Page last updated: 2024-10-28

hexamethonium and Sleep Apnea, Obstructive

hexamethonium has been researched along with Sleep Apnea, Obstructive in 1 studies

Hexamethonium: A nicotinic cholinergic antagonist often referred to as the prototypical ganglionic blocker. It is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier. It has been used for a variety of therapeutic purposes including hypertension but, like the other ganglionic blockers, it has been replaced by more specific drugs for most purposes, although it is widely used a research tool.

Sleep Apnea, Obstructive: A disorder characterized by recurrent apneas during sleep despite persistent respiratory efforts. It is due to upper airway obstruction. The respiratory pauses may induce HYPERCAPNIA or HYPOXIA. Cardiac arrhythmias and elevation of systemic and pulmonary arterial pressures may occur. Frequent partial arousals occur throughout sleep, resulting in relative SLEEP DEPRIVATION and daytime tiredness. Associated conditions include OBESITY; ACROMEGALY; MYXEDEMA; micrognathia; MYOTONIC DYSTROPHY; adenotonsilar dystrophy; and NEUROMUSCULAR DISEASES. (From Adams et al., Principles of Neurology, 6th ed, p395)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Schneider, H1
Schaub, CD1
Chen, CA1
Andreoni, KA1
Schwartz, AR1
Smith, PL1
Robotham, JL1
O'Donnell, CP1

Other Studies

1 other study available for hexamethonium and Sleep Apnea, Obstructive

ArticleYear
Neural and local effects of hypoxia on cardiovascular responses to obstructive apnea.
    Journal of applied physiology (Bethesda, Md. : 1985), 2000, Volume: 88, Issue:3

    Topics: Animals; Autonomic Nervous System; Blood Pressure; Cardiovascular System; Disease Models, Animal; Do

2000