hexamethonium has been researched along with Inflammatory Bowel Diseases in 1 studies
Hexamethonium: A nicotinic cholinergic antagonist often referred to as the prototypical ganglionic blocker. It is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier. It has been used for a variety of therapeutic purposes including hypertension but, like the other ganglionic blockers, it has been replaced by more specific drugs for most purposes, although it is widely used a research tool.
Inflammatory Bowel Diseases: Chronic, non-specific inflammation of the GASTROINTESTINAL TRACT. Etiology may be genetic or environmental. This term includes CROHN DISEASE and ULCERATIVE COLITIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pretreatment with nicotine significantly decreased each of these markers in vagotomized mice with DSS colitis, and all markers except DAI and IL-6 in sham-operated DSS-treated mice." | 1.33 | The vagus nerve: a tonic inhibitory influence associated with inflammatory bowel disease in a murine model. ( Blennerhassett, P; Collins, SM; Ghia, JE; Kumar-Ondiveeran, H; Verdu, EF, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ghia, JE | 1 |
| Blennerhassett, P | 1 |
| Kumar-Ondiveeran, H | 1 |
| Verdu, EF | 1 |
| Collins, SM | 1 |
1 other study available for hexamethonium and Inflammatory Bowel Diseases
| Article | Year |
|---|---|
The vagus nerve: a tonic inhibitory influence associated with inflammatory bowel disease in a murine model.
Topics: Animals; Anticoagulants; Appetite Depressants; Dextran Sulfate; Dinitrofluorobenzene; Disease Models | 2006 |