1 |
Pulciani, S | 1 |
Ciotta, C | 1 |
Parlanti, E | 1 |
Santodonato, L | 1 |
Belardelli, F | 1 |
Michaeli, J | 1 |
Lebedev, YB | 1 |
Grunwald, D | 1 |
Melloni, E | 1 |
Pontremoli, S | 1 |
Sparatore, B | 1 |
Patrone, M | 1 |
Grossi, F | 1 |
Weidner, DA | 1 |
Winicov, I | 1 |
Beckman, BS | 1 |
Kopfler, W | 1 |
Koury, P | 1 |
Jeter, JR | 1 |
Brac, T | 1 |
Ebisuzaki, K | 1 |
Egorin, MJ | 1 |
Snyder, SW | 1 |
Cohen, AS | 1 |
Zuhowski, EG | 1 |
Subramanyam, B | 1 |
Callery, PS | 1 |
Razin, A | 1 |
Levine, A | 1 |
Kafri, T | 1 |
Agostini, S | 1 |
Gomi, T | 1 |
Cantoni, GL | 1 |
Fallani, A | 2 |
Ruggieri, S | 2 |
DiMambro, E | 1 |
Galanti, M | 1 |
Levy, SB | 1 |
Dell'Aquila, ML | 1 |
Nguyen, HT | 1 |
Herald, CL | 1 |
Pettit, GR | 1 |
Blumberg, PM | 1 |
Nepveu, A | 1 |
Marcu, KB | 1 |
Skoultchi, AI | 1 |
Lachman, HM | 1 |
Ramsay, R | 1 |
Lubin, M | 1 |
2 reviews available for hexamethylene bisacetamide and Experimental Leukemia
Article | Year |
---|---|
[Experimental model for differentiation therapy of leukemia].
Topics: Acetamides; Animals; Antineoplastic Agents; Cell Differentiation; DNA, Neoplasm; Flow Cytometry; Leu | 1993 |
Induced erythroleukemia differentiation: cellular and molecular aspects.
Topics: Acetamides; Animals; Calcium; Cell Differentiation; Diglycerides; Gene Expression Regulation; Globin | 1987 |
53 other studies available for hexamethylene bisacetamide and Experimental Leukemia
Article | Year |
---|---|
PU.1 is dispensable to block erythroid differentiation in Friend erythroleukemia cells.
Topics: Acetamides; Animals; Azacitidine; Cell Differentiation; Decitabine; Drug Resistance; Erythroid Cells | 2008 |
Polyamine biosynthesis enzymes in the induction and inhibition of differentiation in Friend erythroleukemia cells.
Topics: Acetamides; Animals; Butyrates; Carboxy-Lyases; Cell Differentiation; Dexamethasone; Diamines; Dimet | 1980 |
Hexamethylenebisacetamide-resistant murine erythroleukemia cells have altered patterns of inducer-mediated chromatin changes.
Topics: Acetamides; Animals; Cell Line; Chromatin; Deoxyribonuclease I; Drug Resistance; Endodeoxyribonuclea | 1983 |
The effect of induction of hemoglobin synthesis in cultured Friend cells on the number of initiation sites for replication and transcription.
Topics: Acetamides; Aminoisobutyric Acids; Animals; Cell Differentiation; Cell Line; Dimethyl Sulfoxide; DNA | 1984 |
Induction and properties of beta-adrenergic receptors during erythroid differentiation of Friend leukemic cells.
Topics: Acetamides; Animals; Butyrates; Cell Differentiation; Dexamethasone; Diamines; Dimethyl Sulfoxide; E | 1980 |
Role of interferon and 2',5'-oligoadenylate synthetase in erythroid differentiation of Friend leukemia cells. Studies with interferon-sensitive and -resistant variants.
Topics: 2',5'-Oligoadenylate Synthetase; Acetamides; Animals; Cell Differentiation; Cell Line; Enzyme Induct | 1984 |
Continuous suppression of globin gene expression and differentiation of Friend erythroleukemia cells by phorbol 12-myristate 13-acetate (PMA) despite the loss of PMA binding sites by down regulation.
