hexamethylene bisacetamide has been researched along with Colonic Neoplasms in 11 studies
N,N'-diacetyl-1,6-diaminohexane: chemical name obtained from Acta Biol Hung 1990;41(1-3):199-208
Colonic Neoplasms: Tumors or cancer of the COLON.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The differentiation agent hexamethylene bisacetamide (HMBA) increased expression of transforming growth factor beta 1 (TGF beta 1) mRNA in HT29 colon carcinoma cells." | 7.68 | Role of transforming growth factor beta 1 in induction of colon carcinoma differentiation by hexamethylene bisacetamide. ( Coffey, RJ; Friedman, E; Rifkin, J; Schroy, P; Winawer, S, 1990) |
| "The role of transforming growth factor beta 1 (TGF-beta 1) in enterocytic differentiation was examined by treating two undifferentiated HT29 colon carcinoma sublines, U4 and U9, with hexamethylene bisacetamide to up-regulate their level of TGF-beta 1 mRNA expression." | 3.68 | Two roles for transforming growth factor beta 1 in colon enterocytic cell differentiation. ( Friedman, E; Hafez, MM; Hsu, S; Winawer, S; Yan, Z, 1992) |
| "The differentiation agent hexamethylene bisacetamide (HMBA) increased expression of transforming growth factor beta 1 (TGF beta 1) mRNA in HT29 colon carcinoma cells." | 3.68 | Role of transforming growth factor beta 1 in induction of colon carcinoma differentiation by hexamethylene bisacetamide. ( Coffey, RJ; Friedman, E; Rifkin, J; Schroy, P; Winawer, S, 1990) |
| " HMBA also induced HT29 cells to lose the capacity for anchorage-independent growth with a similar dose-response curve and time course to the loss of 29-15 epitope." | 1.27 | Heterogeneous responses of human colon carcinomas to hexamethylene bisacetamide. ( Carnright, K; Friedman, EA; Schroy, PC; Winawer, SJ, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (27.27) | 18.7374 |
| 1990's | 6 (54.55) | 18.2507 |
| 2000's | 2 (18.18) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schroy, PC | 2 |
| Rustgi, AK | 1 |
| Ikonomu, E | 1 |
| Liu, XP | 1 |
| Polito, J | 1 |
| Andry, C | 1 |
| O'Keane, JC | 1 |
| Zhang, Z | 1 |
| Liong, EC | 1 |
| Lau, TY | 1 |
| Leung, KM | 1 |
| Fung, PC | 1 |
| Tipoe, GL | 1 |
| Marilley, D | 1 |
| Vonlanthen, S | 1 |
| Gioria, A | 1 |
| Schwaller, B | 1 |
| Hafez, MM | 2 |
| Hsu, S | 1 |
| Yan, Z | 1 |
| Winawer, S | 4 |
| Friedman, E | 4 |
| Choi, PM | 1 |
| Weinstein, IB | 1 |
| Infante, D | 1 |
| Schroy, P | 2 |
| Rifkin, J | 1 |
| Coffey, RJ | 1 |
| Bill, CA | 1 |
| Vines, CM | 1 |
| Garrett, KC | 1 |
| Yamada, K | 1 |
| Tofilon, PJ | 1 |
| Friedman, J | 1 |
| Seger, M | 1 |
| Levinsky, H | 1 |
| Allalouf, D | 1 |
| Carnright, K | 1 |
| Winawer, SJ | 1 |
| Friedman, EA | 1 |
11 other studies available for hexamethylene bisacetamide and Colonic Neoplasms
| Article | Year |
|---|---|
Growth and intestinal differentiation are independently regulated in HT29 colon cancer cells.
Topics: Acetamides; Antineoplastic Agents; Biomarkers; Butyrates; Butyric Acid; Cell Differentiation; Cell D | 1994 |
Induction of apoptosis by hexamethylene bisacetamide is p53-dependent associated with telomerase activity but not with terminal differentiation.
Topics: Acetamides; Alkaline Phosphatase; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Differentiation | 2000 |
Calretinin and calretinin-22k increase resistance toward sodium butyrate-induced differentiation in CaCo-2 colon adenocarcinoma cells.
Topics: Acetamides; Adenocarcinoma; Antineoplastic Agents; Butyrates; Caco-2 Cells; Calbindin 2; Cell Cycle; | 2001 |
Two roles for transforming growth factor beta 1 in colon enterocytic cell differentiation.
Topics: Acetamides; Carcinoembryonic Antigen; Carcinoma; Cell Adhesion; Cell Differentiation; Colon; Colonic | 1992 |
The modulation of growth by HMBA in PKC overproducing HT29 colon cancer cells.
Topics: Acetamides; Cell Division; Colonic Neoplasms; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor | 1991 |
Transforming growth factor beta 1 acts as an autocrine-negative growth regulator in colon enterocytic differentiation but not in goblet cell maturation.
Topics: Acetamides; Cell Differentiation; Clone Cells; Colon; Colonic Neoplasms; Growth Inhibitors; Humans; | 1990 |
Role of transforming growth factor beta 1 in induction of colon carcinoma differentiation by hexamethylene bisacetamide.
Topics: Acetamides; Biomarkers, Tumor; Carcinoma; Cell Differentiation; Colonic Neoplasms; Humans; RNA, Mess | 1990 |
Enhancement of the radiosensitivity of two human tumour cell lines by hexamethylene bisacetamide.
Topics: Acetamides; Adenocarcinoma; Cell Line; Cell Survival; Colonic Neoplasms; Humans; Radiation Tolerance | 1990 |
Modulation of carcinoembryonic antigen release by HT-29 colon carcinoma line in the presence of different agents.
Topics: Acetamides; Azacitidine; Butyrates; Butyric Acid; Carcinoembryonic Antigen; Cell Differentiation; Co | 1987 |
Heterogeneous responses of human colon carcinomas to hexamethylene bisacetamide.
Topics: Acetamides; Biomarkers, Tumor; Cell Division; Colonic Neoplasms; Epitopes; Humans; Tumor Cells, Cult | 1988 |
Effect on in vivo tumorigenicity of lengthy exposure of human colon cancer cells to the differentiation agent hexamethylene bisacetamide.
Topics: Acetamides; Animals; Antibodies, Monoclonal; Antigens, Neoplasm; Biomarkers, Tumor; Colonic Neoplasm | 1989 |