hexamethonium has been researched along with Torsade de Pointes in 1 studies
Hexamethonium: A nicotinic cholinergic antagonist often referred to as the prototypical ganglionic blocker. It is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier. It has been used for a variety of therapeutic purposes including hypertension but, like the other ganglionic blockers, it has been replaced by more specific drugs for most purposes, although it is widely used a research tool.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ventricular arrhythmias, including Torsades de pointes in monkeys, were prevented in both species when HF oscillations were suppressed by autonomic blockade." | 1.42 | Short-term variability in QT interval and ventricular arrhythmias induced by dofetilide are dependent on high-frequency autonomic oscillations. ( Champeroux, P; Fowler, JS; Judé, S; Laigot-Barbé, C; Le Guennec, JY; Maurin, A; Richard, S; Sola, ML; Thireau, J, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Champeroux, P | 1 |
| Thireau, J | 1 |
| Judé, S | 1 |
| Laigot-Barbé, C | 1 |
| Maurin, A | 1 |
| Sola, ML | 1 |
| Fowler, JS | 1 |
| Richard, S | 1 |
| Le Guennec, JY | 1 |
1 other study available for hexamethonium and Torsade de Pointes
| Article | Year |
|---|---|
Short-term variability in QT interval and ventricular arrhythmias induced by dofetilide are dependent on high-frequency autonomic oscillations.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Autonomic Nervous System; Dogs; Electrophysio | 2015 |