Topics: Acetamides; Animals; Caenorhabditis elegans Proteins; Carrier Proteins; Cell Differentiation; Cell L | 1984 |
Protein p53 and inducer-mediated erythroleukemia cell commitment to terminal cell division.
Topics: Acetamides; Animals; Antibodies, Monoclonal; Antigens, Neoplasm; Antigens, Surface; Cell Cycle; Cell | 1983 |
Effects of differentiation inducers on diphenylhexatriene fluorescence polarization in intracytoplasmic and plasma membranes from Friend erythroleukemia cells.
Topics: Acetamides; Animals; Cell Differentiation; Cell Line; Cell Membrane; Clone Cells; Dimethyl Sulfoxide | 1983 |
Hexamethylenebisacetamide-mediated induction of murine erythroleukemia cells: relationship between expression of beta major and beta minor globin genes, globin mRNA synthesis and commitment to erythroid differentiation.
Topics: Acetamides; Animals; Carrier Proteins; Cell Differentiation; Dexamethasone; DNA-Binding Proteins; Ge | 1983 |
[Commitment to erythroid differentiation and globin gene expression in the absence of heme accumulation in Friend leukemia cells].
Topics: Acetamides; Animals; Cell Differentiation; Electrophoresis, Cellulose Acetate; Flow Cytometry; Frien | 1983 |
DNA polymerase activities during induced differentiation in murine erythroleukemia cells.
Topics: Acetamides; Animals; Cell Cycle; Cell Differentiation; Cell Division; Cell Separation; Cells, Cultur | 1981 |
Comparison of nuclear proteins of differentiation-induced and uninduced Friend erythroleukemia cells.
Topics: Acetamides; Animals; Cell Differentiation; Cell Nucleus; Chromosomal Proteins, Non-Histone; Diamines | 1981 |
Comparison of dexamethasone binding and resistance to inhibition of induced differentiation in subclones of murine erythroleukemia cells.
Topics: Acetamides; Animals; Cell Differentiation; Clone Cells; Dexamethasone; Diamines; Drug Resistance; Le | 1981 |
Immunosuppressive properties of polar organic compounds that induce cellular differentiation in Friend erythroleukemia cells.
Topics: 3-Hydroxybutyric Acid; Acetamides; Adult; Animals; Butyrates; Cell Transformation, Neoplastic; Cytot | 1982 |
An HMBA-resistant and heme-synthesizing variant clone of Friend leukemia cells.
Topics: Acetamides; Animals; Cell Division; Cell Line; Clone Cells; Diamines; Dimethyl Sulfoxide; Erythropoi | 1982 |
Differential effect of dexamethasone on Friend leukemia cells induced to differentiate by hexamethylenebisacetamide or butyric acid.
Topics: Acetamides; Animals; Butyrates; Cell Differentiation; Cells, Cultured; Dexamethasone; Diamines; Frie | 1982 |
Commitment: a multi-step process during induced MELC differentiation.
Topics: Acetamides; Animals; Carcinogens; Cell Differentiation; Cell Nucleus; Cytoplasm; Dexamethasone; Gene | 1982 |
Changes in phospholipid and fatty acid composition in differentiated Friend leukaemic cells.
Topics: Acetamides; Animals; Butyrates; Cell Differentiation; Cells, Cultured; Cholesterol; Diamines; Dimeth | 1981 |
The effect of hexamethylene-bis-acetamide on multiparameter analysis of Friend leukemia cells.
Topics: Acetamides; Animals; Cell Differentiation; Cell Line; Cell Membrane; Cell Separation; Dexamethasone; | 1981 |
Expression of erythroid differentiation and terminal cell division in induced Friend leukemia cells.
Topics: Acetamides; Animals; Cell Differentiation; Cell Division; Cell Line; Clone Cells; Diamines; Genes; G | 1981 |
Isozyme patterns of pyruvate kinase and differentiation of Friend leukemia cells.
