hexamethylene bisacetamide has been researched along with Carcinoma, Hepatocellular in 8 studies
N,N'-diacetyl-1,6-diaminohexane: chemical name obtained from Acta Biol Hung 1990;41(1-3):199-208
Carcinoma, Hepatocellular: A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the cellular effects of hybrid polar compound hexamethylene bisacetamide (HMBA) on the growth and apoptosis of human hepatocellular carcinoma cells and to provide the molecular mechanism for potential application of HMBA in the treatment of liver cancer." | 7.72 | Growth arrest and apoptosis of human hepatocellular carcinoma cells induced by hexamethylene bisacetamide. ( Bao, SD; Cai, QF; Chen, F; Chen, RC; Hong, SG; Huang, Z; Jiang, RS; Liu, M; Ouyang, GL, 2004) |
| "To investigate the cellular effects of hybrid polar compound hexamethylene bisacetamide (HMBA) on the growth and apoptosis of human hepatocellular carcinoma cells and to provide the molecular mechanism for potential application of HMBA in the treatment of liver cancer." | 3.72 | Growth arrest and apoptosis of human hepatocellular carcinoma cells induced by hexamethylene bisacetamide. ( Bao, SD; Cai, QF; Chen, F; Chen, RC; Hong, SG; Huang, Z; Jiang, RS; Liu, M; Ouyang, GL, 2004) |
| " In this study, we combined the effects of the differentiation agent hexamethylene bisacetamide and the inhibiting effects of TGF-B1 on a multidrug-resistant human liver hepatocellular carcinoma and demonstrated the synergistic interaction of these two agents; this synergy resulted in a cell death rate of 80%." | 3.68 | Cytoreductive therapy of multidrug-resistant hepatocellular carcinoma: negative regulation of growth using combination differentiation therapy. ( Ades, EW; Hooper, C; Pruckler, JM, 1992) |
| "Mitomycin was used in 40 patients and dihydroxyanthracenedione (DADH) in 58 patients." | 2.67 | [The treatment of hepatocellular carcinoma by chemoembolization]. ( Bortolasi, L; Dal Dosso, I; Facci, E; Mansueto, GC; Marchiori, L; Nicoli, N; Nifosi, F; Perus, G, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, QF | 4 |
| Tang, J | 2 |
| Liu, QR | 1 |
| Shi, SL | 1 |
| Chen, XF | 1 |
| Ouyang, GL | 3 |
| Peng, XX | 2 |
| Hong, SG | 3 |
| Cai, QF | 1 |
| Liu, M | 1 |
| Chen, RC | 1 |
| Huang, Z | 1 |
| Jiang, RS | 1 |
| Chen, F | 1 |
| Bao, SD | 1 |
| Niu, JW | 1 |
| Xu, DH | 1 |
| Li, ZX | 1 |
| Chen, JA | 1 |
| Ades, EW | 1 |
| Hooper, C | 1 |
| Pruckler, JM | 1 |
| Marchiori, L | 2 |
| Mansueto, GC | 2 |
| Nifosi, F | 1 |
| Bortolasi, L | 2 |
| Dal Dosso, I | 2 |
| Facci, E | 1 |
| Perus, G | 1 |
| Nicoli, N | 2 |
| Morana, G | 1 |
| Bellini, A | 1 |
| Musajo, F | 1 |
| Costa, V | 1 |
| Pederzoli, P | 1 |
1 trial available for hexamethylene bisacetamide and Carcinoma, Hepatocellular
| Article | Year |
|---|---|
[The treatment of hepatocellular carcinoma by chemoembolization].
Topics: Acetamides; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Hepatocellular; Chemoe | 1994 |
7 other studies available for hexamethylene bisacetamide and Carcinoma, Hepatocellular
| Article | Year |
|---|---|
Localization and altered expression of nucleophosmin in the nuclear matrix during the differentiation of human hepatocarcinoma SMMC-7721 cells induced by HMBA.
Topics: Acetamides; Antineoplastic Agents; Blotting, Western; Carcinoma, Hepatocellular; Cell Differentiatio | 2010 |
[Differentiation of human hepatocarcinoma SMMC-7721 cells induced by HMBA].
Topics: Acetamides; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Differentiation; Cell Division; H | 2001 |
Growth arrest and apoptosis of human hepatocellular carcinoma cells induced by hexamethylene bisacetamide.
Topics: Acetamides; Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Cell Division; Cell Line, T | 2004 |
[Effects of HMBA on the expression of cell-cycle-associated genes in human hepatocarcinoma SMMC-7721 cells].
Topics: Acetamides; Carcinoma, Hepatocellular; Cell Cycle Proteins; Cell Differentiation; Cell Line, Tumor; | 2002 |
Alteration of nuclear matrix-intermediate filament system and differential expression of nuclear matrix proteins during human hepatocarcinoma cell differentiation.
Topics: Acetamides; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Differentiation; Cell Line, Tumor | 2007 |
Cytoreductive therapy of multidrug-resistant hepatocellular carcinoma: negative regulation of growth using combination differentiation therapy.
Topics: Acetamides; Carcinoma, Hepatocellular; Cell Death; Cell Differentiation; Cell Division; Doxorubicin; | 1992 |
Treatment of hepatocellular carcinoma.
Topics: Acetamides; Carcinoma, Hepatocellular; Catheterization; Chemoembolization, Therapeutic; Embolization | 1993 |