Page last updated: 2024-10-28

hexamethonium and Vomiting

hexamethonium has been researched along with Vomiting in 8 studies

Hexamethonium: A nicotinic cholinergic antagonist often referred to as the prototypical ganglionic blocker. It is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier. It has been used for a variety of therapeutic purposes including hypertension but, like the other ganglionic blockers, it has been replaced by more specific drugs for most purposes, although it is widely used a research tool.

Vomiting: The forcible expulsion of the contents of the STOMACH through the MOUTH.

Research Excerpts

ExcerptRelevanceReference
" Erythromycin administration is associated with gastrointestinal problems, disturbed gastrointestinal motility and emesis."7.68Effects of cholinoceptor and 5-hydroxytryptamine3 receptor antagonism on erythromycin-induced canine intestinal motility disruption and emesis. ( Pilot, MA; Qin, XY; Scott, M; Thompson, H, 1993)
" Erythromycin administration is associated with gastrointestinal problems, disturbed gastrointestinal motility and emesis."3.68Effects of cholinoceptor and 5-hydroxytryptamine3 receptor antagonism on erythromycin-induced canine intestinal motility disruption and emesis. ( Pilot, MA; Qin, XY; Scott, M; Thompson, H, 1993)
"Vomiting, ear twitching and panting produced by either nicotine or dimethylphenylpiperazinium (DMPP) administered intracerebroventricularly (ICV) to the unanesthetized cat were studied and compared."3.66Central nicotinic receptors: vomiting, ear twitching and panting. ( Beleslin, DB; Dozić, S; Krstić, SK, 1983)
"Pretreatment with hexamethonium suppressed the cardiovascular response prior to retching and prolonged the latency to the first retching."1.31Role of the autonomic nervous system in emetic and cardiovascular responses in Suncus murinus. ( Ebukuro, S; Ishii, K; Kuwahara, M; Tsubone, H; Uchino, M, 2002)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19903 (37.50)18.7374
1990's1 (12.50)18.2507
2000's3 (37.50)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Qi, R1
Su, Y1
Pan, L1
Mao, Y1
Liang, L1
Dai, Z1
Wang, J1
Cai, Y1
Uchino, M2
Ishii, K2
Kuwahara, M2
Ebukuro, S2
Tsubone, H2
Beleslin, DB1
Krstić, SK1
Dozić, S1
Qin, XY1
Pilot, MA1
Thompson, H1
Scott, M1
Furukawa, N1
Hatano, M1
Fukuda, H1
Lang, IM1
Marvig, J1
Chen, JT1
Hirai, Y1
Hamada, T1
Fujimoto, I1
Yamauchi, K1
Hasumi, K1
Masubuchi, K1

Other Studies

8 other studies available for hexamethonium and Vomiting

ArticleYear
Anti-cholinergics mecamylamine and scopolamine alleviate motion sickness-induced gastrointestinal symptoms through both peripheral and central actions.
    Neuropharmacology, 2019, 03-01, Volume: 146

    Topics: Animals; Behavior, Animal; Cats; Cholinergic Antagonists; Hexamethonium; Hypothermia, Induced; Male;

2019
Role of the autonomic nervous system in emetic and cardiovascular responses in Suncus murinus.
    Autonomic neuroscience : basic & clinical, 2002, Sep-30, Volume: 100, Issue:1-2

    Topics: Acetylcholine; Animals; Atropine; Autonomic Nervous System; Blood Pressure; Cardiovascular System; D

2002
Central nicotinic receptors: vomiting, ear twitching and panting.
    Brain research bulletin, 1983, Volume: 11, Issue:3

    Topics: Animals; Body Temperature Regulation; Brain; Cats; Dimethylphenylpiperazinium Iodide; Female; Hexame

1983
Effects of cholinoceptor and 5-hydroxytryptamine3 receptor antagonism on erythromycin-induced canine intestinal motility disruption and emesis.
    British journal of pharmacology, 1993, Volume: 108, Issue:1

    Topics: Animals; Atropine; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; C

1993
Glutaminergic vagal afferents may mediate both retching and gastric adaptive relaxation in dogs.
    Autonomic neuroscience : basic & clinical, 2001, Oct-08, Volume: 93, Issue:1-2

    Topics: Action Potentials; Animals; Catheterization; Dizocilpine Maleate; Dogs; Esophagus; Excitatory Amino

2001
Role of autonomic nervous system for development and suppression of motion sickness in Suncus murinus.
    Autonomic neuroscience : basic & clinical, 2001, Dec-10, Volume: 94, Issue:1-2

    Topics: Acetylcholine; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Atropine; Autonomic Ner

2001
Functional localization of specific receptors mediating gastrointestinal motor correlates of vomiting.
    The American journal of physiology, 1989, Volume: 256, Issue:1 Pt 1

    Topics: Animals; Apomorphine; Atropine; Copper; Copper Sulfate; Digestive System; Dogs; Domperidone; Female;

1989
[Medical vagotomy: a new effective antiemetic therapy in cisplatin-induced nausea and vomiting].
    Nihon Sanka Fujinka Gakkai zasshi, 1987, Volume: 39, Issue:12

    Topics: Adult; Atropine; Cisplatin; Female; Genital Neoplasms, Female; Hexamethonium; Hexamethonium Compound

1987