Topics: Acetamides; Animals; Cell Differentiation; Cell Line; Diamines; Enzyme Induction; Erythrocytes; Frie | 1980 |
Inhibition of chemically induced erythrodifferentiation in Friends erythroleukemia cells by d,1-propranolol.
Topics: Acetamides; Animals; Butyrates; Cell Differentiation; Cell Line; Diamines; Dimethyl Sulfoxide; Dose- | 1980 |
Inhibition of induced murine erythroleukemia cell differentiation by tumor promoters: relation to the cell cycle.
Topics: Acetamides; Animals; Cell Cycle; Cell Differentiation; Diamines; DNA, Neoplasm; Globins; Kinetics; L | 1980 |
Membrane dynamics of Friend leukaemic cells. II. Changes associated with cell differentiation.
Topics: Acetamides; Animals; Cell Differentiation; Cell Membrane; Cells, Cultured; Diamines; Dimethyl Sulfox | 1980 |
Poly(ADP-ribose) and differentiation of Friend Erythroleukemia cells. Restriction of the chain lenght.
Topics: Acetamides; Animals; Cell Differentiation; Cell Line; Diamines; Leukemia, Experimental; Male; Mice; | 1980 |
Long-term effect of a tumor promoter, 12-O-tetradecanoylphorbol-13-acetate, on induced differentiation of Friend leukemia cells.
Topics: Acetamides; Animals; Cell Differentiation; Cells, Cultured; Cocarcinogenesis; Diamines; Friend murin | 1980 |
Induction of specific protein tyrosine phosphatase transcripts during differentiation of mouse erythroleukemia cells.
Topics: Acetamides; Animals; Blotting, Northern; Cell Differentiation; Cell Line; DNA Probes; Enzyme Inducti | 1994 |
Impaired erythroid-specific gene expression in cAMP-dependent protein kinase-deficient murine erythroleukemia cells.
Topics: 5-Aminolevulinate Synthetase; Acetamides; Aminolevulinic Acid; Animals; Blotting, Northern; Cell Dif | 1993 |
Polar/apolar compounds induce leukemia cell differentiation by modulating cell-surface potential.
Topics: Acetamides; Animals; Antineoplastic Agents; Cell Differentiation; Cell Membrane; Chlorides; Dimethyl | 1993 |
Commitment to erythroid differentiation in mouse erythroleukemia cells is controlled by alterations in topoisomerase II alpha phosphorylation.
Topics: Acetamides; Animals; Antigens, Neoplasm; Antineoplastic Agents; Cell Differentiation; Cell Nucleus; | 1996 |
Effect of hexamethylene bisacetamide on the commitment to differentiation of murine erythroleukemia cells.
Topics: Acetamides; Animals; Cell Differentiation; Cell Division; Clone Cells; Dimethyl Sulfoxide; DNA, Neop | 1977 |
Tumor promoters inhibit spontaneous and induced differentiation of murine erythroleukemia cells in culture.
Topics: Acetamides; Animals; Carcinogens; Cell Differentiation; Cell Division; Cell Line; Diamines; Dose-Res | 1977 |
Alteration of phosphotyrosine-containing proteins at the early stage of erythroid differentiation of mouse erythroleukemia (MEL) cells.
Topics: Acetamides; Animals; Antineoplastic Agents; Butyrates; Butyric Acid; Cell Differentiation; Cell Line | 1992 |
Seric factors influence cell cycle modifications during commitment of murine erythroleukemia cells to differentiation.
Topics: Acetamides; Animals; Biomarkers, Tumor; Blood Proteins; Blotting, Northern; Butyrates; Cell Cycle; C | 1992 |
Characteristics of erythroleukemia cells selected for vincristine resistance that have accelerated inducer-mediated differentiation.
Topics: Acetamides; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; | 1991 |
Enhanced intracellular activation of carboplatin in hemoglobin-synthesizing versus undifferentiated erythroleukemic cells.
Topics: Acetamides; Animals; Carboplatin; Cell Differentiation; Cell Survival; Cisplatin; DNA, Neoplasm; Hem | 1992 |
Growth properties, differentiation capacity and oncogene expression in metastatic and nonmetastatic Friend leukemia cell variants.
