hexamethylene bisacetamide has been researched along with Breast Cancer in 6 studies
N,N'-diacetyl-1,6-diaminohexane: chemical name obtained from Acta Biol Hung 1990;41(1-3):199-208
| Excerpt | Relevance | Reference |
|---|---|---|
| "We have been studying the role of Hexamethylene bisacetamide (HMBA) Induced Protein 1 (HEXIM1) as a tumor suppressor whose expression is decreased in tamoxifen resistant and metastatic breast cancer." | 3.83 | Induction of HEXIM1 activities by HMBA derivative 4a1: Functional consequences and mechanism. ( Exner, A; Ketchart, W; Lathia, J; Montano, MM; Reizes, O; Su, B; Thiagarajan, PS; Yeh, IJ; Zhou, H, 2016) |
| "The effects of the differentiation inducing agents (DIAS), sodium butyrate (NaBu), retinoic acid (RA), dimethylformamide (DMF), hexamethylene bisacetamide (HMBA), forskolin, and 12-O-tetradecanoylphorbol-13-acetate (TPA), on the growth, morphology, and estrogen receptor (ER) content and epithelial membrane antigen (EMA) expression on a serumless human breast cancer cell line (MCF-7) were compared." | 3.68 | Effects of differentiation-inducing agents on maturation of human MCF-7 breast cancer cells. ( Dupont, MA; Gas, N; Guilbaud, NF; Valette, A, 1990) |
| "Hexamethylene Bisacetamide (HMBA) is a hybrid polar compound originally developed as a differentiation inducing agent." | 1.35 | Hexamethylene bisacetamide (HMBA) simultaneously targets AKT and MAPK pathway and represses NF kappaB activity: implications for cancer therapy. ( Dey, A; Kua, N; Lane, D; Teo, HL; Tergaonkar, V; Wong, E, 2008) |
| "Analysis of 43 invasive breast cancer samples and 40 adjacent normal breast samples demonstrated EDG1 protein levels to be significantly higher in normal breast epithelial tissue as compared with breast epithelial tumor tissue." | 1.32 | Identification of a novel inhibitor of breast cell growth that is down-regulated by estrogens and decreased in breast tumors. ( Montano, MM; Wang, N; Wittmann, BM, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ketchart, W | 1 |
| Yeh, IJ | 1 |
| Zhou, H | 1 |
| Thiagarajan, PS | 1 |
| Lathia, J | 1 |
| Reizes, O | 1 |
| Exner, A | 1 |
| Su, B | 2 |
| Montano, MM | 2 |
| Lama, R | 1 |
| Gan, C | 1 |
| Idippily, N | 1 |
| Bobba, V | 1 |
| Danielpour, D | 1 |
| Montano, M | 1 |
| Dey, A | 1 |
| Wong, E | 1 |
| Kua, N | 1 |
| Teo, HL | 1 |
| Tergaonkar, V | 1 |
| Lane, D | 1 |
| Chatterji, BP | 1 |
| Banerjee, M | 1 |
| Singh, P | 1 |
| Panda, D | 1 |
| Wittmann, BM | 1 |
| Wang, N | 1 |
| Guilbaud, NF | 1 |
| Gas, N | 1 |
| Dupont, MA | 1 |
| Valette, A | 1 |
6 other studies available for hexamethylene bisacetamide and Breast Cancer
| Article | Year |
|---|---|
Induction of HEXIM1 activities by HMBA derivative 4a1: Functional consequences and mechanism.
Topics: Acetamides; Animals; Antigens, Polyomavirus Transforming; Antineoplastic Agents; Benzeneacetamides; | 2016 |
HMBA is a putative HSP70 activator stimulating HEXIM1 expression that is down-regulated by estrogen.
Topics: Acetamides; Benzeneacetamides; Biotinylation; Breast Neoplasms; Cell Differentiation; Cell Line, Tum | 2017 |
Hexamethylene bisacetamide (HMBA) simultaneously targets AKT and MAPK pathway and represses NF kappaB activity: implications for cancer therapy.
Topics: Acetamides; Animals; Breast Neoplasms; Cell Death; Cell Line, Tumor; Cell Proliferation; Cell Surviv | 2008 |
HMBA depolymerizes microtubules, activates mitotic checkpoints and induces mitotic block in MCF-7 cells by binding at the colchicine site in tubulin.
Topics: Acetamides; Antineoplastic Agents; Binding Sites; Breast Neoplasms; Cell Line, Tumor; Colchicine; Fe | 2010 |
Identification of a novel inhibitor of breast cell growth that is down-regulated by estrogens and decreased in breast tumors.
Topics: Acetamides; Breast; Breast Neoplasms; Cell Division; Down-Regulation; Epithelial Cells; Estrogen Rec | 2003 |
Effects of differentiation-inducing agents on maturation of human MCF-7 breast cancer cells.
Topics: Acetamides; Antigens, Neoplasm; Breast Neoplasms; Butyrates; Butyric Acid; Cell Differentiation; Cel | 1990 |