Page last updated: 2024-10-28

hexamethonium and Shock, Septic

hexamethonium has been researched along with Shock, Septic in 1 studies

Hexamethonium: A nicotinic cholinergic antagonist often referred to as the prototypical ganglionic blocker. It is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier. It has been used for a variety of therapeutic purposes including hypertension but, like the other ganglionic blockers, it has been replaced by more specific drugs for most purposes, although it is widely used a research tool.

Shock, Septic: Sepsis associated with HYPOTENSION or hypoperfusion despite adequate fluid resuscitation. Perfusion abnormalities may include but are not limited to LACTIC ACIDOSIS; OLIGURIA; or acute alteration in mental status.

Research Excerpts

ExcerptRelevanceReference
"Choline treatment improved survival rate of rats in lethal endotoxin shock."1.35Choline or CDP-choline alters serum lipid responses to endotoxin in dogs and rats: involvement of the peripheral nicotinic acetylcholine receptors. ( Cansev, M; Ilcol, YO; Ulus, IH; Yilmaz, Z, 2009)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ilcol, YO1
Yilmaz, Z1
Cansev, M1
Ulus, IH1

Other Studies

1 other study available for hexamethonium and Shock, Septic

ArticleYear
Choline or CDP-choline alters serum lipid responses to endotoxin in dogs and rats: involvement of the peripheral nicotinic acetylcholine receptors.
    Shock (Augusta, Ga.), 2009, Volume: 32, Issue:3

    Topics: Animals; Atropine; Cholesterol; Choline; Cytidine Diphosphate Choline; Dogs; Endotoxins; Fatty Acids

2009