Topics: Acetamides; Animals; Cell Differentiation; Cell Division; Dimethyl Sulfoxide; Friend murine leukemia | 1991 |
Conversion of differentiation inducer resistance to differentiation inducer sensitivity in erythroleukemia cells.
Topics: Acetamides; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Differentiation; | 1990 |
Cell cycle-related accumulation of H1(0) mRNA: induction in murine erythroleukemia cells.
Topics: Acetamides; Animals; Cell Cycle; Cell Line; Clone Cells; DNA Probes; Hematinics; Histones; Kinetics; | 1991 |
Introduction of the beta isozyme of protein kinase C accelerates induced differentiation of murine erythroleukemia cells.
Topics: Acetamides; Animals; Brain; Cell Differentiation; Cell Line; Drug Resistance; Isoenzymes; Kinetics; | 1990 |
Beta globin gene transcripts originating in the promoter region during early hexamethylene bisacetamide and dimethylsulfoxide induction of Friend erythroleukemia cells.
Topics: Acetamides; Cell Line; Dimethyl Sulfoxide; Friend murine leukemia virus; Gene Expression Regulation; | 1989 |
Effect of aphidicolin on Friend erythroleukemia cell maturation.
Topics: Acetamides; Animals; Aphidicolin; Cell Differentiation; Cell Division; Diterpenes; DNA Polymerase II | 1987 |
PolyADP ribosylation and Friend erythroleukemic-cell differentiation: action of poly(ADP-ribose) polymerase inhibitors.
Topics: Acetamides; Animals; Benzamides; Cell Differentiation; Cell Division; Cell Line; Dimethyl Sulfoxide; | 1987 |
Metabolism of hexamethylene bisacetamide and its metabolites in leukemic cells.
Topics: Acetamides; Animals; Humans; Leukemia L1210; Leukemia P388; Leukemia, Experimental; Leukemia, Myeloi | 1988 |
Relationship between transient DNA hypomethylation and erythroid differentiation of murine erythroleukemia cells.
Topics: Acetamides; Animals; Cell Differentiation; Cell Line; Cycloheximide; DNA, Neoplasm; Isomerism; Kinet | 1988 |
Lipid characteristics of Friend erythroleukaemia cells differentiated by dimethyl sulphoxide or hexamethylenebisacetamide, and of non-inducible clones treated with the inducers.
Topics: Acetamides; Cell Differentiation; Cell Line; Clone Cells; Dimethyl Sulfoxide; Fatty Acids; Friend mu | 1988 |
Lipid changes associated with erythroid differentiation of Friend erythroleukemia cells.
Topics: Acetamides; Animals; Cell Differentiation; Cell Line; Cholesterol; Dimethyl Sulfoxide; Fatty Acids, | 1987 |
Precommitted erythroid cells enriched in cultures of suboptimally induced Friend erythroleukemia cells.
Topics: Acetamides; Animals; Cell Differentiation; Cell Line; Dimethyl Sulfoxide; Heme; Kinetics; Leukemia, | 1987 |
Inhibition by bryostatin 1 of the phorbol ester-induced blockage of differentiation in hexamethylene bisacetamide-treated Friend erythroleukemia cells.
Topics: Acetamides; Animals; Antineoplastic Agents; Bryostatins; Carcinogens; Cell Differentiation; Cell Lin | 1987 |
Contributions of transcriptional and post-transcriptional mechanisms to the regulation of c-myc expression in mouse erythroleukemia cells.
Topics: Acetamides; Animals; Cell Differentiation; Cell Line; Dactinomycin; Gene Expression Regulation; Kine | 1987 |
Changes in gene expression during hexamethylene bisacetamide induced erythroleukemia differentiation.
Topics: Acetamides; Animals; Cell Differentiation; Cell Line; Gene Expression Regulation; Genes; Globins; Ki | 1987 |
Amiloride in differentiation and commitment of Friend erythroleukemia cells.
Topics: Acetamides; Amiloride; Animals; Benzidines; Cell Differentiation; Cell Division; Cell Line; Dimethyl | 1985 |