hexamethonium has been researched along with Pheochromocytoma in 1 studies
Hexamethonium: A nicotinic cholinergic antagonist often referred to as the prototypical ganglionic blocker. It is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier. It has been used for a variety of therapeutic purposes including hypertension but, like the other ganglionic blockers, it has been replaced by more specific drugs for most purposes, although it is widely used a research tool.
Pheochromocytoma: A usually benign, well-encapsulated, lobular, vascular tumor of chromaffin tissue of the ADRENAL MEDULLA or sympathetic paraganglia. The cardinal symptom, reflecting the increased secretion of EPINEPHRINE and NOREPINEPHRINE, is HYPERTENSION, which may be persistent or intermittent. During severe attacks, there may be HEADACHE; SWEATING, palpitation, apprehension, TREMOR; PALLOR or FLUSHING of the face, NAUSEA and VOMITING, pain in the CHEST and ABDOMEN, and paresthesias of the extremities. The incidence of malignancy is as low as 5% but the pathologic distinction between benign and malignant pheochromocytomas is not clear. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1298)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Effects of hirsutine, an alkaloid that produces a potent ganglion blocking effect, were investigated using rat pheochromocytoma PC12 cells." | 7.68 | Inhibition of ion channels by hirsutine in rat pheochromocytoma cells. ( Fujimori, K; Harada, M; Inoue, K; Nakazawa, K; Ohara-Imaizumi, M; Ozaki, Y; Takanaka, A; Watano, T, 1991) |
| "Effects of hirsutine, an alkaloid that produces a potent ganglion blocking effect, were investigated using rat pheochromocytoma PC12 cells." | 3.68 | Inhibition of ion channels by hirsutine in rat pheochromocytoma cells. ( Fujimori, K; Harada, M; Inoue, K; Nakazawa, K; Ohara-Imaizumi, M; Ozaki, Y; Takanaka, A; Watano, T, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nakazawa, K | 1 |
| Watano, T | 1 |
| Ohara-Imaizumi, M | 1 |
| Inoue, K | 1 |
| Fujimori, K | 1 |
| Ozaki, Y | 1 |
| Harada, M | 1 |
| Takanaka, A | 1 |
1 other study available for hexamethonium and Pheochromocytoma
| Article | Year |
|---|---|
Inhibition of ion channels by hirsutine in rat pheochromocytoma cells.
Topics: Adrenal Gland Neoplasms; Alkaloids; Animals; Calcium Channels; Dopamine; Electrophysiology; Ganglion | 1991 |